LOCUS       DAVKBK010000001        83252 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVKBK010000001 DAVKBK010000000
VERSION     DAVKBK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.001"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            91..1983
                     /gene="pepO"
                     /locus_tag="VWX69_000001"
     CDS             91..1983
                     /gene="pepO"
                     /locus_tag="VWX69_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU9191419.1"
                     /translation="MTRYQDDFYDAINGKWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2106..2735)
                     /locus_tag="VWX69_000002"
     CDS             complement(2106..2735)
                     /locus_tag="VWX69_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9191420.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(3075..3317)
                     /locus_tag="VWX69_000003"
     CDS             complement(3075..3317)
                     /locus_tag="VWX69_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191421.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            3728..5950
                     /locus_tag="VWX69_000004"
     CDS             3728..5950
                     /locus_tag="VWX69_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU9191422.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5980..6423
                     /locus_tag="VWX69_000005"
     CDS             5980..6423
                     /locus_tag="VWX69_000005"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU9191423.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6462..6876)
                     /locus_tag="VWX69_000006"
                     /pseudo
     CDS             complement(6462..6876)
                     /locus_tag="VWX69_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7235..7597
                     /locus_tag="VWX69_000007"
     CDS             7235..7597
                     /locus_tag="VWX69_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191424.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            8005..8304
                     /locus_tag="VWX69_000008"
     CDS             8005..8304
                     /locus_tag="VWX69_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191425.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(8399..8836)
                     /locus_tag="VWX69_000009"
     CDS             complement(8399..8836)
                     /locus_tag="VWX69_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191426.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(8967..9602)
                     /locus_tag="VWX69_000010"
     CDS             complement(8967..9602)
                     /locus_tag="VWX69_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU9191427.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWENYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(9812..10462)
                     /locus_tag="VWX69_000011"
     CDS             complement(9812..10462)
                     /locus_tag="VWX69_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU9191428.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEILE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            10574..11416
                     /locus_tag="VWX69_000012"
     CDS             10574..11416
                     /locus_tag="VWX69_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9191429.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            11492..11929
                     /locus_tag="VWX69_000013"
     CDS             11492..11929
                     /locus_tag="VWX69_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU9191430.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            11997..12299
                     /locus_tag="VWX69_000014"
     CDS             11997..12299
                     /locus_tag="VWX69_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191431.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(12390..13463)
                     /locus_tag="VWX69_000015"
     CDS             complement(12390..13463)
                     /locus_tag="VWX69_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU9191432.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            13619..14296
                     /locus_tag="VWX69_000016"
     CDS             13619..14296
                     /locus_tag="VWX69_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9191433.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            14289..15263
                     /locus_tag="VWX69_000017"
     CDS             14289..15263
                     /locus_tag="VWX69_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9191434.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(15312..17255)
                     /gene="thrS"
                     /locus_tag="VWX69_000018"
     CDS             complement(15312..17255)
                     /gene="thrS"
                     /locus_tag="VWX69_000018"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU9191435.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFEKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(17313..17636)
                     /locus_tag="VWX69_000019"
     CDS             complement(17313..17636)
                     /locus_tag="VWX69_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU9191436.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDPLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(18067..18267)
                     /locus_tag="VWX69_000020"
     CDS             complement(18067..18267)
                     /locus_tag="VWX69_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191437.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            18505..19134
                     /locus_tag="VWX69_000021"
     CDS             18505..19134
                     /locus_tag="VWX69_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU9191438.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            19275..19544
                     /gene="rpsO"
                     /locus_tag="VWX69_000022"
     CDS             19275..19544
                     /gene="rpsO"
                     /locus_tag="VWX69_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU9191439.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            20359..20973
                     /locus_tag="VWX69_000023"
     CDS             20359..20973
                     /locus_tag="VWX69_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU9191440.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(21265..22014)
                     /locus_tag="VWX69_000024"
     CDS             complement(21265..22014)
                     /locus_tag="VWX69_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU9191441.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            22147..24483
                     /locus_tag="VWX69_000025"
     CDS             22147..24483
                     /locus_tag="VWX69_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU9191442.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLMETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDSIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            24585..25262
                     /locus_tag="VWX69_000026"
     CDS             24585..25262
                     /locus_tag="VWX69_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU9191443.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            25249..26046
                     /locus_tag="VWX69_000027"
     CDS             25249..26046
                     /locus_tag="VWX69_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU9191444.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            26063..27166
                     /locus_tag="VWX69_000028"
     CDS             26063..27166
                     /locus_tag="VWX69_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU9191445.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDNLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            27467..28486
                     /gene="galE"
                     /locus_tag="VWX69_000029"
     CDS             27467..28486
                     /gene="galE"
                     /locus_tag="VWX69_000029"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9191446.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            28488..29441
                     /locus_tag="VWX69_000030"
     CDS             28488..29441
                     /locus_tag="VWX69_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9191447.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(29503..29709)
                     /locus_tag="VWX69_000031"
     CDS             complement(29503..29709)
                     /locus_tag="VWX69_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU9191448.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            29761..30237
                     /locus_tag="VWX69_000032"
     CDS             29761..30237
                     /locus_tag="VWX69_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU9191449.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            30246..30917
                     /locus_tag="VWX69_000033"
     CDS             30246..30917
                     /locus_tag="VWX69_000033"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU9191450.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            31048..31386
                     /locus_tag="VWX69_000034"
     CDS             31048..31386
                     /locus_tag="VWX69_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU9191451.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            31389..32018
                     /locus_tag="VWX69_000035"
     CDS             31389..32018
                     /locus_tag="VWX69_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU9191452.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            32258..33409
                     /locus_tag="VWX69_000036"
     CDS             32258..33409
                     /locus_tag="VWX69_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9191453.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            33722..34471
                     /gene="truA"
                     /locus_tag="VWX69_000037"
     CDS             33722..34471
                     /gene="truA"
                     /locus_tag="VWX69_000037"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU9191454.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            34461..35234
                     /locus_tag="VWX69_000038"
     CDS             34461..35234
                     /locus_tag="VWX69_000038"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9191455.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            35212..35673
                     /locus_tag="VWX69_000039"
     CDS             35212..35673
                     /locus_tag="VWX69_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9191456.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            35900..37241
                     /locus_tag="VWX69_000040"
                     /pseudo
     CDS             35900..37241
                     /locus_tag="VWX69_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(37369..37572)
                     /locus_tag="VWX69_000041"
     CDS             complement(37369..37572)
                     /locus_tag="VWX69_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9191457.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(37565..38647)
                     /locus_tag="VWX69_000042"
     CDS             complement(37565..38647)
                     /locus_tag="VWX69_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9191458.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(38773..39555)
                     /locus_tag="VWX69_000043"
     CDS             complement(38773..39555)
                     /locus_tag="VWX69_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU9191459.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(39555..40898)
                     /locus_tag="VWX69_000044"
     CDS             complement(39555..40898)
                     /locus_tag="VWX69_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU9191460.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(40997..42313)
                     /locus_tag="VWX69_000045"
     CDS             complement(40997..42313)
                     /locus_tag="VWX69_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU9191461.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            42506..43732
                     /locus_tag="VWX69_000046"
     CDS             42506..43732
                     /locus_tag="VWX69_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU9191462.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            43931..45505
                     /locus_tag="VWX69_000047"
     CDS             43931..45505
                     /locus_tag="VWX69_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9191463.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRIEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            45770..46558
                     /gene="codY"
                     /locus_tag="VWX69_000048"
     CDS             45770..46558
                     /gene="codY"
                     /locus_tag="VWX69_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU9191464.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            46558..47133
                     /locus_tag="VWX69_000049"
     CDS             46558..47133
                     /locus_tag="VWX69_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9191465.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            47215..47300
                     /locus_tag="VWX69_000050"
     tRNA            47215..47300
                     /locus_tag="VWX69_000050"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47249..47251,aa:Leu,seq:aag)
     gene            47583..48713
                     /gene="ugpC"
                     /locus_tag="VWX69_000051"
     CDS             47583..48713
                     /gene="ugpC"
                     /locus_tag="VWX69_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU9191466.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            49214..49972
                     /locus_tag="VWX69_000052"
     CDS             49214..49972
                     /locus_tag="VWX69_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9191467.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            50060..50572
                     /locus_tag="VWX69_000053"
     CDS             50060..50572
                     /locus_tag="VWX69_000053"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU9191468.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            50754..51698
                     /locus_tag="VWX69_000054"
     CDS             50754..51698
                     /locus_tag="VWX69_000054"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU9191469.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            51707..52384
                     /locus_tag="VWX69_000055"
     CDS             51707..52384
                     /locus_tag="VWX69_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU9191470.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            52482..53240
                     /locus_tag="VWX69_000056"
     CDS             52482..53240
                     /locus_tag="VWX69_000056"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU9191471.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            53278..54783
                     /gene="lytC"
                     /locus_tag="VWX69_000057"
     CDS             53278..54783
                     /gene="lytC"
                     /locus_tag="VWX69_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU9191472.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            55281..55799
                     /locus_tag="VWX69_000058"
     CDS             55281..55799
                     /locus_tag="VWX69_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU9191473.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            55929..56435
                     /locus_tag="VWX69_000059"
     CDS             55929..56435
                     /locus_tag="VWX69_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU9191474.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            56435..56605
                     /locus_tag="VWX69_000060"
     CDS             56435..56605
                     /locus_tag="VWX69_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191475.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            56637..57869
                     /gene="clpX"
                     /locus_tag="VWX69_000061"
     CDS             56637..57869
                     /gene="clpX"
                     /locus_tag="VWX69_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU9191476.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            57878..58465
                     /locus_tag="VWX69_000062"
     CDS             57878..58465
                     /locus_tag="VWX69_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU9191477.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHAPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            58476..58856
                     /locus_tag="VWX69_000063"
     CDS             58476..58856
                     /locus_tag="VWX69_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU9191478.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            58908..59798
                     /gene="rapZ"
                     /locus_tag="VWX69_000064"
     CDS             58908..59798
                     /gene="rapZ"
                     /locus_tag="VWX69_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU9191479.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            59795..60772
                     /locus_tag="VWX69_000065"
     CDS             59795..60772
                     /locus_tag="VWX69_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU9191480.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            60769..61680
                     /gene="whiA"
                     /locus_tag="VWX69_000066"
     CDS             60769..61680
                     /gene="whiA"
                     /locus_tag="VWX69_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU9191481.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(61714..62682)
                     /locus_tag="VWX69_000067"
     CDS             complement(61714..62682)
                     /locus_tag="VWX69_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9191482.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEDYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQTLQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            62818..63675
                     /locus_tag="VWX69_000068"
     CDS             62818..63675
                     /locus_tag="VWX69_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU9191483.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            63662..64441
                     /locus_tag="VWX69_000069"
     CDS             63662..64441
                     /locus_tag="VWX69_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU9191484.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            64465..65817
                     /locus_tag="VWX69_000070"
     CDS             64465..65817
                     /locus_tag="VWX69_000070"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU9191485.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            65891..66265
                     /locus_tag="VWX69_000071"
     CDS             65891..66265
                     /locus_tag="VWX69_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU9191486.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            66267..67115
                     /locus_tag="VWX69_000072"
     CDS             66267..67115
                     /locus_tag="VWX69_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9191487.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            67392..68159
                     /locus_tag="VWX69_000073"
     CDS             67392..68159
                     /locus_tag="VWX69_000073"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU9191488.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            68171..69355
                     /locus_tag="VWX69_000074"
     CDS             68171..69355
                     /locus_tag="VWX69_000074"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU9191489.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVIKETYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            69352..71223
                     /locus_tag="VWX69_000075"
     CDS             69352..71223
                     /locus_tag="VWX69_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9191490.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAQDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(71366..72550)
                     /gene="mntE"
                     /locus_tag="VWX69_000076"
     CDS             complement(71366..72550)
                     /gene="mntE"
                     /locus_tag="VWX69_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU9191491.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            72854..75550
                     /locus_tag="VWX69_000077"
     CDS             72854..75550
                     /locus_tag="VWX69_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU9191492.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            75563..76354
                     /gene="yghU"
                     /locus_tag="VWX69_000078"
     CDS             75563..76354
                     /gene="yghU"
                     /locus_tag="VWX69_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU9191493.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLRTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            76470..76880
                     /locus_tag="VWX69_000079"
     CDS             76470..76880
                     /locus_tag="VWX69_000079"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9191494.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            76892..78487
                     /locus_tag="VWX69_000080"
     CDS             76892..78487
                     /locus_tag="VWX69_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191495.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGRTFEGQVGKDSYLKTFKVQ"
     gene            78666..78830
                     /locus_tag="VWX69_000081"
     CDS             78666..78830
                     /locus_tag="VWX69_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU9191496.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKENKDKFLSILTSLAGLALV
                     LVAVWLGWPK"
     gene            78909..79637
                     /gene="yaaA"
                     /locus_tag="VWX69_000082"
     CDS             78909..79637
                     /gene="yaaA"
                     /locus_tag="VWX69_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU9191497.1"
                     /translation="MKILIPTAKEMNTDLPSIETTLLRSESQAVLDALALYSASQLES
                     FYKVSAEKAAEECQNIQALKRQTAQHYPALKLFDGLMYRHIKRDKLTEVEQAYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDEAVKQEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(79688..81172)
                     /locus_tag="VWX69_000083"
     CDS             complement(79688..81172)
                     /locus_tag="VWX69_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9191498.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            81388..>83252
                     /locus_tag="VWX69_000084"
     CDS             81388..>83252
                     /locus_tag="VWX69_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9191499.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETK
                     PAVTTTERSAVDSAILPISTAAKVETTSAPASTNEILKPSLSLSDARQNPAIRKEDVD
                     RGYSGFRTAGSGFRAAGSGFRAAGPENKPILNPNNTIAFSDISQGLHSFRGIGHSRGG
                     REIHYDVTTVRRGNRLNFTIKYSGPGEFVNNNFILDKGDGFGNPSNATITSSNPRVRE
                     QSKSISQGANYVSHSGYSMTSATSTNTEQTIRFSLPIINPNGDLSVRLKPVTFNVDQG
                     GGGAATSNDPYSNSNYYHRANPLLLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQ
                     TRLVREGEKGQRQITYKVHRFGNETLLGLPISNRVTKEAKPRIMQIGVAKELIDTVKP
                     RVDQNKVGDTNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTG"
BASE COUNT        24599 a        15399 c        18873 g        24381 t
ORIGIN      
        1 gctaaaaaat aatagttaaa tggttattaa ttgcattccc tagtgatttt tgttaagata
       61 aatgcaaata caaatgaaag cgagaacaag atgacacgtt atcaagatga tttttatgat
      121 gctatcaatg gaaaatggca acagacagct gaaatcccag cagataagtc tcaaacagga
      181 ggttttgttg atttagacca ggaaattgaa gacctgatgc tggcgacaac agacaagtgg
      241 ttagcaggtg aagaagtgcc tgaggatgct atcttggaaa actttgtcaa ataccaccgc
      301 ctagttcgtg attttgacaa gagagaagct gacggtatca cacctgtctt accactcctt
      361 aaagaattcc aagaattgga aacttttgcg gattttacag ctaaactagc agagtttgag
      421 cttgcaggaa aaccaaactt ccttcctttt ggtgtatcgc cagactttat ggatgctaga
      481 atcaatgttc tatgggctag cgctccaagc acaatcttgc cagatacgac ctactatgca
      541 gaagaacatc ctcagcgcga agagctcttg actctttgga aagaaagcag cgcaaatctc
      601 ctcaaggctt atgatttctc tgatgaagaa attgaagact tgctagaaaa aagacttgaa
      661 ttggaccgcc gagttgcggc agtggtgctc tctaatgaag aaagttcaga atatgctaaa
      721 ctctatcatc catattctta cgaagatttc aagaaattcg cgcctgccct acctttggat
      781 gacttcttca aagcagttat tgggcaatta ccagacaagg ttattgtaga cgaggaacgt
      841 ttctggcaag cagcagagca attttacagt gaggaagcct ggtctctcct taaagcaacc
      901 ttgattttga gtgttgtcaa tctttcaacc agctatttaa cagaggatat ccgtgttttg
      961 tctggtgcct acagccgtgc cctttctgga gttccagagg caaaagataa ggtcaaagca
     1021 gcttatcatc tagcacagga acctttcaag caagccctgg ggctttggta cgcccgtgag
     1081 aagttctctc cagaagccaa ggcggatgtg gagaaaaaag tggcaaccat gattgatgtc
     1141 tataaggagc gtctgcttaa gaatgactgg ctcactccag aaacctgtaa acaggctatc
     1201 gtgaagctca atgtgatcaa accttatatt ggctatccag aagaattgcc tgcacgttac
     1261 aaggataagg tagtgaatga aactgccagt ctttttgaga atgctctagc ctttgcgcgt
     1321 gtggaaatca agcacagttg gagtaagtgg aaccagcctg tagactataa ggaatggggc
     1381 atgcctgctc atatggtcaa tgcctactac aatcctcaga agaacctgat tgtctttcca
     1441 gcggccattt tacaggcgcc tttctatgac ttgcatcagt catcttctgc taactacggt
     1501 ggtattgggg cagtgattgc ccatgaaatt tcccacgcct ttgatactaa cggggcttcc
     1561 tttgacgaaa atggtagcct caaggattgg tggacagaga gcgactatgc tgccttcaag
     1621 gagaaaacac aaaaagtcat tgaccaattt gatggacagg attcttatgg agcaaccatt
     1681 aacggtaaat tgactgtatc agaaaacgtg gctgacttgg gaggaatcgc agcagcgctt
     1741 gaagcagcta agagagaagc agacttctca gcagaagagt tcttctacaa cttcggtcgc
     1801 atctggcgca tgaaaggtcg accagaattt atgaaacttt tggctagcgt cgatgtgcac
     1861 gcaccagcca aactccgtgt caatgtgcaa gtaccaaact tcgacgattt ctttacaacc
     1921 tatgatgtca aagaaggaga cggaatgtgg cgttcaccag aggagcgcgt gattatttgg
     1981 taatacaaaa aatctagtca tcagaaaaaa ggcatccaat cacgtgtgaa aaccttgata
     2041 ggatgccttt tgtaatagaa agatttgctg gatagtttac ttaaatttcg attgtcatca
     2101 tcttgctaga aaaagggatt gaaggccttt tcgtgagcga tagtagtagc tggaccatgt
     2161 cctggataga catcgtagtt tggtagggtg aagagttggg tctggatact atgaaggagt
     2221 tgctccatgc taccagtcgg aaggtcggtc cgtccgatag tttcgcggaa tagagcatct
     2281 cccgtcaaga ctaggtgagc atcaggaaag actagggaaa caccaccgat agagtgccct
     2341 ggggtcggta gaaccttaaa acgaaattcc tctagttggt attcttcgtg aaagacaaag
     2401 gtgtgttctg caggttttgt gaccacatct gccatatcat cgtggcgagg gagaccggag
     2461 agattatcga caggagtgta gagccagctg gcttcgctct ctgcgatata gacaggagga
     2521 ttgccaaacg tctcgcgaac caagtccaga ctcatgatat ggtcataatg ggcgtgggtc
     2581 aagagaatag cacagatcgg tttgttgatc ttctcgattg tctgacgaat ggcttcccaa
     2641 tgactaccag gatcgacgac gatgaggtgc ttttcgcctt ctagataata ggtattttca
     2701 taggcaacag gattcacggt tttatggatt ttcatactaa ctccaatctc aaagaatgta
     2761 ctaatactct tcgaaaatct cttcaaaccg cgtcaacttt atctgcaacc tcaaagcagt
     2821 gctttgaaca gcctgcggct agctttctag tttgctcttt gattttcatt gagtataaat
     2881 taagtatagc acagttaggg agaataggta aggatttaaa atgaacttaa aaaccagcat
     2941 gactagatga agacaggctg gttatcaatt tatcaatatt ggaaaggtgt caattgccct
     3001 tcataggttg cataaactcc gtcattagct tgtttgatag acgtgatgtt tagagtgcta
     3061 ccgtagttgg cttctcattt gtcgctatat tcactataag ttatcctact gggcaggttc
     3121 tggtcgttag catagtattg aacgagtttt ttatagcttt gctggctgaa taggaacagg
     3181 cagcaaactc ctaacattag gagagcaaag atagaaatag cagttttttc ataggtattc
     3241 tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc ttcaaaaatc
     3301 tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg tcagtcttat
     3361 ctacaacctc aaagcagtgc tttgagcaac ctgtggctag tttcctagtt tgctctttga
     3421 ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg atacgagttc
     3481 caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct ttgggttaca
     3541 atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc taacttcgta
     3601 gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt ttttcttatt
     3661 ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga agaattggag
     3721 agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt taaccaaaga
     3781 atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg ctgttgaatg
     3841 ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta tccaagtggc
     3901 aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat tcttgcatga
     3961 tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg gtcctgatgt
     4021 gcgggtgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat cgatcgagga
     4081 gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca tccgcgttat
     4141 tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc ttcgaaaaga
     4201 caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccacttg cccatcgttt
     4261 ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc tcaatccaac
     4321 ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg aggccttggt
     4381 ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga aagggaagat
     4441 ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca agagaaaacg
     4501 gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc aaagtgatgt
     4561 ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc gcttcaaaga
     4621 ctatattgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg tttatggacc
     4681 aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg ctgagtacgg
     4741 ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca gcaaggaatc
     4801 agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg ctgatgatgc
     4861 taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt acgtttttac
     4921 cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt ttgcctacga
     4981 aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc gcatggttcc
     5041 actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc cgaactcctt
     5101 tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca ataagattcg
     5161 ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg agatgctgat
     5221 ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc gccacatgga
     5281 tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg ccattggttt
     5341 tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac gccgtgagga
     5401 agagcgtgcc aaggccaagg ctgaggcaga ggagcttgtc aaaggtggcg aggtcaaggt
     5461 tgaaaataaa gaaactctca aggtcaagca tgagggggga gtggttattg aaggtgcttc
     5521 tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg atattgttgg
     5581 ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga acctgcgtgc
     5641 ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt actctagctc
     5701 aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag gactgttgaa
     5761 cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca atgcccaacc
     5821 aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca acctctctac
     5881 actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg tcaaacggac
     5941 caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat tatccaacgg
     6001 gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa tcagggactt
     6061 ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta tgctgtgaga
     6121 aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct gtctgtcaaa
     6181 gatattgaag gagaaatcct ctccatttct cagtttaccc tctttgcgga tactaagaaa
     6241 ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga cttctatgat
     6301 gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggtatctt tggagcagat
     6361 atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac taaaaagaga
     6421 taagaaagac caagcccagt cggcttggtc tttctcatcg atcataaaat actccaaaaa
     6481 gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca gatgcgatag
     6541 gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg aatatcactt
     6601 aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa agcaaaacgc
     6661 cagaatctcg gtctaatctg ggaatagagt tgactaaagt ggtcacaaag ttggtttgaa
     6721 agataggtca atagcacggg atgaaagaaa atgagccaac cactataaat caaaatccag
     6781 tcccaagtaa gccccccttt taaatgtcaa aaataccagc atgattccat caatgacaag
     6841 gagttgaatg gttttgatga agatgatttt tttcatgcta aaacctcctt ttccttagag
     6901 acactcccct acaggtattt tagaatgtat attgcttaga tattccttat tttattagct
     6961 ttttaaggta ttaaagtagt tatataagtt tatgaagggt atcctatcct gcacggctaa
     7021 ttttgagttc gaaactgagg agtttataac tcaaaatttc gattaaatca gcatttaacg
     7081 atagtatgtt tgtcataaaa tgataaattt ttagattgtg gaattttttt caacttaatt
     7141 cttgattttt tttctaaatt gttatatact taatttacgg gataacagaa tcccgtcaga
     7201 aaggggtgat aatatgggaa aagagaatgt tagaatgcgt ttagcgtctg aatccagaca
     7261 gatattagat aagcttaaag atgatgttta caataaatta ggctatgaag taagctattc
     7321 cagtattgtt agtcaagctg ttagagaata cgttcctaaa aaagaacgta tagattggat
     7381 aaaattaaaa gagacagcta tacctttttc atcgttaaaa cagagcaata attgggagta
     7441 ccagacatca cttatgttag agaaagatgt attaatctta ctgtctgaac tacaaaattt
     7501 tttcttagat gtcttccaag cgaaacgtat acatagggca ttttgtatac gtctatgttt
     7561 gagagcgcaa tttttattaa gtaataatga ttcttaatac tatcaatatt aatgcggagt
     7621 gtaatgctcc gcaaaaataa aacctattac gggataaaaa cactacttta tttaggatgg
     7681 aaataagaac gtatttttta ctaatattgt ttagaaagga gtttctttat gacaccagaa
     7741 gaacaaactg ctttggaata cttttatgag gaactcgaga gttacggtga agatgagcaa
     7801 ggagaggtct ttgatttgta tgataattaa atcatctcca tagtttctga gaataattga
     7861 gaaactatac tctaaatcat aggtttatgt aaagctagat atacacaaaa ggaggtacga
     7921 atgaagatga aagctagagc ttcaccgttg aattgatttt gtttctagaa aaaatcaata
     7981 attagaaaaa tacgaggtaa aaaaatgaat agaaatgtac taaattttct gcgaacagaa
     8041 agtgctgaaa gagttagtct ttatatagac aaggctaata gattggaggg cgatgtaact
     8101 ctactcgcac ctagttctca agatttggaa gatattaaaa atgctatgtt ttccaatcct
     8161 aatctcgagc taaaagtagc gagactggat gtgatgaaga aaatagcata tgcttctaca
     8221 agaaatcatt atttaacagg ggctacgatt tttggggata tttcgaaagg aacatacaat
     8281 tgtgatccta aaagttatgt ctaatataag ggaggttaat ccctcccctt gtttttgaaa
     8341 atcgaaagga aaagtataaa aatgaaagtt aatgaatatt tctggagaac gagctgtctt
     8401 atactaaaaa agaagaaatc gataaaatag tatacgtgtt agagatgtgt ttgtcgtaaa
     8461 agtctggata gttttctctt aggtagtcag ctgtcatata ataaaaagta gaatggcaag
     8521 cagtgatgat tggcataaga gatgaaaaac gctgagaact aatgaaggct aagagaacaa
     8581 aaaatagaaa atcaatggtg agaaccccta aatagtagaa gcgaatcttt ttattgattt
     8641 gaggataaat ctcagcgaat tgatgtttga gtcggacgac caagagaaat agcaggagtc
     8701 cttgagcaag gaagaaaatt aaaccagaga gcaagagcca ctcaaaagat gtctcgagtc
     8761 tagtgataaa aaatgcaaat agtagcaaat caataactgc aattgctata aaatggattc
     8821 tatagagttt tttcatgaca agacctccct cttttatcta acttcattct actctaaaag
     8881 aatgggagtt acaactaaaa tgataaaaat agcagagggg agattctctt aagttggcta
     8941 gtattcttta tttgagtttc cttctattat ctaacttctt catcattcca gacaaataaa
     9001 gctccgattg cattgaggat ataaaagatg tatttaccga tattggcgaa gtttccttga
     9061 ataccagctt ttgtcagctg aacgaaattg taaatcaacc aaaagcccca ctgagttgtt
     9121 agttttaatg cattcaaagc attggcaatg agggacagtg caaaggcaat agttgttacg
     9181 taggcaagga gattcatctt gcccccatat ccgatatagt tggtcacaaa ggcaaagagg
     9241 aaggcgatga tggaaatgat gatggccgcc aattttacct gtttttggct catttggttg
     9301 ggtctgcctt cttgcgaagc tttccatttc tttatagcaa aggtataaat gaggaaggtg
     9361 acgggatagg taatgatggc cgccttattt ccaaggatat aatcaatagc accggacaaa
     9421 atggtattaa caataccaaa gtaattttcc catttgctta atttccccgt gaaacgagtg
     9481 gacaacatgg aaatcccaac gttggttacg gaaatcaatc caaagggtac aagagctgtc
     9541 catggtcccc agtctacaaa tttatcgagg cgtgagttga ggtaaccaga tgcaatcgca
     9601 atccaacgac caaagcaacc ccgaagaggt caaactattt agatgtagca aaaattttta
     9661 gtgatttttt cataggttaa actacctttc tttttttcaa atattctccc attttttttc
     9721 aaatattcta ccaccaaatg aaagtaaaat aaaatgatag aaataaaacc ctgaaaataa
     9781 aactttcagg gttggtaggg gacttgagaa attagttgat tttctcgaca tagagttgtt
     9841 ttgcaatgtc catattcact tgtaaatcct cgtcgttact gaggatagtg aaggtattgc
     9901 tgaagccatc aaactgctta acttggagct ggtcaccgat gtgaagtgag tgcttgtcca
     9961 gataatggag aatgtcaaaa ctatcgtgca tccgagtcag gcggtaggcg ccagcttcct
    10021 tgatatcagc tagtgggagg ttattgattt caacgaggag ttctcccttg gcaggaatag
    10081 ttcctccgtg ggggcaggtt ttagggaaac ctagcagttt atctagtctt tccacgaaca
    10141 ggtcagagac agtgtgttcc aagatctcag cttcctcgtg aatctggtca cttgtatagt
    10201 ctaaatgatg aactagaaaa acttcaatca agcggtgctt acgatagagc tcagagacca
    10261 gtttgagacc gaggtcagtc agtagatagc cacattcctt gtcctttagg atgagatttt
    10321 cacttttcat tcgtttgatc atttcagtta cggcaggggg agagacttgc atgcgagccg
    10381 caatttcctt gttggtaatc ttatgcaggt ctatgccaat ttcataaata cattttagat
    10441 agtcttcttt gtttggggtc attcgtttcc tcttgtctaa tatctttatc tagtatatca
    10501 aaaaaagcta gatttctcta gctgtgactt tttatgttat acttattgca agagaaaaaa
    10561 cgaggagatg gatatgacga aaatagctct tctttcagat attcatggaa ataccaccgc
    10621 cttggaggct gttttggcag atgctcggca gctaggagtg gatgaatact ggcttttggg
    10681 agatattctc atgccaggga cagggcgtag aaggattttg gacttgttgg atcaactacc
    10741 gattacggct agagttttgg gaaactggga agacagtctt tggcatggtg tccgtaagga
    10801 attggatagt actcgcccta gtcaacgcta tctcttgcgc cagtgccagt atgttttaga
    10861 ggaaatttcc ctagaagaaa ttgaagtgct ccacaatcaa cctcttcaaa ttcatcgtca
    10921 gtttggggat ttgacagtgg gaattagcca tcatctgcct gataagaact gggggcgaga
    10981 gttgattcat actggcaaac aagaggaatt tgaccgcttg gtgactcatc ctccctgtga
    11041 tattgctgtt tatggacaca ttcaccagca gttgcttcgt tacgggactg gtgggcaatt
    11101 gattgtcaat ccgggttcga ttggccaacc tttctttttg gacgctcagc tacggaagga
    11161 cttgcgggcc cagtatatga ttttggagtt tgatgacaag ggcctggtag atatggactt
    11221 ccgacgggta gattacgatg tggcagctga attgcagctg gctaaagacc tgagacttcc
    11281 ctattttgag gtttactatg aaagtctggt caatgggatc caccatactc atcatcagga
    11341 atttttgaga gaattggctc agaaagaggg ttgcgatcgg gagttagacg actggttgaa
    11401 aagtggtaac gattgacatt acaactaaaa agggtataat aatagaaaaa gaagagtaga
    11461 ggcagggtag cctcgtaaaa aggagaagag gatgcaaatt ccaagtagat ttaccattgc
    11521 gactcatatg ctgataatca ttgccctcga ggggaagaaa agcaaggtga ccagtgattt
    11581 tctggctgct agtgtcgggg tcaatcctgt cattatcaga aagatcttgt cccagttgaa
    11641 gaaggcagag ctgatttcag tagcgcgtgg aacgggcgga acagatattg tcaaggacct
    11701 taaggatatt agtcttttag atgtttatca ggcggtcgaa tgtcttggta agacaggtca
    11761 actcttcagt ttccatgaca atccgaatcc aaattgccct gtaggagctc atattcatga
    11821 tgttttggat caaaaattgg agagaattca gttgactatg gaggcagaac ttggtcaaac
    11881 cagtctagaa aaagtcgtgg ccgatgcaga gagtcagatg aaggattaag agggataaat
    11941 gccctctttt ttctttggat aattatgata aaatgtagct attaaaggag taagaaatgt
    12001 atctcgttat aggaattgta ttagccttta tagtgtcatt ttggaaggat aatagaagtt
    12061 tgtggaatcc agtattattt ttattatccc tcatttcaag ttatttttat ctatcctacc
    12121 ttttttataa aaatggatac gagaatgttc agttagcttt ttatgtattt gcctttgtct
    12181 tacttccttt tttgcttttt ctaagtggca tctttttaat ctataatggg gtcattttgt
    12241 tgaagcgaga gggacgttcc aagccccatt atctctcaat gctctttgat ttttattgac
    12301 tattagattc tatttaaaaa gacttagaat gcacatgaaa gtatgtattc taggtctttt
    12361 gttttgtata catttaattt tcaagagtat tatctatttt tccatgcctg gtaacgagta
    12421 tcaatcaata actgggtaag gcgacccaag gtttctcttt cttctggagt gagggattga
    12481 gcttggacaa agagatgatg aatgtattca agcgccttta aggaagccaa gtcattgata
    12541 gagctaatac cagcctcaag aatagtgcca aagaagaggt cgaagtagag ctgaagttct
    12601 tcgtcaggga ctgtggccac ccattcttta aaggttgtgt ctacttgctg gctatcactg
    12661 ttggtcttat ccagttggac gaagtgcttg tcctcaatct gccaactaaa ggtatcgtgc
    12721 tgggcgatgc cacccagggc agtactctga acgatgattt ggtgagcagg aatttccagc
    12781 atcataccga taatggaacc ttgtggaatg aatatcttgc ttctatccat tatcctttga
    12841 taacccgcag tctgtgtcaa ttcttgatgg agaccaggtg catcaaatgt ataaactgct
    12901 gtgatctgat tttgcaaact ttgctcaatt tggctagcag catagatagc gagatttcct
    12961 cccttggaat gcccagctag aataaccttt tgcttaggat gatgggcaaa aaagttcttt
    13021 aaatagcgaa gggcgtgctt ttgagcagga atttccttca tataggtcag gtggaaatct
    13081 tccttccagc caatgatact gtcatctgtc ccacgaaaga caatcagata ggtatcgagg
    13141 ctgacacgat aagtcatagc cgcaaattgc ttttgcagtt cagggtcgat gtcgttgata
    13201 aaatgggaga gtttgcaatt tttgaagcgc ttgtgttgag ccaatttatc taataattga
    13261 aggcgatttt tgctagtaag catggtgggc tctcttggaa cctgaggtgc tagatctaaa
    13321 agacgttgag gaagtgtgga gaccagatta tcaaaggaga ggtaggtgat ttctattaag
    13381 gttagaatgt ctaactcatt caagggaagg tcgtaataag aatcatatgc gacatctttc
    13441 agatagtcaa aaatattggc cataagagct cctttctttt tatttatctt agcaaatttc
    13501 cctcaaatta gctagtagca tagcctgttt gcactggcta aaaacaggct atttcaaatt
    13561 cagtttcaga ccatctagca tggaaaaatc tgttataata atggaaaagg agaagcgcat
    13621 gcacaagatt ttattaatag aagatgatca ggtcattcgt caacagattg ggaaaatgct
    13681 ctctgaatgg ggatttgaag tggtcctggt agaagacttt atggaagttt tgagtctatt
    13741 tgttcagtcg gaacctcatc tggtcctcat ggatattggt ttgcccttgt ttaatggtta
    13801 tcactggtgt caggaaatcc gcaagatttc caaggtacct atcatgtttc tttcttcgag
    13861 agaccaggct atggatattg tcatggcaat caatatgggg gcggatgact ttgtgaccaa
    13921 gccttttgac cagcaggttc ttttagctaa ggttcagggc ttgttgcgtc gttcctatga
    13981 gtttgggcgt gatgagagtt tgctggaata tgctggtgtt atcctcaata ccaaatccat
    14041 ggatttacat tatcaagggc aagtcttgaa tttgaccaag aatgaattcc agattttacg
    14101 cgtgttattt gagcatgcag gcaacatcgt agcacgtgac gacctgatgc gggaactttg
    14161 gaacagtgac tttttcattg atgataatac cctctctgtc aatgtggctc gtttgcgtaa
    14221 aaagttggag gagcagggat tggtaggatt tatcgagacc aagaaaggaa tagggtacgg
    14281 attgaagcat gcttgattgg aaacaatttt ttctagccta tctgcgctcc cgtagtcgtc
    14341 tttttatcta tctgctttct ttggcatttc ttgtcttact ctttcagttt ttatttgcca
    14401 gtctaggaat ttacttcctc tactttttct tcttgtgttg ctttgtaacc atcttatttt
    14461 tcacttggga catattggtg gaaatgcagg tctatcgcca ggaacttctc tatggagaga
    14521 gggaagccaa gtctcctttg gaaatagctt tagcagaaaa attagaagcg cgtgagatgg
    14581 aactctatca gcagaggtca aaagcagaaa gaaaactgac ggatttgctg gattactata
    14641 ccttgtgggt ccatcagata aagaccccca ttgcagccag tcaactctta gttgcagaag
    14701 tggtcgaccg ccaactgaag cagcagctag aacaggaaat tttcaaaatc gactcttata
    14761 ccaacctagt tttacagtac ctgcgtttag aaagtttcca tgatgatttg gtcttaaagc
    14821 aggttcaaat tgaggacttg gtcaaggaaa taattcgtaa atatgctctt ttctttattc
    14881 aaaaaggctt aaatgtcaat ctacatgacc ttgataaaga aatcgtgacg gataaaaagt
    14941 ggctgctagt ggttattgag caaatcatct caaacagtct caagtacacc aaggaaggtg
    15001 gtctggagat ttatatggat gaccaagagc tttgtatcaa agatacggga atcgggataa
    15061 aaaacagtga tgtcctccga gtatttgaac gtggcttttc aggatacaat ggccgtttga
    15121 cccagcagtc ctctggactt ggcctttatc tatctaagaa aatttctgaa gaactggggc
    15181 accagattcg tatcgagtct gaggtcggaa aaggaacgac agtgcggatt cagtttgctc
    15241 aagtgaactt agtccttgag taaaaataga tgagaaaaag cctccagatt ggaggctttt
    15301 atgctagact cttatttctc aacgcgtgat ttgttggcga tatcagctag gatagcttga
    15361 acaaaattat caactgagac agtttgtgtt tctttttggc cgtagcgacg aacgttgact
    15421 gtttcgtctt ccatttcttt gtctccaaca attaattggt aaggaatctt gctggtttgt
    15481 gaagcacgga tcttgaactg cattttttca ttgcgctcat ctacgtctgc acggacaccg
    15541 cggtcacgga gtttcttggc tacttcccaa gcgtagtcca cgtgtttttc gttagatact
    15601 gggataaggg ttacttggtg tggtgccagc catgttggga aggcaccctt gtagttctca
    15661 atcaagatag ctgtgaagcg ttccatagtt gagataaccc cacggtggat catgactgga
    15721 cggtgatctt cgccatcagc tccgatgtat ttgaggtcga agcgttctgg caacaagaaa
    15781 tcaagttgga tagtagaaag ggtttcttct tttccaaggg cagttttaat ctggatatcc
    15841 aattttggtc cgtagaaggc cgcttcacct tcggcttcaa agtagtccac gcccatttca
    15901 tcaagagctg cacgaagcat ggtttgggca ttttcccaca tctcatcgtt atcaaagtac
    15961 ttatgagtat cttgagggtc acgaagagag aggcggaagc ggtagtcagt caagttgaag
    16021 tcttcataaa catcgataat caactgaagg gcacgttgga attcttcttg gatttgttct
    16081 ggagtaacga ataggtgacc gtcgttgagt gacatttcac gtacacgttg aaggccagtg
    16141 agggcaccag atttttcgta acggtgcatc ataccgattt cagcgatacg gattggcaat
    16201 tcacggtaag agtgaacatg gtgtttgaaa acttggatgt ggtgcggaca gttcattgga
    16261 cgaaggacaa attcttcccc gtcacccatg tccatggttg ggaacatgtc ttcttggtaa
    16321 tgatcccagt ggccagaagt cttgtaaagc tcaacagaag caagtggtgg agtgtagacg
    16381 tgttggtagc cagaagccaa ctctttgttt acgatgtagc gttccaattc acgacggata
    16441 gtcgcaccat ttggcaacca gaatggcaaa ccttgtccca cttcttgtga aatcataaag
    16501 aggtcaagct ctttaccaag tttacggtgg tcacgttcct tagcttcttc acgcatttga
    16561 aggtagtttt tcaagtcttt cttttcaaac caagctgtac cgtagatacg ttgcatcata
    16621 gcgttgtcgc tgtttccacg ccagtacgca ccagctacat ggagaaggtg gaagatttgg
    16681 atacgacctg ttgatggaac gtgaggtcca cggcagaggt ctacatattc accctgacga
    16741 tagatagtca aaccgccttc gtcttctgag tgttcttcaa tcaattccaa cttgtaaggg
    16801 tcatttttga agatttcacg tgcctcgtct ttagtcactt cttcacgaat agatgggaag
    16861 ttttctttga cgattttttg catttcttct tcgatacgag gaaggtcttc gttagagatt
    16921 tgaccagctg tgttgtcagt atcgtagtag aaaccatctt cgatggctgg accaactccc
    16981 aagtgaatgt ctgggaaaag acgacgagct gcttgggcga acaagtgagc tgctgagtgg
    17041 cgcaagattg gaagggcatc ttcgtgatca ggtgtcacaa tttcgatgct tccatcttca
    17101 gtgatagcgc gagtagtgtc gatgagtttg ccgttgaatt taccagccaa ggctttttta
    17161 gctagggaat tgctgataga ttgggcaatt tcaaaagttg ttacgccaga ttcgaattca
    17221 cgaacagcgc catctgggaa agtaatgtta atcatgatgt tctccttttt tattatttca
    17281 tagtttctaa gcattgattt tttatcatca gactacttcc aagtcctaac gttcaattgc
    17341 ttttctttat cagagaggaa gttttccatt tccgtcagaa tgtctatatc caaacgttga
    17401 gaaagttcta atagccacca gatattttct gaaagttttt gttccagtgt gtagggtgtt
    17461 tcatcatagt agcgtccttg ctttgtcatc accagtcgtt ggaaatttcc aatatcatta
    17521 gataaagcca aggggtcttc ttctaccgtc cacttggaat catgatgctt aacttccagt
    17581 tcgtgataag cttgtcggat tgcccaactg cgctccacta attcttgcaa ctccataatt
    17641 agtatcctaa taaaaaaatg cgacatcctc gaaaggacgt cgcaacgtgg ttccaccttc
    17701 atttatgtac ctcaaaagag agggacacct ctgattggct ctaacgtggc caccgtttta
    17761 tgttttcata aaaaactcaa gagtagtatc agtttagact tcctatgcgt ttccagcaac
    17821 cacgcactct ctagtagaaa gggactaagt gacttgtctc tatggattat tatagcatga
    17881 ttgtgagatt tttcaaggat tttgtgaaag ttttttgttt ttcatttttt gtagaatatg
    17941 cttgatgcta ataccagaat ccatgcccac cagagcaact gtttcataga ttagcaagta
    18001 aattagtata aactcaccaa aggttatgat agtaaagtaa aagagcagtc cgttaccaac
    18061 taaccatcaa agtgagaaac ggaaacggta gctatagagt aacgatacaa tcaagattac
    18121 cagaggtgta aagaagagaa gattgtttat atagagttcc ttgagtgtaa gggggtcaga
    18181 aacaactagt aagaacaact cataaagtgg ccaataaaag aataatatga ccagatagta
    18241 ggggagatgg gaatagaatc tacgcatgat aatcacctcg ttttaaaaaa acagacaact
    18301 tagatctctt gctatgatta ttatagcatg tttaaaacaa gaaagtaaat ttgttggcaa
    18361 agaagatttt tttttcacta gaatcatggt tagttttctt ggtagaaata ttttgataat
    18421 aattaagcaa aactattgac attgattatt aagagtgtca caattgttgt aactaaaata
    18481 attacaataa gagaggtata aaaaatgaaa ctagcagtta ttgcagcaaa tggacaagcg
    18541 gggaaagcaa ttgttgaaga agtagtcaaa cgaggacatg aagtaacggc tattgttcgt
    18601 tctgaaaaca aaagtcaatc tgagtctatt attaaaaaag atttatttga gttgacaaaa
    18661 gatgatctta ctggatttga tgctgttatt tcagcgtttg gtgcttatac accagatacg
    18721 ctaccgctcc acagcaaatc aatcgaacta tttaatcagc ttcttgctgg aacacagaca
    18781 cgttttctag ttgtaggggg agcaggaagt ctttatatag atgaaacaaa aacgacacga
    18841 cttttagata cgtctgattt tcctgaagaa tttaagtcac tagcaaaagc tcaagcggat
    18901 gaattggatc ttcttcgtac aaaaaataat ctcaactgga cttttgtcag tcctgctgta
    18961 gattttattc ccgatggtga aaaaacagga aactacattc tagcaggaga aatttttact
    19021 actaatgaaa aaggaataag ccagattagt tatgcagatt atgctattgg attggtagat
    19081 gaacttgaaa aaggtcatca tataaaagaa cgtatctctt tacttgaaaa ataataacta
    19141 tgagagtatt aatgtttgac agaaaattta aatcttggta aaatagggat tgtcgtaaag
    19201 acaaataact tcttcttggt tacaggcatg ccaacctgtc actcggatga agccaaataa
    19261 aaaggagaaa catcatggca atctcaaaag agaaaaaaaa tgaaatcatt gcacaatatg
    19321 cacgtcacga aggtgataca ggttcagtag aggttcaagt tgctgtcctt acttgggaaa
    19381 tcaaccacct taacgaacac atcaaacaac acaaaaaaga ccacgctact taccgtggat
    19441 tgatgaaaaa aatcggtcgc cgtcgtaact tgcttgcata cttgcgtaaa aacgacgtta
    19501 accgttaccg tgagttgatc aactctctag gacttcgtcg ctaattcaag atacaaaggc
    19561 cgtcaaaaac acaaagcaaa aataggaaaa ttgacgaaga aacttcagtt tctaggagat
    19621 tttatctttt ttgccaagtg cttaggccgt gttcaattga gcatatcttg ataataaagc
    19681 tactctaaat tgggtagctt tgttgcgttg tcaccttacc tcgctatact caagtataat
    19741 cttcggttac ggttcctagc actgtaaggt aaaataaact agcttttctc ccttcgggga
    19801 gatttttttg tttcactgaa agtttcgtac gatcttcacc tcgtccccta gtctataaac
    19861 gatttatcta gcaagaatca tgatgctaag ggcgtcaaaa atccgtatga aaatagggaa
    19921 atgacacagt gttcgatgag cacaaggagt ttcatctttt tcactaggat tttagcccgg
    19981 gctaaaatca gctctctgac ttcagagggc ttttttattg aggttttatc ggtaacaatt
    20041 ttggagacta caaaaacctc aaatggtatc agctaattac accataaagg tgcgcagtta
    20101 ctcggctttt caagccgagt agctgtatgc aagcccccta gaagagccca ctctttacaa
    20161 agtaaagtat agtatgttat actttacatg gaagtagtca ctgaattcca gttagaaatt
    20221 actttgtaac tacgttttga ggaggagtaa aatgctttcc tacgttcgac attacccact
    20281 agcgatagct aaattaatgt gtctgtgctc tcctaaaatc tgctgattta ttactgacta
    20341 atacaggagg ttttttttat gggacagaca atcatatctg ctattggtgt ttatatttcc
    20401 accagtatcg attatttaat tattttaatt attttatttg cacagctatc acagaataaa
    20461 cagaaatggc atatttatgc ggggcaatat ctaggcacag gcttacttgt aggggcgagt
    20521 ttagttgctg cttatgtcgt taatttcgtg cctgaagaat ggatggttgg attgcttggt
    20581 ttaatcccta tctatttagg gattcgcttt gcaattgttg gagaagatgc ggaagaagaa
    20641 gaggaagaaa ttattgaaag attagaacaa agcaaggcaa atcaactgtt ttggacagtt
    20701 acattgctga caattgcgtc tggcggagat aatttaggta tctatatacc ttattttgct
    20761 tcgttagatt ggtcacagac cctcgtggcc ttgcttgtgt ttgtaatcgg cataattatc
    20821 ttttgcgaga ttagtcgggt gttatcctct attccgttaa tattcgagac aattgaaaaa
    20881 tacgagcgaa tcattgtgcc cttagtattc attctacttg gactatacat catgtatgaa
    20941 aatggcacga tagagacttt tctgatcgtg tagatttttt tgtttcacta ggattttagc
    21001 ccgagctcaa atcagctctc tgattttcag ggggcttttt cattgagtat aaatggacaa
    21061 tcttaaagtt actctattgt agagtggctt ttgatttgat taggagattc ttataaatat
    21121 agtaaaatga aataagaata ggacaaatcg atcaggacag tcaaatcgat ttctaaaaat
    21181 gttttagaag tagaggtgta ctattctagt tccaatctac tatataaatg aaaaccttag
    21241 ctgtttggcc aaggttcatt tcttctatgc aagttcttct cttttcttat ctgggttcca
    21301 gatgaagctt gcgataaagc taaagatgat ggttaggata gcgaggataa tagcaaggat
    21361 gagggcaggg atgcggataa accaccagag tggatttggt tttttatcat tgtgccattg
    21421 tttcgtttct tcgtccagac gttggaattc tgtttgaata cgattggcga ctgtttcaat
    21481 gccttcatca ttcattttct tgatatctga gatatcgatt ggatttccaa agttcatatc
    21541 gacacgttca cggctaatca agcccttcaa agtcatggga ccggtgtagg taaccggcat
    21601 gatacggacc ttggccattt tggcaatcag tgctgcgccc cccttgacat cgtttgagtg
    21661 gcggctacca cttggaaaca tgatgagaga gcggtcactt tttttgagaa cgttgatagg
    21721 atatttgatg gctgaggcgc tgggattttc acggtcgatg ggaaaggcgc cacacatacg
    21781 aatccaccaa ccaaagatac ggttggtaaa gagttctttt tttgccataa agatgaactg
    21841 ttttggcttg gtcgcaaagg ccatataaac aggatcccac caggtacggt gaggcgcaac
    21901 taaaatataa ttttcatctt gattaggaat tttatcagta ttatgatagt gagcattgcc
    21961 attgatggac cataagagca atacaactaa tccacgcaaa taagtataaa acatgcgatc
    22021 tccttcgatt gttttcttgt tattattata ccttatcaaa ggagggctgg caaacttttc
    22081 ccttgactag atacatattt aggatgaaat tagaattctg ttaaaaaaaa tgatataata
    22141 gaatttatgg ataaaaataa gattatggga ttaacccaaa gagaagtcaa ggaaagacag
    22201 gctgagggtt tggtcaatga ctttaccgca tcagccagta ccagcacttg gcaaatcgtt
    22261 aaacgaaatg tctttaccct ttttaacgct ttgaactttg ccattgcttt ggctcttgcc
    22321 tttgtgcagg cttggagcaa tctggtcttc tttgctgtta tctgctttaa cgctttttct
    22381 gggattgtga ccgagctacg agccaaacac atggtggaca agctcaatct catgaccaag
    22441 gaaaaggtca aaaccatccg tgatggtcag gaagttgctc ttaatcctga agaattagtg
    22501 ctaggagatg tcattcgttt gtctgcagga gagcagattc ctagtgatgc cttggttttg
    22561 gaaggctttg cggaagtcaa tgaagccatg ttaacgggag aaagtgattt ggtgcaaaag
    22621 gaagttgacg gcttactttt gtcaggaagt ttcctagcca gtgggtcagt tttatctcaa
    22681 gttcaccatg tcggtgcaga caactatgct gccaaactca tgcttgaggc taagaccgtt
    22741 aaacccatca actcccgtat catgaaatcg ctggacaagt tggctggttt tactgggaag
    22801 attatcattc cctttggtct ggctctcttg ctggaagcct tgcttttaaa aggcctgcct
    22861 ctcaagtcat ccgttgtaaa ctcgtcgaca gctcttttgg gaatgttgcc taagggaatt
    22921 gcccttttga ccattacttc gctcttgact gcagtgatta agttgggctt gaaaaaggtc
    22981 ttggtgcagg agatgtactc tgttgagacc ttggcgcgcg tggatatgct ctgtctggac
    23041 aagacgggta ccatcaccca aggaaagatg caggtggagg ctgttcttcc gttgatggaa
    23101 acgtatggtg aagaggctat tgccagcatc ttgactagct acatggccca tagtgaggat
    23161 aagaatccaa ctgcccaagc cattcgccag cgttttgtgg gagatgttgc ttatcctatg
    23221 atttccaatc ttcccttctc gagcgaccgc aagtgggggg ctatggagtt agaaggcttg
    23281 gggacagttt tcttaggggc gcctgagatg ttgctggatt ctgaagtccc agaagccagg
    23341 gaggccttgg agagaggatc acgtgtcttg gtcttagctc tcagtcagga gaaattagac
    23401 catcacaaac cacagaaacc atctgatatt caggctctag ccttgctgga aatcttggac
    23461 tccattcgag agggagcagc agagacgctg gactatctcc gttctcagga ggtaggactc
    23521 aagattatct ctggtgacaa tccagttacg gtgtccagca ttgcccagaa ggctggtttt
    23581 gcggactatc acaactatgt agattgctca aaaatcaccg atgaggaatt gatggccatg
    23641 gcggaggaga cagctatttt cggacgtgtt tcccctcatc aaaagaaact catcatccaa
    23701 acgttgaaaa aagcgggtca tacaacggct atgacagggg acggggttaa tgatatcttg
    23761 gcccttcgtg aggcggattg ttctatcgtg atggcggagg gggatccagc aacccgtcag
    23821 attgccaatc tggttctctt gaactcagac tttaatgatg ttcctgagat tctcttcgag
    23881 ggtcgtcgcg tggtcaataa cattgcccac atcgccccga ttttcttgat aaagaccatc
    23941 tattccttcc tgttagcagt catctgtatt gccagtgctt tactaggtcg gtcagagtgg
    24001 attttgattt tccccttcat tccgatccag attaccatga ttgaccagtt tgtggaaggt
    24061 ttcccaccat tcgttctgac ttttgagcga aatatcaaac ctgttgagca gaatttcctc
    24121 agaaaatcca tgcttcgtgc cctaccaagc gctctcatgg tcgtctttag cgtcctgttt
    24181 gtgaaaatat ttgggagtag ccaaggttgg tctgagttag aaatctcaac tctcctctat
    24241 tatctcttgg ggtcaattgg tttcttatcc gtatttagag cctgcatgcc atttacccta
    24301 tggcgtgtcc tcttgattgt ttggtcagta ggaggtttcc tagccacagc tctcttccca
    24361 agaatccaaa aactgcttga aatttcaacc ttaacaggac aaacattacc tgtttatggt
    24421 gtcatgatgt tggtctttac cgtgattttc atcctgacca gtcgctatca agccagaaaa
    24481 taaagaaagg ctgcaatctg tggattgcag tttttttagg tacaagattg ccagtcgaaa
    24541 tgtggtataa taagaggtaa tagagttttg gaaagtgaga gaagatgatt tcaaagagat
    24601 tagaattggt agcttccttt gtgtcacagg gggctatttt actagatgtg ggaagtgacc
    24661 atgcttatct gcctatcgag ttggttgaga gaggccaaat caaaagcgct attgcaggtg
    24721 aggtggtgga aggtccctat cagtctgcgg ttaaaaatgt tgaggctcac ggcctaaagg
    24781 agaaaatcca agtccgttta gccaatggct tggcagcttt tgaagagact gaccaagtgt
    24841 ctgtcattac cattgctggc atgggtggtc gtttgattgc taggatttta gaagaaggtt
    24901 tggggaagtt agctaatgta gagcgtttga tcctccagcc caataatcgt gaagacgact
    24961 tgcgtatctg gctacaggat catggattcc agattgtagc agaaagcatt ttagaagaag
    25021 ctggaaagtt ttatgagatt ttggtggtgg aagcaggaca aatgaagcta tcagccagtg
    25081 atgttcgctt tggtcccttc ttgtccaaag aagtcagtcc agtatttgtc caaaaatggc
    25141 aaaaagaagc tgagaagcta gagttcgccc tcggacaaat cccagaaaaa aatctggaag
    25201 aacgtcaagt tctagtagat aagattcaag ctatcaagga ggtgctccat gttagcaagt
    25261 gaagtgatcc aagcttatga agccttttgc cctcaggaat tttctatgga gggagacagc
    25321 cgtggtctgc aaattggcac tttagacaag ggtatccaaa gggtcatggt tgccctcgat
    25381 attcgtgaag agacggtggc agaggctatt gaaaagggtg tggacttgat tatcgtcaag
    25441 cacgcgccta tctttcgtcc tatcaaggac ttgcttgcca gccgtccgca aaatcagatt
    25501 tacatcgacc tgattaagca tgatatcgca gtttatgtca gccataccaa tattgatatc
    25561 gttgaaaatg ggctcaatga ctggttttgt cagatgctag gaatcgagga gacgacttat
    25621 ctgcaggaaa caggtccaga acgtggaatt ggacgtattg ggaatattca gcctcagaca
    25681 ttttgggaat tggcccaaca ggtcaagcaa gtctttgacc tagatagcct tcgaatggtg
    25741 cattatcaag agaatgattt gcagaagcct atttcaagag tagcaatttg tggtggaagc
    25801 gggcagtctt tctataagga tgctttggca aagggggcag atgtctatat cactggtgat
    25861 atctactacc atactgctca ggatatgctg tctgatggct tgttagcatt ggatccaggt
    25921 cactatatcg aagtgctttt tgtggaaaaa atcgcagcac tccttactca atggaaagag
    25981 aaaaaaggct gggaactaga gattttacct agtcaagcat cgaccaatcc tttccgtcat
    26041 atctagttag aaagtgaaga caatgaaaaa agttgccatt attggagcag gaattgtggg
    26101 agcaacagct gcctactacc tctcgagaga aagtgaccta gaggtgaccg tttttgacca
    26161 tgagcaaggt caagccacca aggccgcagc aggaattatc agtccttggt tttccaaacg
    26221 ccgtaataaa gcctggtaca agatggcgcg cttgggggct gatttttatg tggatttatt
    26281 agctgattta gagaaatcag gacaagaaat cgacttttac cagcgttcgg gagtctttct
    26341 cttgaaaaag gatgaatcca agttggaaga actctatcaa ctggctctcc agcgcagaga
    26401 agaatctccc ctgataggcc agttagccat tctggatcaa gcatcagcta atgaattatt
    26461 ccctggcttg cagggattcg acaacttgct ctatgcttct ggtggagcga gagtagatgg
    26521 ccaactcttg gtaactcgtc tgctagaagc cagtcatgtc aagttggtca aagaaaaagt
    26581 gactctgaca ctcttatcat caggctacca gattggcgaa gaggtgtttg atcaggttat
    26641 tttggcaacg ggagcttggt tgggggacat gttagaacct ttaggttatg aagtggatgt
    26701 ccgtcctcaa aaaggacaac tacgagatta tcagcttgcc caagacatgg aagattaccc
    26761 tgttgtcatg ccagaagggg agtgggattt gattcccttt gcaggtggga aattatcctt
    26821 gggcgctacc catgaaaatg acatgggatt tgatttgacg gtagatgaac ccttgctcca
    26881 acaaatggag gaggcggcct tgcctcatta cccagtttta gctagagtga cttcaagggc
    26941 tgagcgtgtg ggaatccgtg cctataccag tgatttctct cccttctttg ggcaggtgcc
    27001 agaattggca ggtgtctatg cagccagtgg actaggttca tcaggcctca caactggtcc
    27061 tatcattggt taccatctag cccaactgat ccaagacaag gagttgacct tggaccctct
    27121 aaattaccca attgaaaact atgtcaaacg agtaaaaagc gaataatact caatgaaaat
    27181 caaagaacaa actaggtaac tagccgcggg ttactcaaag cactgctttg aggttgtgga
    27241 tagaactgac gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt
    27301 cagtaaccat acccatggca aggcgacgtt gacgtggttt gaattggatt ttcgaagagt
    27361 ataagcattt tactgaaatt ttatcaggta gtttaggatg gcaaatgaca ttccctgtca
    27421 aaaatggtaa aataagaaaa aataatctga gaatcgagga aaaaagatgc aagaaaagat
    27481 tttggtaact ggtggtgccg gttttattgg aacccacact gttattgaat tgatccaagc
    27541 aggccatcaa gttgttgtgg tggataatct tgtcaatagc aatcgtaaga gtttagaagt
    27601 tgttgaaaga atcacaggag ttgagattcc tttctatgag gcagatattc gtgacacagc
    27661 taccctcaga gatattttca agcaggaaga accgactggt gtcattcact ttgctggttt
    27721 gaaggctgtt ggcgaatcaa cacgtatccc tcttgcctac tatgacaaca atatcgctgg
    27781 aactgtcagc cttttgaaag ccatggaaga aaacaactgt aaaaacatca tcttcagttc
    27841 ttctgcgaca gtttacgggg atccgcacac agtgcccatc ttggaagatt tcccactttc
    27901 agtgaccaac ccatacggtc gtactaagct catgctagag gaaattttga ctgatattta
    27961 caaagcagac tcagaatgga atgttgtctt gcttcgttac tttaacccaa tcggagccca
    28021 tgagagtggt gatttgggag aaaatccaaa cggtattcca aacaatctct tgccatatgt
    28081 gactcaagta gccgttggaa aattagagca agtgcaagtg tttggagacg attacgatac
    28141 ggaagatgga acaggtgttc gtgactatat ccacgttgtc gatttggcta agggtcacgt
    28201 tgcagctttg aaaaaaatcc aaaaaggttc aggactaaac gtttataacc ttggaactgg
    28261 taaaggttac tcagttcttg aaattatcca aaacatggaa aaagcggtgg gccgtcctat
    28321 tccttaccgc atcgtagaac gtcgcccagg tgatatcgct gcctgctact cagacccggc
    28381 aaaagctaaa gcagaactcg gttgggaagc agaactcgac atcacccaaa tgtgtgaaga
    28441 cgcatggcgt tggcaaagca agcatccaaa tggatttgaa gactaagatg atgatttcaa
    28501 tcatcgtccc ttgtttaaac gaagaggaag tacttcctct tttttatcag gctctggaag
    28561 ctttacttcc agatttggaa acagaaatcg agtatgtctt tgtcgatgat ggatcaagtg
    28621 atgggacctt ggaactctta aaggcctatc gggagcaaaa tccggcagtc cattatattt
    28681 ctttctctcg aaattttggc aaagaagcag ccctttatgc aggcttgcaa tatgcgacag
    28741 gagatttggt ggtggtgatg gatgcagacc tccaagatcc tcctagtatg ttgtttgaga
    28801 tgaaaaatgt actagacaaa aatgtagact tggactgcgt tgggacacgg agaactagtc
    28861 gggagggaga acccttcttt cgcagtttct gtgctgttct cttttatcgc ctcatgcaaa
    28921 aaatcagccc agtagctctg ccgtcgggtg tccgtgattt tcgtatgatg agaaggtctg
    28981 tagtcgatgc cattttaagc ttgaccgagt ccaatcgttt ttcaaagggg ctcttcgcct
    29041 gggtgggttt caaaacctac tatttggact atccaaatgt cgaaaggcag gctggcaaga
    29101 ccagttggag ttttaggcaa ctcttttttt actccattga agggattgtt aatttttcag
    29161 atttcccttt gactatagcc tttgtagctg gtctcctatc ttgttttctt tctctgctga
    29221 tgaccttttt tgttgtggtt cggaccctca ttttgggcaa tccgacatct ggttggacct
    29281 ctctgatggc tgttattctc tttcttggag gcattcaact cttgaccatt gggattctcg
    29341 gtaagtatat cagtaagatt tatttagaga ctaaaaaaag accactttat cttatcaaag
    29401 aaaaaagtga ccttcctgat tttacagaaa aaataaagtg aaaagactat aattttacat
    29461 ggaaatgtgc taaactagag ggagtggatt atcgccattg atttaggctt cctggtttcc
    29521 aatcagggcg cgagttgggc aatttttaac agcctctaag acatcctgac taggagaaat
    29581 ttctttttcc agttggtcag ggtcatcgta aaaacgcacg attccattat cgtggtaatc
    29641 aaataaatca gaataagttt ggcaaagtcc acaggcgata catcgttcag gtataagtgt
    29701 gattttcatg ttcatattta tattgtaata agaaaagtaa aaaaaaacaa ggagtaaggt
    29761 atggcaaaag aaccgtggca agaagatatt tatgatcaag aagaatcaag agcagggcgt
    29821 cggcatcgaa accacggagg ggctgatagg atggctaatc gtattttgac gatcctagct
    29881 agtattttct ttgtaattgt ggtggtgatg gtcatcgttc tcatctatct atcatcgggg
    29941 gggagtaatc gcacagcagc cttaaaagac tttcatgatt ctgatgcaag tgtagtacaa
    30001 atctcatctt caagcagttc tcagcctgag cagagttcag agccagaatc tacttctagt
    30061 agttcagaag aagctgctaa tcctgaagga acgattaaag ttctcgcagg agaaggggaa
    30121 gcagctattg ccgctcgtgc aggaatctcc attgctcagt tagaggcctt gaatcctggg
    30181 cacatggcta caggatcttg gtttgctaat ccaggtgatg ttataaaaat aaaataggag
    30241 ccgatatgaa aacaattcaa attgctattg atggtcctgc ttccagcggt aagagtacgg
    30301 tcgcaaagat tattgctaag gattttgggt tcacctacct tgatacagga gctatgtatc
    30361 gtgcagcgac ctatatggct cttaagaacc aattaggagt tgaagaagtc gaagcccttc
    30421 tagccttgtt ggaccagcat ccaatcagct ttggacgttc agaaactgga gaccagcttg
    30481 tttttgtagg agatgtggat attacccatc ctatccgtga aaatgaagtg accaatcatg
    30541 tttctgctat tgcagcaatt cctgaagtgc gtgagaaact ggtttctctc caacaagaaa
    30601 ttgcccagca aggcgggatt gtcatggatg gtcgcgatat tggaactgtt gtattgccac
    30661 aagcagaatt gaaaattttc ctagtagctt ctgttgatga gagagcagag cgtcgttaca
    30721 aggaaaatat tgccaaggga attgaaacag accttgaaac cctaaaaaag gaaattgctg
    30781 cgcgtgacta caaggatagt catcgtgaga cttctcctct caaacaagca gaggatgctg
    30841 tctaccttga tacaactggt ttgaacattc aagaagtagt tgaaaaaatc aaagcagaag
    30901 ctgaaaaaag aatgtaaatg tagaaaagcc gatagattga tatcggtttt tttctaaatt
    30961 tgtcaaaatg ctgattttag ggtataatag ttgctgttcg agaaattttg attttcaaag
    31021 aatagtgaat gatgataagg agaaaccatg aacaatttac caaattgtcc aaaatgtaac
    31081 tcagagtatg tctacgaaga cggtgcccta ctggtttgcc cagagtgtgc tcatgagtgg
    31141 aatcctgctg aagttgcaga agtagaagaa ggtcttgtcg ctatcgatgc caacggaaat
    31201 aaattgactg atggtgatac agtaactctc atcaaggact tgaaagtaaa aggtgcgcca
    31261 aaagatttga aacaagggac gcgcgtgaaa aatatccgca tcgtagaagg cgatcacaat
    31321 atcgactgta agattgatgg ttttggtgcc atgaaactta aatcagagtt tgtgaggaag
    31381 atttaagcat gtcaaaacac tataaacttg tattttatag ccgtatcttc ttgtttctag
    31441 cggcttttac gggagtttat cttgaaatta ctaggcatgg tggttttggg atgcttctct
    31501 attacacggt tctgtccaac ctcttggtaa ctatttttac cctttatctt ctaaaggtta
    31561 tgagccgtgt aggtgaaaat tggcaaaggc caagtctctt gcgcttaaaa ggtggggtca
    31621 ccatgagtat catgattacc tgtgtgattt accatttcct cttggcgccc attgcgacta
    31681 atttctatac cctagaaaat ttcctttgcc actatatcgt tcccatctgg tttttagcgg
    31741 ataccctctt ttttgacaaa cagggtcaat acaagatttg ggatccagca gtgtggacca
    31801 ttttaccctt tctgtatatg atgtttgctc tttttaatgg cttggttcta aaactcaata
    31861 ttccaaatgc caaggataat cctttccctt acttcttttt gaatgtgaac aagggttgga
    31921 atgttgtgtt taagtggtgt ctgattatct ttgttgccta tatggtagca ggatttattt
    31981 tctactttat caagcaaatc aagagaaagt catcctaata ctcttcgaaa atctcttcaa
    32041 accacgttag tttccatctg caacctcaaa acactgtttt gaacaacctg cggctagctt
    32101 tctagtttgc tctttgattt tcattgagta tgagatacaa gggattcatt ttcgaattta
    32161 agaaggagtc tacaaaccaa tgaggcttct tcttttcttg cttatttgat aactatcaaa
    32221 aaagtagaag attaagagaa atatagaaag agatttcatg aaacaatttt tagaacgggc
    32281 cagcattttg gctctctccc tcgttttgat tacctccttt tccatttcga gtgccctacc
    32341 agccatgttt gactattatc agggttattc taaggaacaa attgagctct tggtgagctt
    32401 gccttccttt ggaatcatga tgatgttact gctaaatggt ttcttagaaa aaatatttcc
    32461 tgagcgctta cagattagtt tgggcttgct gattttatca ttgagcggta cagctccctt
    32521 ctggtaccaa gcctatccct ttgtctttgg aacacggctt ctctttggtt tgggtcttgg
    32581 gatgatcaat gccaaggcca tttctattat cagtgaacgc taccaaggaa aaaggcgaat
    32641 tcagatgtta gggctacgcg cttctgcaga ggtcgttgga gcttctctca ttaccttggc
    32701 cgtcggtcag ttgttggcct ttggttggac agctatcttt ctagcctata gtgctggatt
    32761 tttggtgatg cccctttatc tgctctttgt cccttatgga aaatcaaaga aagaagtcaa
    32821 gaaaagagcg aaggaagcaa gtcgtttaac tcgagaaatg aaaggcttga tttttacctt
    32881 agctatcgaa gcggcagttg tagtttgtac caatacagct attaccatcc gtattccaag
    32941 tttgatggtg gaaagaggat tgggggatgc ccagttatct agttttgttc ttagtatcat
    33001 gcagttgatc gggattgtgg ctggggtgag tttttctttc ttgatttcta tctttaaaga
    33061 gaaactgctc ctctggtctg gtattacctt tggcttgggg caaatcgtga ttgccttgtc
    33121 ttcatccttg tgggtggtag tagcaggaag tgttctggct ggatttgcct atagtgtagt
    33181 cttgacgacg gtctttcaac ttgtctctga acgaattcca gctaaactcc tcaatcaagc
    33241 aacttcattt gctgtattag gctgtagttt cggagccttt acgaccccat ttgttctagg
    33301 tgcaattggc ttactaactc acaatgggat gttggtcttt agtatcttag gaggttggtt
    33361 gattgtaatc tctatctttg tcatgtacct acttcagaag agagcttagg attgattcct
    33421 aagtttttct tttgatactc aatgaaaatc aaagagcata gttgattgag tttggaatag
    33481 tacgctgtag ctgctaaaat atttctagaa attaatttga cttttctaat agagttattc
    33541 atatcttatt tcaatctact atagaaagct agccgcaggt tgctcaaaat agtgttttga
    33601 ggttgcagat ggaaactgac gtggtttgaa gagattttcg aagagtatga gatttttata
    33661 cccatacaat atttgtttta ggtccttgtt tacagactaa tttcttgata aaatagaggt
    33721 tatgacgaga tataaagcaa ctatttccta tgatggttat gcctttgctg gctttcagcg
    33781 ccagtctcat gcgcgtagcg ttcaggaaga aattgaaaaa accttgacca gattaaataa
    33841 agggcaaacc attactgttc acggtgctgg taggacagat agtggggttc atgccctggg
    33901 acaggtcatt cattttgacc tgccttatca gatggatgag gagaaactcc gttttgcctt
    33961 ggatacccag tctcctgaag atattgatgt gatttcgatt gagcttgtgg cagatgattt
    34021 tcattgccgt tatgccaaac atagcaagac ctatgagttt attgtggata gaggacgtcc
    34081 caaaaatcct atgcgccgtc actatgccac ccactttccc tacccactcg atgtggaacg
    34141 aatgcagatt gcaatcaaaa agctagaggg aacccatgat tttaccggtt ttacagcctc
    34201 tgggactagt gtagaggata aggttcgcac catcacagaa gctagtttaa tagtcgatga
    34261 gacaggacaa tttttgacct ttaccttttc aggaaatggt ttcttgtata aacagattcg
    34321 caatatggtg gggactcttc tcaaaatcgg taacaaccgc atgccagtag agcagattga
    34381 tctcatcttg gagaagaagg acaggcaact tgcaggtccc actgcagcac caaatggttt
    34441 gtatttaaag gagattcgtt atgaagaata atcgtatttt agcactttct ggaaatgata
    34501 tttttagtgg tggtggactg tcagctgatt tggctaccta taccttgaac ggcttgcatg
    34561 ggtttgtagc agtgacttgt ttgacagcct tgacagaaaa aggatttgaa gtctttccaa
    34621 ctgatgatac catttttcaa catgaattag atagcttacg tgatgtggaa tttgggggaa
    34681 ttaagattgg tcttctccct actgtcagtg tggctgagaa ggccttggac tttatcaaac
    34741 aacgcccagg agtacctgtg gtgttggatc ctgtcttggt ctgcaaggaa acgcatgatg
    34801 tagctgtcag tgagctctgc caagagttga ttcgcttttt cccttatgtc agtgtgatta
    34861 cgcctaatct cccagaagca gaattattat ccggtcagga aattaaaacc ttggaagaca
    34921 tgaaaactgc agcgcagaaa ttgcatgatt taggagcgcc agcagtcatt atcaagggag
    34981 gcaatcgtct tagtcaggac aaggctgtgg atgtctttta tgatggacag acctttacta
    35041 tcctagaaaa tccagttatc caaggccaaa atgctggtgc aggttgtacc tttgcctcta
    35101 gcattgccag tcacttgatt aaaggtgata aacttttgcc agcagtagaa agctctaagg
    35161 ctttcgttta tcgtgctatt gcacaagcag atcagtatgg agtaagacaa tatgaagcaa
    35221 acaaaaacaa ctaaaatcgc ccttgtatcc ctattaaccg ccctttctgt ggttctaggt
    35281 tatttcttaa aaatcccaac acctacagga attctaactc ttttagatgc tggtgtcttc
    35341 tttgcggcct tttactttgg tagtcgtgaa ggagcggtag tcggaggact agcaagtttc
    35401 ttgattgacc tcttatcagg ctaccctcag tggatgttct ttagcttggt caaccatggc
    35461 ttgcagggat ttttcgcagg atttaaagga aaaagtcagt ggttaggcct tattttagca
    35521 actattgcca tggtaggagg ctacgccttg ggttctactt tgatgaatgg ctgggcagca
    35581 gccctcccag aaattctacc aaatttcatg caaaatatgg tagggatgat tgtaggattt
    35641 attcttagtc aaagtatcaa gaagattaag taatactctt cgaaaatctc ttcaaaccac
    35701 gtcagcttcc atctgcaacc tcaaaacact gttttgagca gcctgaggct agctttctag
    35761 tttgcacttt gattttcatt gagtataaag aggttgagta aaaagtattt caaataagaa
    35821 aaacgcatag tatcaggtgt tgaatgaact gccccccaaa agttagacag aaaaaatcta
    35881 acttttgggg tgttttatta tgaaactaac ttatgatgat aaagttcaga tctatgaact
    35941 tagaaaacaa ggatatagct tagagaagct ttcaaataaa tttgggataa acaattctaa
    36001 tcttaggtac atgattaaat tgattgatcg ttacggaata gagttcgtca aaaaagggaa
    36061 aaatcgttac tattctcctg atttaaaaca agaaatgatt cataaagtct gacatgaagg
    36121 ctagactaaa gatagagttt ctcttgaata cggtctccca agtcgtacga tacttcttaa
    36181 ctggctagca caatacagga aaaacgggta tactattgtt gagaaaacaa gagggagagt
    36241 acctaaaatg ggacgtaagc caaaaaagag acctgaagag aggacagaat tagaacgtct
    36301 tcaagcagaa aatgagtacc tgagagcgga gaatgccatc ctaaaaaagt taagagaact
    36361 ccgattgaag gaggaaaaag agaaagacag aaattgttta agaattaatg actgagtttt
    36421 cgttagatct tcttctaaaa gccattaaac tagctcgttc gacctactac tatcacttga
    36481 aacagctaga caaaacagat aaggaccaag agcttaaagc tgaaattcaa tccattttta
    36541 tcgaacacaa gggaaattat gcttatcgtc gaattcattt agaactaaga aatcgtggtt
    36601 atctggtaaa tcataaaaga gttcaaggct tgatgaaagt actcaattta caagctaaaa
    36661 tgcgacagaa acgaaaatat tcttctcata aaggagacgt tggtaagaaa gcagagaatc
    36721 tcattcaagg ccaatttgaa ggctctaaaa caatggaaca gtgctacaca gatgtgactg
    36781 aatttgccat tccagcaagt actcaaaagc tttacttatc accagtttta gatggcttta
    36841 atagcgaaat tatcgcctat aatctttcaa cttcacccaa cttagaacaa gtacaaacaa
    36901 tgttggaaca ggcattcaca gagaagcact acgagaatac gattctccat agtgaccaag
    36961 gctggcaata tcaacacgat tcttatcatc agtttcttga gggtaaggga attcaagcat
    37021 ccatgtcacg caagggaaac agccaagaca acggtatgat ggagtccttc tttgggattc
    37081 tgaaatcgga aatgttttac ggttatgaga agtcgtttca gtcgcttaag caattggaac
    37141 aagctattgt agactatatt gattactaca acaataaacg aattaaggta aaactaaaag
    37201 gacttagtcc tgtgcaatac agaactaaat ccttcggata aattaattgt ctaactgttt
    37261 gggggcagta cattttaaca cttgatacta tgcgttttat tgtgggaaga ttttcctcat
    37321 tttctagtga aattgaactt tttctaacat cttttgatag atgacttctt aatcaattat
    37381 catttccatt gttgtttctt ggggtttcat cccttgtctt tgataaaagc ggagagcacc
    37441 ctcgttatca ttccagacac ttagggttag attattgcag ccaatttctt tagcataata
    37501 gcagaaaaat gacaataaaa tagcccctag atattttgaa aggaaagcat aggggctata
    37561 tagtttaatc aaaataaagc aaatctttgc tggtgcttgt aaagaggtcg aagccatcct
    37621 tggtaacaac accgcagtct tcaatacgaa caccgacttt accagggata tagatacctg
    37681 gttcaacaga gaagcacatg ccttcttcga tgaccatgtc gtttccttcc atgatagatg
    37741 ggaattcatg gacatccata ccgataccat gcccgagacg gtggttgaag tactcaccat
    37801 aaccagcttt ttcgatgacc tcacgggcag cgcggtccac ttcatgagca gtcacacctg
    37861 gcttgataaa gtcaagagca gcttgttggg cttcaagagt caagttgtaa atatctttct
    37921 tgaattggtc tggtttgccg acagcgactg tacgagtcat atctgacgca tagccattga
    37981 ccagaacacc caggtcaaag aggagaagag catcattttc aaccttatta gctgctggaa
    38041 tgccgtgtgg attcgcagca ttatcaccag tcaagaccat ggtatcaaag ctcatttcat
    38101 aaccttcacg tttcatggca aagtcgattt gtgcgatgat atctgtctca gtcttatcaa
    38161 gagaaatatt gtcaaaacca acatgaacag ccttgtcagc ataaagacct gcaaccatca
    38221 ttttttgcac ttcatcagct gatttgatga ggcgcatgcg ttggatacga ggagtgaggt
    38281 tgtcaaactc agcagtctca aaaactgttt tcaaaccatg gtatttggtc aagatgagat
    38341 tgtcaaactc aacagcgaca cgtttgaagt caagttgtgg aagagcatgt ttgatttttt
    38401 gccatggatt ttcagaatcg acatagccca ctactgggaa ggaaacggtg ctacttgcac
    38461 gttctacttc aagagctggg acaaagagga gaggttcctg atccgctagg acaaagagga
    38521 acatttggcg ttcatgggga tcactgtaaa aaccagtgag gtaattgatt gtgacggggt
    38581 cagatacgac agcgacgtct agtttttctg attcaagata tgttaggatt tgttgtaatt
    38641 tagacatatg ctaccttctt tctacccctc tattttggca aaaaatgaga gaaaatgcaa
    38701 gggagaaggg taaaagaaaa gacaaaaaac tccgacaaga taacggagtt ctttgatatc
    38761 attttccttt gtttaagaaa agtcagcctt gcttttgacg tcactgtact cttcagcgat
    38821 ttcttggctg agaatgtcct cataggcagg gagttggatg tcctgaccat atttcttctt
    38881 gagggcagta gtaactaggc gataagccag attggcatta cgagagagga taggcccgtg
    38941 gaagtaggaa ccaaagacat tcttataatg aaccccttca ccgacctttt cttcgttgtt
    39001 tccatttcca tagacaacct gtcccagcgg tttttggtca tcagagagga aggtacgacc
    39061 ttggtgattt tcaaatccat agtaggtttc atcgaaatct tcattgtgaa tcttgatgtc
    39121 accgataaaa cggttattgg tctggttgag cgtgtagtgt cccatgaccc ctagcccttc
    39181 gatacgtttt cctgaagctt caacataata ttgacccaat agttggaaac caccgcagat
    39241 agccagaact acaccgtcgt tttggatgta gttgtcaatg ctctcttttt tagcaggtag
    39301 gtcgtctgca atgatacttt gttcaaagtc ttgaccacca ccgaaaaagg cgatgtcgta
    39361 gtgattttca tcaaagtcat catggagaga aacgatgtca acggtcacat gggctcccag
    39421 tttttcagcc acatacttga gcatgaggat gtttccattg tccccgtagg tattcatgag
    39481 atttccgtag aggtgggcaa tgttgagctg ataggggtaa ttgctatctt ttgaggaaag
    39541 tgaagtataa accattagtt catctccttt ctaacaatct gacgactagc cagcagttca
    39601 cgaaattcca gcatggcagt ataagttgcc agaatatagg catgcttgca gtcttgattc
    39661 tcaatggtct tgagaacttg ctccagatta ctcgtttcag tgattttctc agctggatag
    39721 ccagtcactc ggaggcgacg agcgatttca gaatgacgaa caccgccagc gttgatttca
    39781 ggaatgtcca tgtcagtgat ttgctcaaag tctgcatccc agatccagct agtgtcaatt
    39841 ccatctgcat agttggcatt aaggaggaca gataggctaa atggataagg tgctagtttg
    39901 atcatttcga tagcttgggt tgcaccgact ggatttttaa tcaagacaag ggtacattcc
    39961 ttgtcaccga tatgaaaggt ttcttggcgt ccaaagacag cacggctctt gtcaaatccc
    40021 tgtttgatga gttgggaatc tgcgccgagg aaacgggcga tggccacagc agctagggcg
    40081 ttatagatat tatagagccc gccgatttgg ataccgtatt cttggccgtc tatgacaaag
    40141 cgagagcgat tgttggtcaa ctcaaccagt tttgtcaaac gatagtcgag atcaggacgt
    40201 ttacatccac aaccttcaca gatataggca cccaagtttg cataggtatt atgctcatat
    40261 ttgaggatgc cttggcagtc aggacagaga atcccttcgg tattgtagtg agcaagttgg
    40321 gctggtcctt tttccaagtc aaaaccaaaa tactctatag ggtttggaat agttggcttg
    40381 tagaaaagtg gactgtctcc gttaaggaga acagtagcag ttggaacttt tcgaatggca
    40441 tccaatatca tgttataggt agtatagatt tcaccgaaac ggtccatctg gtcacggaag
    40501 atattagtaa tgacaaaaag actaggctgg atatagtcac agatacgaga tagactggct
    40561 tcgtcaattt cgaggacggc aatatttttc ccagtttttg aagatttggc tgttaggaag
    40621 gttgttgcaa tccctgtaat catgttggca ccgcttgggt tggttagaac ttgaccataa
    40681 acctctttta aaatgccgac agtgagggca gttgtcaggg tttttccatt tgttccagtg
    40741 acaacgacaa tctcgtagtt cttagctagg ctttgtaaaa tatctttatc aaattgaagg
    40801 gcgactttcc ctgggagcgt acttccacgt ccaagacggc ttaaaacgaa gtgggaagaa
    40861 cgcccagcaa gaaggcccaa agtagttttt aagttcatgt ttctattata tcacaaaaga
    40921 gggaaaagac agatttggtg tttcgtagaa gtaaaaacag cccaaagagg gctgtcagtt
    40981 aagatgagat ttcaacttaa atcgcaaaca agtcattcaa gttctcagcc aaggttgggt
    41041 gagtgaagat ttgttttgtg aagtaagtgt aaggaatctt gttgtccata gcaacagtaa
    41101 tgatgttgat gatttcttga gaaccttctg agaagatgct tgcaccaaga atttcttttg
    41161 tttcagtatt aacaacagct ttgaaagctc cgcgaaggtc tccatttacg tgaccacgag
    41221 gcatggctgc aacagggatt tctttcactg cgtatggaag tttcaaatca gctgcttggc
    41281 tttcagtcaa accaacttgt gaaagtgcag gtgtgatgaa catagtattt ggcacattga
    41341 gacggtcctc aagtgtgtag ctgccatctc cagcaaggta gctgtaaaca acacggaagt
    41401 catcaagtga aatgtaagta aattgaaggc caccgttgac atctccaact gcaaagacac
    41461 caggaacgtt tgtttgacag tgtttgtcta ctttaatagc accacgttca gttagttcaa
    41521 tatctgtatt ttcaagttga agtggttcta catttggttt gcgtccagtt gcgtagagaa
    41581 gggcgtcgaa acggtaagtt tcgtcttcag ttacgacaag cacttggtca ccatcgtttt
    41641 tgatttcagt agtatggata ttttgaagca attcaatgcc atcttcttcc atgtattgtt
    41701 tagcaagagc tgcgatggaa ggttctgcac gaggtaggaa tgtatccaag gcatctagga
    41761 ctgtgacctt gcttccaagt ttgttgtaaa ggccggcaaa ttcaagaccg atatttccgc
    41821 caccaaggat tccaagtttt tcaggtaatt tgtccaagct ttggatacct gttgagtcaa
    41881 agatgttttt gcttgtagca agtccaggaa ttggcaagac gtttgaaaca gcaccagtgt
    41941 tgatgacgat tgtttcagca gtcagttctt tcttttcatc accagcttgg atttcgatga
    42001 ctttatttga aaggaagtga gcttccgcat caaagatatc tacgcctgta ccagcaacag
    42061 tcgcatagtt tttaccgttg aggcgaccag tgatcgtgtt tttagtagca atcacttctt
    42121 caaaagacaa gtccttttca gcagcaacta gcaaggtttt agttgggata caaccaatgt
    42181 tgatacaagt tccaccgtac atagccttgc tgcgttcaac gagggcaact tttttgccag
    42241 ctgaagccaa tttacctgct agtgttttac cagctttacc aaatccaata acaattaaat
    42301 cgtatgttaa catttatctt cctcctattc gaatttcatt ctagcacaag aaaaaaactt
    42361 ttgcacaatt ctgctacgga aaagacagaa aaagataaaa acgctttcca gacaaaaaac
    42421 tagtaatttt ttgacaagct tgataaacta aaatcctatc tatttttata taagaaagaa
    42481 taaatgttcg aaaataggag gttttatgaa atcgaatcgt tatattattg cctttgctgg
    42541 ggtcatttta cacttaatgc tgggttcgac ttatgcttgg agtgtttatc gtaaccctat
    42601 tattgaaaaa acgggatggg atcaggcttc tgttgccttc gcctttagtc tagcaatctt
    42661 ttgtttgggc ttatcggctg catttatggg gcgtttggta gaaaaatttg gtccgaaagt
    42721 catggggagt ctatctgctt ttctatacgc aggtggaaat atcttaacag gatttgcaat
    42781 agaccgtcag gaactgtggt tgttgtatct agcttatggc attttaggtg ggcttggttt
    42841 gggagcaggc tatattaccc ctgtgtcaac gattataaaa tggtttcctg ataaacgtgg
    42901 tctcgcaaca ggtttagcga ttatggggtt tggttttgct tctttattga ctagtcccat
    42961 agcgcaacac ctcatcgcag gggtagggat tgtagaaact ttttatattt taggagcaag
    43021 ttactttatt atcatgctcc tagcttcaca attcattaag cgtccaaatg agcaagagct
    43081 tgcaatttta tcttcttcag ggaaagaaaa aacagcctct ttgacgcaag gaatggctgc
    43141 aaatcaggct ctaaaaagca atcggtttta tatgctttgg attattttct ttatcaacat
    43201 agcttgtggt ttaggcttaa tttcagcggc atcgccaatg gcacaggaga tggctggctt
    43261 gtctacaagt catgcagcag taatggtggg tgttttgggg attttcaatg gatttggtcg
    43321 cttgctctgg gcgagtttgt ctgactatat cggtcgccct ctaaccttta gtatattact
    43381 gcttgtcaat cttttctttt ctctctcact ttggctcttt acagattccg ttttatttgt
    43441 agttgctatg tctattttga tgacttgcta tggagctggt ttttctttga ttccagctta
    43501 tctcagtgat atttttggaa ccaaggaatt ggccgctctg catggttata ttttaacagc
    43561 ttgggcaatg gctggtttag cgggacctat tttattagca gagacttata aaatggctca
    43621 ttcgtacaca caaaccttgt tcgtttttct cattttatac agtatcgcct tggctttgtc
    43681 ttattatcta ggtcgttcaa tcaaaaaaga aagtcaaaaa ccgcttacat gattttctgt
    43741 agaaatgggg ctatcttttg ctctggtctt gtgttatact agataggttg caaagaaaac
    43801 agtacttttc ttttgtggaa aagaagcaac acgattttat atctagttat atgaaaatac
    43861 gtcataaaaa gaaaagtata aactaagccc tatagggtgg cttcgcacca cctttagaaa
    43921 gaagaataac gtgaaattta atgaattaaa cttgtctgct gatttgctag cagaaattga
    43981 aaaagctggt tttgtagaag ctagtcctat ccaagaacaa actattcctt tggcccttga
    44041 aggcaaggat gttatcggtc aagctcagac tggtacagga aaaactgcag cctttggctt
    44101 gcctaccctt gaaaaaatcc gtatagaaga agcgactatt caagccttgg tcatcgctcc
    44161 aactcgtgaa ctagctgtcc aaagtcaaga agaactcttc cgctttggtc gtagtaaggg
    44221 agtcaaagtc cgttcagtat atggcggatc aagcattgaa aaacaaatta aggctcttaa
    44281 atctggtgcc catatcgtgg tgggaactcc aggtcgcctc ttggacttga ttaaacgcaa
    44341 ggccttgaaa ttacaagaca ttgaaaccct tatccttgac gaagcggatg aaatgcttaa
    44401 catgggcttc cttgaagaca tcgaagccat tatttcccgt gtacctgaga accgtcaaac
    44461 tttgcttttc tcagcaacta tgccagatgc catcaaacgt atcggtgttc agtttatgaa
    44521 agcccctgaa catgtcaaga ttgcggctaa ggaattgaca acagaattgg ttgaccagta
    44581 ctatatccgt gttaaggaac aagaaaaatt tgacaccatg actcgtctca tggatgtggc
    44641 acaaccagaa ctcgctattg tatttggtcg taccaaacgc cgtgtggatg aattgactcg
    44701 tggtttgaaa attcgtggct tccgtgcaga aggaattcat ggcgacctag accaaaacaa
    44761 acgtcttcgt gtccttcgtg actttaaaaa tggcaatctt gatgttttgg ttgcgacaga
    44821 cgttgcagcg cgtggtttgg atatttcagg tgtgacccat gtctacaact acgatattcc
    44881 acaagatcct gagagttatg ttcaccgtat cggtcgtaca ggtcgtgctg gtaagtcagg
    44941 tcaatctatt acttttgttg ctccaaacga aatgggttac cttcaaatca ttgaaaactt
    45001 gactaagaaa cgcatgaaag gtctcaaacc tgcaagtgta gaagaatcct tccaatcaaa
    45061 aaaacaggta gctctcaaga aaatcgaacg tgattttgca gatgaaacca ttcgtgccaa
    45121 ctttgagaaa tttggtaagg atgctcgcaa attggctgct gagtttactc cagaagaatt
    45181 ggcaatgtat atcttgagtc tgacagtcca agacccagat agccttccag aagtggagat
    45241 tgcacgtgaa aaaccactac cgtttaaacc atcaggtaat ggtttcggtg gtaaagctaa
    45301 gggaggtcgt ggaggccgtc gtggggacga ccgtcgagag cgtgatcgtc gtggcaatgg
    45361 tcgccgtgat gagttcaaaa aaggaagtcg tggcaacgat cgttttgata aggaaaaacg
    45421 ttaccgtaag gataataaaa aaccacgcaa tactttaagc gaaaagcaaa caggctttgt
    45481 tattcgtaac aaaggtgata aataagaaaa agcggttcaa aatgaatcgc ttttttatat
    45541 aaggagaccg aatgtgaaaa agacaaataa aattattata ttatctttta taatattatg
    45601 atacacaaaa ataggcgact tgtcaataga aaaggaacaa tttaattaaa aatattctgg
    45661 tttttaatta aattgtaagt caatgcaagt caataaggaa ttttcagata attattgaaa
    45721 aagagacgtt tttatgttat aatgatagcg attaaattcg aggtgaaaaa tggcacattt
    45781 attagaaaaa actagaaaaa ttacatcaat tttgaaacgc tcagaggagc agttgcagga
    45841 tgagctccct tacaacgcta ttacgcgtca gttagcggat attattcatt gcaatgcctg
    45901 cattatcaat agtaagggac gtctgcttgg ctattttatg cgttataaaa caaatacaga
    45961 tcgcgtagag caattcttcc aaactaagat tttcccagat gactacgttc aaggggctaa
    46021 tatgatttac gaaacagaag caaacttgcc tgttgagcat gatatgagta ttttccctgt
    46081 tgagagtaga gatgattttc cagatggctt gacgactatt gcaccgattc atgtatcggg
    46141 gattcgcctt ggttctttga ttatttggcg taatgataaa aaattcgaag atgaggactt
    46201 ggttcttgtt gagattgcca gtaccgttgt tgggattcag cttcttaact tccaacgtga
    46261 agaagatgag aaaaatattc gtcgtcgtac tgctgtcacc atggcggtca ataccctttc
    46321 ttactccgaa ctccgtgctg tttcagcaat tttaggggaa ttaaatggaa atgaagggaa
    46381 gttgactgcg tcagtgattg cagatcgtat cggaatcact cgctctgtga ttgtcaatgc
    46441 tcttcgtaaa cttgagtctg cggggattat tgaaagtcgc tcacttggaa tgaagggaac
    46501 ctatcttaag gtcttgattt cagatatttt tgaagaagtg aagaaaagag attactaatg
    46561 acaaaggctt taatttcgat tgattataca gaagattttg ttgctgatag tgggaagctg
    46621 acagcaggtg ctccagctca ggcgatttcg gatgccatca gcaaggtaac tcgattagct
    46681 tttgaacgag gagattatat cttctttact attgatgctc atgaagaaaa cgattgtttc
    46741 catccggaaa gtaagttatt tcctcctcat aatctgattg ggacgagtgg acggaattta
    46801 tatggagatt tggggatctt ttatcaagag catggttcag acagtcgtgt cttttggatg
    46861 gataaacgcc attactcagc tttttcaggg actgacctag atattcgttt gagagagcgt
    46921 agagtgtcta ccgttatctt aacaggtgtc ttgacggata tctgtgtcct acatacagct
    46981 atagatgcct ataatctagg atatgacatc gagattgtta aaccagctgt tgcttccatc
    47041 tggcctgaaa atcatcaatt tgccctaggt catttcaaaa atacactcgg agctaagtta
    47101 gtagatgaaa atctaaatga actttctgag taacctggtt ggtgaaaatg aaaaaatttg
    47161 aaaaaaagtg ttgacaagca tcccaaaagt tgatatacta gtaaagtaat cgatgcgggg
    47221 atggcggaat tggcagacgc gcaggactaa ggatcctgtg accgctttag gtcgtgaggg
    47281 ttcaagtccc tctctccgca taggaaaaga gttagctaaa gctagctctt ttgtatttct
    47341 ctaaaaaatt agaatccagt caaatgtagt ggagaatcag cgaaaatatg ggaaaactga
    47401 tccttgtttc tgcttttgtc atagaagaat aataaagatt atcttcttca aattctccga
    47461 tattctctaa agttttgtgc aagttgcaca gaactttttt atttttttgg tcatcttgcc
    47521 atagaaatat aaagcgtttt catctataat ataattatca aaagacaaaa ggagttcacc
    47581 tcatggtaga attgaatctt aaaaatattt acaaaaaata tccaaacagc gaacactatt
    47641 cagttgaaga tttcaacttg aacatcaaag ataaagaatt tatcgttttc gtaggacctt
    47701 caggatgtgg taaatcaact acactccgta tgattgctgg tcttgaagac atcacagaag
    47761 gtactgcatc tatcgatggc gtggttgtca acgacgtagc tccaaaagac cgtgatatcg
    47821 ccatggtatt ccaaaactac gctctttacc cacacatgac tgtttatgac aacatggctt
    47881 tcggtttgaa attgcgtaaa tacagcaaag aagacattaa caaacgtgtt caagaagcag
    47941 ctgaaatact tggattgaaa gaattcttgg aacgtaaacc ggctgacctt tcaggtggtc
    48001 aacgtcaacg tgttgccatg gggcgtgcga ttgtccgtga tgcgaaagta ttcttgatgg
    48061 acgaaccttt gtcaaacttg gatgccaaac ttcgtgtatc aatgcgtgct gaaatcgcta
    48121 aaattcaccg tcgtatcgga gctacaacta tctatgtaac tcacgaccaa acagaagcga
    48181 tgacacttgc agaccgtatc gttattatgt cagctactaa gaaccctgct ggtacaggta
    48241 ctatcggacg tgtagaacaa atcggtactc ctcaagaagt ttacaaaaat ccagttaaca
    48301 aattcgttgc aggattcatc ggaagcccag ctatgaactt catcaacgtg aaattggttg
    48361 gtagcgaaat tgtttctgac ggtttccgtt tgaaagtgcc agaaggagca ttgaaagttc
    48421 ttcgtgaaaa aggctacgaa ggaaaagaat tgatctttgg tatccgtcca gaagacgtga
    48481 atgcagaacc tgctttcctt gaaacattcc cagactgtgt tgtaaaagcg actatctctg
    48541 tatcagaact gcttggttca gaatctcacc tttactgcca agttggtaaa gacgagtttg
    48601 ttgcaaaagt tgatgctcgt gactacttgc aaacaggtgc aacagttgag cttggatttg
    48661 acttgaacaa agcacacttc ttcgatgtag aaactgaaaa aacaatctac taagaataaa
    48721 taaaattcaa agcactacaa gaaaagatat ctctttatca attgtagtgg agagatatca
    48781 gttaatctag ggagagaaac aaaatgcttc tctccttttt gctagggaag tcatattata
    48841 catctatatt gtgatgctct ttatactctt cgaaaatctc ttcaaaccac gtcaacgtcg
    48901 ccttgccgta cgtatgatta ctgacttcgt cagttttatc tgcaacctca aagctgtact
    48961 ttgagtagct tacggctagt ttcctagttt gctctttgat ttccattgag tattatttgt
    49021 gggtaccatc tacaagtgaa gctatatgcg taaactacgt gagcaattga attcgaacta
    49081 gagaggtaat aataaattta tgctatagtt atggtgactt gtatgctttt gattctagtt
    49141 tatcaaataa tagattagaa ttgtcagata atatcatttt gtgttataat gaagaaaaaa
    49201 cagaggtgtt caaatgtcag aagcaggtca taagttttta gcaaaattgg ggaaaaaacg
    49261 cttacgtcca ggtggaaagc gtgccacaga ttggttaatt gcagaaggag gattttcaaa
    49321 agaaaagaga atactagagg ttgcgtgtaa taggggaact acagcaattg agttggcaca
    49381 gcgttttggt tgcaagataa ctgctgttga tatggatgct caagctttag aagtggctaa
    49441 aaaatctgct ggaacggcag gtgttgctca tttaatcagt tttgaaagag caaatgcaat
    49501 gaaacttcct tatcaagatg ctagttttga tattgttata aatgaagcta tgctgactat
    49561 gcaagccgat caagctaaga aaaaatgtgt aatggaatat ctaagggtat taaaacctgg
    49621 aggtcttctc ttgacacatg atgtgcttct taaggaagct aaagagtcta tcagacagga
    49681 attatcacaa gcaattcatg taaatgtagg tcctttaact caagatggtt gggaacaggt
    49741 gatgatagaa tcaggttatt gtgatgtgaa agcattgact ggtgaaatga cattaatgaa
    49801 attatcgggt atgatttatg acgaaggttt gctaggaact ttgaaaattt gtgtaaatgc
    49861 ttgtaaaaag gagaatagaa agcagttttt aactatgtat aaaatgtttg ctaagaataa
    49921 acagaaattg ggctttattg cgatggctag ttataaatcg tcaaaacgtt agataattat
    49981 tgaagttaac ttttcctttt ttctttctta aaaaatatgc tataatagag agtaaaaaac
    50041 tttgaaagaa agaaaaaaga tgaatttaaa agattacatt gcaacaattg aaaattatcc
    50101 aaaggaaggc attaccttcc gtgatattag tcctttgatg gctgatggaa atgcttatag
    50161 ctacgctgtt cgtgaaatcg ttcagtatgc tactgacaag aaagtcgaca tgatcgtggg
    50221 acctgaagct cgtggattta tcgtgggttg tccagttgcc tttgagttgg gaattggttt
    50281 tgcgcctgtt cgtaagccag gtaaattgcc acgcgaagtt atttctgctg actatgaaaa
    50341 agagtacggt gtcgatacct tgactatgca cgcggatgcc attaagccag gtcaacgtgt
    50401 tcttattgta gatgaccttt tggcgacagg tggaactgtt aaggcaacta tcgagatgat
    50461 tgaaaaactt ggtggtgtta tggcaggttg tgccttcctt gttgaattgg atgaattgaa
    50521 cggccgtgaa aaaatcggtg actacgacta caaagttctt atgcattatt aatgaaaaca
    50581 gtccctaggg ctgttttctc tacactagga tataaaaata gactataact agttagagaa
    50641 aaactataat tgaaaactat atcttcttgc agtataataa aaggactaag tgtttgagat
    50701 ttgtcttcaa acacatgcaa ttattcctga gagagtacag ttaggagagg gttatgccga
    50761 ttcgaattga taaaaaattg ccagctgttg agattttacg gacagagaat atctttgtca
    50821 tggatgatca acgtgctgcc caccaagata tccgtccttt gaagatttta attttaaatc
    50881 tcatgccaca gaaaatggtc acagagaccc agttgttgcg ccacttggct aatacacccc
    50941 tacaactgga tattgatttt ctctatatgg agagccaccg ttctaaaaca actcgttcag
    51001 agcacatgga gaccttctat aaaacttttc ctgaagtcaa ggatgagtat tttgatggga
    51061 tgatcatcac gggtgctcca gttgagcatt taccatttga ggaagtggac tattgggagg
    51121 aatttagaca gatgcttgag tggtctaaga ctcatgtcta ttcgaccctt catatctgtt
    51181 ggggagctca ggctgggctt tatctgcgct atggtgtaga aaaataccag atggacagta
    51241 agctatcagg tatttatcct caggacaccc taaaagaggg tcaccttcta tttagaggct
    51301 ttgatgatag ctatgtatcc cctcattcac ggcacacgga gatttctaag gaagaggtct
    51361 taaacaagac taatctcgag attttatcag aaggacctca ggttggggtt tctattttgg
    51421 ccagtcgtga tttacgagaa atttatagtt ttggtcattt ggagtatgac cgtgatacct
    51481 tggcaaaaga gtattttcga gatcgtgatg caggtttcga cccacatatt ccagaaaatt
    51541 actttaaaga tgatgatgtt aatcaggtac cttgtctttg ttggtcttca tctgcagccc
    51601 tctttttcag taattgggta aaccatgcgg tctatcagga gacgcctttt gactggagaa
    51661 agatagaaga tgatgcatct gcatatgggt atttataaga ggaattatga catatttaga
    51721 cgcttttaaa tcaggtacct tggttttacc gagtgccctg ctcttgcatt ttaaggaact
    51781 ctttccttct agcgacgatt ttctggtttg gcaatttttc tatttgcaaa atacgacagg
    51841 cttagaagaa atgtcgccaa gccagattgc tgaaaggatt ggcaaggaaa tttcggatgt
    51901 caaccagtcc atttctaatc tgacggaaag gggactgctc cagtatcgta ctatcgaatt
    51961 aaatggcgaa attgaattgc tctttgatgc tagtttggcc ttggaacgtt tggatgacct
    52021 gtttggagca gttcattcaa gttcagacca gctaacacca caaaaccagc tcaaggattt
    52081 ggtggaaacc ttccagcagg agttgggacg attgttgacg ccttttgaga ttgaggattt
    52141 gaccaagaca ctaaaggaag atggaaccag tgctgacttg attaaggagg ctcttcgtga
    52201 agctgttttg aatggaaaac caaactggaa gtacattcag gcgattttga gaaactggcg
    52261 ccatgaagga atcaagagtg tggctcaaat tgaggccaag agagcagaaa gagaagcaag
    52321 caatcctcag ttgacacagg tatctgcaga tttcagaaat gccatggatc tctggaagga
    52381 ttaatccatg caagtaggct tgaaatccga gtaagatttg caagctgtgt ataattgtga
    52441 tagaataaat agaaaataaa ttgaaaaaag aggtatgtga aatgtcacgt aaaccattta
    52501 tcgctggtaa ctggaaaatg aacaaaaatc cagaagaagc taaagcattc gttgaagcag
    52561 ttgcatcaaa acttccttca tcagatcttg ttgaagcagg tatcgctgct ccagctcttg
    52621 atttgacaac tgttcttgct gttgcaaaag gctcaaacct taaagttgct gctcaaaact
    52681 gctactttga aaatgcaggt gctttcactg gtgaaactag cccacaagtt ttgaaagaaa
    52741 tcggtactga ctacgttgtt atcggtcact cagaacgccg tgactacttc catgaaactg
    52801 acgaagatat caacaaaaaa gcaaaagcaa tctttgcgaa cggtatgctt ccaatcatct
    52861 gttgtggtga atcacttgaa acttacgaag ctggtaaagc tgctgaattc gtaggtgctc
    52921 aagtatctgc tgcattggct ggattgactg ctgaacaagt tgctgcctca gttatcgctt
    52981 atgagccaat ctgggctatc ggtactggta aatcagcttc acaagacgat gcacaaaaaa
    53041 tgtgtaaagt tgttcgtgac gttgtagctg ctgactttgg tcaagaagtc gcagacaaag
    53101 ttcgtgttca atacggtggt tctgttaaac ctgaaaatgt tgcttcatac atggcttgcc
    53161 cagacgttga cggtgccctt gtaggtggtg cgtcacttga agctgaaagc ttcttagctt
    53221 tgcttgactt tgtaaaataa tcagtaagta gcaaaagcta ggtggaacag cattcagatg
    53281 tctgttacat tttttatagg agagcaaaga ttgaaaacaa aaattggatt agcaagtatc
    53341 tgtttactag gcttggcaac tagtcatgtc gctgcaaatg aaactgaagt agcaaaaact
    53401 tcgcaggata caacgacagc ttcaagtagt tcagagcaaa atcagtcttc taataaaacg
    53461 caaacgagcg cagaagtaca gactaatgct gctgcccact gggatgggga ttattatgta
    53521 aaggatgatg gttctaaagc tcaaagtgaa tggatttttg acaactacta taaggcttgg
    53581 ttttatatta attcagatgg tcgttactcg cagaatgaat ggcatggaaa ttactacctg
    53641 aaatcaggtg gatatatggc ccaaaacgag tggatctatg acagtaatta caagagttgg
    53701 ttttatctca agtcagatgg ggcttatgct catcaagaat ggcaattgat tggaaataag
    53761 tggtactact tcaagaagtg gggttacatg gctaaaagcc aatggcaagg aagttatttc
    53821 ttgaatggtc aaggagctat gatgcaaaat gaatggctct atgatccagc ctattctgct
    53881 tatttttatc taaaatccga tggaacttat gctaaccaag agtggcaaaa agtgggcggc
    53941 aaatggtact atttcaagaa gtggggctat atggctcgga atgagtggca aggcaactac
    54001 tatttgactg gaagtggtgc tatggcgact gacgaagtga ttatggatgg tgctcgctat
    54061 atctttgcgg cctctggtga gctcaaagaa aagaaagatt tgaatgtcgg ctgggttcac
    54121 agagatggta aacgctattt ctttaataat agagaagaac aagtgggaac cgaacatgct
    54181 aagaaaatca ttgatattag tgagcacaat ggtcgtatca atgattggaa aaaggttatt
    54241 gatgagaacg aggtggatgg tgtcattgtt cgtctaggtt atagcggtaa agaagacaag
    54301 gaattggcgc ataacattaa ggagttaaac cgtctgggaa ttccttatgg tgtctatctc
    54361 tatacctatg ctgaaaatga gaccgatgct gagaatgacg ctaaacagac cattgaactt
    54421 ataaagaaat acaatatgaa cctgtcttac cctatctatt atgatgttga gaactgggaa
    54481 tatgtaaata agagcaagag agctccaagt gatacagaca cttgggttaa aatcatcaac
    54541 aagtacatgg acacgatgaa gcaggcgggt tatcaaaatg tgtatgtcta tagctatcgt
    54601 agtttattac agacgcgttt aaaacaccca gatattttaa aacatgtaaa ctgggtagcg
    54661 gcttatacga atgctttaga atgggaaaac ccttattatt caggagaaaa aggttggcaa
    54721 tatacctctt ctgaatacat gaaaggaatc caagggcgcg tagatgtcag cgtttggtat
    54781 taagcgatga tttgaaagag ggatgtgata gtagcaccct ctttttcttt gttttatgat
    54841 agttcatcct cgagtaaatt caagatcttg ctcggaaatg aagcttatat agtagattga
    54901 atatagacaa ataccttgtg attggtaaaa cattttagaa attcatttac ctttcctaat
    54961 cgacttggtt tcatcttatt tcaatctatt atagtattgg ggaatttctt caaaccacat
    55021 cagcttggtc agttctacct gcgacctcaa aacttgtgct ttggtcaagc tgggtttagt
    55081 ttcctagttt gctgatggat ttccattgac tataagcatc caaccctctt tttgtcttct
    55141 aaagaattct taaattatca gtctattgca acttttctca tgtgggtcat ttggcttgca
    55201 attgtctttc cttagtagta tactgaggta gtaatcatta agaagtggtt acataaaaat
    55261 aatgaatgag gtaaaataaa atggtagaat tgaaaaaaga agcagcaaaa gatgtcgcaa
    55321 cattaacaaa agcagcgcca gtagcattgg caaaaacaaa ggaagttttg aatcaagcag
    55381 ttgctgattt gtatgtagct cacgttgctt tgcaccaagt gcactggtat atgcatggtc
    55441 gtggtttcct tgtatggcat ccaaaaatgg atgagtacat ggaagctctt gatggtcatt
    55501 tagatgaaat cagcgaacgc ttgatcacac ttggtggaag cccattctct actttgacag
    55561 agttccttca aaacagtgaa atcgaagaag aagctggtga ataccgtaat gttgaagaaa
    55621 gcttggaacg tgttctagct atttatcgct acctcatcac tcttttccaa aaagcgttgg
    55681 atgtgactga cgaagaaggc gatgatgtta caaacgatat ttttgttggt gctaaggctg
    55741 aacttgagaa aacagtttgg atgcttgccg cagaacttgg acaagcacct ggtttgtaag
    55801 aaacaagaca acatagataa atctgtagga aatttcttac agattttttc tattttgtaa
    55861 gctattccaa accagtcttt ttttgagttt tttgataaaa tagtactatc agtgaaaagg
    55921 atggaagcat gactaagaaa atcgtagcta tttgggccca ggatgaagag ggtgtgattg
    55981 gtaaggacaa tcgtctgcct tggcatttgc cagcagaatt gcagcacttt aaagaaacaa
    56041 ctctgaatca tgctatcttg atggggcggg taacctttga tggaatgggg cgtcgcttgc
    56101 ttccaaaacg ggagaccctg attttgacgc gtaatccgga agaaaagata gatggggttg
    56161 ctacttttca ggacgtccag tctgttcttg actggtatca ggctcaagaa aagaatctct
    56221 acattatcgg tgggaagcaa atttttcagg cttttgaagc ttaccttgat gaagtgattg
    56281 tcactcacat tcatgctcgg gtggaaggag atacctattt ccctgaagag cttgacttgt
    56341 ctctttttga gacagtttca agcaaatttt acgccaaaga tgagaagaat ccttatgatt
    56401 ttaccatcca ataccgcaag agaaaggaag tttaatggaa cggagtttat ttggtctatt
    56461 cacggctttt ctgtgtttca tctgctttct ggcaggagca caagcttttc gtaaaaagcg
    56521 ttacgggctt tctatcctcc tttggttaaa tgcctttacc aatctggtca atagtattca
    56581 tgctttttac atgaccttat tttagataga atgacagtat agaatggaag gaaatcatgt
    56641 ctacaaatag aaaaaatgat atgatggttt attgctcatt ttgtggcaaa aaccaagaag
    56701 aagtacaaaa aataattgct ggcaacaatg cttttatttg taatgaatgc gtggagttag
    56761 ctcaggaaat cattcgagaa gaattggttg aggaagtctt ggcagacttg tctgaggtgc
    56821 caaaaccaat tgaactcctc catatcttga accactatgt aattggtcaa gatcgtgcca
    56881 agcgtgcctt ggcagtggcg gtttataacc actacaaacg catcaatttc cacgatacac
    56941 gcgaagagtc agaagatgtg gatttgcaga agtcaaacat tttgatgatt ggcccaactg
    57001 gttcagggaa aactttcctt gcccagacct tggctaagag cttgaatgta ccttttgcta
    57061 ttgcggatgc gacagctctg acggaggctg gttatgtggg tgaggatgtg gaaaatatac
    57121 tcctcaaact cttgcaggtt gctgacttta acatcgaacg tgcagagcgt ggcattatct
    57181 atgtggatga aattgacaag attgccaaga agagtgagaa tgtgtctatc acacgtgatg
    57241 tttctggtga aggggtgcaa caagcccttc tcaagattat cgagggaact gttgctagcg
    57301 taccgcctca aggtggacgc aaacatccac aacaagagat gattcaagtg gatacaaaaa
    57361 atatcctctt catcgtgggt ggtgcttttg atggtattga agaaattgtc aaacaacgtc
    57421 tgggtgaaaa agtcatcgga tttggtcaaa acaataaggc gattgacgaa aacagctcat
    57481 acatgcaaga aatcatcgct gaagacattc aaaaatttgg tattatccct gagttgattg
    57541 gacgcttgcc tgtttttgcg gctcttgagc aattgaccgt tgatgacttg gttcgcatct
    57601 tgaaagagcc aagaaatgcc ttggtgaaac aataccaaac cttgctttct tatgatgatg
    57661 ttgagttgga atttgacgac gaagcccttc aagagattgc taataaagca atcgaacgga
    57721 agacaggggc gcgtggactt cgctccatca tcgaagaaac catgctagat gttatgtttg
    57781 aggtgccgag tcaggaaaat gtgaaattgg ttcgcatcac taaagaaact gtcgatggaa
    57841 cggataaacc gatcctagaa acagcctaga ggtgactatg gaacttaata cacacaatgc
    57901 tgaaatcttg ctcagtgcag ctaataagtc ccactatccg caggatgaac tgccagagat
    57961 tgccctagca gggcgttcaa atgttggtaa atccagcttt atcaacacta tgttgaaccg
    58021 taagaatctc gcccgtacat caggaaaacc tggtaaaacc cagctcctga acttttttaa
    58081 cattgatgac aagatgcgct ttgtggatgt gcctggttat ggctatgctc gtgtttctaa
    58141 aaaggaacgt gaaaagtggg ggtgcatgat tgaggagtac ttaacgactc gggaaaatct
    58201 ccgtgcggtt gtcagtctag ttgaccttcg tcatgccccg tcagcagatg atgtgcagat
    58261 gtacgaattt ctcaagtatt atgagattcc agtcatcatt gtggcgacca aggcggacaa
    58321 gattcctcgt ggtaaatgga acaagcatga atcagcaatc aaaaagaaat taaactttga
    58381 cccgagtgac gatttcatcc tcttttcatc tgtcagtaag gcagggatgg atgaggcttg
    58441 ggatgcaatc ttagaaaaat tgtgaggaaa agaaaatggc aaaaacaatt catacagata
    58501 aggccccaaa ggctatcgga ccctatgttc aaggaaaaat cgttggcaac cttttgtttg
    58561 ctagcggtca agttccccta tcccctgaaa ctggggaaat tgtaggagag aatatccaag
    58621 aacagacaga gcaagtcttg aaaaacatcg gtgctatttt ggcagaagca ggaacagact
    58681 ttgaccatgt tgtcaaaaca acttgcttct tgagcgatat gaacgacttt gttcctttta
    58741 atgaggttta ccaaacggcc ttcaaagagg aattcccagc tcgttcagct gtggaggtag
    58801 ctcgtcttcc tcgtgatgta aaagtcgaaa ttgaagtcat cgcagagatt ggataagcta
    58861 gttgaagttt ggtgttgcca aacttctttt gatataagga gaaaaagatg acaaagaaac
    58921 aacttcactt ggtgattgtg acagggatga gtggcgcagg gaaaactgta gccattcagt
    58981 ccttcgagga tctaggttat ttcaccattg ataatatgcc gccagctctc ttgcctaagt
    59041 ttttgcagct ggttgaaatt aaggaagaca atcctaagtt ggccttggta gtggatatgc
    59101 gtagccgttc tttcttttca gagattcaag ctgttttgga tgagttggaa aatcaagatg
    59161 gtttggattt caaaatcctc tttttggatg cggctgataa ggaattggtc gctcgttaca
    59221 aggaaaccag acggagtcac ccactagcag cagacggtcg tattttagat ggaatcaagt
    59281 tggaacgtga actcttggca cctttgaaaa atatgagcca aaatgtggtg gatacgactg
    59341 aactcactcc acgtgagctg cgtaaaaccc ttgcagagca gttttcagac caagaacaag
    59401 cccagtcttt ccgtatcgaa gtcatgtctt tcggatttaa atatggaatc ccgattgatg
    59461 cggacttggt ctttgatgtc cgtttcttgc caaatcccta ttatctacca gaactgagaa
    59521 accaaacggg tgtggatgaa cctgtttatg attatgtcat gaaccatcct gagtcagaag
    59581 acttttatca acatttattg gccttgattg agccgattct gccaagttac caaaaggaag
    59641 gtaagtccgt tttgaccatt gctatgggat gtacgggtgg acaacaccgt agtgtggcat
    59701 ttgctaaacg cttggtgcag gacttatcca agaattggtc tgttaatgaa gggcatcgcg
    59761 acaaagaccg cagaaaggaa acggtaaacc gttcatgaga aaaccaaaga taacggtgat
    59821 tggtggaggg actggaattc ccgtcattct aaaaagtctg cgggaaaaag atgtggaaat
    59881 cgcagctatc gtgacggtgg cagatgatgg tggttcttca ggtgaactcc gaaaaaatat
    59941 gcaacagttg acaccgccag gtgatcttcg taatgtcctt gtggccatgt cggatatgcc
    60001 taagttttat gagaaggtct ttcagtatcg gttctctgag gatgccggag cctttgctgg
    60061 ccatccattg ggaaatctca tcattgctgg cttgtcagaa atgcagggtt caacctataa
    60121 tgccatgcag ttattgagca aatttttcca tacaacaggg aaaatttatc cttccagtga
    60181 ccatcctttg acccttcatg cagtctttca ggatgggaca gaagtggctg gagagagtca
    60241 tattgtagac catcgaggca taattgacaa tgtctatgtg accaatgccc taaacgatga
    60301 tacgcctctg gccagccgtc gagtagtgca gaccatcctt gaaagtgaca tgattgtcct
    60361 agggccaggt tccctcttta cctctatttt gcccaatatc gtgattaagg aaattgggcg
    60421 ggctcttttg gaaactaagg cagaaattgc ctatgtctgc aatatcatga cccaacgtgg
    60481 ggagacggaa cactttacag atagcgacca cgtggaagtc ttgcatcgtc accttggtcg
    60541 cccttttatc gacactgtct tggtgaatat tgaaaaagtg cctcaggaat acatgaattc
    60601 caaccgtttt gatgaatact tagtgcaagt ggaacacgat tttgtaggtc tttgtaagca
    60661 agtttcgcgc gtgatttcat ctaacttcct tcgtctggaa aatggcggtg ccttccacga
    60721 tggagatttg attgtggacg agttgatgcg cattatacag gtgaaaaaat gagtttcaca
    60781 gtagcagtaa aagaagaaat cctgggccaa caccatctga gccggcatga attatctgcc
    60841 attatcaaaa tgtctggtag catcggtctc tcgacttcgg gcttgacttt gtcagttgtg
    60901 acagaaaatg ccaaactggc ccgtcacctc tatgagtcct ttctccattt ctatgaaatc
    60961 aaatctgaaa ttcgtcacca ccaacggagc aatcttcgca agaatcgcgt ctataccgtt
    61021 tttacagatg aaaaggtgca ggatttgtta agtgatttgc acttggcaga ctctttcttt
    61081 ggcctggaaa caggtattga tgaggcgatt ttatcggacg aggaagcagg tcgtgcctat
    61141 ctctgtggcg ctttcttggc aaatgggagc attcgtgacc ctgagtcagg caagtaccag
    61201 ttggaaatca gttctgttta tctggaccac gcgcaaggaa ttgcctccct tctccaacag
    61261 tttttactgg atgccaaggt gcttgagcgc aagaaggggg ctgtgaccta tctccagcga
    61321 gcagaagaca ttatggactt cttgatagta ataggagcca tgcaggcacg tgatgatttt
    61381 gagcgggtta agattttgcg agaaacccgt aacgacctca atcgggctaa taatgccgag
    61441 acagctaata tcgctcggac agtttctgcc agcatgaaga ccattaacaa tatcagtaaa
    61501 atcaaagata tcatgggctt agaaaatttg ccagtagatt tgcaggaagt ggcgcaactg
    61561 aggattcagc acccagacta ctctatccag cagttagcag atagtctcag cacccctctg
    61621 accaaaagtg gtgtcaatca cagactcaga aaaatcaata agatagcgga tgaattataa
    61681 aaccacgaat cctatgtgac tcgtggttct tttttataaa ctggtagagt gttttggttg
    61741 tactttttgt tcagggtcaa tgtagttgat agcgttgttg acagcagttg gagcttctcc
    61801 gaggcctgtc gcaatcagat caatttttcc gtcatagtag cagcagtcac cgatagcata
    61861 gatacctgct tggctggatt cctgtttgct gttgacgata atcttgtgac ggttgaggtc
    61921 gagcccccag tttttaaggt taccgacaga agatttgaaa ccatagttga caaagaggtg
    61981 gtctaggtca atggtttcag tttcatcaga tttgactttt gtgatttcaa gtttatcaag
    62041 tgtttttcca tttccaagga gttggctagg ggcgaatggt gtcttgatgg ttacagatga
    62101 ttcttgcaag gtttgaacac tgtgttccaa ggcacggaaa ttatctctgc ggtgaacaag
    62161 ggtagttggt gcgatttttt caaaagccaa agcccaatcc acagccgagt ctcccccacc
    62221 aagaatcgtc actttcttac cagcgtattg ctgaatgtta gaaacgtggt agtggatatt
    62281 ttcatagtcc tcaacccctt caagttccag cggacgtggt ttgaaggcac cgccacccat
    62341 agcgatgata actgttttag tcaggtgact tcctttggaa gttgtgatgg caaattcttc
    62401 ttcttgtttg tcaatctcaa gaaccgtttc attgagatga ataggggtat caaatccatt
    62461 tagctgttca atcaagcggt tagtcaactc ttctccagtc aggtttggga agcctggtac
    62521 gtctaggatt tccttttcag ggtagagaat agcaggttgt ccacctagct ggggaagaga
    62581 gtcgatgatt tgaaccttgg cttggcgtag gtgggcataa aaggctgcaa aaagcccgac
    62641 aggaccacca cccacaatgg taatatcata gagttgagac atagtttctc ctttgttttt
    62701 tctagtcagt ttattttatc atatttttgt tcaatgtaaa atggactagg atagggaaaa
    62761 aaatgccaga aaatggtata ataggacgaa agtgttttga tagggaggat atcagggatg
    62821 aattttcaac aattatccaa tctgcaatat tggaccagtt tgtttgcaag tccatggacg
    62881 atagctatca atctgattga tattttgatt gttgcttata ttttatacca ttttacaaaa
    62941 gctattgcag gaaccaagat tatgattttg gtacgtggag ttttggtgtt tattttagct
    63001 caaatccttg caaatatgat tggtttgact acgatttctt ggttaatcaa tcaaattatt
    63061 acttatgggg ttattgcggc ggttgttatc ttctctccag agattcggac tggtttggaa
    63121 cgtttgggaa gagcgacaga tttcttttcc aatgccccta ttagtgctga ggaacagatg
    63181 attcgtgcct ttgttaagtc tgttgaatac atgagtcctc gtaaaatcgg ggccttggtt
    63241 gctattcagc gtgtacgtac cttgcaggag tatatgtcga caggaattcc cttggatgct
    63301 aagatttctg cagaacttct cattaacatt tttattccca acactcccct acatgacggt
    63361 gcggtgatta tcaaagaaga acgtatcgct gtgacgtctg cctatctgcc cttgacaaaa
    63421 aacacaggga tttccaagga atttgggacc agacaccggg cggctatcgg tttatcagaa
    63481 gtctcagatg ccttgacttt tgtcgtatca gaggaaacgg gaggaatttc gataacctat
    63541 aatggaaggt ttaagcacaa cctaacactt gatgaatttg aaacagaatt acgtgaaatc
    63601 ttacttccaa aagaggaagt gggtcttagt tttaaagaac gattgctagg aggatggaaa
    63661 catgaaaaaa aatagtttat atatcatatc ctcactcttt tttgcttgtg tcttatttgt
    63721 ctatgctacg gcgacgaatt ttcaaaacag taccagtgct aggcaggtaa aaacggaaac
    63781 ctatactaat acagtaacca atgtccctat tgacatacgc tataatagtg ataagtattt
    63841 tattagcggt tttgcttcag aagtatcagt ggtcttgact ggtgcaaatc gcctatcgct
    63901 agctagtgaa atgcaagaaa gtacacgtaa attcaaggtt actgctgacc taacagatgc
    63961 cggtgttgga acgattgaag ttcctttgag cattgaagat ttacccaatg ggctgaccgc
    64021 tgtggcgact ccgcaaaaaa ttacagtcaa gattggtaag aaggctcaga aggataaggt
    64081 aaagattgta ccagagattg accctagtca aattgatagt cgggtacaaa ttgaaaatgt
    64141 catggtgtca gataaagaag tgtcgattac gagtgaccaa gagacattgg atagaattga
    64201 taagattatc gctgtcttgc caactagcga acgcataaca ggtaattaca gtggttcagt
    64261 acctttgcag gcaatcgatc gcaatggtgt tgtcttaccg gcagttatca ctccgtttga
    64321 tacaataatg aaggtgacta caaaaccagt agcaccaagt tcaagcacat caaattcaag
    64381 tacaagcagt tcatcggaga catcttcgtc aacgaaagca actagttcaa aaacgaatta
    64441 aaaatagaaa aggattttat aacaatgggt aaatattttg ggactgatgg agtccgtgga
    64501 gaagctaacc tagagctaac accagaatta gcctttaaac taggacgttt tggaggctat
    64561 gttcttagtc aacatgaaac ggaagcgccg aaagtctttg taggacgtga cacacgtatt
    64621 tcaggggaaa tgctggaatc ggccttggtg gcaggtctcc tttcagtagg gattcacgta
    64681 tacaaacttg gtgtccttgc aacaccagca gtagcttact tggttgaaac tgaaggagca
    64741 agtgccggtg tcatgatttc tgctagccac aacccagccc ttgataacgg aatcaagttc
    64801 tttggcggtg atggcttcaa actagatgat gaaaaagaag cagaaattga agccttgcta
    64861 gatgctgagg aagacactct tcctcgtcca agtgcagaag gcttaggaat tttggtagat
    64921 tatccagaag gcttgcgtaa gtatgaagga taccttgttt caactggaac tcctcttgat
    64981 ggaatgaagg ttgccttgga tacagctaat ggagcagctt ctaccagtgc ccgtcaaatc
    65041 tttgcagacc ttggtgccca attgacggtt atcggggaaa caccagacgg tcttaacatc
    65101 aaccttaatg ttggttcaac acatccagaa gcccttcaag aagtggtcaa agaaagtggg
    65161 tcagctattg gtttggcctt tgatggagac agtgaccgct tgattgctgt tgatgagaat
    65221 ggtgacatcg tcgatggtga caagattatg tacatcatcg gaaaatacct ttctgaaaaa
    65281 ggacaattgg ctcaaaatac aattgtgaca actgttatgt ctaaccttgg tttccacaag
    65341 gccttgaatc gcgaaggtat taacaaggca gttactgcag ttggtgaccg ctacgttgtt
    65401 gaagaaatga gaaaatcagg ttacaacctt ggtggtgaac agtctggtca cgttatcttg
    65461 atggattaca ataccacagg tgatggtcaa ttatcagcag ttcaattgac taaaatcatg
    65521 aaggaaactg gtaagagctt atcagagttg gcggcagaag taacgattta tccacaaaaa
    65581 ttagttaata tccgagtgga aaacgtcatg aaggaaaagg ccatggaagt gccagctatc
    65641 aaggccatca tcgagaagat ggaagaagaa atggcgggga acggccgtat ccttgttcgt
    65701 ccaagtggaa cagaacccct cttgcgtgtt atggcagaag cgcctacaac agaagaagta
    65761 gactactatg ttgataccat cacagatgta gttcgtgctg aaattgggat tgactaaatc
    65821 ctagaaaact agatgaaaat aaaaaattat ggtacaatag cttataatat tgtagccgat
    65881 ggagaaagac atgaatctta aacgtgaaca agaatttgtt agtcagtatc attttgatgc
    65941 gcgtaatttt gaatgggaaa atgaaaatgg agctcctgaa accaaggtgg atgtgaattt
    66001 ccaattgctc caacatgacc aagaaaatca agtgacttcc ttgattgtca tcttgagctt
    66061 tatgattgta tttgataagt ttgtcattag tggaacaatc tcacaagtaa accatatcga
    66121 tggccgtatt gtcaatgaac caaatgaatt gaaccaagaa gaggtggaaa ccttggctcg
    66181 tccatgtttg aacatgctca atcgtttgac ttacgaagtg actgaaattg cattagactt
    66241 accaggaatt aatttggagt tctaatatga aattagctgt tttcacagat tcctctgctt
    66301 atctcagtgc agagatcttg caaagagaag acttgtttgt cttggatatt cctgtcaata
    66361 ttgatggtga ggaatatgtc gaaggcatca atctgtctgc tgaggaattt taccaaaaaa
    66421 tggctcaggc ttctgaattg cctaagacca gtcaaccaag tattgccaag ttagatgaga
    66481 tcttaacttc gctcaaagaa caaggctata cacatgcctt ggggcttttc ctatcttctg
    66541 gaatttcagg tttttaccaa aatatccagt atatggtcga tgactatgag ggcttaacca
    66601 ttgctttccc agacactttg attacaagtg ctcccctagg catcatggtt gaaagtgtct
    66661 ttaattggcg tgatcagggc gatgattttg ccagcattca ggataagcta gccattcaaa
    66721 tcagccgtac gtcagccttt atcatggtag atgacttgga tcatttggta aaaggtggac
    66781 gcctttcaaa tggggctgcc attttgggca atttgcttag cattaagcca atcctttatt
    66841 ttaacgatca aggtgtgatt gaagtttacg aaaaagttcg tactgaaaag aaggccacca
    66901 agcgcttaat tgaaattatc aaggaaacaa cggcttcagg tcaataccgg gtcattgtca
    66961 ttcatgggaa tgctcctgaa aaggctgaag aattgcgtca gcacttgctt gattttggct
    67021 tgggttcgga tgtttcactt gctacatttg gtagtgtcat tggaacgcac ctaggagcag
    67081 gaagtattgc tctgggttat attccagtga tttagttggc gcttctaggc tagttaagat
    67141 gccttgtatc ttagaaattg aacacggact acctgcctct tgaaaaaaga tgcctgtctt
    67201 gcctttcgtg gaaagtcagt gccattccct atttttcaga ggcagctaag gtcctttgta
    67261 tcttgataat tgaacacgcc tggaaccctg tgtgaaaaag atagttcttc caagaagtag
    67321 acacttcttg attggaattc ctattttcac tttgtgttct tacggacttt gtatcttaga
    67381 caggagtaga gatgagtatt cgagtaatta ttgccggttt taagggaaag atgggccagg
    67441 ctgcttgtca gatggtattg actgatccag acttggactt ggtggcagtt ttggatcctt
    67501 ttgagtctga gtcagaatgg cagggtattc ctgttttcaa ggataaggct gatttagctg
    67561 gttttgaagc ggatgtctgg gtagatttta ctactccagc tgttgcctac gaaaatacac
    67621 gttttgctct tgaaaatggc tttgctccag tagttggaac gactggtttc acgagtgaag
    67681 aaattgcaga gctaaaagaa ttttctcgtg cccaagactt gggtggcctg attgccccta
    67741 actttgcctt gggtgctgtc ttactcatgc aatttgcgac gcaggctgcc aaatatttcc
    67801 caaatgtgga gattattgag ctccatcatg acaagaaaaa ggatgctccg agtggaacag
    67861 ccattaaaac agctgagttg atggcagagg ttcgagagtc cattcagcaa ggtgcagcag
    67921 atgaggaaga gctgattgct ggtgctcgtg gtgctgactt tgatggtatg cgcatccact
    67981 cagttcgttt gccaggcttg gtagctcatc aggaagtcat ctttggcaat cagggagaag
    68041 ggttgaccct ccgtcatgac tcctatgatc gcatctcctt catgacagga gtcaatttgg
    68101 gaattaaaga agttgtcaag cgtcatgagc ttgtctatgg attagaacac ttattatgag
    68161 attaatgcaa atgccttctg aatttcagaa ggctttacca gtattagaaa aaattaaaga
    68221 agcaggcttt gaggcttatt ttgttggggg ctctgttcga gatgcccttc tccatagccc
    68281 tatccacgat gtggatattg cgacgtcttc ttatccagaa gagaccaagc agatttttcc
    68341 gcgaacagcc gatatcggaa tcgagcatgg aaccgtcttg gtcttagatg gggatgagga
    68401 gtatgaggta acaacctttc ggacagagga tgtctatgtg gactatcgca gacccagtgc
    68461 ggtttccttt gtgcgctcgc tagaagaaga cctcaaacgc cgtgatttca cagtcaacgc
    68521 ctttgccttg gatgagacag gagaaatcgt tgacttgttc catggtttag aagatttgga
    68581 aaagcaagtc ttgcgagcag ttggagtggc tagtgagcgt ttcaacgaag atgctttacg
    68641 gattatgcgt ggtttccgtt ttcaggctag tcttggtttt gcacttgagc cagaaacatt
    68701 taaagctatg aagaccttga cgccgctttt ggagaaaatt tctgtagagc gtaccttcgt
    68761 cgagtttgat aaactcttgc tggctccatt ttggagaagg ggcttggctt ccatgattga
    68821 gagtcaagct tatgactatc tccctgatat ggcatctagc caggacaagc tcaacagact
    68881 gtttgatttg gagactgatt ttacttttga atcctctgaa caagcctggg cggctttact
    68941 atgggctttg gagattgaaa atgcgcagtc atttttgaaa tcttggaaga cctcacgcca
    69001 gtttgccaag caagttcagg atttgctgat tattttggct ctgcgtgaaa atggagaatt
    69061 gagtaagcgt gattgttatc gctttgactt ggatttactt ttacaggctg aaaatcttcg
    69121 tcaagctcag ggaaaagaag tcaacccaca agtcattaaa gaaacctacc agagcttgac
    69181 tattcatgat aagaaagaaa tccaaatcaa cggcggtatt ttgatcaagg aatatggcta
    69241 tcagccaggc ccagacttgg gagagatttt aacagagatt gagtttgcca ttgtcgatgg
    69301 agaattggag aataatcgtg aagccatcca tgcttacctg agggagaaaa aatgagtgat
    69361 tttatcgttg aaaaactaag taaatccgtt ggtgacaaga ccgtttttag ggatatttcc
    69421 tttattatcc atgacttaga cagaattggt ttaatcggtg tcaatgggac tggcaagacc
    69481 acccttttgg acgtcctttc tggtgtttct ggatttgatg gggatgtcag tcctttttca
    69541 gctaaaaatg attaccagat tggttacttg actcaggatc ctgattttga tgatagaaag
    69601 acagttttgg atacggttct atctagtgaa ctcaaggaaa tccagctcat tcgtgagtat
    69661 gaattgatta tgctcgacta tagtgaggac aagcaggcgc gtttggaacg tgtcatggca
    69721 gagatggact ctctccaagc ttgggaaatt gagagtcagg tcaagaccgt tcttagcaaa
    69781 ttgggcattc aagacttatc tactcctgtt ggggaattgt caggtggtct gagaagacgg
    69841 gtacagttgg cacaagtctt acttggcaac cacgaccttt tgcttttgga tgagccgacc
    69901 aaccatctgg atattgcgat tattgagtgg ctgaccctct ttttgaaaaa ttctaagaag
    69961 accgtccttt ttatcactca cgatcgttat ttcttagacg ctttgtcaac acggattttc
    70021 gagttggagc gagcaggctt gacagaatat cagggcaatt accaggacta tgttcgcctt
    70081 aaggcagaac aggacgagcg cgatgcagct ctacttcata aaaaagaaca actctacaaa
    70141 caagaactgg cctggatgcg cagacaaccg caggcacgtg cgaccaagca acaagctcgt
    70201 atcaatcgtt tccatgatct gaaaaaggaa gtttcaggca gtagtgctga gacagacttg
    70261 actatgaact ttgaaaccag tcggattggg aagaaagtca tcgagtttca ggatgtttcc
    70321 tttgcctatg aaaataagcc cattttgcaa aattttaatc tcttagttca ggctcaagac
    70381 cgtattggaa ttgttgggga caatggtgtt ggaaaatcaa ccctacttaa cctgattgca
    70441 ggaagtcttg agccgacagc aggacaagtt gtgattgggg aaactgttcg catcgcctat
    70501 ttctctcaac aaattgaggg tttggatgaa agcaagcgtg tgatcaatta cctgcaggaa
    70561 gtggcagagg aggtcaagac cagtggtggt tctacgactt ccatcgctga gttgctggag
    70621 caattcctct tcccacgttc gacgcatggg actttgattg agaaattgtc agggggtgag
    70681 aaaaaacgtc tttatctcct caaactgctt ttggaaaaac caaatgttct tcttttagac
    70741 gagccaacca atgacctaga tattgcaact ttgacagtct tagagaattt cttgcaaggt
    70801 tttgcaggtc ccgttttaac agtcagtcac gaccgctatt tcttggataa ggtagcgacc
    70861 aagattctcg cttttgagga tggcaagatt cgtcctttct ttggtcatta caccgactat
    70921 cttgatgaaa aagcttttga aacagatatg gccaatcaag tgcaaaaggc cgaaaaggaa
    70981 aaagtggtca aggttcgaga agacaagaaa cgcatgacct accaagaaaa gcaggagtgg
    71041 gcaagtattg aaggtgatat tgaaaccttg gaaaaacgta tcgctgctat tgaagaggaa
    71101 atgcaggcta acggctctga ctttggtaag ctggctactc tccaaaaaga attggatgag
    71161 aaaaatgaag cactccttga aaaatacgaa cgctatgagt atctcagtga atttgatagt
    71221 taagactatt cgaaaatcaa agtgcaaact atgtcggctt cacattgccg actcaagtac
    71281 agcctgtgac tggcttccta atttgcactt tgatttttat tgagtataaa agaatagaaa
    71341 aatcccgtct catgaaagga tttctctatt cttttttggt ttcttgatga aagatatttt
    71401 gccaggtttc gtggcgacgc cagatactgg tatggatgat accatctaac tcatagcaga
    71461 tgagtttggt tttttgactg atggaagtaa tttgaatgtc cttgatagca gaatttaact
    71521 cttttttggt cttataagcc tctttatcca tctgctctcc atcttggcga atatagacaa
    71581 aatcatcagt caagagttct tctagttggt ttccttggtc aatcaattgt tcacgcataa
    71641 gcaatttttt atagacattg tctaaaattt catcctcagg gataggtgct ggttcgatat
    71701 ggacatcggt atcaaagacg ccaaaacgct cctccagcat agactcgacc tgatccgcga
    71761 tttcatggct ttcaaaaaca gacaagtcag gattcatctc tagtgtaata tccaggtaga
    71821 tgttgctacc gtaggtgcga cctctttgcg atttgacctt gctgattttg ggaatttcca
    71881 tgatagcctt ttggtagtcc tcgagcaggc ggtcgtcaaa gccatctgaa agactaaagg
    71941 aagactcgat gaagatatca taggcagtct tcaagataaa gaaagtgatg atgatagcaa
    72001 ccagtttatc cacaatcgga taattaaaac tactagctag gatggcaatg gcggttccaa
    72061 gtgaggtaac agcgtcagaa agattgtcct tagcagctgc cttcagcgcc ttggagttgg
    72121 atttcttact gaggcgagta ttgtagagat agaccacaaa cataatcgct gcagaaatga
    72181 ttcctagagt tgcaccaaga ggatcaatga ccgtttcttc ccgactgaga atcttttgaa
    72241 tggtatctct tagaacatcg aaaccgacat agaacatgat gatagaagtg atcaagcttg
    72301 ccaaatcttc aatcttccaa tgaccaaaac ggtggtcacg gtctgcaggc tggcgcgcca
    72361 tccgaatccc gattaagagg gctacatttc caatgatgtc cgatacgtta ttaaaaccat
    72421 cggccaccaa actggatgaa tgaaggagat gaccagctgc taatttggct gcagacaaga
    72481 tcaaataggt cgaaatactg ataatggctc cacgctcagc taacttgaga tttgagatag
    72541 attgcttcat tcaacttcct ttctagtcac atagcattct accattatac tggttttcaa
    72601 ggaaaaattc aaataaggca gtttttactc tttgaaaact ccccaaaatt tggtataatg
    72661 gtactactca agggagtagc tggcagaaac ctgtgatagt gtcgtcattc cgaattttat
    72721 gctgaaaagt atgctttccg gccctatctt aaacagcgag acttgttatg attaacaggt
    72781 ctctttttgt ttgtcgtgaa aagatatgac agaaagagag tctgttttgc acacaatgtc
    72841 aaggaggaga cacatgtcaa aagaacaaaa acgccaagcg ttttatactc agagccctga
    72901 agaggtcttg caggctgtgg atgcgaccga gcaaggtttg tcatcaagtg aggcggaaaa
    72961 gcgccttgcc gaatttgggc acaatgaact cgaagaaggc gagaaacgat caatcttggt
    73021 caaattcatc gagcaattta aggatttgat gattatcatc ctagttgcgg cagcaatctt
    73081 gtcagtcgtg acttctggtg gggaagatat cgcagatgcc attatcatcc tagctgtggt
    73141 tatcatcaac gctgcctttg gtgtttacca agaaggaaaa gctgaagaag ctattgaagc
    73201 cctcaaatcc atgtctagtc cagttgcccg cgttcttcgt gatggacaca tggcagagat
    73261 tgactctaaa gaattggtac caggcgatat cgttgccctt gaagcaggtg acgtggtacc
    73321 agcggaccta cgtttgatag aagccaactc tcttaaaatt gaagaagcag ccttgacagg
    73381 tgaatctgta ccagtcgaaa aagacttgtc agtcgagctt gcgacagatg ctggtattgg
    73441 tgaccgtgtc aacatggcct tccaaaactc aaacgtaacc tatggtcgtg ggatgggtgt
    73501 tgttgtcaat acaggtatgt acactgaagt tggtcatatt gctggtatgc ttcaagatgc
    73561 ggatgagact gatacaccac tcaaacaaaa tttgaacaac ctttctaagg tattgaccta
    73621 tgctatcttg gtcattgccc ttgttacttt tgtagtgggt gtcttcattc aagggaaaaa
    73681 tccacttggt gagttgttga cttctgttgc ccttgccgtt gcagccattc cagaaggact
    73741 tcctgctatc gttaccatcg ttctttctct tggtactcaa gttttggcca aacgacattc
    73801 catcgttcgt aagttgccag cagttgaaac acttggttca actgaaatca tcgcttctga
    73861 taagactggt acgctgacta tgaacaagat gacagtcgaa aaagtcttct acgatgcggt
    73921 tctacatgac tcagctgatg atattgaact aggtcttgaa atgccactac ttcgttcagt
    73981 tgtcttggcc aatgatacga aaatcgatgt ggaaggtaac ttgattggtg acccaaccga
    74041 aacagccttt atccaatatg ccttggacaa gggctatgat gtcaaaggtt tcttagagaa
    74101 atatcctcgt gtagctgaat tgccatttga ctctgaccgt aagctcatgt caacagttca
    74161 cccattgcca gatggtcgtt tccttgtagc agtcaagggt gcgccagacc aactcttaaa
    74221 acgttgtctt cttcgtgata aggctgggga tattgctccg attgatgaga aggttacaaa
    74281 tctcattcat acaaacaatt ctgaaatggc tcatcaagcc ttgcgtgtcc ttgcaggtgc
    74341 ttataagatt atcgatagta ttccagaaaa tctcacttct gaagagcttg aaaatgattt
    74401 aatttttact ggtttgattg ggatgattga ccctgaacgt cctgaagccg ctgaggctgt
    74461 tcgtgtggct aaggaagcgg gaatccgtcc aattatgatt acaggtgacc accaagacac
    74521 agcggaagcc attgccaaac gtttgggaat cattgacgca aacgatacag aaggtcacgt
    74581 tttaactggt gctgaactca atgaactgtc agatgaagaa tttgaaaaag tcgttggtca
    74641 atactctgtt tatgcccgtg tgtctccaga acacaaggtt cgtatcgtca aggcttggca
    74701 aaaacaaggt aaagtcgttg ccatgacagg tgatggtgtc aatgacgcgc cagctctgaa
    74761 aacagccgat atcggtatcg gtatgggaat cactggtaca gaagtttcta agggggcttc
    74821 tgacatgatt cttgcagatg ataactttgc gactattatc gtcgcagtgg aagaaggacg
    74881 taaggtcttc tcaaacattc aaaagactat tcagtaccta ctttctgcta atactgctga
    74941 agtattaacc atcttcctat caaccttgtt tggttgggat gtcttgcagc cggttcatct
    75001 tttgtggatc aacttggtaa cggatacctt cccagctatt gctcttggtg ttgaacctgc
    75061 ggagcctggt gtcatgaatc ataaaccacg tggacgcaag gcaagcttct tctcaggtgg
    75121 tgttttgagt tctatcattt atcaaggtgt actccaagca gctcttgtta tgagtgttta
    75181 tggccttgcg attgcttacc cagttcatgt gggtgacaat catgctattc atgcagatgc
    75241 cctaacgatg gcctttgcaa cccttggttt gattcagctc ttccatgcct acaatgtcaa
    75301 gtctgtctac caatccatct tgacagttgg cccattcaag tctaagacct ttaactggtc
    75361 catcttggta tcctttatcc ttctcatggc aacaatcgtt gtagaaccgc ttgaaggaat
    75421 cttccacgta accaaactag acttgtcaca atggggaatt gttatggctg gaagcttttc
    75481 aatgattatc atcgtcgaaa tcgttaagtt tattcaacgc aaactcggtt ttgacaaaaa
    75541 tgcgatttaa gggaggtttc ggatgtcagc atatcaatta ccgaccgtat ggcaggatga
    75601 agctagtaat caaggagctt ttacggggct aaacagacca acagcaggtg cccgtttcga
    75661 acaaaacttg ccaaaaggag aacaagcttt tcagctttat tcactgagaa caccaaatgg
    75721 tgtgaaggtt actatcttat tggaagaatt actagaagct ggttttaagg aagcggctta
    75781 cgacttgtat aagattgcta tcatggatgg ggatcaattc ggatcagact ttgtgaagct
    75841 caatccaaat tccaagattc cagccttatt ggaccagtca ggtactgaag atgtaagagt
    75901 ctttgagtct gctcatattc ttctttacct tgctgagaaa tttggagcct ttttaccaag
    75961 taatcctgtg gaaaaggtag aagttttgaa ttggctattc tggcaagcag gtgcagcacc
    76021 ttttctaggt gggggatttg gacatttctt caattatgct cctgaaaaat tggaatatcc
    76081 tattaaccgt tttacgatgg aagtgaaacg ccagttggat ttattggata aggaattggc
    76141 tcagaaacct tatattgcag gcaatgacta tacgattgca gatattgcta tctggtcttg
    76201 gtatggacag ttagttcaag gaaatcttta ccaaggttct gcaaaattct tggatgcctc
    76261 aagttatcaa aatctagtaa aatgggcaga aaaaattgcc aatcgtccag ctgttaagcg
    76321 tggcttggaa gtaacttata cagaaattaa atagcaaaaa agtcatcttc ggatggcttt
    76381 ttgctacagt tgagggaaag ggtttgcagt tatcggcttt tgtgctataa ttgctataat
    76441 atagtaaaaa gcaagaggag tgtgaggaag tggaaaagaa aattgtgaag gatatcttat
    76501 ttttatctca agtgtctcag ccggcaagtc aggaggacct ttatcttgcc agagatttgc
    76561 aggatacact cttagcaaat cgtgatacct gtgttggtct agctgccaat atgattgggg
    76621 tgcagaagcg cgtgattatc tttaatcttg gcttggttcc cgtggtcatg tttaacccag
    76681 tgcttctgtc ctttgaagga tcttatgagg cagaagaagg ctgtttgtcc ttggtaggtg
    76741 tgagatcaac taagcgttat gaaaccataa ggcttgccta tcgtgacagc aagtggcagg
    76801 aacagaccat taccttgaca ggcttcccag ctcagatttg ccagcatgag ctggatcact
    76861 tggaaggacg aattatttag gaggaaagca aatgaaacga atagtctttg aacttatttt
    76921 tatcgcaacg acctggtata tctttttacc gccccttaac ctgaccagct gggaatttct
    76981 cttcttcctc tgtgggcatt tgttagttgt ggcaatctta tttggctttg gcaaggggat
    77041 aaaccttgtc aaaacggttc atgtgcgcca cggtaaggcg gaagctgcct taaatcttga
    77101 gggtttcaaa atcaatcggt tagggaaaat tctgttagct tcgattggag gaattcttct
    77161 cttggcagct ttggtttcct tggtaacttc tagcatgttt caggctaaaa attatgccaa
    77221 tgtagtcacg gttacggaaa aagactttac tgaatttcct aagagtgaca ccagtaaggt
    77281 tcctatccta gatagaagta ctgctgaaaa aattggagac cgctacttgg gttccctaac
    77341 cgataaggtg tcgcaatacg tagcggcaga tacctatacc caattgacaa ttgatgggaa
    77401 accttatcgg gtcacaccac tagaatatgc agaccctatc aaatggttta acaatcaagc
    77461 caagggaatt ggtgagtata tcaaggtgga catggtaact ggaaatgcgg atttggtgga
    77521 cttgaagaca ccaatcaagt attcagactc ggagtatttt aaccgtgatg tcaaacgtca
    77581 cctgcgcttg aagtacccga ccaaaatctt taaaactcca tcttttgagg tggacgatga
    77641 gggcaatcct ttctatgtag caacggttta ccaaaagcaa tttggacttg ctgttcctcg
    77701 tcctgcttca gtcattatct tggatgctac aaatggagaa accaaggaat acagcttatc
    77761 agatgttcca gaatgggtgg acaggatcta tccagcagag gaaaccattg agcaaattaa
    77821 ctacaacggc aagtacaagg acggtttctt gaatgccatg atttccaaga aaaacgtgac
    77881 ccagactacc aagggctata attacttgtc tatcggtaat gacatctatc tctacacagg
    77941 tgtgacgtcg gctaatgcgg atgagagtaa tcttggtttc atccttgaaa atatgcgaac
    78001 aggagaaatc actaagtata gcttggcttc tgcgacagaa gaatcagccc gtgaatcagc
    78061 agaaggtgct gttcaggaga aatcctacaa agcaaccttc ccaatcctca tcaacctcaa
    78121 tgacaagcct ctctacatca tgggcttaaa ggacaatgct ggcttggtca aagagtacgc
    78181 cctggtagac gcagtcgagt accaaaatgt tatcgttgct actacagtgg aagagatgct
    78241 cagcaagtat gccaataaaa acgaccttga aattgacaat gcaacgacag aaagcatcaa
    78301 gggagtagta gcagacctca aatcagctgt tatcaagggc gacaccgtct acttctttaa
    78361 agttgatggc aagatttaca aggttaaggc ctcagtatcc gatgaccttc cttaccttga
    78421 aaatggtaga accttcgaag gtcaagtagg aaaagacagc tatctcaaga cctttaaagt
    78481 acagtaatac tctgcgaaaa tctcttcaaa ccacgtcaac tttatctgca acctcaaagc
    78541 tgtgctttga gcaacctgcg gctagtttcc tagtttgctc tttgattttc attgagtata
    78601 aaaaaggttt atttaagaaa tatatgttat agtaaaataa attaagacta atggaggaca
    78661 aagaaatggg tttttatttg atggttgctt caatgctact cggactgctc gctttgaaga
    78721 taggtttttc tcagttcaag gagaacaaag ataaattctt atctatctta acaagtttag
    78781 ctgggctagc ccttgttctc gtggctgtct ggttaggatg gcccaaataa atagaaaaac
    78841 ctcggtcaaa ccgaggtttt tcagatgaat ttcttggttg tggctaaaaa atatgctaca
    78901 ctatcaatat gaagatttta atccctacag caaaagaaat gaatacagac ttgccgagta
    78961 tcgagacaac tcttttaaga tcagaaagtc aggctgtact tgatgccttg gctctctatt
    79021 ctgccagtca attggaaagt ttctacaagg tatcagctga gaaggctgcg gaagaatgtc
    79081 aaaatatcca agctttgaaa aggcaaactg ctcaacacta cccagccttg aagctttttg
    79141 atgggcttat gtaccgtcat atcaagagag acaaactgac cgaggtagaa caagcctatc
    79201 ttgaaaatca tgtcttcatt acctcggctt tgtacggagt cgttccagcc ttgtcgccta
    79261 tggcacctca ccgtttggat tttttgatga aattaaaagt cgctggtaag actttgaaga
    79321 gccattggaa ggcagcctat gatgaagctg tgaagcagga agaagtgatt ttctctctct
    79381 tgtcatcaga gtttgagact gtattttcta aggaaatcag agcaaagatg gtgaccttca
    79441 aattcatgga ggatagaggc ggtcagctga agattcactc aactatctcc aagaaagcgc
    79501 gcggggcctt tctaacagct ttaatagaaa atcaagtaca aactgtgggg gaagcacgtc
    79561 gcttgaactt tgctggattt gtttaccgag aagatttgtc acaaccacag ggattggttt
    79621 ttgtaaagga agtatagaaa tcagataaga gaaaagtcag cacgattatg ctgacttttt
    79681 tgataactta taaagtattg gacaaatgaa tctcatttga taaggtgtta agatgattaa
    79741 ccaaattcat gattgacaga tgatttcggc aaataaactt cttggtaatc cctgaaatat
    79801 agaaattaga cacgatgata tcgtaatctg tctgatttaa aatctcagga cttgttttta
    79861 attcatccca aatatcgaag gtaaagcggt tattacagta ataggaaagc atatcaacaa
    79921 aggtaaggga tatagcatgg tcaaagttac tgataatcaa aaccttgata ggtggtcgat
    79981 tttctaacaa ctgagtagag aggttttcag catgggttaa gatggtgtac atcaagtgtt
    80041 ccaactgttc aggatggtca tgctgtccaa ttgcctgacg gtattgagcc agttcttgac
    80101 gcgcacttcc cataaagtct gggaagtaaa cttcaaattt tttaatcgtc aatgcttttt
    80161 gttcaaataa gattggggta gaaaagattt cctgtctttc aaagaaagca gtgttgtgta
    80221 aatgccaaat cagctcatcg tggttagtaa aagtaatctt atattgtttt gataggcgtt
    80281 ctaatatttg actaagtaat tggtaagagt atcttgcttg actgttatct tctaaagagt
    80341 tgaagaattc ttgaggatct aggaaaatat cattctgaag aaaagaaata aaaatttgag
    80401 cgattgtatc tggagtcatt tcaagcccaa aatgtttaga gaaataagca agtgtctcct
    80461 ggaaatttgg aatgctcttt aaaagaggat aatattcttt gtaaaagtgg ttggggaggt
    80521 caatgaagtg accattttta accctgtgga tactgatagc tatcatcagt ttgtacattc
    80581 tataaattga aaatcgcatt ggataattcg tgattttata gaagaagtca gcaaactctg
    80641 ttaaatcttc ctcaggaagg tcaggaaaag gccaatctag gaaataatag cgctcagaaa
    80701 agtattgggc aaaaaagtaa cgaatatcga tctcatttcc acgtatctcg gatggagtaa
    80761 aagataattc aatttgaaac tgagatgaaa gaacctttgt aatatttctg cccagtcgat
    80821 agaggttggc actactaaag taaagatttt ctattgttcg ataaataggt agcccctcat
    80881 tgaagaacat atactctagt aattgaaaag attgagaatt agcaagaaaa tattgataaa
    80941 tatcttctac actagtgtta acttctaaat ctatcatgat tccgttaaca gaagattgga
    81001 tgttaataga tggaaaggca atacgtaatt catttaaatc actttttaag attcgttctg
    81061 tacatcctaa tttttcggct agttcatgta atttcatcca attacgattc tgaattaggg
    81121 tttccattaa gcgtaattgt ctttgaactt ttgtggataa aaggtttctc atacgggtat
    81181 ttcctccata attcattata tctttttttg tctaagtagt ataaaaaaat tagagcaaga
    81241 aaattgtcgt tagtaatcgg aaaaattaga ataatataag tggcttttaa gtgcaaaaac
    81301 agaatatatt aattgttcag aaaatattga ttaatgcctc aaatagttgt acattgtaaa
    81361 ctataaaata ctatctagga gtttaaaatg aaacattcac ataaaaaatc atttgactgg
    81421 tatagcatgc aacaacgtta ttctattcgt aagtattact ttggtgcagt tagtgtcttg
    81481 ctcggtaccg ctttggtatt aggtgcagca gctagtgtcc aaacagtaca agcggaagaa
    81541 aacaaacaag aaactaccaa tagtatttct gttggtaggg gagaagcagc tactaaacca
    81601 gcagaggttt ctgcgtctaa taaagagaaa acctatgcag ctccaactgt agctaatcca
    81661 gtagaaacga ctccagttaa aactggagaa gttactaaac cagcagaaaa agttgaagaa
    81721 gcaaaagaca aaaaagagga agtaacgcat caagatgcta ttgacaagtc aaaattgtta
    81781 acggctcttt cgcgtgctaa aaagttagaa agcaagttat atacagaagc aagtgctgct
    81841 aacttgcaaa caagtatcca agctggtcaa agcttgcttg ggaaagcaga tgcatctgaa
    81901 gctgaattat cagcagcaga gtcatctatt caatcatcta ttattggtct agaacttcgt
    81961 tctaactcta acaaaggaac tgtatcagaa acgcctgtag caaagaaagc taatatagtt
    82021 gaagcgaagg aagagactaa accagctgta acaacgactg aacgttcagc tgttgatagc
    82081 gctattttgc caattagcac agctgctaaa gtagaaacaa cttcagctcc agcatctact
    82141 aatgaaatct tgaaaccaag tttgagcctt tctgatgctc gccaaaatcc agctatccgt
    82201 aaggaagatg ttgatagagg gtatagtggt tttagaacag caggaagtgg ctttagagcg
    82261 gctggaagtg gttttagagc agctggacca gaaaataaac caatcttaaa tccaaataat
    82321 actattgcat tttctgacat cagtcagggc ttacattcat ttcgtggtat aggacattca
    82381 cgtggtggtc gtgaaatcca ttatgatgta acgacagtac gtagaggtaa tagattgaat
    82441 ttcacaatta aatactctgg tccaggtgaa tttgttaata ataattttat cttggataaa
    82501 ggggatggat ttggaaatcc ttcaaatgca acgatcacaa gttcaaatcc aagagtaagg
    82561 gagcaatcaa aatctattag tcagggtgcc aactacgtat ctcactcagg atacagtatg
    82621 acctctgcta cttcaacaaa tacggaacaa actatcagat ttagtttgcc tatcattaat
    82681 ccaaatggtg atttgtctgt tcgtttgaaa ccagttactt ttaacgtgga ccaaggtggt
    82741 ggtggtgccg ctactagcaa tgacccatac agtaactcca actattatca tagagcaaat
    82801 ccactcctct tggatgcaaa cccttatggt ggtactaata ataagactgt ttcagaagac
    82861 attgacttcc aaactgtcta tcttccaact agtaagttac cagaaggtca aactagatta
    82921 gttcgagaag gtgaaaaagg acaacgtcaa attacctata aagtacatcg atttggtaac
    82981 gaaacacttt taggattgcc aattagtaat agagttacta aagaagctaa gccacgtatt
    83041 atgcaaattg gtgtggctaa agagttaatc gatacagtaa aaccacgtgt tgatcaaaat
    83101 aaagttggtg atacaaataa cctcactttc tatcttgata acgatggaaa cggtgtttat
    83161 actgagggcg tagacgaact tgttcaaaaa attgctatta aagatggagc caagggtgaa
    83221 aaaggagacc aaggtgaacg cggtctaact gg
//
LOCUS       DAVKBK010000002        83112 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVKBK010000002 DAVKBK010000000
VERSION     DAVKBK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.002"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(525..617)
                     /locus_tag="VWX69_000085"
     CDS             complement(525..617)
                     /locus_tag="VWX69_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU9191500.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            778..1749
                     /gene="ruvB"
                     /locus_tag="VWX69_000086"
     CDS             778..1749
                     /gene="ruvB"
                     /locus_tag="VWX69_000086"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU9191501.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1730..2302
                     /locus_tag="VWX69_000087"
     CDS             1730..2302
                     /locus_tag="VWX69_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU9191502.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            2533..3291
                     /locus_tag="VWX69_000088"
     CDS             2533..3291
                     /locus_tag="VWX69_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU9191503.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3300..4103
                     /locus_tag="VWX69_000089"
     CDS             3300..4103
                     /locus_tag="VWX69_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU9191504.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4125..5384
                     /gene="rseP"
                     /locus_tag="VWX69_000090"
     CDS             4125..5384
                     /gene="rseP"
                     /locus_tag="VWX69_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU9191505.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRHKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5397..7250
                     /locus_tag="VWX69_000091"
     CDS             5397..7250
                     /locus_tag="VWX69_000091"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU9191506.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7350..8729
                     /gene="bglA"
                     /locus_tag="VWX69_000092"
     CDS             7350..8729
                     /gene="bglA"
                     /locus_tag="VWX69_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9191507.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            8921..10729
                     /gene="glmS"
                     /locus_tag="VWX69_000093"
     CDS             8921..10729
                     /gene="glmS"
                     /locus_tag="VWX69_000093"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU9191508.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            10848..11897
                     /locus_tag="VWX69_000094"
     CDS             10848..11897
                     /locus_tag="VWX69_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU9191509.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(11997..15794)
                     /gene="spuA"
                     /locus_tag="VWX69_000095"
     CDS             complement(11997..15794)
                     /gene="spuA"
                     /locus_tag="VWX69_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU9191510.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDTHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVKIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQEASV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            16210..16623
                     /gene="rpsL"
                     /locus_tag="VWX69_000096"
     CDS             16210..16623
                     /gene="rpsL"
                     /locus_tag="VWX69_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU9191511.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16643..17113
                     /gene="rpsG"
                     /locus_tag="VWX69_000097"
     CDS             16643..17113
                     /gene="rpsG"
                     /locus_tag="VWX69_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU9191512.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17537..19618
                     /gene="fusA"
                     /locus_tag="VWX69_000098"
     CDS             17537..19618
                     /gene="fusA"
                     /locus_tag="VWX69_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU9191513.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19722..24113
                     /locus_tag="VWX69_000099"
     CDS             19722..24113
                     /locus_tag="VWX69_000099"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU9191514.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24215..24478
                     /locus_tag="VWX69_000100"
     CDS             24215..24478
                     /locus_tag="VWX69_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU9191515.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24471..24749
                     /locus_tag="VWX69_000101"
     CDS             24471..24749
                     /locus_tag="VWX69_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU9191516.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24770..24922
                     /locus_tag="VWX69_000102"
     CDS             24770..24922
                     /locus_tag="VWX69_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191517.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            24944..26185
                     /locus_tag="VWX69_000103"
     CDS             24944..26185
                     /locus_tag="VWX69_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU9191518.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            26195..26425
                     /locus_tag="VWX69_000104"
     CDS             26195..26425
                     /locus_tag="VWX69_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9191519.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            26783..27505
                     /locus_tag="VWX69_000105"
     CDS             26783..27505
                     /locus_tag="VWX69_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9191520.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            27722..29056
                     /gene="pepC"
                     /locus_tag="VWX69_000106"
     CDS             27722..29056
                     /gene="pepC"
                     /locus_tag="VWX69_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU9191521.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(29112..30023)
                     /locus_tag="VWX69_000107"
     CDS             complement(29112..30023)
                     /locus_tag="VWX69_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9191522.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(30047..30850)
                     /locus_tag="VWX69_000108"
     CDS             complement(30047..30850)
                     /locus_tag="VWX69_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU9191523.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(30878..31867)
                     /gene="manX"
                     /locus_tag="VWX69_000109"
     CDS             complement(30878..31867)
                     /gene="manX"
                     /locus_tag="VWX69_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU9191524.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(32100..33119)
                     /gene="adhP"
                     /locus_tag="VWX69_000110"
     CDS             complement(32100..33119)
                     /gene="adhP"
                     /locus_tag="VWX69_000110"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU9191525.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWAVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(33471..34283)
                     /locus_tag="VWX69_000111"
     CDS             complement(33471..34283)
                     /locus_tag="VWX69_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9191526.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            34473..35891
                     /locus_tag="VWX69_000112"
     CDS             34473..35891
                     /locus_tag="VWX69_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU9191527.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            35944..36651
                     /locus_tag="VWX69_000113"
     CDS             35944..36651
                     /locus_tag="VWX69_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9191528.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            36746..37720
                     /gene="folP"
                     /locus_tag="VWX69_000114"
     CDS             36746..37720
                     /gene="folP"
                     /locus_tag="VWX69_000114"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU9191529.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALATGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            37722..39044
                     /locus_tag="VWX69_000115"
     CDS             37722..39044
                     /locus_tag="VWX69_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9191530.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            39025..39579
                     /gene="folE"
                     /locus_tag="VWX69_000116"
     CDS             39025..39579
                     /gene="folE"
                     /locus_tag="VWX69_000116"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU9191531.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            39622..40434
                     /gene="folK"
                     /locus_tag="VWX69_000117"
     CDS             39622..40434
                     /gene="folK"
                     /locus_tag="VWX69_000117"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU9191532.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(40479..40796)
                     /locus_tag="VWX69_000118"
     CDS             complement(40479..40796)
                     /locus_tag="VWX69_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU9191533.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            41153..41599
                     /gene="rplM"
                     /locus_tag="VWX69_000119"
     CDS             41153..41599
                     /gene="rplM"
                     /locus_tag="VWX69_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU9191534.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLEQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            41618..42010
                     /gene="rpsI"
                     /locus_tag="VWX69_000120"
     CDS             41618..42010
                     /gene="rpsI"
                     /locus_tag="VWX69_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU9191535.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(42272..42694)
                     /locus_tag="VWX69_000121"
     CDS             complement(42272..42694)
                     /locus_tag="VWX69_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9191536.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            42841..43017
                     /locus_tag="VWX69_000122"
     CDS             42841..43017
                     /locus_tag="VWX69_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191537.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            43419..45632
                     /locus_tag="VWX69_000123"
     CDS             43419..45632
                     /locus_tag="VWX69_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU9191538.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(45854..46330)
                     /locus_tag="VWX69_000124"
     CDS             complement(45854..46330)
                     /locus_tag="VWX69_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU9191539.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQAQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFSKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            46553..49756
                     /locus_tag="VWX69_000125"
     CDS             46553..49756
                     /locus_tag="VWX69_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU9191540.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKGG
                     AITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYYWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            50136..50521
                     /gene="tnpA"
                     /locus_tag="VWX69_000126"
                     /pseudo
     CDS             50136..50521
                     /gene="tnpA"
                     /locus_tag="VWX69_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(50900..51529)
                     /locus_tag="VWX69_000127"
     CDS             complement(50900..51529)
                     /locus_tag="VWX69_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU9191541.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(51539..52540)
                     /locus_tag="VWX69_000128"
     CDS             complement(51539..52540)
                     /locus_tag="VWX69_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU9191542.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(52571..53212)
                     /locus_tag="VWX69_000129"
     CDS             complement(52571..53212)
                     /locus_tag="VWX69_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU9191543.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(53231..54046)
                     /locus_tag="VWX69_000130"
     CDS             complement(53231..54046)
                     /locus_tag="VWX69_000130"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU9191544.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            54317..54751
                     /locus_tag="VWX69_000131"
     CDS             54317..54751
                     /locus_tag="VWX69_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9191545.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQESVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            54763..55953
                     /locus_tag="VWX69_000132"
     CDS             54763..55953
                     /locus_tag="VWX69_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEU9191546.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            55964..56455
                     /locus_tag="VWX69_000133"
     CDS             55964..56455
                     /locus_tag="VWX69_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9191547.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            56470..57249
                     /locus_tag="VWX69_000134"
     CDS             56470..57249
                     /locus_tag="VWX69_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9191548.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            57236..58054
                     /locus_tag="VWX69_000135"
     CDS             57236..58054
                     /locus_tag="VWX69_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9191549.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGENQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            58054..58347
                     /locus_tag="VWX69_000136"
     CDS             58054..58347
                     /locus_tag="VWX69_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9191550.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            58369..60270
                     /locus_tag="VWX69_000137"
     CDS             58369..60270
                     /locus_tag="VWX69_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU9191551.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFMSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            60330..61331
                     /locus_tag="VWX69_000138"
     CDS             60330..61331
                     /locus_tag="VWX69_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9191552.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(61441..61776)
                     /locus_tag="VWX69_000139"
     CDS             complement(61441..61776)
                     /locus_tag="VWX69_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191553.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(61787..62029)
                     /locus_tag="VWX69_000140"
     CDS             complement(61787..62029)
                     /locus_tag="VWX69_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191554.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(62045..62239)
                     /locus_tag="VWX69_000141"
     CDS             complement(62045..62239)
                     /locus_tag="VWX69_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191555.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            62405..63355
                     /gene="rsmH"
                     /locus_tag="VWX69_000142"
     CDS             62405..63355
                     /gene="rsmH"
                     /locus_tag="VWX69_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU9191556.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPEGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            63367..63684
                     /gene="ftsL"
                     /locus_tag="VWX69_000143"
     CDS             63367..63684
                     /gene="ftsL"
                     /locus_tag="VWX69_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU9191557.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            63688..65940
                     /locus_tag="VWX69_000144"
     CDS             63688..65940
                     /locus_tag="VWX69_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEU9191558.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNDGLTTGGMMTFLQGF
                     AHSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYSGQLPADNIVNIAMSAF
                     GQGISVTQTQMLRAFTAIANDGVMLEPKFITALYDPNDQTVRKSQKEIVGNPVSKDAA
                     SQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAQIADEKNGGYLTGST
                     NYIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPA
                     KNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAP
                     NQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGSVVQKQDVRTNTAIKN
                     IKKIKLTLGD"
     gene            65942..66922
                     /locus_tag="VWX69_000145"
     CDS             65942..66922
                     /locus_tag="VWX69_000145"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU9191559.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIASVLVAFFFALFSNQLSNNVGMILFILVLYGLIGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNYKP
                     AKVFMGDVGSLSLGGMLAAISMALHQEWTLLIIGIIYVFETTSVMMQVGYFKMTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVELLASLLTLAILYLR"
     gene            67257..69362
                     /locus_tag="VWX69_000146"
     CDS             67257..69362
                     /locus_tag="VWX69_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9191560.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAEVDGQMQQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     EAEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAIEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGPTGVGKTELAKQLALDMFGTKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLF
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(69658..70140)
                     /locus_tag="VWX69_000147"
     CDS             complement(69658..70140)
                     /locus_tag="VWX69_000147"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU9191561.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(70235..71719)
                     /locus_tag="VWX69_000148"
     CDS             complement(70235..71719)
                     /locus_tag="VWX69_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU9191562.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDATRAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            71872..73482
                     /locus_tag="VWX69_000149"
     CDS             71872..73482
                     /locus_tag="VWX69_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU9191563.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVEMTD"
     gene            complement(73613..75043)
                     /locus_tag="VWX69_000150"
                     /pseudo
     CDS             complement(73613..75043)
                     /locus_tag="VWX69_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398391.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            75200..76645
                     /gene="cps4A"
                     /locus_tag="VWX69_000151"
     CDS             75200..76645
                     /gene="cps4A"
                     /locus_tag="VWX69_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU9191564.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQ
                     EFSALHRKFLFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGTDRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            76647..77378
                     /locus_tag="VWX69_000152"
     CDS             76647..77378
                     /locus_tag="VWX69_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEU9191565.1"
                     /translation="MIDIHSHIVFDVDDGPKSIEESKALLREAYNQGVRMIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHAGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     gene            77387..78079
                     /gene="cpsC"
                     /locus_tag="VWX69_000153"
     CDS             77387..78079
                     /gene="cpsC"
                     /locus_tag="VWX69_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU9191566.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            78089..78772
                     /gene="cpsD"
                     /locus_tag="VWX69_000154"
     CDS             78089..78772
                     /gene="cpsD"
                     /locus_tag="VWX69_000154"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HEU9191567.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARTGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTAIGEVNKRDVQKAKQQLEQTEKLFLGVVLNKLDISVDKYGVY
                     GSYGNYGKK"
     gene            78788..80155
                     /locus_tag="VWX69_000155"
     CDS             78788..80155
                     /locus_tag="VWX69_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU9191568.1"
                     /translation="MDEKGLKIFLAVIQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            80161..80904
                     /locus_tag="VWX69_000156"
     CDS             80161..80904
                     /locus_tag="VWX69_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEU9191569.1"
                     /translation="MNERMQILGVTIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCHEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEILQDMLKVFKQRYPNLNVVGYRNGYFSPEDEKKIQEDIKGGKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQKLNLEWLFRVVN
                     EPKRLFKRYFIGNVTFIKRVLDEKRKSKK"
     gene            80879..81964
                     /locus_tag="VWX69_000157"
     CDS             80879..81964
                     /locus_tag="VWX69_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU9191570.1"
                     /translation="MKSENQKNNILHISRTMDIGGAERIVYQLSSDLKDEFDSVHVAS
                     TGGLWESKLLSKGVQHHKILDVDSKNPLTMVKILSSFYRIIKNNDITIVHTHHRMAAF
                     YIRLLKIINPKLIHVYTAHNVFKNKLPLYKFSLKKAYCVAVSKAVNDNLKHDVGISDS
                     TVIYNGVVFEKTDKLVGEIVNYNGIKLGCIARLSEQKGLTYLIDAMSLVKHRNITLFI
                     VGDGELRDELENKVKQLNLQKSVIFLGYRKDIVECINSFDYLVSSSLYEGFGLNAIEA
                     FMKGKTMVSSDIPGINEVVNNKNGILVPVKDDVALARAIEKLATDKKLREKLAYQAKK
                     DYETKFNYSLFLDNYRRLYRKLMGESK"
     gene            81961..83049
                     /gene="wecB"
                     /locus_tag="VWX69_000158"
     CDS             81961..83049
                     /gene="wecB"
                     /locus_tag="VWX69_000158"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000758382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEU9191571.1"
                     /translation="MKKVMLVFGTRPEAIKMCPLVNELKQNDSIKTLVCVTGQHKEML
                     EQVLEVFKVVPDYDLGIMKANQTLFTITTSILDKIQAVLEKEKPDLVLVHGDTTTTFA
                     TALAAFYMGIKVGHVEAGLRTYNLQSPFPEEFNRQTTSIIADYHFAPTEVAKENLLRE
                     DRKNIFVTGNTVIDALKTTVQDNYHHPILEWAKGSKLIMLTAHRRENLGKPMENMFNA
                     VNRILNEFEDVKVVYPIHKNPKVRELASKVFGDNERMKIIEPLEVIDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVVAGTLKLVGTEEENIYSNFKLLLEDET
                     EYNKMSKASNPYGDGMTCKRIVDIILEV"
BASE COUNT        24702 a        15067 c        18769 g        24574 t
ORIGIN      
        1 tttttcataa taatctccct taacttcacc caatcaggtg gagtttttta gctctatttc
       61 aggcttttgg ggactattct aaaaataatt tttcgatatt tttcggtatt tttcggattt
      121 tggtcgggga attggcgggg acttttttag cgaatataac taagaaatag gtctgtggtc
      181 gcttcagcta gttcaaactc aatttgattg taagtgactg ttaattgaag aactggaact
      241 actgtaataa tgattttgct tgtctagtag tggcgtatta aatgagaagt aacatgtaag
      301 attgtctctt cgtttacgaa atcaaaattt ctatgaaatt gatagaatcc ctaacgttct
      361 cttaatctta accgtcttgt cgtacagcgg ttgaagaaaa tgtaaacctt tgacaaaatt
      421 cgtgaactat gggataataa aaaggaattg agtactagtt ctatatcata ggctagaaaa
      481 gaccccaagc tcacgaccaa ataagcttga ggtctttttt gacactattt gtccttgttt
      541 agccatttat cgactatacg aagaacgaca ccgaccacaa ttggtccgat gatagttttg
      601 agtactaatt ccatcatggg ctatctcacc tcctttcgta ggcggtgtag cagtgtcgta
      661 gaatattata ccacataagt gctaaactta ggagtcaccc aatcaggtgg cttttttgtt
      721 tgtggcttgg ttttttgata taatagagcc atgagtagaa ttttagataa tgagataatg
      781 ggggatgagg agttagtaga acgcacgctc cgtcctcagt atttacgtga atatatcgga
      841 caggataagg tcaaggacca gctacaaatc tttattgaag ctgccaaaat gcgggatgaa
      901 gcgctggatc atgtgctctt atttgggcct ccaggtctcg ggaaaacgac catggccttt
      961 gttattgcca acgaactggg agtcaatctt aagcagacgt cgggtccagt cattgaaaaa
     1021 gccggagatc tggtagctat tttgaatgag ttagagcctg gggatgtact ttttattgat
     1081 gagatccatc gtttgccaat gtcagtggaa gaggtgcttt atagtgctat ggaggacttc
     1141 tacatcgata ttatgattgg ggctggtgag ggtagtcgta gtgttcattt ggagttacca
     1201 ccttttacct tgattggtgc gacgactcgg gctggtatgc tctccaatcc gctacgggca
     1261 cgttttggga ttacaggcca tatggagtat tatgcccatg ctggcttgac agaaattgtc
     1321 gagcggacgg cagatatttt tgagatggaa atcactcatg aggcagcatc tgagttggcc
     1381 ctacgtagtc gtgggacccc tcgtattgcc aatcgtctcc tcaagcgcgt gcgcgatttt
     1441 gcccagataa tggggaatgg ggtaattgat gatattatta ccgataaggc tttgactatg
     1501 ctggatgttg accatgaagg tttggactat gtggatcaaa aaatccttcg taccatgatt
     1561 gagatgtaca gtggaggacc tgttggtcta ggaactcttt ctgtgaatat cgccgaagag
     1621 cgtgagacag ttgaagatat gtatgagcct tacttgattc aaaaaggttt tatcatgcgg
     1681 acacggtctg gacgggtggc gactgctaag gcatatgagc acttaggtta tgaatacagt
     1741 gaaaaataag caagaaatct tagaggcttt tagagaaaat ccagatatga tggccattct
     1801 gacgatcatc cgagaccttg gtctgaaaga ctcgtggttg gcagcaggtt ctgtcagaaa
     1861 tttcatttgg aatcttttgt cagacaaatc cccttttgat catgaaacag atatagatgt
     1921 gattttcttt gatccagatt tttcttatga ggaaacctta ttactggaga aaaagctgcg
     1981 agaggatttt cctcagtacc agtgggaatt gaaaaatcag gtctatatgc atcagcacag
     2041 tcctcacact gcttcctata ccagttctcg tgatgctatg agtaagtatc cagaacggtg
     2101 tacgacagtt ggactgcgct tgaatgaaga atcagatttt gaactctatg caccttatgg
     2161 tttggaggat attttgaatt ttcaagttcg tccaactcct catttcttag aaaatgaaga
     2221 ccgaatggaa ctctatcaaa cacgtttatc caagaaaaat tggcaggaga aatggaaaaa
     2281 tttgattttt aaaaatactt aaggaaactt taagctaggg agtgtacact aagttcataa
     2341 gttaagaaga ccttaactta aactcctaaa actttttcat aataatctcc ctataaaaat
     2401 aaagtcgcct aatcaggcgg cttatttttt tgaaaaatgg gcttggtgcc tgagaataaa
     2461 tagcttagtg atagaagaaa atggggaaat atggtataat gaaacgatag atttttgaat
     2521 aggaataaga tcatgtttgg attttttaag aaagataagg ctgtggaagt agaggttccg
     2581 acacaggttc ctgctcatat cggcatcatc atggatggca atggccgttg ggctaaaaaa
     2641 cgtatgcaac cgcgagtttt tggacacaag gcgggcatgg aagcattgca aaccgtgacc
     2701 aaggcagcca acaaactggg cgtcaaggtt attacggtct atgctttttc tacggaaaac
     2761 tggacccgtc cagatcagga agtcaagttt atcatgaact tgccagtaga gttttatgat
     2821 aattatgtcc cggaactaca tgcgaataat gttaagattc aaatgattgg ggagacagac
     2881 cgcctgccta agcaaacctt tgaagcttta accaaggctg aggaattgac taagaacaac
     2941 acaggattga ttcttaattt tgctcttaac tatggtggac gtgctgagat tacacaggcg
     3001 cttaagttga tttcccagga tgttttagat gccaaaatca acccaggtga catcacagag
     3061 gaattgattg gtaactatct ctttactcag catttgccta aggacttacg agacccagac
     3121 ttgattatcc gtactagtgg agaattacgt ttgagcaatt tccttccatg gcagggagcc
     3181 tatagtgagc tttattttac ggacacctta tggcctgatt ttgacgaagc agccttgcag
     3241 gaagctattc ttgcctataa tcgtcgccat cgccgatttg gaggagttta ggaggaaata
     3301 tgacccagga tttacagaaa agaaccttgt ttgcagggat tgccctggct attttcctac
     3361 caattttaat gattgggggc ctcttgcttc agatagcaat cggaatcata gccatgctag
     3421 ccatgcatga acttttgaag ataagaggtc tagcgaccat gacgatggag ggcctcttga
     3481 ctctctttgc aacctttgca ttaaccattc ccttggagaa ttacctgact tttttgccag
     3541 ttgatgggaa tgtggttgcc tatagtgttt tgatttcaat catgttagga acgaccgttt
     3601 ttagcaagtc ttatacgatt gaggatgcgg ttttccctct tgctatgagc ttctacgtgg
     3661 gctttggatt taatgcttta ctagatgctc gtgttgcagg tttggacaag gctctcttag
     3721 ccttgtgtat cgtctgggcg acagacagtg gtgcctatct tgttgggatg aactatggga
     3781 aacgaaagtt agcaccaagg gtatcgccta ataaaaccct tgagggtgcc ttgggtggta
     3841 ttttaggagc aattttagta accattatct ttatgatagt tgacagtaca gttgctcttc
     3901 catatggaat ttacaagatg tcagtctttg ctattttctt tagcattgct ggacaatttg
     3961 gtgatttact agaaagttcg atcaaacgtc attttggtgt taaggattct gggaaattta
     4021 tccctggaca tggtggtgtt ttggatcgtt tcgatagtat gttgcttgta tttccaatca
     4081 tgcacttatt tggactcttt taatcaaaag acggaggaaa cgctatgctc ggaattttaa
     4141 cctttattct ggttttcggg attattgtag tggtgcacga gttcgggcac ttctactttg
     4201 ccaagaaatc agggatttta gtacgtgaat ttgccatcgg tatgggacct aaaatttttg
     4261 ctcacattgg caaggatgga acggcctata ccattcgaat cttgcctctg ggtggctatg
     4321 tccgcatggc cggttggggt gatgatacaa ctgaaatcaa gacaggaacg cctgttagtt
     4381 tgacacttgc tgatgatggt aaggttaaac gcatcaatct ctcaggtaaa aaattggatc
     4441 aaacagccct ccctatgcag gtgacccagt ttgattttga agacaagctc tttatcaaag
     4501 gattggttct ggaagaagaa aaaacatttg cagtggatca cgatgcaacg gttgtggaag
     4561 cagatggtac tgaggttcgg attgcacctt tagatgttca atatcaaaat gcgactatct
     4621 ggggcaaact gattaccaat tttgcaggtc ctatgaacaa ttttatctta ggtgtcgttg
     4681 ttttttgggt tttaatcttt atgcagggtg gtgtcagaga tgttgatacc aatcagttcc
     4741 atatcatgcc ccaaggtgcc ttggccaagg taggagtacc agaaacggca caaattacca
     4801 agattggctc acatgaggtt agcaactggg aaagcttgat ccaagctgtg gaaacagaaa
     4861 ccaaagataa gacggcaccg actttggatg tgactatttc tgaaaagggg agtgacaaac
     4921 aagtcactgt tacacccgaa gatagtcaag gtcgttacct tctaggtgtt caaccggggg
     4981 ttaagtcaga ttttctatcc atgtttgtag gtggttttac aactgctgct gactcagctc
     5041 tccgaattct ctcagctctg aaaaatctga ttttccaacc ggatttgaac aagttgggtg
     5101 gacctgttgc tatctttaag gcaagtagtg atgctgctaa aaatggaatt gagaatatct
     5161 tgtacttctt ggcaatgatt tccatcaata ttgggatttt taatcttatt ccgattccag
     5221 ccttggatgg tggtaagatt gtgctcaata tcctagaagc catccgccac aaaccattga
     5281 aacaagaaat tgaaacctat gtcaccttgg ccggagtggt catcatggtt gtcttgatga
     5341 ttgctgtgac ttggaatgac attatgcgac tcttttttag ataatcgagg aatattatga
     5401 aacaaagtaa aatgcctatc ccaacgcttc gcgaaatgcc aagcgatgct caagttatca
     5461 gccatgctct tatgttgcgt gctggttatg ttcgccaagt ttcagcaggt gtttattctt
     5521 atctaccact tgccaaccgt gtgattgaaa aagctaaaaa catcatgcgc caagaattcg
     5581 aaaagattgg tgctgttgag atgttggctc caacccttct tagtgcagaa ttgtggcgtg
     5641 aatcaggtcg ttacgaaacc tatggtgaag acctttacaa actaaaaaac cgtgaaaaat
     5701 cagactttat cttaggtcca actcacgaag aaacctttac agctattgtc cgtgattctg
     5761 ttaaatctta caagcaattg ccactcaacc tttatcaaat tcagcccaag tatcgtgatg
     5821 aaaaacgccc acgtaatgga cttcttcgta cacgtgagtt tatcatgaag gatgcttata
     5881 gtttccacgc taactatgat agtttggata gtgtttatga tgagtacaaa gcagcctatg
     5941 agcgtatttt cactcgtagt ggtttagact tcaaggctat tattggtgac ggtggagcca
     6001 tgggtggtaa ggatagccaa gaatttatgg ccattacatc tgctcgtaca gaccttgacc
     6061 gctgggttgt cttggacaag tcagttgcct catttgacga aattcctgca gaagtgcaag
     6121 aagaaatcaa ggcagaattg ctcaaatgga tagtctctgg tgaagatacc attgcttact
     6181 caagtgagtc tagctatgca gctaacttag aaatggcaac aaacgagtac aaaccaagca
     6241 accgtgttgt cgctgaagaa gaagttactc gtgttgcaac gccagatgtt aaatcaattg
     6301 atgaagttgc agccttcctc aatgttccag aagaacaaac gattaaaacc ctcttctaca
     6361 ttgcagatgg tgagcttgtt gcagcccttc tagttggaaa tgaccaactc aacgaagtca
     6421 agttgaaaaa tcacttggga gcagatttct ttgacgttgc tagcgaagaa gaagtggcga
     6481 atgttgttca agcaggattt ggttcacttg gaccagttgg tttgccagag aatattaaaa
     6541 ttattgcaga tcgtaaggtg caagatgttc gcaatgcagt tgtcggtgct aacgaagatg
     6601 gctaccactt gactggtgtg aacccaggcc gtgattttac tgcagaatat gtggatatcc
     6661 gtgaagttcg tgagggtgaa atttccccag atggacaagg tgtccttaac tttgcgcgtg
     6721 gtattgagat cggtcatatt ttcaaactcg gaactcgcta ctcagcaagc atgggagcag
     6781 atgtcttgga tgaaaatggt cgtgctgtgc caatcatcat gggatgttac ggtatcggtg
     6841 tcagccgtct tctttcagca gtgatggagc aacacgctcg cctctttgtt aacaaaacgc
     6901 caaaaggtga ataccgttac gcttggggaa tcaatttccc taaagaattg gcaccatttg
     6961 atgtgcattt gattactgtc aatgtcaagg atgaagaagc gcaagccttg acagaaaaac
     7021 ttgaagcaag cttgatggga gctggttatg aagtcttgac agatgaccgt aacgaacgtg
     7081 tcggtgttaa atttagcgat agtgacttga ttggtcttcc aatccgtatc actgttggta
     7141 aaaaagcggc cgatggcatt gtagaagtta agatcaaggc aactggtgac accattgagg
     7201 ttcatgcaga taacgtgctt gaaacgcttg aaatcctaag caagaaataa aaactataat
     7261 cagaagaaaa acaaggaaaa aatgtaacta gtttttacct tgttttttct gtataatggg
     7321 agaaatgagt agataaagag gtaaatgtta tgctaagatt tccaaaggat tttgtctggg
     7381 gatcctctac ttctggaccg cagacagaag gacgtgtagc tggtgacggt aagggagaca
     7441 atctctggga ttactggttc caagtggagc caaatcgtta ctataatggg attggttcag
     7501 ataagacatc gactttttat gaaaattggg agcgggatat tgagcttttg ttagagactg
     7561 gtcacacagt ctttcggact tctattcagt ggtcacggat ttttccacaa ggctgtggaa
     7621 aagtcaaccc tcaaggtgtg gatttttatc gtaaggtctt tgaggctatt aaggctaaag
     7681 gaattcgtct gttagtcaat ctctatcatt ttgatttacc ttttgctctt caagaggatg
     7741 gtgatggttg ggaaaataag gcgacagtct cagcctatga agactatgct cgtttttgtt
     7801 ttgagactta tggagattta gtggatcaat ggattacctt taacgagccc atcgttcctg
     7861 tagaatttgg ttatttttat gatgcccatt atccacataa ggtggatgca gaggcagctg
     7921 ttaaggtagc ctatcataca caattggcca gcagccgggc tgttaaggct tgccatgaac
     7981 ttttgcctga ttccaagatt gggattgtcc tcaacttgac accggcttat ccacgtagcc
     8041 agcatcctgc tgatgtcaag gcagctcgta ttgcggccct ttttcaggcc caatctttct
     8101 tagatccatc tgtcttgggg acttatccac aggagttggt agaaatcttg catgaacacg
     8161 gtcttttacc tgatgctaca gaggaagagt tggaactcat tcgtgataat acggtggact
     8221 tccttggtgt gaactactat caacctttgc gtgttatggc tcctcgattt gctaagcatc
     8281 cagatagtcc actcttacca gaacattttt acgagcctta tgtgatgcct ggacgtaaaa
     8341 tcaattctca ccgtggttgg gagatttatg agcaagggat ttatgacatc gcccaaaata
     8401 tcaaggaaaa ttatggcaat attgagtgga tgttgactga gaatggtatg ggtgttgaag
     8461 gggaagaaaa attccgtcaa gatggaatga ttcaagatga ttaccgtatt gactttgtaa
     8521 aaggtcatct tcgtgaactt caccgtgcca ttgaagatgg tgccaactgt aagggctact
     8581 tgatttggac ctttattgac tgctggtcat ggctcaacag ctataaaaat cgctatggtt
     8641 tggtcgaatt agacttggaa acgcaagaac gtcgtctgaa gaaatcaggc cactggttca
     8701 aagaattaag cgataataat ggattttaaa aaggactctg actgattatc ccaatcggtc
     8761 agagtttttt gcttacagga gcttaatttg aactatacca atttttactc ttgacaagtg
     8821 aaagaaacaa gtatatactg tttttgctga ttctataaaa gatgaattag actataccaa
     8881 ttttaaggag aaagcacagc ttgcctgtgt cgtatatact atgtgtggaa ttgttggtgt
     8941 tgttggaaac acaaatgcaa ctgatatttt gattcaaggg cttgaaaagc ttgaataccg
     9001 tggctatgat tctgcgggaa tttttgtcct agatggtgct gataaccatt tggtgaaggc
     9061 tgttggtcgt atcgcagaat tgtctgccaa gacagctggt gttgagggaa caactggtat
     9121 cggacatact cgttgggcaa ctcatgggaa accaacggaa gacaatgctc acccacaccg
     9181 ctctgagaca gaacgttttg tcttggttca caatggggtg attgaaaact accttgaaat
     9241 taaagaagaa taccttgctg ggcaccactt caaagggcaa acagatacgg aaatcgccgt
     9301 acatttgatt ggaaaatttg cggaagaaga cggtctctca gttcttgaag cctttaaaaa
     9361 agctcttcat attatccgtg gttcatatgc ctttgccttg attgactctg aaaatccaga
     9421 tgtcatctat gtagcgaaaa acaaatctcc acttttgatt ggtcttgggg aaggctacaa
     9481 tatggtctgc tcagatgcta tggctatgat tcgtgaaacc aaccaataca tggaaattca
     9541 tgaccaagag ttggtaatcg tcaaggctga tagcgtggaa gttcaagact atgatggtaa
     9601 cagtcgtgaa cgtgctagct atactgcgga acttgacttg tcagatatcg gtaagggaac
     9661 ttatccttac tacatgctta aggaaattga tgagcaacca actgttatgc gtaaactcat
     9721 tcaagcctac acggatgatg ctggtcaagt agtgattgat cctgctatca ttaaggctgt
     9781 tcaagacgca gaccgcatct acatccttgc agctggaaca tcttaccatg caggatttgc
     9841 ttctaagaaa atgttggaag aattgacaga tacaccagtt gaacttggca tctcatctga
     9901 gtggggctac ggtatgccac ttctcagcaa gaaaccactc ttcatcttta tcagccaatc
     9961 tggtgaaaca gcggatagtc gtcaagtttt ggtcaaggct aatgaaatgg gaattccaag
    10021 cttaacagtg acaaacgttc caggttcaac cctctcacgt gaagccaact ataccatgct
    10081 ccttcacgca ggtcctgaaa ttgccgtggc atcaactaaa gcctatacag cgcaaatcgc
    10141 agcccttgcc ttccttgcaa aagcagtcgg agaagcaaat ggtaatgcta aagcgcaagc
    10201 ctttgacctg gttcatgaat tgtcaatcgt agctcagtct atcgaatcaa ctctttcaga
    10261 gaaagaaacc attgaagcca aggttcgtga acttcttgaa acaactcgta acgcctttta
    10321 catcggacgt ggtcaagatt actacgtagc catggaagca agtctcaaac tcaaagagat
    10381 ttcttatatc cagtgtgaag gttttgcggc aggagaactc aagcacggaa ccattgcctt
    10441 gattgaagaa ggaacacctg tcttggctct cttgtcagat ccagtccttg ccaaccacac
    10501 tcgtggaaat atccaagagg tggcagcccg tggtgctaag gtcctcacta tcgcagaaga
    10561 aaatgttgct aaagataccg acgatatcgt ccttacgact gtacaccctt acctctcacc
    10621 aatttcaatg gtcgtaccga cgcaattggt tgcttacttt gcaaccctcc accgtggcct
    10681 cgatgtggat aaaccacgta accttgctaa atcagtaacg gtagaataag ctaaaaaagt
    10741 ctagttatct aggctttttc taatgagcaa attggttgct tgtactcaag attcgtgtta
    10801 gaataatttt tcaaattgaa ggacagagat agacaaggag aatcacaatg gtagaattgg
    10861 gaatttcaac atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg
    10921 ctgaacgcat tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggacg
    10981 tatatgggat tggcgagcac catcgggcgg attttgcagt atcagcccca gagattgtcc
    11041 tggccgctgg ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt
    11101 caagcatgga tccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg
    11161 gacgatcgga gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt
    11221 atgacttgaa agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca
    11281 atgaaaagac caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag
    11341 tttatcctcg cccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg
    11401 aatcaacagt gaagattgct caggctggtc taccgattgt atatgctatt attggtggta
    11461 atccacgtta ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggcc
    11521 atgctgacaa agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg
    11581 agcaggcggt gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag
    11641 accgtccgca ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg
    11701 gcgccatgtt tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg
    11761 atttaggatt ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg
    11821 ttctgagagc tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg
    11881 ctatgaaaga ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac
    11941 aaaaattaat cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag
    12001 ttctcttttt tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct
    12061 gcaaatagga gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct
    12121 ggggttgcag gtatattttc cttgctagag ttttctaccg attcgtttcg aaccgcttct
    12181 tttacagatg cttcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct
    12241 tggctaggtt tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta
    12301 gcttctggag ctgggtcttg atgtgcaggg tgagaagctt cattttgatg ttcaggcttg
    12361 gaaggggttg agtctggttt ctcttctgca gttgactcat ggctagttcc attttgagag
    12421 actcgaagaa cagtagctgt aagggcattc aatttcaagc ctttttcagt ccattcaagt
    12481 cctttcgggt tggcaatttt gactgatcct gcttggtttt catctgccaa aacttccgca
    12541 tttcttagat gtgcaaaggc agttcccaaa ttaaattcgc gagctttttc atccgcattg
    12601 acaaagactg cgtagatatc gccgtttgga gcagtgattt ggtagccaat cactacatcc
    12661 tctttttcca caccattttg gcctgggaca gtgatgaggt ggacacggtc tttgatatct
    12721 tggagactct taagtcggaa ggcatctgta gattgacgaa gggcaatcaa acctttcata
    12781 tagtcacggc tcttgacatt ttcaggataa gctttaccat ctgtagcctt agtccagtca
    12841 aacttgttga ctgcgtcgct agaatcgtaa gaatcatgga tgaagtaagg atagtcaaat
    12901 gggttgccgt ccttatcacg caacaagtga gatttgtttg gaaccttatc ctctgctact
    12961 ggagtcttgt aggctgggtc acggaattgt ttagtacgtc catattcctg accggagtgg
    13021 ataaatggag ttccttgagc tgtcaagacc atgagatttc caagtcgtaa acgacggtgg
    13081 atttcagcat agttctcagc cttgcttggg tcttttttga tagactgggc aatgatgtca
    13141 aagagggtca agttatcatg ggctgctatg tattggatga catctccagg gctgtcagct
    13201 tcaaagttag ttggttgagc aatgagattt ttaaagatgg tgttgacatc acgcttgcca
    13261 cctgtgataa aggcaggttg accttcgttt ggataaccag atttgaggtt gttacggatg
    13321 tcatctgaaa agacagcgac agtatcggta tgtttcatcc aatcttggtc agcagcttta
    13381 gtaggcatgt tttcatcacc ggcataggtt ctccaacctt caccaagcat gatgaggttt
    13441 ggattgaggg cgcgtgcagc cttgtaagct tcttcgatag aagcggcgtc atggtctccc
    13501 atcatatcga aacggaatcc atccactttg taggtatcaa ctaggtattt gatagagtca
    13561 actaggagcc gtttggtcat atggtgggtt gttcccaagc gtccaccacc aaagctagtt
    13621 cgaggtgtgc catcggcatc cataaagtgg tagtagtttg gctctaggtc ttcaaagata
    13681 tcgactttgg ctgtgtggtt ataaacgaca tctaggatag ctcccatacc acgtttgtgg
    13741 atttcgttga tgaggttttt aaattctgcg attcgttttt ctggattctt aggatcgctt
    13801 gagtacatac cagtcaagga gaagtagttt tgagggtcat atccccagtt gtagttgctg
    13861 ttgcttgaag cgtagtcaga caagcgttca tggtttttca attcattgac aaagtagtaa
    13921 gacaagactg gaaggagctg gatatgggtt acacccaagt ctttgagata gtctagtttt
    13981 tcaatgaagg cttcaaaagt cccaaatggt ttggtcaagt cttttgcaat ggcaggatct
    14041 gaagtgaagt cacgcacatg agcttcgtag ataacggcgt cttcacgagt cttgaaattg
    14101 tgaatcttac cataagtcaa gtcttgaggt ccgagtttag ctggatctac aaaggcggct
    14161 ttagccactt tatgggtatc gtcaattttg gcatcgtcgc tattccaagc agcaagagat
    14221 ttagcgtaag gatcgagtgc aagaacagtt ttaccttgac gctcgatttg gtattgataa
    14281 tagtagccag tgaaatctgt gattccgagt ttgtttgtgc tgtctagagt ttgtttccaa
    14341 gttcctcttt cccctttttc gagagcgaca gttccaacta ctttgtcagg gtcattcttg
    14401 tcgtagacaa caacagaaac cttatcagca cttggtgacc aaagggtcaa atcaacttgt
    14461 tttccttctt cttttaggtc agctcccagt ttgccatcat agctgtatgt ctcatctttc
    14521 aggtgccagc ttgttttggt agtgaattgg tcggaattgt agctaacagt ataagggtgt
    14581 tttgtgtcag agaaatctcc gctgtaggtc actttcttac cagcttcatc gattgcaaca
    14641 tcggtaatag ttaccttgtt tcctaggtga ttagtgatgt tggagtgttt gaggatatct
    14701 tcttttttag caccgacaag tgttgaaaag ctactttcaa tgctagaagt gcctacgtgt
    14761 tgggctcctg tcatacggat atcatggaca tagtatggat ttgtgtaaat cgattcatca
    14821 tcgtctttta ggaaaatttg gctatgattt ttcaaatctg tgaacttata attttcttta
    14881 cggattttca cgtcgtctcc ttgtttgctc tcatctagta ataaaaatcc aaattctctt
    14941 gcggcttcat taagaggaat gtcgatatag cggccatatt tgcctgtagc cgtaaagtct
    15001 gttccgtcag gccattgagc gctacttgga tttttcacat ctccccagta ccagagagat
    15061 ttcttgtcat agttgccatc tgtgcggtag tagttgacgc gaacagttcc tgcaggctgt
    15121 ggctcgtaag agaaaacctt gtaatcttgg tctaaccaag cttcgttcat ttttggaact
    15181 agtttttcta cagatttatc gccggttaga ttttttccag ctgtattgtt gatgaggaag
    15241 ctaattttct tggcttgttc tccctttaat ttgacatcta ggtaatagcc gtagtcatct
    15301 ttcttggcat ccttgaagga caaagctccg tttggccagt tttcagatgg tttttcaaca
    15361 tcgtcccaag tccatagtcc ttgagcatcc ttgttttctt caggaagttt tttgacatgg
    15421 atacggaagt agttatcttc gatgggctct tctgccttag tttcagttgt tactggacta
    15481 gtagaagtag ttggctctgt tgcaggtttt tcttctgttt tctctaggga agcgtttgca
    15541 tttctaggtg aagaaatatc actttcgttc ttaccagagc cagctgctgt atcagtaaga
    15601 ggttgggcaa gggtggttgt atttctgttg ttgggttcgt tagtggttgg tgtactttcg
    15661 tcggatgaga tagttggtgt agccatggca agcaagacaa ggcttgcgcc gataaggaca
    15721 gaaccagttc catttttgag ggaacggatg ctgtagacca tttttttctc agtgtgagat
    15781 ggtgtttttc tcataatgat tctccaatca ataaatttct atatcagtat agcatgtagt
    15841 aaaacaatat gcaagcgttt tctttgattt gtgaaaaaat tcttactttt gagaagtttt
    15901 ctgtactatt ttatatatca gtataaatga cggagataaa aatgtcacat aagccaagcc
    15961 gtattattag gaagatgatg tgttcccagc tatttttatt cagaaattga tctctaacat
    16021 taccaataaa aaagaaaaat atcttgacaa gcaagggaaa attttgttac aataatagac
    16081 ggtacttttt acttttggtc tctcaagagt gtacagggac gtgctgacaa atgttgcaaa
    16141 agtacacaca gatgatatct gtcaccaagt gtatcatcac caaaaataaa aaaacacagg
    16201 agaatgtaga tgcctacaat taaccaattg gttcgcaaac cgcgtaaatc aaaagtagaa
    16261 aaatctaaat caccagcttt gaacgttggt tacaatagtc ataaaaaagt tcaaacaaac
    16321 gtttcttcac cacaaaaacg tggtgttgca actcgtgttg gaacaatgac acctaaaaaa
    16381 cctaactcag cccttcgtaa attcgctcgt gtacgtttga gcaaccttat cgaagttact
    16441 gcctacatcc caggtatcgg acacaacttg caagagcaca gcgtggtgct tcttcgcggt
    16501 ggacgtgtaa aagaccttcc aggggtacgt taccatatcg tccgtggtgc acttgatact
    16561 gcaggtgtta acgatcgtaa acaaggccgt tctaaatacg gtactaaacg tccaaaagca
    16621 taaggaaagg ggataaagag aaatgagtcg taaaaataga gctccaaaac gtgacgtatt
    16681 gccagatccg ctatacaatt cacaactagt tactcgtctt atcaaccgcg ttatgcttga
    16741 tggtaaacgt ggtactgctg cttcaatcgt ttacggtgct tttgagcaaa tcaaagaagc
    16801 tactggcaac gatgcacttg aagtatttga aacagctatg gaaaacatca tgcctgtact
    16861 tgaagtacgt gcacgtcgtg ttggtggttc taactaccaa gtcccagttg aagttcgtcc
    16921 agaacgtcgt acaacacttg gacttcgttg gttggtaaca atcgctcgtc ttcgtggtga
    16981 acacacaatg caagaccgtc ttgcaaaaga aatcttggat gctgctaaca acactggtgc
    17041 agcagttaag aaacgtgaag atactcaccg tatggctgaa gctaaccgtg cattcgcaca
    17101 cttccgttgg taagatagga tgcgaaagcg ttaagaaagt cccagagaaa atagggaatc
    17161 gaagcaggtt gcggttgcaa ccaatgagat tcatcttttt ctccagactt ttagcttgag
    17221 ctcaactaaa tcatgatgct aggcacggaa ggatgcaagg tgaaaatagg aaactgacgc
    17281 agtattcaac gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca
    17341 tcggctaact aactttagcc tgggttcaaa ttagctaaat cgattagtat tagctataac
    17401 tcagcttacc atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag
    17461 gtcctgccta tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat
    17521 aggagaaaca aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat
    17581 catggctcac gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg
    17641 taaaatccac aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca
    17701 agagcaagaa cgtggtatca cgatcacatc tgctgcgaca acagctcaat ggaacaacca
    17761 ccgcgtaaac atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc
    17821 tcttcgtgta ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgaacctca
    17881 aactgaaaca gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa
    17941 caaaatggac aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct
    18001 tcaagcaaat gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat
    18061 cattgacttg atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct
    18121 tgaagaagac atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat
    18181 tgaagcagtt gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat
    18241 cactaacgaa gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc
    18301 agtattgtgt ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat
    18361 cgactacctt ccaagtccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga
    18421 cgctgaagaa actcgtccag catctgacga agagccattt gcagctcttg ccttcaagat
    18481 catgactgac ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca
    18541 atcaggttca tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct
    18601 tcaaatgcac gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc
    18661 tgccgttggt ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat
    18721 catccttgag tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc
    18781 taaagctgac caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac
    18841 attccgcgtt gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact
    18901 tcaccttgac gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg
    18961 tgctcctcaa gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt
    19021 caaacgtcag tctggtggta aaggtcaatt cggtgatgtg tggattgaat ttactccaaa
    19081 cgaagaaggt aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga
    19141 atttatccca gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg
    19201 ttacccaatg gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc
    19261 atctgaaact gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc
    19321 acaaccagct atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct
    19381 tggtgatgtt atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca
    19441 cggtaacagc caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac
    19501 agttcttcgt tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga
    19561 agatgtacct aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc
    19621 cgtcctcact ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct
    19681 aaatatggta aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa
    19741 ttttgatgaa tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg
    19801 ccaatattga gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat
    19861 tttctaatat tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat
    19921 tttctaagac aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa
    19981 atcagctctt gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag
    20041 gttttaagtc cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg
    20101 aaggatctga agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca
    20161 aacaacttga aaagtttggt tttccaactt ttaactgtca agttgagaag aatgatgtcc
    20221 tgacccaaga gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca
    20281 atgaggaagc gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag
    20341 agaaaccagt ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg
    20401 cggagattac tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg
    20461 ttgtttttga tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa
    20521 tgacggacta tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc
    20581 agaagtttga cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga
    20641 ataacttcac acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg
    20701 agcggaagga tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca
    20761 tgtcgactat ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg
    20821 gacacaaggc ggttgctatc acagaccatg ggaatgtcca gtcctttcca catggctata
    20881 aggcggctaa gaaagcggga atccagctga tctatgggat agaagccaat atcgtggagg
    20941 accgtgtccc tatcgtctat aacgaagtgg agatggactt atcagaagca acctacgtgg
    21001 tctttgacgt ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg
    21061 cctctaagat gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc
    21121 atcccttgtc agcttttact acagagttaa ctggaattac agatgatcat gtcaaaaatg
    21181 ccaaaccact agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag
    21241 ttgcccacaa tgctgccttt gacgttggct ttatgaatgc taattatgag cgtcatggtc
    21301 ttccaaagat tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg
    21361 agtataaacg ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc
    21421 accacatggc caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag
    21481 aggtagcaga aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc
    21541 cagattctta caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag
    21601 gtctaaaaaa tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc
    21661 cacggattcc gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct
    21721 gttcagaggg tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg
    21781 tggccaagta ttatgacttt atcgaggtca tgccaccggc tatctatgcg cccttgattg
    21841 ctaaagagca ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg
    21901 ttggagaccg ccttggcaag cctgttttgg ctacgggaaa tgttcactat atcgaaccgg
    21961 aagaagagat ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaacc
    22021 gaactatcgg tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa
    22081 cgactaatga gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg
    22141 ttattgaaaa caccaatgcc ttggcagaaa tatttgaacc cgttgaagtc gttaagggtg
    22201 acttgtatac gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga
    22261 aagcttttga gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag
    22321 aattaacatc catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg
    22381 tgcaacgttc taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt
    22441 tcgttgcgac catgattgga attacggagg tcaatcctct ctctcctcac tatgtctgtg
    22501 gtcagtgtca gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc
    22561 cccataagga ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt
    22621 ttgagacctt ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg
    22681 gagaagatca gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct
    22741 tccgtgcggg aacagttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt
    22801 acgagcgaga ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag
    22861 cggcgggtgt caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact
    22921 acatggatgt ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat
    22981 ggcagaccac tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac
    23041 tgggacatga tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta
    23101 ataaaattcc tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtgctag
    23161 gggtaacacc tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa
    23221 caaatttcgt acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc
    23281 agctgtctgg tctgtcccac ggtactgatg tttggttggg gaatgctcag gatctgatta
    23341 agcaaggaat agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc
    23401 tcatgcatgc gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg
    23461 gtttgtggct aaagatttca gaagaggaga gaaatggcta tatcgaagca atgaaggcta
    23521 ataaggtgcc agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg
    23581 cccatgcggc agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc
    23641 ctatttatta ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca
    23701 tgggtgcggg cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga
    23761 acaatgaagc ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga
    23821 tgtgggaacg aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt
    23881 tcctcatcga cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga
    23941 acgttgccaa gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac
    24001 tacgcaagcg tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc
    24061 ttggaaatat gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg
    24121 cttaataatc tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt
    24181 ttgttaaaat agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg
    24241 tctggatagt gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat
    24301 gacaacagct attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga
    24361 tgttagacta gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg
    24421 taatatgagc cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga
    24481 ttcgttatca taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg
    24541 cagaattatt agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat
    24601 atcgtgatca ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc
    24661 agccagattg gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga
    24721 ggacaggcag tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag
    24781 aatatttgcg gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga
    24841 tcgtacaatt cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt
    24901 ttctgctttg aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt
    24961 taaagaaaat ctagaaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc
    25021 tggtcacact ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt
    25081 gaaagaagct tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat
    25141 taaccgtgag aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa
    25201 gattgctgag atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc
    25261 tgatccaggt gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat
    25321 gggacttgcc atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt
    25381 agcagccgct gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga
    25441 agaagcagtt gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga
    25501 tcctgttaag gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa
    25561 taaggagcaa ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt
    25621 gccaaagaac cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt
    25681 gccaaatatg ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta
    25741 tgtcacttct acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac
    25801 ctttaaggat ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga
    25861 ccttgtcttt gaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc
    25921 aagtccaatt tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc
    25981 aaaccacttg gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag
    26041 cgaagaggag cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat
    26101 tggttctaac caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt
    26161 ccgtaatggg aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct
    26221 cctagtggga tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg
    26281 aaaaatgttt ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg
    26341 gccagtttta tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc
    26401 tattttttgg agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag
    26461 caaactagga aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact
    26521 gacgaagtca gctaaaaaca ctgctttgag gttgcagata gaactgacga agtcagctaa
    26581 aaacactgct ttgaggttgc agatagaact gacgaagtca gctaaaaaca ctgttttgag
    26641 gttgcagata gaactgacga agtcagtaac atatatacgg caaggcgacg ttgacgcggt
    26701 ttgaagagat ttttgaagag tatgaaacga aaaggaggtt ggtcattgta ctagcctcct
    26761 tttgatatga tataatagtt ctatgagatt agataaattt ttagttgcct gtgcggtggg
    26821 aagtcggact gaggtcaaaa acttgctcaa ggctgggcgc gtgactgtaa atggtaaaaa
    26881 agaaaaatca gctaaattgc agattgatga aaaaatagat gagattcgct ttgatgggca
    26941 agtgttggag tatgaagagt ttgtctacta catgatgaac aagcccaaag gagttatctc
    27001 agcgactgag gatcccaagc acagaaccgt tctggacttg ttggatgact tggcgcggag
    27061 taaggaagtt tttccagtag gacgcttgga tattgacacg catggtcttt tgctcttgac
    27121 caataatggt cagctggctc atgttcttct ttcgcccaag cgtcatgtgg acaagactta
    27181 tcaggctcag gtcaagggaa ttatgaccca agaagatgtg gagacattta tcaagggcat
    27241 tccgctcaaa gactttacct gtcagcccgc tagactggag attctttcca cagatgcaga
    27301 aaagaatcag agccaaatcc gtgtgaccat tgcagaaggg aagtttcatc agatcaagcg
    27361 tatggtgggc tactgtggca aggaagtggt ggacttgcaa cgattgacta tgggaacttt
    27421 agtattagat gagaacctgg aacgagggga atggcgtcgc ttgaccaagg aagaattaga
    27481 aattctccgc gctaatatta tttaatttag tttaatactc aatgaaaatc aaagagcaaa
    27541 ctaggaaact agccgcaggc tgtacttgag tacggcaagg cgacgttgac gtggtttgaa
    27601 gagattttcg aagagtataa attcgaaaaa ggtgagggag aatgtcctta ccttttatgt
    27661 tttttagttg cttcctttgt gaaaagagtt ataatagact gtagaataaa aggaggaatc
    27721 tatgaacgcg attcaagaat catttactga taaactattt gccaactatg aagcaaatgt
    27781 aaaataccaa gcgattgaaa atgctgccag ccacaacgga atttttgcag ctctggaacg
    27841 tcgccaaagc catgtagaca acacacctgt tttctcattg gatttaacca aggacaaggt
    27901 cactaaccag aaagcgtctg gtcgttgctg gatgtttgcg gctctcaaca ccttccgcca
    27961 caaactcatc tcgcaataca aattggagaa ctttgagttg tcacaagccc acactttctt
    28021 ctgggataag tatgagaaat caaactggtt cttggagcaa gtcattgcga cttcagacca
    28081 agaattgact agccgcaagg ttagcttctt actccaaaca cctcaacaag atggtggtca
    28141 atgggatatg gtcgtttccc tctttgaaaa atacggtgtc gtgcctaagt cagtttatcc
    28201 tgagtctgtt tcatctagca gcagtcgtga gctaaatgcg atccttaata aattgcttcg
    28261 tcaagatgct caaatcttgc gtgatttgct tgtttctggt gcagatcaag tgactgttca
    28321 agctaagaaa gaagacctct tgcaagaaat ctttaacttt cttgctatgt cattaggact
    28381 tccaccacgc aagtttgact ttgcttatcg cgataaagat aacaactaca aaagtgaaaa
    28441 aggaatcaca ccacaagagt tctacaagaa atatgtcaat cttcctttag aagactacgt
    28501 ttctgttatc aatgctccaa ctgctgataa accttacgga aaatcttaca cagttgagat
    28561 gttggggaat gtggttggta gccgtgcagt tcgttacatc aacgttccaa tggagcgctt
    28621 gaaagaattg gcgattgccc aaatgcaagc aggtgagact gtttggtttg gttctgatgt
    28681 cggccagctc agtaaccgta aggctggaat ccttgcgaca gatgtttatg actttgaatc
    28741 aagcatggac attaaactta ctcaagacaa ggctggacgt ttggactata gcgaaagctt
    28801 gatgacccac gccatggtct tgacaggtgt tgacttggac gaaaatggta aatcaaccaa
    28861 gtggaaggtt gaaaactcat ggggagacaa ggtcggtaca gatggttact ttgttgcctc
    28921 agacgcttgg atggacgaat acacatacca aatcgttgtt cgtaaggaat tgctgacagc
    28981 agaagaacaa gctgcctatg gagcagaacc aattgtactt gcaccatggg atccaatggg
    29041 agccttggct aaataaaagc atagaaaaaa ggaatcagat tttagaacct ggttcctttt
    29101 tagttgcttg attacatgat gtgaagaaca tgtgccacaa tacccactgc gaagagggca
    29161 aggataatag tgattggaga tacttttttc ttaagtaagt acatgcaaag taaagtaagg
    29221 agtagtcctg ataatccagg aatcaacata tccaagtttt gttggaaagt agtaactttt
    29281 tcaggagttt gagacaatcc ttgtcctact tgtgcgaatg cttcttggat acctttagac
    29341 ccttctggca atttatccca atggatataa gccttttcat ctagttgaac tttagaaaca
    29401 tcgaaagcaa atttaatatt tacccagcgt tgaacaagga cagcaagaat gaacatccca
    29461 aggatagaag ctcctttagt gatatcttga aggataccac cagacatatc tttagtgatt
    29521 tctgatccag ccttgtatcc aatctcttga acataccaca agaatgacat acgaatcaag
    29581 ttccatgcaa caaagaagag gagtggcccc aagatattgc cagtaagggc aagtgaagca
    29641 ccgagagatc caaggattgg gcgtactgta aaccagaata ctgggtcacc gataccagca
    29701 agaggtccca tcataccgat tttaacccct tggatagcag cgtcatcgat ttccacaccg
    29761 ttagcacgtt cttcttcaag cgcaagagta acccccatga ctggagcagc tacgtatgga
    29821 tgagtgttga agaactcaag gtgacgctca agagcagcga tttgatcttc ttttttagta
    29881 tagagttttt tgatagctgg aatgagtgta taagcccagc ccaagttttg catccgttca
    29941 aagttccaag acccttgtaa gaaggttgaa cgccaccaaa cttttttacg atctgattta
    30001 gttaattgaa gtttttcagt catgatgttt tcagtccttt cttatcttag tagtcttcta
    30061 ggatatcgcc gattgggtcg ttagaagttg cggctcctcc gccaccattt ccaccagttt
    30121 tagaaaggtg aaggtagata agagcgatag caacaccgat agcaccgaat ccgattagag
    30181 taatatctga cacagcagcg agaacgaaac caagagcgaa gaatggccat acttcacgag
    30241 ttgccatcat gttgataacc atggcgtaac caacggcaac gaccatacca ccaccgatag
    30301 ccataccatc tttgagccag tctggcatgg cactaaggat actttgtaca gtttcagttg
    30361 gtaccataag gagaagagct gcaggaagcg cgatacgaag tccttggaag agtagcgcaa
    30421 tgaaatgcgc acgctccaca gcgccgaagt cacctttttt agcggcagca tctgcagtat
    30481 gaaccaaacc aactgaaatt gtacgaacaa tcattgtcaa gaaaagtcca gctacggcaa
    30541 gagggatagc aaccgcttgg gcaacaccga taccagtctt ggtaaagtca ccaccaagaa
    30601 ccatgataat ggcagcagcg acagaagcaa gtgcagcatc aggagcgata gcagcaccga
    30661 tatttgacca accaagggca atcatttgaa gcgatccacc gaggataatc cctgcttcca
    30721 agtgacctgt tacaagccca ataagggtac aggctacaag tggttggtga aattggaact
    30781 ggtcgaggat gccttcaaga cctgcaaaga aggctacaac gactactaaa accatagaaa
    30841 taatagacat gtttaaaatc ctttcataaa taatggctta tttgacattg gctttgttaa
    30901 tcaagtcaaa caaatctttt ttagaatcat ttggtacttt acggacatca aattcaacac
    30961 ccaagtcacg cattttttca aatgtagcaa catcttcttt gtccatagac aaaacggtat
    31021 tgaccaatgt tttacctgtt gagtgagcca tagaaccaac gttaagagtc ttgattggca
    31081 cgccgccttc gatggcacga agggcatctt gaggtgtttc aaacaagata agggcatgtg
    31141 tttctccaaa acgtgggtct tttgaaatct caatcagttt ttgaattgga accacgttag
    31201 ccttgacatt acctggagct gcttgtttaa tcaattcttt acgaaggtcg tctttagcca
    31261 cgttatctga agcaacgatg atacgatttg cttttgaatc tggagtccaa gcagttgcaa
    31321 cctgaccgtg aagtagacgt gtgtcaagac gggcaagatt gattttcaat ttaccgtctc
    31381 cgataacagt tccttctggg atagcagttt gggcaactgg agcagctgca gcgcttgcaa
    31441 cttcttcaac tggatttagc tcttctggaa gagctttgat gccatctttg gcttctttaa
    31501 tgatattagc agcgactttt tctacacctg cagcagcgtc catgaggcgc tctgtgtagg
    31561 cttgaatcaa catcggtaag ttaagtcctg tgatgatggc aaacttacgc tcaggatttt
    31621 ctcccatcac gcgactagct tggttaaatg gagaaccact ccaaaggtca gccaaaacta
    31681 gaacctcatc ttctgcgtca aatgcagcaa cagcgttatt aaacttagcg tatagatcat
    31741 caggaccttc atttggcata aaggtcacaa cttgaacctt ttcttgttca ccaaagatca
    31801 tagatcctga ctgatgaata cccgcagcaa attcgccgtg gctcgcaata atgattccga
    31861 tactcattat tgtcattcct ccttttttgt tttagttttc atttaagaaa actttaagac
    31921 tgtttaagta taaaccgttt tcataaaaaa agcaactatt tatcataaaa aattaaaaaa
    31981 tttttatttt tgtatgttga tatgttgagt ttttgaggag taatcttgaa ttcttattta
    32041 aaatttaata taaaaaagtt ggaagaagct tccaactttt aaaataggtt tctattagat
    32101 tagtgggtga agtcgagtac catacgtcct tggatttggc ctttttccat ttcgtcgaaa
    32161 atggcaacag catcttctac tggacgtttt tgaacaactg ggactaccag accttctgca
    32221 ccaaattgga aggcttcttc taagtcttta cgagttccga caagagaacc gatgacttgg
    32281 attccatcga ggactgtttt aacgatgctg agttccatca tttcagaagg aagaccaaca
    32341 gcgacgacgc gaccaccagc acgaatggag tcaacagcct ggttgaaggc aactttagac
    32401 acagcagtta cgacagctga atgagctcct ccatcagttt tttctttaat gagtccagct
    32461 acatcttcaa cttcgaggcc gttaatcaca atgtcagcgc ctacttcttt tgcaagggca
    32521 agtttgtcat tgttgatatc gactgcgata acatgagcat tgaatacttt tttagcgtat
    32581 tgaacagcga ggttaccaag tccaccagca ccgtaaagaa cagcccattg gcctggttca
    32641 acttttgctt ctttgatagc tttataggtt gttactccag cacatgtgat agaagaagct
    32701 tgggctggat caagtccgtc aggaactttg acagcatagt cagcagttac gatacattgt
    32761 tcagccatac caccgtctac tgagtagcca gcatttttca ctgtacggca aagggtttcg
    32821 cgaccagttg tacagtattc gcaagtgcca catccttcaa agaaccaagc aacgctgacg
    32881 cggtcaccga ctttaaggct tttcacatct ggagcaatct ctttaacgat accgatacct
    32941 tcgtgcccaa gaacacgtcc tgggacttga ccaaagtcac catgagcaac gtggaggtcg
    33001 gtgtggcaaa cgccacagta ttcaacttct acaagtgctt ccccagtttc aagtggacgg
    33061 agtacttttt cttcaatagc aacaccagtg ctttctggat ttacaacaac agctttcata
    33121 gctatcctcc ttgatattga ccgagaacag ggacaacggg actggattga ttttttgtca
    33181 acagagtcga gtgtgacgag ctctcttgta tttatatgtg aagtatatca caaaagaaag
    33241 ccttttccaa ggttttggag acaaaaagta gaacaatcga ttaactggtt gatgagactg
    33301 tgaaaagagc acaaagacca gcttgcaagc tggtcatact cttcgaaaat ctcttcaaac
    33361 cacgtcagct tcatctacaa cctcaaagca gtgctttgag caacctacgg ctagcttcct
    33421 agtttgctct ttgattctca ttgagtatca gtataggtta taagaataag ttataagaat
    33481 aagtcttgta gggttttggc aaccccatct tggtcgttgg taagggaaat ttgctcatct
    33541 gcataaggga gtagctctgg attggcattt ttcatggcat aacccttccc agcaaaagcg
    33601 agcatttcgg tatcattgtg ttcatctcca aaggcaatca aatctttttt gtcacgattc
    33661 attatcttga gcaagtagtc caaagcaaag gccttgttga caccttttgg ggtacattca
    33721 aggatattga gcggacctcc ccaggtattg atagaaagtt gatgctggta gaaggcgttc
    33781 atttcttttg ccaaggcata tttgtcactg gctctggtct gcaagaggat acagttaggg
    33841 tccttggtca ccaattcagg ctggaattga tcttcaggct ggaaagcttc tacaccaaat
    33901 agtttgggat tggcaatttc ttcattggga tttgtaatgt agaatttttt acgatattct
    33961 ccagcgataa aatcggcttg aatgtcctct gaacgttgaa ccatatctag cagatatttt
    34021 ttgtctacag tcaaacactt ttcaaaatcc caaacttggt ctggtaaatg agtaagggat
    34081 ccgttgaagt taatcatagg agtgtctaag cccagttcac ggtaaaaatc ttttgacata
    34141 cggtaagggc gacctgtcgt aataataacc tgatggcctt tttcagcaac ttttttgatg
    34201 gtttttttgg taaagtcaga aatttgactg tctgagttga gcagggttcc atctaggtca
    34261 actgcaataa tttttttcgt catatggacc tttctagtgt gttttcagat aagatgtctt
    34321 ctattataac agaaagcagg cagaaaagca gattccaaac aaaaaatgaa attggattaa
    34381 tttcttaaac aaatcaaaca aagacattga aaaagtgaat gataaatgat ataattctat
    34441 tattgttcgt aaaaattaaa aggagattga tgatggacaa attatttaaa ctaaaagaga
    34501 acggtacaga cgttcgtaca gaggttctcg ctggtttaac aactttcttt gcaatgagct
    34561 atattctctt tgtaaaccca caaattcttt cgcaaacagg aatgcctgct cagggtgtgt
    34621 ttcttgcaac gattatcggt gcagttgctg gtaccttgat gatggccttc tatgctaact
    34681 tgccatacgc tcaagcacca ggtatgggac tcaatgcctt ctttaccttt acagtcgtat
    34741 ttggacttgg ttattcatgg caagaagccc tagctatggt cttcatctgt gggattattt
    34801 cattggttat taccttgaca aatgttcgta aaatgatcat tgaatcgatt ccaaatgccc
    34861 ttcgctcggc tatttcagct ggtatcggtg tcttccttgc ctatgtaggg attaagaatg
    34921 ctggactttt gaaatttacg attgatccag gcaactatac tgttgtagga gaaggggctg
    34981 acaaagctca agcaacgatt gcagcaaact cttcagcagt tccaggcttg gtcagcttta
    35041 ataatccagc tgttttagtg gctcttgcag gacttgccat tactatcttc tttgtcatca
    35101 aagggattaa agggggaatt attctctcta tcttgacaac aactgttctt gctattgcag
    35161 ttggtttggt tgatttgtct agtatcgatt ttgctaataa ccatgttggt gcagcttttg
    35221 aagatttgaa gacaatcttt ggtgcagctc ttggttcaga aggtttggga gctttggttt
    35281 cagatacagc tcgcttgcct gaaactctga tggccattct tgccttctca ttgacagata
    35341 tttttgacac aattggtacc ttgatcggta caggtgaaaa agttggtatt gtagcgacaa
    35401 atggtgaaaa tcaccaatca gccaaattgg ataaggctct ttactctgat ttgattggaa
    35461 cgacagtcgg tgccattgca ggtacttcaa acgtaacgac ttatgttgag tctgctgctg
    35521 gtatcggtgc aggtggacgt actggtttga cagccttggt tgtagctatc tgttttgcga
    35581 tttcaagctt ctttagccca cttctagcga tcgtaccaac agcggctaca gctccaatct
    35641 tgattatcgt tgggattatg atgcttggta gcttgaaaaa tatccattgg gatgatatgt
    35701 ctgaagcagt tcctgccttc ttcacatcta tctttatggg attcagctac tctatcactc
    35761 aagggattgc agttggtttc ttgacttaca ctttgactaa gcttgtcaaa ggtcaagtta
    35821 aagatgttca tgccatgatt tggattttgg atgccttgtt tatccttaac tacatcagca
    35881 tggccttata atagaatgac ccagggggat ttcccccctt ttttaataca aaggagatag
    35941 gtgatgaaag agaaaaatat gtggaaagaa ttgttgaatc gtgcaggctg gattttggtc
    36001 tttttacttg ccgtcctttt atatcaggtt cccctagtgg ttacctctat tttgacttta
    36061 aaagaagtag ccctgctaca gtcagggctg atagttactg gcctttcaat tgtggttctg
    36121 gctctattta ttatgggagc tcgtaaaacc aagttagcta gttttaattt ttcttttttt
    36181 agagctaaag atttggcacg tttgggcttg agttatttag ttattgtcgg gtcaaatata
    36241 cttggttcta tcttgttgca actgtcaaat gagacgacaa cagctaacca gtctcagatt
    36301 aacgatatgg ttcagaatag ttctctgatt tctagcttct tcttgctagc cttgcttgct
    36361 ccaatttgtg aggaaatctt gtgccgtggg attgttccta aaaagatttt ccgaggcaag
    36421 gagaacttgg gatttgtagt cggtacgatt gtgtttgctt tattgcatca accaagtaat
    36481 ttaccttctt tattgattta tggaggtatg tcgacagttc tatcttggac ggcctacaag
    36541 acccaacgtt tggaaatgtc gatcttgctt cacatgattg ttaatgggat tgctttctgt
    36601 ttgttggctc ttgtggtgat tatgagtcgg acattaggaa tttctgttta aaagttttta
    36661 tgtaggaacc gacctctttc tactagggaa agatgaatgc aatcgtgtcc atctttttct
    36721 ttttatggta aaatagaaaa ataatatgat gaaaatcctt gagggagtga ccgatatgtc
    36781 aagtaaagcc aatcatgcaa agacagttat ttgcggaatt atcaatgtaa ccccagactc
    36841 cttttcggac ggtggtcaat tttttgctct tgagcaggca ctccagcagg ctcgtaaatt
    36901 gatagcagaa ggagccagta tgctcgatat cggcggagaa tcgactcggc cgggaagtag
    36961 ctatgttgag atagaagagg aaatccagcg tgttgttcca gtgatcaaag cgattcgcaa
    37021 ggaaagtgat gtcctcatct ctattgatac ttggaagagt caagtagcag aggctgcttt
    37081 ggctactggt gccgatctag tcaatgatat cactggtctc atgggtgatg aaaaaatggc
    37141 ccatgtggtt gctaaagctg gagcgaaagt ggtcatcatg tttaacccag ttatggctcg
    37201 acctcagcat cctagttcgc ttatcttccc tcattttggc tttggtcaaa cctttacaga
    37261 aaaagagtta gctgactttg aaacattgcc aatcgaagac ttgatggtgg ctttctttga
    37321 acgagcacta gcgagagcgg cagaagctgg tattgcacca gaaaatatcc tgttggatcc
    37381 aggaattggc tttggtctga ccaagaaaga aaatcttctc cttttacggg acctggataa
    37441 actacatcag aagggctatc caatctttct cggagtgtcg cgcaagcgat ttgtcatcaa
    37501 tatccttgaa gaaagtgggt ttgaagtcaa tcctgagaca gagcttggtt tccgaaatcg
    37561 ggacacggct tcggctcatg taactagtat cgctgcgaga cagggtgtag aagtggtgcg
    37621 cgtgcatgac gtagctagtc acaggatggc agttgaaatt gcctctgcca ttcgtctggc
    37681 tgatgaagcg gaaaatttag atttaaaaca atataaataa gatgaaagaa attgaaaaca
    37741 atcagtggat tgctaactac cggacggatc aaccgcattt tggcttggaa cgaatggtgg
    37801 aactgttagc tttgcgtggc aatccccatc ttaaactcaa ggttctccat atcggaggga
    37861 ctaacggcaa gggctcgact attgcttttt tgaaaaagat gctagaaaag ctagggctga
    37921 gagttggcgt gtttagttcg ccctatctca ttcattacac agaccagatt agcatcaatg
    37981 gggaatcgat ctcagaagcg aggctagaag ctctcatggc agactatcag tctttgctgg
    38041 agggagaagc ggtcgccaat ttacagggca caaccgagtt tgagattatc acagccctag
    38101 cctatgacta ctttgcctca gagcaagtag atgtggctat catggaagtt ggcatgggtg
    38161 gacttttgga tagtaccaat gtctgtcagc ccattttgac aggaattaca actattggct
    38221 tggatcatgt ggccctactt ggtgacacct tggaggccat agcagagcag aaggcaggta
    38281 ttatcaaaca agggatgccc ttggtaacag ggcgtattgc tccagaagcc ttgactgtga
    38341 ttgaccgcat tgcggaaggg aaagatgcgc cgagacttgc ctacgggaca gattatcagg
    38401 ttcgtcatca agaaagtgtg gtgacagggg aagtctttga ctatacaagt gctgtcagac
    38461 aaggtcgctt ccagactagc ctgcttggtt tgtaccaaat agagaatgct gggatggcca
    38521 tagctttact tgatactttt tgtcaagaag atggtcgaga gctagcaagc aatgactttc
    38581 ttggtcaagc cttggaagaa acaagttggc cagggcgttt ggaaatcgtg tcaagagatc
    38641 ccttgatgat tttggatgga gcccataatc cccatgctat caaggccttg ttggtaacct
    38701 tgcaagaacg ttttgcggat tatcataagg aaatcctctt cacttgtatc aaaaccaaag
    38761 ccttggggga tatgttggac ttgctgggag ccatgccaga taccgagctt actctaacac
    38821 attttgcgga tagtcgggcg acggatgaaa gcgtgctgaa agaggcagct aagtctagaa
    38881 atctcagcta ccaagattgg catgattttc tagagcagaa tttgacagat aaaaaagaag
    38941 agaaacaaac agttaggatt gtcacaggtt ccttgtattt cttgagccaa gtgagggcct
    39001 atctgatgga gaggaagaac gagaatggat acacaaaaga ttgaagcagc tgtaaaaatg
    39061 attatcgagg ctgtaggaga gaacgctaat cgcgagggct tgcaggaaac acctgctcgt
    39121 gtagcccgta tgtatcaaga gattttttca ggtcttggtc aaacagcaga ggaacatttg
    39181 tcaaaatcct ttgaaattat tgacgataat atggtggtag aaaaggatat ctttttccat
    39241 accatgtgtg aacaccactt cttgccattt tatggtagag cgcacattgc ctacattcca
    39301 gatggtcgtg tggcaggctt gtctaagcta gcccgtacgg ttgaagttta ttcgaaaaaa
    39361 ccacaaattc aagaacgttt gaatatcgaa gtggccgatg ccttgatgga ctatctaggt
    39421 gctaaaggag cctttgttgt cattgaggcg gaacatatgt gtatgagtat gcgtggtgtt
    39481 agaaaaccag gcactgcaac cttgacgaca gtagctcgtg gtctatttga aacagataag
    39541 gacctccgcg accaagctta tcgtttaatg gggctataaa aagaatccgt ttcaagcgga
    39601 tttttctaga aaggaatcat tatggatcaa ctgcagatta aggatttgga aatgtttgcc
    39661 tatcatggtc tttttcctag tgagaaagaa ttggggcaga aatttgtcgt ttcagccatc
    39721 ctatcctatg atatgaccaa ggcagctaca gacttggatt taacagcctc tgtccattac
    39781 ggagaattgt gtcagcagtg gacgacttgg tttcaggaaa cgagtgaaga tttgattgaa
    39841 acggtagcct ataaactggt ggaacgtacc tttgagtctt atcctcttgt ccaagaaatg
    39901 aagttggaac tgaaaaaacc ttgggcaccg gtgcatttgt cactagatac ttgctcggta
    39961 accattcatc gccgcaagca acgagccttt atcgccctag gaagcaatat gggagataaa
    40021 caagcaaact tgaagcaagc cattgacaaa ctgcgagctc gtggcatcta tattctcaaa
    40081 gagtccagtg tcttagcgac ggagccttgg ggtggagtgg agcaggatag ctttgccaat
    40141 caagtggttg aggtggaaac ctggctacca gcacaagact tgttagaaac cttgttagcc
    40201 attgagtcag agctgggacg ggtgagagaa gtgcattggg gacctcgttt gattgatttg
    40261 gacttgctct ttgtggagga ccagatcctt tatacagacg acctcatatt gcctcatcct
    40321 tacatagcgg aacgcctttt tgtccttgag tccttacagg aaattgcgcc tcattttatc
    40381 catccgatat taaaacaacc gatccgtaac ttgtatgatg ctttgaaaaa atagaaaaac
    40441 tctagttttc agttacttgc aactgaaggc tagagttttt aaaataggtc attttcttct
    40501 gggaggagga tagtttctct accgtccatg tctaaaacca gtactcttgg gggataacga
    40561 gggtcgaaag gatggttaaa gtcaaaatca atggctgtag ggaggtgttg acttgaaaag
    40621 tggaaggtaa tctttccttg gttattaagc aattgaaact cgagttcttc ttccaattca
    40681 aagacatttt ttaagaaatg gtcgataata taccaaaaag agtcaatgat gtcatcaggc
    40741 aagctggtaa caatgccaaa actagcagac cgcatgtggg tattggtaaa agccatatct
    40801 ctgtctcctt tcttttccct tatcatacag caaataggat taaaaatcaa gaaaaggtga
    40861 ttttttgaaa aggattttaa ctacagggaa aaagaaggaa aaaaattccc aaaaatctac
    40921 cgaagttaat aggtaaattc ccaaattaac ttgattatat aactttcagt tattttgaga
    40981 agttaccgaa aaatattttt tatatctatt gacttttagg ggtgaaattt ggtatgatag
    41041 taggcggtat tgtttacccc atttgaaagg ccccggaacc ttccaaatac ttttcgatgg
    41101 gaaggaacac ccatcaccgt aaacaaaaat cgaactatat ataggagaaa tcatgaacaa
    41161 aacaacattt atggctaaac caggccaagt tgaacgtaaa tggtacgtag ttgacgcaac
    41221 tgatgtacca cttggacgtc tttctgcagt agttgctagc gtacttcgcg gaaaaaacaa
    41281 accaacattt acaccacaca ctgatacagg tgacttcgtg attgttatca atgctgaaaa
    41341 agttaaattg actggtaaaa aagcaactga taaaatctac tacactcact caaaccaccc
    41401 aggtggattg gaacaaatct ctgcaggtga acttcgttct aaaaatgcag tacgtttgat
    41461 tgagaaatca gttaaaggta tgcttccaca caatacactt ggacgcgctc aaggtatgaa
    41521 gttgaaagta tttgttggag ctgagcacac tcacgctgca caacaaccag aagttcttga
    41581 catttcagga cttatctaag gaaaggaaca ataaagtatg tcacaagcac aatatgcagg
    41641 tactggacgt cgtaaaaacg ctgttgcacg cgttcgcctt gttccaggaa ctggtaaaat
    41701 cactgttaac aaaaaagatg ttgaagagta catcccacac gctgaccttc gtcttgtcat
    41761 caaccaacca ttcgcagtta cttcaactgt aggttcatac gacgttttcg ttaacgttgt
    41821 aggtggtgga tacgctggtc aatcaggagc tatccgtcac ggtatcgctc gtgcccttct
    41881 tcaagtagac ccagacttcc gcgattcatt gaaacgcgca ggacttctta cacgtgactc
    41941 acgtaaagtt gaacgtaaga aaccaggtct taagaaagct cgtaaagcat cacaatttag
    42001 taaacgttaa ttcgaaagaa ttactatact tatacagagc acctttcggg gtgttctttt
    42061 tttatacttt cttactaaat tggtgcaatt gacacagttg ttgcgacttt agtcgcttac
    42121 aaatgtggct gcaacctgac aaggtcagtt gcctcaaaac gttaatcaat acaattatat
    42181 caacgtttca aagcactcaa gagtttacct catgggtgct ttttttatgt tttttgaaaa
    42241 agttcacctc aaagtttacc ttattttcac cttattgttt tagagactgt aaggcaaatt
    42301 caccgacggc catagggact acattagaag tattgacata aatctgtgtt gtacctgtgt
    42361 cgctatgtat tagagcttca gaaatggctt ctaagctcat tcctgcttgt ttagcgagcg
    42421 ttgctccggt atgacgtagt ttgtgtggcg tagcgtgtgt aagctctggg tgtcgttttc
    42481 tgatagtttt catcttatta ttgagatagt cagaatgtaa aggtttattg atattgcctt
    42541 tggtatctat gtaagtaaag atgaattgtt ctggattact gatgatacca aactttgcca
    42601 gttcatattt ttgttgtttt ttccatgaag tcagaagttg aagtaagtca ttagaaatag
    42661 agaaaatggg aaatgtttcc acaataaaac gcatattatc agatggttaa tgcgttttat
    42721 atttgggttt gaggcttata aaataggata agcgtactga aaacttagat atgacaaaca
    42781 aaataaaatt tttaaaagct acatagaaac atggtataat gtatctaaag gaggtagcat
    42841 atgtccttag atatagataa agaaaagatg acaatcatgg gaatagcttt tgaaaaccga
    42901 tccgttttta agagtgtttg gtatgcttta agtacaaata tgattgaagg atggcgacct
    42961 acggttagtg atgttgaaaa attacgagat gaagctcttg ctctggggat gacttaatga
    43021 agcgcaactg ttatgaatct tatgactatg ttgatccgga taatttatat accgatccgg
    43081 gttcttcagt tctaagaaat aagcaggaag gaaaaaagca cgcgagcttg aatatcgtat
    43141 gattgctagt aagagtttga aattatttat caatcctatc ttagttaata gtttaaaagt
    43201 agtttgtttc acaactgcat aagcttagaa aagttgaaaa gtgataactc tttaataaac
    43261 tcttggtttg ttaaaagata ttttgtccac tacatttttt tcaattgact attatttgtc
    43321 atagatataa cagatagaac attgcattca gaataatgaa aaacgcatca aaaatggtgc
    43381 gttctgtttt tatgctacca taaaaggagg aaaacaaatt gaaaattttt aagggagagt
    43441 tttatcgaat ctctgtatta acagacaagc tagtaaggtt agaatactct cgaactggaa
    43501 attttgagga tagaacgaca caacttatct ataatagaga ttttggccaa gtttcgttag
    43561 attatatcga gacatcaaat gtactagata ttatgacgga ctattttcat ctgcacttta
    43621 ataaaggaga atttaacgcc gaaaatttat ttatagaatt aaaaggaaat tttgccgtat
    43681 atggtagtcg ctggtatttt ggtgaatcta ttgaaacgtt aaaaggaaca gctcggactc
    43741 tggataaggc agatggagca atctcgttag aagatggaat tattagccga aatggtatag
    43801 ccttattgga tgattctcaa ggatttattt gggatgaaca atctggttat attgagagag
    43861 aaaatcaaat tgacctgtat ttctttgcct atgggcatga ttatagagga gcaatcagag
    43921 acttttacca tttgactggt tcaacaccct tgttgccaag atatgcttta ggcaattggt
    43981 ggagtagata ttggccttat acgtcggatg aatacttgga tttaatagac agatttgaaa
    44041 cagagaaaat tccattatct atcggtgtgt tagatatgga ttggcatata actgacattc
    44101 cagctcgttt tggaagtggc tggacaggat atagttggaa tagaaactta ataccaaatc
    44161 cagaacagtt attgcaacaa cttcatgata gaaagttaaa actctcctta aatgtccatc
    44221 ctgctgatgg gatacgggct tatgaagaag cttatcctca aatcgcaaaa cgattggggt
    44281 taaatgtaga actagaagaa cctgctattt ttgatttttt taatccctct tttagggaag
    44341 cctactttaa agatgttcat tatgagttag aaaagcaggg agtagatttt tggtggattg
    44401 actggcaaca agggacacaa ggtatgctag atccactttg gcttttaaac cattatcact
    44461 atcaggatag ttgtaaaaat gcagaaggtg gtttgatttt atcaagatat gcaggtcctg
    44521 gtagtcaccg ctaccctgtt ggtttttcag gggatactat tattagttgg aattccttaa
    44581 gatttcaacc ctattttaca gcgacagcat ctaatatcgg ttatagttgg tggagtcatg
    44641 atatcggtgg acatatgttg ggggattatg acgaagagct acaaactaga tggctacagt
    44701 ttggtgtttt tagtccgatt actcgattac atagttctag aagtcctttt aatagtaaag
    44761 aaccttggtt tttttcagaa acaacatcta agattatgaa gaaatacctc cgtttgagac
    44821 atcagatgat tccctatcta tataccatga atgtaaagac acatgaggaa ggtgccccat
    44881 taatcagtcc aatctattat ttctatccag agaatgatga gagctataat gttccaaatc
    44941 aatacttttt tggaacagaa ctgatggtgg ctcccattgt agaaaagatg gatttgacat
    45001 tccaatctgc aaaagtagat gtatggttcc ctgaaggtga atggtatgac tttttttcag
    45061 agaaaaaata cacaggtggt gtgaagttaa gtgtttatag agacatctcg actacgcctg
    45121 tgtttgcaaa aagtggtgca atcattccct tggttggttc tgagataggt atgggtgttg
    45181 atttacctga agttgtagat tggtatgtat tcccaggaaa acaacattct tttgaaatgc
    45241 ttgaagatca aaatggtcaa agatataaaa caagattatc aatcgattgg gaaatgggaa
    45301 tggtagagtt agcattacaa ggagattcta gtatcgttcc aagcaataga aaacatagaa
    45361 ttcattttaa aggaacgaat gtgtctataa ttgaattgcc aaataagaat gatacagcta
    45421 aatttgaatg gaaagataat aaaaggacat ctttaaatga cgaagttttt agactactaa
    45481 agacagcttc tcttccatat gaattaaaag atagattgtt aaatcaattc atcaatgcga
    45541 aaaactctca tgacttaatg aatatcttgc atcatcagga taaggaattg agagggcgtt
    45601 tgttggaaat gatatttact agccaaaact aattgaaata attagaaagt catttgttta
    45661 gtgtatatga agattctgta tggtattcgt tatcactggt cacattgaaa atgtgaaata
    45721 agcacctaca acatagactt tacaacactt catgttttat atcatggggt gtttttctat
    45781 ttaagtcaaa gcccatcaaa aaatctcact attcatcagg ttaaaggaaa cctaatcata
    45841 gtgagattgt gaattatagt agagtttgta tcgcctcttc aatttgtttt gggtctgttt
    45901 ttgaagaaaa gcgttcaaag acttgcccat ctcgaccgat gagaaactta gagaaattcc
    45961 attcgattcg ttttcctagt gggccggatt tctggtcttt taaccagaca tagagagggt
    46021 ctgcttcctt accgttgacc ttaatcttgg caaaacgtgg gaaggtggtt tgaaaatgta
    46081 ggctacagaa ggcgttgatt tcctctgcgc tgccgggtgc ttgtcccata aactgattgc
    46141 aagggaaatc caatatttcg aagccctgag cttgatagcg ttcatagagt tcttgaagtc
    46201 cctggtactg gggcgttaaa ccacatccag tagcagtgtt gacaatcaag agaactttgc
    46261 cacgatagct atccaaggga gttgcttggt tgttttggtt caaaacggaa aaatcataaa
    46321 gtgaagtcat gagggcctct tttctttttc tacattgtaa cagtttttac ttttttcgtc
    46381 gagtcggatg gaagatattg ttgaagaata agtcttcaat atgatagaaa ccgtttacaa
    46441 ataactttaa aaatggtatg atttaattaa accggtttac ttagttgcta taaatctcta
    46501 atttgagatt tagttcctat tgattttaca atatgtttat tggagtgtat acatgcaaac
    46561 aaaaacaaag aagctcattg tgagtttgtc ttcacttgtt ttatcaggat ttttattaaa
    46621 ccattatatg acagttggag cggaagaaac gactacgaat accattcagc aaagccagaa
    46681 ggaagttcag tatcagcaaa gggatacaaa aaatttagtt gaaaatggtg attttggtca
    46741 gacggaggac ggaagcagtc cgtggacagg aagcaaagct caggggtggt cagcttgggt
    46801 agaccagaag aatagttctg cagatgcctc aactcgagtc attgaggcta agggtggggc
    46861 tatcactatc tcaagccatg agaaattaag ggcagcggtt caccgtatgg ttcctattga
    46921 agctaagaaa aagtataaac tgcgtttcaa gattaaaaca gatcataaag tcgggattgc
    46981 caaggttcgt atcattgagg aaagtggtaa ggacaagcga ttgtggaatt ctgcaacgac
    47041 gtcaggaaca aaggactggc agaccattga agcagactat agcccgactt tagatgttga
    47101 taaaatcaag ctggagttat tctatgaaac aggaactggg actgtttcct ttaaggatat
    47161 tgagctggta gaggtagcag accagctttc tgaggattct caaacagata aacagcttga
    47221 ggaaaagatt gatttaccaa ttggaaaaaa acatgttttt tctcttgcgg actatactta
    47281 taaggtagaa aatcctgacg ttgcttcagt caaaaatgga attttagaac ctcttaagga
    47341 agggacaacc aatgtcattg tcagtaaaga tggcaaggaa gtgaaaaaga ttcctttgaa
    47401 gattctagcc tctgttaagg atgcatacac agcccgtttg gatgactgga atggcatcat
    47461 cgctgggaat caatactatg attctaaaaa tgaacagatg gccaaattaa accaggaatt
    47521 ggaaggaaag gtagctgata gcctatctag tatttcaagt caggcggacc gcacctattt
    47581 gtgggaaaaa ttttcaaatt ataaaatgtc tgcaaatctg actgccactt atcggaaatt
    47641 ggaggagatg gccaagcaag tgaccaatcc ttcttctcgt tattatcaag atgaaactgt
    47701 cgttcgaaca gtcagggatt ccatggaatg gatgcataaa catgtctaca atagtgaaaa
    47761 gagcattgtt gggaactggt gggattatga aatcggtaca cctcgtgcca tcaacaatac
    47821 cttgtctctg atgaaagaat acttctctga tgaggaaatt aaaaaatata cagatgtgat
    47881 tgaaaaattt gtaccagatc ccgaacattt ccgaaagacg actgataacc catttaaggc
    47941 tctaggtgga aacttagttg atatgggaag agtaaaagta atagctggtt tactgcgtaa
    48001 ggatgatcaa gaaatttctt ctaccattcg ctcgattgag caagtgttca agttggtaga
    48061 ccaaggtgaa ggtttttatc aagatggatc ctatatagac cataccaatg ttgcctatac
    48121 gggtgcttat gggaatgttt tgattgatgg cctgtctcaa ctgttgccag tcattcaaaa
    48181 gaccaagaat ccaatcgata aagataaaat gcaaaccatg tactactgga ttgataaatc
    48241 gtttgctcct ttgctggtga atggagagct gatggatatg agtcgtggac gctcgatcag
    48301 tcgtgcaaat agcgaggggc acgtggccgc agtagaagta ctaagaggga ttcaccgaat
    48361 agcggatatg tctgaaggag aaaccaaaca acgtttgcag agtcttgtga agaccattgt
    48421 tcaatcggat agttattatg atgtctttaa gaatttgaag acttataagg atatcagttt
    48481 gatgcaatcc ttgttaagtg atgcaggagt cgcaagtgtt ccaagaacaa gttacctatc
    48541 tgcctttaac aagatggata aaacagccat gtacaatgca gagaaagggt ttggatttgg
    48601 cttgtcactc ttttccagtc gtaccttgaa ttacgaacac atgaacaagg aaaataaacg
    48661 tggttggtat acgagtgatg ggatgttcta tctttacaat ggcgatttga gtcactatag
    48721 cgatggctac tggccaacag ttaatccata taagatgcct ggtacaacag agacggatgc
    48781 taagagagcg gatagcgata caggtaaagt tttaccgtct gctttcgttg gaacgagcaa
    48841 actagatgat gccaatgcga cagcaaccat ggatttcacc aactggaatc aaacattgac
    48901 tgctcataag agctggttta tgctaaagga taagatcgcc tttttaggaa gcaatatcca
    48961 aaacacttca acagatactg ctgcaactac aattgaccag agaaaactgg aatcaagtaa
    49021 tccatataaa gtctatgtca atgataaaga agcctccctt acagaacaag aaaaggatta
    49081 tcctgaaacc caaagtgtct ttttagaatc atccgattcg aaaaagaata ttggttactt
    49141 tttctttaag aagagttcaa tcagtatgag taaggctttg caaaagggag cctggaagga
    49201 tatcaatgaa ggacagtcag acaaggaagt tgaaaatgaa tttcttacga ttagtcaggc
    49261 tcataagcaa aatggagatt cttatggcta tatgctcatc cctaacgtgg gtcgtgccac
    49321 cttcaatcaa atgataaaag agttagaaag tagcctcatc gaaaataacg aaacccttca
    49381 gtctgtttat gatgccaaac aaggagtttg gggcattgtg aaatatgatg attctgtctc
    49441 tactatttcc aaccaattcc aagttttgaa acgtggagtc tataccattc gaaaagaagg
    49501 ggatgaatat aagattgcct actataatcc tgaaacccag gaatcagctc cagatcagga
    49561 agtctttaaa aagctagagc aagcagctca gccacaagta cagaattcaa aagaaaagga
    49621 aaaatctgaa gaggaaaaga accattcgga tcaaaagaat ctccctcaga caggagaagg
    49681 tcagtcaatc ttggcaagtc tagggttctt gctacttggg gcgttttatt tattccgtag
    49741 aggaaagaac aactaatttg ttcatcatct agatgaatta catgaaactg tggaaaatag
    49801 aaaaaatccg aagaaggcca aatatcttcg gatttttctt ttaaaaaagg ataagttgat
    49861 acttatcctt tttacttcat tatgtgacta tagcgttttg aaactagaat aggacatcat
    49921 aactgctaaa agatttctat aaattcattt gattttccta atcaatttgt tcgtatccta
    49981 tttcactcta ctatattagt ccgtctcgca cctcacggag cgagacaaaa caaccacccg
    50041 ctatgcgggt gcgcgtcgaa ggttatacca aaaaaactcc aaacgcgata caataaaggt
    50101 gttcaaccca cttgtaaagc gaaaggagaa aaaatatggc acaaaaggct catagtttat
    50161 ctcacacaaa gtggaggtgt tctatcacat tgtgttcacc cctaagtata gacgaaaagt
    50221 catctataat caatatagaa gtagtttagg cgaaatattt catcgcttgt gtagttataa
    50281 aggtgttgaa atgatcgagg gtcacttaat gccagaccat gtacacatgt tagtcagtat
    50341 tccactaagg ctaagtgttt cgagtttcat gggttattta aaaggcaaaa gtgcactcat
    50401 gatgtttgac aaacacgcca atctcaagta caagtttggg aatcggcatt tctgggcgga
    50461 aggttattat gtaagtccag tagggcttaa tgaagacaca attaagaaat atagtcaaga
    50521 ttaaagaaat tatcgagtgg atgatttctt cacgagtatg aaaatttgag aactagtaaa
    50581 gtatgatata tagtaaaatg aaataagaac aggacaaaat cgatcaggac agtcaaatcg
    50641 atttttaaca atgttttaga agtagaggtg tactattcca gtttcaatct actatagcac
    50701 tagataaatt gagtgtaaaa gaatatgagg atccctttag ggatagtggt aagtaatacc
    50761 aaagtctctt aaagaggcaa gtgacgagtc aagagcaata aggcttgaac aacgtgaaag
    50821 ccagcgtctt taggcgctgg ctgatgattt gggcttatag ctctgagata aaccacccgt
    50881 tagacgggta gttatgattt tatctgagtg taacatactg ttgggcaatc tcgctgatgc
    50941 ggtcaaagtt gccttgggaa gcgagtttat tgagttcgcc accaattcca acggcatctg
    51001 caccagcagc gaaccattga gggatgttgt ttagaccgac tcctccggtt accattacgg
    51061 aaacttgtgg aatcggtgcc ttgactgcag agatatatgc tggactgaga gtactacctg
    51121 ggaagagttt gatgatttca ctaccggctt caagtgcagt cgtgatctct gtgagggtaa
    51181 tacagcctgg aatgtacggt gtgctgtaga gattgcacat tttcgcagtt tcagcatgga
    51241 aagatggaga aacaacgtaa tttgctccgg ctagaatggc atctctagca gttacggcat
    51301 caagcacagt acctgcaccg atacaaacac tctgatcgtc ctgatacaag tctacaagtt
    51361 ccttgatgat ttgtcctgca tactgattgg tataggcgat ttcaatagct ttgataccgc
    51421 ccttgataca agcaatcgag gcttgtagtc cttcttcctt tgtatttcct cgaatgacag
    51481 caacaatttt ctgttttttt agttcaataa ttgtatctga tttggtcatg taattctcct
    51541 aacgaatgat atcttgtgca tttgccagta aattttcaat actagttgcg gaagtggaga
    51601 gatggtctcc tggaagagtg catttgagag ttgcgctcgc aactgcaaag tcaatggtag
    51661 tttttaggga ggaatgatgg agtagttggt aaagggcacc agatataaag gcatccccgc
    51721 taccaattcg ttgatagact gcagttttta gttggacaga ctcttcaaat cgttcttcca
    51781 gagcataggc ttgatagaca tttttgtctt gctcatcact agagcggagg gtatggaaaa
    51841 tggccttgaa accataggct tcttttaaaa gtcgcatgcg attttccacc tcttctaggc
    51901 tagcactgtc tcttggaaac atctctagat tttggtcatc aatcatgaga ggatcaatac
    51961 cgaagcaata gtcagtaaaa cgtgcaaact tagaaaattc atacttggct tctaggactg
    52021 aaatcatctt tgttctcaga ttgagatcca ttgaaacgac aattcctcgg cgcttggctt
    52081 cttccaagag taggagaagg atcgcacgga cctcttgacc gatagctacg gtgattccac
    52141 taaaatgaaa atggctaatc ccctgaaaga gagaatccat atctagcatg tttggccgaa
    52201 tctggctgat actcgtatgc ttacgatcgt agaaaacttc actttgacga caaccaaagc
    52261 cgttctccaa atagtagagg ccgattcgat cgccaagccg acagattgaa ctggtatcga
    52321 tttggtgctg tttcaagaat gtgagaaaac gatctccaat ctcgttggca gggagtgcgg
    52381 taaagacttt cgttgagata cccagggctt gcaaattaca agcgatgtta atttctgatc
    52441 cgccaaaata agtcgaactg gcaacatgat ctccgatact ggtggcatct aatggtgaga
    52501 ttcgaattaa tggttcgcca aacagtaata ttttcgtcat ccattagttc ctttctggtt
    52561 tagaatagct ttacttggct aatacttctt tcaaataagc agcgacttca tcatcttggc
    52621 agttttcaaa gaagtattct tggaagtatt tgccagatat ggtgtctttg aggaagtctt
    52681 ggtcgattgt tttaaggatg gtcatcaaat cattgtgggt gatttgtttc acctcgttta
    52741 agatacgagc gttgcgttgt tcagggatta cacgttctct tgggtagcca ccgcccattt
    52801 cttcagcaaa taagcgttca aacatcaatt tgagggtcag ttctgccccc cagccaaatc
    52861 ctttggcata agggatagac aaggcgttac caccattgat ttgagaataa aggtaagcgt
    52921 cagttgggtc cactgctaga ccacagacaa caccagggaa gctgtttaaa gcaagcatag
    52981 cccctacacc cgtaccacag ccggtaacaa caaagtcaac tgcctttgta tttaaaagga
    53041 tggcagccat tagtccgttc tgcacataag ttaattgact ttctccttct tctccacgca
    53101 taccatagtt aaataattgg tagtcttttt tatctgtcgc ttcttttaga ctatcgtaaa
    53161 taatgtgatt cttgctagct tgactatttt cattgattaa tgcgattttc ataagatctt
    53221 ctttctattt ttactcaggt tgttttccga tgtaggctaa gataccgcca tctacatata
    53281 ggatgtggcc attgacaaaa ttgctggcat cactagcgag aaagacagca gggcccatca
    53341 aatcttcagg atttccccaa cgtgcagcag gtgtttttgc aatgatgaac tggtcaaatg
    53401 ggtggcgaga accatcttct tgcaactcac gaagaggtgc tgtttgagga gtggcaatat
    53461 aacccggtcc aattccgtta cattggatat tggctccacc gtattcagac gcaatgttgc
    53521 gggtcaacat tttcaagccc cctttagcag cagcataagc gctaactgtt tcacgtccca
    53581 gttcgctcat catcgaacaa atattgataa tctttccatg ccctttcttt atcatagaag
    53641 gaataactgc ctttgaaacg ataaatggtg cgtttaagtc aatatcgatg accttacgga
    53701 aatcagcggc gctcatttcg cacattggaa ctcggcggat aataccagcg ttattaacga
    53761 ggatgtcaat gacaccaacc tcttgttcga tttgcttgac catggcttgg ataccgtcct
    53821 cgtctgtcac gtcacagaca tatccatggg cttcgatgcc aacttcacga taagcttcaa
    53881 tccctttatt gaccagatct tgattgatat cgttaaagac aatagtagcg ccggcttcag
    53941 cgtaggattt ggcaatagca aatccaattc cataagaagc gccggtgatg agagcaattt
    54001 ttccttttaa agaaaactgc tcaattgaga atgatgtatt tgtcatttga tacttccttt
    54061 caaatttgtt aagacttctc tataaccaaa ttatattcta gtaaaccggt tttgtcaata
    54121 aataaatatt tttatttata aaaagattta ttttccttaa aaatggaata ttttgaaatt
    54181 tctgtctatt aaaatggtta aaaagataat gaaagcgcta atattttttt aaaaaaacta
    54241 ttgacaagat aaaaataaag gattacaatg gggaatataa agtaaaccgg taaacctaaa
    54301 caagaaagga gaaaagatga aaattgtact tgtagggcat ggacattttg ctacagggat
    54361 ttatagttct ttacaattga ttgcaggcaa tcaagaaagt gtggaggcga ttgactttgt
    54421 ggaaggaatg tcagcagatg aactcaagca aaaaatctta cttgcaattt caaatgaaga
    54481 agaagtttta atcctaagtg atctcttggg aggatcgcca ttcaaggttt cttctaccat
    54541 aatgggagaa aatccagcca aaacaatgaa tgttctctcg ggtttgaact tagccatgtt
    54601 aatggaagca gtctttgcta gaatggctca tagctttgat gaggttgtta ataaatcagt
    54661 agtggcggcc cagggcggag tcgtaaatgg taaagaattg ttttcaacgg atgcagagga
    54721 agaggaagaa gatttcgaat cgggtattta aagggtaaaa gaatgataaa aaaggttacg
    54781 attgaaaaaa taaaatcgcc tgagcgcttc ttagaagtac cacttctgac gaaagaagaa
    54841 gtcggccagg caatcgataa ggttattcgg cagttagaac tcaaccttga ctatttcaag
    54901 gaagatttcc ctacgccagc tacctttgat aatgtctatc caatcatgga taacacggaa
    54961 tggaccaatg gtttctggac aggagaactg tggttggctt atgaatacag tcaacaggat
    55021 gcatttaaaa acatcgctca taaaaatgtt ctttctttcc tggatcgtgt caataagaga
    55081 gtagaattgg atcaccatga tctcggcttc ttgtacacac cgtcttgtat ggctgaatat
    55141 aagataaatg gagatggaga ggctagagaa gcaaccttga aagctgcaga taagttgatt
    55201 gaacgctatc aagaaaaagg tggttttatt caagcttggg gagacttggg caagaaagag
    55261 cattaccgtt tgattatcga ctgcttgctc aatatccaac tcttattctt tgcttatcaa
    55321 gaaacaggcg atcaaaaata ctacgatatt gcagaaagtc atttctatgc ttcagctaat
    55381 aatgtaatcc gtgatgacgc ttcgtccttc cacaccttct attttgatcc tgagacaggt
    55441 caacccttta aaggtgtaac gagacaaggg tatagtgatg attcatgctg ggcacgtggt
    55501 caatcatggg gagtctatgg tattcctttg acttatcgtc acttaaaaga cgagtcctgc
    55561 tttgacttgt ttaagggtgt gaccaattat ttcttgaatc gtctgccaaa agatcatgtg
    55621 tcctattggg atttgatttt taatgatggt agtgatcaat cacgagattc ttcagcaaca
    55681 gctatcgccg tctgtgggat tcatgaaatg ctaaaacatc tcccagaggt ggatgctgac
    55741 aaagatattt ataaacatgc tatgcatgcc atgcttcgtt ccttgatcga acattatgca
    55801 aatgatcaat ttacccctgg tgggacaagt ctcctccacg gtgtgtactc atggcattca
    55861 ggtaaaggag tggatgaagg caatatctgg ggtgactact attacctaga agcccttatc
    55921 cgtttctaca aagactggaa cctatattgg taggaggaga aatatgacaa tgccaaatat
    55981 tattatgacc cgtatcgatg aacggttgat tcatggacaa ggacaacttt gggtaaaata
    56041 cctaggttgt aatacggtca ttgttgccaa tgacgaagta agcacggaca agatgcaaca
    56101 aactctgatg aaaacagttg tgccagactc agttgccatg cgtttcttcc ctttgcaaaa
    56161 ggtgattgat atcattcaca aggctaatcc tgctcaaacg atctttatcg ttgtaaagga
    56221 tgtgaaggac gctttaacct tggtagaagg tggtgtccct atcaaagaaa tcaatattgg
    56281 gaacattcac aatgctactg gtaaagagca agtgacacgc tccatcttcc tgggtgaaga
    56341 ggacaaggca gccctcaagg aattaagcca aactcatcaa gtaacattta atacgaaaac
    56401 aactccaaca ggaaatgatg gagctgttca agtcaacatt atggactata tttaaaagag
    56461 gagatcgtta tgtcgattaa tgtatttcaa gcgattttaa ttggattatg gacagctttc
    56521 tgttttagtg gaatgctatt aggaatttac accaatagat gtattgttct gtcatttggt
    56581 gtcggaatta ttctaggtga tctgcctact gctcttgcaa tgggagctat tggtgaattg
    56641 gcttatatgg gattcggtgt tggtgctgga ggtactgttc caccaaaccc aatcggacct
    56701 ggtatctttg gtaccttgat ggctatcact agtgctggta aagtcagtcc agaagcggct
    56761 cttgccctct ctactccgat tgctgtggcg attcaattct tacaaacttt cgcctacact
    56821 gtacgtgctg gtgcgcctga aacggcgatg aagcacttga aaaaccataa tttgaagaaa
    56881 ttcaagttca ctctaaatgc aacaatttgg ttgtttgcct ttattggatt taccttgggt
    56941 tgcttgggtg ccctttcaat ggataccttg ttgaaactcg tagactacat tccaccggta
    57001 ttgcttacag gtttgacagt tgctggtaaa atgctcccag ctatcggttt tgcgatgatc
    57061 ttgtcagtga tggctaagaa agagttgatt ccctttgtct tgttgggata tgtttgtgca
    57121 gcttatctaa acatcccaac aattggtatt gcaattgtag gtactatctt tgctttgatt
    57181 gaattttata acaagccaaa aacagcggat catgtggtag aggaggaagc acacgatgac
    57241 tggatctaac aaattaacaa aacgtgatta tcttaaaacg tctttgcggg cattcttttg
    57301 tcaaaatgga tttaactata gtaactatca agggttggga tatgccaatg tgatgtatcc
    57361 tgctttgaaa aaacactatg gagagaatca ggaaggtttc taccaagcct tggaagaaaa
    57421 ctgtgaattc tataatacca acccacactt cctgcctttt attaccagct tgcatcttgt
    57481 aatgttggaa aatggccgtc cggcaaaaga aacacgtagc atcaagatgg ccttgatggg
    57541 accattagca ggtattgggg attctctctc tcaattctgt ttagctccat tgttctcaac
    57601 catcgcagct tcgtttgctc aagaaggctt ggttgtcggt ccaatcttgt tcttccttgc
    57661 gatgaatacg attttaacag cgattaaatt gtcaactggt ctgtatggat acaaactagg
    57721 aacgactgtg attgataaac taagcgagca gatggcaacg atttctcgta ttgccaatat
    57781 tattggtgta accgtaattg ctggtttggc agcgacatct gttaagatta tggtaccgat
    57841 cacctttgct gcaggggaag ttaaagcaga cgctaaacaa agtatcgtaa gtattcaggg
    57901 aatgcttgat aaggttgctc cagctcttct accagcccta tttacacttt tagtttacta
    57961 cttgatcaaa gaaaagaaat ggacaacata taaactcgtt attttaacag ttatcatcgg
    58021 aattatcgga agctggctta agattatagc ttaatggata caacattgtt ttatggaata
    58081 gtgattgtct tggcagtgag tcccctttta ctgtcaagct ttcattctat tcgtcagcaa
    58141 aagttgcttc gcaaacagat ggagcaacga caagagtatt tagcttcttt aacatctggt
    58201 gatgaagtgt tgttattgtc tggaattcat ggaaaaatca tttctatcca agatgacttg
    58261 gtctccttgc agattgcaaa aggtgtggtc atctatgtag aaaaggaaag tgtaatggga
    58321 aagacaaaag aactgctttt taagtagttc tttttctggt aatagataat gaaagaagaa
    58381 agaagacaat tttttgaaag aatcgatgga aaccaatgtc gtgattatat cttgtcccac
    58441 tgttcaaaag actatgagaa agtcaagagt tcccttgaac gcttgatgga caatcgtttt
    58501 atgtttgata gtccttggga tatggagcct tgttcaaaaa tccatcaaat ccagccgatg
    58561 gtatgggatc aagtatttga agatgatcca gaatggtctt atatgctcaa tcgacaagaa
    58621 tatctcttgc agtttatgat agggtatgtg gtagaaggag ataaggacta tattcaaaag
    58681 tgcaagttct ttctatttga ttggattgag caggtgagag aattttctcc tcaatccttg
    58741 atgactagaa ccttggatac cggtattcgt tcctttactt ggttgaaact actcttgctc
    58801 ctcttgaaat ttgacttgct agaggagaaa gaactagaga aaattttggt cagtctagaa
    58861 aagcagattg actttatgaa aagccactat cgcgccaagt acacccttag taactgggga
    58921 attttacaaa caattccgat gcttgctatc tatcatttct ttgcagataa gatggaccta
    58981 gaagaagctt accattttgc ttcagaggag ttgaaacagc aaattgagac acagatttta
    59041 ggagatggaa gccagtttga acagtcgatt ctctatcatg tagaggttta taaagccttg
    59101 ctggatttgt gtctcttgct tccagacttg caagatagtt accaagagtt gctggaaaag
    59161 atggcgacct atattcaaat gatgacaggc ttagatggac gaactttggc ttttggtgat
    59221 agcgattcta cagaaacgac agaaatgttg agcctgtctg ctgtggtttt gaacaaggaa
    59281 gaccttctta acggtctgga tgttaaagtc gatttgctta gcctcttgtt cctggggcga
    59341 gaaaaggtca agcgactgca ggaatttgaa aagcgagctt ggcagcctaa gttcatgagc
    59401 tttgaagact ctggacatgt ctgcattaag gatgaacatc gttatctatt tttcaaaaat
    59461 ggtccgctag gaagtgccca tagccatagt gacgagaata gtttttgctt acagtatcaa
    59521 ggccaaccta ttttcataga tgctgggcgt tattcttatc gggagatata tgaacgttat
    59581 ctcttaaaga gtgcttggag tcattcgacc tgcattgtag atgggaaagc tccggaaaga
    59641 atcacgggat cctgggaata tgaatactat cctcactccc tgttttgtca ccataaagaa
    59701 agggagggaa tgcattatat tgaaggggct tattggtcag cagaacctga tttgccttat
    59761 cttcacagga gaaaaatcct catgttggta gaggatgtct ggctcttggt agatgacatc
    59821 aggtgtcaag gtcagcatga ggcgttgact cagtttatcc ttgacaagga tgtgacctat
    59881 caagatggga aaatcaatca gttgagacta tggagtgaag ttgattttga tttggaagat
    59941 accatcattt ctcctaaata caatgagctt gaaagaagta gcaaactcac caagcgccaa
    60001 ttctttgaga atcagatgct ggattatacc atcattgcgc atgagagttt tgaaatcatc
    60061 cgtcattctg tctaccagac agatgatcgt gaagtggaaa atgctctggc ttttgaagtg
    60121 aaaaatgacg aaacagacaa gctgattctg ttattaagcg aggatatttg tgtaggtgaa
    60181 aaattgtgcc tcgttgacgg aacaaaaatg cgtggaaaat gtctagtata tgataaaata
    60241 aatgagagaa tgattcgctt gcagtgctag aaataggcat tttgaatagt gaatatgtta
    60301 taataagtat tagtaggagg tgttttagat tggagaagaa actgaccata aaagacattg
    60361 cggaaatggc tcagacctcg aaaacaaccg tgtcatttta cctaaacggg aaatatgaaa
    60421 aaatgtccca agagacacgt gaaaagattg aaaaagttat tcatgaaaca aattacaaac
    60481 cgagcattgt tgcgcgtagc ttaaactcca aacgaacaaa attaatcggt gttttgattg
    60541 gtgatattac caacagtttc tcaaaccaaa ttgttaaggg aattgaggac atcgccagcc
    60601 agaatggcta ccaggtaatg ataggaaata gtaattacag ccaagagagt gaggaccggt
    60661 atattgaaag catgcttctc ttgggagtag acggctttat tattcagccg acctctaatt
    60721 tccgaaaata ttctcgtatc atcgatgaga aaaagaagaa aatggtcttt tttgatagtc
    60781 agctctatga acaccggact agctgggtta aaaccaataa ctatgatgcc gtttatgaca
    60841 tgacccagtc ctgtatcgaa aaaggttatg aacattttct cttgattaca gcggatacga
    60901 gtcgtttgag tactcggatt gagcgggcaa gtggttttgt ggatgcttta acagatgcta
    60961 atatgcgtca cgccagtcta accattgaag ataagcatac gaatttggaa caaattaagg
    61021 aatttttaca aaaagaaatc gatcccgatg aaaaaactct ggtatttatc cctaactgtt
    61081 gggccctacc tctagtcttt accgttatca aagagttgaa ttataacttg ccacaagttg
    61141 ggttgattgg ttttgacaat acggagtgga cttgcttttc ttctccaagt gtttcgacgc
    61201 tggttcagcc ctcctttgag gaaggacaac aggctacaaa gattttgatt gatcagattg
    61261 aaggccgcaa tcaagaagaa aggcaacaag tcttggattg tagtgtgaat tggaaagagt
    61321 cgactttcta aaatgaagga aaatgacttg caatctctgt taagaaataa aataatccca
    61381 cctagaacaa gctaggtggg attatttgcc tatgaaatga gaaattatgg gagcaagctc
    61441 ctaaatcaac tgtttttgat ctacttcttt aactacttga taaaagttat agaagtaggc
    61501 caaacttgaa atgatggtta cgactaggaa tattgaaaat ttccattgga cagggttggt
    61561 taaaagttgt ggaaaggata tgaggagaaa gaagagggct gcgttgagga caggtatccg
    61621 ttttgattgt attttctcaa gtcctttatt gagcgcagga agaaagagga gtaggagtag
    61681 taaaactgta tgagaaacag ctcctgaaat aagggcaaag aaaaggaaaa tactgataaa
    61741 aacatgaatg atcagtagtc tagctagtga tttcataagg tacctcctaa tcctggtctt
    61801 ttttagctct tgcaatacga agtgagtcga caatatgtat catcactccg aaaaagaaag
    61861 ctcccagtat agttttaaaa atatgttttg tatttagaag agaactgata aaatttggat
    61921 tttcacttgt tagggtatca atgagtggaa ttataaaaaa tatcactgtt ccataaatcg
    61981 aacctgcttt cagaccagga taacgtaact gtttcttttc ttttttcatg agtttgctcc
    62041 ttttttaaaa atcttcctcc caaaagagac tgttgaggtc agtttggagg ctgcgggcga
    62101 gattgagaca gagttccaag gttggattgt acttgtcgtt ttcaatcata ttgatagtct
    62161 gtctcgagac accgatatcc ttggcgagtt cgagctggga aatacccaat tccttgcgaa
    62221 attctttcac acgattcatc tggtctcctt tctgatttat gtcgtatata tttgactata
    62281 ttatagtctt ttaaacataa agtgtcaagt atttttgaca tattttttga agaaatagta
    62341 gtctccttgt cctatttgtc tgacaagtgc aagctggtcg gatttgtggt aaaatagata
    62401 agatatgaca aaagaatttc atcatgtaac ggtcttactc cacgaaacga ttgatatgct
    62461 tgacgtaaag cctgaaggta tctacgttga tgcgactttg ggcggagcag gacatagcga
    62521 gtatttatta agtaaattaa gtgaaaaagg ccatctctat gcctttgacc aggatcagaa
    62581 tgccattgac aatgcgcaaa aacgcttggc accttacatt gagaagggaa tggtgacctt
    62641 tatcaaggat aacttccgtc atttacaggc acgtttgcgc gaagctggtg ttcaggaaat
    62701 tgatggaatt tgttatgact tgggagtgtc tagtcctcaa ttggaccagc gtgagcgtgg
    62761 tttttcttat aaaaaggatg cgccactgga catgcggatg aatcaggatg ctagtctgac
    62821 agcctatgaa gtggttaatc attatgacta tcatgatttg gttcgtattt tcttcaaata
    62881 cggtgaggat aaattctcta aacagattgc gcgtaagatt gagcaagcgc gtgaagtgaa
    62941 gccgattgag acaacgactg agttagcaga gattatcaag ttggtcaaac ctgccaagga
    63001 actcaagaag aagggtcatc ctgctaagca gattttccag gctattcgaa ttgaagtcaa
    63061 tgatgaactg ggagcggcag atgagtccat ccagcaggct atggatatgt tggctctgga
    63121 tggtagaatt tcagtgatta cctttcattc cttagaagac cgcttgacca agcaattgtt
    63181 caaggaagct tcaacagttg aagttccaaa aggcttgcct ttcatcccag atgatctcaa
    63241 gcccaagatg gaattggtgt cccgtaagcc aatcttgcca agtgcggaag agttagaagc
    63301 caataaccgc tcgcactcag ccaagttgcg cgtggtcaga aaaattcaca agtaagaggg
    63361 aaaaagatgg cagaaaaaat ggaaaaaaca ggtcaaatac tacagatgca acttaaacgg
    63421 ttttcgcgtg tggaaaaagc tttttacttt tccattgctg taaccactct tattgtagcc
    63481 attagtatta tttttatgca gaccaagctc ttgcaagtgc agaatgattt gacaaaaatc
    63541 aatgcgcaga tagaggaaaa gaaaaccgaa ttggacgatg ccaagcaaga ggtcaatgaa
    63601 ctattacgtg cagaacgttt gaaagaaatt gccaattcac acgatttgca attaaacaat
    63661 gaaaatatta gaatagcgga gtaagatatg aagtggacaa aaagagtaat ccgttatgcg
    63721 accaaaaatc ggaaatcgcc ggctgaaaac agacgcagag ttggaaaaag tctgagttta
    63781 ttatctgtct ttgtttttgc cattttttta gtcaattttg cggtcattat tgggacaggc
    63841 actcgctttg gaacagattt agcgaaggaa gctaagaagg ttcatcaaac cacccgtaca
    63901 gttcctgcca aacgtgggac tatttatgac cgaaatggag tcccgattgc tgaggatgca
    63961 acctcttata atgtctatgc ggtcattgat gagaactata agtcagcaac gggtaagatt
    64021 ctttacgtag aaaaaacaca atttaacaag gttgcagagg tctttcataa gtatctggac
    64081 atggaagaat cctatgtaag agagcaactc tcgcaaccta atctcaagca agtttccttt
    64141 ggagcaaagg gaaatgggat tacctatgcc aatatgatgt ctatcaaaaa agaattggaa
    64201 gctgcagagg tcaaggggat tgattttaca accagtccca atcgtagtta cccaaacgga
    64261 caatttgctt ctagttttat cggcctagct cagctccatg aaaatgaaga tggaagcaag
    64321 agcttgctgg gaacctctgg aatggagagt tccttgaaca gtattcttgc agggacagac
    64381 ggcattatta cctatgaaaa ggatcgtctg ggtaatattg tacccggaac agaacaagtt
    64441 tcccaacgaa cgatggacgg taaggatgtt tatacaacca tttccagccc cctccagtcc
    64501 tttatggaaa cccagatgga tgcttttcaa gagaaggtaa aaggaaagta catgacagcg
    64561 actttggtca gtgctaaaac aggggaaatt ctggcaacaa cgcaacgacc gacctttgat
    64621 gcagatacaa aagaaggcat tacagaggac tttgtttggc gtgatatcct ttaccaaagt
    64681 aactatgagc caggttccac tatgaaagtg atgatgttgg ctgctgctat tgataataat
    64741 acctttccag gaggagaagt ctttaatagt agtgaattaa aaatagcgga tgcgacaatt
    64801 cgagattggg atgttaatga tggtttgacg actggtggga tgatgacttt cttacaaggt
    64861 ttcgctcact ccagtaatgt tggaatgagt ctacttgaac aaaaaatggg agatgctact
    64921 tggttggatt atctaaaccg ctttaagttt ggggttccga cgcgttttgg tctgactgat
    64981 gagtattcag gtcaattgcc tgcagataat attgttaata ttgccatgag tgcatttggt
    65041 caggggattt ctgtaacgca gacccagatg ctacgtgctt ttacagccat tgccaatgat
    65101 ggggttatgt tggagcctaa atttattacg gccttgtatg atccaaatga tcaaaccgtt
    65161 cgtaaatctc aaaaagaaat cgtaggaaat cccgtttcga aagatgcagc tagccaaact
    65221 cgtactcaca tggtcttggt aggaacggat cctagatatg gaactatgta caatcatagt
    65281 acaggaaagg caactgtcaa tgttccgggt cagaatgtgg cccttaaatc agggactgcg
    65341 cagattgcgg atgagaaaaa tggtgggtat cttacaggtt caacaaacta cattttctca
    65401 gttgtggcta tgaaccctgc tgaaaatcct gattttatct tgtatgtaac ggtacagcaa
    65461 cctgaacatt attcaggtat ccagttggga gaatttgcca ccccaatctt ggagcgggct
    65521 tcagctatga aagaatctct caatcttcaa tctccagcca agaatttaga taaagttacg
    65581 acagaatctt cttatgcaat gcctagcatc aaggatattt cacctggtga gttggcggaa
    65641 gccttacgcc gaaatattgt gcaaccaatc gttgtaggta ctggaacaaa gattaaagag
    65701 acttctgtag aagaagggac caatcttgca ccaaaccaac aagttctcct tttatcggat
    65761 aaggtagaag aaattccaga catgtatggc tggaaaaaag agactgctga aacctttgct
    65821 aaatggttgg atattgagct ggaatttgaa gggtcaggtt ccgtcgttca gaagcaagat
    65881 gttcggacta atacagctat caaaaacatt aaaaaaatta aattaacttt aggagactaa
    65941 tatgtttatt tctatcagtg ctggaattgt gacattttta ctaactttgg taggaattcc
    66001 agcctttatc caattttata gaaaggcgca aattacaggc cagcagatgc atgaggatgt
    66061 taaacagcac caggcaaaag ctgggactcc tacaatggga ggtttggttt tcttaattgc
    66121 ttctgtttta gttgctttct ttttcgccct atttagtaat caactcagca ataatgttgg
    66181 tatgatttta tttatcttgg ttctttatgg tttaatcgga tttttagatg acttcctcaa
    66241 ggtcttccgt aaaatcaatg agggtcttaa tcccaaacag aaattggctc ttcagcttct
    66301 aggtggcgtt attttctacc ttttctatga gcgcggtggc gatatgctgt ctgtctttgg
    66361 ttatcaagtg catctaggga ttttctatat tgtcttcgct cttttctggc tagtcggttt
    66421 ttcaaacgca gtaaacttga cagacggtat tgacggcctg gctagtattt ccgttgtgat
    66481 tagtttgtct gcctatggag ttattgccta tgtgcaaggt cagatggata tccttctagt
    66541 gattttggcc atgattggtg gtttgcttgg tttctttgtc tttaactata agcctgctaa
    66601 ggtctttatg ggagatgtgg gaagtttgtc tctcggtgga atgctggcag ctatttcaat
    66661 ggctctccac caagaatgga ctctcttgat tatcggaatt atttatgtct ttgaaacaac
    66721 ttcggtcatg atgcaagtcg gctatttcaa aatgactggt ggtaaacgta ttttccgtat
    66781 gacgcctgtg catcaccatt ttgagcttgg aggattgtct ggtaaaggaa atccttggag
    66841 cgagtggaag gttgatttct tcttttgggg agtggagctt ctagcaagtc tcctgaccct
    66901 agcaattttg tatttgagat aagaatggca ccctgatgtt tcagggtgtt tttgcttttt
    66961 aaaaaatatt ggtcaattaa agtcaaacct cttgaccttt tttgactaat gtagtatatt
    67021 atgaacgtaa ggtaaatgaa agccttacta gaacacttat ttaaagtaaa atagaaagag
    67081 gtggggtcta tgtttaatct agaaatcttt agaagtaaag atagtctact cctgcttgaa
    67141 aaagaaaaac cagaaatagt acctagagta gcgatttagc tagtctaaat tttttaaaga
    67201 aaaagtcaaa gatagtcaat gtcagtaata ataaataata aaaagaggta aagaatatga
    67261 ataataactt taataatttt aacaacatgg atgatttatt taaccaattg atgggtggta
    67321 tgcgaggata tagttctgaa aatcgtcgct acttgattaa tggacgtgaa gtgacacctg
    67381 aggaatttgc tcactatcgt gcaaccggtc aattaccagg aaatgcagaa gttgatggcc
    67441 aaatgcaaca acaggcatca ggtatgaaac aagacggtgt ccttgctaaa ctgggtcgaa
    67501 atttgacagc agaagcgcgt gagggcaaac tggatccagt catcggacga aacaaggaaa
    67561 ttcaagagac atctgaaatc ctctcacgcc gtaccaagaa caatcctgtt ctagtcggag
    67621 atgcaggtgt tggtaagacc gcagttgtcg aaggtctagc acaagcgatt gtgaatgggg
    67681 atgttccagc tgctattaag aataaggaaa ttatttccat tgatatttca ggtcttgagg
    67741 ctggtactca ataccgtggt agctttgaag aaaacgttca aaacctagtc aatgaagtaa
    67801 aagaagcagg caatattatc ctcttctttg atgaaattca ccaaatcctc ggtgctggat
    67861 ctactggagg tgacagtggt tctaaagggc ttgcggacat tctcaagcca gctctctctc
    67921 gtggtgaatt gaccgttatt ggagcgacaa ctcaagacga ataccgtaac accatcttga
    67981 agaatgctgc tcttgctcgt cgtttcaacg aagtcaaggt caacgctcct tccgcagaag
    68041 atacttttaa aattcttcaa ggaattcgtg acctttatca acaacaccac aatgtcatct
    68101 tgccagatga agtcttgaaa gcagcggtgg attattctgt ccaatacatt cctcaacgta
    68161 gcttgccaga taaggctatt gaccttgttg atgtaacggc agctcacttg gcggctcaac
    68221 atcctgtaac agatgtgcat gctgttgaac gtgaaatcga ggcagaaaaa gacaagcaag
    68281 aaaaagcagt tgaagcagaa gattttgaag cagctctaaa ctataaaaca cgcattgcag
    68341 aattggaaaa gaaaattgaa aaccacacag aagatatgaa agtgactgca agtgtcaacg
    68401 atgtggctga atctgtagaa cgaatgacgg gtatcccagt atcgcaaatg ggagcatcag
    68461 acatcgaacg attgaaagat atggctcatc gcttgcaaga caaggtgatt ggccaagaca
    68521 aggcgattga agctgtagct cgtgctatcc gacgtaaccg tgctggtttt gatgaaggta
    68581 atcgcccaat cggtagcttc ctctttgtag gtccaactgg ggttggtaag acggagcttg
    68641 ctaagcaatt ggcactcgat atgtttggaa ccaaggatgc gatcatccgt ttggatatgt
    68701 ctgaatacag tgaccgcaca gccgtttcta agctaatcgg tacaacagct ggttatgtgg
    68761 gttatgatga caatagcaat accttaacag aacgtgttcg tcgcaatcca tactctatca
    68821 ttctcttgga tgaaattgaa aaggctgacc ctcaagtcat tacccttctc ctccaagttc
    68881 tagatgatgg tcgtttgaca gatggtcaag gaaatacagt aaacttcaag aacactgtca
    68941 ttattgcgac ctcaaatgct ggatttggct atgaagccaa cttgacagaa gatgcggaca
    69001 agccagaatt gatggaccgt ttgaaaccat tcttccgtcc agaattcctc aaccgcttta
    69061 acgcagtcat tgagttctca cacttgacta aggaagatct ttctaagatt gtagacttga
    69121 tgttgtttga agttaaccaa accttggcta agaaagacat tgatttggta gtcagtcaag
    69181 cggctaaaga ctatatcaca gaagaaggtt acgatgaagt catgggtgtt cgtccactcc
    69241 gtcgcgtggt tgaacaagaa attcgtgata aggtgacaga cttccacttg gatcatttag
    69301 atgctaaaca tctggaagca gatatggaag atggcgtttt ggttattcgt gagaaagcct
    69361 aagacagaat tttgagaata aaaaagaagg agccagctga aaaaaactgg ttccttttga
    69421 ggtacgacgg gcatgtcgtg tagtagagat gtactattct agtttcaatc tactatagta
    69481 gctcagaaat cggtacttaa acgtgctata tcaaaaccag tccttgaaaa acgtggactg
    69541 gtttcgtgtt tggattatta ctttgaacga catgcgttaa aagttagttg aaccgccgta
    69601 tgccgaacgg tacgtacggt ggtgtgagag gggctagaga ttatccccta ctcgatttta
    69661 aatcacatga cgttcaaagg catcatctga aatcccttgt tccaagatga gttttgccca
    69721 ttctttagca gagaagaggc tgtggtcctt gtagtttccg caagattcga tggttgtccc
    69781 tgggacatct tcccaagtag tagtttcagc gatttccttg agcgaatcct tgataacagc
    69841 tgcgatttta gcactggtgt gacgtcccca cataatcatg tggaagcctg tgcggcaacc
    69901 aaatggcgaa cagtcaatca tgccgtcaat gcgggtacgg atgagtttgg ctaagaggtg
    69961 ctcgatagtg tgaaggccgg cggtagggat agagtcttcg tttggttgca ccaagcgaat
    70021 atcataattg gagatgatgt ctccttttgg tcctgtttct tccccaatca agcgaacata
    70081 gggtgctttg acaatggtgt ggtcaagttc aaaactttcg acaataactt cttttgacat
    70141 ggtaaatcct ttcagttttc ttctctcatt atatcataaa ggttgctcct gagacagaga
    70201 gaaaacctct ccgaggctgg agaggttgaa atctttactt acgatataag cggtcgtatt
    70261 ggtagtatgg gtcaaaggtt acgttgatac ccagtttacg aaggacattc ttgtcttcat
    70321 cagtcaagat gatggttgag tgggcttcgc ttcctttgag gttgccgagt tcttccatag
    70381 cgcgggtagc atcaggattt tctgtagctg tgatagcaag tgcaatcagg atttcatttg
    70441 aatgaaggcg tggattgcgg ctaccgagat gatcgatttt aagaccttgg attggcttaa
    70501 caacttccgg ctcgattaat tttacttctt tagcgatgtc agctgatttt ttgatggcgt
    70561 tgatcaaggc agcggctgta gggccaaaga gttctgagtt cttaccagtg acgatttccc
    70621 catttggcaa ttcaaaggct agggctggtc caccagtttc ttctgctttt tggcgcgcaa
    70681 cgacagcaac cttacggtct gcaggtgtga taccgaggtc gttcatgagc aactcaattt
    70741 tcttgacggc agcttcgcca actttttcag ctttgaagtc aagaactgtt tgatagtaac
    70801 ggcggatgat ttcttgttta gaagcttcga cagcggcctc gtcatctgta atagcgaaac
    70861 caaccatgtt gacacccata tctgtcggtg aagcgtatgg tgattttccg agaatacgtt
    70921 ccaacatgcg tttgagcact gggaagattt cgatatcacg gttgtagttg acagtggttt
    70981 ctccataggt ttggagatgg aaggggtcaa tcatgttgac atcatcaagg tcagctgtgg
    71041 cagcttcata agccaagtta actggatgat gaaggggaag attccaaaca gggaaggttt
    71101 caaatttagc gtagccagat ttgatgccat tgatttggtc gtggtacata ttggacatac
    71161 acgttgccaa ttttccagaa ccaggtccag gagcggttac gacaatcaag ttgcgactgg
    71221 ttttgatgta gtcgtttttg cccatgcctt ctggggaaat gatgtgatcc atatccgtcg
    71281 gatatccttt gattggataa tgaagatatg aatcaattcc gtttttctca agttggttgc
    71341 ggaaggcatc tgcagcgggt tggccagcgt attgtgtaat gacaacggaa ccaacaaaaa
    71401 tccccaattc attgaatttg tcaatcaaac gaagaacttc ttggtcataa gaaatgccta
    71461 agtcgccacg tgctttggaa tgttcaatgt tgctagcatt aatggcaatc acaacctcaa
    71521 cctgctcttt caattcttgc aagagcttga ttttgttgtc aggttcataa ccaggaagga
    71581 cacgagcagc gtggaaatct tctaacattt taccgccaaa ctctaagtag agcttgccgt
    71641 caaattggtt aatacgctcc aaaatatggt cgcgttgtaa attcaaatat tgttcagaac
    71701 taaaagcttg ttttttcatt tttttacctc tggactctat tataataaaa aattggaagt
    71761 taggaaacta cggagctaaa aaagaaatta aaaagattaa gcaaacgctt gcacaaaatt
    71821 ttaaaaagtg ctatcataga ctatagatta ttaaaataat gaggtaaaca gatgcaagaa
    71881 aaatggtggc ataatgccgt agtctatcaa gtctatccaa agagttttat ggatagtaat
    71941 ggagatggag ttggtgattt gccaggtatt accagtaagt tggactatct agccaagcta
    72001 ggaatcacag caatttggct ttctcccgtt tatgacagcc ctatggatga taatggttac
    72061 gatattgctg attatcaagc gattgcaacg atttttggaa ccatggagga tatggatcaa
    72121 ctgattgcag aagctaagaa gcgtgatatc cgtatcatca tggacttggt ggtcaatcat
    72181 acctcggatg agcatgcctg gtttgtagag gcctgtgaaa atcctaatag ccctgagcga
    72241 gactactata tctggcgcga tgaacccaat gacctagatt ctatctttag tgggtctgct
    72301 tgggaatacg atgaaaagtc aggtcaatac tatctccact ttttcagcaa gaaacagccg
    72361 gatctcaact gggaaaatga aaaacttcgc cagaaaattt atgagatgat gaacttctgg
    72421 attgataaag gtattggtgg tttccgtatg gatgttattg acatgattgg caaaattcct
    72481 gacgagaagg tagtcaataa tggtcctatg ctccatccct atctcaagga aatgaatcag
    72541 gcgacctttg gagataagga tctcttgaca gtaggggaga cttggggagc aacgccagag
    72601 attgccaagc tctactctga tccaaagggg caagaattgt ctatggtctt ccagtttgaa
    72661 catatcggtc ttcagtatca ggaaggtcag cctaaatggc actatcaaaa agagctgaat
    72721 atcgctaagt taaaagaaat cttcaacaaa tggcagacag agttaggagt tgaggacggc
    72781 tggaattccc tcttctggaa caaccatgac ctccctcgta ttgtctcaat atggggaaat
    72841 gaccaagaat accgcgaaaa atctgccaaa gcctttgcaa tcttgcttca tcttatgaga
    72901 ggaactcctt atatctacca aggtgaggag attgggatga ccaactatcc gtttgaaaca
    72961 ctagatcaag tagaagatat tgaatctctc aactatgcgc gtgaggctct tgaaaaaggt
    73021 gttccgattg aagaaatcat ggacagtatc cgtgttattg gacgtgacaa tgcccgtacc
    73081 cctatgcaat gggacgagag caaaaacgct ggtttctcaa caggtcaacc ttggttggcg
    73141 gttaatccaa attacgagat gatcaacgtc caagaagcgc tggcaaatcc agattctatt
    73201 ttctatacct atcagaaact ggtccaaatt cgcaaggaga atagctggct agttcgagct
    73261 gactttgaat tgcttgatac ggctgataag gtctttgctt atatacgtaa ggatggcgac
    73321 cgtcgcttcc tagttgtggc taacttgtcc aatgaagagc aagacttgac agtagaagga
    73381 aaagtcaaat ctgtcttgat tgaaaacacc ctagctcaag aagtctttga aaaacaaatc
    73441 ttagttccat gggatgcttt ctgtgtggaa atgactgact agaatgagca aacctcaagt
    73501 ttttgaagct tgaggttttt tactatagtg gattgaaact agaatagtgc acctctgctt
    73561 ctaaaacatt gttagaaatc gatttgactg tcccgatcga tttgtcctat tcttatttca
    73621 ttttgctata cttgtagttg aggagaatta agctcctcac tagtaaactc ttcataatcc
    73681 tttttatttt tatgaagata ttgtttgaaa gatgtgagtt tccacggatg ggtttgtgga
    73741 gggatatact tgcgtctttc tttttttgtt ctggttcttg ttcaaagttt ttcgaataga
    73801 gttcatgatt tagtagctcc tttgtgtgat agattttgtc agcgatattg aggtagatgt
    73861 ctccgtcaaa tgcttttata actaatgctt tcgtctttct gatgaaatag acttcttttc
    73921 cttgttcggt agggatatag taacgatttt ggaatcggat atggtgtcca ctatcgacga
    73981 ctctctccgc cagtctagcc agaatgagat tcctttcaga ggggttagga acctcctcga
    74041 agacagagag ttttgtcttg tttccaaact gttcattaaa ggtttgaatg taggaaagca
    74101 ggaaggtatt ggcttcttcc aaggtatgaa tattgttttg ttccagttcg ataggcaggc
    74161 gagattgtag tgtctgattg agtctttcga ctctcccttt agcttgaggg atagaggttg
    74221 tctcaaggag aatccctagt tggtgacagg cgtatccaaa ctgtgtatgg gtatcgtcct
    74281 ccattttctt agagttggag gcttgatagg taaagaccgt tctcttatct gttttaattt
    74341 gaaggggaat gccgtgattg gctaagattt gttcgaggac atgatagtaa gcattcaagt
    74401 tctcttgttt atcaaaataa gcgcctagga tattgccaga agcatcatca atggctaagt
    74461 gtaagttaga tgtttgggct ccaaactagg catgagggct ggcatccatt tgaatgagtt
    74521 caccagcaaa tttctttctg ggtctactag gatgtacttt tttagggtct tcaaggaagt
    74581 tttcagccgt cggtaagatt ggattgtcta ggggttgatt caggttcagt ttagcttgtt
    74641 ttcttactct cttctttgtc tttctatggg acttaggcga caggatattt ttcttataga
    74701 gtatttttct aacagtagta tcagagagct gaattccttc ttcttcagct agcaattcac
    74761 agaaatgaag gacatttggt ttatatgttt cataggagag gtattttttt aggagacgtt
    74821 ctttgatttc atcagggatt gcatgttttg gttttcgatt tctgtttccg tgtctgaagg
    74881 cttcttttcc tttcagttga taggctagta gcagacgatt gatttgtctt tcagaaagat
    74941 tgagctcgac acaggctcgt ttctttgttt tctttccttg ggctatagct tttatcacaa
    75001 gatatttttt cgtttcattc atattcagtt ggatcctttt catatgacta ttctaccaaa
    75061 tgggacattt tcacgttcga tttactaaag acattatcac attcgaatta cacaagatgc
    75121 agatagtgaa aataaaggtg tagacattac cgtaaaaaag tgatataatt gtatgatgtt
    75181 caatgtatag gtgttaatca tgagtagacg ttttaaaaaa tcaggttcac agaaagtgaa
    75241 gcgaagtgtt aatatcgttt tgctgactat ttatttattg ttagtttgtt ttttattgtt
    75301 cttaatcttt aagtacaata tccttgcttt tagatatctt aatctagtgg taactgcgtt
    75361 agtcctacta gttgccttag tagggctact cttgattatc tataaaaaag ctgaaaagtt
    75421 tactattttt ctgttggtgt tctctatcct tgtcagctct gtgtcgcttt ttgcagtaca
    75481 gcagtttgtt ggactgacca atcgtttaaa tgcgacttcg aattactcag aatattcaat
    75541 cagtgtcgct gttttagcag atagtgagat cgaaaatgtt acgcaactga cgagtgtgac
    75601 agcaccgact gggactgata atgaaaatat tcaaaaacta ctagctgata tcaagtcaag
    75661 tcagaatacc gatttgacgg tcaaccagag ttcgtcttac ttggcagctt acaagagttt
    75721 gattgcaggg gagactaagg ccattgtcct aaatagtgtc tttgaaaata tcatcgagtc
    75781 agagtatcca gactacgcat cgaagataaa aaagatttat accaagggat tcactaaaaa
    75841 agtagaagct cctaagacgt ctaagaatca gtctttcaat atctatgtta gtggaattga
    75901 cacctatggt cctattagtt cggtgtcgcg atcagatgtc aatatcctga tgactgtcaa
    75961 tcgagatacc aagaaaatcc tcttgaccac aacgccacgt gatgcctatg taccaatcgc
    76021 agatggtgga aataatcaaa aagataaatt aacccatgcg ggcatttatg gagttgattc
    76081 gtccattcat accctagaga acctttatgg tgtagatatt aattattatg ttcgtttgaa
    76141 ttttacctca tttttgaaat tgattgactt attgggaggg gtagatgttc ataatgatca
    76201 agagttttca gctctacata ggaagttcct tttcccagta gggaatgtcc atctagactc
    76261 tgagcaggct ctaggttttg tacgtgaacg ctactcacta gccgatggag accgtgaccg
    76321 tggtcgcaac caacaaaagg tgattgtggc tattcttcaa aaattaacgt caaccgaagc
    76381 actgaaaaat tatagtacga tcattaatag cttgcaagat tctatccaaa caaatatgcc
    76441 acttgagact atgataaatt tggtcaatgc tcagttagaa agtggtggaa cttacaaagt
    76501 gaattctcaa gatttaaaag ggacagatcg gatggatctt ccttcttatg caatgcctga
    76561 cagtaacctc tatgtgatgg aaatagatga tagtagttta gctgtagtta aagcagctat
    76621 acaggatgtg atggagggta gatgaaatga tagacatcca ttcgcatatc gtttttgatg
    76681 tagatgacgg tcccaagtca atagaggaaa gcaaggcact tttaagagaa gcttataatc
    76741 aaggagttcg aatgattgtg tctacttcgc atcgtcgaaa agggatgttt gaaactccgg
    76801 aagagaagat agcagaaaac tttcttcagg ttcgggaaat tgcaaaagaa gtagcagatg
    76861 atttagtcat agcttatggc gcagagatat actatactct ggatgctcta gaaaagctag
    76921 aaaaaaaaga aattcctacc cttaatgata gtcgttatgc tttgattgag tttagcatgc
    76981 atacttccta tcgtgagatt catgcgggat tgagcaatat tttgatgttg ggaatcacgc
    77041 cagtaattgc tcatattgaa cgttatgatg ccttagagaa taacgaaaaa cgtgttcgtg
    77101 aactgattga tatggggtgc tatactcaga taaatagtta tcatgtttta aaacctaagt
    77161 tctttggtga aaaatataaa ttcatgaaaa agagagctcg gtattttttg gaacgtgatt
    77221 tagttcatgt agttgcaagt gacatgcaca atttagacag tagacctcca tatatgcaac
    77281 aggcatatga tatcattgct aagaaatatg gagcgaaaaa agcgaaagaa ttttttgtag
    77341 ataatcccag aaaaattata atggatcaat taatttagga gaaaatatga aggaacaaaa
    77401 cactttggaa atcgatgtat tgcaactatt cagggcttta tggaaaagaa agttggtcat
    77461 tttattagtg gcaattataa cttcttcagt tgcttttgcc tacagtactt ttgttatcaa
    77521 acctgagttt actagtacga ctcggattta tgtagttaac cgtaatcagg aagagaagtc
    77581 tggtttaacc aatcaagact tgcaggcagg atcatacttg gttaaagact atcgtgaaat
    77641 tatcctatcg caggatgttt tggaggaagt tatttctgat ttgaaactag atttgacgcc
    77701 aaaaggtttg gctaataaaa ttaaagtaac agtaccagtt gatacccgta ttgtctctgt
    77761 ctcagttaat gatcgagttc ctgaagaggc aagccgtatc gctaactctt tgagagaagt
    77821 agctgctcaa aaaattatca gtattactcg tgtttctgat gtgacaacac tggaggaggc
    77881 aagaccggcg atatcaccat cttcgccaaa tattaaacgc aatacactaa ttggtttttt
    77941 ggcagggggg attggaacta gtgttatagt tcttcttctt gaacttttgg acactcatgt
    78001 gaaacgtccg gaagatatcg aagatacact gcagatgaca cttttgggag ttgtaccaaa
    78061 cttgagtaag ttgaaatagg agagaggaat gccgacatta gaaatagcac aaaaaaaact
    78121 ggagttcatt aagaaggcag aagaatatta caatgccttg tgtacaaata tacagttgag
    78181 cggagataaa ctaaaagtaa tttccgttac ttctgttaac cctggggaag gaaaaacaac
    78241 tacttccgta aatatagcaa ggtcgtttgc gcgtacaggc tataaaactc ttttgatcga
    78301 tggcgatact cgaaattcag ttatatcagg agtttttaaa tcgcgtgaaa aaattacagg
    78361 gctaacagaa tttttatctg ggacagctga tttatctcac ggtttatgtg atacaaatat
    78421 tgaaaattta tttgtaattc aatcgggatc tgtatcacca aaccctacag ccttgttaca
    78481 aagtaaaaat tttaatgata tgattgaaac attgcgtaaa tattttgatt atatcattgt
    78541 tgatacagca cctattggaa ttgttattga tgcggcaatt atcactcaaa agtgtgatgc
    78601 gtccatcttg gtaacagcaa taggtgaggt gaataaacgt gatgtccaaa aagcgaaaca
    78661 acaattagaa caaacagaga aactgttcct aggagttgtt ttaaataaat tggatatctc
    78721 ggttgataag tatggagttt acggttccta tggaaattat ggtaaaaaat aacttaggaa
    78781 agattttatg gatgaaaaag gattgaaaat ttttctagca gtaatacaga gtattattgt
    78841 cattttattg gtttattttc ttagctttgt tagagagaca gaacttgaac gttcttcgat
    78901 ggttatacta taccttctcc acttttttgt attctatttt agttcctatg gtaacaattt
    78961 ttttaaaaga gggtacctag ttgagtttaa tagtactata agatatattt ttttctttgc
    79021 aatagctata agtgtattaa acttttttat agcggaacgg tttagtatct ctagaagagg
    79081 aatggtatac ttcttaactt tagaaggaat atccttatac ttgttaaatt tcttagtaaa
    79141 gaaatattgg aagcatgtgt tttttaatct aaaaaatagc aagaaaattt tactgttaac
    79201 agtaacgaaa aatatggaaa aagttcttga taaattgcta gaatctgatg aactttcatg
    79261 gaaattggta gcagtaagtg ttttggataa atctgatttt caacatgata aaatacctgt
    79321 aattgaaaag gaaaaaatta ttgaatttgc aacgcatgaa gttgtggatg aggtgtttgt
    79381 caatcttcca ggagagagct acgatattgg agaaattatc tctaggtttg agacaatggg
    79441 gatagatgta actgtaaatc ttaaagcatt tgataagaat ttgggtcgca ataaacaaat
    79501 tcatgagatg gtaggattga atgtagtcac tttctctaca aatttttata aaactagtca
    79561 tgtgatttca aagagaattc tcgatatttg tggtgccact attggcctta ttctttttgc
    79621 tatagctagt ctagttttag ttccattgat tcgtaaagat ggcggatcag ctatttttgc
    79681 tcaaactcgt atagggaaaa atggtcgaca ttttaccttt tataaattcc gttcgatgcg
    79741 aatcgatgct gaagctatca aagaacagtt gatggatcaa aatacgatgc aaggtggtat
    79801 gtttaagata gacaatgatc ctcgtgttac aaaaattggt cgctttattc gtaaaactag
    79861 tttagatgaa ttgccgcagt tttggaatgt ctttatagga gatatgagtt tggtgggaac
    79921 acgtccacct acagtagacg agtatgatca gtatactcca gaacagaaac gtcgactcag
    79981 ctttaaacct ggtattacag gtttatggca ggttagcggc cgtagtaaaa taaccgattt
    80041 tgacgatgtt gtaaaattag atgtggctta tattgataat tggacaatct ggaaagatat
    80101 tgaaattttg cttaaaactg ttaaagttgt atttatgaga gatggagcga agtaattcat
    80161 atgaatgaga gaatgcaaat attaggagtt actatagatc cattaacgat gaaagaaaca
    80221 gtggatgctg ttgaacagta tgttttaaag aagcatcctt tgcacttgat gggagttaac
    80281 gcagataaaa ttaatcagtg ccatgaagat gagaaaatca aaaaaatcgt taatgaatca
    80341 ggaatcatta atgcggatgg agcatcagtt gttcttgcaa gtaagttttt aggaacgcct
    80401 gttcctgaac gagtagcggg tattgatttg atgcaatgtc ttttagagtt gtcaaataaa
    80461 aaaggatatt cagtttactt ttttggagct aaagaagaaa ttttacaaga tatgctaaaa
    80521 gtttttaaac aaagatatcc taatcttaat gttgttggct atagaaacgg atatttttca
    80581 cctgaagatg aaaaaaagat tcaggaagat attaaaggag gaaaaccaga ttttgtattt
    80641 gtagggatta cttctcctaa aaaggagtat atcatccaat cattcatgga taatgggatt
    80701 aatgctgtct ttatgggtgt tggtggcagt tttgatgtat tatcaggaca cattaaacga
    80761 gctccattat ggatgcaaaa attgaatctg gaatggttgt tccgtgtagt taatgaaccc
    80821 aaacgccttt ttaagcgtta ttttataggg aatgttactt ttattaagcg agttttagat
    80881 gaaaagcgaa aatcaaaaaa ataatattct acatatttct cgtacaatgg atattggtgg
    80941 tgcagaacgt attgtatatc aattgagttc tgatttgaaa gatgaatttg atagtgtcca
    81001 tgtcgcttca acaggtggac tatgggagag caaactttta tcaaaaggag ttcaacatca
    81061 taaaatttta gatgttgaca gtaagaatcc cctaactatg gtaaagatcc tttcaagttt
    81121 ttatagaatt atcaaaaata atgatattac cattgttcac actcatcatc ggatggctgc
    81181 cttttatatt cgcttgttga aaatcattaa tcctaagttg atacatgttt acactgcaca
    81241 taatgtattt aaaaataaat taccattata caaattttcc ttaaaaaaag cgtattgtgt
    81301 agctgtaagt aaagcggtta atgataattt gaaacatgat gtaggaatca gtgatagtac
    81361 agtaatctat aatggggttg tttttgaaaa aactgataag ctagttggtg aaattgtaaa
    81421 ctataacgga atcaaattgg ggtgtattgc taggttatca gagcaaaaag gattgaccta
    81481 cctaattgat gcgatgtctt tagtgaaaca caggaatatt acgttgttca ttgtcggaga
    81541 tggagagctt cgagatgagc ttgaaaacaa ggtgaaacaa ttaaatcttc aaaaatcagt
    81601 gatattttta ggttatcgaa aagatattgt tgaatgtatc aatagttttg attacttagt
    81661 gtcatcatct ttatatgagg ggtttggtct aaatgcaatt gaagcattta tgaaggggaa
    81721 aacgatggtt tcatcagata tcccaggaat aaatgaagta gtcaataaca aaaatgggat
    81781 tcttgttcct gttaaggatg atgttgcctt agcgagagcg attgaaaagc ttgcgactga
    81841 caaaaaactt agagaaaaac tcgcttatca agcaaaaaaa gattatgaga caaaatttaa
    81901 ttattccttg tttttggata attatcggag actttataga aaattaatgg gagaatcaaa
    81961 atgaaaaaag tcatgttggt ttttgggaca cgtccagaag ctattaaaat gtgtccttta
    82021 gtaaatgaac tgaaacaaaa tgattcaatc aagacacttg tgtgtgtaac tggtcaacat
    82081 aaggaaatgt tagagcaggt tttagaggtg ttcaaggttg tcccagatta tgatttgggt
    82141 atcatgaaag caaatcagac cctatttacc attacgacta gtatcttgga taaaattcag
    82201 gcggttctag agaaagaaaa accagatctt gttcttgttc atggagatac tacaacaaca
    82261 tttgcgacag ctttagcagc attttatatg ggaatcaaag tgggacacgt cgaagcaggt
    82321 ctcagaacct ataatctcca aagtccattt ccagaggaat tcaatcgcca gacaacttct
    82381 atcattgccg actatcattt tgcgccgact gaagttgcga aggaaaatct actaagagag
    82441 gacagaaaaa atatctttgt gacgggaaat acagtcattg atgctttgaa gacgactgtt
    82501 caagataact accatcaccc aattttagaa tgggcaaagg gtagtaagtt aatcatgcta
    82561 acggctcatc gacgagaaaa tcttgggaaa ccgatggaaa acatgtttaa tgctgttaat
    82621 cgaattttaa acgaattcga agatgtaaaa gttgtatatc ccatccataa aaatcctaag
    82681 gttcgagaat tagcaagtaa agtttttggc gataatgaac gaatgaaaat cattgaaccg
    82741 ttagaggtta ttgattttca taattttatg aatcaaagct atatgatttt gacagattct
    82801 ggaggtgtac aggaagaagc accttcttta ggaaaacctg tcttggtgat gcgtgataca
    82861 acagagcgtc ctgagggggt cgttgctggc acgttgaagt tggtaggaac agaagaagag
    82921 aatatctata gcaacttcaa acttcttctt gaagatgaaa cagaatataa caagatgagc
    82981 aaagctagca acccttatgg agatggaatg acttgtaaac ggattgttga tattattctg
    83041 gaagtataaa aataattcaa ttatggatga ggaaagaata aattagattg atgataaaaa
    83101 gaaaaatata ta
//
LOCUS       DAVKBK010000003        70262 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVKBK010000003 DAVKBK010000000
VERSION     DAVKBK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.003"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..1858)
                     /locus_tag="VWX69_000159"
     CDS             complement(<1..1858)
                     /locus_tag="VWX69_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEU9191572.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGISSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRAPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAADH"
     gene            complement(1891..4500)
                     /locus_tag="VWX69_000160"
     CDS             complement(1891..4500)
                     /locus_tag="VWX69_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU9191573.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKSMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            complement(4679..4816)
                     /locus_tag="VWX69_000161"
     CDS             complement(4679..4816)
                     /locus_tag="VWX69_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU9191574.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            complement(5018..5605)
                     /locus_tag="VWX69_000162"
     CDS             complement(5018..5605)
                     /locus_tag="VWX69_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9191575.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            complement(5698..5841)
                     /locus_tag="VWX69_000163"
     CDS             complement(5698..5841)
                     /locus_tag="VWX69_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191576.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            complement(5854..6234)
                     /locus_tag="VWX69_000164"
     CDS             complement(5854..6234)
                     /locus_tag="VWX69_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU9191577.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(6227..6567)
                     /locus_tag="VWX69_000165"
                     /pseudo
     CDS             complement(6227..6567)
                     /locus_tag="VWX69_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6581..6829)
                     /locus_tag="VWX69_000166"
                     /pseudo
     CDS             complement(6581..6829)
                     /locus_tag="VWX69_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(6829..6999)
                     /locus_tag="VWX69_000167"
     CDS             complement(6829..6999)
                     /locus_tag="VWX69_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191578.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            complement(7186..7554)
                     /gene="rplL"
                     /locus_tag="VWX69_000168"
     CDS             complement(7186..7554)
                     /gene="rplL"
                     /locus_tag="VWX69_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU9191579.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(7630..8130)
                     /locus_tag="VWX69_000169"
     CDS             complement(7630..8130)
                     /locus_tag="VWX69_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU9191580.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(8169..8304)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(8380..9639)
                     /locus_tag="VWX69_000170"
     CDS             complement(8380..9639)
                     /locus_tag="VWX69_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU9191581.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(9986..11734)
                     /locus_tag="VWX69_000171"
     CDS             complement(9986..11734)
                     /locus_tag="VWX69_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191582.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDTFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(11736..13460)
                     /locus_tag="VWX69_000172"
     CDS             complement(11736..13460)
                     /locus_tag="VWX69_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191583.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPIDKGSIDL
                     YRDGSSPRNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(13518..14456)
                     /gene="msrB"
                     /locus_tag="VWX69_000173"
     CDS             complement(13518..14456)
                     /gene="msrB"
                     /locus_tag="VWX69_000173"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9191584.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(14646..14720)
                     /locus_tag="VWX69_000174"
                     /pseudo
     CDS             complement(14646..14720)
                     /locus_tag="VWX69_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(14796..15665)
                     /locus_tag="VWX69_000175"
     CDS             complement(14796..15665)
                     /locus_tag="VWX69_000175"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU9191585.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(15667..16953)
                     /locus_tag="VWX69_000176"
     CDS             complement(15667..16953)
                     /locus_tag="VWX69_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU9191586.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQEFGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(17104..17841)
                     /gene="mecA"
                     /locus_tag="VWX69_000177"
     CDS             complement(17104..17841)
                     /gene="mecA"
                     /locus_tag="VWX69_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU9191587.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(18041..19075)
                     /locus_tag="VWX69_000178"
     CDS             complement(18041..19075)
                     /locus_tag="VWX69_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9191588.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(19103..20536)
                     /locus_tag="VWX69_000179"
     CDS             complement(19103..20536)
                     /locus_tag="VWX69_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU9191589.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(20552..21538)
                     /locus_tag="VWX69_000180"
     CDS             complement(20552..21538)
                     /locus_tag="VWX69_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9191590.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(21540..22643)
                     /locus_tag="VWX69_000181"
     CDS             complement(21540..22643)
                     /locus_tag="VWX69_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9191591.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(22633..23478)
                     /locus_tag="VWX69_000182"
     CDS             complement(22633..23478)
                     /locus_tag="VWX69_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9191592.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(23757..25031)
                     /gene="psr"
                     /locus_tag="VWX69_000183"
     CDS             complement(23757..25031)
                     /gene="psr"
                     /locus_tag="VWX69_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU9191593.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(25028..25876)
                     /gene="pheA"
                     /locus_tag="VWX69_000184"
     CDS             complement(25028..25876)
                     /gene="pheA"
                     /locus_tag="VWX69_000184"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9191594.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(25873..26349)
                     /locus_tag="VWX69_000185"
     CDS             complement(25873..26349)
                     /locus_tag="VWX69_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU9191595.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(26342..27625)
                     /gene="aroA"
                     /locus_tag="VWX69_000186"
     CDS             complement(26342..27625)
                     /gene="aroA"
                     /locus_tag="VWX69_000186"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU9191596.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(27717..28055)
                     /locus_tag="VWX69_000187"
     CDS             complement(27717..28055)
                     /locus_tag="VWX69_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU9191597.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(28066..29169)
                     /locus_tag="VWX69_000188"
     CDS             complement(28066..29169)
                     /locus_tag="VWX69_000188"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU9191598.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(29179..30345)
                     /gene="aroC"
                     /locus_tag="VWX69_000189"
     CDS             complement(29179..30345)
                     /gene="aroC"
                     /locus_tag="VWX69_000189"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU9191599.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(30355..31422)
                     /locus_tag="VWX69_000190"
     CDS             complement(30355..31422)
                     /locus_tag="VWX69_000190"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU9191600.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTELNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKTRGNTLKLVLVS
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(31441..32295)
                     /locus_tag="VWX69_000191"
     CDS             complement(31441..32295)
                     /locus_tag="VWX69_000191"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU9191601.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALENVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(32285..32962)
                     /locus_tag="VWX69_000192"
     CDS             complement(32285..32962)
                     /locus_tag="VWX69_000192"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU9191602.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(32959..34122)
                     /locus_tag="VWX69_000193"
     CDS             complement(32959..34122)
                     /locus_tag="VWX69_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU9191603.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(34807..36441)
                     /locus_tag="VWX69_000194"
     CDS             complement(34807..36441)
                     /locus_tag="VWX69_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191604.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(36422..37171)
                     /locus_tag="VWX69_000195"
     CDS             complement(36422..37171)
                     /locus_tag="VWX69_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191605.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            37350..38804
                     /locus_tag="VWX69_000196"
     CDS             37350..38804
                     /locus_tag="VWX69_000196"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU9191606.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(38894..41512)
                     /gene="alaS"
                     /locus_tag="VWX69_000197"
     CDS             complement(38894..41512)
                     /gene="alaS"
                     /locus_tag="VWX69_000197"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU9191607.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPCITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(41534..42019)
                     /locus_tag="VWX69_000198"
     CDS             complement(41534..42019)
                     /locus_tag="VWX69_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU9191608.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(42294..42533)
                     /locus_tag="VWX69_000199"
     CDS             complement(42294..42533)
                     /locus_tag="VWX69_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191609.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(42794..43864)
                     /locus_tag="VWX69_000200"
     CDS             complement(42794..43864)
                     /locus_tag="VWX69_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9191610.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(43861..44634)
                     /locus_tag="VWX69_000201"
     CDS             complement(43861..44634)
                     /locus_tag="VWX69_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191611.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(44631..45437)
                     /locus_tag="VWX69_000202"
     CDS             complement(44631..45437)
                     /locus_tag="VWX69_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191612.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(45418..46575)
                     /locus_tag="VWX69_000203"
     CDS             complement(45418..46575)
                     /locus_tag="VWX69_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191613.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(46735..47640)
                     /gene="murB"
                     /locus_tag="VWX69_000204"
     CDS             complement(46735..47640)
                     /gene="murB"
                     /locus_tag="VWX69_000204"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU9191614.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(47752..48504)
                     /locus_tag="VWX69_000205"
     CDS             complement(47752..48504)
                     /locus_tag="VWX69_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU9191615.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(48514..49245)
                     /gene="budA"
                     /locus_tag="VWX69_000206"
     CDS             complement(48514..49245)
                     /gene="budA"
                     /locus_tag="VWX69_000206"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU9191616.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            49387..50658
                     /locus_tag="VWX69_000207"
     CDS             49387..50658
                     /locus_tag="VWX69_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU9191617.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLKELERHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(50678..51493)
                     /locus_tag="VWX69_000208"
     CDS             complement(50678..51493)
                     /locus_tag="VWX69_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9191618.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(51650..52303)
                     /gene="phoU"
                     /locus_tag="VWX69_000209"
     CDS             complement(51650..52303)
                     /gene="phoU"
                     /locus_tag="VWX69_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9191619.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(52315..53073)
                     /gene="pstB"
                     /locus_tag="VWX69_000210"
     CDS             complement(52315..53073)
                     /gene="pstB"
                     /locus_tag="VWX69_000210"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9191620.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(53086..53889)
                     /gene="pstB"
                     /locus_tag="VWX69_000211"
     CDS             complement(53086..53889)
                     /gene="pstB"
                     /locus_tag="VWX69_000211"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9191621.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(53900..54784)
                     /gene="pstA"
                     /locus_tag="VWX69_000212"
     CDS             complement(53900..54784)
                     /gene="pstA"
                     /locus_tag="VWX69_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9191622.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(54774..55691)
                     /gene="pstC"
                     /locus_tag="VWX69_000213"
     CDS             complement(54774..55691)
                     /gene="pstC"
                     /locus_tag="VWX69_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9191623.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(55691..56569)
                     /gene="pstS"
                     /locus_tag="VWX69_000214"
     CDS             complement(55691..56569)
                     /gene="pstS"
                     /locus_tag="VWX69_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU9191624.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(57143..58447)
                     /locus_tag="VWX69_000215"
     CDS             complement(57143..58447)
                     /locus_tag="VWX69_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU9191625.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(58448..59221)
                     /locus_tag="VWX69_000216"
     CDS             complement(58448..59221)
                     /locus_tag="VWX69_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU9191626.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(59211..59489)
                     /locus_tag="VWX69_000217"
     CDS             complement(59211..59489)
                     /locus_tag="VWX69_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU9191627.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(59489..59890)
                     /locus_tag="VWX69_000218"
     CDS             complement(59489..59890)
                     /locus_tag="VWX69_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU9191628.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(60100..60717)
                     /locus_tag="VWX69_000219"
     CDS             complement(60100..60717)
                     /locus_tag="VWX69_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU9191629.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(60707..61480)
                     /locus_tag="VWX69_000220"
     CDS             complement(60707..61480)
                     /locus_tag="VWX69_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU9191630.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(61491..62228)
                     /locus_tag="VWX69_000221"
     CDS             complement(61491..62228)
                     /locus_tag="VWX69_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU9191631.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(62233..63363)
                     /locus_tag="VWX69_000222"
     CDS             complement(62233..63363)
                     /locus_tag="VWX69_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU9191632.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(63447..63836)
                     /locus_tag="VWX69_000223"
     CDS             complement(63447..63836)
                     /locus_tag="VWX69_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU9191633.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(63852..64235)
                     /locus_tag="VWX69_000224"
     CDS             complement(63852..64235)
                     /locus_tag="VWX69_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU9191634.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(64236..65024)
                     /locus_tag="VWX69_000225"
     CDS             complement(64236..65024)
                     /locus_tag="VWX69_000225"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU9191635.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEK"
     gene            complement(65017..65952)
                     /locus_tag="VWX69_000226"
     CDS             complement(65017..65952)
                     /locus_tag="VWX69_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU9191636.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(66082..66258)
                     /locus_tag="VWX69_000227"
     CDS             complement(66082..66258)
                     /locus_tag="VWX69_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU9191637.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(66398..67105)
                     /locus_tag="VWX69_000228"
     CDS             complement(66398..67105)
                     /locus_tag="VWX69_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU9191638.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            67256..68284
                     /gene="queA"
                     /locus_tag="VWX69_000229"
     CDS             67256..68284
                     /gene="queA"
                     /locus_tag="VWX69_000229"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU9191639.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFY
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(68945..69334)
                     /locus_tag="VWX69_000230"
     CDS             complement(68945..69334)
                     /locus_tag="VWX69_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9191640.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(69388..70080)
                     /locus_tag="VWX69_000231"
     CDS             complement(69388..70080)
                     /locus_tag="VWX69_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9191641.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVFVPFATKYEADNDLSAGQEQEITLGKNGKIVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEISIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
BASE COUNT        20986 a        15799 c        12805 g        20672 t
ORIGIN      
        1 catgatcagc tgctttgttt aaatacaaca aacttttaac tccaatagaa tttaatttct
       61 ttgaccactc tatcacttcg ttattattaa tatatgggtc tttctcaccc aaaatattaa
      121 ctataacagt atttgagtct cgtgcctttt caatattttg cataggcgaa tatgacttta
      181 tataagcctt tacttcaggg gctctaatat ctccccactc tgctatttcg gtcttagaaa
      241 gaggatcatt tggattctga agtgtatcat aaggatttat aaatggcgaa aataagagaa
      301 tgctttgcaa taaatttttt tcctcgttca acaccgcacc agcaattatt ccacctgcac
      361 tagaagttat taaacctaat cgcttactgt caattacatc attttccctt aaataattta
      421 ctccctcaat aaaatctctg atagaattcc atttgtttaa cgcctttcct gagcgatacc
      481 attcaccacc caaatagcct ccacctctta catgaactat agcataaata aaacctgcat
      541 ctattataga taacataatt tcatctaaat cagaattatc attcttacca taagccccat
      601 agacacttag aatacatttt tttcttcttg ggagctcatc cgtatcttca cttttccaaa
      661 ataaagaaat cggtatgctt acatcataac tgtctttttt agtccaaatc accttagaaa
      721 aatatttagt attattcgat tttatgatgg gtctttcaaa ttcagttttt aatgtatttt
      781 ctattaaatc aaaactaagt attttttcgt aaaaagttct cctctctaaa aacagaagaa
      841 cacgatcaga aaatgaattt tcataaagtg ttgtcttttc atcaaatgtt atcttattaa
      901 cactcaactc cctcaaacta ttatttttaa atgtagcaag ataaaagacg gaattcgctg
      961 cgtttgaaca gtctaaaagg atataacgtc ctatacagtg aactcttcta gccctatctt
     1021 gatatggtat agtaatagaa actctgtctc ccgaagaagt ttcccttaga attagttgat
     1081 ctttcttttc ttcagttgaa gagatcccaa gaaagtactg tgctttttct gtactaaata
     1141 gagcgatatc tctaggtgtt ggggctaccg tttctgtgta agagtgtcta acaaaacccg
     1201 tccggtcgaa actgtataga aaaatcctgc ctttctgaaa gtctactgac tttacaaaac
     1261 aattattgct atcaatgtgg actattttta atcgaaaaga gcattcgttt tcttcaaaca
     1321 gttcctcttc tgtaaagcta tcaaaagatt tatagaataa cttacttggc ctcccgtact
     1381 ctttggagcg agtatacata acaccgaatt tacccaaata gaacgaactt tctactgaaa
     1441 tatcttcaat gataaataac tcttccatag tatatttttt tattccaatt aaattagtgc
     1501 tacgcagtga ggatacaacc aaaactatat aactctcatc agatgaaatc ctaacatcct
     1561 gtaagatact atcatctggc aaagtatatt tttccacatc aaagacaatt ttaagtgaat
     1621 ttgaattgtc taaactggaa gaactaacct taggaatcca gtcattatct tcgacatacc
     1681 attcctttat tacaccagta ttgggtatac tccaattatc aaattggtac caatatcgcc
     1741 ctctcctaaa tatcaaagaa ttccattttt ttaattcctg aaatgatgaa gagatagacc
     1801 tcttatagtg tgttttttcc tgtattgtat ttaaaaatat ttcattactc tgattcacaa
     1861 gtatgacccc ttaataatgg tatctaaata ttatatttga ggaagaatcg tcaatttatt
     1921 atccattatt gataccaatc caattgcaac acccgcaaat cccgaagcaa tatctgttgt
     1981 tatctttaaa ccattatctc ccgcaataac aaatccttct tcaattacac acaaatatct
     2041 ataaagttgt tcaattaatt tcttttgtcc tgaaaagtta tcatcgatat cactatatat
     2101 attattagca acttcaagac cacaaaatcc gttaaataaa cctggtaata cacaaaaaac
     2161 tacatcagtt gccctctcta aagaagttaa atattttaag tatttgcttg acaagatttc
     2221 tttatttcta ttaataagta aaagcaggcc agcacttcca gttgctagat atggtagtaa
     2281 tctatgacct tggctgtact gcaatgaatt attactatct actttataag caactaattc
     2341 tttatctaca gccaattcta gaccattttt atagatactt tcaccagtta atttataagc
     2401 ttcaccgaag agccaagcta cccctgcgtg accatatagt aatccaccaa aattctcata
     2461 aggatcatta ctctgaacat cactagcgcc aactttacaa aaagtttctg gattttctat
     2521 ataatttaaa gtatattctc taagcctaat tagtatttct tctcctagtt tattatcaat
     2581 ttccccttta ctaagaaaat acagtccaac cagtaaaatt ccagcctgtc cactatataa
     2641 atttttattt tgtgaattct caaatatctc tataaaatga gttgtaaaaa gttcaactgc
     2701 ccgatctatc tccccaaatt cataaatgag ccagattgta ccaattttac catcaaaaag
     2761 accagaaagg gacgatttct taaaattatt tactgcctca ttaataacct gtgttcgaat
     2821 ctcataatag tcatcaaact tgaaattttt tactttctta gctagttgtt gataactcca
     2881 aaggatagct aaatctgaaa acgcaattcc ttgattaaaa ttcagaccat aataatgaac
     2941 tgggaagaat cttgattgaa attctttacg ccactgtcca taagttagcg taaaccctct
     3001 caataatttt ataataaaat cttgtatatc ttgctcactc tcgatagttc taatctcatg
     3061 catggatttt aaaacttttt tcctggaaat attctcaatc tgtggacatt tagaatctag
     3121 atatgacaat aaactttcta cataatctat atgttctctt gtataaccca aagactcaaa
     3181 tagttttttt ccttctatcc tggtttgact tacatagttg tatgtcaaat ccgatgtagt
     3241 tactagtggc atgtataaat aatgagctat ttgtctaata ccataccaat ctatctcact
     3301 gggaagtgtt tctcgccatg ctctaaaacc aggggctgca actttatgta caactttttc
     3361 atcatttgaa aagacagcct gttcccagtc tattatacta atctcatctt catccttaac
     3421 caagatattt cctaaatgta aatcttgatg atatacattt tcagaatgaa acttattcgt
     3481 taaatcgatg agtttttcta ctatctttga aactctcaat agataatctt tggtcttatc
     3541 aacaacttca tataaaggaa aattattggt aacccatcta tttagtggaa cgcccttcat
     3601 atgttcaatt cctaagaagg tgtgctccca gatcttaccg tgccagtata ttttaggcgt
     3661 ctcactccat tcatttagaa tttttagtgc tttgcactcc gaagctaatt tctctgaaga
     3721 ataagtacca tcaaatccta gacctgtata cggtctagcc tcttttaaaa ttattttttt
     3781 cccatcttct tttagcctag cattatatat cccaccactg tttgaaaatc taattgcatt
     3841 atctataata aagggaaagt ctccctgttt tttatctttc ttgtcaagcc atttattcaa
     3901 aaagtcaggg ggcactatac cttttggaat tttaaatact ggtaaacgtt catctttaac
     3961 aacttcatcg ccaacaatta attcatcaat agcaaccttc ttttcatcat cccttgacgg
     4021 cctaaacaca ccatacctca gatatattgg tgcttcatcc caacgtttat cgcttaaaat
     4081 atatggccca ttatattgct ttaaggcact ttctaacctt tgcaaaaccg actctaattc
     4141 attttgattt ggataacatg taataaattt accagaaaat cctcgactaa ccaatttccc
     4201 gtttcgcatg ataaatttgt cttctgtact aagatgttta aatggaattc gcatttcatg
     4261 gcaaattttt gctacatctt gtaacaattc atgtgaactg ttatactctg aactaatgtg
     4321 tattttccac ccttgtcttt caacaaattt tccaataggg tattgataaa cccactcatc
     4381 attattcatt acttcgtgcc aattaaaagg cagacttact tggtacttta tgctagtatc
     4441 tgtactataa tcattattag tgaaaaagaa aggatgctcc aaattgaaat tataatccat
     4501 aacaaaatct ccaagaaatt ttatcaaact taatatatct atagctagac agacttattt
     4561 aaataaaaag ggagaatcct ttggattctc cccatataag cactaacatt ccaacgtgca
     4621 catattggaa cgacatccat aactccagag aatctctaaa gtttacaatt taaatgaatt
     4681 aacaattttc ccaactaaaa gcactccagt taccgcaacg atttgtactg aatgtactaa
     4741 atcgcattcc atcaacttca tctgtttcgt caacttgaac agatactaat tgaagattta
     4801 atacttcttc tgccatagct agctcctcct atttaaattt ttgggattaa gtactttatc
     4861 caccctcatt atactctctc caccagtaaa atgcaagcaa ttatacaatg ttgtcacata
     4921 gaaaataatg tttccgtaac ttttcaaagt aacttccatc tctctcccaa aactggaagt
     4981 tagttttaga agttacctaa aaatcaggtc acctatttta aaaaagcagc aaactataaa
     5041 ctagtaggtt ccacaccaaa tgtagtccca tactgcccca taagtcagat ttatagcgca
     5101 ccatacctaa aaacatccca agtgaaacat acaaacacca agctagaatg gttcctgtat
     5161 gatgtgctaa ggcaaataaa acacttgtca aagcaactct gatatctaat tttctgacca
     5221 aattccataa aatttctcga tacagaaatt cttcaaccat actcgcattg attaagaaca
     5281 ataaaaatga aaaccaagga atttgatgtt gaaggccaat taagtttgct tgattcgtgc
     5341 ttccttgagc atgaatcaga ctaaaacata gacttataat cagtaggcta acaaattcaa
     5401 caccaagcca tttcatccta gatttcatat tgaccttatg cgcttgtttg cgttggccat
     5461 acatccataa aaaagaaatg agtgacgaac catagagaat ctgtagtata gttaactcac
     5521 cgatacaaag aaatttcaat aagtatagag ataccaatag gacatttact tgttggaata
     5581 tataaactgg aattattctt ttcatagtta cctccgaaat aaatcttcat aatctaaatc
     5641 taatacctgc acaatccttt ctacccatgg actttgaggc attcattgtt ccatcttcta
     5701 gtggcgaatc ttttgataca aacgattcaa ttcacttgga tagtgaaact ctcccgcaaa
     5761 catttttctg gttaactcaa tccagctgat atttctttca gccaaaataa tggacaagtt
     5821 ctcccaaaat cgttcagcca tattgcttct cctttagtta gataaataat gtgtttgcgc
     5881 catgtaaatc aattgtttcg tatctcttgg caatagagct ctagcctctt ccaaattcag
     5941 acttggataa actcgcttat ttgaaaccgc aagaggaagt ctgatggtta gttcaggatt
     6001 ttttaaaatt atctcaacga aatccgttaa tcttagattg tcacggttct taaatcgtaa
     6061 taaattggga gataaaaact caaaacaatc tgaagaatag ctcatcatct caattaattt
     6121 gtcctttgtc atttcagaaa ctgaatgaca agatacctct atgccatagt tttggaagaa
     6181 atctaaaaga agttgatttc tttgtctatt tttacttaga tagagatcaa tcatgggaga
     6241 cctcccaaag attcggttcc atttgatatt ctgacacgat taaggaatct aataaattaa
     6301 ggaatctaat aaatttgcga agttaatcgg tttcttgtct tcatcataag cttttacagt
     6361 tacttgggtt gtaagtattc cctcttttcc ctcggctcga tagccttgtc catataaaac
     6421 aaaaacgaga ttttgatgat catctacaaa ggcatcaacc ccattcttta tgtcttgact
     6481 ttcaaggaat tccataacgt tttgaagata ggattcgtaa aatagtgggt agttatgttt
     6541 tttatggtaa tcatctaaaa atgtcacttc aaactcacat ggagagtaat tttgactttg
     6601 aacagcctaa aagtgccatc aaatttgaat tggaataaat caaataaata gccccatcct
     6661 catcaatcca acctttgctc aaagacaact ccaaccgatc ttttaaaact gagtaaacca
     6721 ccttaacctc cagtttcata ttcttatacc gttcactctc aaataaaagt ttggggagct
     6781 tataataacg ctctgatgtc tgatattgat tagcggtaat acgcttcatt attgtccctc
     6841 caagactaaa attccaacat ttccaaattc atcaaatcgg attaaaccta cttgttccat
     6901 ttcatcaact aactgagttg cttttacaat atcaactccc atgatagtca tgagatgact
     6961 cttcacgaat tgacgtgatg actgtccttc cttttgcata attacctccg aaacacaaaa
     7021 aaaggggtag acaatctagt gtctaccccc gaaagtttat taaaacaaaa atcctgccaa
     7081 agaatttttg gcaggaaacc aaatcaattt atcagtttct atcaatcgct tatcgctctc
     7141 aaagactggt aaatagggat tccgcaatca aattgcgata ctctattatt taagagtaac
     7201 tgaagctcca gcttcttcca atttagcttt gatttcttca gcttctgcag ttgcaacgcc
     7261 ttctttaaca agtgctggtg caccgtcaac aagttcttta gcttctttaa gaccaagacc
     7321 agtgatttca cgtacaactt tgataacgcc aacttttttg tcgcctgcag atgtcaattc
     7381 aacgtcgaat gaatctttag cagcaccagc atcagctgca tcagctgcag caacagctac
     7441 aggagcagct gcagttacac caaattcttc ttcgatagct tttacaaggt cgttcaattc
     7501 aaggattgaa gcttctttaa tttcagcaat aatgttttca atgttcaatg ccattgttat
     7561 ttcctccaaa taagttttaa attttataat agtttttttc gtagctaggc tacgctatgt
     7621 agcttaagat taagccgcgt cttctttgct ttctgcaacc gctttgactg caagagcaac
     7681 gttgcgcact ggcgcttgaa gtacagaaag gagcatagaa agaagtcctt cgcggtttgg
     7741 aagagttgca agtgcaagaa tctcttcttt agatgcgaca gcgccttcga ttgcaccacc
     7801 tttaatttca agtgcttcag cgtttttaga aaagtcgttc aagattttcg ctggtgcgat
     7861 aacatcttca ttagaaaatg ctactgcaga tggtccaaca aatacagatg caagatcttc
     7921 aagaccagct ttttcagctg cacgacgcaa gattgagttt ttaataactt tatactcaac
     7981 ttcgcttcca cgaagctcac gacgaagaac tgtatcttgc tcaactgtca aaccacgagc
     8041 gtctacaacg acgatagatg cagcagcttt cattttttca gctactacgt caactagttc
     8101 cgctttttta gcaataattg cttcactcat tagtgtgttc acctccgtaa ttattttgct
     8161 tggggaattt ttcaaaaaga aaaacgcgcc caaacctaga cacgaaagta caatacgctt
     8221 ctttttacat gatacgtttt gtcctcggta ggatatttat gagtcgatct cccctactgt
     8281 cttaggcagt ttttttaaac cgtatataag tatagcatag tcaaaaaaag aatgcaagat
     8341 ttttgcaaac tttttttaaa atttttcgtg atttttcttt taaagttcta ctgtcaggac
     8401 ttgaccttgc ttaacaacct gttctccggc gatataaaca tcatctacat cactagattt
     8461 aactgcataa accaggtgag acagcatatt ttcctgaggt tggagatgaa ttttcccttg
     8521 tggttgaatg accagaaaat ctgcttgctt gccgacttcc agacttccta tctgattttc
     8581 cattccaagg accttagccc cttcgattgt cagtaccttg agagctgttt cgattggaaa
     8641 ctggctggca tccccacttt tcatcttctg aagaagagct gcagtccttc cttcctcaaa
     8701 catatctaga ttgttattgg aagcaaccga gtcagtcgca attccgactg ctactcccgc
     8761 tttttggagc tggataattg gagcaattcc tgatgccagt ttgaggttac tgataggatt
     8821 gtgggcgata gccacttgag aagatgccaa gcgttcaatt tctctctcgt ttaattcgac
     8881 cccgtgagca aatacggacg gatgatctaa ataacccagt tcttcaagaa aagcaagggg
     8941 gcgtttgccg tatcgtttga ggataattcc tgactcctcc ttggtctccg ccacatggac
     9001 atggagcgga atatttagct cttttgccat ttccaaactc gcttccagca agtctctact
     9061 gcagctatac ggagaatgag gtgctaccat aaccttgaaa tttggatttt tatattttaa
     9121 gatttcgtct atgatggatc gagttctgct tatagtctca gcagttgttt ctgtctctga
     9181 agaaaagaga gtcggagaaa aataacaacg catcttggaa gttttcacca cctgataaat
     9241 ttgctggata tccacaccat tgggattata catatcgtta aaggttgttg ttcctgactg
     9301 gagcatctct gtcagggctt ctttgaccgc attggtagtc atgtcgggag taaactcaga
     9361 ttctgctggc cagatatagt cattgagcca ttcatggaga ttgctgtcat ctcggatccc
     9421 tctcagacct gtcattgcag aatgggtgtg acaattgacc aaaccaggca taatccaagc
     9481 tccctgatag tctataatct gctcagcttg ttctaaaaac gctggcttat cttgaccgac
     9541 atagacgatt tgagaatcct tgactgctaa gattccatca agataaacat ggaaattttg
     9601 atcacaagtc acgatattta catgctgaaa gactttcatt atagactcct tttttaaaag
     9661 acaagttgta ctctcttcaa accacttcag attcactttg ccgtaggtgt ggttactgac
     9721 ttcgtcagtt ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc
     9781 tgcaacctca aaacagtgtt ttgaactgac ttcgtcagtc ttatctacaa cctcaaagct
     9841 gtgctttgag caacctacgg ctagcttcct agtttgctct ttgattttca ttgagtatta
     9901 cagtgaacaa tttttctagc tattgtaaca aaaaagtcac tcgaaggcaa cttttttcgt
     9961 ccataaactt tcaaaagaga atggcttatt cagaactaaa agccgcagct ttttgcattt
    10021 ggtaatactt accctttcta tccatgagtt cttgatggtt accatattca acaatatcac
    10081 catctactaa gacaagaatt aaatccgcat cctgaatggt tgacaaacgg tgagcaatga
    10141 tgaagcttgt gcggcccttc atgagttttg caaaggtatc ctgtaccagc acttctgtcc
    10201 gtgtatcaat ggaagaagtt gcctcgtcta agataagaat ctttggaata gccagaaaga
    10261 ctcgggctat ggtcaagagc tgagcttggc cgacagagag agattctcca gcattttcca
    10321 acttggtatc gtatccctgt ggcaactgtt gaatgaaaaa gtctgcatta gctgctttgg
    10381 cagcagcaat tacttgctct cgactggctt caggattgcc aaaggcaata ttatcatgaa
    10441 tggtcccttg tgtgagccag gtttcttgaa gcaccatacc aaactgctgt ctcaatgatg
    10501 ctcgtgtata atcataaatg gattgcccat ccagcaagat atctcccgag ctaatgggat
    10561 aaaaacgcat aaggagattg ataagagttg attttccagc acctgtcgga ccaacgatgg
    10621 ctatcttact accagctgga atatcgatag acaagtcctt aatcaaaatt ttttcaggat
    10681 ggtagccaaa agagacatgt ttaaaggaaa tagctccctt aacttggtca ctggtcaaga
    10741 cttccttacc tgtttcagcc acttcagggc tatctaagac tccatagata cgctctacgc
    10801 aagccagagc actttgcaac tcagctagca ctgaagaaat atcgttaaag ggcttggtgt
    10861 attgctgaac atagttcaaa aaagtcacta aacgaccgac ggtcaaggct gaacccatca
    10921 tgatacgata agctcctact ccagctaaaa gggcataaat gagtgcattt acaaagcgag
    10981 tcgaaggatt gaccgttgaa gaataaaaga tggctgactg agaatagcct gagtagttgt
    11041 catgagcctc acgcaatctt tggataaatt ctgtttgagc attgaaggac tggattatag
    11101 tctgctggct aagcgattct tcaatcaact gagtctgaat tcccctcgtc tctgtttgct
    11161 tctggaagag atgataggat ctcttggcaa taaagcgtga aatcaccatg gacagtggcg
    11221 tcaacagcaa gactaagaga gtcatgagga gatgaatttg gagcatggct agaatactaa
    11281 ccaaaatcat caaaacacca atgaaaaatt ggttaaaaat catggtcaag ccagctgcca
    11341 actgttcgat gtccgtggtt acacgactga ccatctctcc attgccttgc cgatccgcaa
    11401 aagcaatcgg taaccgatgg agtttatgga tgattcgctc tcgtaaatct ctggtataag
    11461 agaagattag acgattatag aggagaggat tggcccattg tactagagta tttcctatta
    11521 ccaccaagag catctggaga aaaatctgcc aaaaaactgg tgatgaacca gccactagga
    11581 cttggtcaat gacctgccca atcagaatag gtagataaat tgataagcca acttgggcaa
    11641 tagttcctag aaaggctagg aaaaggagga agggatggtt tgctaaatct acggctaaac
    11701 gtttgagcgt ctggtttaca gtttgtcgtt tcattctagt cctcctttcc atgttgggat
    11761 gcattgattt cacgatagac ttgactggat ttcatcaagt catcgtgctt gccaacagct
    11821 agcaactcac ctttttccaa gaggagaatc tggtcagcca tctgtaaagt cgaggttcgt
    11881 tgagagatca aaattaagct catgtttgga aaattttctc taatagcttt caagagcttg
    11941 gactcggtaa tggtgtccag tgctgaggtc gcatcatcta ggatgagaaa cggagcctgg
    12001 cgcaagactg ctcgtgcgat agacagcctt tgtttttgtc cacctgagaa atttcgccct
    12061 cctgcttcaa ctagagcatc caagagtcct tccttatcac tgacaaaatc cttagcttga
    12121 gcaatttcca aggcttgcca gagttcttga tcagtcactt cttgatttaa acctaaagtc
    12181 aagttggaac gaatagttcc cttaaaaagt tcgacctttt ggggaacata agcaatccaa
    12241 gaccgccact gctctaaatt acgaggacta gatccatctc gataaaggtc aatgctcccc
    12301 ttatctattg gataaagtcc aagtaagagt tgcaccaagc ttgacttacc agaacccgtt
    12361 cccccgatga tacctagaat ttgtccttga gtcatatcaa aggaaatgta tctcagagaa
    12421 ggctgggccg catcaggata ggtaaaagtc aattcttgga cttgtaaaac ccgaccactg
    12481 gtaacttgct tttgttctaa ttctgaatgg atgttttcgg gagattccgc aaagacctcc
    12541 tcgattcgct tggctgagat ataggactgg ttgagagaat ttatcaacat ggctagcttg
    12601 accaattcca ccaaaatctg taagaggtaa ttgataagag caatgagagc accttgactg
    12661 agcactcctc cttgaattga aatatagcct tgccagataa taacgagaag agttccattg
    12721 acaatcagat aggtcagagg tgttaataaa ctagaccaga aacctgtctt ttcttgtaat
    12781 ctagcataaa cttggttaag ggtttgaaaa atctgtaact ctcgtttttc ttgaccaaaa
    12841 gcacgaataa cccgcatccc ttgcaattgc tggcgcgttt cctgaaccag ttggtccgtt
    12901 ttctttctga gactactgta gagaggattg accaatcgag ataaccctac aatgacaatg
    12961 gtcaaaatgg caaccatgac taagaaccag aaagtcaact cagctgagat tcgataagcc
    13021 ataaaaatgg caccaaaaac gataatgggc gctcgtaaaa agagacgcag gaattgattg
    13081 ataccagtct gaatctggta ggtatccgaa gtcaagcgag taaccaaact agaagttgtc
    13141 agacggtctc tgctgtcctt tggcaaggaa agaatatgac gataaagatc gtttgtcaat
    13201 tccttagcaa aacctactgc tgcctttgct gagtaaaatt gagctatcaa ggccactaaa
    13261 acgccaatta ctgcaaagat aaggagcagg ccaatctgca tccagagatg accttgatct
    13321 ccctgaggta aagattggtc aacaatccca gcaatcacca tgggaaccaa gagctcaaaa
    13381 acagcttcta acagcttgaa caagggggct aaaattgatt ccttgatgta gggtttgaag
    13441 taagataata ggtgtttcat aaatcccttc tattcatatt ctagaaatga agaaagtggg
    13501 aagccccact ctctgtttta tttgtttaag taaggcaata gatagccata tcctgctttt
    13561 tccatctcat ccttggccac aaagcgtaaa gaagcagaat tgatacagta acggaggccg
    13621 cctaactccc gcggtccatc tgtgaaaaca tgacccaagt gagcactgcc tgaacgagaa
    13681 cgaacttcaa ttcgctccat tccatggctc agatccttgt aataatgaat caactctttg
    13741 gaaatcggac ggctaaaact tggccaacca caacctgaag caaacttatc cttggcaaaa
    13801 aagagtggct cacctgtcgt aatatctaca taaatcccct cttcaaaggt ttggtcatag
    13861 gcattggtaa atggagcctc tgtagcagct tcttgtgtga cacgataaga ctcttcagat
    13921 agactggcct tcaacacctc ttgactaggc ttttcatagt ttgctgcatc aatcaatggc
    13981 ttatcagcat cggtcacatc gatatgacag taacctgaag gattcttcct gagatagtct
    14041 tggtggtagt cttcagccag aatgtagtgg cgtaattgct ccacttctac tgcaatcttt
    14101 cgacccagca tgcgttcctg ctcctgcacc actgtgtaga tagctggcaa atctgcttca
    14161 tcctgataat aaatcccagt tcgatattgg cggccacggt cattcccttg ttgattgata
    14221 gatagaggat cgataactcg gaaataataa agtaaaatct ctctgagtga cacttccttc
    14281 tcatcgtaaa tcacttggac cgtttctgca tggtctgttt ccttgatcaa ctggtaattg
    14341 gtcgtttcga cttgaccatt agcgtagcca acactggttt ctagcactcc agaaatgcgt
    14401 gaaaaatatt cctctaggcc ccaaaaacaa ccacctgcta gataaatttc tgccatcttt
    14461 atttctcctt tatcacgttt ttaactaata ctcttcgaaa atctcttcaa accacgttag
    14521 cgtcacctta ccgtatatat gttactgact tcgtcagttc tatctgcaac ctcaaaacag
    14581 tgtcttgagc tgacttcgtc agttctatct gcaacctcaa aacagtgtct tgagctgact
    14641 tcgtcagttc tatctgcaac ctcaaaacac tgttttgagc agcctgcggc tagcttccta
    14701 gtttgctctt tgattttcat tgagtataaa cttcttttca caaaaaggat atgaaaccct
    14761 ctggttaaga gtttccccat cctatcttct attctttatt ttgcttctac acggacacct
    14821 tgggtatcaa ctctcaagtc atgcagtttt cctttgaaag gttgcttttc caattctgcc
    14881 ttaattgttg gcatcttgtc atgagaagcc agaaccataa ctgtcggccc agcaccagaa
    14941 aggtaggttg cataggcccc attttctttg gtcacttgct taatcatcgc aaattctctt
    15001 accaagtcct gacgataacg ctcatggaag aggtctccct cgattgcttg cccagcggtc
    15061 accatgtctc ctgccaacaa ggcagcaacc gctacattgg cgatagaact tgcagcaaca
    15121 gcttccttat aagacaattt tttaggcaag acactacggc tgtcgcgagt acgtaattca
    15181 tagtttggaa tgtaagctag aaaatcacac tctggaaagt ctgctacgat agcagagact
    15241 tgcccttcaa cagaacttgc aataacgaga ttaccataaa tggctggagc cacattgtca
    15301 ggatgccctt caatcttggt cgctaactgc aatttttcat ggtctgataa gttgagttga
    15361 cccagttggt tggctagttc aatcccagca acgataaccg agctggaaga acccaaaccg
    15421 cgcgccaaag ggacatcact ggtcattttc aagcgtcttg gttgcaagtc tggtacaatt
    15481 tgcaaagcga ttttgagcaa gagattacgc tcatcatgtg gaatccattt gccaatctgg
    15541 tgttcaatca gccactcatc tcgttcttcg cagacctcaa tttgaagata cttggttaca
    15601 gctacaccga ccgagtcaaa acctggcccg atattggcac tggttgcagg tacaataatc
    15661 ttcatcttat tctcctagca ccttgaaggt attcaagagg tcgaattctg aaaccttctt
    15721 caattcagct gagacatttt caagctgggc tttattaatc ttgtgtgtga tgataacgac
    15781 acgcgccttg tcaccctctt tgccatcttg aaggatttgc ttaaaggaaa tatcttgagc
    15841 attgaagatt tcagccaact tcaagacctg accttttgag tctggagcca agattgagaa
    15901 atagtagttt gctttgacat cttcaggatt tgccaagacc aagtcacggc tatattcgtt
    15961 gaagtctttg ccaatggtac catcattcaa acgacgaacg atacggacaa tatcagctac
    16021 aacacttgtt gcagttggtt tttgacccgc acctggtccg tagtacatag actcaccaat
    16081 accgatagat tctacaaaga cagcgttcat tacgccattc acactagcaa gtgggtgcgc
    16141 tttaggtagg aaggttggag tcacttctgc agcaatacct gaagaagttt cctcaataga
    16201 accaaccaat ttcactacgt aaccaaactc ttgagctaca gctacgtctt ctggtgtgat
    16261 attgcggatt cccttgtggg ctacatcatc aaaggcaatc ttcatgccaa aggcaaattg
    16321 gctcaaaata accatcttgt aggctgcatc aatcccatct acgtcattcg tcggatcgct
    16381 ttctgcaaat cctagacgtt gtgcttccgc aagagcatca tcgtaagacc agccttcttc
    16441 caccatcttg gtcaccatga agttggaagt tccgttgact actccaagca cgcgcgtaat
    16501 tttatcagaa gccaaggaat ttgctaaagt acgaagaatt ggaatcccac cagcaactgc
    16561 tgcttcgtag taaagtgcta ccttgttagc ttgagcgatt tctagcaatt ctgcgccatg
    16621 gacagctaaa aggtccttgt tagcagtaac aacgtgtttt ccagcttcca aggcacgagt
    16681 gataaaggtt ttagcaggct caatacgccc catcaattcc actacgatag taatatcctg
    16741 gtctgataaa atatcatcca cattggttac aaagttaaag tcattccctg ctgcaagcaa
    16801 gcgatttttt tcatcttcat ccttgaccaa taccttagca actttgatat ctgaatgtgc
    16861 tgattgattg atttttcctc cattttcctt taggaggaaa ggcacaccac ttgcaacggt
    16921 accaaatcct agtaaagcaa ttttaactgt catctttatc tcctcgaaat tttctaatat
    16981 agccattata acagaatttt gtgaaaattc ctattatagt aaatcactat ttcagtataa
    17041 aaagaaaaaa cgaatcagac gattcgctct tcttaaaatc tgaaaatagc tttccagaaa
    17101 ggattagccg attttttgca gattgagcac tgcatcgtga ctcatcaaga cttgaccata
    17161 ctcttgtaag actgagcgac tgatatcact atcgtctgca aactcgcgca tacgggccaa
    17221 cagccaagct ggatatgggc ttggatgatt ttcaatatcc actaaaatgg tcaaataata
    17281 gcgctcgttc attttgtaga gttcagaagt ttccatttca aaagtcactg tcttggcaaa
    17341 aactaccaag tcagccaact tagcaaaaga aaggatgtag tagatgtaag gttctttctt
    17401 actctcagct tcttgttcag cctgctcttg ctcttcttcc ttggcttcaa cttgctcaag
    17461 agattgaatg gcttcgatat catccttggt tttgtctgcg atgctttttt ccagggtttt
    17521 gataaattca tctggagaca tttgagccaa ttcttccata tctggcaaat ccgataagtc
    17581 ttcaaaatct agattttggt caatctttga cttggtcaca aagacatcta ccttatcagg
    17641 ttttggagtc acacggaagc tcaacatgcc tgtatccaga aagctatcag gcatctctag
    17701 ttcatccaag atagcataaa agaactcttc tgttttttct tgaggaacga gaaagtcagc
    17761 aatctccatt ccacgatcca tcaaatcctc taaagacatc gtgattttta aagttgtatc
    17821 actaatttgt ttcattttca ttgctagtaa cctcatactt tcagttctat ctattatact
    17881 agatttttac gattttatca aaagaaggct cctctatacg gatagatttt ccctagggtc
    17941 tttctatagg agactccaaa agaaaatttc tgcagacaga tagaaaaagc cttcaaaatc
    18001 agctcttagc cgattttgaa gaccttatac atcagaatac ttataattta aaggttgcta
    18061 caccaaggat agaacgattt aagtttctga gaatttgaag actttgctca aatttcttat
    18121 aacgagtcac tccgtactct tcaacaagaa ggactgtatc tctttccaaa agagatgata
    18181 catcctgtaa atctacaaaa tgcattcctt ttaaagcttc ttgactctgt ttcaatttat
    18241 ctaggatagc tttatttgag ctaacgatgg tcaattcctg tccagtattt ttgtatgaca
    18301 aaacatctgc taggttagca attgttgtaa tctctgttac aaaatcaatt tgatactgag
    18361 aaaaatcacc tactctattg attgttggat taaagagata aactaacaca tttcccatca
    18421 caaccaaaat cacacaaacc actccaataa caactaaacg aagaatcaga tttttcacat
    18481 ttaagccaag cgctgtttca ccatttgcgt tcaattcttt agagttgatg gtttccagtt
    18541 tttcaatttt cacatttgca taggcatgtt taaatttctc aatcaaccca tcaatttttt
    18601 tctctaacaa gtcattggca tctttacttg atgtcaaaat tttcacacca acccctgcat
    18661 cgtcaatcat atagtagacg gtcaattttt tccaccaata gtcattcgtt gaatttttca
    18721 aggttgtttc tgtcgtgtct aattcactgg caattttttt caactcactg ggttctacat
    18781 cattgaaaag ataagctcca ttcaaattac catcaatcaa tttcccataa aaatcactat
    18841 aaccaccaat ttgatgattc aaaatcgttt tggccgactc ttttggagga gtgattttat
    18901 agataagata agttgaataa cttgttgtat ctttgacagt gtttttattc ctaactgctt
    18961 taattgtaaa tggtacagca atgagagcaa ataaagcgat gagagctaaa atatttgctt
    19021 ttcgcttttt ataaagattt gcaaacaaat cagctactga ataatgttca aacatgattt
    19081 tttctccttt gtttagtaga tactagtttt cctttgtaag catttttgct acaaatataa
    19141 tcacaagaac aattccccag aattgcattg taaataaatt gaagaaactt tctgaaaagc
    19201 tgcttcttgg cataaagaat agattattca agatgagtag ggataaagca aataggattg
    19261 tccttgagcg ataggctact tgcagcatgg ctataaataa tacgccgagt aagaaactaa
    19321 gcagaaagac tccaatcata ccatagtcgg tatacaactc catgatataa ctacttccga
    19381 taccatgccc tttcaagtat tccttgttca agacaagata ggatagattg tgggcataac
    19441 tattactatc aatagctagt tccacactat tggttgtatg ttcaaaggct tttcctccga
    19501 aaatggctcc caaactcccc cttgcaaaat aatcaagaac aggaccaaaa gtaaaattac
    19561 ggaaatctcg gtaagggagg ctactgttaa atagaaaacc tcgagccaga acaccaaaac
    19621 tagtcccttg tttatagata aagtcaagta agatatccca gaaacctgta tgagaaactt
    19681 ggacattatc ccgtacataa ttgagtactc ccatcgctaa catgagaata ggagaaccta
    19741 caaaaatcgc taacttttct ttaaacccaa tccattttcc tttttcagtt tgctcccgca
    19801 taaagtaata aacaaaagca aataaaatac ttaaaataaa gggatttcgt gtcccaattg
    19861 ccaaatgaat agtattagct gcaataaagg agacaagcac tgctgtggcc tgcaatttct
    19921 ttggcttggt tgccagatac atacacattg catagaccgt aaaggtagac aaaatgtagg
    19981 taaaataagg cagtttactt tcaaaatttg catagtaggc atagtaggaa gtctgcaaac
    20041 gatacaagag ccgttcaaat aaccgaatga aatagaaagg ataggttaga agaaaaactc
    20101 ctagtgatac aaagcgtaac cgcttgatat aaacctcttt tagagaattt cctatatttg
    20161 ctacttttat tttcttccta gctatgaagt aacgagccag aatgcctcct gtggtcaagc
    20221 ccagaatcga aaccatgaca actataaagg caaaacgata ggctattgga tgataggtat
    20281 ccaaagcacc atccctaaaa taatcaatgg tcggtcttga taccagaaat acaaaaatgg
    20341 ttaaatagaa aataaaatgg attaagtaat acttgatatc attccaacaa gcaattaagc
    20401 tactaaccaa caagaacaat aaagtagaaa gtaagctaac attattatta ttaaacagat
    20461 acacaattcc acttactagc gtcaaggcat aactgactat ggtcaaacta aataataatc
    20521 gtttcccatc aatcacttgg tcacccccgt tctaatgtaa ttttttagat ttttcaatat
    20581 ttttcagtaa taagaatcga tataaggaaa tatttatgaa tagggccaaa gcactaattc
    20641 ttctcccctt acggaaaatt ggattcctag aaatagcaaa ggcatggcct tttaaaaaac
    20701 gatgaatctg agaataggct tcaaactgtt tatactgatc atctagcaac atcttatcca
    20761 gaataaagaa gtgggcatag gccaatctga aaaaagcgac ctctttcaag tcaggatagt
    20821 ttttcacaac ttcattataa aacttttggt agatatcaat ataggctaaa tccttctctg
    20881 catagggttt ggtcgtaata ctatcccctc tatggaaata gtaataatag ggtttagtat
    20941 taaccacata cttcttggcc aacttgatta aatcaaaatg gtaataggca tcttcgtaaa
    21001 tcaacccctt aggaaaggat agggcagttg caatctgtct cttgattagc ttattgcaaa
    21061 tcgtcccagg tattttttca cctatgaggt attcctttag aaatgtttga gaatcacaga
    21121 caaaatagtc atcctgattg gctgactgtg ggctttcatc attagcatag acattcatga
    21181 caccacagct tgaaacatcc gcatcttctt gaactaattg ctcatataag ctctgaatca
    21241 tttctggatg gatataatca tctgagtcaa taaaaatcag ataatccccg tgagcctgct
    21301 tcatcccatc atttcgtgct tgcgacaatc cttcgttctt tttatgaagc actgacaccc
    21361 tgtcatcttg ttcagcgatt gaatcacaca agcgaccact ttcatctgtt gcaccatcat
    21421 caacaagaat aatttccaga ttttgatagg tctgcttctg aatggaagct atcgattttt
    21481 ctaggtactg cgccacatta tagactggca caatcacact aattaatgca gtttccatgc
    21541 tactcctcta atagtttttc tacttgttcg atttgttttg taattgtaaa ttgttgaatg
    21601 aattggctag cctcatcgac atcaaagttt gaggcagaag tcatgtaatt agtaatcgcc
    21661 tgagctgcct cttgattgct ctcaatgatt tgtccaaatc gtccttcttg ggataattcc
    21721 tcagcccctc caacgttcgt agagataaaa gggagtccca gactcaaggc ctccacatac
    21781 actccaggaa aaccttcttg tttagacata gacaaaagaa ctttcgtctg agatagatac
    21841 tgataaggat ttttttgata accaaggaaa tgtacatagt cctcaatccc atactctttg
    21901 actcgttttt tcagttcctc ttccatatca ccagccccga taaaatagag atgatagttt
    21961 tttccctctt ggtgtaataa tcgtatcact tccactacac ggtcagaacc cttattttcc
    22021 tcaatccgtc cgatagtaca gatactttga ggagcaatct cgatatcgat cttctcttga
    22081 gatttttcta gaatagtctg aaaatcatat ccattgtaga ttgtctgtaa tttagaagta
    22141 taatctggat aaacttcctt gatagaattg ctggtctttt ttgaaatccc tacaattgta
    22201 ttcgcagcat ccaactggct tctatgtgat tctcttttag agctatcctt aagaagttct
    22261 tcaatacttc catgaatcca agatatcttc ttgacttctc ttcttttaga gaacaacagt
    22321 ggtggattca taatggtaaa agaaacttca acatcataat catcttttac aagcaaacga
    22381 cgagccagtc ttggaaaata aattctcatt ctccacaaaa aagctcgtaa ccatctggtt
    22441 tggcgataat cttgaaggga ttttaaaatg cgtacatgct ttggaacaga ttcatatccc
    22501 ttgtcaaagt gctccatttc aagaatatca atatcatact tttctggatc cagatttgaa
    22561 acaatggttg atagaatctt ctctgcacca cctccaagag aaaaagacca cataaaaaat
    22621 aagatttttt tcttagccac catattctcc cttgtattct gtataagact tatccatatc
    22681 agcgatgaca gcatcatgat gcggtacctg cttgtctgct ggtggaggcg tcatataatc
    22741 cccaaaagca gttctgagat agacatcata gccgattgga ataggcatct ctgttccttc
    22801 aaatggcaag aaaagattgt cttcaaaaga tgtgattggg tacttgtttc tcatgtagcc
    22861 aggacctgag cataattctg taatgccatc acaatcagcc aaatcatact tagtcatttc
    22921 tttctcagct tttttccaga tgcgataaca gagagatttt ggagtcaaac ccagtaaaat
    22981 gcgacttccc catttcatga gagcaccatg cttttctgga atagtttgcg cacaaaagag
    23041 tgaataaatc aaggcccaac gaacctgttt tttccgctca gctggatttt tcggataata
    23101 atccaaaggc aaaacatcca aggccagacc atgtggcaaa tccaaatcct gctgataagg
    23161 cttgatacag gtggtttcct tgtcacgaat ggtaataaaa agattacgat caacaaaatc
    23221 cttgtgactc tttgacaaga aataacgttc atctgcataa cgaggccata attctgctaa
    23281 tttctcataa tctttacgag gcataaaaaa gtctaggtcg tcgtcccaag gaataaatcc
    23341 cttgtttcga agggcaccaa tagcgcctcc gccacagaga taacagagca aatcatgttc
    23401 tttacaaaag gccacaaaat attcagccat ctccagacta cgagcctgaa ttgcttttaa
    23461 atcagtcata ttgttcatta ttctttctat cgtatcgttt cattatacca caaacaaggg
    23521 gtgaaaatct attgcagact gtaaaaaatc aaagcctgac tgctatccaa atagctatca
    23581 aactttgatt tttctgtctt atactcttcg aaaatctctt caaaccacgt cagcttcacc
    23641 ttgccgtagg tataggtaac tgacttcgtc agtcttatct acaacctcaa aactgtgttt
    23701 ttagcagcct gcggctagct tcctagtttg cactttgatt ttcattgagt attatcttat
    23761 ctcaagccca tttgagcgag cttggtttga tatttgtttt gatcaaccag caagcccaag
    23821 cctccataaa catcataggc atctacccag tcacccagtt ctggaatcgt caatttttca
    23881 ataccatttt ttgctccatc caaaacagat aaaccgtttg ttaggaggaa agtatagggt
    23941 acgttggttg aggtcatagc aaaaaccttt ccaagagctt cagaaccagt gaaaagttta
    24001 gtgggatctt taatttgctc taaaattgct gttaaaactt gttgctgtct ttttgtacgg
    24061 ccgtaatccg cctcatcatc atcacggaaa cgagcataat tgagcagggt cgagccattc
    24121 atctgctgtt ttccgacttt aatggtttgg gttggagact cagtctcggt agcgtataaa
    24181 tcatctccga ctgtagcttc tgttagggga cgcccattca atgttgaaaa ttgagcatca
    24241 atcgtcaccc catcagggaa aagcgtgtca atcgctgtgg caaaggcctg gaaatcaacc
    24301 aaggcgtagt acttaatgtc caagtcaaaa ttatctttca agacttggcg aaccatttct
    24361 gccccttttt gcccctcttg ttctcctaac tcgtaggcta cgtttaactt gttatctgtc
    24421 tgttttctac cgttaatcac ttgactataa ccatctatat agaccaaatt atcacgcatg
    24481 aaactgacta gcttcatttt cttatctgag cccccgacat ttaataccat aatagagtca
    24541 gttcgtgtct caacactgtt ctggccgatt cgaccatcag tacccatgat taaaatatta
    24601 actccatctc tagtgtcctg accattaaag acttctactt gagctgcccg ggcatcagca
    24661 gttttctttg cgctagcatc ttggtaacca cgcaaaaaca tgaataccat ggccaaagcc
    24721 acacagacca aaagtgaaaa aatcaccata aaaattcgtt taagacggag cttccgtctt
    24781 ttcttttttg gagggaaaga gagtgcttgt gatttggatt gtgagcgact ccggttcgca
    24841 tagcttggta agtcaacctg ctcttctctt tcttgttcca agctagagct actatttccc
    24901 ctagcaagag ttagcttttc ttgcaaatag gcaaactcat ttttttctct ctcattgaga
    24961 tagtgaatat tttttagcaa ataatcataa cgcaactgct catgatgact taagggattt
    25021 tctttactca tcttctctcc tttccatggt ctgatattgg ataaatagga taggcaccca
    25081 gaattttata ctggattcca atcgcttcta attctttttg ggcaaagtgg accaagtcct
    25141 tatcggtata atccacatcg ataatgaaaa agtattcacc cagtgctgtc ttgagtggac
    25201 gactttcaat ttttgtcaag tcaattcctc gccaagcaaa ggtcgacagg gccttataaa
    25261 gtgcacctgg aaggttgtca ggtaatgtca aggccaaact catcttttca gtttgtgctt
    25321 gcaagggaat actaggcttt tcagctccta gaacccagaa acgtgtgaaa ttggcttcca
    25381 tttcctgaat atcctcggca atcagttcca atccatattc ttcagcagaa cttctaggtg
    25441 caactgctgc aaagggctgg tctggatgtt cggaaataaa acgggccgca taagctgtac
    25501 tagctgttac ctcgatttga gcctctggat attgttcatc gatgaatttc tttccttgag
    25561 ccaaggcctg tggatgtgaa aaaatctttt caatcttagt atggcctgga accaccatca
    25621 actgctgatg aataggctga acgatttctg ctactgcttg gatgtgagcc tgatgaaaaa
    25681 gatagtccaa ggtttcatga acactaccct caatagaatt ttcaactggc accacagaat
    25741 agtccactaa tccttgctca taagccttga tgacatctgt aatgttagca aaagcctgca
    25801 attcctcatg aggaaaagct atctgcacaa cgtggtgtga aaatgatccc ttgggaccta
    25861 gataagcaat tttcatctta gttcctctat aatttcctct gggcttagct tggtcacatc
    25921 caaaacccga ctagccactt cctcatacca agcctgtctt tcttgaaaaa tagctactag
    25981 ttcttccttg ctattattta gaaaaagcgg tcgctgattg tccttatcag ctgcgatacg
    26041 ttggtagagg gtttcaaaat ctgctttcag gtagatgtta tctgtattag tcttgagtaa
    26101 gtcacgattt ctctgagaaa taaccactcc tcctccagtt gacacgactt ggtctgtttg
    26161 tagtaaatca gctaggactt ctgattctac ctgacgaaag gctgcttctc ccttttcagc
    26221 gaaaaaattc gcaatggaca tacctaggcg cttctcaatc agagcatcca tatcaaggta
    26281 attagggtcc aagcctcttg caatagtcga ttttccagcc cccataaacc ctaataacac
    26341 cttagccatg aatcaagctc tccaaatcat caaagaaact aggatagctg gtattgatgg
    26401 cttctgcacg gtcaagctcc acctctccat ctgcaaccaa gagggctgcg atagctgtca
    26461 tcatgccgat acggtggtca ccaaacgtat tgactctagc accgtgaaga gctgatttcc
    26521 ctttgataat catcccatct gccgtaggag taatatctgc tcccatacta tttaaggcgt
    26581 ctgccacaac ctgaatacgg tctgtttcct tgaccttgag ctcctcagca tccttgataa
    26641 ctgttacacc ttgggcttga gtcgcaagca gggcaataat gggcaattca tcaatcaatc
    26701 gtggaatcaa agcgccacca atctctgttc ctttcaagtc agaagactca acagtcaagg
    26761 tagaagattt agcgactgga tcgatttcag ttatttccaa ttttccaccc atggcacgaa
    26821 tgacatcaat aataccggtg cgagtttcgt tgatccccac attctgcagc actagacgag
    26881 aatttggaac aatcaaacct gcgactaacc aaaaggctgc actggaaata tctcctggta
    26941 cgaccacctt ctgtcctgtc aatttttgtg gcccttggac tgtgattttc ttaccgtcca
    27001 cacttaaatg accaccaaat tgtttcaaca tatcttcagt atgattacgg gtgcactctt
    27061 tttcgataat aactgactcc cccttagctt gtaaggctgc aaacatcaag gctgacttga
    27121 cttgggcaga ggcaattggc aactcataat gaataggtct taggtttttc gtccctttta
    27181 agcgaagggg aggcaagtct cgttcagttt gccctgaaat gctgacgccc atttttttca
    27241 gtggaagggt cacacggtcc ataggacgtt tggaaagact atcatctcca aacatctcta
    27301 cttcgaaatc tgcaccagca aggacacctg aaatcaggcg aatcgaggtg ccagaatttc
    27361 ccatattaag ggcattttgt ggcgctttta agccagccat gcctacacct tgaatggtaa
    27421 taaccccatc tttatcctca atttcaacac caaggtcacg aaaaacctgc atggtcgaaa
    27481 gaacgtcttc acctcgcaga atatcataaa ccttggtctc accctcagcc aaacttccaa
    27541 agataatgga acggtggctg atagacttgt cacctgggac gcggatacta ccatgtaaat
    27601 ggcgaatgtt tgtttttagt ttcatactgg acctcatact tgcaatactt ttacctattt
    27661 tatcataaaa agccagaaat tccttaaaaa ttcctgactt taggatcgtt cttttcttat
    27721 ttcagcaatt ctgaaactgg ttcaaaaaca attttttcaa tgtcagaaag gtaaatggcc
    27781 aattgttgtt gcttggtaaa gaattctgac aagaggctat ttccttgaat ctgtttacca
    27841 aagccttcca tcttagcttg gaaggacgca tctggcattt gacctgtatg tgctagtttt
    27901 tgaatttcct cttgaaaggc aagatattct gtaaagattt tgcttgcctc agcatctgct
    27961 gcaatcgcat ctttagctgc tttaacagcc ttgtattctg gtaatccgcg tagaccgcga
    28021 ctgagttcgt ttgcactatc gtaaatattt gacatgttct tctccttatt tgatgacgac
    28081 tgtatagtcg gtattttctg ttatgagatg ctcagctctt tccaagtctt gagcattttt
    28141 aaatgaaatt tgtaggattc cgtgaatatc ctcacgattt tcctcgttga tgtggatgtt
    28201 aaccaaggaa gtcccacgta gcagttccaa aatccgcagg atgacatctt cttcatcagg
    28261 aacgtcaaca tagaggtcgt aagagctatc cacaccacca cgcttatgga tttccatggt
    28321 ctggcgttgt tcacgcgctt ggttaaaaaa gttccaaatt tgctcttcat ctcccttact
    28381 aatggcctga ccaatcactt ccaaacgttc cttgaaatcc tcaattctat ccagaatggt
    28441 ctcgctattg gacaagagaa tggaggtcca cattcctggc tcgctttccg caattcgggt
    28501 catatctcga aaaccacctg ccgcaaagcg ccttgccatc tcatgctctt gagcatagac
    28561 cgcagtctgc tccatgagac tagaagccaa aatatgagga aaatggctaa tctgagaagt
    28621 gacacgatca tgctccttgg catcaatctc gataaaacga gcatgaagac ctgaaagcag
    28681 atccttcatt tccttaagcg tgtcctgact tgtcaggctt gaaggtgtaa agatataata
    28741 ggcattttca aaaagattga catctgccga agcagcccct gtcttgtgac taccagccat
    28801 gggatgggcc ccgacaaagc gaacagactt gccagccaaa tactgctccg ccgcatccac
    28861 aatggttgac ttggtcgaac cagcatctga aataataacg ccttctcgca aatccaaatt
    28921 ggccaactcc ttaatgaaag caatagtttg tttgattggc aagctgagga taatgacatc
    28981 tgccaaagga gcaaaactag caaaatcatc cgttgcacgg tcaatcatgc cttctttcaa
    29041 ggcgatatct ctcgaagctt gactacgatt ataacctaaa atttcataat ctggatgatc
    29101 gcgtttgata ccaagtgcca tagaggctcc aatcaaccca agacctgcga tatagattgt
    29161 ttttgccata ggaactcctt aatagttctt tgtatagtct cggtgtttgg ctaccgcttc
    29221 ttttagttcc tcaagattat ctgatgagaa tttttcgagg atttcttgcg ccagaaccgt
    29281 tgctacaact gcttccatga ccattcctgc agctggaaga gcagtcggat cacttctctc
    29341 cacggttgcc ttgtaaggtt cgtgggtttc gatatccaca ctcataagag gtttataaag
    29401 agtaggaatg ggtttcatga ccccacgaac aacgatgggt tgcccattag tcataccacc
    29461 ttcaaaacca cctagattat tggtacggcg agtataaccg tcttctttag accagagaat
    29521 ttcatccata acttggctgc ctttacgata accagcctca aagccaagac caaattccac
    29581 ccctttaaag gcattgatag agacaacagc ttgagccaat cttgcatcca attttctatc
    29641 ccattggaca taggaaccaa gaccaactgg aacgcctccg acgactgtct ccacaacccc
    29701 accgatggta tcaccatcac gtttgatttg gtcaatatag tccttgattt cctgttctcg
    29761 ttcttggtta acaatagaaa cttcagactg ggcagctctt tgcttaattt cagcgactgt
    29821 cagattttca ggaacatcga tttccttgcc accaaagacc acgacatggt tggcaatctc
    29881 catatccagc tcagccaaga ggcgtttggc tactgcacca actgccaccc gcatggtggt
    29941 ttcacgagct gatgaacgct ccaaagaatt tcgcaaatca tcaaaacggt acttaatccc
    30001 cccaaccaaa tcggcatgac ctgggcgagg atgagtaatt ttccgcttgc ttttaaggcg
    30061 gtcttcaatg tcctccgcag acatgatgtc cagccatttc tggtggtcct tattgatgac
    30121 atccatagta ataggcgccc ctgtcgtctt cccgtggcga acgcccgaag taaagacaac
    30181 ctggtcactc tcaatcttca tacgaccacc acgaccgtag ccaccctgac ggcgtctaag
    30241 gtcctcattg atatcctcag ctgtcaatgg aagtccagct ggaattccct caataatagc
    30301 tgttagacgg gggccgtgtg attctcctgc agttaaatat ctcatacact ctccttattt
    30361 taccaagtag tctttcatct cttccagaga aactgggtga atgatcgctg aaccaagctc
    30421 tgacaccaag accaatttca aggtgttacc acgcgttttc ttgtcatgag taagagcctg
    30481 ataaagcttg tcaacttccc aattttcata gtcaacaggc aagccgaatt tctgacacat
    30541 ctctgtgata gattgggtaa tgccagctgg catgaggcct ttttcctcag caaccttgga
    30601 aatctgtacc attcccatgg caacagcctc tccatgcatg accttgccat aaccggcagt
    30661 cgcttcgatg gcatggccaa tagtgtggcc aaaattgagg taaagacgaa taccattgtc
    30721 caactcatct tcaaccacca tcttgcgctt cacctgacaa gaatgttcaa tcaaggtctc
    30781 tgcatgttcc aaaatgctct caacagaacc attcagttcc gtcaagagag cccacagttc
    30841 tggatcctca atcaagccat acttgataac ttcacccatc ccttcaatca actctctttt
    30901 tccgagggtt tcaagaacaa gtggatcaat cagaacccca tctggttggg caaaggtccc
    30961 caccatattt ttagcaaatg gtgtgttaac gcctgtcttt ccaccgatag aagaatcaac
    31021 ctgagctgtc aaactagtcg gaatctgaac aaagtgaata ccccgcatat aggtagaggc
    31081 tacaaatcca gccaggtccc caacaacgcc accaccaaga gcaacgattc catcgctacg
    31141 agtcagacct tgcttgacta gaaattcata gactttctga acagtagtta aattctttct
    31201 ttcttcacct tctaagaaat caaaaacagc tacctgaaaa ccagcatctt ctaggctgag
    31261 cttgaccttc tctgcataga gagaggctac atggttatct gtcacaatga ctaccttttg
    31321 cggttgccag agttctcgca accactgacc agcctgggcc atacaacctt tttcaatctg
    31381 aatatcataa ggatgatgag gaatatcgat tctgattttc ataggagagt ctccctttct
    31441 ttattggtat ttttctgtta aagactgcca aatctcttct gtcggcattt ccttgcctgt
    31501 ccacagttga aaagcttctg cagcttgata gagcaacatt cccagaccat tgactgctgg
    31561 attgccctga cttctagccc atttcaaaaa cggtgtttca aagggttggt atatgatatc
    31621 tgcaactaag agagtttctg gtaagactat gttttcagga acaggagagg attggccatc
    31681 catgcccaca ctggtggcat taactagcaa atccgactcg gcaatccttg cttgcagttc
    31741 agaaacattc tctaaagcac acaaatccac tttaaaacct gtctgctcct gtaacttgtc
    31801 taggtaaggt cttgtttttt ccatagaaac ggaacgaaca aagaccgaaa tctgactgac
    31861 gccatccaaa atagcctgtg ccaagattga tttagccgca ccacctgcac ccagcagggt
    31921 catcttttta cctgaaattg taaaagaagg caagcactta aaaaatccct tgccatctgt
    31981 attatatcca attaaattgc cattctcatt gacaaccgta ttaaccgcac caatcaagcg
    32041 cgcttcatcg ctcagcttat ccaaataagg aatcacctgc tccttatagg gcatggacag
    32101 attgatgcca aacatctggt agcgacgaat attggccact gtttctgcca agtcactcgc
    32161 ttcaatctcc caagccacat aagcaccgtt ggtagctgtc gcctcaaagg ctctattgtg
    32221 gatgaaggga gaaatagaat gcttaatagg attggcaaca actgcagcta aacgtgtata
    32281 gccatcaagc ttcatccaaa atctccctga tttttttcat gctagctaga gaaatctgcc
    32341 caggggcact aacctcatcc agactggcaa aagaccaact cgaaccagtc acatccgcag
    32401 tgatacgaga gaccttgccc accttaccca tagaaatggt cacatattcc tgttcaggat
    32461 tgagggtttt aaagcctcgt gtatagttca tcaagtctaa gacatcctgc tccgtgtgag
    32521 ccatcaccgc aaccttaaca agttttggat ttaggatcgt caactctgac aagatttcca
    32581 tcatgttctc aggtgtttct tggaaattat ggtaactcaa aacaagattt gggaagtcca
    32641 gcatttcctc aaaaacatcc ttgtagctat agtactcaaa atcaatatag tctggttgat
    32701 agaattgcgc aacttccttg attagatgga tatactcttc tggagaaagg tcgatttctc
    32761 caccttcgga gcgagttcgt agcgtgaaaa ccaactcacg gcctgcgaat ttttcaaaaa
    32821 tggctggagc tacctgcaaa atcgcttctt taggcagata gtcggcacgc cattcaatga
    32881 tgtcggcatc caggtacctc gtggcatcca gagcctgagc ctcctctaaa cttcttggca
    32941 ttactgaaac gattaatttc atttactaac cttcatacta atcaccttga ggtaattact
    33001 actttcatct tttttattat aggcaaaatc tgctggaaga ccatatttgt ttaaaatctg
    33061 gtaacttctt cctgcaaagc ctttatcaat ttgttctgta aatttctgac gggaaacatt
    33121 ggcagcattg gtactggcaa tgataatccc tcccggattt aaaatctcaa gactctggga
    33181 aatcaacttg tgataatcct tggccacaga gaaagtttgt tttttattcc gagcaaagct
    33241 aggcggatct aggacaatca catcgtaggt caagtctttg cgtttggcat atttgaaata
    33301 ctcaaagaca tccatgacta taaaacgatg ctcgtctgtg ctgagcccat ttgcctgaaa
    33361 atgcgcttga gacaattctc gtgaacgttt ggctagatca acagaagttg tctggctagc
    33421 tcctcccatg gccgcagcta ctgaaaaagc cgctgtgtag gaaaacatat tgagcaagga
    33481 tttacccata gccaagccgt caactaaact accgcgaacc tcatgctggt ctaggaaaat
    33541 tcctgtcatc aagccatcat tcataaagac ttgatacagg acaccatttt ctaaaacagt
    33601 gaaaaagtca ggtgcttctt gaccataaac atgggcagat tcatagtcaa aacccttaaa
    33661 gcggattttc tcataagccc ctaaaacctc agggaaaacc tgtctaaagg cttctgatat
    33721 agtctgacga atctgataaa cataagagtt ataccaagaa aagacggcgt agtcgccata
    33781 aaggtccact gtcagacccc caaagccatc tccctcttga ttaaagagac gaaaggcagt
    33841 tgtcaaatca tcttgatagt aggcgtttct cttttctttg gcttttctaa acaacgtttc
    33901 aaagaaagtt tgattgaagg ccaccttgtc tttgctgaca aaccagccca agcccttgtt
    33961 ttgctgagaa aggtaggcag tcccaagaaa gtttccttcc tgaccctgca cctctacttc
    34021 ctgatcctta agattgacat tctcaagatc actggcttct agtaaaacta gccccttagc
    34081 aagcttcttt tcaacccttt tgctgactct tattctattc ataactacca ttatatcaaa
    34141 cttttagaca attctcaaaa aagaaactac ccttgctttt ttactcttct tttaaaaaat
    34201 ggtatactag acttcctgca aaactaggaa ataaatgtgt aagaatcaca ataaaaaatg
    34261 ctcttccgtc ttggaggagc atttcttttt atcaacgaaa atcaaatagc aaactatgaa
    34321 actagcctca ggttaaccgt gagattatag gtagagaggt tgtatcagca atatgtgtct
    34381 gtcaaattta gtgacaaagg tagtagaaga aagatgaaga aataaatcag cttcagtagg
    34441 tatctggaaa atttgatttt atagagaagc cttttgttac aaactcaata tactatcaat
    34501 aaataatatt atagaagcaa caataattaa aatttcacct atttgcatca ttctatttcg
    34561 aactctaaat atatgttcta tcaaaaatac ttggatcaca cacattatag gaattaacgt
    34621 ttttgaaatt gaaaaatatc ccaataaata aactataaac aacaataata gaactatatt
    34681 atatttctta ttcaaaacat tcctccctat atttttgatt accaatctta atcatttaca
    34741 actacattct aacaaactat aaaagcgttt gtcgaattga atttatcaag caagcaacca
    34801 actatctcat cttttttcta tttctgccaa tatgcgtgac aggtaataat gatagccaaa
    34861 aatagcaaga gcaagcaaga cgataagagc tcctactccc aagttgatgg caaggatagg
    34921 ggagagagac tgaaccaaga atatgctccc aattacaagg gccatcagga ttgcactata
    34981 aataaacaat aaaactatgg cgactatgcc atttgaacga ttcaccaggt ccgtaatgct
    35041 actccaattg gttgacagat ttttaacgtc cttaaagtaa tggtggcaag aaaggatgac
    35101 actggcaatg atccagacta caagaaggta aatcatcgaa aggatggaca agcctagata
    35161 tagagaaaga ccgagcaaag tcagaactgg taaaaaggac tgaacagcaa agataatcca
    35221 aaatttcact ttcacataac gagcaaagtc aaagggtaaa ctcttcagaa aatcaacatt
    35281 ttccctctcc aaggacaagg caattgaatg caggctggtg atattgttat tgacaactgc
    35341 tataaacact cctacaaaaa acaagggtaa ccagtatgga ggatgaatgt ctggaactat
    35401 ctgagaatct cggattttgg aaatcagact gatcatcatg agataaggaa ggaaagcact
    35461 tgtaaaaagc actgtaatca caccagtccc ctgtcccaag agggtgaggt ggtagcgtaa
    35521 aaccatacgg aaaaagccct ttttagtagt tgaaatcctc tccttgctgc gacgttcttt
    35581 tttgaccttc tcctcactgt taagcaggat cacgtcataa aaacgaggaa ggaccttctt
    35641 tttggtcaga taaagcagga agagagttag tcctatccaa gcgagcagac ccactaaggc
    35701 ttctgtcgaa aaaggctcca ctgctatttt gtaaaagata tgaagaggat aaaggagaaa
    35761 tggaatgtct ctaactttgt caacaatact tccaaaagtc gactgaagaa agaagataaa
    35821 tattaaaggt atgagaactc ctatcccaat catcacattc gaaaaaatag actgatactt
    35881 tctgaagacc ctagtctgag ccaagaaatg tactgccact accgtcacta aagtaacaga
    35941 gacaaataat aaggtcaagg acagtagcat caaaggcaaa cccagccaaa gagaaggagc
    36001 tagactaata tagagggcta gaaaataagc taggattggt acaattccag ttagagctgg
    36061 caagaggaca gacagacctt tggccattat aatctctgat tctttaaagg catagggcct
    36121 ataggaggcc aggtccttac tctcataaaa gacattgtaa aaggcagtga aagaagttga
    36181 aaaggccagc accagtaaaa tagcaaccat cgagctaaaa taaataggca tttcctcaaa
    36241 aggaaaatga atggctatat tactaaaaca gatgagcatc aagagactgg aaaaaatgta
    36301 agaacttagg actctagcag aaacatttac ttttttccca ggattcttag cctgcttctt
    36361 tcgtagatta gccagattag cttcttgaga tgaatagagg atattgatat caactaattt
    36421 tttaatgacc ttgagacgca tccgcaacct cctcttttct accagcaaga ctaaggtaga
    36481 tactttccaa aaactggtct gggtggtctt tcctcaagtc ctctacctta ccacaataaa
    36541 tcaaatgccc ctttttcaaa atggcaatcc gatcacagac ttgctctgcc acctctagga
    36601 catgagttga aaacaagact gtcttccctt tttgtgcatg ttccttcatc atctgtttca
    36661 aatcaaaggc agcctgggga tccaaaccag tcaagggttc atccaagacc caaatatcgg
    36721 gatcagacaa gagtgctccg atgacaaaga ctttctgacg cattccgtga gaaagagttt
    36781 caataacctg atagcgattt tcagcaaaat caaaaacgtt caatagccta gctagactag
    36841 cctccaagtc agatctactc agatcatagg atgaggcgat caattcccaa aattcattgg
    36901 ccgttaagcg taaaaataag tcaggcgagt ctgctacgta gccaatcttt cgtttaatag
    36961 ccaagcgatt ttccgataac tcctgaccgt ctaccaaaat acgaccactg ctgggtgaaa
    37021 tgatactgac tagggatttt atggtggtcg attttccagc cccattatga ccaatcaagc
    37081 ccataatctc tccattttca atctgcaaat tgagattact caaggcctct ttatcaccat
    37141 acaacttact aacattttga aattcaatca tgggacaact cctatcttta tctgtattat
    37201 acatcgctat actagcactt tgatacaaaa aaatcaatac tttattttaa gtagttaaaa
    37261 tagtttcctt ctatcttacg caaacgtttg caccaagaga tactttatga tagaataaag
    37321 aacaagattg acaagtaaga ggaaacatca tgcaaaatca aacactcatg caatactttg
    37381 aatggtatct gccccacgac ggtcaacact ggacgcgtct ggctgaaaat gctccacacc
    37441 tagctcatct ggggatcagt cacgtctgga tgccaccagc cttcaaggca accaacgaaa
    37501 aagatgtcgg ctatggggtc tatgacttat ttgacttagg agagttcaac caaaaaggga
    37561 ctgtccgcac caagtatggt ttcaaagaag actatcttca agccattcaa gcccttaaag
    37621 cacagggaat tcaacctatg gccgatgtag ttctcaacca caaggctgct gccgatcaca
    37681 gggaagcctt tcaggtcatc gaagttgatc ctgtagaccg tacagttgaa cttggagaac
    37741 ccttcaccat caatggctgg actagtttta ccttcgatgg tcgccaagat acctataatg
    37801 gcttccactg gcattggtac cacttcaccg gtacagacta cgatgccaaa cgcagtaaat
    37861 ctgggattta tctgatccaa ggggacaaca agggctgggc taacgaggaa ttggtcgata
    37921 acgaaaacgg aaactacgac tacctcatgt atgccgacct agactttaaa catcctgaag
    37981 tcatccaaaa catctatgac tgggctgatt ggttcatgga aacgactggt gtagctggtt
    38041 tccgtttgga tgccgttaag catattgact ctttctttat gcgcaacttc atccgcgata
    38101 tgaaggaaaa atacggtgac gatttctatg tttttggtga attttggaac ccagacaagg
    38161 aagccaatct ggactatctc gaaaaaacgg aagaacactt tgaccttgtc gatgttcgtc
    38221 tccaccagaa tctctttgaa gccagtcaag ctggcgcaaa ctatgacctt cgtggcattt
    38281 tcacagatag cctggttgaa ctcaagcctg acaaggctgt gacttttgtc gacaaccacg
    38341 atacccaacg aggacaagcc cttgagtcta ccgttgaaga atggttcaag ccagcagcct
    38401 atgccctcat tttgttacgc caagacggcc ttccatgtgt cttttacgga gactactatg
    38461 ggatttcagg gcagtatgct caacaagatt tcaaagaaat ccttgaccgc ctcctagcca
    38521 tccgaaaaga tttggcctat ggagaacaaa atgactactt tgaccatgct aactgtatcg
    38581 gttgggtacg ttcaggtgct gaaaatcaat ccccaatcgc agtccttatc tcaaatgacc
    38641 aagaaaacag caagtcaatg tttgtcggtc aagaatggac taatcaaacc tttgtagatt
    38701 tacttggtaa ccaccaaggt caagttacaa ttgatgagga aggttatgga caattccctg
    38761 tctcagctag atccgtaagt gtctgggcag tcaataccat ctaatagctc ataataacca
    38821 agctaggtcc aagcggattt ggcttttttg tattcacaaa aagacctacc caaatggata
    38881 gatctttact tgattacaat ttacctgcta ctgcatccaa caattcttgg atcttagctt
    38941 ggttgcttcc tcctgccatg gccatgtctg gtttaccacc accacgtcca tcgatgattg
    39001 gtgctaattc tttgacaagg tttcctgcat gaaggtcttt tgtcttgctt gctacaagga
    39061 cattgacttt gtcaccgata gcagcaacta ggacaagaag atcagagtag tctttttgtt
    39121 tccagttatc tgcaaaggta cgaagggcac cggcatctga tacagacact tgactagcaa
    39181 tgtagcggtg accgttgact tccttcacat ccttgaagat atcgcctgcg gctgcagctg
    39241 cggctttttc tttcaactca gcattttctt tttgaagttg acgaagttgt tcttgaagtc
    39301 cttctacctt gtgaggtact tccttgactt gaggtgcttt caaggttgct gcaacagctt
    39361 taagagcgtc ctcttgttca cgataggctt caaaggcttc cttaccagtc actgccaaga
    39421 tacgacgagt tcctgaaccg attccttctt ctttgacaat tttgaagaga ccaatctcag
    39481 aagtgttgcc aacgtgggta ccaccacaaa gttcaataga gtagtcaccg atagtcacga
    39541 cacgaacttc cttgccgtat ttctcaccaa agagggccat cgctcccatt tctttagcag
    39601 tgtcaatatc cgtttcaact gtcttaactt caagagcttc ccagattttt tcgttgactt
    39661 gctgttcaat cgcacgaagt tcctcagcag ttactgcttg gaagtgggta aagtcaaagc
    39721 gaaggaattc aacttcgtta agagatcctg cctgtgttgc gtggtttcca aggatattgt
    39781 gaagggcagc gtgaagcaaa tgagtcgcag tgtggttttt catgacacgg tgacggcgat
    39841 tgctatcaat tgccaaggta tattcttggt tcaaggcaag cggtgcaagg acttcaactg
    39901 tatgaagggc ttgaccattt ggggctttct gaacattggt cacagtagcc acaaccttac
    39961 ctgactcatc caagatttgt ccgtagtcag ctacctgtcc acccatttca gcataaaatg
    40021 acgtttccgc aaagataaga gaggcagttc cttctgaaac agcttctact tctgcattgt
    40081 ccgccacgat agctaccaat ttagaagaca attggctagc attgtagttg aagacacttt
    40141 ctacagtgat gttttgaaga gtttcatttt gcatacccat tgagccaccc ttgacagctg
    40201 aggcacgcgc gcgttcttgc tgttctttca tggctgcttc aaaaccttca cggtctacag
    40261 tcataccagc ttcttcagcg atttcttcag tcaattcaac tgggaaccca taagtatcat
    40321 agagtttgaa gacatctgaa ccagcgataa cagattgacc tttttctttc aagtctgcta
    40381 caatgccttg ggcaaagtgt tgacctgagt gaagggtacg ggcaaatgat tcttcttcgc
    40441 tcttaacgat tttctcaata aagtcacgtt tctcaagcac ttctgggtag tagctttcca
    40501 tgatttttcc aacagttgga accaatttgt aaaggaaagg ctcgttgata cccaattttt
    40561 gaccatgcat agaagcacga cggagaagac gacgaagaac ataaccacga ccttcatttc
    40621 ctggaagggc accatcaccg atagcaaatg aaagagaacg aatgtggtct gcgataacct
    40681 tgaagctcat gttgtcgcca tcttggtcat aaaccttacc agacaatttc tcgacttcac
    40741 ggataatcgg catgaagagg tccgtttcaa agttggtctt agccccttgg ataacggcca
    40801 ccaaacgctc caaaccagcg cccgtatcaa tgttcttatg tggcaattcc ttgtattcgc
    40861 tacgaggaac agcagggtct gcgttaaatt gtgacaaaac gatgttccag atttcaatat
    40921 aacggtcgtt ttcaatatct tctgcaagca ggcgaagacc gatattttct gggtcaaagg
    40981 cttccccacg gtcaaagaag atttctgtat ctggtccaga aggtcccgca ccgatttccc
    41041 agaagttgtc ctcaattgga atcaagtgac ttggatccac tcccacttca atccagcggt
    41101 tgtaagaatc tttatcgtct ggatagtagg tcatgtaaag tttttcagca gggaaatcaa
    41161 accattcagg gcttgtcaaa agctcataag cccaagtgat agcttcgtca cggaagtaat
    41221 ccccgataga gaagttcccc agcatttcaa acatggtatg gtgacgcgcg gtcttcccta
    41281 cgttttcgat gtcgttggta cggatagcct tttgggcatt ggtaatacat ggattttcag
    41341 ggataatggt cccgtcaaag tatttcttaa gggttgctac cccagagttg atccacaaaa
    41401 gagttgggtc atttacagga accaaactta ctgatggttc tactgagtga cctttggtcg
    41461 cccagaaatc aagccacatt tggcgtactt gtgcactaga tagttgtttc atattgtctc
    41521 cttattcact tgtttaatgt gattggcttt ccagcatttc cacatagtca atcgcgacac
    41581 agagggaaat gactaggtct gcataagcgt cttcaagaac cgttacggta taggtagagg
    41641 tcagatggaa gagttccttc ttaatttccg caatcaactg atcgcgatca tccagcaatt
    41701 tgaaattcaa atcccagata ttgccctcga tacgaagacc tagattatca aactcatact
    41761 tatctcgcca gaaggtcaac ttcttacgaa tgacaaaact cgagccatcc cgaagctgaa
    41821 tctcaaaacg aggaagcaag gtcaagattt ctttactaat ctcactgact tgttcaccag
    41881 ccgcatcata gatggtaaag gttttaggaa tcttaaaaaa tgatccctcc acctgatagg
    41941 caatttctcc cctgtcattc ttgatagcga agcgttcgcc tccaagacga aacttttgtt
    42001 tgacaagaaa tgttttcatc aacacctcca aaaatcaaaa gacaagctca tatcacgaag
    42061 ggcgaaaaac cgcggtacca ccttcattca atgaacttgt cattctcttg ttcttatgca
    42121 attgtatgat tgagtagcat gacttcctag cttagatggc tcgcagcacc gccatttctc
    42181 tggactaaga caagtgaaaa tcaattctca actttcttat tatatcgttt ttttaatctt
    42241 gcgtcaactg gaaatgatct ccgttgaatt agaccaattc cctacatctc tgattacttt
    42301 ttcaggatat attttttctt actgccattt ttctttttat cccaaatttt catattacta
    42361 aacacagcta ctagaatatt tccaaatata aaggtgccta tcacccaata tatggactca
    42421 gttgttaggt attgtcgatc caagccatcc tttaaatgga atagtataac agtttggtta
    42481 acaatcataa aggttggcca gaaacttttt ttgaaaaaag tagacatttt cattatttgt
    42541 tgccgctttc tgtaaggtta atactcaata aaaatcaaaa agcaaactag gaagctagcc
    42601 tcaagctgta cttgagtacg gcaaggcaac gctgacgtgg tttgaagagt ataggcttag
    42661 tatactacta ggcaagcaaa taagcaaata aacaaataaa caactagaat agaaaaagat
    42721 agggctctaa aaactgactt ctattcctta aaaacgaacc agcttgactg attcgtcttc
    42781 ttacgtttat ctcctacttc cgatacattt taaactgtag gaagaggtcg ctatatttcc
    42841 ctgtccattt atggtcaaat ttctcataaa cttctaggtg tttcatggtt tcaacatcgg
    42901 gatagaaggc cttatcttcc tttgtttcct ctgggagcaa ttccttcgct ggtaggtttg
    42961 gtgttgaata gccgacatac tccgcatttt ggagagcatt ttcaggtttc aacataaagt
    43021 tgataaaggc ataggctgag ttttggtttt taactgtttt gggaatgacc atattgtcaa
    43081 accaaagatt gctggcctct gtcggtacca cataacgtag attttcattt ttttctaaca
    43141 tttggctggc ttcaccagag aaggtcacgc cgattgcaac attattctga atcatatagc
    43201 ccttcatctc gtccgcaacg atagccttga tatttggagt cagtttgtag agcttatcca
    43261 ctgtctcttc caactgctgc agatccttgg agttgaggct gtagccgagg gaattgagtc
    43321 ctagtcccag cacctcacgc gccccatcaa agagcatgat agaattctta tactccggct
    43381 tccaaaggtc atcccaatgc tcaggcgctt catctaccat ggtttcgttg tagacaattc
    43441 ctaaggttcc ccagaagtaa gggatggaga atttattacc tgggtcaaag gactggttga
    43501 gaaactctgg tccgatattt tcgattcctt taatttttga ataatcaagc ggaaccaaga
    43561 ggtcttcgtc cttcatcttg ttaatcatgt attcacttgg aatggcaata tcgtaggtcg
    43621 ttccaccctg ctttatctta gtgtacatgg cttcgttgga gtcaaaagtc tcgtactgaa
    43681 cttgaattcc tgtttcttct gtaaactgag tcaagagttc aggatcgata tagtctcccc
    43741 agttatagat aaccaatttt tgactatctc gactattgat tttactatct aaatgagtcg
    43801 caattcccca caagacaagg ataatcgctg caattcctgc taaaaatgaa tagatttttt
    43861 tcatgcttgc tcctccttct cacgagagat aaagtaataa cctacaacta ggataatact
    43921 aaagagaaag actagagcag acagggcatt gatttctaag gaaatcccct tgcgagcacg
    43981 agagtaaatc tcgactgata gggttgaaaa gccatttcct gttacaaaga aggtcacggc
    44041 aaaatcatcc agcgaatagg tgaaggccat gaagtaacct gcaatgatag acggagtcag
    44101 gtaaggaagc atgatttcct taaacatctg aaattgacta gctcccaagt cataggccgc
    44161 atgaatcatg tcgccattca tttccttgag tcgaggcaag accatcaaga ccacgatagg
    44221 aatggagaag gccacgtgac tagatagaac ggtcaaaaag ccaagtgaaa acttgagttg
    44281 ggtaaagaga atcaagaagc tagcaccaat cataacgtca ggcgcaacca tgaggatatt
    44341 attgagtgat agaaaggctt cttggtattt cttacgagac tggtagatgt aaatggcacc
    44401 aaaagtcccg ataatggtcg ctatcaaggc tgataggaag gccaagaaaa atgtctgagc
    44461 caaaatcagc atgagtctcc catctccaaa catggtttca aagtgagtcc agctaaaacc
    44521 tgtaaagcta ttcatatcat caccagcatt aaaggcatag ccaatcaagt aaaaaatcgg
    44581 caggtagagg accagaaaga ccagtcccag ataaaggttg gcaaattttt tcatcgttct
    44641 ctcctttcct tggtcaccca catggtgatg aacatggtca ggatgagaat cacaccgatg
    44701 gttgaaccca taccatagtt gtcattggtt agaaaattct gctcaatagc cgtccccaag
    44761 gtgataacgc ggttcccacc aatcaaacgg gtcagcatga agagactcaa acttgggata
    44821 aagaccgact gaaccccact tcgcacaccg ttcatagata gagggaagat gacatgacgg
    44881 aaggtctccc acttagttgc accaaggtcg taactagcat tgatgagatt attatccata
    44941 tcgtctaaga cattgaaaat cggcaaaatc ataaagggga gctcgatgta gcttgcgaca
    45001 aagataaagg aaaaatcggt aaaaagcaac tgttgtgaac caattccgat aaattccaag
    45061 aattggttaa tagagccatt ttgaccaaaa atcccgataa aagcataggc tttaaggagc
    45121 aaattgatcc aggtaggaag gataatcagc atgagccaga gttgacggtg cttgagacgg
    45181 gtcaaaaaga gggctgttgg atagctgata agcaaggtca caaaggtcac aatccctgca
    45241 taaagcactg agttgaaact cattttgagg taggtcaagt tttgtgacgc aaagtaagat
    45301 ttataatttt ctaaactaaa ctggccttca atgttgaaaa aggattgtcc gaaaatcaag
    45361 accaagggtg ccaatacaaa gagggcaatc caaagcatgt agggcactac aaagagttta
    45421 gagcttgttt tcttcatctc tttcctcctc gatcgcattg atcagacctg cttcttgctc
    45481 ttcgatttcc acgtattctt cgatacgagc atcgaactct tcttcggttt cattgagacg
    45541 catgatgtgg atgtcttctg attcaaagtc cagaccgatt tcctcaccca cgatggcctt
    45601 acgggttgag tggatcatcc attcatttcc aagttcgtca taggcgataa tttcataatg
    45661 aactccacgg aagagctggg tgtcgacctt aacttggagt ttgccttctt caggaagggt
    45721 aatgcgcaag tcctctggac gaataacgac ctcaacaggt tcatttggct tcatcccacc
    45781 atcaaccgct tcaaagcgtt tgccgttaaa ttcgaccaag tagtcctcaa tcatggtacc
    45841 tggcaagatg tttgactccc cgataaaggt ggcaacaaag tggttgattg gctcatcgta
    45901 gatgtccaca ggggttccag actggacaat ctcgccatca ttcataacga aaatccagtc
    45961 actcatggca agagcttctt cctgatcgtg agtgacaaag acaaaggtaa tgcccaatcg
    46021 ttgttgtaat tcacgcaatt cgtactgcat gtctgttctc aatttcaagt ccagcgctga
    46081 taaaggctcg tccaacaaga ccacacgggg ttggttgatg atagcacggg cgatggccac
    46141 acgctgacgt tgtcctccag aaagtttgcg gatggaacgt ttttcataac cttccaactg
    46201 aaccatcttg agaacttccg ctacacgctg ctcgatttct ttcttatcaa ttttacgcaa
    46261 gcgaagtgga aaggcaacat tttcaaacac attcatatgt gggaacaagg cataggattg
    46321 gaagacggta tgtacgtcgc gcttgttggt tggaatatca ttgatacgaa caccgtctag
    46381 catgatatct cctgtcgtcg catccagtaa acctgcaata atgtttagga tagttgattt
    46441 ccccgaacca gatgcaccta gaagggtgta gaatttccct tcttccaact caaagttgat
    46501 gtctttgaga accttggtgt tgctgtcttc aaaaacttta gagacgtttt tgaattcgat
    46561 aattggtttt ttcaattggc ataaattcct tctttttcat agattaaccg atcggggctc
    46621 tgtcaggtcc ccactacctc ttgcagggag taaaaccacc tgcatacatc ttcgctaccg
    46681 ataggctttc accccctttc catgacatag cagcagcttt tcaaatacag cttcctactt
    46741 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    46801 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    46861 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    46921 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    46981 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    47041 cttgataacc tgatgggttc ctggggctag ggcaaattta actgacaaga caactgcacc
    47101 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    47161 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    47221 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    47281 ctcaaagcca gtcaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    47341 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    47401 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    47461 ccaagggata ttttcttggt tggcaaattt cacaaggcgc gccaactcaa aacgatttcg
    47521 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    47581 ttccttaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    47641 gtcactcttc cttttacaaa attcattcca ttataccatt tttagagaca tttgacgacc
    47701 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    47761 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    47821 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    47881 gaaggcatgc aagccatagg ctgctaggag ataaatccat ttcttctggc gaacagcttg
    47941 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    48001 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    48061 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acgatgtaaa gattgagtaa
    48121 actaataagg cctagaaaaa tcaactccaa gccaccatgc cctaggccat aggccaaggc
    48181 atctgccttt tccaaacttc tctttttctc caaccatttg aagaaaacaa gacgagccgt
    48241 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    48301 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    48361 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    48421 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    48481 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    48541 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    48601 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    48661 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    48721 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    48781 atattccggt tgatgggttg cgacatcagc aaacttagta tcgggtgttg acttaggaat
    48841 catacgcaca tgcatatgtg aaaattctcc ccgaatcttg atagaacgga aaagattttc
    48901 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    48961 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    49021 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    49081 caagacaatc aattccccat caatagaatc caaggttccc aaaccaaggt caccatgctc
    49141 tagcaattct cccactgtca tggtaccacc ataaaggcca gccatcaagg ctccaagagt
    49201 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    49261 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    49321 acgctctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    49381 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    49441 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    49501 tttcactgta gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    49561 ctctatgcca agccccagag tggctactat gtcctagaac aagggcaaca ccaggaccta
    49621 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    49681 gaaaccttga ttggccgaga aaactacctc ttcaactact atgataatca agaaggatta
    49741 gaagacctaa gacaatccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    49801 aaccaactag tactgacttc tggaacccaa caagccttgt ttatcctctc tcaaatatcc
    49861 tttcctagcc aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    49921 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    49981 ctgaaggagc tggagcgaca cttcaagaca ggaaaaatta agtttttcta caccattccc
    50041 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc cattcttaac
    50101 ttagctgcca agtatgatgt ctatatcgta gaagacgatt atctgggtga tttggactcc
    50161 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    50221 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    50281 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    50341 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    50401 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    50461 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    50521 gccagtctca aacacagtca accgggcttg gacttctttg aagaggccta tttaagtacc
    50581 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    50641 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    50701 ttgctgcttt ttcaagatag ctttggtaaa ttccttcatc cttaagtttt tggatgacct
    50761 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    50821 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    50881 taagtgcaac aggctcatcc atatgaacag catctacttt tccagcctgc aattcattga
    50941 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    51001 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    51061 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    51121 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    51181 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttgagattt
    51241 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    51301 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    51361 ccacaactaa tttccccttt tgcttaattg cctcaacagc tgactgagaa ccattagaac
    51421 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    51481 tttttgattt cataaataaa caacctctct gttaattttg tataattata acgatatcca
    51541 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    51601 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    51661 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    51721 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    51781 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    51841 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    51901 ctgcttcaac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    51961 gaatacgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    52021 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    52081 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    52141 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    52201 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    52261 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    52321 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    52381 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    52441 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    52501 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    52561 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    52621 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    52681 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    52741 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    52801 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    52861 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    52921 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    52981 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aataaacgga
    53041 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    53101 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    53161 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    53221 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    53281 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    53341 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    53401 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    53461 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    53521 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    53581 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    53641 gagaatctgc ccagttactt tagcaatatc aatggtatca ttcatgcgat tgagactgcg
    53701 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    53761 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    53821 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    53881 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    53941 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    54001 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    54061 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    54121 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    54181 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    54241 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    54301 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    54361 ctgtcaaggc caaggcacct gaaatgattg aaaacccata ctcaaactgg actacaaaga
    54421 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    54481 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    54541 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    54601 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    54661 aagagatatg gggcaagccc cgaaccaaga tatagagaat taaggaagcc aagattgtca
    54721 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    54781 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    54841 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    54901 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    54961 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    55021 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    55081 acacgccaga tagtctgcca gcgagtggct cccatagcga aactggcctc acgataataa
    55141 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    55201 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    55261 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    55321 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    55381 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    55441 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    55501 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    55561 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    55621 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    55681 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    55741 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    55801 ccgagagaac aaaattgaga aattctgcag ccaactcatt gggctgcccc aatgtataca
    55861 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    55921 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    55981 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    56041 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gaaccagagc
    56101 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    56161 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    56221 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    56281 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    56341 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    56401 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    56461 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    56521 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    56581 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    56641 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    56701 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    56761 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    56821 tagatgataa tccaaaagct agaaaggtat ctcaaacctc tctactctcc cagactagtt
    56881 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    56941 ctaataacta aacttcttgt actctttgaa aatctcttca aaccagtgtt ttgagctatc
    57001 tatggctagc ttcctagttt gctctttgat tttcattgag tagtaaaact acatgtaatg
    57061 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    57121 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    57181 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    57241 aaccatttgg cagactttct gccagctgaa cgatttctcc agccgcatac ttgacaaacg
    57301 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    57361 cgaaactggg ctcaaagcgt ttcttcttaa aagtgcccag atgcagtcca ttgcgagcaa
    57421 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaag
    57481 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    57541 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    57601 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    57661 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    57721 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    57781 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    57841 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    57901 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    57961 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    58021 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    58081 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    58141 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgagct acttgagcca
    58201 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    58261 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    58321 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    58381 gaaaatctct tgcctcatct cctagtatct ctttatattt ttcaacaaat ccttctggaa
    58441 attgcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    58501 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    58561 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    58621 gataagtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    58681 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    58741 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    58801 gagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    58861 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    58921 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    58981 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    59041 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    59101 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    59161 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttactttcca
    59221 agagaaatct ttccttcccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    59281 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    59341 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    59401 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    59461 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    59521 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    59581 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    59641 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    59701 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    59761 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    59821 tatgtttttc taaccaggcc ttagccttac gacatgatgt acagctcggt gatagaaata
    59881 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    59941 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaagaaaa ataggctgtt
    60001 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    60061 atatattttt atatatgcaa attaaaaaca tctttcattt cacttcctac gacttttcag
    60121 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    60181 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    60241 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    60301 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    60361 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    60421 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcagacc
    60481 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    60541 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    60601 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    60661 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    60721 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    60781 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    60841 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    60901 agtgctcaac cgccttgtcc ataatgatgg catttggttt tccgatataa accggcttca
    60961 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccgcgtt
    61021 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    61081 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    61141 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    61201 ctccgacgac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    61261 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    61321 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    61381 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat tcggtctttc cccttataaa
    61441 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    61501 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    61561 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    61621 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    61681 atgacctcaa aaatccagtc caagtattta ctgttattga catgaccatt catatccaag
    61741 tcgtaaaaac gaacatggta atccttgctg atcggttctt ccaaggactc atacttcggt
    61801 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    61861 acatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat gtggatgagc
    61921 tcctgctccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    61981 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    62041 tcatattcta cgataatcca gaccagatta tattcttcca aaatggcctt atcactaact
    62101 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaatcac atctggaagt
    62161 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    62221 aagcccatga tcctactcca aaataaatcg ttctgctaca gtatctccca aaaagagacc
    62281 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    62341 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    62401 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    62461 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    62521 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    62581 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaaaccggg
    62641 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    62701 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    62761 ccggttcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    62821 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    62881 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcagac gatcgatatt
    62941 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    63001 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    63061 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tccaagacag acaagtccaa
    63121 gtttttagtc aagccattca gtaacacctc cagttgcgga gccgacaggg ctgtcggtgt
    63181 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    63241 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    63301 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    63361 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    63421 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    63481 gagtcatcaa gagcttcggc tttttcttgc cattgttcct tgagattatt taattgattt
    63541 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    63601 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    63661 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    63721 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    63781 aaggcaagag ctgcacctga aaccgttcct aaaaggattg aggataattt acccataagg
    63841 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    63901 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    63961 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    64021 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    64081 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    64141 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    64201 gctagggcaa caagaatata tgcaacttct aacatttatt tttcctcctc tgtaatatag
    64261 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    64321 actgacagcc attgggacac tcgaaggctg aagaacatga gactatctgt tcgcatacct
    64381 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    64441 ctgagactct tccatttccg tctaaaaatc agaatcaaag caaagccaag cagattccat
    64501 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    64561 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    64621 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    64681 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    64741 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    64801 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    64861 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    64921 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    64981 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    65041 agcaatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    65101 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    65161 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    65221 aagacgatca aaggtcttat gtgtatcgta attttccaaa tagacagcaa gctgaacctg
    65281 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    65341 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    65401 cttggcaaag atatcgacac ggtcatcggc taccaaacgg tgaccacgtt tgacaagctc
    65461 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    65521 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    65581 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    65641 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgagcaa caatgactgc
    65701 tggtgtctca ggtagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    65761 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tatagtagtc
    65821 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    65881 aagcaactct ggttcaccat agacaatgtc tagtctaagc ttttcaatca cttcttttac
    65941 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    66001 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    66061 ttctctagcc tttcatttca attagaattt tttacgttta cgagctactt ctgatttacg
    66121 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    66181 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    66241 tactactgtt ttagacattt ttttcactcc cttcaagttc aatatctatt tcattctaca
    66301 cgtaaaagga ataattgtca agcaaaaatg cggtttaatt ttgatttttt cttccattta
    66361 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    66421 cttcagcatc tgcgatgatg gttacatcag ggtgattttg aaggctactt gcaggtaggt
    66481 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    66541 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    66601 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    66661 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    66721 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    66781 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    66841 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagattgt ggattgtccc
    66901 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    66961 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    67021 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    67081 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    67141 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    67201 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca aatatatgaa
    67261 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    67321 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    67381 cttctactct attattgata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    67441 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    67501 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    67561 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    67621 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    67681 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    67741 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    67801 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    67861 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    67921 cgaaatgcac tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    67981 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    68041 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    68101 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    68161 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    68221 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgacgcca tgtttattta
    68281 ttgagaaaga atttctctaa ttcttctaat accaataaat cgctaagata ttatttcaaa
    68341 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    68401 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    68461 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    68521 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    68581 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    68641 tactcttcaa aaatctcttc aaaccgcgtc aacgtcacct tggattatat atgtgactga
    68701 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    68761 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    68821 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    68881 gctttttata tataattata tattcagaca tactattatc aattttgtcg cagggaggaa
    68941 tctgttaacg cacccattca ccattatcat tgactctata gccatctata cttgtattga
    69001 ccgctaactc acccgatgta tttacataat accatttacc accaacttgg aaccattgat
    69061 tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact tgtacccaac
    69121 ctgttgccat ggaaccatca gtattataaa aataccacat accattttct tgtttccagc
    69181 ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct tggttagatg
    69241 taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact ttttcaggtt
    69301 ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga cgagaagtag
    69361 tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga gtaatttacc
    69421 aatttctcct acttcttcta cttcttgact tttatcaaga gttgggccat cgagatattc
    69481 tgtttcgatt gaaatttctt ggacaagaac ttggggcttg gttccttttt taacaactct
    69541 tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac tctttccatc
    69601 tacatcataa gttatcgttg taactatttt cccattcttt cctagagtaa tctcttgctc
    69661 ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcaaatggaa caaaaacttc
    69721 ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttctt ttctatcaac
    69781 agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc ttgtcgtagt
    69841 tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt ttgtttcatc
    69901 tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag gtttagtcgc
    69961 tacttttaca ataatatccc cattgtcagc gtcatcatac tctattccct cttctttatc
    70021 tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac ttgtattcag
    70081 attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt tccgagttta
    70141 cgtattgcat agcgcttatt agtattagat tttgccatta catcctactt ctagtatagc
    70201 atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt agaatgatat
    70261 at
//
LOCUS       DAVKBK010000004        68701 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVKBK010000004 DAVKBK010000000
VERSION     DAVKBK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68701
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.004"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            528..1391
                     /locus_tag="VWX69_000232"
     CDS             528..1391
                     /locus_tag="VWX69_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9191642.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            1677..1877
                     /locus_tag="VWX69_000233"
     CDS             1677..1877
                     /locus_tag="VWX69_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEU9191643.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            1944..2609
                     /locus_tag="VWX69_000234"
     CDS             1944..2609
                     /locus_tag="VWX69_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9191644.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            2681..3907
                     /locus_tag="VWX69_000235"
     CDS             2681..3907
                     /locus_tag="VWX69_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9191645.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(4260..4334)
                     /locus_tag="VWX69_000236"
                     /pseudo
     CDS             complement(4260..4334)
                     /locus_tag="VWX69_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4405..5061
                     /locus_tag="VWX69_000237"
     CDS             4405..5061
                     /locus_tag="VWX69_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU9191646.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            5051..5260
                     /locus_tag="VWX69_000238"
     CDS             5051..5260
                     /locus_tag="VWX69_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU9191647.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPTIVERFLKFL
                     PVSIIFALILSRVVTGKVGNLPQIK"
     gene            5478..6308
                     /locus_tag="VWX69_000239"
     CDS             5478..6308
                     /locus_tag="VWX69_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9191648.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            6462..7316
                     /locus_tag="VWX69_000240"
     CDS             6462..7316
                     /locus_tag="VWX69_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9191649.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            7416..8789
                     /locus_tag="VWX69_000241"
     CDS             7416..8789
                     /locus_tag="VWX69_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU9191650.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYHTHIELVE
                     ELIRSYE"
     gene            8782..9843
                     /locus_tag="VWX69_000242"
     CDS             8782..9843
                     /locus_tag="VWX69_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU9191651.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            9845..10537
                     /locus_tag="VWX69_000243"
     CDS             9845..10537
                     /locus_tag="VWX69_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191652.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(10566..11135)
                     /locus_tag="VWX69_000244"
     CDS             complement(10566..11135)
                     /locus_tag="VWX69_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9191653.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            11270..11884
                     /locus_tag="VWX69_000245"
     CDS             11270..11884
                     /locus_tag="VWX69_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9191654.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            11886..13532
                     /locus_tag="VWX69_000246"
     CDS             11886..13532
                     /locus_tag="VWX69_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9191655.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            13544..14830
                     /locus_tag="VWX69_000247"
     CDS             13544..14830
                     /locus_tag="VWX69_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9191656.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            14882..15415
                     /locus_tag="VWX69_000248"
     CDS             14882..15415
                     /locus_tag="VWX69_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191657.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            15493..15963
                     /gene="nrdI"
                     /locus_tag="VWX69_000249"
     CDS             15493..15963
                     /gene="nrdI"
                     /locus_tag="VWX69_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU9191658.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(16256..17518)
                     /locus_tag="VWX69_000250"
     CDS             complement(16256..17518)
                     /locus_tag="VWX69_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU9191659.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(17828..18286)
                     /locus_tag="VWX69_000251"
     CDS             complement(17828..18286)
                     /locus_tag="VWX69_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU9191660.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(18283..18723)
                     /locus_tag="VWX69_000252"
     CDS             complement(18283..18723)
                     /locus_tag="VWX69_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9191661.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19079..21028
                     /gene="mutL"
                     /locus_tag="VWX69_000253"
     CDS             19079..21028
                     /gene="mutL"
                     /locus_tag="VWX69_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU9191662.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(21353..21820)
                     /locus_tag="VWX69_000254"
     CDS             complement(21353..21820)
                     /locus_tag="VWX69_000254"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU9191663.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(21821..23026)
                     /locus_tag="VWX69_000255"
     CDS             complement(21821..23026)
                     /locus_tag="VWX69_000255"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU9191664.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLIERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(23046..23681)
                     /gene="ribE"
                     /locus_tag="VWX69_000256"
     CDS             complement(23046..23681)
                     /gene="ribE"
                     /locus_tag="VWX69_000256"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU9191665.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(23666..24766)
                     /gene="ribD"
                     /locus_tag="VWX69_000257"
     CDS             complement(23666..24766)
                     /gene="ribD"
                     /locus_tag="VWX69_000257"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU9191666.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(24900..25014)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25171..25764
                     /gene="ruvA"
                     /locus_tag="VWX69_000258"
     CDS             25171..25764
                     /gene="ruvA"
                     /locus_tag="VWX69_000258"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU9191667.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            25774..26337
                     /locus_tag="VWX69_000259"
     CDS             25774..26337
                     /locus_tag="VWX69_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU9191668.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     VLLQLQAEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            26334..27011
                     /locus_tag="VWX69_000260"
     CDS             26334..27011
                     /locus_tag="VWX69_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9191669.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(27148..28179)
                     /locus_tag="VWX69_000261"
     CDS             complement(27148..28179)
                     /locus_tag="VWX69_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU9191670.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(28434..29117)
                     /locus_tag="VWX69_000262"
     CDS             complement(28434..29117)
                     /locus_tag="VWX69_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU9191671.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILTSMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(29129..30073)
                     /locus_tag="VWX69_000263"
     CDS             complement(29129..30073)
                     /locus_tag="VWX69_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9191672.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            30205..33036
                     /gene="uvrA"
                     /locus_tag="VWX69_000264"
     CDS             30205..33036
                     /gene="uvrA"
                     /locus_tag="VWX69_000264"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU9191673.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            33029..34090
                     /locus_tag="VWX69_000265"
     CDS             33029..34090
                     /locus_tag="VWX69_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9191674.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            34222..34620
                     /gene="spx"
                     /locus_tag="VWX69_000266"
     CDS             34222..34620
                     /gene="spx"
                     /locus_tag="VWX69_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU9191675.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            34686..35255
                     /locus_tag="VWX69_000267"
     CDS             34686..35255
                     /locus_tag="VWX69_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU9191676.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            35342..35608
                     /locus_tag="VWX69_000268"
     CDS             35342..35608
                     /locus_tag="VWX69_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU9191677.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            35612..36031
                     /gene="ruvX"
                     /locus_tag="VWX69_000269"
     CDS             35612..36031
                     /gene="ruvX"
                     /locus_tag="VWX69_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU9191678.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            36047..36352
                     /locus_tag="VWX69_000270"
     CDS             36047..36352
                     /locus_tag="VWX69_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU9191679.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            36609..37859
                     /locus_tag="VWX69_000271"
     CDS             36609..37859
                     /locus_tag="VWX69_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9191680.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            37856..38398
                     /locus_tag="VWX69_000272"
     CDS             37856..38398
                     /locus_tag="VWX69_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU9191681.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            38544..40076
                     /gene="cls"
                     /locus_tag="VWX69_000273"
     CDS             38544..40076
                     /gene="cls"
                     /locus_tag="VWX69_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU9191682.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            40334..41872
                     /locus_tag="VWX69_000274"
     CDS             40334..41872
                     /locus_tag="VWX69_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9191683.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWGLHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            41992..44199
                     /gene="nrdD"
                     /locus_tag="VWX69_000275"
     CDS             41992..44199
                     /gene="nrdD"
                     /locus_tag="VWX69_000275"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU9191684.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            44211..44351
                     /locus_tag="VWX69_000276"
     CDS             44211..44351
                     /locus_tag="VWX69_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191685.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            44395..44901
                     /locus_tag="VWX69_000277"
     CDS             44395..44901
                     /locus_tag="VWX69_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9191686.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            44894..45484
                     /gene="nrdG"
                     /locus_tag="VWX69_000278"
     CDS             44894..45484
                     /gene="nrdG"
                     /locus_tag="VWX69_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU9191687.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            45492..46109
                     /locus_tag="VWX69_000279"
     CDS             45492..46109
                     /locus_tag="VWX69_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU9191688.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            46375..46683
                     /gene="rpsJ"
                     /locus_tag="VWX69_000280"
     CDS             46375..46683
                     /gene="rpsJ"
                     /locus_tag="VWX69_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU9191689.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            46900..47526
                     /gene="rplC"
                     /locus_tag="VWX69_000281"
     CDS             46900..47526
                     /gene="rplC"
                     /locus_tag="VWX69_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU9191690.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            47551..48174
                     /gene="rplD"
                     /locus_tag="VWX69_000282"
     CDS             47551..48174
                     /gene="rplD"
                     /locus_tag="VWX69_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU9191691.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            48174..48470
                     /locus_tag="VWX69_000283"
     CDS             48174..48470
                     /locus_tag="VWX69_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU9191692.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            48488..49321
                     /gene="rplB"
                     /locus_tag="VWX69_000284"
     CDS             48488..49321
                     /gene="rplB"
                     /locus_tag="VWX69_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU9191693.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            49425..49706
                     /gene="rpsS"
                     /locus_tag="VWX69_000285"
     CDS             49425..49706
                     /gene="rpsS"
                     /locus_tag="VWX69_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU9191694.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            49718..50062
                     /gene="rplV"
                     /locus_tag="VWX69_000286"
     CDS             49718..50062
                     /gene="rplV"
                     /locus_tag="VWX69_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU9191695.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            50075..50728
                     /gene="rpsC"
                     /locus_tag="VWX69_000287"
     CDS             50075..50728
                     /gene="rpsC"
                     /locus_tag="VWX69_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU9191696.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            50732..51145
                     /gene="rplP"
                     /locus_tag="VWX69_000288"
     CDS             50732..51145
                     /gene="rplP"
                     /locus_tag="VWX69_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU9191697.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            51155..51361
                     /locus_tag="VWX69_000289"
     CDS             51155..51361
                     /locus_tag="VWX69_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU9191698.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            51386..51646
                     /gene="rpsQ"
                     /locus_tag="VWX69_000290"
     CDS             51386..51646
                     /gene="rpsQ"
                     /locus_tag="VWX69_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU9191699.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            51672..52040
                     /gene="rplN"
                     /locus_tag="VWX69_000291"
     CDS             51672..52040
                     /gene="rplN"
                     /locus_tag="VWX69_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU9191700.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            52118..52423
                     /gene="rplX"
                     /locus_tag="VWX69_000292"
     CDS             52118..52423
                     /gene="rplX"
                     /locus_tag="VWX69_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU9191701.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            52447..52989
                     /gene="rplE"
                     /locus_tag="VWX69_000293"
     CDS             52447..52989
                     /gene="rplE"
                     /locus_tag="VWX69_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU9191702.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            53007..53276
                     /gene="rpsN"
                     /locus_tag="VWX69_000294"
     CDS             53007..53276
                     /gene="rpsN"
                     /locus_tag="VWX69_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU9191703.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            53561..53959
                     /gene="rpsH"
                     /locus_tag="VWX69_000295"
     CDS             53561..53959
                     /gene="rpsH"
                     /locus_tag="VWX69_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU9191704.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            54151..54687
                     /gene="rplF"
                     /locus_tag="VWX69_000296"
     CDS             54151..54687
                     /gene="rplF"
                     /locus_tag="VWX69_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU9191705.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            54771..55127
                     /gene="rplR"
                     /locus_tag="VWX69_000297"
     CDS             54771..55127
                     /gene="rplR"
                     /locus_tag="VWX69_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU9191706.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            55145..55639
                     /gene="rpsE"
                     /locus_tag="VWX69_000298"
     CDS             55145..55639
                     /gene="rpsE"
                     /locus_tag="VWX69_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU9191707.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            55611..55835
                     /gene="rpmD"
                     /locus_tag="VWX69_000299"
     CDS             55611..55835
                     /gene="rpmD"
                     /locus_tag="VWX69_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU9191708.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            55980..56420
                     /gene="rplO"
                     /locus_tag="VWX69_000300"
     CDS             55980..56420
                     /gene="rplO"
                     /locus_tag="VWX69_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU9191709.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            56433..57743
                     /gene="secY"
                     /locus_tag="VWX69_000301"
     CDS             56433..57743
                     /gene="secY"
                     /locus_tag="VWX69_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU9191710.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            57894..58532
                     /locus_tag="VWX69_000302"
     CDS             57894..58532
                     /locus_tag="VWX69_000302"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU9191711.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            58649..58867
                     /gene="infA"
                     /locus_tag="VWX69_000303"
     CDS             58649..58867
                     /gene="infA"
                     /locus_tag="VWX69_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU9191712.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            58892..59008
                     /gene="rpmJ"
                     /locus_tag="VWX69_000304"
     CDS             58892..59008
                     /gene="rpmJ"
                     /locus_tag="VWX69_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU9191713.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            59026..59391
                     /gene="rpsM"
                     /locus_tag="VWX69_000305"
     CDS             59026..59391
                     /gene="rpsM"
                     /locus_tag="VWX69_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU9191714.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            59409..59792
                     /gene="rpsK"
                     /locus_tag="VWX69_000306"
     CDS             59409..59792
                     /gene="rpsK"
                     /locus_tag="VWX69_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU9191715.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            59835..60770
                     /locus_tag="VWX69_000307"
     CDS             59835..60770
                     /locus_tag="VWX69_000307"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU9191716.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            60782..61168
                     /gene="rplQ"
                     /locus_tag="VWX69_000308"
     CDS             60782..61168
                     /gene="rplQ"
                     /locus_tag="VWX69_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU9191717.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            61433..61699
                     /locus_tag="VWX69_000309"
     CDS             61433..61699
                     /locus_tag="VWX69_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU9191718.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            61709..63046
                     /locus_tag="VWX69_000310"
     CDS             61709..63046
                     /locus_tag="VWX69_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU9191719.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            63290..63982
                     /locus_tag="VWX69_000311"
     CDS             63290..63982
                     /locus_tag="VWX69_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9191720.1"
                     /translation="MVKVRLYLIRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(64085..65721)
                     /locus_tag="VWX69_000312"
                     /pseudo
     CDS             complement(64085..65721)
                     /locus_tag="VWX69_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(65711..66739)
                     /locus_tag="VWX69_000313"
     CDS             complement(65711..66739)
                     /locus_tag="VWX69_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191721.1"
                     /translation="MNITIPKGSLFTLLGPSGCGKTTLLRMIAGFNSIKDGEFYFDDT
                     KINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLKQKKVPKEELIQQTNKYLELMQI
                     AQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEPLSNLEAKLRLDMRQAIREIQH
                     EVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNI
                     IPANLEKRSDGAYIVFSDGYALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISD
                     SVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKDNRIRLRINTQKLNIFSADGSQNL
                     IKGVNHGM"
     gene            complement(66814..67920)
                     /locus_tag="VWX69_000314"
                     /pseudo
     CDS             complement(66814..67920)
                     /locus_tag="VWX69_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(68152..68349)
                     /locus_tag="VWX69_000315"
     CDS             complement(68152..68349)
                     /locus_tag="VWX69_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9191722.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(68424..>68701)
                     /locus_tag="VWX69_000316"
     CDS             complement(68424..>68701)
                     /locus_tag="VWX69_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU9191723.1"
                     /translation="HYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQL
                     LPFHQFGENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
BASE COUNT        20527 a        12829 c        15021 g        20324 t
ORIGIN      
        1 aacgtaattt ttgaaaagaa ttttgaacta tttacaaaac aaagtgatct aattgttgca
       61 aatagatggg ataggggcct tgaagcttat aaagataaag tttacacaag ggggatctgg
      121 ataagagatt aactattgat attaaaaagg caataattta taaaatttgt acaaaaaaat
      181 gttaaatttt cacattttca tagtatactg tttaatagaa agtaggttct ttgtaaccgc
      241 tccattataa aatcctttca ctcttccggt atactattag gaaaaacata actggaggat
      301 attttgagct cacacctcat cgttccagtg gctgttcccc aagctcgtgt actgcccaaa
      361 aaagttagac attctattta gaacgaggat tgagttctgt attgtacaag gctcggtcct
      421 tttagagtca gcttaaggct ggctttttta ttttttctaa ctatcagaat attttgacaa
      481 atgaacacaa ataatgatat aatatgcaaa agctaggagg tggtaggatg attgaaaaaa
      541 tggaattggg ggaattttac aaggaattac gtttggcgag aaagctcaag cagtcagatg
      601 tggcttgtga cgggctaaca gcttctcagt tgtccaagtt tgagctaggg cagtccatgt
      661 tgtctgctga taagctcata ttagccatcc aagggatcaa tgtgaccttt gatgagtttg
      721 ggcacaagct caacaactat caagaatctc cacatatgca gattggtaga aaggttgtgg
      781 atcgctttgc tcatcaagat atagctggct tagagcaact gttggaggaa gtcgagcaag
      841 aacagatggc agagacttat cgtcgtttga atgctattgt aatcaaagat gccatccact
      901 cactagataa aagctaccca ctagcagagg aggatagcga gtttttgacc acctatctct
      961 atgctatcga gtcttggacc tggtttgaac tctatctctt ttgcaatact ctgcccttct
     1021 tgagcaatca agatctgatc tttttatcaa cctccttact cgaaaaatcc aaagaattta
     1081 aagagttagt acacaatcga ttgtatatga agcaaggact cttaaatatc atctcagagc
     1141 tcatggagcg caaacttttt tcttatatcc caatctttga agccgagctg gagagtatgc
     1201 tccgtccata cgatgttttt gagaaagtgt tgtggcagtt tttaaagaag atgagcattt
     1261 tccttcaaac taagggaagc aatcaaaaag agattgaaca ctttatccaa tctctgcaag
     1321 tattagaaaa tccacaatta atagcccttt ttgaattgcg tttgcagcaa tacaaaaagc
     1381 ttatcgatta gttagaaatg gcaaaataat aataatctca gcaacgattt tcaataatgt
     1441 taaaatttgt ttcttcatat ttctccactc ctcattagta gtaactttat tataccagag
     1501 aagtaatcaa attcaccaaa atcgcaaatc tgaaatttct ataagaaaaa atatcaaata
     1561 tgcgattttc taaaataagc caattttcgt gttatactgt acttgtaaag cacttgaagc
     1621 aaatcctagg tcgcagaagt ggtttacaaa tgaagataat tgaaggagtg taaaagatgt
     1681 taaatttaca atttgcagaa acaatggaat tgacagaagc tgagttggag atagtttatg
     1741 gaggggaatt tgggaataat gctgttatcc cagccggtgc ttggggaggg ttcgggacac
     1801 cttggtcaat cactaatttc tggaagaaaa attttaacga tagacctgac tttgattctg
     1861 accgccgtcg ttattaatat ccaaagccct tgccttttct tgggtagggg ctgtctttat
     1921 ttcatagtat aggaggaaat agaatgaaaa agataatctc acaccgctac tttattatag
     1981 tttttctact agttattgct gaccagaagt tcagtgttct agttttacgc agcgaccttg
     2041 ttactgggct atctgacttt gcctattatc tgtcggatat gatgttgaat tttcttgtgg
     2101 ttttatttgc tcttattgct atgatttggt cggggaaatg gcagaaaatc aatagtagaa
     2161 agtttaaagg atcctatctt ttctattcct tcctagctct gcttgctttt gttgtttgga
     2221 atttcgttac cttttttctt ttcccaccta ctcgaaatga aatttcttat caacatgctg
     2281 ctccgacttt tacaggggct acagcatttt tgatgtattt tttctatcct gtgattgcag
     2341 gtcccatttt tgaagagata atccatcggg gattggtgat gacagctctg gaaaaaggaa
     2401 agaaatgggg gctagatgta cttggctctg ctattttatt tggggtctcg cacattagta
     2461 atcacggttg ggtcttgaca gactttgtct tctatatggg tggaggtctt atatttgcag
     2521 tcttatttag aatgacaaag tcaatttatt ggcctattgg actgcatata gtctacaatg
     2581 gtattggtca gcttttgatg ttactgtaat tttggttgtt agtagtatcg cggtctattc
     2641 ttggggaaag attcccattt gaacttaaga aggagttgta atgaaagtat ttcttcaaaa
     2701 tagagatttt aggcaattaa ctatcaacca gtggatttca acgcttgggg atacgatttt
     2761 ttatctggcc ttcctgaatt atgtggcaga tgcgtctttt gcccctttgg cgattttact
     2821 tatcacgatt tcagaaaccc ttccccaagt tctacaaatc tttctgggag ttttggcgga
     2881 ttttcaacat catcgtgtct tgaaatacac agtcattagt tttacaaaat ttttgcttta
     2941 ctctatagtg tccctatcgc tttcagggca gtctttttcc ttgttgctag taacctttat
     3001 ttgtatgatt aacctcttgt ctgacacatt gagttatttt tcaggcgcca tgctcactcc
     3061 gattttcatt agaattattg ggcaagatca tctggcagaa gctattggat ttaaacagtc
     3121 aactgttagt ttagtgaaaa caatcagtaa tatcctagga ggagtcttac taggtattct
     3181 atccatccag tttatttcct tactgaacgc tcttaccttt ttaatcgcat ttttaggtat
     3241 cctcttcata aaaactgacc tcttgaaagt agaaaaaacg attagctatc aagaaggact
     3301 ctctgtaaaa tccttttgcc agcatttgct ccaatcatcg aaattgatat ggaatatgaa
     3361 taaggtgctc ttggttttgt ttattatctc tactagtcaa gcagtgataa atgttacagt
     3421 tcctgtctct actctatttt tgaggaatca accctttttg aatttacaaa caggtcaatc
     3481 tcttgccttg ctatccactt ttgaactgtc agccctgatt gtcggaagcc ttgtaagtgg
     3541 ctatctgcaa cataccattt ccataaaaac agctctctat gcctcacttg tcatccagtt
     3601 gcttcttcta gtaggatttg ccacagttcg ttttgactgg attctcatct ttagtacctt
     3661 ggatgccttt ttcgcaggtg ttctctctcc tagattgcaa gaactcgtct ttaaacaaat
     3721 acctgaggag tcaatgggag cagttcaatc ttctatcagt gccattacgg ttgttttacc
     3781 tagcttattt acaatatctt tggtaaccat tgctactagc tttggaactc tggcagttag
     3841 ctttgtttta ttgctatttc ttctagttgc ctttgttatg cttctgaata ttcgtgaaag
     3901 tatttagtgg agaatttcta taatatatgt ttgagactgg attgccagtc tttttatgat
     3961 ggtcaaaatc aacagacttt ttctcttttc tgaatgtgtt atagtagact gaatctaaaa
     4021 tagtacgaaa caattgctaa aacatttata gaaattaatt ttactttccc aatcgatttg
     4081 ttctcatctt atttcaatct gctatataat agtccatgct gtggctggat tcttttcagc
     4141 ctacttatac tcttcgaaac tctcttcaaa ccacgtcagc ttcaccttgc cgtatatgtg
     4201 ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagct gacttcatca
     4261 gttctatctg caacctcaaa acagtgtttt gagcaacctg cggctagttt cctagtttgc
     4321 tctttgattt tcattgagta ttattaagac aatatgagga gaaagatgaa agaaaaagga
     4381 ttttaggagg gggcgcaggc agccatgcca acggctcttg gctatgtcag tatcggcctg
     4441 gcctgtggaa ttatcggtgc gccctatgtg acacctgttg agatgggctt gatgagtctc
     4501 tttgtttatg ctgggagtgc ccagtttgcc atgttggcac tgattgtggt tcaagctcct
     4561 gtggcagcta ttgctatgac ggtttttcta atcaatttgc gtctcttttt gttgagctta
     4621 cacgcatcga cttatttccg tcataccagt ctttggcaca atatcggtat gtctagtatc
     4681 ttgacagatg agacctatgg cgttttgatg ggcgaattag cccatacaga taaggtcaat
     4741 ccgatgtgga tgcacgggaa caatctcaac agctatgtgg cttggtttgt gggaacagtg
     4801 gtcggaacgg ctctaggtga cctgttgcca aatccagaaa tctttggttt agattttgcc
     4861 ctggttggga tgtttatcgg gatttttgct tcgcaattcc agatgatgca aagacggatt
     4921 tctgtccgca atctgctcat tatcttagca gttgttgcag tgtccttctt tttacttttg
     4981 acagtggtgt ctcagtcact agctgttctg tttgcgacgc tacttggttg tagcatgggg
     5041 atggttttag atggtcagta agtatctttt attagcagtt attttctctg gtcttgtgac
     5101 ctggattccc cgtatgattc ccttcatctt ggtcaagtat aagggcctgc ctacgattgt
     5161 tgagcgtttt ttgaagtttt tgcctgtttc cattatcttt gccttgattc tttcaagagt
     5221 agtgacaggt aaggttggga accttcctca aatcaaatga ctggacttct tagcagtctt
     5281 tccaacagct tgggtagctt ttcgctaccg caatctagtc ggtacggttc tctttggagt
     5341 agtcttgatt gccgtcttgc gtttggtctt ttaaataagt cataaagaaa acttatcaca
     5401 gagatagata tcatataatg gcgtaattac tttttttctg ataagattat aaggtattct
     5461 attttggagg aaatgacatg aaaaaaatcg ttaaatactc atctcttgca gcccttgctc
     5521 ttgttgctgc aggtgtgctt gcggcttgct caggtggtgc taagaaagaa ggacaagcag
     5581 ctagcaagaa agaaatcatc gttgcaacca atggatcacc aaggccattt atctatgaag
     5641 aaaatggcga attgactggt tacgagattg aagtcgttcg cgctatcttt aaagattctg
     5701 acaaatatga tgtcaagttt gaaaagacag aatggtcagg tgtctttgct ggtcttgacg
     5761 ctgaccgtta caatatggct gtcaacaatc ttagctacac taaagaacgt gcggagaaat
     5821 acctctatgc cgcaccaatt gcccaaaatc ctaatgtcct tgtcgtgaag aaagatgact
     5881 ctagtatcaa gtctctcgat gatatcggtg gaaaatcgac ggaagtcgtt caagccacta
     5941 catcagctaa gcagttagaa gcatacaacg ctgaacacac ggacaaccca actatcctta
     6001 actatactaa ggcagatttc caacaaatca tggtacgttt gagcgatgga caatttgact
     6061 ataagatttt tgataaaatc ggtgttgaaa cagtgatcaa gaaccaaggt ttggacaact
     6121 tgaaagttat cgaacttcca agcgaccaac aaccgtacgt ttacccactt cttgctcagg
     6181 gtcaagatga gttgaaatcg tttgtagaca aacgcatcaa agaactttat aaagatggaa
     6241 ctcttgaaaa attgtctaaa caattcttcg gagacactta tctaccggca gaagctgata
     6301 ttaaataatt tcttgaaatc atccattctg agtaagatgg gtggtttctc agtttttagg
     6361 gatatagttt taaactatat atctgactat ctaataacaa tttgtgaaat caaacaaatt
     6421 gtgagatact agtacggtat tatttttaag gagaaagaat catgaaaatc aaaaaatggc
     6481 ttggtctagc agcccttgct acagtcgcag gtttggctct tgcagcttgc ggaaactcag
     6541 aaaagaaagc agacaatgca acaactatca aaatcgcaac tgttaaccgt agcggttctg
     6601 aagaaaaacg ttgggacaaa atccaagaat tggttaaaaa agacggaatt accttggaat
     6661 ttacagagtt cacagactac tcacaaccaa acaaagcaac tgctgatggc gaagtagatt
     6721 tgaacgcttt ccaacactat aacttcttga ataactggaa caaagaaaac ggaaaagatc
     6781 ttgtagcgat tgcagatact tacatctctc caatccgcct ttactcaggt ttgaatggaa
     6841 gtgccaacaa gtacactaaa gtagaagaca tcccagcaaa cggagaaatc gctgtaccaa
     6901 atgacgctac aaacgaaagc cgtgcgcttt acttgcttca atcagctggc ttgattaaat
     6961 tggatgtttc tggaactgct cttgcaacag ttgccaacat caaagaaaat ccaaagaact
     7021 tgaaaatcac tgaattggac gctagccaaa cagctcgttc attgtcatca gttgacgctg
     7081 ccgttgtaaa caataccttc gttacagaag caaaattgga ctacaagaaa gcacttttca
     7141 aagaacaagc tgatgaaaac tcaaaacaat ggtacaacat cattgttgcg aaaaaagatt
     7201 gggaaacatc acctaaggct gatgctatca agaaagtaat cgcagcttac cacacagatg
     7261 acgtgaaaaa agttatcgaa gaatcatcag atggtttgga tcaaccagtt tggtaataag
     7321 aaacagggag gtgggagaga aaattccacc tcttgctttt gtatagagta tagattgtaa
     7381 agaagactat tcgttcatag aaaggtagag agaatatggt ttttcctagc gaacaagaac
     7441 agattgaaaa atttgaaaag gatcatgtag tccaacatta ttttgaggtt ttgcgtacct
     7501 tgatttctaa gaaatcagtc tttgcccagc aggttggact caaggaagtc gcaaattatc
     7561 tgggtgagat tttcaagcgt gttggagctg aagtggagat tgatgagagc tatacagcgc
     7621 cctttgtcat ggcacatttc aagagttcgc gtccagatgc caagaccttg attttctata
     7681 accactatga cactgtgcca gcggatgggg atcaggtctg gacagaggat ccttttacgc
     7741 tttcggtccg caatggcttc atgtatgggc gtggggttga tgacgacaag ggtcatatca
     7801 cagctcgctt gagtgctttg agaaaatata tgcagcacca tgatgattta cctgtcaata
     7861 tcagctttat catggaggga gcggaggaat cggcttcaac agacctagat aagtatttgg
     7921 aaaagcatgc agacaaactc cgtggggcgg atttgttggt ctgggaacaa gggaccaaaa
     7981 atgccttgga gcagctggaa atttctggtg gcaataaggg gattgtgacc tttgatgcca
     8041 aggtaaaaag cgctgatgtg gatatccact cgagttatgg tggtgttgtg gaatcagctc
     8101 cttggtatct cctccaagcc ttacagtctc ttcgtgctgc ggatggccgt atcttggttg
     8161 aaggcttgta cgaagaagta caagagccca atgaacgaga aatggccttg ctagaaactt
     8221 atggtcaacg aaacccagag gaagttagtc ggatttatgg attggagttg cctctcttac
     8281 aggaggagcg gatggccttt ctaaaacgtt tctttttcga gccagcgctt aatatcgaag
     8341 gaatccagtc tggttatcaa ggtcagggtg ttaagactat tttacctgca gaagccagtg
     8401 ccaagctaga ggttcgtctg gttccgggcc tagaaccgca tgatgttctg gaaaaaattc
     8461 ggaaacagct agacaaaaat ggctttgata aggtagaatt atactatacc ttgggagaga
     8521 tgagctatcg aagcgatatg agcgcaccag ccattctcaa tgtgatcgag ttggccaaga
     8581 aattctatcc acagggcgtt tcagtcttgc cgacgacagc ggggacagga cctatgcata
     8641 cggtctttga tgccctagag gtaccaatgg ttgcattcgg tctaggaaat gccaatagcc
     8701 gagaccacgg tggagatgaa aatgtgcgaa tcgctgatta tcacacccat atcgaattag
     8761 tagaggagct gattagaagc tatgagtaga gatattatca agttagatca gatcgatgtg
     8821 acttttcacc aaaagaagag aaccattaca gcggttaagg atgtgaccat tcacatccaa
     8881 gaaggggata tctacggaat cgttggatat tctggagcag gaaaatcaac ccttgtacgg
     8941 gtgattaatc tcttgcaaaa accatctgca gggaaaatta ccattgacga cgatgtgatt
     9001 tttgacggca aggtgacctt gacggcagag cagttgcgtc gtaaacgtca agatatcgga
     9061 atgattttcc agcattttaa cctgatgagc caaaagacag cagaggagaa tgtagccttt
     9121 gcccttaaac actctgaact cagcaaggaa gaaaagaagg ctaaagtagc taagttgttg
     9181 gacttggttg gtttggcaga tcgtgctgaa aactaccctt cacaactatc tggagggcaa
     9241 aaacagcgtg tggcaattgc gcgtgccttg gccaatgatc caaaaatctt gatttcagac
     9301 gagtcaactt ctgcccttga tccgaagaca accaagcaga ttttggcctt gttgcaagat
     9361 ttgaaccaaa aattaggctt gactgttgtc ttgattacgc atgaaatgca gattgtcaaa
     9421 gacattgcca accgtgtggc ggttatgcag gatgggcatt tgattgaaga gggtagtgtg
     9481 cttgaaatct tctcagaccc taaacaacct ttgactcaag actttatctc aacagctaca
     9541 ggtattgacg aagccatggt caaaatcgag aagcaagaaa tcgtggaaca cttgtctgaa
     9601 aacagtctct tggtgcaact caagtacgct ggatcttcaa cagacgagcc acttttgaat
     9661 gaattgtaca agcattatca agtaatggct aatattctct atgggaatat cgaaatcctc
     9721 gatggtactc ctgttggaga attggtggtg gtcttgtcag gtgaaaaagc agcgttggca
     9781 ggtgcccaag aagccattcg tcaagcaggc gtacagttaa aagtattgaa gggaggacag
     9841 taagatggaa tcattgattc aaacctattt gccaaatgtc tataagatgg gttggtctgg
     9901 tcaggcaggc tggggaacag ctatctacct aaccctctat atgacagttc tttccttcat
     9961 tatcggaggc ttcttggggc tagtggcagg tctctttctc gtcttgacag cgccaggtgg
    10021 tgtcttggag aataaagtcg tattctggat tttagacaaa attacctcaa tttttcgtgc
    10081 gattcccttt atcatcctct tggcaatctt gtcaccactt tctcacttga ttgttaaaac
    10141 aagtatcggg ccaaatgcag cccttgtccc actttctttt gcagtctttg ccttctttgc
    10201 ccgtcaggtg caggttgtct tggctgaatt ggatggcggt gtcattgagg cggctcaagc
    10261 gagcggagcg actttctggg acatcgtggg tgtttaccta tcagaaggtc ttccagattt
    10321 gatccgtgtg acgactgtga ccttgatttc ccttgttggg gaaacagcta tggccggtgc
    10381 ggttggagct ggtggtatcg gtaacgtagc catcgcttat ggatttaacc gctacaatca
    10441 cgatgtgacc atcttggcaa ccattattat cattttgatt atctttgcaa tccaattctt
    10501 gggagatttc ttgactaaga aattgagtca taaataaaaa gagccgcgtg gctcttttta
    10561 actgatcaga ttttctgtgc aaatttttta ctcaaggctt gtccaatcaa ggcacccact
    10621 agggctccga tgacaatact tgcgataaat agaaggacag ttccagggtt tggagcgacc
    10681 atgatacggt cgatatattc ttgggatttt cctcttgcca gaagagtagc catataggct
    10741 ttgggcgcaa tccacataag caagattggt cctgttgtac taaaggcgaa aataatgaaa
    10801 gaaaggaagt tctttgtttt gtccttgtat tttcctaaat gagctacttc atctgctagg
    10861 aggccacaga taattccagg aaggaaggaa ccagcaccgt gtttagttcc caagaaaaag
    10921 agggcaatga caaggccgat agtggtaatg gctccaaagc gcggaacttt tgcgactagg
    10981 atcatataga cgctaccgcc gacaagggca gtaaaggcag gcgcataaaa catgtttcca
    11041 gtttggtcaa agagattgcc caaaaggaca ccaatcccca tgcagaggaa gtaaagaact
    11101 gcaaaaagca gtgtagttaa gatagatttc ttcatgaatt gtctcctgat aattttttca
    11161 caattctcat tgtaccacgg tttggtggga ttgtaaatgg atactagaag tttttgaaaa
    11221 cgcttgaaat atgatataat ggtttcatag ttatttttag gggaatatca tgggtagatt
    11281 tttagacttt gtctttaatc gtttcttttt agggatgatt gcgacagcct tcttttggct
    11341 attaacttta gcaggaggga ttatccttgg tctagcgccg gctagtgcca ccttgatgag
    11401 cttatatgca gaacatggtt atagctttcg ggaatacagt ttgaaggagg cttggtctct
    11461 ttacaagcaa aattttgtct caagcaacct gattttctat agctttttag gtgtgggtct
    11521 agttttgacc tatggtttgt atctcttggt gcaattgcct catcagacca ttgttcattt
    11581 gattgcgacc cttttgaatg tcctagtagt tgccctgatc tttttggctt atacagtatc
    11641 tttaaaatta caagtttatt ttgccttgtc ctatcgaaat agtctcaaat tatccttgat
    11701 tggcatcttt atgagtctag cagctgtggc caagattctc cttgggactg tgctacttgt
    11761 agcaattggt tactatatgc ctgccctgct attttttgta ggaattggga tgtggcattt
    11821 ctttatcagt gatatgttgg aacctgtcta tgaaatcatc catgaaaaat tggcgacaaa
    11881 atagaatgaa gcagttttgg ctacatacgc ttctaagaac ctatagttca gtgatgatca
    11941 ttatcattgc gagttttgca atcttactct cttacgctga ctgggattca cgtgaaaagg
    12001 aagcccagag agtagcccag cgtgtaactg ctagaacagt gagtgaaatt gaatattacc
    12061 atagagagtc aacccagata gctcaggctt tagttgaaaa ccaagctcgt attgagggaa
    12121 tctataaata ctttagtctt agcatgccag actattttta ctggcaatta gagcggaaag
    12181 cttcgcctta tatatcagtc tctctgtatg aaaatgttga tgacctctat gttcgaaatg
    12241 attttgtaac tggagtggcc attgcttttc aagattacaa ggaagtctat gtttctacta
    12301 aagacaaacg tagtggagaa aaaatcaggg ctgaggattt caaaccagca ggaaatagtt
    12361 ttgccattcc ggtgtcagat ccagtgtcag atcaagattt aggagtgatt tacatctcct
    12421 tggatcctgc tgttttatac catgccattg ataatactag aggtcatact ccgatggcag
    12481 taacagtgac ctcacctttt gatacggaga tttttcatat tggtgagaca gttgataagg
    12541 agagtgaaaa ttggctagtt ggcttaactt ctcatggata tcaggttcag gtggcagttc
    12601 ctaaaaactt tgttttacaa ggaacagtga ctagctctgc tttgattgtg ggtttgagcc
    12661 ttctctttat tgtcattctt tatctgactt tgaggcagac ttttgctaat taccaaaagc
    12721 aggtagtgga tttagtagaa tccattcaag tcattgctca aggcgaagag gggcgtcgga
    12781 ttgacatttc cgagaaagat caggaattac tcctaatcgc ggagacgacc aatgatatgt
    12841 tggatcgatt ggaaaagaat atccatgata tttaccagtt agagcttagt caaaaagatg
    12901 ccaatatgcg agccttgcag gcgcaaatca atcctcattt tatgtataat acgctggagt
    12961 tcttgcgcat gtatgcagtt atgcagagtc aagatgagtt ggcagatatc atttatgaat
    13021 tcagtagtct cttgcgtaac aatatttccg acgaaagaga gaccctcctc aaacaggaat
    13081 tagaattttg ccgtaaatac agctatctct gcatggttcg ctatcccaag tccattgcct
    13141 atggtttcaa gatagatcca gagttagaga atatgaagat tcccaagttt accttgcaac
    13201 cgctggtaga aaactatttc gcgcatggtg ttgaccacag gcggacagat aatgtgatta
    13261 gcatcaaggc tcttaaacag gatggttttg tggaaatttt ggtggtcgat aatggtagag
    13321 gaatgtcggc tgaaaagttg gcaaatatcc gagaaaaatt aagtcagaga tattttgaac
    13381 accaagccag ctacagtgat caaaggcagt ctatcgggat tgtcaatgta cacgagcgtt
    13441 ttgtgctcta ttttggagac cgctatgcca ttactataga gtctgcagag caagccggtg
    13501 ttcagtatcg tattacaatt caagatgagt agaaagggag aaaatgtata aagtattatt
    13561 agtagatgat gagtacatgg tgacagaagg tctgaagcgt ttgattccct ttgataagtg
    13621 ggatatggag gttgtcgcaa cagccagtca tgccgatgaa gctctagaat atgttcagga
    13681 aaatcctgtc gatgtcatca tttccgatgt caatatgcca gacaaaacag ggcttgatat
    13741 gattcgggag atgaaagaga tcttaccaga tgctgcctat atcctgctct caggttatca
    13801 ggagtttgat tatgtaaaaa gagcaatgaa ccttagtgtg gtggactatt tggtcaagcc
    13861 tgttgataag gtagagctgg gaaatctgct ggagaagatt gcaggtcagc tcggcgagag
    13921 agggaagaaa agtcagactc ttagtcaaga attagacgag gctggatttg ttagttattt
    13981 aggggataag gagaattggt ggataggtct atccaaggaa aaacaaggtt ccttcaccat
    14041 tccctactat gtcttgggcc aagactggca gattttcatt tctggccaac ctctagatgg
    14101 tttagtcgtt acaccttttg aagctcctta tcaagaacac tttgaacgct ggaagctgaa
    14161 tgctgagaaa accctctttt acggttctgt aaatttgcag cagtctgaga gtctctttgc
    14221 ctattacgaa ccgatttata gggttatcat tcagggaaat ctcaatcaaa tcgtagaaga
    14281 gttaaatctc ttggagaagg tagttcttga aaatacgccg cgtgttccga ttactaaaca
    14341 gctttttatt cagtttgtca tggatgtttt ccatttattt gaacatctca aagctgatga
    14401 cctgacagac atcgtcaaaa ccattcatgc tattcaatcc ttcgatgaat tggtttctta
    14461 tatcaaggaa actctgatca gctttttcgg tcaataccgt atgaatgaaa atgtggtcag
    14521 tgtgctggaa gtcattggtc gtgattacca aaaagagctt tccctcaagg atatcagtaa
    14581 ggctctcttt atcaatcctg tttatctagg gcagttgatt aagcgtgaaa ccgattcgac
    14641 ttttgcagag ttactaaaca aacaacgtat taaggctgcc caacaacttt tgctttcaac
    14701 tagtgacagc atcgaagata tttgttatgc tgttggttac agtaaccttg gatatttcta
    14761 taaagttttc cgaaaattgt gcggaaaatc gccaaaagcc taccgaaaac aggtagaaac
    14821 tatactataa gatttgtatt cctttacaaa aggtgctata atattatcag gaggttctat
    14881 catgaaaaag aaaccaattt atctatgggt cttgctaatc ttgtctgccc ttatttcagt
    14941 tccgtctctg tttggaattg tgagtccctt gcctagtaaa gaagcccttc gtgctgctca
    15001 gaaacaagtt gcaggggtca atgctcagca attagaagac cagcttaatt atacctatag
    15061 agtagcagaa gcatctcatt ctatttttaa tgttgctttg attgtgctat ctactatttt
    15121 agtggtcgta gcgattgtct tccttgttcg taaaaatttg caatatgcaa actatactta
    15181 cgttggctat gttttgttag ctattattgg ttcgatttat ggctatgttg gtttacaaga
    15241 cgctgtgcag ttggttcaag atgagagcat gcgtttgaca gtgagtattg gttcaaaagc
    15301 tgttagcatt ttctatatcg tcatcaatgt tctcttccta gcccttgtct tctataagat
    15361 gtggcgacaa cagaaagcct tggcagaaga agaggaaaca gaagagctta cctaagtatt
    15421 gacaaaaaag aactatcaag atacaatctt ggtagttgtt ttttgattat agataaaatc
    15481 atggaggtac atatgaagac aatttcttta gtttatatta gtttgagtgg caacactgaa
    15541 agttttgtga cgcgcttgaa agactatctc ttgtcccagt acaaagggat tgaggttcaa
    15601 aagattcata tcaaggattt ggtcaaggaa ggcaaaaatt tctatgaaat ggaccatccc
    15661 tatgtcgctt ttttgccgac ctatctcgaa ggtgggaatg gcgtggataa cggagatgtt
    15721 gagattttga cgacaccggt gggagatttt attgcctatg gtaacaatgc tagtaagtgt
    15781 tttggtgtgg ttgggtcagg aaatcgtaac tttaataacc aatactgcct aacagccaag
    15841 caatacagtc aacgctttgg cttccctgta ttggctgact ttgaaatgcg aggcatgctg
    15901 gaagatatca aacatgtcgc agctattatc gcagatttgt atgagttgga aaaggagaat
    15961 taatactcaa tgaaaatcaa agagcaaact aggaagctag tcgcaggttg ctcaaagcac
    16021 agctttgagg ttgcagatag agctgacgtg gtttgaagag attctcgaat agtataaagt
    16081 tcttataaga tgtggttgaa gttgttcaac tgttttttga gtataaacag tctttaagaa
    16141 cgtaaaaaag cataagttca ggtcttcaaa accttgttct tatgcttttt atcatagaaa
    16201 tatttgctga attttctctt gaaatgaaac cttatcttca tctcgcgctt gtcccttacc
    16261 ctgcttttcc gattgcgagt gcgtagataa agaagatggc gaagccaaag aggaaaatca
    16321 atcccgcaat ggcaaggtgt ttgagccaag aaggaagatt tttgttttca cgtgttacca
    16381 aggcgtaatt caaaagagca aagaaaggtg ttgtcaggaa agagccaatc atggcaaagc
    16441 ggagcatggt tgaaacctga ccagcgaaga acttgataat gacgataccg atgatagcag
    16501 tgatggtcat ccagatgttc aaagatttac gattgtcctc tttttgactg attagcagtc
    16561 ggagagattc ctgattaacg cgagaatagc catcgataac agttataact gttccaaaga
    16621 tacagaggaa ggcaataaag gtaatcaagt aacgggacca ttcgccaaga acagaggcat
    16681 acatgcccac gaattgagag atgtatttgg ctgaagcagc ttcaaccgcc tgccctgtag
    16741 gatactgaat cagtgctccc agtgccacaa agaagacggc taggatagct gttccaatat
    16801 aaccagtgtt aaagtcaaac agagcgtctt ctgtgttaaa gttgacggtc tttctctttt
    16861 cagctgacca aagtgaattg atggctgaaa tttcaatagg agccggcatc catcctagga
    16921 gggagacgat gaagggcaga gctgccattt gccaaggtgt cttctcgaca aaatcagaac
    16981 tgtattctgg atgcttgacc gccgcaatga taactgcaag aacagtcgca atggttaagg
    17041 cagacataat ccatttgacc atgccgtcta aaagtttgta gcctccaaag agtagcatag
    17101 cccaaatgat tgcaacgaga atgagggacc actgagtaat gctaagtcca atcattggga
    17161 aggcactggc gatgatagct gagcacagaa tggcaacacc agccgtgttg accatagccg
    17221 aaaagacatt gagaataaag aaaatccaga gatagagttt tcctttttcg gcataacctt
    17281 caaccaaagt ctttccagta tcagctgtgt attcagcacc aaaacggaaa aatggatatt
    17341 taaagacatt ggctaagatg accaagagaa gtagagacca accgtaagaa ccgccagctt
    17401 gagttgagga tacaatgtgg gaacctccaa cagcggcagt tgccattagg attccaggtc
    17461 ccattgcttt tagcttgctt gcccaggttg attgatttaa ggaaatagct tgcgacatga
    17521 taaatactcc tttttgaatt ttcagaataa tctgtatatg caatctatat tctacaaaaa
    17581 attttggaaa aatgcaagaa tattttgaaa aaagatagaa aatttacaaa gaaaatctga
    17641 aataactgtt atgatatagc agattgaaac tagaatagta cacttttgct tctaaaacat
    17701 tgttagaaat cgatttgact gtcctgattg atttatcctg ttcttatttc atttcactat
    17761 agtaaggtgc agcaggataa agcaaaaccg agaagtttct ttctcggttt tgcttattat
    17821 gaggttccta ttttctatgc tccaagagtt gattgatgtg atctactttt ttagcctctc
    17881 ttttatagag aatagcccag atgatgagat agacaatcgc aaactcgata atgagctgga
    17941 ggtagaaaat ccagtggaag gggaaccaac cagcaagagt tgctagtggg acaaagccag
    18001 ccagcataag gaagaaatga gtcagagtgg cacgaagcat gctccagtca cggctgaata
    18061 agcggttgcc aaagttgaag agcataccga tggctgccca gataagtgtg cagtagagca
    18121 agaccagggc accgtgaacc tgatgctgat ccatcacttg gccgatgaga gagtagggat
    18181 ttagtggtgc gtaggtattt ggtgcataaa tgagtgaaaa gaggatggag aggatgaggc
    18241 cgataagaac accggcagct gcatcgtgaa atacttgttt tttcatagtt ctaatttctc
    18301 cttgatggtt tttagataac ggcgtgaaga gtaggtgaag ctttcgtttt tcaagaaaat
    18361 ttctaccaga ccgtttggcg tgagcttgag gtgagagatg gaatcgatat tgatgatttc
    18421 tgattgggaa atttggataa aattgcttgg caagagttta agaacctgat agagtcgcaa
    18481 atcaatgctg taggtctgac tcgcggtttc tgctagaacc ttccgattct cgatatagaa
    18541 gcgctgaatc ttgccaatct caactagata gacctgatca tcgatttttc ctttgatttt
    18601 ttctctttgg tccagatttt ctgcgaactc gatgactttc tggacttttt cggtttcttg
    18661 aggtgcttgg acaatcagct tttcctcctc gtaagtctca ctaatctgta gttctacttt
    18721 cataaatttc tctccttgtt tttcatacaa aattaatctc acttcttgta cacctttatt
    18781 aatactcttc aaaaatctct tcaaaccacg tcagcgtcgt cttgccgtag gatagttgtt
    18841 gactttgtca gttttatcta caacctcaaa acagtgtttt gagctgtctg cgtctagctt
    18901 tctagtttgc tctttgattt ttattgagta taccactatt ttactccctc tggcaaggga
    18961 ctttgtctat gtggagggat tgggctccta tgtggtggag tttttctgtt ctttctgaaa
    19021 tatggtataa tagcactaat taatttctag gaaaatagat acagaaaggg gctgaaagat
    19081 gtctcatatt attgaattgc cagagatgct ggcaaaccaa atcgcagctg gggaggtcat
    19141 tgaacgtcct gccagtgtgg ttaaagagtt ggtagaaaat gccattgacg cgggctctag
    19201 tcagattatc attgagattg aggaagctgg tctcaagaag gttcaaatca cggataacgg
    19261 tcatggaatt gcccacgatg aggtggagtt ggccctgcgt cgccatgcga ccagtaagat
    19321 aaaaaatcaa gcagatctct ttcggattcg gacgcttggt tttcgtggtg aagccttgcc
    19381 ttctattgcg tctgttagtg tcttgactct gttaacggcg gtggatggtg ctagtcatgg
    19441 aaccaagtta gtcgcgcgtg ggggtgaagt tgaggaagtc atcccagcga ctagtcctgt
    19501 gggaaccaag gtttgtgtgg aggatctctt tttcaacacg cctgcccgtc tcaagtatat
    19561 gaagagccag caagcggagt tgtctcatat cattgatatt gtcaaccgtc tgggcttggc
    19621 ccatcctgag atttctttta gcttgattag tgatggcaag gaaatgacgc ggacagcagg
    19681 gactggtcaa ttgcgccaag caatcgcagg gatttacggt ttggtcagtg ccaagaagat
    19741 gattgaaatt gagaactctg acctagattt cgaaatttca ggttttgtgt ctttacctga
    19801 gttgactcgg gctaaccgca attatatcag cctcttcatc aatggccgtt atatcaagaa
    19861 cttcctgctc aatcgtgcta ttttggatgg tttcggaagc aagcttatgg ttggacgttt
    19921 tccactggct gtcattcaca tccatatcga cccttatcta gcggatgtca atgtgcatcc
    19981 aactaagcaa gaggtgcgga tttccaagga aaaagaactg atgaccctgg tttcagaagc
    20041 tattgcaaat agtctcaagg aacaaacctt gattccagat gccttggaaa atcttgccaa
    20101 atcgaccgtg cgcaatcgtg agaaggtgga gcaaactatt ctcccactca aagaaaatac
    20161 gctctactat gagaaaactg agccgtcaag acctagtcaa actgaagtag ctgattatca
    20221 ggtagaattg actgatgaag ggcaggattt gaccctgttt gccaaggaaa ccttggaccg
    20281 attgaccaag ccagcaaaac tgcattttgc agagagaaag cctgctaact acgaccagct
    20341 agaccatcca gagttagatc ttgctagcat cgataaggct tatgacaaac tggagcgaga
    20401 agaagcatcc agcttcccag agttggagtt tttcggacaa atgcacggga cttatctctt
    20461 tgcccaaggg cgagatggac tttacatcat agatcagcac gctgctcagg aacgggtcaa
    20521 gtacgaggag taccgtgaaa gcattggcaa tgttgaccag agtcagcagc aactcctagt
    20581 gccctatatc tttgaatttc ctgcggatga tgccctgcgt ctcaaggaaa gaatgcctct
    20641 cttagaggaa gtgggcgtct ttctagcaga gtacggagaa aatcaattta ttctacgtga
    20701 acatcctatt tggatggcag aagaagagat tgaatcaggc atctatgaga tgtgcgacat
    20761 gctccttttg accaaggaag tttctatcaa gaaataccga gcagagctgg ctatcatgat
    20821 gtcttgcaag cgatctatca aggccaatca tcgtattgat gatcattcag ctagacaact
    20881 cctctatcag ctttctcaat gtgacaatcc ctataactgt cctcacggac gtcctgtttt
    20941 ggtgcatttt accaagtcgg atatggaaaa gatgttccga cgtattcagg aaaatcacac
    21001 cagtctccgt gagttgggga aatattaaaa gtataaaaaa gtctgggaaa aattttcaaa
    21061 atcagaaaaa cgcataaaat caggtgttca aaaaccttga ttttatgcgt tttatcatgg
    21121 aaatagttac ttcatgtttt cctaattctt ttcgaaactc tttttaaacc acgtcagttt
    21181 tatcagtaat ctcaaaacag tgttttgagc taattttgcc agttttgtct gtaacatcga
    21241 agttgtgttt taccactctg cgactggttt cctagtttgc tctatgattt tcacagagta
    21301 ttaaattgcg attttgccaa gtttctttat tcgtctaaaa gtagagtctg ttctatgcgt
    21361 ctaatgtacg aattaggttg accatttcaa tagctccttg tgcacactca gaacccttat
    21421 ttcctgcttt ggtaccagct cgttctatgg cttgttcaat tgtatctgtc gttagcacac
    21481 caaacataac aggaatttcg ctatttaaac tgatttgggc gattccctta gatacctcgc
    21541 tacatacata atcataatga cttgtattcc ctctaatgac agctcccaag cagataattg
    21601 catcatattt tttacttttt gccatttttg atgcaatcag tggtatttca aaagctcctg
    21661 gaacccaggc tacctctata tctttctcgt ttacattctc tcttttgaga ttatctagtg
    21721 ctccagataa taattttgaa gttataaatt cattaaatct cgctacaaca atacctattt
    21781 taatattgtt tgctactaaa ttaccttcat aagtgttcat ttatttttcc tccatattta
    21841 aaatgtgacc cattcgattt ttctttgttt ctaaataaaa actatcgtaa ggattggctt
    21901 ctatttcgat tgatattcta ctggaaatgg taattccata tttttctaac tgttcaacct
    21961 tgtcaggatt atttgtcagt aaatgaagtg actgaagtcc cagatcttta agcatttgtg
    22021 ctccaatatg atattctctt aaatcacctt caaagcctaa tgcaagattg gcatcaagcg
    22081 tatccatgcc ttgatcttgt aaatgatagg cttttaattt attgataagt ccaattcctc
    22141 gtccctcctg tcgcaagtaa agtaagacac ccgaaccatt ctcaacaatc attttcatag
    22201 ctttatcgaa ttgctgtcca caatcgcaac gtaaagagcc taaaacatct cctgttaaac
    22261 attcggagtg gacccgacat aatacattgg cttcatcctc tatgtttccc ataataagag
    22321 caagatgatg ttccccattt agtttatcta tatagctaat tgctttgaaa ttaccgtatc
    22381 tagtaggcat attgacagtt gaaactcgtt ctatcagctg atcatatact tttctatatt
    22441 cttgtaattc tttgatggta attagtggaa tgttgtgttt cttcgagaac tgaattaaat
    22501 catctgttct catcattttg ccatcatgat tcattatttc acaacatagg ccacactctt
    22561 ttagtccagc taattttaat aaatcaacag ttgcttctgt gtgtccattt ctttctagaa
    22621 caccaccttt ttttgcaatt aaaggaaaca tgtgtcctgg cctgcgaaaa tcagagggtg
    22681 ttatatcttc agctacacac atacgtgcgg tcagtcctct ttcctcggca gaaatacctg
    22741 tggtcgtttc tttataatca attgaaactg taaaagcagt cttatgatta tctgtattgt
    22801 tttcaaccat aggtgaaagc attaattgat tagctaaact ttcgctcata ggcatacaaa
    22861 ttaatccttt ggcataagta gccataaaat taacattttc tgttgtagct gcttgtgcag
    22921 aacaaattaa gtctccttca ttttctctat ccttgtcgtc tataacaaga acaagtcgtc
    22981 ccttctgcaa tgcttctaat gtttcttgta tttttcgata ttccattgac tgattatcct
    23041 ttctgctaaa atccattttg atataatagt tccttagata tttctgattt tggagagtta
    23101 tccatcagtt tttgcacata tttacctaag atatcatttt caagatttac tgtactcccg
    23161 acttgtttac ttttaagaat ggtttgtttc aaggtatgag ggataacaga tactgaaaag
    23221 tttactttgg agactttagc gacagtcaga ctaatgccgt caattgtaat agatcctttt
    23281 tcaactatta aatctaaaat ttctttttgt gtgttgattt gataccatac agcattatca
    23341 tcttttttta ttgacgagat ttttcctgta ccatcaatgt gtcctgtaac gacgtgaccc
    23401 ccaagtcgac cgttgataga taaggctctt tctagattca cctcacttcc atgttttaat
    23461 agagtaagag ctgttcgact ccatgtttca ttcattacat caactgtaaa ggattgatga
    23521 ttgaaatgag taactgtaag acagatacca tttactgcta tactatcgcc taaatggata
    23581 tccgttaata tttttgaggc tttaattgat agtttacaat tacgagagtc tttctgtatt
    23641 ctttcaactt ttccgatttc ttcaattatt cctgtgaaca tggataaatc acttcacttt
    23701 ctatgagata gtcatttcct atttgagaaa aagcataagg tttcaatcta atagcgtcat
    23761 ttggcaaaga aatgccttca cctccgacag gaaacttggc actgcctcca aaaatttttg
    23821 gtgcaatata tattttcagc tcatcaacaa tttgttgttc caaagcactc caattcatta
    23881 gactgccccc ttctagaact aggctatcaa tctgcatgtt tcctagatgt tgcattaaac
    23941 tcgataagtc tatatgattg ccttttttct ttatggaaag tatttcacag ccatgatttt
    24001 gatatagctt cattttattt ttgtcttcag aggaagtggc aatgtaagtt ttaatatcat
    24061 ttgctgtttt tacgatttta gaggtaagag gagttcgtaa atgtgtatcg catatgatac
    24121 ggataggatt tttcccttcc tccaatctac atgtcagcaa aggatcgtct tgaataacag
    24181 tattgactcc caccataatt gcactaacat ggtgtcgtaa ctgatgcaca tgctttcttg
    24241 cttcttcttc agtaatccat ttggattgat ttgttttagt ggctattttt ccatccattg
    24301 acattgcata tttcataaaa acatagggta catgctgggt aatatacttt ctaaaacttt
    24361 ttattaagtt aagacactca ttttctaaaa ttccaacagt aacttgaaga ttattttcct
    24421 caagtatctt tactcctttt ccagatacaa taggattaca gtctaggctt ccaatgacta
    24481 ctcttgtaat accactatcg attatagcat ctatacaggg aggtgttttc ccgaagtgac
    24541 aacagggttc aagtgttaca taaagcgtcg ctccgacagg ggattctcta cagtttttaa
    24601 gagcatttct ctcagcatgt gggccaccaa aaaactcatg ataaccttgt ccgatgatgt
    24661 gattatcttt tacaataact gcgccgacca taggattggg attgacgtaa ccagcccctt
    24721 tttgtgccag ttttattgct aatttcatat attttgaatc gctcatctca ctacctccaa
    24781 aaaaatatac cttgaatagg ggactactca aggcatacaa aagaaaactt atgcgattaa
    24841 caaaaatact ctgaaatgac aagtaatcat ttcagagcac gcaaaaagca caaatatact
    24901 tttatcttct ttcatccaga ctatactgtc ggctttggaa tttcaccaaa tcatgccttt
    24961 cggctcgtgg gctataccac cggtagggaa ttacaccctg ccctgaagat agttattcaa
    25021 ttacagatga ttatagtact taattttgaa tatgtcaaca gataaatacc gattgttttt
    25081 gatatactgt atttgtgata atcgattctc gctcctcgga taaagaaaat atgatatact
    25141 agataaacga aataagagag aaggaatact atgtacgcat atttaaaagg aatcattacc
    25201 aaaattactg ccaaatacat tgttcttgaa accaatggta ttggttatat cctgcatgtg
    25261 gccaatcctt atgcctattc aggtcaggtt aatcaggagg atcagattta tgtgcatcag
    25321 gttgtgcgtg aggacgccca tttgctttat ggatttcgct cagaggatga gaaaaagctc
    25381 tttcttagtc tgatttcggt ctctgggatt ggtcctgtat cagctcttgc tattatcgct
    25441 gctgatgaca atgctggctt ggttcaagcc attgaaacca agaacatcac ctacttgacc
    25501 aagttcccta aaattggcaa gaaaacagcc cagcagatgg tgctggactt ggaaggcaag
    25561 gtagtagttg caggagatga ccttcctgcc aaggtcgcag tgcaagcaag tgctgaaaac
    25621 caagaattgg aagaagctat ggaagccatg ttggctctgg gctacaaggc aacagagctc
    25681 aagaaaatca agaaattctt tgaaggaacg acagatacag ctgagaacta tatcaagtcg
    25741 gcccttaaaa tgttggtcaa ataggagcag agaatgacaa aacgttgttc gtgggtcaag
    25801 atgacaaacc cgctctacat cgcctatcat gatgaggagt ggggtcagcc cctccatgat
    25861 gaccaagcat tgtttgagtt gttgtgtatg gaaacctatc aggcaggcct gtcttgggaa
    25921 acggtactca acaaacgcca agctttccga gaagcctttc atagctatca aattcactca
    25981 gtcgcagaga tgactgagac tgaattggaa gccatgctgg agaatccagc tatcattcga
    26041 aatagagcca agctttttgc tacacgcgct aacgcccaag tccttctaca gttacaggca
    26101 gagtacggct cttttgatgc ctatctttgg tcttttgttg aggggaaaat tgtcgttaac
    26161 gatgttcctg attatcgcca agcgccagct aaaacaccct tatctgagaa attagccaaa
    26221 gatctcaaaa aacgaggctt caagttcaca ggcccagtcg ccgtattgtc ttttctacag
    26281 gctgcagggc tagttgatga ccacgagaat gattgtgagt ggaaaggtct taaatgatgt
    26341 ctaacaaaaa taagggaatt ctgatttttg cgattctcta tacagtcctc tttgtgtttg
    26401 atggcgttaa attgctggct tctttaatgc catctgtcat tgcaaattat cttgtttatg
    26461 tagttttagc tttatatggc tccttcttgt tcaaggatag attgatccaa caatggaagg
    26521 agattagaaa gactaaaaga aaattcttct ttggcgtctt aacaggatgg ctctttctca
    26581 ttctgatgac tgttgtcttt gaatttgtat cagagatgtt gaagcagttt gtgagactag
    26641 atggacaagg tctaaatcag tctaatattc aaagtacctt tcaagaacaa ccactactga
    26701 tagctgtttt tgcttgtgtc attggacctc tggtagaaga attatttttc cgtcaggtct
    26761 tattgcatta cttgcaggaa cggttgccag gtttactaag cattattctg gtaggacttg
    26821 tttttgctct gactcatatg cacagtttgg ccctatcaga gtggattggt gcagttggtt
    26881 acttaggtgg aggccttgcc ttttctatta tttatgtgaa agaaaaagag aatatctact
    26941 atcccctact tgttcacatg ttaagcaaca gcctctcctt aatcatttta gctatcagta
    27001 tagtaaaatg aaatgagaac aggacaaatc gatttctaac aatgttttag aagtagaggt
    27061 gtactattct agtttcaata tactgtaata tgtgatgaaa atgccagtaa tgataccgag
    27121 aaaaaagctg agaaactttt cccagcttta tttgttatag tcaaagagaa tgacttgttc
    27181 ctgtgcatct acatgagcat ggaccccaaa gggtacaatt gctcttggag ttgcgtggcc
    27241 gacattcaga ttatagacaa tcgggatatt gctgtcaatg atatccaata gtgcctcttt
    27301 atagtcgtca tggaaagttt catccatagg ttttccgacc aagagtccat tgatgaccgc
    27361 gaatatgcca gtgtccttta aagttagcaa catctttttg aagtcttctg gcttaggctt
    27421 ttcttcgctt gtttcgagca agaggatttt cccttcccag tctgacaagt cagggaaaag
    27481 tttgtatttt tggcagagtt ccgtgctatc tgcgtatcga gagttgtcaa agatatcgta
    27541 gagggattcg aggcaaccac cgaggatttt cccctcgaac tgggcacttc cttgcaacaa
    27601 gtcaaaacct gtatttgtat gactgacacg aggtgttccc agggccgtgg gactaaaatc
    27661 agttcgttcc tcataccaaa cgtcactagg gcggatttct gaaattcttc ccgtctcaat
    27721 caattcttta aagtagtgaa ggctataggc tagcatttct ttgtctaatt cacaaatgtc
    27781 tgctaaaaag gattgaccat aaaaagtctt gattcctaat ttatgcaaca tgaggtggtt
    27841 catggttgta tccgagaagc caagaaaaat tttttgtttg ataacctttt ggagttggtc
    27901 attttcaaaa agataaggta gcaagcgata ggtatcgtct ccaccgatgg cacataggat
    27961 catgtcgatg ctatcatcag aaaaggcatg aatcaaatcc tctgcacgag cttcaggatg
    28021 gtccttgata aagtctaatc cttttaacga atggggcaaa aagatgggat tgagtcccag
    28081 atccttgaga cgttggatac ccaagtccac ttcgtgtttg acaaaatcct ctccgataat
    28141 gccactagat aaactaacaa taccaatagt agaaaccata tctcatcctc ctagaaatag
    28201 attgagccta ttttatcaca aaatataaga gaaagctatg tgggatttca gaagaatact
    28261 tttaatactc ttcgaaaatc tcttcaaacc acgtcagttt tatttgcaac ctcaaagctg
    28321 tgctttgagc aacctgcagc tagcttccta gtttgctctt tgattttcat tgagtataac
    28381 tcaaaaaagt aagtgaaaaa gcaaccgcac ctgcagttgc ttttatcgtt ttcttattct
    28441 tgatagcgtg ttggtcctgc acttgcacta cggatattca agcgtttctt gagatagaag
    28501 cgaagggcta ggagggctac tccaataata gctagtggca atggatccag tactgggtta
    28561 aggctagctg gtaggaagct tgttgcaaag aagacaagca accaaaggaa catagaagtt
    28621 aggataacta gtacagattt ccagaaaggt ggacgttgac tgcgatccat atctggtcca
    28681 tagtattggt aaacaaagta gtacatcaag tagaaggcaa atccaccaac cagtccaact
    28741 aatagaagag taatcaatcc atagccgaaa gcttgatctg ccgcaaagaa ggttgtgagg
    28801 gcgctgacaa gggcaaagag gctagtgatg aaaagagctg agtccataat catcagtttt
    28861 ggatcatcat tttcttttgg atgctctttt tcgtactgct ctttgacagt gaagctatga
    28921 gcccaatgag ttggtgcgcc gtatagggaa cgggcagttg tacctttaga ttgctcctca
    28981 aggatttggg gaatgacttc ctcaaaaata gtctggattt cagcgtctgt tttcccatct
    29041 ttgatgaatt gttgggtagc aatgtggaca aactcttggt ttttcttagt taatttttgt
    29101 agatcaattt gagacatagg aactcctctt agaaccattt tttatggatg agatagagag
    29161 tgagcgagac actcatagca aaggcgataa agacgattaa ccagaaggca tttggctctc
    29221 cgtttagggg aatttcatta tccttaaagt tcatcccgta ggcagaaaag accatggttg
    29281 ggatggacat gacgatggtc acaagggcca aggttttcat gatgttgttc tggttgttag
    29341 aaatgataga ggcaaaggtc tctgtcatag aatgcaagac gtttccataa atatctgcca
    29401 tctcgatggc ctgttgggtt tcaatcaggg tgtcttcaag caggtcttcg tcctcaaggt
    29461 atttcttgat attgctggtt gaactggtca atttcttaat cacgcgctca tttgttttga
    29521 gggaggcctt gaaatagacg atagtttttt ccaattccat gagctcaatc aattcttcat
    29581 tacgagttga ttgatgcagt tgactttcga tttgttcact cttgcggtcg attgaacgaa
    29641 gggctgttag gtaaagctct gcattgcgat aaagaatttg aaagataaaa cgtgaacgca
    29701 tgaaggtata gaaattacgc aatcgacggt tgataaagac atcaaggaca ggtagtggtt
    29761 ccaaacacgt agtgataatg gtttcctcag tgatgataat accaagcggg atggttacgt
    29821 agtaggtgcg gttatttctt tcctccgtga ccggcacgtc tacgataatc agggtatact
    29881 cgtcttcaat ggtaatacga gacatttctt ccgcatcgag cggtgctcga aggtcggcaa
    29941 tatcaatatc gaaggtgttg gcgatttcga gtgattcatt ttgagtcgga ttgacgagat
    30001 tgatccaagt acccggttca agcgtatcga tctctttaaa ttcagttgtt gtagagagaa
    30061 aaacttgttt catatccctt atcctttctc atttttcaga ttttttcaca ctgtactatt
    30121 atactacaaa atcggccttt tgggtaatag aatctcactt tttttggtat aatggtaagc
    30181 aataatggac tagaaagaac aaagatgcaa gataaaattg tcattcatgg ggcgcgtgcc
    30241 cataatttaa aaaatattga tgtggagatt ccgcgagaca agttggttgt cgtgactggc
    30301 ttgtcaggtt cagggaagtc cagtctggct tttgatactc tctatgcgga gggacaacgt
    30361 cgctatgtag agagtttgtc tgcctacgct cgtcagttct tgggaaatat ggaaaaacca
    30421 gatgtagatg ccattgatgg tctcagccca gctatttcca tcgaccagaa aacgactagt
    30481 aaaaatcctc gctcgacggt gggaacgacg actgaaatca atgactatct gcgtctcctc
    30541 tacgcacgtg tggggacgcc ttactgtatc aacggacatg gagctatcaa tgcttcttct
    30601 gtggagcaaa tcgttgataa ggttttggag ttacctgaac gccagcgctt gcagatcttg
    30661 gctcctgtca tccgcaagaa aaaaggccaa cataagagtg ttatcgagaa ggttcagaaa
    30721 gacgggtatg ttcgtgttcg tgtggatggg gaagtctatg atgtgaccga agtgccagag
    30781 ttgtctaaga gcaagcaaca caatatcgat gtcgtggttg accgtattgt tatcaaggag
    30841 ggcattcgta gccgtctctt tgattccatt gaagctgccc ttcgtatcgc agaaggttat
    30901 gtgattatcg acaccatgga cgactctgag ttgttgttct ctgagcatta tgcctgtcca
    30961 gtttgtggat ttactgtccc agagttagaa cctcgtctct tctctttcaa tgctcccttt
    31021 ggctcttgta gtgagtgtga cggcttgggg attaagctgg aggtggatac tgatttggta
    31081 gtgccagatg ccagcaaaac cttacatgag ggagcgctgg caccttggaa tcctatctca
    31141 tccaactact atccaaacat gttagagcag gccatgaaag tctttggagt ggctatggat
    31201 aagccttttg aggacctgtc agaagaagat aagaacttga ttctctacgg ctcagatggt
    31261 aaggaattcc atttccatta tgaaaatgaa tttggtggtg tgcgcgatat cgacattccg
    31321 tttgagggag ttatcaataa tatcaaacgt cgttaccatg aaaccaatag cgattacact
    31381 cgcactcaga tgcgtctcta catgaatgag ctgacctgcg gaacctgtca aggctatcgt
    31441 ctcaatgacc aggccttgtc tgtccgtgtg ggcggccagc aagggccaca tattggagaa
    31501 atctcagacc tgtctatcgc tgaccacttg gacttggtga gccagttaac tttgtctgaa
    31561 aatgaagcca tcattgctcg tcccattctc aaggaaatca aggatcgttt gaccttcctt
    31621 aataatgtgg gtcttaacta tctaaccctg tcacgttcag caggaaccct ttcaggtggg
    31681 gaaagtcagc gcattcgttt ggcaacccag attggttcca acctatcagg tgtcctctat
    31741 atcctagacg agccgtcaat cggtcttcac cagagggaca atgaccgcct gattgccagt
    31801 ctgaaaaaga tgcgtgactt gggcaatact cttatcgtgg tggaacacga cgaagatacc
    31861 atgcgtgaag ctgattatct gattgacgtt ggtcctggtg ccggtgtttt tggtggtgag
    31921 attgttgcag caggtacacc taagcaagtg gctcgcaaca gcaagtctat cacaggtcag
    31981 tacttgtcag gcaaacgtgt catcccagta ccagaagagc gccgtgtcgg aaatggtcgt
    32041 tttattgaag tgacaggagc gcgtgagaac aacttgcaaa atgtcacggc tcgctttcca
    32101 ctaggaaaat ttatcgcagt gacaggtgtg tcgggttcag ggaaatcgac tctaatcaac
    32161 agcattctca aaaaagccat tgcccagaag ctcaaccgta attcagacaa acctggtaag
    32221 tttaagacta ttacagggat tgagcatgtc gaccgtttga ttgatattga ccagagccct
    32281 atcggacgga cgccgaggtc taacccagct acctatacag gagtttttga cgatatacgt
    32341 gacctttttg ctcagacaaa tgaagccaag attcgaggct acaagaaggg gcgcttcagt
    32401 ttcaacgtca agggaggtcg ctgtgaagct tgctcaggtg acgggattat caagattgag
    32461 atgcacttct tgccagatgt ttatgtggct tgtgaagttt gccacggaac ccgctataac
    32521 agtgaaaccc tagaagttca ctacaaggaa aagaatattt cgcaggtctt ggatatgacg
    32581 gtcaacgatg cggtagaatt tttccaacac attccgaaaa ttcaacgcaa actccagacc
    32641 atcaaggatg taggtctagg ctatgtgacc ttgggacagc cagctaccac cctttctggg
    32701 ggagaagccc aacgtatgaa gttagctagc gaactccaca aacgctcgac aggaaaatct
    32761 ttctacattc tggatgagcc gacgacaggg cttcatacag aggacattgc tcgcctgctc
    32821 aaggttttag ctcgctttgt agacgccggc aatacagtcc tcgtcatcga gcacaatctg
    32881 gatgttatca agacggcaga ccatatcatt gacttgggac ctgagggcgg tgtcggtggt
    32941 ggaaccatca tcgtaacagg aactccagaa gaagtagctg ccaacgaagc cagctataca
    33001 ggacactatt tgaaaggaaa gttacatcat gaataaacgc gtacaagcat ttctagctaa
    33061 aatgcaagaa aaagaactag atggtatcat catcaacaat cttaaaaacg tctattattt
    33121 gactggtttt tggggctcaa acggaacagt ctttatcagc cgtgaccgtc aggtcttagt
    33181 gacagactct cgctatatca tcgcagctaa gcaagaaacc agtggttttg agattgtggc
    33241 tgatcgtgat gaattggctg tcattgcagg aattgttaag gacatgaact tgactcgtat
    33301 cggttttgaa gatgagattt cagtgtctta ttaccaccgt atgcaggcag cttttgcagg
    33361 tttgaacttg cttccacaaa ctcagtttgt ggaaggtctt cgtatgatta aggatgaggc
    33421 agagattgca gcgattcgca aggcttgttc tatctcagac caagctttcc gcgatgcgct
    33481 tgactttatc aaaccaggaa aaactgaaat tgagattgcc aacttccttg atttccgcat
    33541 gcgtgagttg ggagcatctg gcttatcttt tgatacgatc ctagctagcg gtatcaattc
    33601 ttctaaaccc catgcccatc caatgcacaa accagtggag ttgggagaag ccattaccat
    33661 ggacttcggc tgtctctatg accactatgt cagtgatatg acccggacta tctatctagg
    33721 gcatgttagc gatgagcagg cagagattta caatacggtt ctaaaagcta accaagcctt
    33781 gattgaccaa gctaaggcag gcttaggttt ccgtgacttt gacaaaatcc ctcgtgatat
    33841 tatcattgag gcaggttatg gtgactactt tactcacggc attggccacg gtattggtct
    33901 ggatatccat gaggaaccct actttagtca gacttctaca gaaactatta agacaggtat
    33961 ggccttgacc gatgaaccag gtatctatat cgaaggcaaa tatggcgttc gtatcgagga
    34021 tgatatcctg attacagaga caggttgtga attattgacc ctagctccaa aagagttgat
    34081 agtcatttag ttgtttgtca agaaaaaagt acgaaaatga cgaaaaaagt caaaaaaaat
    34141 taaaaatagg tcgcaagtcg gatgtttttt atggtataat agactaaact gatagtaaca
    34201 tgtagcgaaa ggggtaggta catgattaaa atttatacag tctcaagttg tactagttgt
    34261 aaaaaagcaa aaacctggct caatgcccac cagttaagtt ataaagaaca aaaccttggt
    34321 aaagaaggaa ttacgagaga agaattactg gatattctaa ccaaaacaga taacggaata
    34381 gccagcatcg tttcgtctaa aaatcgctat gccaaagccc ttggagtgga tattgaagat
    34441 ttgagtgtca atgaagttct caatctgatt atggaaacac cgagaatttt aaagagccca
    34501 atccttgtag atgaaaaacg cctgcaagtt ggctacaagg aagacgatat tcgtgccttc
    34561 ctaccacgct ctgtccgtaa tgtagaaaat gcagaagcac gtttgcgtgc agctctataa
    34621 acatcaaggc tgggagcact tcccagtctt attctatttt aatttcaaaa agaaagaaga
    34681 aagaaatgaa aaaaatagtt cttgttagtc tagctttcct ttttgtcctg gttggttgcg
    34741 gacagaaaaa agaaactgga ccagctacaa aaacagaaaa agatacgctt cagtcggcat
    34801 tgccagttat tgaaaatgct gagaagaata cagttgtaac taagactttg gtcttgccca
    34861 agtcagatga tggtagccag cagacacaaa caattactta caaagacaag acttttttga
    34921 gtctagctat ccaacaaaaa cgtccagtct ctgatgagtt gaagacttat attgaccaac
    34981 atggagtgga ggaaactcaa aaagctcttc ttgaagcgga ggagaaggat aagtctatca
    35041 ttgaagctcg taaattggca ggtttcaaac ttgaaacaaa actattgagc gcaacggaac
    35101 ttcaaacaac gactagtttt gattttcaag ttctggatgt caagaaggct tcccagttgg
    35161 aacatctgaa gaatattggt ttggaaaatc ttttgaaaaa tgaaccaagc aaatatattt
    35221 cagatagatt ggcaaatggc gcgacagaac aatagaaaat ccaaataaat agactgcctg
    35281 aattgtagaa ggtaaggaat tatgctataa tggtactatt ctaaggaaag agggtgttag
    35341 aatgggattt actgaagaaa cagtacgttt taaattggac gattccaata aaaaagaaat
    35401 tagcgaaact ttgacagatg tttatgcttc gttgaacgat aagggttaca acccaattaa
    35461 ccaaatcgta ggttacgtat tgagtggaga ccctgcctac gttcctcgtt ataataatgc
    35521 acgaaatcaa atccgtaagt atgagcgtga tgaaatcgtt gaggaattgg ttcgctacta
    35581 cctcaaagga caaggagtcg atctataacc tatgagaatt atgggattgg acgtcggttc
    35641 aaaaacggta ggggtggcga ttagcgatcc gcttggtttt acagctcaag ggcttgaaat
    35701 catccagata aatgaagaac aaggccaatt tggttttgac cgcgttaagg aattggttga
    35761 tacttacaag gtggaacgat ttgtagtggg cttgcctaaa aacatgaaca atacaagtgg
    35821 accgcgcgta gaagctagtc aagcctacgg agcaaagcta gaagagtttt ttggtttacc
    35881 agtagactat caggatgaac gcttgacaac agtggctgct gagcgcatgt tgattgaaca
    35941 agcagatatc agtcgcaata agcgcaagaa agtcattgat aagttagcag ctcagctgat
    36001 tttacaaaat tatttagata gaaaatttta atataaagga gaggctatgt cacacgatca
    36061 taaccacgac cacgaagaac gtgaactaat cacactagta gatgagcaag gaaatgaaac
    36121 cttgtttgaa atccttttga caattgatgg aaaagaagaa tttggtaaaa actatgttct
    36181 tctagtacca gttaacgcag aagaagacga agacggacaa gttgaaatcc aagcttactc
    36241 attcattgaa aatgaagatg gaacagaagg cgaattgcaa ccaatcccag aagactcaga
    36301 agacgaatgg aacatgattg aagaagtctt caacagcttt atggaggagt gatacagtct
    36361 gggagactgt atcagcccaa ctccagaaat ggggaagagt tggaacgtcc agtgaacatt
    36421 tttaccccaa ctcttagaaa ttgagaagag ttggaacatc tagtggatgt ttttagccca
    36481 tattcacatt catagtagct agttattagc taaccaggta agaggtcggg agaaaatcct
    36541 ggccttgttt ttattagtaa ccatacttta atgcgataat tgattggact tttgtcaagg
    36601 agatgtgtat gtttgaagta gaagaatggc tccatagtcg gattggtttg aattttcgat
    36661 caggtttggg ccgaatgcag caagcggtgg atttgttagg aaatcctgag cagtcttacc
    36721 ctattatcca cgtaacaggg actaatggga aaggatctac cattgctttt atgagggaat
    36781 tatttatggg gcatggcaaa aaagttgcga cctttacctc ccctcatatc gtctctatca
    36841 atgaccgaat ctgcattaat gggcaaccta tagcagacgc agactttatc cgtttgactg
    36901 atcaggtcaa ggagatggag aaaacgcttc tgcaaactcc tgcccagttg tccttttttg
    36961 aattgctgac cttagttgct tttctttatt ttagggagca agaggtggat ttggttttat
    37021 tagaagtggg aattggtggc ttacttgaca cgaccaatgt ggtaactgga gagcttgctg
    37081 tcatcacctc cattgggctt gaccatcaag aaaccttggg tgatagtcta gaagcaattg
    37141 cagagcagaa agctggtatt ttcaaggctg gtaaaaaggc agtgattgcg aaattgcctc
    37201 cagaagctag acttgtctgt cagaaaaaag ccgaatcttt agctgttgac ctttatcagg
    37261 caggtcaaga tttttcagtg ctgaatggtg atttttcaag ctctttacta aatctttcac
    37321 agctgaacat aggcttagaa ggagcctatc agcaggagaa tgcggccttg gcgttgcaaa
    37381 cttttcttct ttttatggga gaaagaaagg aagctattga tgaacaggct gtaagaaagg
    37441 ccttggaaca gacccattgg gctggtcgct tggagcgtat tcgcccacag atttacttgg
    37501 atggtgctca taacctccct gccttgactc gcttggttga gtttatcaaa gaaaaagagc
    37561 aggaaggcta tcgacctcaa atcctctttg gatccttgaa acgtaaggat tatcaaggga
    37621 tgttgggtta tctgactgaa aatttacctc aagtggaact caaaatgacc ggctttgact
    37681 atcaagggtc tttggacgag acagatgtaa caggttacca tgtaattccc tcttaccgag
    37741 aatttatcag cagtttcgaa gaaagggcag acgctcaaga cttgctgttc gttacagggt
    37801 ctctctattt tatctcagaa gtacggggct acctgctgga ccgtgagcag ataaattgac
    37861 cccctttttt gaacttgtta tactagggga attgctggtt agagaaaatt tctctaaatt
    37921 ggtagcagaa aggaaattca tcatgaaatt aaaaagattc acactttctc ttgcttctct
    37981 agcaagtttt agtctcttag tagcttgttc acaaagagct caacaggttc aacagcctgt
    38041 tgctcagcag gtccaacagc ctgctcaaca gaataccaat actgcaaatg caggaggtaa
    38101 ccaaaatcaa gcggctccag tacaaaacca acctgttgct caaccgaccg atattgatgg
    38161 gacttatact ggtcaggatg acggagaccg tatcacttta gtggtaactg gaacgactgg
    38221 tacatggact gagctcgaat ctgacgggga tcagaaagtc aaacaggtta catttgattc
    38281 agcaaatcaa cgcatgatta ttggcgatga tgtcaaaatt tacactgtaa acggtaatca
    38341 aatcgtcgta gatgatatgg atagagaccc atcggaccaa atcgttttaa ctaaataaga
    38401 ctatgcaagt agaaagggct ggatttttca gcctttttac ttttacctag aaaataatca
    38461 taaatacttg ccttctaccg aatacctgcg ttatactagt atcaattact tgtttttagc
    38521 attcaaacta tcaaggaggg gatatgaaat ataggaaatt tcaattattg atgtccaagt
    38581 atggctttag tctttcgatt atgctacttg aactttgtct tgtttttggt ctctttcttt
    38641 atttaggacg catggctccc attttatgga ttactgtcct cattctactg agtatcatca
    38701 caatcatttc gatagtcaac cgtaatacga ctcctgagaa taaggtaacc tggttgttag
    38761 tagcctttgt gccagtattt ggtcccttgc tctatctgat gtttggtgaa aggcgattgt
    38821 ccaaaaaaga aatcaaacaa ctgaagaagc taggctctat gcatttccaa gaagcaaata
    38881 gccagctact aaaagagaaa ttaaaagaaa gtgacaaggc agcttatgga gtcatcaagt
    38941 ccttattgag tatggatacc aatgctgaca tctatgatca aactgcctct acattttttc
    39001 ctaacggaga agctatgtgg aaaaagatgg tagaagatct taaaaaggct gagaaattta
    39061 ttttcttgga atattacatt atagaagaag gtttgatgtg gaatcgcata ctagatatac
    39121 tagagcaaaa ggtagctcag ggtgtagagg ttaagatgct ctatgatgat atcggctgta
    39181 tggctacttt aacaggagat tatgcacatc gacttcgtca gctgggcatc gaggcccata
    39241 aattcaataa agttattcct cgtttgacag tggcttataa taacagagat catagaaaaa
    39301 tattgattgt tgatggtcag atagcctata ctggtggggt caatctggca gatgagtaca
    39361 ttaaccacgt cgagagattt ggttattgga aggatagtgg aattcgctta gacggactag
    39421 cagtaaaagc cctgacacgc ttatttttga ccacttggta cattaatcga ggagaaatta
    39481 gtgattttga tcaatatcat ttagaaaatc attctatccc gagtgacggt ttaaccattc
    39541 catacggaag tggacccaag ccaatttttc gagcgcaggt agggaaaaaa gtttatcaga
    39601 gtttaatcaa tcaagcaaca gaatcggtct atattacgac accttatttg attatagatt
    39661 atgatttaac agagacaatc aaaaatgcag ctatgagagg ggtcgatgtt cgaattatca
    39721 ccccttacat accagataag aagttcattc agttagtcac gagaggagct tatcccgacc
    39781 ttctttctgc tggtgttcgg atttatgagt atagtccagg ttttattcat agtaagcaga
    39841 tgttggtaga cgaagatttt gcggtggtgg ggacaatcaa tctcgactac cggagcttgg
    39901 tacaccatta tgaaaatgca gtcttactct ataaaactcc ttctataagg gaaatcgccc
    39961 gagattttcg aaatatattt gcagattctc aggaagtcta tcctcattct atcaaaacga
    40021 gctggtatca aaagcttgta aaagaaatcg cccagctatt cgcccctatc ttataagaaa
    40081 tctagaactt aggatacaaa ccagacctat ttttcttgtc ttttactaat agaaagaaag
    40141 aggaggggaa ttcatgctaa ctaaggaaga agtgaatgat atgattgagt tcaaacagac
    40201 acatttatac cgctttcggg aaattgaaac ctttgtgaaa ctatgcaaaa aatcactcaa
    40261 acagccatcg caagctgaca atcctaggac tttttgatat actaagacag ataaattgaa
    40321 caggagaaac gatatgagtg tgtatggtag agtagaagaa gttcataagg agaatcgtga
    40381 acctctagaa taccaaatcg aacaagaatc gcatcatcgt gaatcaagtc gtcttccttt
    40441 ggtgaaaatt ttactatgga gtacgcttgt aacggggata actctaggag taccgctatt
    40501 actcgactta atgagtgcac aagaagtgca ggatttttat gcaggttggg ggcttcatca
    40561 gacagggaag atttacagcg actattatgg aagtcaaggt ttgctttatt atttgctgac
    40621 ttacgtgagt cagggcggat ttttctttgc catctttgag tggttagcct tggtagcagg
    40681 aggatttttc ctttttagat cagcggacac cttgacagag caaggagacc aagctggaca
    40741 tctggtgact attttttaca tgctagttac aggtcttgct tttggtggag gctatgcgac
    40801 tcttttagcg cttcctttct tattcgcagc ctttagttta gttgcggctt acctaagcaa
    40861 tccaagccat gataagggat ttgtacggat tgggctagct ttggcaggcg gatttttctt
    40921 tgctccctta tcatcgctcc tgtttattgc tgtagtgagt ttaggcttgt tggtctttaa
    40981 ccttgggcat agacgctttg cgcatgggtt ttatcagttt cttgcagtgg ctttaggttt
    41041 ttcacttgtc ttttatccaa ctgcctacta tagtgctgca acaggaagtt ttggggatgc
    41101 gattagtggt attcgttatc ctattgacag tattcgcttt gattttactt ctaaaatttt
    41161 agagaatatg tttttttatg gcttgttgtc ccttggtttg ggatttgtgg tttgtatctt
    41221 tttaggtctc tttcaatcca aaccctttaa actatacgtc atttcggttc ctgcaagtct
    41281 tgtggtaatt ttaggtttga ttttactttt cttttcacaa gagcctctgc acgcttctta
    41341 tttgatggtc gtcttccctg ttttcctact tttattggta accaatatta agagtcaaca
    41401 gagggggcgt agtgctagaa gaagccgaag agaaacgcca gttagcctat ggagtcgttt
    41461 cttcaaagga aatctatatc tgctagtttt tgggtttgtc tatcttttgt ctgttccttt
    41521 tttgatgaag tttgtccttt atccagtacc ttatcaagaa cgtaatcgtc ttgctgattt
    41581 ggtaaaagag gagacaaata cggaagatgc tatctatgca tgggatgata ctgcgactct
    41641 ttatcgtaag agtgagcgct tgtcgccatc ggcgattttg tccccgttgc actatacagc
    41701 aactgaggaa aatcgtaata agttacttaa tgacttgaaa gaaaaacaac ctaaggtgat
    41761 tgtggtaaat gacaaggtgg tagtctggtc tgaagtggaa acacttttaa aagaaaatta
    41821 ccaacaagta aagactgatt actcagagtt taaagtctat aaaattaaat aaccaaatca
    41881 atatcttgtg tatttttaaa aattttagga tttttaacac aagatattga tttttctttt
    41941 tagagtggta taatactttt tagaaagaac attttagaaa agagcatgcg tatgattgca
    42001 ctagaagaaa aaattacaat tttgccaact ctcttcgtcg agaaacgaga tgggagacgt
    42061 gttgtatttg atgtggacaa gattgacaag gctctccaca aggcggctga caaggttatg
    42121 gatgtgacac ccctggttga aaaacgcctc aatgatctga ctgagcgaat tattacagaa
    42181 attcatagtc gctttccaca gggaattaag atttacgaaa ttcaaaatat cgtagaacat
    42241 gaactccttg aagccaaaga atatgcgctg gctgaggagt atattactta tcggacacag
    42301 agggattttg agcgctcaaa agcgacggat atcaacttta gtattcataa acttctcaac
    42361 aaagaccaga cagttgtcaa tgaaaatgct aataaagaca gtgatgtctt taacactcag
    42421 cgtgatttga cagcagggat tgttgggaaa tcaatcggac tgcaaatgct tcctaagcac
    42481 gtagccaatg cccaccaaaa gggggatatc cactatcacg atttggacta cagtccctat
    42541 acccctatga ccaactgctg tttgattgat tttaagggta tgttggaaaa tggttttaag
    42601 attggaaatg cagaggtaga gagtcccaag tctatccaga ctgcgacagc acagatttct
    42661 caaatcattg ccaacgttgc ttctagccag tacggtggct gttcagctga ccgtatcgat
    42721 gaaattttgg cgccttatgc agagaagaat tatcaaaaac atctcaaaga tgcagaagag
    42781 tgggtattgc ctgaaaaacg ggaagattac gcttggaaga aaacgcaaaa ggacatctac
    42841 gatgccatgc aatctcttga gtatgaaatc aatactctct tcacttcaaa tggacaaaca
    42901 ccttttactt cgttaggttt tggtctggga accagtcgtt ttgaacgaga aattcaaaaa
    42961 gctattttaa acattcgcat caagggtctt ggttcagaac accgtacggc tatctttcct
    43021 aaacttattt tcactctgaa aagaggcctt aatttagagg aaggaactcc caactacgac
    43081 atcaagcagt tggctcttga gtgtgcaacc aaacggatgt atccagatgt tttatcttac
    43141 gataagattg ttgacttgac aggatccttc aaggtgccta tgggttgccg ttctttcctc
    43201 caaggatgga aggatgaaaa tggtgtagaa gtcaattcag gtcgcatgaa tctgggtgtt
    43261 gtgacggtta atctgcctcg tattgctctt gagtctgaag gtgatatgaa taagttctgg
    43321 gaaatcttca acgagcgaat gaatatcgca gaagatgctc ttgtttaccg tgtcgaacgc
    43381 actaaagagg cgacaccagc aaatgctcct attctttatc agtacggtgc ttttggccat
    43441 cgtctaggta aagaagaaag tgttgaccag ctctttaaga atcgtcgtgc taccgtttcg
    43501 ctgggctata tcggcttgta tgaagtagcg acagttttct ttggtaacag ctgggaaagt
    43561 aatccagatg ctaaggaatt cacgctagac atcattcacg atatgaaacg ccgtgtagaa
    43621 gagtggtcag accaatatgg ctaccatttc tctatctact caacaccatc cgaaagtctg
    43681 acagaccgtt tctgtcgact agatatagac aagtttggct ctattcctga tatcacagac
    43741 aaggaatact acaccaactc tttccactac gatgttcgta aaaatccaac accgtttgaa
    43801 aaattggact ttgagaaagt ctatccagaa gcaggtgcgt caggtggttt catccattat
    43861 tgtgagtatc cagtccttca gcaaaatcca aaggccttgg aagctgtctg ggattatgct
    43921 tatgaccgtg taggctatct aggcaccaat actccgattg accgttgcta caagtgtgac
    43981 tttgaagggg attttgaacc aactgagaga gggtttgctt gtccaaactg tggcaatagc
    44041 gaccctaaaa cagtagatgt ggtgaagcga acttgtggct acctaggtaa tcctcaagca
    44101 agaccgatgg tcaacggccg tcacaaggaa atcgctgcgc gtgtcaaaca tatgaatggt
    44161 tcaacgatta aaatagctgg gcatcaagta acaaattaga aagaaatgaa atgggaaaat
    44221 atcaactaga cgataagggg cgcgcacaag tgacccgtta tcacgagaaa cactctaaag
    44281 gtggagctgg taagaaagaa cgcttgctta gcttcagaga acaattttta aacaagaaca
    44341 agaaaaaata aaagtgagag ccagctctcg cttttctcat agtgggaggt aaggatggaa
    44401 ttacgcagac caagattagc ggataagaaa gctgttttag atatgatgac agagtttgaa
    44461 aaatttcagt cgcctcacga cggcggtttc tgggatacag agaactttgt gtatgaagac
    44521 tggttagaaa gcaatcagga acaggaaatg gggattaatc tgcctgaagg atgggttcct
    44581 gcaattcagt tagtggcttt ttctgagaaa ggtcaagcag ttggatttct taatctccgg
    44641 ttgcgcctca gtaactttct actagaagaa ggtggccaca ttggctactc cattcgtcca
    44701 tctgaaagag gcaagggtta tgcaaaagag actctccgtc agggcttgca agttgctaag
    44761 gaaaagaaca tcaagaaagc tctggtgacc tgtagcgtga ataatcctgc tagcagagca
    44821 gtcattctag caaatggtgg aatatttgag gatgctcgca atggagtcga gcgttattgg
    44881 atagaggtag cgaatgaata atccaaaacc acaagaatgg aaaagcgagg aacttagtca
    44941 aggtcgtatc attgactaca aggcctttaa ctttgtggac ggcgaaggcg tgcgtaactc
    45001 tctctatgta tcaggctgta tgtttcactg cgagggatgt tataatgttg caacttggtc
    45061 ttttaatgct ggcattccct atacagcaga attagaagag cagatcatgg cagatcttgc
    45121 tcagccctat gttcaaggtt tgactttgtt gggaggggag ccttttctta atactgggat
    45181 tctcttgcca cttgttaagc ggattcggaa ggaattgcca gacaaggaca tctggtcctg
    45241 gaccggctac acttgggaag aaatgatgtt ggaaactcca gataaactgg aattcttgtc
    45301 actgattgac attcttgtcg atggaagata tgatcgaact aagagaaatc ttatgctcca
    45361 gtttcgaggt tcatctaacc aacgaattat cgatgtgcaa aaatcgctca aaagtgggca
    45421 agtagtgatt tgggacaagc tcaatgacgg aaaagaaagc tatgaacagg tgaagagaga
    45481 atgaagaaaa aatgaagaaa aaagacttag tagaccaact agtctcagag atcgagacgg
    45541 ggaaagtcag gacactggga atatacggtc atggagcttc aggtaaatca acctttgcac
    45601 aggaattgta ccaagcttta gattctacta cagtaaattt gctagaaaca gatccctata
    45661 tcacctccgg acgctatttg gtagtaccca aggacgcgcc gaatcaaaag gtgacagcca
    45721 gtctgccagt ggcgcatgaa ctggagagtt tgcagagaga tatccttgcc ttgcaggcgg
    45781 gtatggatgt cttgacaatt gaagaacctt ggaaggctag tgaggtcttg tctggagcca
    45841 aaccaatttt gattgtcgaa gggatgtctg ttggttttct acccaaggaa ctctttgaaa
    45901 aaaccatctg tttctacacg gatgaggaga ccgaattaaa gcgacgcctt gctagagata
    45961 cgactgtgag aaatcgctat gcatccttta tattggctag ccatcagatg agacgggagc
    46021 agtatctgcg atactataaa gaaactgagt ctaaggcgga tatcttagtg gaccaatcag
    46081 aagataaatt tgatgtcaag aggacttaac ttatgtatag aagaaatata gaagaaaatc
    46141 cctaatttta gaaagaaaaa gtaggaaaac agtttcatcc caaaaaaacg aaaaaaccta
    46201 acaaatccct tgcaatcgca ggggatttgt gttattctat tatggtgctg taaattacag
    46261 ccttagtttt gatgcaagag gttgcgacac gctcggttgc attgccacgc aacaccgcgt
    46321 cggttttctt gtggagctag cctattatct taaatagacg aaaaggagaa aaagatggca
    46381 aacaaaaaaa tccgtatccg tttgaaagct tacgaacacc gtacgcttga cacagcggct
    46441 gcaaaaatcg tagaatcagc tactcgtaca ggtgcacaag ttgcgggtcc aatcccactt
    46501 ccaactgaac gtagcctcta cacaatcatt cgtgcgactc acaaatacaa agactctcgc
    46561 gaacaatttg aaatgcgtac acacaaacgt ttgatcgata tcgttaaccc aactcaaaaa
    46621 acagttgatg ccttgatgaa attggatctt ccaagtggtg taaacgtaga aatcaaactt
    46681 taatctaaaa tataaaagag cagaggctgg tgtttcaatc taattgaaca cgggctaaac
    46741 tcggtgtgaa aaagataaac ttcctcgcgt ctgctagaca ctgtgtcagt ttcctatttt
    46801 cactttgagt ttgacgccct ttgtatctta gacttgagca taaaaaacgc tcgttaaaaa
    46861 ctttttgaat aaaaaatata gaaaaggaac tattttctca tgacaaaagg aatcttaggg
    46921 aaaaaagtgg gaatgactca aatcttcact gaagctggcg aattgatccc tgtaacagtt
    46981 attgaagcaa ctccaaacgt tgttcttcaa gttaaaactg ttgaaacaga cggatacaac
    47041 gctatccaag ttggtttcga tgacaaacgc gaagtattga gcaacaaacc tgctaaagga
    47101 catgtagcga aagctaacac ggctcctaag cgcttcattc gtgaattcaa aaacgttgaa
    47161 ggcttggaag ttggtgctga aattacagtt gaaacattcg cagctggaga cgttgttgac
    47221 gtaactggta cttctaaagg taaaggtttc caaggtgtta tcaaacgcca cggacaatca
    47281 cgtggaccaa tggctcacgg ttctcgttac caccgtcgtc caggttctat gggacctgtt
    47341 gcacctaacc gcgtattcaa aggtaaaaac cttgcagggc gtatgggtgg cgaccgcgta
    47401 acaattcaaa accttgaagt tgtacaagtt gttccagaaa agaacgttat ccttatcaaa
    47461 ggtaacgtac caggtgctaa gaaatctctt atcactatca aatcagcagt taaagctggt
    47521 aaataataaa gaaaggggaa atcagtcaca atggcaaacg taacattatt tgaccaaact
    47581 ggtaaagaag ctggccaagt tgttcttagc gatgcagtat ttggtatcga accaaatgaa
    47641 tcagttgtgt ttgatgtaat catcagccaa cgcgcaagcc ttcgtcaagg aacacacgct
    47701 gttaaaaacc gctctgcagt atcaggtggt ggacgcaaac catggcgtca aaaaggaact
    47761 ggacgtgctc gtcaaggttc tatccgctca ccacaatggc gtggtggtgg tgttgtcttc
    47821 ggaccaactc cacgttcata cggctacaaa cttccacaaa aagttcgtcg cctagctctt
    47881 aaatcagttt actctgaaaa agttgctgaa aacaaattcg tagctgtaga cgctctttca
    47941 tttacagctc caaaaactgc tgaatttgca aaagttcttg cagcattgag catcgattct
    48001 aaagttcttg ttatccttga agaaggaaat gaattcgcag ctctttcagc tcgtaacctt
    48061 ccaaacgtga aagttgcaac tgctacaact gcaagtgttc ttgacatcgc aaatagcgac
    48121 aaacttcttg tcacacaagc agctatctct aaaatcgagg aggttcttgc ataatgaatt
    48181 tgtatgatgt tatcaaaaaa cctgtcatca ctgaaagctc aatggctcaa cttgaagcag
    48241 ggaaatatgt atttgaagtt gacactcgtg cacacaaact tttgatcaag caagctgttg
    48301 aagctgcttt cgaaggtgtt aaagttgcca atgttaacac aatcaacgta aaaccaaaag
    48361 ctaaacgtgt tggacgttac actggtttta ctaacaaaac taaaaaagct atcatcacac
    48421 ttacagctga ttctaaagca atcgagttgt ttgctgctga agctgaataa tctaaggagg
    48481 aaatatcgtg ggaattcgtg tttataaacc aacaacaaac ggtcgccgta atatgacttc
    48541 tttggatttc gctgaaatca caacaagcac tcctgaaaaa tcattgcttg ttgcattgaa
    48601 gagcaaggct ggtcgtaaca acaacggtcg tatcacagtt cgtcaccaag gtggtggaca
    48661 caaacgtttt taccgtttgg ttgacttcaa acgtaataaa gacaacgttg aagcagttgt
    48721 taaaacaatc gagtacgatc caaaccgttc tgcaaacatc gctcttgtac actacactga
    48781 cggtgtgaaa gcatacatca tcgctccaaa aggtcttgaa gtaggtcaac gtatcgtttc
    48841 aggtccagaa gcagatatca aagtcggaaa cgctcttcca cttgctaaca tcccagttgg
    48901 tactttgatt cacaacatcg agttgaaacc aggtcgtggt ggtgaattgg tacgtgctgc
    48961 tggtgcatct gctcaagtat tgggttctga aggtaaatat gttcttgttc gtcttcaatc
    49021 aggtgaagtt cgtatgattc ttggaacttg ccgtgctaca gttggtgttg tcggaaacga
    49081 acaacatgga cttgtaaacc ttggtaaagc aggacgtagc cgttggaaag gtatccgccc
    49141 aacagttcgt ggttctgtaa tgaaccctaa cgatcaccca cacggtggtg gtgaaggtaa
    49201 agcaccagtt ggtcgtaaag caccatctac tccatggggc aaacctgctc ttggtcttaa
    49261 aactcgtaac aagaaagcga aatctgacaa acttatcgtt cgtcgtcgca acgagaaata
    49321 atattaaact agtcgcttaa gcaactagta aatccgccag ctcggtagcg ctccatagga
    49381 gtgcaagccg ctgtggtaca acatttaaag gagaaaatat aaaaatggga cgcagtctta
    49441 aaaaaggacc tttcgtcgat gagcatttga tgaaaaaagt tgaagctcaa gctaacgacg
    49501 aaaagaaaaa agttattaaa acttggtcac gtcgttcaac gatcttccca agtttcattg
    49561 gttacactat tgcagtttat gacggacgta aacacgtacc tgtttacatc caagaagaca
    49621 tggtaggcca caaacttggt gaatttgcac caactcgtac ttacaaaggt cacgctgcag
    49681 acgacaagaa aacacgtaga aaataaggag aacataaatg gcagaaatta cttcagctaa
    49741 agcaatggct cgtacagtac gtgtttcacc tcgtaaatca cgtcttgttc ttgataacat
    49801 ccgtggtaaa agcgtagccg atgcaatcgc aatcttgaca ttcactccaa acaaagctgc
    49861 tgaaatcatc ttgaaagttt tgaactcagc tgtagctaac gctgaaaaca actttggttt
    49921 ggataaagct aatttggtag tatctgaagc attcgcaaac gaaggaccaa ctatgaaacg
    49981 tttccgtcca cgtgcgaaag gttcagcttc accaatcaac aaacgtacag ctcacatcac
    50041 tgtagctgtt gcagaaaaat aaggaggtaa aatcgtgggt caaaaagtac atccaattgg
    50101 tatgcgtgtc ggcatcatcc gtgattggga tgccaaatgg tatgctgaaa aagaatacgc
    50161 ggattacctt catgaagatc ttgcaatccg taaattcgtt caaaaagaac ttgctgacgc
    50221 agcagtttca actattgaaa tcgaacgcgc agtaaacaaa gttaacgttt cacttcacac
    50281 tgctaaacca ggtatggtta tcggtaaagg tggtgctaac gttgatgcac tccgtgcaaa
    50341 acttaacaaa ttgactggaa aacaagtaca catcaacatc atcgaaatca aacaacctga
    50401 tttggatgct caccttgtag gtgaaggaat tgctcgtcaa ttggagcaac gtgttgcttt
    50461 ccgtcgtgca caaaaacaag caatccaacg tgcaatgcgt gctggagcta aaggaatcaa
    50521 aactcaagta tcaggtcgtt tgaacggtgc agatatcgcc cgtgctgaag gatactctga
    50581 aggaactgtt ccgcttcaca cacttcgtgc agatatcgat tacgcttggg aagaagcaga
    50641 tactacatac ggtaaacttg gtgttaaagt atggatctac cgtggtgaag ttcttccagc
    50701 tcgtaaaaac actaaaggag gtaaataacc aatgttagta cctaaacgtg ttaaacaccg
    50761 tcgtgagttc cgtggaaaaa tgcgcggtga agcaaaaggt ggaaaagaag tagcattcgg
    50821 tgaatacggt cttcaagcta caactagcca ctggatcact aaccgccaaa tcgaagctgc
    50881 tcgtatcgcc atgactcgtt acatgaaacg tggtggtaaa gtttggatta aaatcttccc
    50941 acacaaatca tacactgcta aagctatcgg tgtgcgtatg ggatctggta aaggggcacc
    51001 tgaaggttgg gtagcaccag ttaaacgtgg taaagtgatg ttcgaaatcg ctggtgtatc
    51061 tgaagagatt gcacgtgaag cgcttcgact tgctagccac aaattgccag ttaaatgtaa
    51121 attcgtaaaa cgtgaagcag aataaggaga aggcatgaaa cttaatgaag taaaagaatt
    51181 tgttaaagaa cttcgtggtc tttctcaaga agaactcgcg aagcgcgaaa acgaattgaa
    51241 aaaagaattg tttgaacttc gtttccaagc tgctactggt caattggaac aaacagctcg
    51301 cttgaaagaa gttaaaaaac aaatcgctcg tatcaaaaca gttcaatctg aagcgaaata
    51361 atagactagg gaaggagaaa tttcaatgga acgcaataat cgtaaagttc ttgttggacg
    51421 tgttgtatct gacaaaatgg acaagacaat cacagttgta gttgaaacaa aacgtaacca
    51481 cccagtctat ggtaaacgta ttaactactc taaaaaatac aaagctcatg atgaaaacaa
    51541 tgttgccaaa gaaggcgata tcgtacgtat catggaaact cgcccgcttt cagctacaaa
    51601 acgtttccgt cttgtagaag ttgttgaaga agcggtcatc atctaatcaa acctgaaagg
    51661 agaaaactga aatgattcaa acagaaactc gtttgaaagt cgcagacaac agcggtgctc
    51721 gcgaaatctt gactatcaaa gttcttggtg gttcaggacg taaatttgca aacatcggtg
    51781 atgttatcgt ggcatctgta aaacaagcta ctcctggtgg tgcggttaaa aaaggtgacg
    51841 ttgttaaagc agttatcgtt cgtactaaat caggtgctcg tcgtgctgat ggttcataca
    51901 tcaaatttga cgaaaacgca gcagttatca tccgtgaaga caaaactcct cgcggaacac
    51961 gtatctttgg cccagttgca cgtgaattgc gtgaaggtgg cttcatgaag atcgtgtcac
    52021 ttgctccaga agtactttaa tttttaggaa caaactagtc ccctagcttc aagctagggt
    52081 gcccttatgg gcgtaagaaa aatcaaggag aaacctaatg tttgtaaaaa aaggcgacaa
    52141 agttcgcgta atcgctggta aagataaggg aacagaagct gttgtcctta ctgcccttcc
    52201 aaaagtaaac aaagttatcg ttgaaggtgt taacattgtt aagaaacacc aacgtccaac
    52261 taacgagctt cctcaaggtg gtatcatcga gaaagaagca gctatccacg tatcaaacgt
    52321 tcaagttttg gacaaaaatg gtgtagctgg tcgtgttggt tacaaatttg tagacggtaa
    52381 aaaagttcgc tacaacaaaa aatcaggcga agtgcttgat taatcacgaa ggaaaggaga
    52441 agtataatgg caaatcgttt aaaagaaaaa tatcttaatg aagtagttcc tgctttgaca
    52501 gaacaattca actactcatc agtgatggct gtgcctaaag tagataagat tgttttgaac
    52561 atgggtgttg gtgaagctgt atcaaacgct aaaagccttg aaaaagctgc tgaagaattg
    52621 gcacttatct caggtcaaaa accacttatc actaaagcta aaaaatcaat cgccggcttc
    52681 cgtcttcgtg aaggtgttgc gatcggtgca aaagttaccc ttcgtggtga acgtatgtac
    52741 gaattcttgg ataaattggt atcagtttca cttccacgtg tacgtgactt ccacggtgtt
    52801 ccaacaaaat catttgatgg acgcgggaac tacacacttg gtgtgaaaga acaattaatc
    52861 ttcccagaaa tcaacttcga tgacgttgac aaaactcgtg gtcttgacat cgttatcgta
    52921 acaactgcta acactgacga agagtcacgt gcattgctta caggccttgg aatgcctttt
    52981 gcaaaataat ataggaggta aatctaatgg ctaaaaaatc aatggtagct agagaggcta
    53041 aacgccaaaa aattgttgac cgttatgctg aaaaacgtgc tgcattaaag gcggcagggg
    53101 actacgaagg tttatctaaa ttacctcgca acgcttcacc gactcgttta cataatcgtt
    53161 gtagagttac ggggcgccca cattcagttt accgcaaatt tggtctgagt cgtatcgctt
    53221 ttcgcgaact tgcgcataaa ggtcaaattc ctggtgtaac aaaagcatct tggtaattta
    53281 agatatcaag ggcgtcaaaa ctccaagtaa aaataggaaa cttgacgaag aaactaaagt
    53341 ttctaggaaa gtttatcttt ttcacacaga gtttagcccg ggttcaattg ggcttgccaa
    53401 tttgaacacg agctacagct ttggcaaaaa agaccaattt gctttggagc attgcttctg
    53461 cattaaattg tctatttttg ctcgtgctgt tacgctcttt gtatcatgta ttaactagca
    53521 agtgcaactt gcaaactact agtaagagga gaaaaacaaa atggttatga ctgacccaat
    53581 cgcagacttc ctaactcgta ttcgtaatgc taaccaagct aaacacgaag tacttgaagt
    53641 acctgcatca aacatcaaaa aagggattgc tgaaatcctt aaacgcgaag gttttgtaaa
    53701 aaacgttgaa atcatcgaag atgacaaaca aggcgtcatc cgtgtatttc ttaaatacgg
    53761 accaaatggt gaaaaagtta tcactaactt gaaacgtgtt tctaaaccag gacttcgtgt
    53821 ctacaaaaaa cgtgaagacc ttccaaaagt tcttaacgga cttggaattg ccatcctttc
    53881 aacttctgaa ggtttgctta ctgataaaga agcacgccaa aagaatgttg gtggtgaggt
    53941 tatcgcttac gtttggtaaa atcaagatac aaagctcgta aagaacaaag caaaattagg
    54001 aagttggaga agtttgttta caaacaagcc aacttatcta ttttgcacag ttcttagagc
    54061 gtgttcagtt cagctcttga actaaataag tatctgaacc ccgtgaaaac tggccgtttt
    54121 ggcctgacaa tttaacagga gaaaataaac atgtcacgta ttggtaataa agttatcgtg
    54181 ttgcctgctg gtgttgaact cgctaacaat gacaacgttg taactgtaaa aggacctaaa
    54241 ggagaactta ctcgtgagtt ctcaaaagat attgaaatcc gtgtggaagg tactgaagta
    54301 actcttcacc gtccaaacga ttcaaaagaa atgaaaacta tccacggaac tactcgtgcc
    54361 cttttgaaca acatggttgt tggtgtatca gaaggattca agaaagaact tgaaatgcgt
    54421 ggggttggtt accgtgcaca gcttcaagga tctaaacttg ttttggctgt tggtaaatct
    54481 catccagacg aagttgaagc tccagaagga attacttttg aacttccaaa cccaacaaca
    54541 atcgttgtta gcggaatttc aaaagaagta gttggtcaaa cagctgctta cgtacgtagc
    54601 cttcgttcac cagaaccata taaaggtaaa ggtatccgtt acgttggtga attcgttcgc
    54661 cgtaaagaag gtaaaacagg taaataatgt tgagtggttg atcatcaacc accaacctat
    54721 tttccaactt tgtgcatagc acacgattta aaactaaaga ggtgaaaact gtgatttcaa
    54781 aaccagataa aaacaaactc cgccaaaaac gccaccgtcg cgttcgcgga aaactctctg
    54841 gaactgctga tcgcccacgt ttgaacgtat tccgttctaa tacaggcatc tacgctcaag
    54901 tgattgatga cgtagcgggt gtaacgctcg caagtgcttc aactcttgat aaagaagttt
    54961 caaaaggaac taaaactgaa caagccgttg ctgtcggtaa actcgttgca gaacgtgcaa
    55021 acgctaaagg tatttcagaa gtggtgttcg accgcggtgg atatctatat cacggacgtg
    55081 tgaaagcttt ggctgatgca gctcgtgaaa acggattgaa attctaatag gaggacacta
    55141 gaaaatggca tttaaagaca atgcagttga attagaagaa cgcgtagttg ctgtcaaccg
    55201 tgttacaaaa gttgttaaag gtggacgtcg tcttcgtttc gcagctcttg ttgttgttgg
    55261 tgaccacaat ggtcgcgtag gatttggtac tggtaaagct caagaagttc cagaagcaat
    55321 ccgtaaagca gtagatgatg ctaagaaaaa cttgatcgaa gttcctatgg ttggaacaac
    55381 aatcccacac gaagttcttt cagaattcgg tggagctaaa gtattgttga aacctgctgt
    55441 agaaggttct ggagttgccg ctggtggtgc agttcgtgcc gttgtggaat tggcaggtgt
    55501 ggcagatatt acatctaaat cacttggttc taacactcca atcaacattg ttcgtgcaac
    55561 tgttgaaggt ttgaaacaat tgaaacgcgc tgaagaaatt gctgcccttc gtggtatttc
    55621 agtttctgat ttggcataag aaaggggata aaatggctca aattaaaatt actttgacta
    55681 agtctccaat cggacgcatt ccatcacaac gtaaaactgt tgtagcactt ggacttggca
    55741 aattgaacag ctctgttatt aaagaagata acgctgctat ccgtggtatg attacagcag
    55801 tatctcactt agtaacagtt gaagaagtaa actaatgaag ttttagggga tgtgcactgt
    55861 accatcccct aaaactagat atagtcatct atgatgacat cgtataggcg agttgatggg
    55921 ggagacaacc ttttctccct tatcggcgct agcattttac aaaagaggag aaaataaaaa
    55981 tgaaacttca tgaattgaaa cctgcagaag gttctcgtaa agtacgtaac cgcgttggtc
    56041 gtggtacttc atcaggtaac ggtaaaacat ctggtcgtgg tcaaaaaggt caaaaagctc
    56101 gtagcggtgg cggagttcgc cttggttttg aaggtggaca aactccattg ttccgtcgtc
    56161 ttccaaaacg tggattcact aacatcaacg ctaaagaata cgcaattgtg aaccttgacc
    56221 aattgaacgt ctttgaagat ggtgctgaag taactccagt tgttcttatc gaagcaggaa
    56281 ttgttaaagc tgaaaagtca ggtattaaaa ttcttggtaa cggtgagttg actaagaaat
    56341 tgactgtgaa agcagctaaa ttctctaaat cagctgaaga agctatcact gctaaaggtg
    56401 gttcagtaga agtcatctaa gagaggtgac ctatgttttt taaattatta agagaagctc
    56461 ttaaagtcaa gcaggttcga tcaaaaattt tatttacaat ttttatcgtt ttggtctttc
    56521 gtatcggaac tagcattaca gttcctggtg tgaatgccaa tagcttgaat gctttaagtg
    56581 gattatcctt cttaaacatg ttgagcttgg tgtcggggaa tgccctaaaa aacttttcga
    56641 tttttgccct aggagttagt ccctatatca ccgcttctat tgttgtccaa ctcttgcaaa
    56701 tggatatttt acccaagttt gtagagtggg gtaaacaagg ggaagtaggt cgaagaaaat
    56761 tgaatcaagc tactcgttat attgctctag ttctcgcttt tgtgcaatct atcgggatta
    56821 cagctggttt taataccttg gctggagctc aattgattaa aactgcttta actccacaag
    56881 tttttctgac gattggtatc atcttaacag ctggtagtat gattgtcact tggttgggtg
    56941 agcaaattac agataaggga tacggaaacg gtgtttccat gattatcttt gccgggattg
    57001 tttcctcaat tccagagatg attcagggca tctatgtgga ctactttgtg aacgtcccaa
    57061 gtagccgtat cacttcatct atcattttcg taatcatttt gattattact gtattgttga
    57121 ttatttactt tacaacttat gttcaacaag cagaatacaa aattccaatc caatatacta
    57181 aggttgcaca aggtgctcca tctagctctt accttccgtt aaaggtaaac cctgctggag
    57241 ttatccctgt tatctttgcc agttcgatta ctgcagcgcc tgcggctatt cttcagtttt
    57301 tgagtgccac aggtcatgat tgggcttggg taagggtagc acaagagatg ttggcaacta
    57361 cttctccaac tggtattgcc atgtatgctt tgttgattat tctctttaca ttcttctata
    57421 cgtttgtaca gattaatcct gaaaaagcag cagagagcct acaaaagagt ggtgcctata
    57481 tccatggagt tcgtcctggt aaaggtacag aagaatatat gtctaaactt cttcgtcgtc
    57541 ttgcaactgt tggttccctc ttccttggtg tgatttccat tttaccgatt gcagctaaag
    57601 atgtatttgg tctttctgat gttgttgcct ttggtggaac aagtctcttg atcattatct
    57661 ctacaggtat cgaaggaatc aagcaattgg aaggttacct attgaaacgt aagtatgttg
    57721 gtttcatgga cagaacagaa taaaagtatt tactgaatca gtaaatactg agggagtgga
    57781 ggtttaaact ctgacatttg taagagttgg atctcccctc ttctattttg tttttaaata
    57841 ggggtgaaaa gactttttgc ttctatttaa aaataaaata aggagatcaa atcatgaatc
    57901 ttttgattat gggcttacct ggtgcaggta agggaactca agcagcaaaa atcgtagaac
    57961 aattccatgt tgcacatatc tcaacaggtg atatgttccg cgctgcaatg gcaaatcaaa
    58021 ctgaaatggg tgttcttgct aagtcatata ttgacaaggg tgaattggtt cctgacgaag
    58081 ttacaaatgg aatcgtaaaa gaacgccttt cacaagatga tattaaagaa acaggattct
    58141 tattggatgg ttacccacgt acaattgaac aagctcatgc cttggacaaa acattggctg
    58201 aacttggcat tgaactagaa ggtattatca atattgaagt gaaccctgac agcctcttgg
    58261 aacgtttgag tggccgtatc atccaccgcg taactggaga aactttccac aaggtcttta
    58321 acccaccagt tgactataaa gaagaagatt actaccaacg tgaagatgat aagcctgaga
    58381 cagtaaaacg tcgtttggat gttaatattg ctcaaggaga accaatcatt gctcactacc
    58441 gtgccaaagg tttggttcat gacatcgaag gtaatcaaga tatcaatgat gtcttctcag
    58501 atattgaaaa agtattgaca aatttgaaat aaagcgtttt tcgcacttgc aaaaatccgc
    58561 tacaaatgtt atactgagat agtctgactt ataattgttg tctctgtgtc tagaggcatc
    58621 gaatcgaaat ttatggaggt gcttttgcgt ggcaaaagac gatgtgattg aagttgaagg
    58681 caaagtagtt gatacaatgc cgaatgcaat gtttacggtt gaacttgaaa atggacatca
    58741 gattttagca acagtttctg gtaaaattcg taaaaactat attcgtattt tagcgggaga
    58801 tcgtgttact gtcgaaatga gtccatatga cttgacacgt ggacgtatca cttaccgctt
    58861 taaataatcg aaaaacttgg agggataaga aatgaaagta agaccatcgg tcaaaccaat
    58921 ttgcgaatac tgtaaagtta ttcgtcgtaa tggtcgtgtt atggtaattt gcccagcaaa
    58981 tccaaaacac aaacaacgtc aaggataaga tagaaaggag aaaacatggc tcgtattgct
    59041 ggagttgata ttccaaatga caaacgcgta gtaatctcat tgacttatgt ttatggtatc
    59101 ggacttgcaa catctaagaa aattttggct gctgctggaa tctcagaaga tgttcgtgta
    59161 cgtgatctta catcagatca agaagatgct atccgtcgtg aagtggatgc aatcaaagtt
    59221 gaaggtgacc ttcgtcgtga agtaaacttg aacatcaaac gtttgatgga aatcggttca
    59281 taccgtggta tccgtcaccg tcgtggactt cctgtccgtg gacaaaacac taaaaacaac
    59341 gctcgcactc gtaaaggtaa agctgttgcg attgctggta agaaaaaata atataggagg
    59401 taaaagtctt ggctaaacca acacgtaaac gtcgtgtgaa aaagaatatc gaatctggta
    59461 ttgctcatat tcacgctaca tttaataaca ctattgttat gattactgat gtgcatggta
    59521 atgcaattgc ttggtcatca gctggtgctc ttggtttcaa aggttctcgt aaatctacac
    59581 cattcgctgc tcaaatggct tctgaagctg ctgctaaatc tgcacaagaa cacggtctta
    59641 aatcagttga agttactgta aaaggtccag gttctggtcg tgagtcagct attcgtgcgc
    59701 ttgctgccgc tggtcttgaa gtaacagcaa ttcgtgatgt gactccagtg ccacacaatg
    59761 gtgctcgtcc tccaaaacgt cgccgtgtat aatcatcgca ttacactgct tttcgtttaa
    59821 gagggagtaa ctaaatgatc gagtttgaaa aaccaaatat aacaaaaatt gatgaaaata
    59881 aagattatgg caagtttgta atcgaaccac ttgaacgtgg ctacggtaca actcttggta
    59941 actctcttcg tcgtgtactt ctagcttctc taccaggagc agctgtgaca tctatcaaca
    60001 ttgatggtgt gttacatgag tttgacacag ttccaggtgt tcgtgaagac gtgatgcaaa
    60061 tcattctgaa cattaaagga attgcagtga aatcgtacgt tgaagacgaa aaaatcatcg
    60121 aactggatgt tgaaggtcct gctgaagtaa cagctggtga cattttgaca gatagcgata
    60181 ttgaaattgt aaatccagat cattatctct ttacaatcgg tgaaggttct tctctaaaag
    60241 cgactatgac tgttaacagt ggtcgtggat atgtacctgc tgatgaaaat aaaaaggata
    60301 atgcaccagt tggaacactt gctgtagatt ctatttatac accagttaca aaagtcaact
    60361 atcaagtgga acctgctcgt gtaggtagca atgatggttt cgacaaatta acccttgaaa
    60421 tcttgacaaa tggaacaatt attccagaag atgctttagg gctttcagca cgtattttga
    60481 cagaacatct tgatttgttt acaaatctta ctgagattgc taagtcaact gaagtgatga
    60541 aagaagctga tactgaatct gacgaccgta ttttagatcg tacgattgag gaactggact
    60601 tgtctgtgcg ttcatacaac tgtttaaaac gtgccggtat caatactgtg catgatttga
    60661 cagaaaaatc tgaagcagag atgatgaaag tacgaaatct tggacgcaag agtttggaag
    60721 aagtgaaact caaactcatt gatttgggtc ttggattaaa agataaataa aggaggaata
    60781 catggcttac cgtaaactag gacgcactag ctcacaacgt aaagcaatgc ttcgcgattt
    60841 gacaactgac cttttgatca acgaatcaat cgtgacaact gaagctcgtg ctaaagaaat
    60901 ccgtaaaact gttgaaaaaa tgattactct aggtaaacgt ggtgatttgc atgcacgtcg
    60961 tcaagcagct gctttcgtac gtaatgaaat cgcatctgaa aactatgatg aagcaactga
    61021 taagtacact tctactacag cacttcaaaa attgttctca gaaatcgcac ctcgttatgc
    61081 tgaacgtaac ggtggataca ctcgtatcct taaaactgaa ccacgtcgtg gtgatgcagc
    61141 gccaatggcg atcatcgaat tagtataaaa tcatcaattt tgttgagtgt tatgatgatg
    61201 gagtcttgtg ctcttagtct agctctggtc taccgctagg atttcggtcc tagcgggaac
    61261 actcatcata agttgggata gtagacgctt gtttacgaaa ttgttttttt cttaagaaca
    61321 acttcgtaag caggcgtttt tgagtatttt cgttagaatt atgctatact atttgaaaag
    61381 aatcctgttt aatgttaagg tttcttattt taagaagaat tggagtttac ttatgaaagc
    61441 cattataact gttgttggta aagataaatc tggaattgtt gcaggtgttt ctggtaaaat
    61501 tgcagaatta ggattgaata ttgacgatat ctctcaaact gtcttggatg aatattttac
    61561 gatgatggct gttgtatcta gtgatgaaaa gcaagatttt acctatcttc gtaatgaatt
    61621 tgaagctttt gggcaaactt tgaatgtaaa aatcaatatt cagagtgcag cgattttcga
    61681 agctatgtat aatatctagg aggttatcat ggatattaga caagttactg aaaccatcgc
    61741 catgattgag gagcaaaatt tcgatatcag aaccattacc atggggattt ctcttttgga
    61801 ttgtatcgat ccagatatca atcgtgctgc ggagaaaatc tatcaaaaaa ttacgacaaa
    61861 ggcggctaat ttagtagctg ttggtgatga aattgcggct gagttgggaa ttcctatcgt
    61921 taataagcgt gtatcggtga cacctatttc tctgattggg gcagcgacag atgcgacgga
    61981 ctacgtggtt ctggcaaaag cgcttgataa ggctgcgaaa gagattggtg tggactttat
    62041 tggtggtttt tctgccttag tacaaaaagg ttatcaaaag ggagatgaga ttctcatcaa
    62101 ttccattcct cgcgctttga ctgagacgga taaggtctgc tcgtcagtca atatcggctc
    62161 aaccaagtct ggtattaata tgacggctgt ggcagatatg ggacgaatta tcaaggaaac
    62221 ggcaaatctt tcagatatgg gagcggccaa gttggttgta ttcgctaatg ctgttgagga
    62281 caatccattt atggcgggtg cctttcatgg tgttggggaa gcagatgtta tcatcaatgt
    62341 cggagtttct ggtcctggtg tggtgaaacg tgctttggaa aaagttcgtg gacagagctt
    62401 tgatgtagta gccgaaacag ttaagaaaac tgcctttaaa atcactcgta tcggtcaatt
    62461 ggttggtcaa atggccagtg agagactggg tgtggagttt ggtattgtgg acttgagttt
    62521 ggcaccaacc cctgcggttg gagactctgt ggcacgtgtc cttgaggaaa tggggctaga
    62581 aacagttggc acgcatggaa cgacagctgc cttggccctc ttgaacgacc aagttaaaaa
    62641 gggtggagtg atggcctgta atcaggtcgg tggtctatct ggtgccttta tccctgtttc
    62701 tgaggatgaa ggaatgattg ctgcagtgca aaatggctct cttaatttag aaaaactaga
    62761 agctatgacg gctatctgtt ctgttggatt ggatatgatt gccatcccag aagatacgcc
    62821 tgctgaaact attgcggcta tgattgcgga tgaagcagca atcggtgtta tcaacatgaa
    62881 aacaacagct gttcgtatca ttcccaaagg aagagaaggc gatatgattg agtttggtgg
    62941 tctattagga actgcacccg ttatgaaggt taatggggct tcgtctgtcg acttcatctc
    63001 tcgcggtgga caaatcccag caccaattca tagttttaaa aattaagaaa ataggagaaa
    63061 ttttaagttc tatttaagat tagatgtgta tactataatc attaaataaa gacctcctaa
    63121 tattatttga aacagataac actgaattag tttgaatttg attttcatct aatatcttta
    63181 tttaatgaac tcctaaactt tttcataata atctccttca aaagtcgcct gtatgggtgg
    63241 cttttatttt atcattcatg atataataga agcaaacgga ggacggaaaa tggtaaaagt
    63301 acgattgtat ttgatacgtc atggcaagac catgtttaac acgattggtc gcgcgcaagg
    63361 ttggagcgat actcccttaa ctgctgaagg tgaacgaggg attcaagagt taggaattgg
    63421 tttgcgagaa tctgatctac agtttgagcg cgcttattcg agtgattctg gtcgtaccat
    63481 tcagaccatg ggaattatcc ttgaagaact tggcttgcag gggaaaatcc cttatcgcat
    63541 ggacaagcgt atcagagaat ggtgtttcgg tagttttgat ggagcctatg atggcgatct
    63601 tttcatgggc attattcctc gtatctttaa tgtggaccac gttcaccaat tgtcttatgc
    63661 tgaactggct gagggcttgg tagaggtcga tacagctggt tgggctgaag gctgggaaaa
    63721 actcagtggc cgaatcaagg aaggctttga aatgattgca aaagaaatgg aagatcaagg
    63781 tggaggtaac gcccttgttg tcagccatgg aatgactatt ggaaccattg tttatctgat
    63841 taatggcatg catccgcatg gtctagataa tggtagcgtg acgattcttg aatatgagga
    63901 cggtcagttt agggttgaag ttgtcggtga ccgtagttac cgagagctag gacgtgagaa
    63961 gatggaagaa ggctctattt aatcagtcta gacttgcttg ccatgagcta gggatttgat
    64021 aagaatatca agataagaaa aaacagccga gggtactcct ttcggctgtt tttgatgtgg
    64081 aaaactaaag tgtaatgcta ttgcttttag agattttcat aaacaagagc aaggaaccta
    64141 ctgttagaac agtcaggata gttgacaagg ctgcggctac accgtaattt cctctgagaa
    64201 cctctgtata aatagctaca gtcattgttc ttgttttgac attgtagagg aggatagaag
    64261 tagagagttc tgaaatcagt gtgacccaag ataggatggc tccagaaata atatccgata
    64321 gcatcattgg agttgtaatc ttagcaaaga tattgagacg actacttcct aagctttcag
    64381 cagcttcttc aatacttggt gctatttgtt gtaagctagc aacagatgag cgaatagtat
    64441 aaggtaattt tctggcagat agagacataa tcaagatgaa agcagtccct gtaatcataa
    64501 gaaatccact tccaaataga ccagagaaat gaaggcaatc cctagaacgg ttcctggtac
    64561 aatataaggt accatactga ggctgtcaat taagtttgta aacaaattcc gttttctaac
    64621 ggctaggtag gagataaatg tcgcaaatag aacaactaga actaaggcaa tcaaagggat
    64681 acgaatggta ttgaaaatag cagatcccat acgatggaaa gctaccttgt aactgtttgg
    64741 agaataacct ttaacagata ccatacctga tgtttttagg aaagaggtat aaattaagta
    64801 gatttgaggt aaaacagaga taaagataat tccgtagact gttgcataaa tggcagctat
    64861 ttttcctttt gtagtttttt taggctcaat tggatggagc agattcatgc tgaaactgta
    64921 gcggtttgca atgtgttttt ggataaggaa aattgccaag gcaatgataa tcgccataat
    64981 tgcaaaagca gaatttcctc caacctcgct aataaattgg gtataaatca ggacagggaa
    65041 agtccgatat ccttcgccaa tcaacatagg cgttccaaag tctgagaatg ctctcataaa
    65101 tacaagcaag gagctgctag taaggttgga actaggagag gtaaaacaac cgttacgata
    65161 cgcttaaatc cgaaggaccc ccatgctttc agctgcttca agtagagaat tgtcaatact
    65221 gttcattgtt ccagcaacat atagaaatac cagtgggaat agttgcagtg taaagacaag
    65281 tacaattcct ttgaatccat aaatatcgat agctggaaga tgaagggcat ttgtcaaaaa
    65341 tttagtgatg accccatttc gtcctagcaa gagaacccag gagtaggctc ctacgaaagg
    65401 agctgacatg gaagcaatga taatcaatat ttgtagaaat ttctccccct tgaagtcata
    65461 catagagaag agataagcta atagggttcc tacaactaag gaagtgacag tagcggtaat
    65521 ggaaaccttg aaactgttga ctagtgtctc agagtagtag actttactaa agaaagtgac
    65581 aaaattagct agtgagaatt atccttcatg tataagtgct tacttgagca cggtaatgat
    65641 aggataaacg agaaagacaa gataggtaag aaagatgaag aaagaggagg ctgtccaaat
    65701 atttagtttt ttacattcca tggttgactc cttttatcag gttttgggaa ccatctgcag
    65761 aaaagatgtt taatttttgc gtattgattc gtagacgaat acgattgtct ttttgtagat
    65821 cttcttcaaa agttgattct tcactaactt gaatttttga ggcaaaacct gtctcaatga
    65881 aatactccgt atttagtcca agatagacgc tatcgctaat agttccttca atatctccag
    65941 attcatcttt gataaactct tcgggacgaa tgcttacatg aatagcttgc tcctcaacct
    66001 gatcaagagc tggcattcga agggcatagc catctgaaaa gacgatataa gcgccgtcgc
    66061 tccgtttttc aagattggca gggataatat ttgtgcgtcc gataaaggtt gccacaaact
    66121 cattagctgg tttatgatag agttcttttg gtcggccgat ttgttggatc accccatctt
    66181 tcataacagc aatttgatct gaaatagcca tggcttcttc ttggtcgtgg gttacataaa
    66241 cagttgtaat tcccacttcg tgttggattt ctcggatggc ttgacgcata tccaagcgaa
    66301 gtttggcctc cagattacta agtggctcgt ccatgaggag aacacttgga ttaaccgcta
    66361 aggcgcatgc caaggtgaca cgttgttgtt gtccaccact gagtttatcg ggctttcgat
    66421 ccgcatattg agcaatttgc atgagttcaa gatacttgtt ggtctgttga atcaattctt
    66481 cttttggaac cttcttttgc ttaagaccaa aagcaacgtt gtctcggaca gtcaaatgtg
    66541 ggaaaatagc gtagttttgg aaaaccatcc cgatattgcg tttgctgggt tccatattat
    66601 tgatttttgt atcatcgaag taaaattctc catctttgat actgttgaaa cctgcaatca
    66661 tacgaagaag ggtcgttttc ccacatcctg aaggtccaag aagggtaaag agacttcctt
    66721 ttggaattgt aatgttcaaa ttctcaataa cagggacatc gtggtagatt ttttggcgtt
    66781 aataattttg atctcactca tagtgaacct tttttactgt ttagattgga tatctgtaaa
    66841 gacttcgttg tatttcttaa cgatatctga tttattcttg atgacataat cataatcttc
    66901 agtgagtgtt ttgattttgt caattggttt catgttttcg cttgttttag catttttacg
    66961 aacaggacgg ttagtagtgg ttgtaccaag tgtatcttgt acttcttgag agataataaa
    67021 atcgataaat ttcttgtcat tttccatatt tttagctttt ttaacgatag cagcactagc
    67081 aggtaggaag acggttcctt cttttggata gactacttta atgttagctc cgtcatttaa
    67141 gagtttaact gctggatcct cataagagag accaacagcc atttctccat caacgactgc
    67201 tttatagaca ccagatgaac ttgaaccgat tttatagtgt attgaaacta gaatagtaca
    67261 cctctacttc taaaacattg ttagaaatcg atttgactgt cctgattaat ttgtcctgtt
    67321 cttatttcat ttcactatgc catcaataag tgtgaaaaga tcttttacat aagaccaagc
    67381 cttatcatct ttgtaaccac cttgagcttg tagcatattt gttaattgag caaaggcgct
    67441 agaagagttt gctgggtcag cagttgcgat ttttcctttt agttcaggtt tgagaaggtc
    67501 gctatatcct tcgatgttca tgcctttagt taaatcaggg ttgacgatta aaacactacc
    67561 atctagtgta taaggagtag agaagccagt tgtgttttga tattctttga taacattatc
    67621 attttctttt gaaatatagt tttcaaagag ttctccgtgg gtagcatatt gtgtataaga
    67681 accaccaaag ataacatcag ctacaggaac ttctttttct gactctagtt ttttgaaaag
    67741 ttctccagta ccagcttgaa tcagttctat tttgatacca tatttttctt caaaggcagg
    67801 aatagttgct ccaattaagc cttctgagtt tggtgaataa acgactagcg aaccaccgtc
    67861 tcctttatca gatgaactgt catcggcaga ttcattagaa gaacaagcag cataatacat
    67921 ctatttcttt ttcatgatgg atatctccgt tgtgttattt aagtttattt taaaacaatg
    67981 taagcgtttt taaaacctac aattctattc tatagtgtat tgaatctata acagtacact
    68041 ttgactgcta aaatatttct ataaattaat ttgactttcc tgatagagat gttcacatct
    68101 tatttcaatt cactatatta gagtaaaatt ctctacaaaa agaagaatag cctatttgac
    68161 tattcttccg agtgatttca atttctttgg ggaaatatgg agatactttt taaatacttt
    68221 ggcaaaatat ttatagtctg aaaatccaac ttggtcagag atagcgctta aaggggagtt
    68281 gggagattca gccatcttat ctatagcttg tttcaggcga tattgtaaga tatattcatt
    68341 tagagtcatg gggaagtctt ctttgataac cttatataga tgcttgttat ctgcaaatag
    68401 ctagagcatt tcaaggaaat aaactagaaa taacaattaa tatggtggtt cagaaatacc
    68461 ttttgataat caataagatc ttcaggatga agtgcgttga ttccatccat ttcatatttc
    68521 cgatttaata aacgatattt gttttcacca aattgatgaa aagggagtag ttgaacttgg
    68581 tcgatattta atgagttaaa tagagtagcg aatttttctg catcctctaa actattgtta
    68641 aaattaggaa taactgggat tcttaaaacg atagttttat tttgagaaaa agcataatga
    68701 a
//
LOCUS       DAVKBK010000005        67458 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVKBK010000005 DAVKBK010000000
VERSION     DAVKBK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67458
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.005"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(21..956)
                     /locus_tag="VWX69_000317"
     CDS             complement(21..956)
                     /locus_tag="VWX69_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU9191724.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(953..1813)
                     /locus_tag="VWX69_000318"
     CDS             complement(953..1813)
                     /locus_tag="VWX69_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9191725.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRAGQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1921..4083
                     /locus_tag="VWX69_000319"
     CDS             1921..4083
                     /locus_tag="VWX69_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU9191726.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4175..5434
                     /locus_tag="VWX69_000320"
     CDS             4175..5434
                     /locus_tag="VWX69_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9191727.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5448..6314
                     /locus_tag="VWX69_000321"
     CDS             5448..6314
                     /locus_tag="VWX69_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9191728.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            6328..7161
                     /locus_tag="VWX69_000322"
     CDS             6328..7161
                     /locus_tag="VWX69_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9191729.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7162..7242
                     /locus_tag="VWX69_000323"
                     /pseudo
     CDS             7162..7242
                     /locus_tag="VWX69_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7519..8961
                     /gene="gtfA"
                     /locus_tag="VWX69_000324"
     CDS             7519..8961
                     /gene="gtfA"
                     /locus_tag="VWX69_000324"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU9191730.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9099..10292
                     /locus_tag="VWX69_000325"
     CDS             9099..10292
                     /locus_tag="VWX69_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU9191731.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVFCLYIIS
                     LIFTGDMKSILQKMGEHSMLLLFLGYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            10978..12957
                     /locus_tag="VWX69_000326"
     CDS             10978..12957
                     /locus_tag="VWX69_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9191732.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKTSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13024..14520
                     /locus_tag="VWX69_000327"
     CDS             13024..14520
                     /locus_tag="VWX69_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191733.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14520..15446
                     /locus_tag="VWX69_000328"
     CDS             14520..15446
                     /locus_tag="VWX69_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191734.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15455..16522
                     /locus_tag="VWX69_000329"
     CDS             15455..16522
                     /locus_tag="VWX69_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191735.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16533..17459
                     /locus_tag="VWX69_000330"
     CDS             16533..17459
                     /locus_tag="VWX69_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191736.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18026..18886
                     /locus_tag="VWX69_000331"
     CDS             18026..18886
                     /locus_tag="VWX69_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9191737.1"
                     /translation="MSQFITHQSLYATREGFVDELAKQGYVEGENIEIDLQNAQGEQR
                     NLKTISQQLAESSDVVLAIARPSAQSLANTTQTTPVIFSAVTDPVSAKLVESREHPGG
                     NVTGTSDQSSDAISTQINLIKKVLPKAKTIGILYTQSEPNSVVQKDEAKRLLKEKGFT
                     VVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQVSIKHKVPVFGGSTE
                     MIAVGGLYNYGTNYEELVRQTARMLIRVLKGEKPENIAVELPEKLELHTNQEMADALG
                     IDISKLEGKE"
     gene            18898..19791
                     /locus_tag="VWX69_000332"
     CDS             18898..19791
                     /locus_tag="VWX69_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191738.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLTGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            19804..20607
                     /locus_tag="VWX69_000333"
     CDS             19804..20607
                     /locus_tag="VWX69_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9191739.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20640..21350)
                     /gene="treR"
                     /locus_tag="VWX69_000334"
     CDS             complement(20640..21350)
                     /gene="treR"
                     /locus_tag="VWX69_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU9191740.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIREQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21535..23502
                     /gene="treP"
                     /locus_tag="VWX69_000335"
     CDS             21535..23502
                     /gene="treP"
                     /locus_tag="VWX69_000335"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU9191741.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            23680..25305
                     /gene="treC"
                     /locus_tag="VWX69_000336"
     CDS             23680..25305
                     /gene="treC"
                     /locus_tag="VWX69_000336"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU9191742.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25561..25809
                     /locus_tag="VWX69_000337"
     CDS             25561..25809
                     /locus_tag="VWX69_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU9191743.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26016..26810
                     /gene="racE"
                     /locus_tag="VWX69_000338"
     CDS             26016..26810
                     /gene="racE"
                     /locus_tag="VWX69_000338"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU9191744.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            26807..27778
                     /locus_tag="VWX69_000339"
     CDS             26807..27778
                     /locus_tag="VWX69_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU9191745.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27754..28275
                     /locus_tag="VWX69_000340"
     CDS             27754..28275
                     /locus_tag="VWX69_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU9191746.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28272..28733
                     /locus_tag="VWX69_000341"
     CDS             28272..28733
                     /locus_tag="VWX69_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9191747.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28724..29464
                     /gene="xerD"
                     /locus_tag="VWX69_000342"
     CDS             28724..29464
                     /gene="xerD"
                     /locus_tag="VWX69_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU9191748.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29464..30192
                     /locus_tag="VWX69_000343"
     CDS             29464..30192
                     /locus_tag="VWX69_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU9191749.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30211..30780
                     /locus_tag="VWX69_000344"
     CDS             30211..30780
                     /locus_tag="VWX69_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU9191750.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            30767..31489
                     /locus_tag="VWX69_000345"
     CDS             30767..31489
                     /locus_tag="VWX69_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9191751.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31489..31731
                     /gene="yidD"
                     /locus_tag="VWX69_000346"
     CDS             31489..31731
                     /gene="yidD"
                     /locus_tag="VWX69_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU9191752.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(31956..32921)
                     /locus_tag="VWX69_000347"
     CDS             complement(31956..32921)
                     /locus_tag="VWX69_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9191753.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLAEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33017..33769)
                     /locus_tag="VWX69_000348"
     CDS             complement(33017..33769)
                     /locus_tag="VWX69_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9191754.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINIASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(33766..34722)
                     /locus_tag="VWX69_000349"
     CDS             complement(33766..34722)
                     /locus_tag="VWX69_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU9191755.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34712..35671)
                     /locus_tag="VWX69_000350"
     CDS             complement(34712..35671)
                     /locus_tag="VWX69_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191756.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36094..36795)
                     /gene="galE"
                     /locus_tag="VWX69_000351"
     CDS             complement(36094..36795)
                     /gene="galE"
                     /locus_tag="VWX69_000351"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9191757.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37196..38260
                     /gene="pepA"
                     /locus_tag="VWX69_000352"
     CDS             37196..38260
                     /gene="pepA"
                     /locus_tag="VWX69_000352"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU9191758.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38282..38578
                     /locus_tag="VWX69_000353"
     CDS             38282..38578
                     /locus_tag="VWX69_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9191759.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            39260..39703
                     /locus_tag="VWX69_000354"
     CDS             39260..39703
                     /locus_tag="VWX69_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9191760.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            39707..40471
                     /locus_tag="VWX69_000355"
     CDS             39707..40471
                     /locus_tag="VWX69_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU9191761.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVIPKVEDLTNRGKF"
     gene            40486..41214
                     /locus_tag="VWX69_000356"
     CDS             40486..41214
                     /locus_tag="VWX69_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191762.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIENGEFMVLVGPSGSGKTTMI
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLTTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41207..42727
                     /locus_tag="VWX69_000357"
     CDS             41207..42727
                     /locus_tag="VWX69_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU9191763.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43072..43878
                     /locus_tag="VWX69_000358"
     CDS             43072..43878
                     /locus_tag="VWX69_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU9191764.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44044..44580)
                     /locus_tag="VWX69_000359"
     CDS             complement(44044..44580)
                     /locus_tag="VWX69_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9191765.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            44713..45603
                     /locus_tag="VWX69_000360"
     CDS             44713..45603
                     /locus_tag="VWX69_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU9191766.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            45847..46200
                     /locus_tag="VWX69_000361"
     CDS             45847..46200
                     /locus_tag="VWX69_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU9191767.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46201..47238
                     /locus_tag="VWX69_000362"
     CDS             46201..47238
                     /locus_tag="VWX69_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9191768.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIIIE"
     gene            complement(47285..48292)
                     /gene="galR"
                     /locus_tag="VWX69_000363"
     CDS             complement(47285..48292)
                     /gene="galR"
                     /locus_tag="VWX69_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU9191769.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGINLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48457..49635
                     /locus_tag="VWX69_000364"
     CDS             48457..49635
                     /locus_tag="VWX69_000364"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU9191770.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49654..51135
                     /locus_tag="VWX69_000365"
     CDS             49654..51135
                     /locus_tag="VWX69_000365"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU9191771.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            51205..51609
                     /locus_tag="VWX69_000366"
     CDS             51205..51609
                     /locus_tag="VWX69_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU9191772.1"
                     /translation="MKDFHFDAISAFESYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            51790..52554
                     /locus_tag="VWX69_000367"
     CDS             51790..52554
                     /locus_tag="VWX69_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEU9191773.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            52551..53012
                     /locus_tag="VWX69_000368"
     CDS             52551..53012
                     /locus_tag="VWX69_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU9191774.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(53063..54325)
                     /locus_tag="VWX69_000369"
     CDS             complement(53063..54325)
                     /locus_tag="VWX69_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU9191775.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGNGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(54325..54906)
                     /locus_tag="VWX69_000370"
     CDS             complement(54325..54906)
                     /locus_tag="VWX69_000370"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU9191776.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(55306..55401)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(55784..56023)
                     /locus_tag="VWX69_000371"
     CDS             complement(55784..56023)
                     /locus_tag="VWX69_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9191777.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(56068..56166)
                     /locus_tag="VWX69_000372"
     CDS             complement(56068..56166)
                     /locus_tag="VWX69_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9191778.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            complement(56178..57005)
                     /gene="xth"
                     /locus_tag="VWX69_000373"
     CDS             complement(56178..57005)
                     /gene="xth"
                     /locus_tag="VWX69_000373"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU9191779.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            57139..57595
                     /locus_tag="VWX69_000374"
                     /pseudo
     CDS             57139..57595
                     /locus_tag="VWX69_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            57592..58122
                     /locus_tag="VWX69_000375"
     CDS             57592..58122
                     /locus_tag="VWX69_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU9191780.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            58250..59995
                     /locus_tag="VWX69_000376"
     CDS             58250..59995
                     /locus_tag="VWX69_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191781.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            59985..61736
                     /locus_tag="VWX69_000377"
     CDS             59985..61736
                     /locus_tag="VWX69_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191782.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            61909..62601
                     /locus_tag="VWX69_000378"
     CDS             61909..62601
                     /locus_tag="VWX69_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU9191783.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            62644..63870
                     /locus_tag="VWX69_000379"
     CDS             62644..63870
                     /locus_tag="VWX69_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU9191784.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            65001..67160
                     /gene="pfbA"
                     /locus_tag="VWX69_000380"
     CDS             65001..67160
                     /gene="pfbA"
                     /locus_tag="VWX69_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU9191785.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            67144..67440
                     /locus_tag="VWX69_000381"
     CDS             67144..67440
                     /locus_tag="VWX69_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191786.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
BASE COUNT        19803 a        12424 c        15093 g        20138 t
ORIGIN      
        1 tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc actatttagc
       61 cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga gatgtcttta
      121 gcaagtccct tgtagtcttt ttgctgtagt gtgaaagtga cttcttttcc tagaatgaat
      181 gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa agcacgccag
      241 atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa gctggcagct
      301 ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac tccaataatg
      361 atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat tcctccaatt
      421 ttatgattgt ttagatagat atcattgacc cattttatgt cgacatctat taaagttagg
      481 ttcttaatag ctttgtagac agctccagct acaagtagtg tgtaggatgg taatttgtca
      541 taggggagat ttggtttaag atggagtgtc atataaatac caccttgtgg tgagtagaag
      601 gaacgttgaa aacgtcctcg gcctgctgtt tgataggaag ctagatagag ggtatttgct
      661 tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt ttcgggttta
      721 aagctgactt taattggaag attttcttct agaatctctg gaagaataag gtcaccattc
      781 attagtttat atcctctatt tttgatacta tcaatttcaa tgccttcttg ttctagtcgc
      841 ttgatagctt tccaaattga tgttcggctt agggatagtt tttctgcgat tttttctccg
      901 ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga tttcataatg
      961 ttgcctttct cactagttgg tattgagagt attcttttct tgtatgactt ggagtctgat
     1021 taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct accgagtatg
     1081 caattacctt gatggactct tgggtatttt cgagaagttg tccagctcgg tgcattcgaa
     1141 cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg cttgataagt
     1201 agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat tgaggatagt
     1261 ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa atattctttt
     1321 ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt tgtcccatga
     1381 tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca atgtctgaga
     1441 tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag gattgatcag
     1501 aaatttggga aagagcaaaa taatcagggg ctttccctcc agtgattcct aaccagtagt
     1561 aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt tttaatagaa
     1621 agaaatctcc ttcttttaaa tcaacaattt tacccttgta atgaaatttt ccttgtcctt
     1681 tagtaatgta atgtagaacg tatgtatcac gaatggctgg accaaaagag taattaggtg
     1741 tgcattcctc atatccataa aagcttaggg caaggtcgat tgttccagtc tggtattctg
     1801 aaaaaactaa catgtgctac ctcctaccta acattttacc atattcttga gacatttttc
     1861 tattttggaa agcgatttca ggtgataaaa tataatcaat aaagtgatga ggtgaagtaa
     1921 atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct aagtttgatt
     1981 attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat taagaactat
     2041 aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc aacggctact
     2101 aatcgaacct ttagtttaga tactcaacgt caaatttttg gacaacatgg cttaggagat
     2161 tttaggaaac caaccataca ggttcagcat aatgtaactg aagtaacaga ctttcgattt
     2221 gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc tccacatagc
     2281 atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca acttagtctg
     2341 actttgtatt atactacttt taataatgat gcgactattg ctagctacag taaattagat
     2401 aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc tgattttcca
     2461 gctgcagatt atgaaatagc aactctgcag ggtgcttatg ctcgtgaaaa gactgttaga
     2521 cgtcaacagg tagaacaagg aatcttttcg attagttcaa accgaggtgc ttctggtcat
     2581 gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc tgggaatgtg
     2641 tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa aaatcaattg
     2701 aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa gttagcccct
     2761 gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg attaactggt
     2821 attagtcatg aaagtcagaa ttttgtactg aagcacatta tgctaagtga attttctaaa
     2881 aaagaacgtc caattctaat caataactgg gaagctactt actttgactt tcagagagaa
     2941 aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt tgtattagat
     3001 gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg ggttgttaat
     3061 gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga aagaggtttg
     3121 cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt gtatcgtcaa
     3181 catcctgact gggctattca ggttcctgat tatgagcata cttattctcg gaatcaatta
     3241 gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt agatcaactc
     3301 ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat cactaagcta
     3361 gggaatggat taacttatct agagacacag atgcaatctc atcagtacat gctggggctt
     3421 tacgaactcg tttcttatct gacagagaag cacagccata ttctctttga gtcctgctct
     3481 ggtggtggtg gacgaaatga tcttggtatg atacgctatt tcccacaagt ctgggctagt
     3541 gataatactg atgccattgc acgtttacca attcaatacg gttcatccta tctctatcca
     3601 accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg acgaatgaca
     3661 ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga gcttgatttg
     3721 acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt gtataaagaa
     3781 ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga tactgcatcc
     3841 aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta cgttcgcgtt
     3901 ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga tgaagaggga
     3961 ctatataaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat gtatgcgggc
     4021 ttaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt tagaaaacta
     4081 tgatatgtac tgaccccaaa agttagattt attctgtcta acttttgggg tgcagttcaa
     4141 taagggtgta taaatttata aaggaggctt tctaatggaa tggtataaaa aaatcggact
     4201 tcttgcaact acaggtttag ctttgtttgg gctcggcgct tgctccaact atggtaaatc
     4261 tgcggatggc acagtgacca tcgagtattt caaccagaaa aaagaaatga ccaaaacctt
     4321 ggaagaaatc actcgtgatt ttgagaagga aaaccctaag atcaaggtca aagtcgtcaa
     4381 tgtaccaaat gctggtgaag tattgaagac acgcgttctc gcaggagatg tgcctgatgt
     4441 ggtcaatatt tacccacagt ccatcgaact gcaagaatgg gcaaaagcag gtgtttttga
     4501 agatttgagc aacaaagact acctgaaacg cgtgaaaaat gcctacgctg aaaaatatgc
     4561 tgtaaacgaa aaagtttata acgttccttt tacagctaat gcttatggaa tttactacaa
     4621 caaagataaa ttcgaagaac tgggcttgaa ggttcctgaa acctgggatg aatttgaaca
     4681 gttagtcaaa gatatcgttg ctaaaggaca aacaccattt ggaattgcag gtgcagatgc
     4741 ctggacactc aatggttaca atcaattagc ctttgcgaca gcaacaggtg gaggaaaaga
     4801 agcaaatcaa taccttcgtt attctcaacc aaatgccatt aaattgtcgg atccgattat
     4861 gaaagatgac atcaaggtca tggacatcct tcgcatcaat ggctctaagc aaaagaactg
     4921 ggaaggtgct ggctataccg atgttatcgg agccttcgca cgtggggatg tcctcatgac
     4981 accaaatggg tcttgggcga tcacagcgat taatgaacaa aaaccgaact ttaagattgg
     5041 gaccttcatg attccaggaa aagaaaaagg acaaagctta accgttggtg cgggagactt
     5101 ggcatggtct atctcagcca ccaccaaaca tccaaaagaa gccaatgcct ttgtggaata
     5161 tatgacccgt ccagaagtca tgcaaaaata ctacgatgtg gacggatctc caacagcgat
     5221 tgaaggggtc aaacaagcag gagaagattc accgcttgct ggtatgaccg aatatgcctt
     5281 tacggatcgt cacttggtct ggttgcaaca atactggacc agtgaagcag acttccatac
     5341 cttgaccatg aactatgtct tgaccggtga taaacaaggc atggtcaatg atttgaatgc
     5401 cttctttaac ccgatgaaag cggatgtgga ttaggagtag agagactatg aaaaaagtat
     5461 tacaaaaata ttgggcatgg gcttttgtgg tcatccccct cttgttacaa gcaattttct
     5521 tctatgtgcc gatgtttcaa ggagcctttt acagttttac caactggaca ggattgactt
     5581 acaactacaa atttgtcggc ttaaacaact ttaagctcct cttcatggat ccaaaattca
     5641 tgaatgcgat tggctttacc gcaatcatta cgattgccat ggtggttggt gagattgcac
     5701 tcgggatctt cattgcgcgt gtcttgaact ctaaaatcaa aggccaaacc ttcttccgtg
     5761 cttggttctt cttcccagct gttttatctg gtttgacagt ggctttgatc ttcaagcaag
     5821 tcttcaacta cggtcttcca gcgattggga atgcccttca tattgaattt ctccaaacca
     5881 gtcttttagg gactaagtgg ggagcaatct ttgcggctgt ctttgtcctt ctttggcaag
     5941 gggtggctat gcccatcatc atcttcctag ctggtttgca atctattcca actgagatta
     6001 cagaggcagc aaggattgat ggtgcgacta gcaagcaagt tttctggaac attgaattgc
     6061 cttacttgct accaagtgtc tctatggtct ttatcctagc cctaaaaggt gggctgactg
     6121 cctttgacca agtctttgcc atgaccggtg gtggtccaaa caatgccaca acctcacttg
     6181 ggctcttggt ttataactat gcctttaaaa acaaccaatt cggttatgcc aatgccattg
     6241 ccgtaatctt gttcctctta attgtagtga tttcgatcat ccaattgaga gtatctaaga
     6301 aatttgaaat ttaagaggag aagcatgatg aaacaagatg aaagaaaagc cctgattggc
     6361 aaatacattc tattgattct aggatcggtt ctgattttag tgccgctcct tgctaccctc
     6421 tttagttcct tcaaacccac taaggatatt gtagataatt tctttggctt tccaaccaac
     6481 ttcacatggg acaactttag ccgtctctta gctgatggga ttggaggcta ttattggaac
     6541 tctgtcgtca tcactgtctt gtctttactt gcagtaatga tctttatccc tatggcagcc
     6601 tactccatcg ctcgcaatat gagtaaaaga aaagtcttta ccatcatgta taccctctta
     6661 atcctcggaa tcttcgtacc tttccaagtc atcatgattc cgattacggt tatgatgagt
     6721 aaactcggtt tggctaatac ctttggtttg atcttgctct acttgaccta tgcgattcca
     6781 cagaccctct ttctctatgt tggctatatc aaaatctcga ttccagaaag tctggatgaa
     6841 gcagcagaga tcgatggggc taatcaattt acaacctatt tccgcatcat cttcccaatg
     6901 atgaaaccga tgcatgcgac aaccatgatc atcaatgccc tttggttctg gaatgacttc
     6961 atgttgccac tccttgtctt gaaccgggat tccaaaatgt ggactctgcc tttgttccaa
     7021 tacaactacg caggccaata tttcaacgac tacggaccaa gctttgcctc ttacgtggtc
     7081 ggcattatca gtatcaccat tgtctatctc ttcttccaac gccatatcat ttcaggaatg
     7141 agcaacgggg cagtgaagta atactcaatg aaaatcaaag agcaaactag gaagctagcc
     7201 gcaggttgct caaaacactg ttttgaggtt gtggatgaaa ctgacgaagt cagtaaccat
     7261 acctacggta aggtgaagct gacgtggttt gaagagattt tcgaagagta taagaagagc
     7321 tcatggaatc tatagtcttt gacacagagg aagagttcag cttgttgata attctatgta
     7381 gaaaacaaga aagtagtact ttgtttatca cagtctatat tagtacgagt ttgatgataa
     7441 atagagattt aaaatgaatt tgatttacga agccagatca tatgagactt ggcttcaatt
     7501 agaaaaagga gagtaatgat gccaattcaa aataaaacca tgttgattac ctattctgat
     7561 agccttggaa ataatcttaa agacttatat gataatttgg aagagcattt tggagatgct
     7621 attggaggag ttcacctttt accatttttc ccatcaacag gtgatcgtgg atttgcgcca
     7681 gttgactacg acgaagtgga ctcagctttt ggtgattggg aggatgttaa gcgtttaggt
     7741 gagaaatatt atcttatgtt tgattttatg attaatcata tttctcgtca atccaagtat
     7801 tataaggact atcaagaaaa acatgaagcc agtgaattta aagatctctt tttaaactgg
     7861 gataagtttt ggccagaaaa ccgtccgaca cagtctgatg tagatttaat ttacaagcgt
     7921 aaggatcgtg caccaaagca agagattgtg tttgaagatg gttcagtgga acatttgtgg
     7981 aatacctttg gtgaggagca gattgatctt gatgtgacca aagaagtaac tatggaattt
     8041 atccgtaaga ccattcagca cttggcaagt aatgggtgtg atttgattcg tctagatgcc
     8101 tttgcttatg cagtgaagaa attggatact aatgatttct ttgtggaacc agatatttgg
     8161 gatttattgg acaaagttcg agatatcgct gctgagtatg ggacagagct tttacctgag
     8221 attcatgaac actattcgat tcagtttaaa atagcagacc atgattacta tgtttatgat
     8281 tttgctcttc caatggtgac actttatact ctttacagtt ccagaacaga gcgtttggct
     8341 aagtggttaa agatgagccc gatgaagcaa tttacgacgc tagataccca tgatgggatt
     8401 ggagtagtag atgtcaagga tatcctgacc gatgaggaga ttgactatgc ttcaaatgaa
     8461 ctctataagg ttggagccaa tgtcaaacgt aagtactcta gtgccgagta taacaactta
     8521 gatatctacc aaatcaattc aacctactat tcagcgcttg gagatgatga tgtcaagtat
     8581 tttctcgctc gtctaattca agcttttgcc ccaggtattc ctcaggttta ctatgtgggt
     8641 ctattagcag gcaagaatga cttgaaatta ttagaagaaa ctaaagaagg tcgaaatatt
     8701 aatcgtcatt actatagcaa cgaggaaata gcaaaagaag tgcaacgacc tgttgtgaag
     8761 gcccttctca atctattttc tttccgtaac cgttcagaag cctttgatct agaagggact
     8821 actgagatag agacaccaac agctcacagc attgtaatca aacgtcaaaa taaagataag
     8881 tccgtaacag cagtagcaga aattgacttg caaaatcaga cttatcgggt aattgagaat
     8941 ggagttgaag taacattttg aagccttgat atggtggata aaatagggtt tttattttgg
     9001 aaaacgtttc ctttgttttc aaattgctaa aaaagtggta caatatagga tagcttacta
     9061 ttatctgaat cagctgattt ggagagaaag gattcatttt gaaatcaata ggctttattg
     9121 aaaagctgaa ggggttgtct agtaaagagc tgattttatt gggaattatc ctgagtatct
     9181 ttttaccctt ttatcttttt gtagttgtat tctgtttata tattatcagt ctgattttta
     9241 caggagacat gaaaagtatt cttcagaaaa tgggggagca ttcgatgctg cttctttttc
     9301 ttggctatag tactgttata tccattcttg cacaaaattg gatgggtctt gtggcttcag
     9361 taggaatgtt tctatttact attttctttt tgcactatca gtcgatttta tcccataaat
     9421 tctttcgatt gattttgcag ttcgtcttgt ttggtagtgt cttgtcagct gcttttgcca
     9481 gtttagaaca tttccaaatt gtgaagaaat ttaactatgc ttttctttcc cccaatatgc
     9541 aggtgtggca tcagaaccgg gcagaagtga ccttctttaa tcctaattat tatggaatta
     9601 tttgttgttt ctgtattatg attgctttct atctgtttac aacgaccaag ttgaattggt
     9661 tgaaagtatt ctgtgtgatt gcaggctttg ttaatctctt tggtttgaac tttactcaaa
     9721 atcgaactgc ctttcctgct attatcgctg gagcaattat ctatctcttt acgactatta
     9781 aaaactggaa ggccttttgg cttagtattg gggtcttcgc gattggtttg agtttcctct
     9841 tttctagtga tttgggagtt cgaatgggta ctttagactc ttctatggaa gaacgcattt
     9901 ctatctggga tgctgggatg gccttgttta agcaaaatcc tttttggggt gaagggccat
     9961 tgacctatat gcactcttat cctcggatac atgctcctta tcatgaacat gcccacagtc
    10021 tttatattga tacgattctg agttacggaa ttgtgggtac cattttatta gttctgtctt
    10081 ctgttgctcc tgttcgcttg atgatggata tgagtcagga gtcggggaaa cgtccgatta
    10141 tcggccttta tctatctttc cttacagtgg ttgctgtgca cggaattttt gacttggctc
    10201 tcttctggat tcagtcaggc tttattttct tgctagttat gtgcagtatt ccattggagc
    10261 atcgaatgtt ggtatcggac atgacggatt aagttttata agtttgaaat cttctacctt
    10321 gggtaggaga ttttttatac gatgggcatg tcgtgcatct gaggtgtaag tcctctgtag
    10381 ggatccacta ccggtgaata caatagcgct ccccaagcct gactatcgtg aggtagcgga
    10441 ttaaaatggt ctggggatag atcgttttaa gtctgacgca ggaaataaga attgtcagag
    10501 aaagcaatag tgaaatcgta ggctatgaat agaaacgtga tagcgaggag catatagtgg
    10561 ataaggtagc gagaaatttt aaagtataaa agatagtctt aatctatata tgtaaatcac
    10621 aaaagtaatt gaattcggaa taaggttggt gtgaaaagac atagtaaact gaatcttgaa
    10681 tactagaatg atacttctac aatattgtta taatttaatt tgaattccaa aatcacattg
    10741 ttccgtccgt atttcatttt actgtatgtc ttcctaaact ccaaagtttc tgcgtcaaat
    10801 ttcctatttt cactgtagtc tttgacactt cgaacgacaa tttgaatcat atattcaaaa
    10861 aaaaatgaaa aatttgtgcc aacaagccta aatattctga aaatttgttt gatttttaat
    10921 ggataatgtg atataatggt tgtcaatcta taattcacat aaacagagga gtagaaaatg
    10981 aaaaaaaatc gtgtatttgc tacagcaggt cttgttttat tagcagcagg tgtacttgca
    11041 gcatgcagtt cttcaaaaac atctgattca tcagccccta aagcttatgg ctatgtttat
    11101 acagcagacc cagaaacctt ggactacctg atttcaagta aaaatagtac aacagtagtg
    11161 acttcaaatg ggattgatgg tttattcact aacgataatt acggtaatct tgctcctgca
    11221 gttgcagagg attgggaagt ctctaaggat ggtttgacct acacttataa gattcgtaaa
    11281 ggggttaaat ggtttacctc tgatggagaa gaatatgcag aggtgacggc taaagatttc
    11341 gtgaacggtt taaaacacgc agcagataaa aaatcagaag ctatgtattt agctgaaaat
    11401 tcggttaaag gcttggcaga ttatctatca ggaacttcaa cagatttttc aacagttggt
    11461 gtcaaggcgg ttgatgatta tacgttacaa tacactttga accagcctga accgttctgg
    11521 aactctaagt tgacctattc tattttctgg cctctgaatg aagaattcga aacatcaaaa
    11581 ggaagcgatt ttgctaaacc aacagatccg acatccttgc tttataatgg tccattcttg
    11641 ttgaaagggt tgactgcaaa atcttctgta gagtttgtaa aaaatgagca atattgggat
    11701 aaagaaaatg tccacctaga tactatcaat ctagcttact atgatggatc agatcaggag
    11761 tcgctagagc gtaacttcac tagtggagct tatagttatg cccgtcttta ccctaccagc
    11821 tccaactatt ctaaggttgc agaagaatac aaggacaata tctattacac acaatcaggc
    11881 tctgggattg ctggtctggg tgtgaatatt gatcgccaaa gttacaacta tacttctaaa
    11941 actacagatt cagagaaagt agctactaag aaggcattgc ttaacaaaga tttccgtcaa
    12001 gccttgaatt ttgctcttga tcgctcagct tactcagctc aaatcaatgg taaagatgga
    12061 gcagctttag cagttcgtaa tttatttgta aaaccagact ttgtttcagc tggtgagaag
    12121 acctttggtg atttagtcgc tgctcaactt cctgcttatg gtgatgagtg gaaaggtgtg
    12181 aatttagctg atgggcagga tggtttattc aatgctgaca aggccaaggc agagtttgcg
    12241 aaagctaaga aagctttaga agcagacggc gttcagtttc ctattcatct ggacgttcca
    12301 gtagaccaag catcaaaaaa ctatatatct cgtattcagt cctttaaaca atctgtagaa
    12361 acagttcttg gtgttgaaaa tgtcgttgtt gatattcaac aaatgacaag tgatgaattc
    12421 cttaatatta cttactatgc tgccaatgct tcatctgagg attgggatgt atcgggagga
    12481 gtttcatggg ggccagacta tcaagaccca tctacttacc tggatatttt aaaaacaact
    12541 agcagtgaaa ctacaaaaac atatttagga tttgataatc caaatagccc ttcagtagtt
    12601 caagttggtt tgaaagaata cgataaatta gttgatgaag ctgccaaaga gacaagcgac
    12661 ttgaatgtcc gttatgaaaa atatgcagcg gctcaagcat ggttgacaga tagttcactc
    12721 tttattcctg ctatggcttc ttctggtgca gcaccagtgc tttcacgaat tgttccattt
    12781 actggagctt ctgcgcaaac aggctctaag gggtcagatg tttacttcaa atatttgaaa
    12841 ttacaagata aagcggtgac taaggaagag tatgaaaaag ctcgtgaaaa atggttgaaa
    12901 gaaaaagctg aatcaaatga gaaagctcaa aaagaattgg caagtcatgt gaagtaaata
    12961 atttctaata gaactttctc tccatgagga gaaggttctt ttgggatttt taaaggaaat
    13021 aatatgaaaa aatatatttt tatgcgtgtt ttgcggtcat tggtttcgat tttcttagta
    13081 acgactttga cctacacgat tatctatacc ttggttcctc gaaaattgat tttcaagcag
    13141 gatcctaact ataataaaat tgcgacaacg gctgataaac gtgataacta tgaaaatact
    13201 gtgtttgagc gtatgggcta cattgagtat tacgatacta aagagttgca agaaaaggca
    13261 agtagcatgg attcttctgt aacagtagaa gcaaatgcga ccaataaagc tatttatgaa
    13321 aagtacatca atcaattagg tcatggttgg actttgggag aatttactga aagtggtcaa
    13381 ttctatgcta ctcgtgaaat tccaattttt gaacgtgttt ttcacttcta tgctaacttg
    13441 attgacattg accatacaaa taaaatccaa gaccctgaaa atccagactt gaaacgctac
    13501 cttcgttttg aaaacgatcc agctatcgga tggtcattgg tcggttcagg aactaaacat
    13561 aaatatctct tgtactttaa cagtcagttc ccatttgttc atcaaaactt tgtgaacttg
    13621 aatttaggtg actcttaccc aacctatgct aatacaccag ttcttcaggt tattactcaa
    13681 ggtcaaggac aaaccaaaac tgcccaagtt cagttcccaa caggtaagaa aacgtcttct
    13741 gtaaatattt actcaagaac ctacaagtca cctagtcagg ctgactctcg tgaagtagct
    13801 agctatggga aagatgatcc ttatacagcg actgaaagta attaccaata tccatctatg
    13861 attgtcagct ctgctattac tggtttgatt ggtttggttc ttgcctatgc tcttgccgtg
    13921 ccacttggtt cagccatggc tcgtttcaag aacacttgga ttgatagcct ctcaacaggg
    13981 gctttgacct tcttgcttgc tcttccaacg attgccttgg tttacatcgt tcgattgatt
    14041 ggatcatcta tttcccttcc agattcattc cctatcttgg gagctggaga ttggcgttct
    14101 tacgttttac cagcagtcat ccttggtttg ttgggtgctc ctggtacagc catttggatt
    14161 cgtcgttaca tgattgactt gcaatctcaa gactttgttc gtttcgctcg tgcaaaaggt
    14221 ttgtctgaaa aagaaatttc aaacaaacac atctttaaaa atgccatggt tccgctggtt
    14281 tcaggaattc ctggtgccat tattggggtt atcggtggtg caacccttac tgaaacagtc
    14341 ttcgccttcc caggtatggg taaaatgttg attgactctg taaaagcatc taataactct
    14401 atggtcgttg gtcttgtctt catctttaca tgtatttcta tcttctcacg tcttttggga
    14461 gatatttgga tgactattat tgacccacgt attaaattga ctgagaaagg aggcaaataa
    14521 tgtctacaat cgataaagaa aaatttcagt ttgtaaaacg tgacgatttt gcctctgaaa
    14581 ctattgatgc gccagcatat tcttactgga aatcagtgtt taaacaattt atgaagaaaa
    14641 aatcaactgt agtcatgttg ggaatcttgg tagccatcat tttgataagt ttcatctacc
    14701 caatgttttc taagtttgat ttcaatgatg tcagcaaggt aaacgacttt agtgttcgtt
    14761 atatcaagcc aaatgcggag cattggttcg gtactgacag taacggtaaa tcgctctttg
    14821 acggtgtctg gttcggagct cgtaactcca tcctcatttc tgtgattgcg acagtgatta
    14881 acttggttat cggtgttttt gtcggtggta tttggggtat ttcaaaatca gttgaccgtg
    14941 tcatgatgga agtttacaac gtcatctcaa acatcccacc tcttttgatt gttattgtct
    15001 tgacttactc aatcggagct ggattctgga atctgatttt tgccatgagc gtaacaacat
    15061 ggattggtat tgccttcatg atccgtgtgc aaatcttgcg ctatcgtgac ttggaataca
    15121 acttggcgtc acgtactttg ggaacaccaa ccttgaagat tgttgccaaa aatatcatgc
    15181 ctcaattggt atctgttatt gtgacaacca tgactcaaat gcttccaagc tttatctcat
    15241 acgaagcctt cttgtctttc ttcggtcttg gattaccgat tacagtgcca agtttgggtc
    15301 gtttgatttc ggattattca caaaacgtaa caaccaatgc ttacttgttc tggattccat
    15361 tgacaaccct tgtcttggta tccttgtccc ttttcgtagt tggtcaaaac ttagcggatg
    15421 ctagtgatcc acgtacacat agataggagt agaaatgaca aaagaaaaaa atgtaatttt
    15481 gactgctcgc gatattgtcg tggaatttga cgttcgtgac aaagtattga cagccattcg
    15541 cggcgtttcc cttgaactag tcgaaggaga agtattagcc ttggtaggtg agtcaggatc
    15601 aggtaaatct gttttgacaa agaccttcac aggtatgctc gaagaaaatg gtcgcattgc
    15661 ccaaggtagt attgactacc gtggtcagga cttgacagct ttatcttctc acaaggattg
    15721 ggaacaaatt cgtggtgcta agattgcgac tatcttccag gacccaatga ctagtttgga
    15781 ccccattaaa acaattggta gtcagattac agaagttatt gtaaaacacc aaggaaaaac
    15841 agctaaagaa gcgaaagaat tggccattga ctacatgaat aaggttggca ttccagacgc
    15901 agatagacgt tttaatgaat acccattcca atattctgga ggaatgcgtc aacgtatcgt
    15961 tattgcgatt gcccttgcct gccgacctga tgtcttgatc tgtgatgagc caacaactgc
    16021 cttggatgta actattcaag ctcagattat tgatttgcta aaatctttac aaaacgagta
    16081 tcatttcaca acaatcttta ttacccacga ccttggtgtg gtggcaagta ttgcggataa
    16141 ggtagcggtt atgtatgcag gagaaatcgt tgagtatgga acggttgagg aagtcttcta
    16201 tgaccctcgc catccatata catggagtct cttgtctagc ttgcctcagc ttgctgatga
    16261 taaaggggat ctttactcaa tcccaggaac acctccgtca ctttatactg acctgaaagg
    16321 ggatgctttt gctttgcgtt ctgactacgc aatgcagatt gacttcgaac aaaaagctcc
    16381 tcaattctca gtatcaaaga cacattgggc taaaacttgg cttcttcatg aggatgctcc
    16441 aaaagtagaa aaaccagctg tgattgcaaa tctccatgat aagatccgtg aaaaaatggg
    16501 atttgcccat ctggctgact aggaggaagg aaatgtctga aaaattagta gaaatcaaag
    16561 atttagaaat ttccttcggt gaaggaagta agaagtttgt cgcggttaaa aatgctaact
    16621 tctttatcaa caagggagaa actttctcgc ttgtaggtga gtccggtagt gggaaaacaa
    16681 ctattggtcg tgctatcatc ggtctaaatg atacaagtaa tggagatatc atttttgatg
    16741 gtcaaaagat taatggtaag aaatcgcgtg aacaagctgc ggaattgatt cgtcgaatcc
    16801 agatgatttt ccaagaccct gccgcaagtt tgaatgaacg tgcgactgtt gattatatta
    16861 tttctgaagg tctttacaat caccgtttat ttaaggatga agaagaacgt aaagagaaag
    16921 ttcaaaatat tatccgtgaa gtaggtcttc ttgctgagca cttgactcgt taccctcatg
    16981 aattctcagg cggtcaacgt caacgtatcg gtattgcccg tgccttggtc atgcaaccag
    17041 actttgttat tgcagatgag ccaatttcag ccttggacgt ttctgtacgt gcccaagtct
    17101 tgaacttgct caaaaaattc caaaaagagc tcggcctgac ctatctcttc atcgcccatg
    17161 acttgtcggt tgttcgcttt atttcagatc gtatcgcagt tatttacaag ggtgttattg
    17221 tagaggttgc agaaacagaa gaattgttta acaatccaat tcacccatat actcaagcct
    17281 tgctttcagc ggtaccaatc ccagatccaa tcttggaacg taagaaggtc ttgaaggttt
    17341 acgacccaag tcaacacgac tatgagactg ataagccatc tatggtagaa atccgtccag
    17401 gtcactatgt ttgggcgaac caagccgaat tggcacgtta tcaaaaagga ctaaactagt
    17461 aatggtttta taatttccat gtcaattttt atggaaatta taaaactttt tttgttggac
    17521 tgatttgaaa aactttgaaa gcttcctgaa agaatttttg aaaaatttta aaaattatga
    17581 aatgttattg acaggtgatg aaaaaggtgg taggacagga agcatcaaaa aagaaagcag
    17641 aaaaagaaat gaataagaga caagccgtaa ctatgaatca aaacttttac tttagctact
    17701 ttagatagtg tttgtagaca tgtcaccatg gatgcaaaca gttcaagcaa tttgtttgta
    17761 tctatgtggc taagattttt gattgtggtc catatagatg aatatctaaa tggactagct
    17821 aagttgtaac ttgttaggtt atttcaagta tccgtttaga tagtatctag gcggtttttt
    17881 gttttatctt ttctgagaag gagtttcatt atgaaagttg ttcgaaaatc actagccccc
    17941 tcttggtagt ggggctcctc ttgacttctc tgatcagttt gcatcagttg aaggcagata
    18001 agaaaaagat gtctttcgta tcggtatttc gcaatttatt acccaccagt ccttatacgc
    18061 tactagagaa ggatttgtgg atgagctggc caaacaaggc tatgttgagg gggaaaatat
    18121 tgagattgat ttgcaaaatg cacagggaga acaaagaaat ctaaaaacga tttcccagca
    18181 actagcagaa tccagcgatg tcgttctagc catcgcaagg ccttctgctc agagcttggc
    18241 caatacgacg caaacgacac cagttatctt ttcagctgta acagacccag tcagtgccaa
    18301 gttggttgag tcaagagaac atcctggggg caatgtaact gggacaagcg atcagtcatc
    18361 agatgccatt tcaacccaaa tcaatttgat aaagaaagtg ttgccaaagg ctaaaacgat
    18421 tggaatcctc tatactcaga gcgagcccaa ttcggttgtt caaaaggatg aagctaagcg
    18481 acttctgaaa gaaaaaggct ttaccgttgt tgaaaaaaca atcttggaca gtaataacgt
    18541 caaggcggca gcagagagtt tgatggcaga ggtggatatg gtttttgtcc caactgataa
    18601 tatcatttcg ttaaccatgg aaacagttaa gcaggtttct attaaacaca aggttccagt
    18661 attcggtggt tcaacagaaa tgattgctgt tggtggcttg tataactacg gaaccaatta
    18721 tgaagaattg gtacgtcaga cagctcgcat gctgattcgt gttttaaaag gtgagaaacc
    18781 agaaaatata gcagttgagt tgcctgaaaa actggaattg cataccaatc aagaaatggc
    18841 agatgcattg ggaattgata ttagtaagtt agaaggcaag gaataaggag gattaagatg
    18901 aattttgtgt tatctagttt atcagaaggt ttgttgtggt cgattgtggc gattggggtc
    18961 tacttgactt tccgtatttt ggatattgcg gatatgactg ctgagggagc ctttcctctg
    19021 ggggcagcag tcgttgtatc acagatacag gcaggggcaa atccttggct tgcgacttta
    19081 cttgctttgc tgacaggtat ggtagcaggt cttgtatcag gaatgctcca caccaagatg
    19141 aaaatcccag ctctcttgac agggattgtg accttgacag ggctctattc aatcaatatt
    19201 aaaatcatgg gcagtgtacc caatctttcc ttgggagatt ctgcaaccgt ctttaaacag
    19261 ttggcgagct tgggtctgac aaatgaagga actgttttct cacttagttt ggcctgtttt
    19321 ttacttgttt gtttggtctt gacccttttg atgaaaacag agattggcct ggtcttgcgt
    19381 tcgactgggg ataatatccc gatgagtgag gccaatggag tcaatgtaga caccatgaag
    19441 attgttggtt acatgatttc aaacggtttg attgctctat gtggttcctt gtttgcccaa
    19501 aatgatggat tttcagatgt gacttctggg acaggaacca ttgttgttgg tttgagctcg
    19561 gtgattattg cggaagtctt gatacacgac ttgaccattg gaggccgctt attatccatc
    19621 ggaatcggtg ctattgttta ccgtttgatt attttaaata tctatgaaat tccaaatcta
    19681 gatcaaaact tggtacgtct ctttaatgca atcttgctcg ctttggtttt atttgcacca
    19741 gaattgcaaa agagattaaa gattcgtggt ctgaaattga gaaatgaata ggaggagaaa
    19801 gttatgacaa gtttgttaac acttgaaaat attcacaaga catttgaagc agggacggtc
    19861 aatgagaacc atgtcctcaa aggattagat ttagaggttg aagagggaga ttttatctct
    19921 gtgattggtg gaaatggagc aggaaaatcc actttgatga atatcttggc tggcaatcta
    19981 tcggtggacg aaggggacct tctactggca gggaaatcca ttaaaaatct gagtgtcaga
    20041 aagagagcca aggatattgc ccgtgttttt caagatccta agatgggaac agcttctcgt
    20101 ttgacgattg aggagaatat ggctattgcc ttgagacgcg ggcagaagag agggcttggt
    20161 tggggcgtga aggagaagga tagaatccag ttccaagagg ccttgaagga gttgaatatt
    20221 ggtcttgaaa accgcttaaa agtagatact caatatctct caggaggaca aagacaggct
    20281 ttgactctag tcatgacaga tctgatgaaa ccaaaacttt tacttttgga tgaacatact
    20341 gcggcacttg acccgaaaac cagtcaaatg gtgatggact tgacgcaaaa gattgtggag
    20401 caccatcagt ggacgacttt gatgattacc catgatatga atcatgcgat tgagtacggc
    20461 aatcgtctca ttatgctcta tcaaggcaag atagtggtgg atgtcaaggg agaagagaaa
    20521 aagcatctga cagttgaaga ccttatgcat ctcttccaga aaaatagtgg ccaaagtctg
    20581 gtcagtgatg aattagtttt gggataaaga aaaaggctga gatctggtgt ctcagtcttt
    20641 tatttcttgc gttttgcaaa atctacaaat ctaaatttct ctaacttatg gcgactttcg
    20701 gtaaactgaa attggcgtcc gtcttggaga tagacttttg atttaatcga aacgacataa
    20761 gggtctttgc caatgtccat gagaatcttg tctcggtcgc ttgagtggtc aatggtgatt
    20821 tccttctgag cataatcaat aaggagtttg aggccatttt ctatataaga atagatagac
    20881 tgctcagcaa tttggcgagt gagatttgga attagttcca tatccagata gtccgtatcc
    20941 agaacggata ccagatcatc caccacacgc tggcggacca ccttccaaac catccgaaac
    21001 tctgggaaac cggttatcag tgaggatttt ttatcaataa taatcttgtc cagactgacc
    21061 acgttggttt tagagcgcag tccaagttct ttaactagtt cttggtagct ggttaggttg
    21121 gatacaggga aattgacggt ttcttctttg acgacttgag aaccttgctc tcttatcttt
    21181 ttgatcaatc cttcctcttg gaggagagac agggcctttc ggacggtatc acgactcact
    21241 tgatattgct ccataaggtc gtgctcgcta ggaaggaaat ctccgacagc gtaagtctcg
    21301 ttttgaatgg tttcttggat ttgcttaaat aattgttggt atttcttcat tttgcctgct
    21361 ttaataggtt tttagtctag tttaatgaac acctgtatct attttaccat acaagtgcta
    21421 gaaaatttac aaaaaaacac cctttttata ccaaacaagt tgcagacaag tttggtatcg
    21481 tttacaatat acttatcaaa tcaaacttgc tttgacaagt ataaggagaa tcaaatggga
    21541 aaatttgaac aagaagccaa agatctgctt caggcaattg gaggcaaaga aaatgtgact
    21601 gccgtaactc actgtgcgac acggatgcgc tttgttttag gagatgataa gaaggctaat
    21661 gttaaagcta tcgagtcaat tccagctgtt aaaggaactt ttacaaatgc aggtcaattt
    21721 caggtaatca ttggaaatga cgtgcccatc ttttataatg attttacagc cgtttcaggt
    21781 attgagggtg tttccaaaga agcagccaag tctgcagcta agagtaatca aaacgtggtc
    21841 caacgtgtta tgaccactct ggcggagatt tttactccga ttattccagc cttgatagtc
    21901 ggaggattga tcctcggttt ccgtaatgtc ttggaaggtg tccattggtc gatgttggat
    21961 ggcaagacca tcacagaatc ctctcagttt tgggcaggtg tcaatcactt cctctggttg
    22021 cctggtgaag ctatcttcca gttcttacca gtagggatta cttggtctgt ttctcgtaag
    22081 atgggaacca gccaaatttt gggaattgtt ctcggaatct gtttggtatc gcctcagttg
    22141 ctcaatgcct atgcggttgc ttcaacgcca gcagctgata tcgcggcaaa ctgggtttgg
    22201 aattttggct attttactgt taatcgtatc ggttaccaag cccaagttat cccagccttg
    22261 cttgcaggtt tgagtctgtc ttatcttgaa atcttctggc gcaagcatat cccagaagtc
    22321 atttctatga tttttgtacc tttcttgtca ttgattccag ccttgatttt ggctcatact
    22381 gttttgggac caatcggttg gacaattgga caaggacttt catcagttgt cttggcaggt
    22441 ttaactggtc cagttaaagg gctcttcggt gcaatttttg gtgccctcta cgctccattt
    22501 gtcatcacag gtctgcacca tatgaccaat gccattgata cacaattgat tgcggatgct
    22561 ggtggcactg ccctatggcc aatgattgct ctttctaata ttgctcaagg ctcagccgtg
    22621 tttgcctatt atttcatgca tcgccatgat gagcgtgagg ctcaggtttc acttcctgca
    22681 accatttcag cctatctcgg tgttacagaa ccagctcttt ttggggttaa cgtaaaatat
    22741 atttatccat ttgttgctgg gatgactggt tcagcccttg caggcatgtt atccgttact
    22801 tttaatgtaa ctgcggcttc tattggtatc ggtggtttgc caggtattct ctctattcaa
    22861 cctcaataca tgctgccatt tgcaggaact atgctagttg cgattgttgt tccaatgctc
    22921 ttgactttct tcttccgcaa ggctggtctc tttacaaaaa cagagggcga tacgaacttg
    22981 caggcagaat tcgttgctca agaagaagca gaatttgtga accatgaacc agtagaactt
    23041 acttcggtag aaattatcag cccactaact ggccaagtga aagaattgag tcaagcgacg
    23101 gatcctattt ttgcatcagg tgtcatgggg caaggtctgg tcattgaacc aagccaaggt
    23161 gagttgacct ctccagttaa tgggacagtg acggttcttt tccctaccaa gcatgccatc
    23221 ggcattgtct ctgacgaggg agttgaattg ctcatccaca tcggtatgga tacagtaggt
    23281 cttgatggca aaggttttga aagtcttgta gtccaaggag atcacgttac agttggtcag
    23341 caactgattc gttttgatat ggatgtcatt aaggctgcag gtctggtgac agaaactcct
    23401 gttatcatca ccaaccaaga tgcttataca gcgactattc ccggaactta tccgacaacg
    23461 attcaagctg gagcatctct catggtcgct acacgaatct aatactcttc gaaaatctct
    23521 tcaaaccacg tcagctctat ctgcaacctc aaaacagtgt tttgagcaac ctgtggctag
    23581 cttcctagtt tgctctttga ttttcattga gtataattga aatagcacaa atagggacgg
    23641 aagactgctt cctccctttt atcagaaaag gagaaacaga tgacacttga taaaggaaaa
    23701 gtagtctatc aaatctatcc aaaatcttac aaagacacca ctgaaaacgg tattggggat
    23761 ttccgtggga ttatcgaaaa aattccctat ttagccaaac taggcgtgga tatggtctgg
    23821 ctcaatccat tctatccaag ccctcaacgg gataatggtt acgatatttc agattatatg
    23881 gcagtggatc ctctttttgg tgatatggct gattttgagg aaatggtgtg tgtcggtaaa
    23941 gagcacaaga ttgactttat gctggacatg gtacttaatc attgttcgac agagcatgaa
    24001 tggtttcaga aagccctagc tggtgataag tattatcaag actttttctt catccaagac
    24061 caaccaacag attggcagtc taagtttggt ggttctgcat gggcgccttt cggggatact
    24121 gggaaatact atcttcacct atttgatgag acccaggctg accttaactg gcgcaattcc
    24181 aatgtccgta aggagctttt caaggttgtt aatttctggc gcgacaaggg tgtcaaaggt
    24241 ttccgatttg atgtgatcaa tttgatcggt aaggacgagg tttcagtgga ctgtcctgaa
    24301 aatgaaggga agccagctta tacagacaaa cccatcgttc ataactattt gcgtatgatg
    24361 aaccaagcca cttttggatc tgacgatagc tttatgacag ttggggaaat gtcttctacc
    24421 accatggaaa actgtgtcct ctattcgtcg cctgatcgtc aggaattatc catgaccttt
    24481 aattttcatc acctcaaggt ggactataag gatggacaaa agtggacctt ggctcccttt
    24541 gattttgaag agttgaagag tctttaccat agttggggta aggaaatgag tgataaagac
    24601 ggttggagtg ccctcttttg gaacaatcac gatcaaccac gtgccttgaa ccgttttgtc
    24661 gatattcaaa acttccgcaa ggaaggagcc accatgctag cagccagcat tcacctgtca
    24721 cgtgggacac cttatatcta catgggtgag gaaatcggga tgattgaccc agactatgat
    24781 tctatggctg attatgtgga tgtcgaatcg cttaatgcct atcagatgct cttagaagaa
    24841 ggaaagagtc agcaagaagc cttccagatt attcaagcta agtcgcgtga taattcacgt
    24901 attcccatgc agtgggatac ttctgaaaat gcaggatttt caacaggcac tccatggttg
    24961 aaagtcggta aatcctataa agatatcaat gtagaaaatg aaatcaaagg tctgattttc
    25021 accttctatc aagacttgat tcgactgcgt aaggaaatgc caatcatttc agaaggaaat
    25081 tacaaaccag cctttgaaga tagcaaacaa gtctacgctt ttgaacgcca gtttgaggat
    25141 caaaagttac tagtgctcaa taacttttat gccaaagaag tggaaatcga cttgccagca
    25201 gtctaccaaa atggacagat tttgatttca aactatgaag atgcagaagt gtctgagaaa
    25261 attctactca aaccctatca aacactggct atttatgtaa attaatactc ttcgaaaatc
    25321 tcttcaaacc gtgtcagttt tatctgtaac ctcaaagcgg tgctttgagc aacctgtggc
    25381 tagcttccta gtttgctctt tgattttcat tgagtataaa cttagcaagg agacctcttt
    25441 ttcagaaaag cagggttctt tttgctgtct attccatcct tgaaagtgta gaacaaactg
    25501 gtcagggtgg ctagtttgtg gtataatgaa agggattcaa aaagaaacag gagaaaaatg
    25561 atggatttac ttttagcaat tgtattgatt gtgctagctt ttctaggagg agctcttgga
    25621 ggaatgtact tggttcgtaa gcaaatcgaa aaagaatttg ctgacaaccc acgtttgaat
    25681 gctgaagcag ttcgtactct tttgagtgca aatggtcaaa aaccaagcga agctaaggta
    25741 caacaagttt accaccaaat catccgccaa caaaaggcag cccttgctaa caataaaaag
    25801 aaaaaataaa taaggaaaag tctgggatga aagttccaga cttctcacta tgttggttat
    25861 ggtttaggga tgagactttt tccttgcatt ctattgatat ttgattatga ttaagagaga
    25921 ggtagttgac attctatcaa gctgtcggtc agttcgttca gtacaaggaa tcataatgaa
    25981 cgatcaatca gaaaaaagac tagaaagaag actgtatgga taatcgacca attggttttt
    26041 tggattcggg tgtcgggggc ttgaccgttg tgcgcgagct catgcgccag cttccccatg
    26101 aagaaatcgt ctatattgga gattcggcgc gggcgcccta tggcccccgt cctgctgagc
    26161 aaattcgtga atatacttgg cagctggtca actttctctt gaccaaggat gtcaaaatga
    26221 ttgtcattgc ttgtaacact gcgactgcgg tcgtctggga agaaatcaag gctcaactag
    26281 atattcctgt cttgggtgta attttgccag gagcttcggc agccatcaag tccagtcaag
    26341 gtgggaaaat cggagtgatt ggaacgccca tgacggtaca atcagacata taccgtcaga
    26401 aaatccatga tctggatccc gacttacagg tggagagctt ggcctgtccc aagtttgctc
    26461 ccttggttga gtcaggtgcc ctgtcaacca gtgttaccaa gaaggtggtc tatgaaaccc
    26521 tgcgtccctt ggttggaaag gtggatagcc tgattttggg ctgtactcat tatccactcc
    26581 ttcgccctat tatccaaaat gtgatggggc caaaggttca gctcatcgat agtggggcag
    26641 agtgcgtacg ggatatctca gtcttactca attattttga aatcaatcgt ggtcgcgatg
    26701 ctggaccact ccatcaccgt ttttacacaa cagccagtag ccaaagtttt gcacaaattg
    26761 gtgaagaatg gctggaaaaa gagattcatg tggagcatgt agaattatga caaataaaat
    26821 ttatgaatat aaggatgacc aggactggta tgttgggtct tatagtattt ttggtggcgt
    26881 taacagtttg agcgactata agacagattt tcctctgttt gaattctcca aaatatttgg
    26941 agatgaagag tatggtttcc cgctttcagt tactgtttta cgctatggtt ctacctaccg
    27001 tttgttctcc tttgtggtag acatgcttaa tcaagaaatg ggacgaaact tggaagttat
    27061 tcaacgtcat ggggccctgc tcttggttga aaatgggcaa ctcttgtatg tagaattgcc
    27121 taaagaaggg gtcaatgttc atgatttctt tgagacaagc aaggtcagag aaaccttgtt
    27181 gattgcgact cgtaacgaag gtaaaaccaa ggaattccga gctatctttg ataagttagg
    27241 ctacgatgtg gaaaatctta atgactaccc tgacctgcct gaagtagcag aaacaggtat
    27301 gacctttgaa gaaaatgccc gccttaaggc agaaaccatt tctcaattaa cgggcaagat
    27361 ggttttggca gatgattctg gtctcaaagt cgatgtcctt ggtggcttac caggcgtctg
    27421 gtcagctcgt ttcgcaggtg tgggagcaac tgaccgtgaa aataatgcca aactcttgca
    27481 cgaattggcc atggtctttg aactcaagga ccgctcggct cagttccaca caaccctagt
    27541 cgtagccagc ccaaataagg aaagtttagt tgttgaagca gactggtcag gttatattaa
    27601 ctttgaacct aagggtgaaa atggctttgg ctatgatccc ctcttccttg taggagagac
    27661 aggtgagtca tcagctgaat taaccctaga agaaaaaaat agtcaatctc accgtgcctt
    27721 agccgttaag aaacttttgg aggtatttcc atcatggcaa agcaaaccat cattgtaatg
    27781 agcgattccc atggcgatag cttgattgtg gaagaagtcc gtgatcgcta tgtgggcaaa
    27841 gtcgatgccg tttttcataa cggcgattct gaactacgtc cggattctcc actttgggag
    27901 ggcatccgcg ttgttaaagg gaacatggac ttctacgccg gctacccaga acgtctggtg
    27961 actgagcttg gttcgaccaa gattatccaa actcatggtc acttgtttga catcaatttc
    28021 aactttcaaa agttggacta ctgggctcag gaggaagagg ccgctatctg cctctatggt
    28081 cacttgcatg tgccaagtgc ttggttggaa ggcaagatcc tctttctaaa tccaggttct
    28141 atcagtcaac cacgaggtac catcagagaa tgtctctatg ctcgtgtgga gattgatgat
    28201 agttacttca aagtggactt tttgacacga gatcacgagg tgtatccagg tttgtccaag
    28261 gagtttagcc gatgattgcc aaggagtttg agactttctt gttggggcag gaggaaactt
    28321 ttttgacccc tgctaaaaat ctagctgtgt tgattgatac ccacaatgcg gatcatgcga
    28381 ccctcttgct cagtcagatg acctataccc gtgttcccgt tgtgacagat gaaaaacagt
    28441 ttgttgggac gattggactc agagatatta tggcttatca gatggagcat gacttgagcc
    28501 aagaaatcat ggcggatacg gatatcgttc atatgacaaa aacggacgta gcggttgttt
    28561 cgcctgattt caccattacg gaggtcttgc acaagctagt agatgagtcc ttcttaccgg
    28621 tcgtggatgc agagggtatt ttccaaggga ttattacgcg caagtccatc ctcaaggccg
    28681 ttaatgccct cttgcatgac tttagtaagg aatatgagat tcgatgccaa tgagagacag
    28741 gatttcagcc tttttagagg aaaagcaggg cttgtctgtc aattccaagc agtcctataa
    28801 gtatgatttg gagcaatttt tagacatggt aggtgagcgg atttctgaga ccagtctcaa
    28861 gatttaccaa gcccagctag ccaatctaaa aatcagcgcc cagaagcgaa agatttcggc
    28921 ctgtaaccaa tttctatact ttctctatca aaaaggagag gtggacagct tttaccgctt
    28981 ggaattagcc aaacaagctg aaaagaagac ggaaaagcca gagattctat acctagactc
    29041 tttttggcag gaaagcgacc atccagaggg ccgcttgcta gcgctcttaa tcctagaaat
    29101 ggggctcttg cccagtgaga ttttagccat caaggttgcg gacatcaatc tggattttca
    29161 ggtgctgcga atcagcaagg cttcccaaca gaggattgtc accattccca cggccttgct
    29221 ttcagaattg gaacccttga tggggcagac ctatcttttt gaaagaggag agaaacccta
    29281 ttctcgtcag tgggcctttc gtcagttaga atcttttgtc aaggagaaag gttttccatc
    29341 cttatcagct caagtcttac gtgaacagtt tattctaaga caaatagaaa acaaggtcga
    29401 tttgtacgaa attgcaaaaa aattaggatt aaaaacagtc ctgaccttag aaaaatatag
    29461 ataatggata ttaaattaaa agattttgaa ggacccctgg acttgctctt gcatctggtt
    29521 tctaagtacc agatggatat ctacgatgtg cccattacgg aagtcatcga acagtatcta
    29581 gcctatgtct caaccctgca ggccatgcgt ctggaagtga cgggtgagta catggtcatg
    29641 gctagtcagc tcatgctgat taagagtcgt aaactccttc cgaaggtagc agaagtgaca
    29701 gacttggggg atgacctgga gcaggacctc ctctctcaaa tcgaagaata tcgcaagttc
    29761 aagctcttgg gtgagcactt ggaagccaag caccaagaac gggcccagta ttattccaaa
    29821 gcgccgacag agttgattta cgaagatgcg gagcttgtgc atgacaagac gaccattgac
    29881 ctctttttgg ctttttcaaa tatcctagcc aagaaaaaag aggagtttgc acaaaatcac
    29941 acgacgatct tgcgggatga gtataagatt gaggacatga tgattatcgt gaaagagtcc
    30001 ttgattggac gagatcaatt gcgcttgcag gatttgttca aggaagccca gaatgtccaa
    30061 gaggtcatca ccctcttttt ggcaacccta gagttaatca aaacccagga gctgatcctc
    30121 gtgcaagagg agagttttgg agatatctat ctcatggaaa agaaggaaga aagtcaagtg
    30181 cctcaaagct agacttgata gagaggaaag atgagtactt tagcaaaaat agaagcgctc
    30241 ttgtttgtag cgggtgaaga tgggattcgg gtccgccagt tagctgaact cctctctctg
    30301 ccaccgacag gcatccagca aagtttagga aaattagccc agaagtatga aaaggaccca
    30361 gattccagtt tggctttgat tgagacaagt ggtgcttata gattggtgac caagcctcaa
    30421 tttgcagaga ttttgaagga atactctaag gcgcctatca accagagctt gtctcgggct
    30481 gcccttgaga ccttgtccat tattgcctac aaacagccga ttacgcggat agaaattgat
    30541 gccatccgtg gagttaactc gagtggagcc ttggcaaagt tgcaggcttt tgacctgata
    30601 aaggaagacg ggaaaaagga agtattgggg cgccccaacc tctatgtgac tacggattat
    30661 ttcctagatt acatggggat aaaccattta gaagaattac cagtgattga tgagcttgag
    30721 attcaagccc aagaaagcca attatttggt gaaaggatag aagaagatga gaatcaataa
    30781 gtatattgcc cacgcaggtg tggccagtag gagaaaagca gaagagctga ttaagcaagg
    30841 cttggtgacg gttaacggcc aagtggtgcg tgaactagca accactatca agtcaggcga
    30901 caaggtcgaa gttgaaggtc aacctatcta caacgaagaa aaggtctact atctgcttaa
    30961 caaaccacgc ggtgtgattt ccagtgtgac agatgataag ggtcgcaaga cggttgtcga
    31021 cctcttgccc aatgtcaaag agcgtattta ccctgtgggt cgtttggact gggatacatc
    31081 aggtgtcttg attttgacca atgatgggga ctttacagac gagatgattc accctcgtaa
    31141 tgagattgac aaggtttatg tcgcgcgtgt taaaggtgtg gccaataagg acaatctccg
    31201 ccccttgacc cgtggtcttg agattgatgg taagaaaacc aagccagctg tttatgaaat
    31261 tctcaaagtg gacccagtca aaaatcgctc tgtggtgcag ttgaccatcc atgaagggcg
    31321 taaccatcag gttaaaaaga tgtttgaagc tgttggtctc caagtagata agttgtctcg
    31381 gactcgtttc ggacacctag acttgacagg actccgtcca ggagaatccc gtcgtcttaa
    31441 taaaaaagaa atcagccaac tacacaccat ggctgtaact aagaaataat gaaacgaatt
    31501 ttaatagcgc ctgtgcgctt ttaccaacgt tttatctcac cagtctttcc accctcttgt
    31561 cgctttgagc tgacttgttc caactacatg attcaggcta ttgaaaaaca tggttttaag
    31621 ggggtattga tgggcttggc tcggatttta cgttgtcatc cctggtcgaa aacaggtaag
    31681 gaccccgttc cagaccactt ttcccttaaa cgaaatcaag aaggggaatg aggtggggta
    31741 aatagatttc aaaatgataa aaacgcatcc tatcaggttt gagtaaactt gataggatgc
    31801 gttttagaat gtcaaaattt tatactcttc gaaaatctct tcaaaccgcg tcagctttca
    31861 tctgcaacct caaaacagtg ttttgagcaa cctgcggcta gtttcctagt ttgctctttg
    31921 attttcattg agtattaaat tgagtttgaa gtggcttatt tcaaagcttt ttgtatgtct
    31981 tcaatcatga gttttgttga ttcaagtccg cctccgctta gataccagag gtctggtgtt
    32041 agttggataa tcttaccatt tttagcagca ggtgtttcag cgataagggc attttctagg
    32101 acaccgtcgt tgctagagtt gtccccaccg atggcaaggg tacggttgat gacaaagagg
    32161 atgtcagggt tgatttcttt gacactttca aagctgactt cttgtccgtg gcgtgagtct
    32221 tcaaattttg tatcagttgg tttgaatttc aaggtttggt acaagaaaga gaaacgagat
    32281 ttggcaccaa aggctgccat ttttccttca ttaaggagga tcgcaagggc ttttttgtca
    32341 gagctttcat ttttagtagc gacttcttgg atgctcttgt ctagcttggc caattcttcc
    32401 ttggctttct gtgtaccagt ttcgccgaag gcacttgcta aggattcgat attagccttg
    32461 gtagaagtcc agtagtcgtc cttgcttgct tggaagagaa cggttggggc gatttctttg
    32521 aatttgtcta cgaatttttg tgtacgtggt gaagcgataa tcaaatcagg ctcaagggcg
    32581 gcgatagctt ctaaatcagg ttctttcata gaaccaacat ttttgacagt tcccactagg
    32641 tcttttagat aagtcggaac agtttttgta ggcattccga cgatattttt ttcaaatcct
    32701 aaagcgcgaa tagtatccgc agcgccgagg tcaaaggtca caatcttttc aggaactttg
    32761 gaaagtttga cctcggccag tgaactttta atggttacct ctgttggagc agagctactg
    32821 gtctctgtct gactagtgct tgagtttgta ctacatgcac caagtaggag caagaagctg
    32881 gccactaggg cagtgaaata aagtttaagg gatgttttca taatttctcc tctttaaaat
    32941 gtgataacga tttagggagt ctcttgatct tattgactaa gagactgaag gttctctaac
    33001 ttgagctttt atgttactag ctatagatac agatcttttt gtcattgata tcagctagcg
    33061 tgatgggaat ctcataaagt tgactgagca ggtcagcctg catgatttga tcggttcttc
    33121 ccttgctaaa gacctggccg tccttgaagg cgacaatttc atctgcatac tgactggcta
    33181 tgttgatatc gtggaggacg atgataatgg tcttgccgag ttcctccacc agtcgtcgaa
    33241 gaatctgcat catgctgacg ctttgcttga tatcgagatt gttgagtggt tcgtccagca
    33301 agataaagtc cgtatcctgg gccagtacca tagcgataaa gacgcgctgg agttgccccc
    33361 ctgacaggct attgatgtag cggtctttta agttggtcag ttccaaatag ttcagagttt
    33421 ctcggatttt ttcccagtct tctgatctaa gtcgacctcg gctgtaggga aaacgtccaa
    33481 aactgaccag ttcttcaaca gtcaatttgg cttggtaatt gattttctgt tttaggatgg
    33541 ttagttcttg ggccagttct tgcgaattcc agctctcgat ttcacgtcct ttgatactga
    33601 gaactccctg atctttcttg gttagtctgc tcatgatgga gaggagagtc gattttccag
    33661 caccatttgg accaataaag gctgtcagtt tttgaggact gacttcaagc gaaatgcctt
    33721 gcaaaatatc ctgtttttga atggatttgt caatgttttc cagtttcact gacgagccct
    33781 cctatatagt aagataaaga ataagaagcc acccacactc tcaatgatca tactgatacg
    33841 aatttccagt gcaaagactc gttcaatcaa ggcttgcccc aaggttaagc taataaatcc
    33901 aaccagaatg gccactataa agagtaactt gtgctgatag tctttgacaa tcaggtaggt
    33961 gaggttggcc agcataaagc cgaagaaggc cataggtcct accaaggcag tggccgttga
    34021 ggtcaaaagc acgattcccc agaggagctc tttctgttct ttttcaacat cgagtcccaa
    34081 tatctgagcc gtttctcttt gcaggtgcaa gacatctaga acgactgctt ttcgaaagaa
    34141 aaagattgtc aaagcgagga tgatcagaga accgatggct aggatggaag tgttgagatg
    34201 ttgaaaggag gcaaaaagac tattttgcag tttatcgtat tcgtttggat ccattaggac
    34261 ttgaaggaag gtgctgatat ttcgaaagag acttctgagc gctagacaga tcagcaggat
    34321 gaagaccagg tcttgcttca tcagtgtctt caagtaacct tgtaaggcga gaaagaagag
    34381 ggactggaca agaagtaaga ctaggaattc taagataggg gatttgccaa gttgaagaaa
    34441 cttgctttca aaaaccagta gtagggtttg tagtaggacg tagaaggatt caattcccaa
    34501 aatactaggc gtcaggaagc gattttccgt cagggtttga aaactaatgg tcgaaatccc
    34561 agtcgcgatg gctaccaaga gataaacgat gatcttttgg gaacgcaact tccaagcaaa
    34621 ggctgacaag tgagtgatgg gccaaaagta gagaagacaa gctccgatgg caagaataat
    34681 gagaatccag aagagcttgg tatgtttgct tttagtctgc atcttttcgt ccccctctcc
    34741 agagaagtag gataaagacg agactaccga tgattcctag caagagactg acagacaact
    34801 catagggcct aatcagaact cgggatagga tatcgcaagc cagaactaga ttggcaccaa
    34861 ccagtgcgac catgagtttg gtttgactta gattatctcc atagcgcttg cgaacaagat
    34921 tgggaacgat aactccgaga aatggtaggc cacccacggt aatcatggtg acgcttgtcg
    34981 ttagcgccac cagaaagagg gccagttttt caagtaggga gtaggaaatc cccaaactct
    35041 cgctggtttc tttccctaga ttcatgatgg tgaaggtttg ggataatttc caaacggtta
    35101 tcaggatgat gaggcctaag aagagccact catactgatg ggtctgaatc atggagaagg
    35161 agccctgggt ccaggcagtc atactctgaa ccagattgaa acgataggcg ataacttctg
    35221 tgactgagcc gataatcccg ctatagatga tcccaatcag aggcaacatc cacctttcct
    35281 ttacagtaaa aatggtcata aaggctagga agaagagggt gaatacgatg gatgaaacaa
    35341 aagcgaagag catcttttgg gtcagactag ccgatggaaa gacaaaaagg ctcagcacca
    35401 ttcccagttt ggcggcttca gtcgttccaa ctgtactcgg tgcagcaaac tgattttggg
    35461 taatagtctg catgagaagg cctgccatac tcatactaga ggcagtcagg agaatactga
    35521 tagttcttgg gagacgggac tcttgaaaga ggagccaggt ctgctggtcg aaatcaaata
    35581 gctttcccca tgaaaaatca ctggtcccaa tgctaataga gagaaagact aggagtagaa
    35641 gtaagccaat taaataatga gaaagtttca taccccgtcc tttcatgtag atttggtatc
    35701 gaaagatatc tgcggatata aatgtaacat tatttttcta atctgtcaat aaaatttctg
    35761 acaatttaat aaatacaaca aggagagagc aacaagactt tctcctttgt tatcctattc
    35821 taaaatgttt ttaccttaat ctgataaaat aatatcttcg agggagtagc tagccgtcca
    35881 atcaagatat tgtttagctt ttgaagcatc tgctaggaca ctggctgggt cactagcacg
    35941 tcgagcaaca atctcgtgtg ggatttttta atttagtaat tcttcagcag ttttaaagat
    36001 ttctttgata gtatagcctt ttttagttcc taagttaaag atttgagaag aactgtcttc
    36061 ttgaaatagg tagttcattc ctttaacatg agcctatgca aggtccaaga cataaatgta
    36121 atctcgaata catgaaccgt cacgtgtatc gtagtcatct ccaaatattt ttaagctatc
    36181 attttgtccc aatgcggtct tgttgatatt tggaatgatg tgagttggat ttttcacacg
    36241 cagaccgttt gaagcatcca tttcagcccc agcaacatta aagtaacgga aaataacata
    36301 tttccagtcg tagcgattgg ccatccagta aatcattcgt tcgcccatca gttttgtctc
    36361 tgcataaggg ttgacagggt cgagcagggt atcttcagtc accggcttgt caatacagtt
    36421 atttccatag agagaagcag tcgaagagaa catgattttt tgaatgccaa cttcagataa
    36481 gactttgaga acttggttca taccagcaac gttggcagtg aagtatttac ttggattttc
    36541 aatactttcg ctcacaacaa tttcacctgc acaatggagg acagcatcaa tctgattttc
    36601 ttctaagtaa gcctttaagg cgctagcatc ataaacatcc agttctttaa agctagcacg
    36661 actatccaca gccgctcgat ttcctgtgga gagattatcg aggacatgca ccttatagcc
    36721 agcatttaaa agagctttaa cggtatggga gccaatgtag ctagtcccac ctgtaacaag
    36781 aattgttttg gtcatgattt tttccttttc tagttttgta ctatagtaaa ttgaaataag
    36841 atatgaacaa ctctattagg aaagtcaaat taatttctag aaatgtttca gcagctacag
    36901 cgtactattc caaactcaac caactatata tttaaagaaa gaagaaaggg aagtcaacta
    36961 ttttctgtaa atttcatgaa aaatccaaac aactttgatg gtgtattgtt tttttgtttg
    37021 gaaataaata ttcgagttaa ttttggaatg tttactagat tttgcactac atgcaagaga
    37081 atactatcct tttctaagat agagcaggac taagatacta acttagaaat ccaccttccc
    37141 actatccttc tcctataaaa agtggtaaaa tggatgaaag aaagaaggaa ctgaaatgac
    37201 aacattattt tcaaaaatta aagaagtaac agaacttgct gcagtctcag gtcatgaagc
    37261 gcctgtccgt gcttatcttc gtgaaaagtt gacaccgcat gtggatgaag tggtgacaga
    37321 tggcttgggt ggtatttttg gtatcaaaca ttcagaagct gtggatgcac cgcgcgtctt
    37381 ggtcgcttct catatggacg aagttggttt tatggtcagc gaaatcaagc cagatggtac
    37441 cttccgtgtc gtagaaatcg gtggctggaa ccccatggtg gttagcagcc aacgtttcaa
    37501 actcttgact cgtgatggtc atgaaattcc tgtgatttca ggttctgttc ctccgcattt
    37561 gactcgtgga aaggggggac caaccatgcc agccattgcc gatatcgttt ttgatggtgg
    37621 ttttgcggac aaggctgagg cagaaagttt tggcatccgt cctggtgata ccatcgtacc
    37681 agatagttct gcaattttga cagccaatga aaaaaatatc atctcaaaag cttgggataa
    37741 ccgctacggt gtcctcatgg taagcgagct agctgaagct ttatcaggtc aaaaactcgg
    37801 caatgaactc tatctgggtt ctaacgtcca agaagaagtt ggtctgcgtg gcgctcatac
    37861 ctctacaacc aagtttgacc cagaagtctt cctcgcagtt gattgctcac cagcaggtga
    37921 tgtctacggt ggtcaaggca agattggaga tggaaccttg attcgtttct atgatccagg
    37981 tcacttgctt ctcccaggga tgaaggattt ccttttgaca acggctgaag aagctggtat
    38041 caagtaccaa tactactgtg gtaaaggcgg aacagatgca ggtgcagctc atctgaaaaa
    38101 tggtggtgtc ccatcaacaa ctatcggtgt ctgcgctcgt tatatccatt ctcaccaaac
    38161 cctctatgca atggatgact tcctagaagc gcaagctttc ttacaagcct tggtgaagaa
    38221 attggatcgt tcaacggttg atttgattaa acattattaa accataaggg aggtggtagg
    38281 gatggtagaa ccaaacctag aaagccttat aaaagatctt tacaatcatg ctcgacatga
    38341 tttgagtgaa gatttagttg ctgctctcct agagactact aaaaaactgc ctactacaaa
    38401 tgagcaattg caggcagttc gtctctcaag cctggtcaat cgtgaattgc tcctaaatcc
    38461 caaacatcca gcacctgagt tgctcaactt ggctcgcttt gtcaaaagag aagaagccaa
    38521 gtacagagga actgcgactt ctgcgcttat gtatgaggaa ctttttaaaa tgctttgatt
    38581 ccattgtgga tcaaagcatt ttttataaga cctatctcgt gagcgttcaa atagtagtaa
    38641 caaggaatca tgagaagtca gccgagacca tagtagtgaa gaaacttctg taatggaagt
    38701 ggagtgaagt gaggaatcat caaacggtag gggataggct gtttgaaggg tgctacgaaa
    38761 aagatagggt aaggtgaaat tatagcggaa tgaaataaga tatgaacaaa ttgattaggg
    38821 aaatcaaatg aatttataga aatcttttag cagtcatggc gtcctattct agtttcaaaa
    38881 tgctataaat acgaacaaat tgattgggaa attcaaatcg ctttctatca atgttttaga
    38941 agatacagtg ccctagtcca acttcaatat actataaaag aacagatgga agcaattatg
    39001 atttacttct atctttaaaa taaatgatct gataggaaaa atgtgtcccc tcataaaaaa
    39061 taggatagta cggatggaag gcttttgtag actggaggac gaaggaattt agaaactctc
    39121 gttaaaagtt agttgagccg gagtatggtg gtgtgaataa ttatcaaaaa ttatttccaa
    39181 atcgaaatag ttgacagtta gaacgatgag tgttacaatt attttattca tttcgatatc
    39241 gaaataaatt ggaggtgtta tgaaagatag tcatttgcta gcccatcata ttcgtttgtt
    39301 gaatgggcgg atttttcaaa agttactgag tcaagatcct gaggctcttt ataggggtga
    39361 acagggcaag attttagcgg ttttatggaa tagtgaaact ggctgcgcaa ctgcgacaga
    39421 tatcgcgctt gcgactgggc ttgcgaataa tacgctgacg actatgataa aaaagctaga
    39481 ggaacaaaag cttgtaattg ttagtccgtg tggaaaagac aagcgtaaga agtatttagt
    39541 tttaacggag ttaggcaagt tccagaaaga agtggggcat cgtgtcagtc agaaattgga
    39601 tactatcttt tacaaaggat tttcagagga agaaattcac caatttgaag gttttcaaga
    39661 aagaattttg gcaaatctga aagagaagga aaatgaggtt tagaatatgt cacaacaagt
    39721 gaaaaatgct cacaacctat acatccatgc cattcaagac ggacgagttg ctgaggctca
    39781 agcccagtct gtaggggata cctatatcca acattcgaca ggtgttcctg acgggaaaga
    39841 aggatttgca gccttctttg cagatttctt tgagcgtcat ccagagcgtc agattaagat
    39901 tgtccgcacc attgaggatg gcaatctggt ctttgttcat gttcatcaat atctgaatgg
    39961 tggagaagct caatgggtga cgacggatac tttccgtgcg gatgagaatg gtcgtattgt
    40021 tgagcattgg gatgtcattg actactatcg aacacctgaa aatgaccaac tagatcaaat
    40081 ttttggagat tttgaaatca aggatttgga caagaaagca gaaaataaaa agctggttcg
    40141 ccgtttcttg acagaaactt tccaaaatgg ggagctagag cagtggagtg attatgtggc
    40201 agacgatttg attcagcata atcatgagat tggacaagga agtgctgctt ataaaaacta
    40261 tgtggctgaa tatagtgtca cttttgactt tgttttccaa ctcttaggac aaggaaacta
    40321 tgtggttagc tatggtcaga ctcagattga tggcgttgct tatgcccagt acgatatctt
    40381 ccgtttagag aacgggaaaa ttgtggagca ttgggataat aaggaagtca tacctaaggt
    40441 agaagacttg actaatcgag ggaagtttta aattgaggac aaagaatgat tgaatacaaa
    40501 aatgtagcac tgcgctacac agaaaaagat gtcttgagag atgtcaattt acagattgag
    40561 aatggggagt tcatggtttt agttgggcct tctgggtcag gtaagacgac catgattaag
    40621 atgattaacc gtctcttgga accaactgat ggaaatattt atatggatgg caagcgcatc
    40681 aaagactatg atgagcgtga acttcgtctt actactggat atgttttaca ggctattgct
    40741 ctctttccca atctaacagt tgaggaaaat attgctctca ttcctgaaat gaagggttgg
    40801 actaaggaag aaattgctca aaaaacagaa gagcttttgg caaaagttgg attaccagta
    40861 gctgagtatg ggcatcgact tccaagtgag ctatctggtg gagaacagca acgggtcggt
    40921 attgtccgag ctatgattgg tcagcccaag attttcctca tggatgaacc cttttcggcc
    40981 ttggatgcta tttcgagaaa acagttgcag gttctgacaa aagaattgca taaagagttt
    41041 gggatgacaa cgatttttgt aacccatgat acggatgaag ccttgaagtt ggcggaccgt
    41101 attgctgtct tgcaggatgg agaaattcgc caggtagcga atcccgagac aattttaaaa
    41161 gtgcctgcaa cagactttgt agcagacttg tttggaggta gtgttcatga ctaatttaat
    41221 tgcaactttt caggatcgtt ttagtgattg gttgacagcc ctatctcaac atttgcagtt
    41281 gtcacttttg accttgttac tagctatttt gcttgcgatt cccttggctg tttatcttcg
    41341 ctatcatgag aagttggcgg attgggtctt acagattgca gggattttcc agaccatccc
    41401 gtctctggcc ttgttgggac tctttattcc cttgatggga attgggactt taccggcatt
    41461 gacagctcta gtgatttatg cgatttttcc gattttacaa aatactatta ctgggctgaa
    41521 gggaattgat ccgagtcttc aagaggctgg gattgccttt gggatgacca gatgggagcg
    41581 tctcaagaag tttgaaattc cacttgccat gcctgttatc atgtctggaa ttcggacggc
    41641 agcggtcttg attatcggta cggctacctt ggcgaccttg attggggcag ggggactggg
    41701 ttcctttatc ctgttgggaa ttgaccgtaa taatgccagt ttgattttga ttggggccct
    41761 ttcttctgca gtgctagcta ttgcctttaa cttcctacta aaagtaatgg aaaaagcgaa
    41821 attgcggacg attttctctg gttttgcctt ggtggcttta ttactgggtc tgtcttatag
    41881 tccagccctt ttggctcaaa aagagaagga aaacttgatt attgctggga aaataggccc
    41941 agaaccagaa attttggcta atatgtataa attgctgatt gaagaaaata ccagcatgac
    42001 tgcgactgtt aaaccgaatt ttgggacgac aagtttcctt tatgaagctc tgaaaaaagg
    42061 tgatattgac atttatcctg aatttaccgg tacggtgact gaaagtttgc ttcaaccatc
    42121 acccaaggtg agtcatgagc cagagcaggt ttatcaagtg gcgcgtgatg gcattgccaa
    42181 gcaggatcat ctagcctatc tcaaacctat gtcttatcaa aatacctatg ctgtagctgt
    42241 tccgaaaaag attgctcaag aatatggctt gaagaccatt tcggatttga aaaaagtgga
    42301 agggcagctg aaggcaggct ttacgcttga gtttaacgac cgtgaagatg gaaataaggg
    42361 cttgcaatca atgtatggtc tcaatctcaa tgtggcgact atgcagccag ctcttcgtta
    42421 tcaggcaatt cagtcagggg atattcaaat cacggatgcc tattcgactg atgcggaatt
    42481 ggagcgttat gatttacagg tcttggaaga tgacaagcaa ctcttcccac cttatcaagg
    42541 ggctccactc atgaaagaag ctcttctcaa gaaacaccca gagttggaaa gagttcttaa
    42601 tacattggct ggtaagatta cagaaagcca gatgagccag ctcaactacc aagtcggtgt
    42661 tgaaggcaag tcagcaaagc aagtagccaa ggagtttctc caagaacaag gtttgttgaa
    42721 gaaatgatgg gacagagact ttaaacatac tgaactcaac ttccttaaac gactagataa
    42781 aagaatgctc agacaatttc gtctgggctt ttttgatgtg agaatgactg aatgtcactt
    42841 aaaatggaaa gaaagagaaa attttcatga ttttctaaaa ttttactgta aagacagttg
    42901 actattcata aaataggtgt ataatatttt gtgaactact taacaaataa gaggtttcag
    42961 ctcatgtcga ctaaggttag aaatcttgtg tataggcagt tcattatcta atagagcgtt
    43021 gcgtccgaaa gtctatccag acacggctct ttaaaaacaa aaggagaaat gatgcatact
    43081 tatttgcaaa agaaaattga aaatatcaaa acaaccctag gtgaaatgtc aggtggttac
    43141 cgtcgtatgg ttgcggctat ggctgattta ggattttcag gaactatgaa ggctatctgg
    43201 gatgacctct ttgcccatcg tagttttgcc cagtggattt atttgctggt tttaggaagt
    43261 tttcctctct ggctggagtt ggtttacgaa catcgtattg ttgactggat tgggatgatt
    43321 tgtagcttga cagggattat ctgtgtaatc tttgtatcgg aaggtcgagc aagtaattat
    43381 ctttttggct tgattaactc tgttatttac cttattttgg ccctacagaa aggcttttat
    43441 ggtgaggtgc tgacgacact ttacttcaca gtcatgcagc caattggact tctagtttgg
    43501 atttatcagg cacagtttaa gaaggaaaag caggagtttg tcgcgcgtaa actggacggc
    43561 aagggctgga caaagtatct ttccattagt gtgctttggt ggttggcctt tggcttcatt
    43621 tatcagtcta ttggtgccaa tcgtccctat cgtgattcaa tcacagatgc aaccaatggg
    43681 gtagggcaaa tcctcatgac agctgtttac cgtgaacagt ggatattctg ggcggctacc
    43741 aatgtttttt caatctatct ctggtgggga gaaagcctgc aaattcaagg gaaatatcta
    43801 atttatctca ttaacagtct agttggttgg tatcaatgga gcaaggcagc taagcagaat
    43861 actgatttac ttaactagga aaagatgttt gaaagtgctg ttttgagatt tcgattaaaa
    43921 cagatatagt tgataatcaa ggatttatag tatgaaaaag aggatcggcg ggtcctcttt
    43981 tgttgttgaa aagataaaaa actcagtaac ctagaaataa gacaactgag ctttactcta
    44041 tattcaattt ttaggaatga gaaggtctag ataaaattgg acaacttcct ggcctgtgaa
    44101 atcttgacct tttttgagcc accaggtcaa tgtctcgata aagttggaca cgaccaagtg
    44161 ttggaggtaa gaagtaggca tattagggtg ggcttctttt aaattatcag ctagcacgga
    44221 atagacatgg tgttctagct ctttatggag ttgacggagg aagtagtcat ttttggaaaa
    44281 tagcagactg gtgatatggt cttggttttt atgaaaatgg agaaagaggt gggcgaggta
    44341 gtcctcggtt gaaatggctt gctctctttc aaaaagatga tggaagaggt agcggcagag
    44401 ctggtccaga agaagctcct tactttcata gtgacagtaa aaggtggatc ttcccacatc
    44461 tgcgagatca atgatatcct gaacagtagt ggcctcgtag cccttagcat tcaaaagttg
    44521 tataaaagct tgatagatgg cttttttggt tttgctgata cggcggtcaa tgttagtcat
    44581 atggacactt aaggcaaatt gttcagaact gaataaagct gacgttttgc ttctatcctt
    44641 tctttgagtt ttagtggata atgataatga acaaggtgtt cataaatcta ttataacaaa
    44701 ggaatgagaa atatgaaggc aaaatatgct gtttgggtgg cttttttctt aaatttgact
    44761 tatgccattg ttgagtttat tgcaggtgga gtatttggtt ctagcgctgt tcttgctgac
    44821 tctgtgcatg acttgggaga tgcgattgca attggaatat cagcttttct agaaacaatc
    44881 tccaatcgtg aagaagacaa tcagtacacc ttgggctata agcggtttag cctgctagga
    44941 gccttggtaa cagctgtgat tctcgtaacg ggctctgttc tagtcatttt ggaaaatgtc
    45001 acgaagattt tgcatccgca accagtcaat gatgagggga ttctctggtt aggaattatt
    45061 gcgattacta tcaatctgtt agcgagtctg gtggttggta agggaaagac aaagaatgag
    45121 tctattctga gtttgcattt tctggaagat acgctagggt gggtagctgt tatcctgatg
    45181 gcgattgttc ttcgatttac ggactggtat atcctagatc ctcttttgtc ccttgtcatt
    45241 tctttcttta ttctttcaaa agcccttcca cgtttttggt ctacactcaa gattttcttg
    45301 gatgctgtgc cagaaggtct tgatatcaag caagtaaaga gtggcctgga gcgattggac
    45361 aatgtggcca gccttaatca gcttaatctc tggactatgg atgctttgga aaaaaatgcc
    45421 attgtccatg tttgtctaaa agaaatggaa catatggaaa cttgtaaaga gtctattcga
    45481 attttcctaa aagattgtgg ttttcaaaat attaccattg aaattgatgc tgacctagaa
    45541 actcaccaaa cccataagcg aaaggtgtgt gacttggaac ggagttatga gcatcaacat
    45601 tagaaaaaag tgaaaaatac ttgggtacta tcttatttgg aatagagtaa tttctttatt
    45661 atttaaatat ttcaaaaatt ggtaagagaa gagcattgta taaactccgg atatatgatt
    45721 gttaatgata aaaatttttc gattagatac aaaatgcttg acttggagtc aactcaaagt
    45781 tatataataa gataagtgag ttagaatagc gtgaattcag tgaatgaaat gagaggaggt
    45841 tagcgtgtga atattaaatc tgccagtgat ttgttgggaa tttcagcgga tacgattcgg
    45901 tattatgaac gggttggtct tgtgccaccg attactcgta ctgctactgg gattcgtgat
    45961 tttcaagatc aggatatcga agcgctggaa tttattaagt gttttcgttc ggcgggtgtc
    46021 tctgtagata gtttagttga ctatatgtcg ctctaccaaa agggagatga aacgagagag
    46081 gagaggcttg gtattttaga agaggaaaag caaaaattag aggagcgctt gtctcagcta
    46141 cagacagctt taaatcgttt aaatctcaaa attaaacttt ataaggaagg aaaattttaa
    46201 atgaaatcag cagtatatac aaaggcaggt caggttggac ttgctagcat tgaacgtccg
    46261 caaataatag aagcggatga tgtgattatt cgtgtggttc gtgcgtgcgt ttgtggttca
    46321 gatttatgga ggtaccgtaa tccagaaacg aaagctggac ataaaaatag tggacacgaa
    46381 gcgattggga ttgttgaaga agctggggaa gccattacga cggtgaaacc aggtgatttt
    46441 gtgattgtcc cttttacaca tggatgtggt gagtgtgatg cctgtcttgc tggatttgac
    46501 ggttcttgcg acaatcatat tggcaataat ttggggggtg attttcaggc agaatatatt
    46561 cgcttccact atgcaaactg ggcgctggtt aaaatccctg gtcaaccttc tgattataca
    46621 gaagggatgc tcaagtccct tttgactctt gcagatgtca tgccgacagg ctatcatgca
    46681 gcgcgtgttg caaatgttca aaaaggggac aaggttgttg ttatcggtga tggggctgtt
    46741 ggtcaatgtg ctgtcatcgc ggctaagatg cgtggagcat cacaaattat ccttatgagc
    46801 cgtcatgaag accgtcaaaa gatggctatg gagtcaggtg cgacagctgt tgttgcagaa
    46861 cgtggtcaag aaggaattac caaggtgcgt gaaatcctcg gtggaggagc agatgcagca
    46921 cttgaatgtg ttggtacgga ggctgctata gaacaggcgc taggtgttct tcataatgga
    46981 gggcgtatgg gctttgtagg agtcccacac tataataatc gtgctcttgg ttcgacattt
    47041 atgcaaaata tctctgtagc aggtggggca gcttctgcta caacatacga taagcaattt
    47101 ttactaaaag ccgtccttga tggtgatatc aatccaggtc gcgtctttac ttcaagttat
    47161 aaactggaag atatcgacca agcctacaaa gatatggatg aacgtaagac cattaagtct
    47221 atgattataa tcgaataaaa aacgaatagg agttctaaaa ctcctattcg ttttttatgt
    47281 tatcctattc ttgatttagg gtactttctc ttaatgtcag tctggttccc agcatggtca
    47341 ggctagggat tttccgaccg tggaggactt ccttgttaag aatatccata cctgctcggc
    47401 ccatttcttc agtataaact gtaatactag agaggggagg atagacctgt ttggtcagac
    47461 tagtgtcgtt aaaggaaatg aggctgacgc gatctggcag gttgattcca gcttcttgga
    47521 gggcacggag ggcaccgata gctaaactat cgctggctgc gaaaaatgct ggcggaagtt
    47581 ggtctcccaa gctctgaatg gcctccttca tcaagtcata gccagactgg gcagtaaagt
    47641 ttccttgaaa gatcagttca tcatgataga ttccttttgc ttgactgtag tttctgaaat
    47701 tttccagccg cttatcctca atgatttctt cttggtctgt tgtttcttca aggcctgtta
    47761 gaatcccgat acggtccatt ccttgactga ggaaataatc gacaacctgt ttcatagcag
    47821 tgtaaaaatc cgtgataata caggtatgtc ccagggaaag tgtatcgctg tctagaaata
    47881 caagaggctt ttggtattct tcaaaggcag aaatctgagc tcgactaaac tttccgatgc
    47941 agagaatccc aatcacttcc tcgcttaggg taaaagggtg gtcattaaaa tagcgcaaga
    48001 tatcgtagtc caactcttgg gctctttttt ctattcctag gcgaatctgg tagtagtaga
    48061 ggtcgtctag ctccccttgt tcgctgaccc attgaataat ggcaatcttt tgcttgggtt
    48121 tgtgggactc gcctgtcttg aggtgcttgg tgtagcccag ctcttcagca acggttaaaa
    48181 tacggtgtct ggtttcttct gtaacagata ggctctggtc gcggttgagg acacgggata
    48241 cggtcgcgat tgagacagag gctagctgtg caatgtcttt taaggtagcc ataaatcctc
    48301 cttgattagg ttagtatatc atatttttct tctttttact gatattttag taaaatttta
    48361 gtaaaaagga ttgaccttgg gaaattcctt ggatacaata gaaagaaaac gattacacgt
    48421 taagatggct taacggacag tcaaaggaga attcatatgg cacaacatct tactactgaa
    48481 gtccttcgca aagactttct tgctgttttt ggtcaagaag cagaccaaac cttcttttca
    48541 ccaggccgta ttaatttgat tggtgaacac acagactaca acggtgggca cgtttttcct
    48601 gctgctattt ccttgggaac ttacggtgca gctcgtaagc gtgacgacca agtcttgcgt
    48661 ttctactcag ctaactttga ggacaagggc attatcgaag tgcctctcgc tgacctcaag
    48721 tttgaaaaag agcacaactg gaccaattat ccaaaagggg ttcttcattt cttgcaagaa
    48781 gctgggcacg tgattgacaa aggttttgat ttttatgttt atgggaatat cccaaatggt
    48841 gctggcttgt cttcttcagc atccttggag ctcttgacag gagtcgtggc agagcatctc
    48901 tttgatttaa aactagaccg tttggatttg gttaaaatcg gaaaacaaac agaaaacaac
    48961 tttatcggag tcaactctgg tatcatggac cagtttgcta ttggtatggg ggctgaccaa
    49021 cgtgctattt acttagatac caatacttta gaatacgact tggtgccact tgatttgaag
    49081 gacaatgtcg ttgttatcat gaacaccaac aaacgccgtg aattggcgga ctctaaatac
    49141 aatgaacgtc gtgctgagtg tgaaaaagca gtggaagaat tgcaagttgc cttggatatt
    49201 cagaccctgg gtgaattgga cgagtgggcc gttgaccaat atagctattt gattaaagat
    49261 gaaaatcgtt tgaaacgtgc tcgccatgct gtgcttgaaa accaacgtac ccttaaagct
    49321 caagcagccc ttcaagcagg tgatttggaa acatttggtc gtttgatgaa tgcgtcacac
    49381 gtttctctgg agcatgatta tgaagtaact ggtttggaat tggatactct tgttcacaca
    49441 gcttgggcac aagaaggagt tctcggtgct cgtatgacag gggctggttt tggtggctgt
    49501 gccattgcct tggttcaaaa agatactgtt gaggccttta aggaagctgt aggcaaacac
    49561 tacgaggaag tagttggata cgctccaagc ttctatatcg ctgaagttgc aggtggcact
    49621 cgcgtccttg actagtcaaa aggaggctct atagtgatct tagtagataa atttgtaaca
    49681 catgtcattt ctgaaagttc atttgaggaa atggatcgaa tctacctgac caaccgtgtt
    49741 ttggcacgag tgggagaagg tgttttggaa gttgagacca atctggataa attgattgac
    49801 ctcaaggacc agctagttga ggaagccgtt cgattagaga tgattgagga tagtcagact
    49861 gcgcgtgaaa tccttggtac tgaactgatg gacttggtga ctccttatcc gagtcaggtc
    49921 aatcgtgact tctgggaagc ctatgtccac tctcctgagc aagcgataga ggatttttat
    49981 caactcagtc agaaaaatga ttacatcaaa ctcaaggcca ttgctaaaaa tatcgcttat
    50041 cgtgttccat ctgattatgg agaacttgaa attaccatca atctctctaa gcctgaaaag
    50101 gatccgaaag agattgcggt agccaagttg gtgcaagcta gtaattatcc tcagtgtcaa
    50161 ctttgtttag agaatgaggg ttaccatggt cgggtcaacc acccagctcg cagcaaccac
    50221 cggattatcc gttttgaaat ggttggtcag gaatgggggt tccagtattc gccctatgct
    50281 tactttaatg agcattgtat ctttttagat ggccagcatc gtcccatggc cattagtcgt
    50341 cagagttttg aacgtctgtt ggctatcgta gagcagtttc caggatattt tgctggatct
    50401 aatgccgacc tgccgattgt ggggggctct attctaactc atgatcatta tcagggaggc
    50461 cgtcacgtat ttcctatgga attggctccc ttgcaaaaga ccttccgatt tgctggtttt
    50521 gagcaggtca aggctggaat tatcaagtgg ccaatgtctg tcctacgctt gacttcggat
    50581 tccaaagagg atttgattaa cttagctgat aagattttcc aggaatggcg tcagtattca
    50641 gattctagtg tgcagatttt agcagagaca gacgggacac cgcatcacac catcacacca
    50701 atagcgcgta agcgtgatgg acagtttgag ttggacttgg tcttgcgaga caatcagact
    50761 tcagcagagc atcctgatgg catctatcat ccccacaagg atgtccaaca tatcaagaag
    50821 gaaaatatcg gcttgattga ggtcatgggc ttggcaatct tgccaccacg tctgaaagaa
    50881 gaagtagagc aagtcgctag ctatcttgta ggagaagctg ttacagttgc cgattatcat
    50941 caggagtggg cagaccaact caaatcccaa catccagacc taacggataa agaaaaagcc
    51001 cttgcaatcg tcaaggactc tgtgggtgct atctttgtgc gtgtacttga ggatgcagga
    51061 gtctacaagc agacagaaca agggcagaca gcctttatgc gctttgtgga acaggtcgga
    51121 attttactag actaggagct ttctccttgc acagtcctat aaaaagtagt atcatagtgt
    51181 cgtttgaaat atcaggagga aacgatgaaa gactttcatt ttgacgctat atctgccttt
    51241 gaaagttacg aaattgaaaa aatgagagat ggtcacgttg tggtgacgac caaagtagtg
    51301 aactcatcgc tcaactacta tggcaatgcc catggtggct atctattcac gctatgtgac
    51361 caaatcagtg gtttggtggt tatctcgctg ggacttgatg gggtgacact ccaatcctct
    51421 atcaactacc ttaaggcagg aaaactcgac gatgtattga ccattaaagg agaatgtgtc
    51481 catcaaggtc gtacaacctg tgtgatggat gtggatatca ccaatcaaga gggcagaaat
    51541 gtctgtaagg caacctttac catgtttgtc acaggccaaa ggtctgagga aagacgggta
    51601 agtatataaa gaaaggtgag tgggataaat ttatctcact catttttaat ttatgagata
    51661 tgttagaagg aaatataaaa gagagtgatg aaatacaaat gtaataggta catatatgtg
    51721 gtatactagt tatagtagat tttaattgct tatatcgagt gagttctcat attagtgagg
    51781 aatttttaaa tggaattaca ctttaattta gaattagtag aaacctataa aagtaatagc
    51841 caaaaggcac gtatcttaac ggaggattgg gtttatcgtc agtcttattg ccctaattgt
    51901 gggaacaatc ccttaaatca ttttgaaaat aatcggcctg tagcagattt ttactgtaat
    51961 cattgtagtg aggagtttga actaaagagc aaaaaaggaa atttttcatc aacaatcaat
    52021 gatggtgctt atgcaacgat gatgaagcgt gtgcaggcag ataataatcc taatttcttt
    52081 tttttaactt acacaaaaaa ttttgaggta aataactttc ttgtccttcc gaagcaattt
    52141 gttacaccga aatcgattat tcaaagaaaa ccacttgcac caactgctag acgagcaggt
    52201 tggattggtt gtaacattga tttatcacaa gtaccttcta aaggaaggat atttcttgtg
    52261 caagatggac aagttagaga tccagaaaaa gttacaaaag aatttaagca aggtttattt
    52321 ttaaggaaga gctctctgtc atcaagaggt tggacaatag aaattctaaa ttgtatagat
    52381 aagatagagg gttcagaatt tacccttgaa gatatgtatc gttttgaaag tgacctaaaa
    52441 aatatctttg ttaagaacaa tcatatcaaa gaaaagatta ggcaacagct tcaaatatta
    52501 agagacaaag aaataataga atttaaaggt agaggaaagt atcggaaatt atgaaaacga
    52561 aacaacttgt tgcatcagaa gaggtgtatg atttcttaaa agtcatctgg cctgattatg
    52621 aaactgaaag ccgttacgat aacctaagtt taatcgtctg taccttatca gatcccgatt
    52681 gtgtgagatg gttatctgaa aatatgaaat ttggtgacga aaaacaacta gctttgatga
    52741 aggaaaaata tgggtgggaa gtaggagata aattgccaga gtggctacat agctcctatc
    52801 atagattatt gttaataggt gaattattgg aaagcaatct aaaactgaaa aagtatacag
    52861 tagaaattac agaaacttta tcacgtttag taagtataga ggctgaaaat ccagatgaag
    52921 ccgaacgact tgtaagagaa aagtataaga gttgtgaaat tgttcttgat gcagatgatt
    52981 ttcaggacta tgacactagc atatatgaat aggtagatgt ttttattttg tcacacaaaa
    53041 aagaggctcg cacctctttt tcttatttct ttttatgatt taatacggca ttgaggacaa
    53101 tagcgagtag gctggctacg acgattccgt ttgagaagaa catttggaag gctgtcggca
    53161 tgctgacaaa gagattactg ttgttgagac cgacacctgc agcgattgaa acagctgcga
    53221 taaggaagtt gtgttcattg ttagcaaagt caactcgggc gaggatttgc atcccttgaa
    53281 tagatacaaa accaaacatc accagcatgg caccgccgag gacggagctt ggaatgattt
    53341 gggcaagggc accaaactta ggaagcagtc caaggagaac caggaaacca gctgcgtagt
    53401 agattggcag gcgttttttg atgcctgaca atttaaccaa accaacgttt tgtgaaaatc
    53461 cggtgtaagg gaaggtgtta aagattcctc cgagaagtac cgccaaacct tctgcgcggt
    53521 aaccgttgcg aaggcgcgtg ctgtcgattg gatcttttgt gatatcagac aaggctagat
    53581 aaacaccagt tgactcaacc atagacaccg ttgcgatgat acacatcatg acaatagatg
    53641 agatttcaaa ggttggcatc ccaaagtaga gtggagttgg gacatggaca agtggagcta
    53701 ccgcaacagg agagaagtcc accaagccca tagtagcagc aatggcagtt ccaacaacca
    53761 gaccaatcaa aatagagata gacttgataa atcctttggt aaagatgttg atcaagagga
    53821 taatcagaac agtaatagct gcaagcaaga gactttgacc agttggctct ggaacgttat
    53881 ttcccatatt tccaatagcg acagggatca aggttaaacc aatcgtggta ataacagatc
    53941 ctgttacgat agatgggaag agattggcta cttttgagaa gatgcctgaa acaagaacca
    54001 cgtaaatccc agatgcgata agggcaccaa acatagcgcc attaccatgg ctttgcccaa
    54061 tcataatcaa gggagcgacc gactggaatg caactccaag aacgactggg agtccaatcc
    54121 caaagtattt gttgagttgg agttggagga aggttgccac cccacacatg aagatatctg
    54181 tagaaatcag gtaggtcaac tgctcagctg aatagccaag ggctgtcgca atcatgatgg
    54241 gaaccaggat agatcctgag tacatggcta gtaagtgctg caagcccaga acggctgctt
    54301 gcgagtgttt ttcttgagtt tgcattagag atctgcctcc ttaaatacga cctgaccatt
    54361 ttcaaaacga tccaagcgag caagtgatag gacagggtag cctgcttttt caagcaaatc
    54421 acgaccatct tggaaggatt tctcaatcac gataccgata gcttggactg tggcaccggc
    54481 ctgttcgatg atttgaatca agcctttagc agcttggcca ttagcaagga aatcgtcgat
    54541 aatcaaaacc ttgtcctctg gtgagaggaa ttttccagcg atagaaacag tgctggtcac
    54601 ctgcttggta aaggagtaga cttgagcagt taagatgcct tcgttcatgg tgatgttctt
    54661 agcttttttg gcgaaaatca tgggaacgtt taaggcttca gctgtaaaaa cggctggggc
    54721 aatacccgac gcttcaatgg ttacgacctt ggtaatgcca gtagcagcaa atttttccgc
    54781 aaaaacctta ccaatctctc gcatcaagct aaagtcaact tggtgggtta aaaaggaatc
    54841 taccttgagg atgttatcac ccaagatatg cccatccttg aggatgcgct cttctaataa
    54901 tttcataaga cctcctaaag tctaaaagtt aatttacttg ttgtttaaat atttctatag
    54961 tgatcccttt tgctaatact atatatttga taaaactatt acgagcgaag cgagtcttat
    55021 caaatatttc ccgttgtagt ggtatcatag acaataatct tgttattgtc tatgacggga
    55081 tttttgagag taaaatagtt cggggaacta ttttagccta agcctagaaa tgaaagagct
    55141 aggggctcaa aaattaggga tgaaattccc tggattcctg aaattattca caggataatt
    55201 tcacctcccg tccgcactaa ttaagggaaa tattaaaaat attcaaaaaa gacctactta
    55261 atctctaagt aagtccccta aatagacatg gcaaaaacgg ccatatctca ctgctgactt
    55321 acttattgtt aggtgttccg gcaccttgta gaaacgtcgt gccaattcac gacataaaca
    55381 agtaaaacga tattcaattt taaataggct tgagccaatg tttttatttt acactaaata
    55441 actttagaaa tcaactattt tgttagtgtt ttggtttaaa aagcgaacaa aaataagaga
    55501 gggtgaacaa aaactccatt gtaagctaac atttatacta aatgaaaatc aaagagcaaa
    55561 ctaggaagct atccacaacc tcaaaacact gttttgaggt tgtggataga attgacagag
    55621 tcagtatcat atacctacgg taaggcgacg ttgacgtggc ttgaagagat tttcgaagag
    55681 tattagaaga tttttccatc ataaaaggca tactatcaag tttttagaca cctgacaata
    55741 tgcctttttc taactttaaa gacttttccc aatttttatt attctactcg ctaaatctta
    55801 aaaaatagcc atctggatcc aaaactgcaa atttatgagg atagatatag ggatcactga
    55861 cacgaaactt tcttttggtc aagagacgat aaataggata gtttgcctcc atcacttttt
    55921 gatagagttt tggaacatcc tttatgccaa aggagagatt gactccacga ccaaaggggt
    55981 aggtcagttc agctagttga tcctttgttc cctcctctaa cattagttga cactcttcaa
    56041 gagaaagaga aagttttctt ctggacgtta gtattcaatc ctaaaaccca gtaaaccaca
    56101 gtagaaggac cgggactgtt cgatattcga tacaagaaac tcgggaatga ccgcattgta
    56161 gtccatatag aaaatcctta caagtcaatt tccaagacaa tcggtgtatg gtcttggcga
    56221 gcacctgagt caatcatatc agatttagtg accttgtcag cgatacggtt acttgtgagc
    56281 cagtagtcga ttctccagcc tgtattgttg attttagaag ttttgctgcg ttgtgcccac
    56341 caagtgtagc gttcaggaac atcgccatga acatggcgga aggtgtctgt aaatccagtt
    56401 gccaaaaggt tggtaaatcc agcacgttcc tcgtcagtaa atccaggtga acggcggttg
    56461 ctagcaggat ttgcaaggtc gatttcattg tgggctacgt tgtagtcacc ggtcgcaagg
    56521 actggttttt ctttgtctag ttcagccaaa tactcagcat atttaacatc ccagacttgg
    56581 cgttcttcca agcgtttgag accgtcacca gcgtttggag tgtaaacttg ggttacgaaa
    56641 aatgcatcaa attctagagt gatgatacgg ccttccaagt ccatggtaga aggggcaccg
    56701 atttctggaa aactgatcgt aggcgtaagt tctttcttat aaaggaacat ggttccagca
    56761 tagcctttac gggcaggctc ttgggaagag cgccatgtgt tttcgtagcc tgggaagagt
    56821 tcttctaaaa tttccacgtg tttctttgta ggtcctttgg cagaaagctt ggtttcttgg
    56881 atagcaatga tatcagcatt ttcagcgacc aaggtttgta ggacttcttg ggacaatttg
    56941 gcacgagctg agtcactagt tagggcagcg tttagggaat caatattcca tgagataagt
    57001 ttcataaagt tacctttttc attcagatta tagattttat tataccaaaa aaagatctat
    57061 ttccccaacg tatggtttga aaaattactc tctttcgttt ataattaaga atgattttat
    57121 gaaagggagt gaaaatatat gaaattctac tcttatgact atgtactcag ccaaatcggt
    57181 cagcaaaatg gtatcatggt tggctttggg attgttctat tagctgtgac agtttttttt
    57241 gctttcaagg cataccatga taaaaaggga accgaatttc gtgagttggt catgatttca
    57301 gctctggcct tatttagctc tgcttttggt cagcatcacg acttatcaaa acaatcaagt
    57361 ttctaacaat aaatttcaaa cttcacttca tttcatcgag gttgtttcca aagatttggg
    57421 agtagacaag tcagaagtct atgttaatac ttccacaaac acagatggcg cacttatcaa
    57481 ggtgggagat cgctattatc gtgccctaaa cggaagtgag ccagacaagt acctgttaga
    57541 gaaagtcgaa ttgtataaga cagacgcaat tgaactggtg gatgtgaaca aatgacactt
    57601 aattatatcg aaattttaat caaactggtc ttgactctca aatggctcaa caacaatgtt
    57661 cactttgtga aacgtttgat tgatggtaag ccaactctcc ttatcaaaaa tgggaatatt
    57721 gacccagaag cctgtcgttc agttggtttg tctgcatcgg atgtagccct caaacttcgt
    57781 agccaaggga ttttccagat gaagcaagtc aaacgagctg tgcaagagca aaatgggcaa
    57841 cttatcgttg tgcaaatggg agatgaaaat cctaagtatc cagttgtgac tgacggtgtg
    57901 attcaagtag atgtcttgga atcgattggt cgtagcgaag agtggttgct tgataacctc
    57961 agtaaacaag ggcatgacaa tgtagccaat atctttattg ctgaatatga caagggtgct
    58021 gttacagtcg taacttatga aaaagaaaaa cctggggtct tgtactcttc gaaaatctct
    58081 tcaaaccgcg tcaacgtcgc cttgccgtat gtaggttact gacttcgtca gttctatcta
    58141 caacctcaaa gcagtgcttt gagcagcctg cggctagttt cctagtttgc tctttgattt
    58201 tcattgagta ttggcctcag gtttccattt gcaatcagaa agggatttta tgtccattat
    58261 tcaaaaactt tggtggtttt tcaagttaga aaaacgccgt tatctagtcg gaattgtggc
    58321 cctggtcttg gtttccgtcc tcaatctcat tcctcctatg gttatggggc gggttattga
    58381 tgccatcaca tcggggcaat taacccagca ggacctcctt cttagcctat tttacttgct
    58441 acttgcagcc tttggtatgt actatttgcg ctatgtgtgg cgtatgtata tccttgggac
    58501 ctcttattgc ttgggacaga tcatgcggtc tcgcttgttt aagcatttca caaaaatgtc
    58561 gtcagccttt tatcaaacct atcggacggg tgatctgatg gcacacgcaa ccaatgatat
    58621 caatgccttg actcgtttag caggtggcgg tgtcatgtct gcggtggatg cctctatcac
    58681 ggctctggtg actttgttga ccatgctctt tagcatctca tggcagatga ctcttgttgc
    58741 cattctcccc ctacctttca tggcctatgc gactagtcgc ctagggagaa agactcataa
    58801 ggcctttggc gaatcccaag ctgctttttc tgaactcaat aacaaggtac aggagtccgt
    58861 atcaggtatc aaagtgacca agtctttcgg ttatcaggca gacgagttga agtcttttca
    58921 ggcagtcaat gaattaacct tccaaaagaa cctgcaaacc atgaaatatg atagtctctt
    58981 tgaccctatg gttctcttgt ttgttggttc gtcctatgtt ttaacgcttt tggttggctc
    59041 cttggtggtt caggaagggc agattacagt tgggaatcta gtcaccttta tcagctattt
    59101 ggatatgctg gtctggcctc ttatggccat cggcttcctc tttaatacta ctcagcgagg
    59161 gaaggtttct taccagcgga ttgaaaatct tttgtctcag gaatctcctg tacaagaccc
    59221 ggagtttcct ctggatggta ttgaaaatgg gcgtttggag tatgccattg acagctttgc
    59281 ttttgaaaat gaggaaacac tgacggatat tcactttagt ttggcaaaag ggcaaacact
    59341 gggcttggtt gggcagacag gctctgggaa aacgtcctta atcaagctcc tcttgcgtga
    59401 atacgatgtg gataagggcg ccatttatct aaacggtcac gatattcggg actatcgtct
    59461 gacagacctt cgcagtctca tgggctatgt tcctcaggac cagtttcttt ttgcgacttc
    59521 aatcctagac aatatccgct ttggcaatcc taacttgccc ctttcagcgg tcgaggaagc
    59581 tactaagcta gcccgagttt accaagatat tgtagacatg cctcaaggat ttgatacgct
    59641 gattggtgaa aaaggagtca gtctttctgg tggtcaaaag caacggttgg ctatgagtcg
    59701 ggctatgatt ttagaccctg atatcttgat tttggatgat tccttatccg ccgtagatgc
    59761 caagacagag tatgcgatta tcgacaacct caaggagacg cgaaaggaca agacaaccat
    59821 tatcactgcc catcgcctga gtgcagttgt ccatgcagat ttgattttag tcctgcaaaa
    59881 tggtcaaatt atcgaacgag gcaggcacga agacttgcta gctttggatg gctggtatgc
    59941 ccaaacctac cagtctcagc agctggaaat gaagggagaa gaagatgcag aataaacaag
    60001 aacaatggac tgtattgaag cgcttgatgt cctatctcaa gccttatgga ctccttacct
    60061 ttttggcact cagttttctc ctagcgacga cggtcattaa aagtgtcatt ccccttgtgg
    60121 cttcccactt tatcgaccag tatctcagca atcttaacca actagccgtg accgttttgc
    60181 tggtctacta tggtctctac atcctacaaa ctgtagttca gtatgtcggc aatcttctct
    60241 ttgcgcgcgt gtcttacagt attgttaggg atattcgtcg ggatgccttt gccaatatgg
    60301 agaaactggg catgtcttac tttgacaaga cgccagcagg ttctatcgtt tctcgtttga
    60361 ccaacgatac cgagacgatt agtgatatgt tttctgggat tttatccagc tttatctcag
    60421 cagtttttat ctttctgaca accctttata ccatgttggt gctggatttt cgtttgacgg
    60481 ctttagtctt gctctttctc cccttgattt tccttttggt caatctctat cgaaaaaagt
    60541 cagtgaaaat catcgagaaa accagaagtc tcttgtcaga tatcaatagt aagctggcag
    60601 agaatatcga gggaatcagg attattcagg cttttaatca agagaagcgc ctgcaggcag
    60661 aatttgatga aatcaaccaa gagcacttgg cctatgccaa ccgttctgta gccttggatg
    60721 ccctcttttt gagacctgcc atgagtttgt tgaaacttct aggttatgct gtcttgatga
    60781 cctattttgg ctatcgtggt ctttctatcg ggataacggc cgggaccatg tatgctttta
    60841 tccagtacat caaccgcctc tttgaccctt tgattgaggt gacgcaaaac ttttcaacac
    60901 tgcaaacgtc tatggtttct gcaggccgtg tctttgcctt aatcgatgag aggacctatg
    60961 agccccttca agaaaatggg caagccaaag tcaaagaagg caatatccgt tttgaacatg
    61021 tgtgtttctc gtatgacggt aaacatccga ttctggatga catttctttc tctgttaata
    61081 agggtgaaac cattgccttt gtaggtcata caggttcagg gaaatcgtct attatcaatg
    61141 tcctcatgcg cttttatgaa ttccagtcag ggagagttct cttggatgat gtggatatca
    61201 gggatttcag tcaagaagag ctgagaaaaa acatcggttt ggttttacag gaacccttcc
    61261 tctatcatgg aactattaag tccaatatcg ccatgtacca agaaatcagt gatgagcagg
    61321 ttcaggctgc ggcagccttt gtggatgcag attcctttat tcaagaactt cctcaggggt
    61381 acgactcccc tgtttccgag cgtggttcga gcttctctac tgggcagcgc cagcttcttg
    61441 cctttgctag aacagtcgcc agccagccta aaatcctgat tttggatgaa gcgacagcca
    61501 atattgactc tgaaacagaa agtttggttc aagcttctct ggcgaagatg agacagggcc
    61561 gaacaactat tgctatcgct caccgccttt ctactattca agacgccaac tgcatctatg
    61621 tcttggataa gggacgcatt atcgagagtg gaacccatga ggaactcttg actctgggag
    61681 gaacctatca caagatgtat agtttgcagg caggggccat ggcctatact ctttgaaaat
    61741 ctctttaaac catgtcagct ttatctgcaa tctcaaagct gtactttgat tttcattgag
    61801 tactagaagg aaatccttca aattacagat ttctttcacc gccttttcca ttttgtggta
    61861 taatgaaaaa tgttgacaaa tagtataata aaaacaaagg agaacagcat gctgaaatgg
    61921 gaagacttgc ctgtggaaat gaaatcaagc gaggttgagt cttactacca gcttgtctct
    61981 aaaaggaagg gttcgctgat tttcaagcgt tgcttggact gggttttggc cttggtctta
    62041 ctggttctaa cttctcccat ctttctcatc ttgagcattt ggatcaagtt ggatagcaag
    62101 gggccagtga tttacaagca agagcgtgtg acccagtaca accgtcggtt caagatttgg
    62161 aagttccgta ccatggtgac ggatgcggat aaaaaaggaa gtctggtgac ttctgctaac
    62221 gatagccgta ttaccaaggt tggaaatttc atccgacgtg tccgtttgga cgaactgcct
    62281 cagttggtca atgtccttaa aggtgagatg tcctttgtcg gtacacgacc tgaagtgcca
    62341 cgttatacag agcagtatag ccctgaaatg atggcaacct tgctcttgca agcaggaatt
    62401 acctctccag ccagcatcaa ctacaaggat gaggacacca tcatcagtca aatgacggag
    62461 aaaggtctgt cagttgatca ggcctatgtg gagcatgttc ttcctgaaaa gatgcgctat
    62521 aacctcgcct atctccgaga gtttagtttc tttggggaca tcaaaatcat gtttcaaacc
    62581 gtgtttgagg tactaaaata aagtagtcat aagaaaatga gtacagataa aaggagcaaa
    62641 tcaatgccaa attacaatat tccattttca ccgcctgata tcacagaagc agaaattgct
    62701 gaagtagcgg ataccctgcg ttctggttgg atcacaacag gtcctaaaac aaaagaactg
    62761 gagcgccgct tgtctcttta cacacagaca cctaagactg tttgtctcaa ctctgcgaca
    62821 gccgctctgg agttgatttt acgcgttttg gaagtgggac ctggtgatga agtcatcgtt
    62881 ccagccatga cctatacggc ttcatgtagt gtcattacgc acgtgggagc aacccctgtc
    62941 atggtggata tccaagcaga tacgtttgag atggactatg acctgcttga gcaagctatc
    63001 actgagaaaa ctaaggtgat tatcccagta gagctcgcag ggattgtttg cgattatgac
    63061 cgtttgttcc aagtcgtgga gaaaaaacgt gacttcttta ccgcttcaag caagtggcaa
    63121 aaggccttta accgtattgt cattgtctct gatagtgccc acgctttggg atctacttat
    63181 aaaggacaac cttctggttc tatcgctgat tttacttcct tctcattcca tgctgttaag
    63241 aactttacaa cggcagaagg tggaagtgcg acttggaaag ccaatccagt gattgatgac
    63301 gaagagatgt acaaggaatt ccaaatcctt tcccttcacg ggcaaactaa ggatgctctt
    63361 gccaagatgc aactggggtc atgggaatac gatatcgtta caccagccta taagtgcaac
    63421 atgaccgata tcatggcttc acttggtttg gtacaattgg accgctatcc aagtttgttg
    63481 caacgccgta aggacattgt ggaccgctat gatagtggtt ttgcaggttc tcgcatccat
    63541 cctttggcac acaagactga aactgtcgaa tcttcacgcc acctctacat cacccgtgta
    63601 gaaggagcaa gcctagaaga acgcaacctc atcatccaag aattggctaa agcaggaatt
    63661 gcaagtaatg ttcactacaa accgcttcct ctcttgacag cctataagaa tcttggattt
    63721 gatatgacga actatcctaa ggcctatgcc ttctttgaga atgaaattac cctccctctt
    63781 catactaaat taagcgatga agaagtagac tatatcattg agactttcaa aacagtttct
    63841 gaaaaagtgc taactttatc aaaaaaatga caaactacag tcaagcgaaa gtgatcctgt
    63901 ccctaaaaag tctaattgag tgtaaaaact gttgttttca attgataata gtttacacct
    63961 gtagttgagg cctctttctc ctcagagaga gaatttttat aggattttcc tttcttgtgg
    64021 gagtcccgtg gtttgaaata agatgtgagc aatttggtat agcatttaga atccttacta
    64081 gacatcattt agaaaatcta gtgtcttgtt ctagttttca attcacccta ttttttgaaa
    64141 gacgtgagtt tccatgagtg agattgtgga aactagcgtc ttttttttgt tttcagaata
    64201 ttgttcaaag ttttgtgcct gtctttcatg ttctagtcat tcttttgcat gatagaattt
    64261 atagcatgtt gatattataa taacgcaaat atcccatatg tttagtgatg cttgctatac
    64321 atcattagat ctcctgcgag acaatctata aaacacttgt ctacgattac ctatatgccc
    64381 tattccagta ttttagaagc actgcatcta tttttatcga ggttaaatct agcttttata
    64441 gaaggtctat ttaagaaata tattgtagtg ttttagtttc aatccgccat atgagcgata
    64501 ttcaggtaaa tatccctggc gaatgcttgt atgacaaggt atttgttctt tcatttataa
    64561 tttacaacat atcaacaaat ttaaatatag taaatgggat attttatatt caagctaaga
    64621 aagatagcat cacttttgaa tggaaggcta aagagcaaac taggaagttg gccatagata
    64681 gctcaaaacc ctgctttgag gttgtagata tagtaaaatg aaacaagaat aggacaaatt
    64741 gatcgggaca gttaaatcga tttctaacaa tgttttagaa gtagaggtgt actattatag
    64801 tttcagtcta ctatagaact gaccaagtca gtaacctaga cttagggcaa ggcggcactg
    64861 acctagtttg aagagatttc cgaagagtat aaattttaat attttcttgt gttattcctt
    64921 gacaattcaa tttggaaaat atatgataaa gataatgaca gcggtgtcat tctatctatt
    64981 ttaagaaaag taataatcaa ttgttaaaaa tagtaaaaaa attggaggtt ctgatgaaat
    65041 attttgttcc taatgaggta ttcagtattc gtaaattaaa ggtggggact tgctcggtac
    65101 tattggcaat ttcaattttg ggaagccaag gtattttatc ggatgaagtt gttactagtt
    65161 cttcaccgat ggctacaaaa gagtcttcta atgcaattac taatgattta gataattcac
    65221 caactgttaa tcagaatcgt tctgctgaaa tgattgcctc taattcaacc actaatggtt
    65281 tagataattc gttaagtgtt aatagtatca gctctaatgg tactattcgt tccaattcac
    65341 aattagacaa cagaacagtt gaatctacag taacatctac taatgaaaat aagagttata
    65401 aggaagatgt tataagtgac agaattatca aaaaagaatt tgaagatact gctttaagtg
    65461 taaaagatta tggtgcggta ggtgatggga ttcatgatga tcgacaagca attcaagatg
    65521 caatagatgc tgcagctcaa gggctaggtg gaggaaatgt atattttcct gaaggaactt
    65581 atttagtaaa agaaattgtt tttttaaaaa gtcatacaca cttagaattg aatgagaaag
    65641 ctacaattct aaatggtata aatattaaga atcacccttc cattgttttt atgacaggtt
    65701 tatttacgga tgatggtgcg caagtagaat ggggcccaac agaagatatt agttattctg
    65761 gtggtacgat tgatatgaac ggtgctttga atgaagaagg aactaaagca aaaaatctac
    65821 cacttataaa ttcttcaggt gcatttgcta ttgggaattc aaataacgta actataaaaa
    65881 atgtaacatt caaggatagt tatcaagggc atgctattca aattgcaggt tcgaaaaatg
    65941 tattagttga taattctcgt tttcttgggc aagccttacc caaaacgatg aaggatgggc
    66001 aaatcataag taaggagagc attcagattg aaccattaac tagaaaaggt tttccttatg
    66061 ccttgaatga tgatgggaaa aaatctgaaa atgtgactat tcaaaattcc tattttggca
    66121 aaagtgataa atctggggaa ttagtaacag caattggcac acactatcaa acattgtcga
    66181 cacagaaccc ctctaatatt aaaattttaa ataatcattt tgataacatg atgtatgcag
    66241 gtgtacgttt tacaggattc actgatgtat taatcaaagg aaatcgcttt gataagaaag
    66301 ttaaaggaga gagtgtacat tatcgagaaa gcggagcagc tttagtaaat gcttatagct
    66361 ataaaaacac taaagaccta ttagatttaa ataaacaggt ggttatcgcc gaaaatatat
    66421 ttaatattgc cgatcctaaa acaaaagcga tacgagttgc aaaagatagt gcagaatatt
    66481 taggaaaagt atcagatatt actgtaacaa aaaatgtaat taataataat tctaaggaaa
    66541 cagaacaacc aaatattgaa ttattacgag ttagtgataa tttagtagtg tcagagaata
    66601 gtatattcgg tggtaaagaa ggaattgtta ttgaggattc aaagggtaaa ataaccgttt
    66661 taaataacca attttataat ttatccggta agtatatatc attcatcaaa tctaatgcaa
    66721 acgggaaaga acctgttata cgtgatagcg atggtaattt caatattgta acggagaatg
    66781 ggctttacaa aattgtaaca aataatttaa gtgataaaaa cgaaaaagaa aaaaacaaag
    66841 aggaaaaaca atctaattca aataatgtaa ttgatagtaa ccagaagaac ggagagttta
    66901 actcaagtaa agataataga caaatgaatg acaagatcga caataaacaa gataataaga
    66961 cagaagaagt aaactataaa atagttggag atggcagaga aactgaaaat catattaata
    67021 aatctaaaga aatagtagat gtaaaacaaa aattaccaaa gactggttcg aacaagatta
    67081 tggaactatt cttaacagtg acaggaattg gtttactttt gacactaaaa gggttgaagt
    67141 attatggtaa agataaataa aatttgttcg atacaaggaa gttccgtaga aaatgaggat
    67201 attgtaggtt cacaaaatca gtatttttgg attattggtg gagctacaga tttatataat
    67261 tctaaagagg agataggtta ttcagtctca gaagttgtac atattttatc agaaagtttg
    67321 tcggttaatt gtaaagaatc aaaaactctt aaacaaatat ttgaaactgc tttactcgag
    67381 gttaaagatg aaatcggttt aaactcatat gaattaacag agtataataa aatgaaataa
    67441 taataggaca aatcaatc
//
LOCUS       DAVKBK010000006        64748 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVKBK010000006 DAVKBK010000000
VERSION     DAVKBK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64748
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.006"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(19..1977)
                     /gene="ftsH"
                     /locus_tag="VWX69_000382"
     CDS             complement(19..1977)
                     /gene="ftsH"
                     /locus_tag="VWX69_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU9191787.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAHHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1993..2535)
                     /gene="hpt"
                     /locus_tag="VWX69_000383"
     CDS             complement(1993..2535)
                     /gene="hpt"
                     /locus_tag="VWX69_000383"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU9191788.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2539..3816)
                     /gene="tilS"
                     /locus_tag="VWX69_000384"
     CDS             complement(2539..3816)
                     /gene="tilS"
                     /locus_tag="VWX69_000384"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU9191789.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3813..5081)
                     /locus_tag="VWX69_000385"
     CDS             complement(3813..5081)
                     /locus_tag="VWX69_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU9191790.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5201..5569)
                     /locus_tag="VWX69_000386"
     CDS             complement(5201..5569)
                     /locus_tag="VWX69_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU9191791.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5562..5828)
                     /locus_tag="VWX69_000387"
     CDS             complement(5562..5828)
                     /locus_tag="VWX69_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU9191792.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5886..9395)
                     /gene="mfd"
                     /locus_tag="VWX69_000388"
     CDS             complement(5886..9395)
                     /gene="mfd"
                     /locus_tag="VWX69_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU9191793.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIVASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9396..9965)
                     /locus_tag="VWX69_000389"
     CDS             complement(9396..9965)
                     /locus_tag="VWX69_000389"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU9191794.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSIDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10037..11152)
                     /gene="ychF"
                     /locus_tag="VWX69_000390"
     CDS             complement(10037..11152)
                     /gene="ychF"
                     /locus_tag="VWX69_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU9191795.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11236..11430)
                     /locus_tag="VWX69_000391"
     CDS             complement(11236..11430)
                     /locus_tag="VWX69_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU9191796.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEVTRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11495..12631)
                     /gene="dnaN"
                     /locus_tag="VWX69_000392"
     CDS             complement(11495..12631)
                     /gene="dnaN"
                     /locus_tag="VWX69_000392"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU9191797.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12790..14151)
                     /gene="dnaA"
                     /locus_tag="VWX69_000393"
     CDS             complement(12790..14151)
                     /gene="dnaA"
                     /locus_tag="VWX69_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU9191798.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14364..15122)
                     /locus_tag="VWX69_000394"
     CDS             complement(14364..15122)
                     /locus_tag="VWX69_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU9191799.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15180..16361)
                     /locus_tag="VWX69_000395"
     CDS             complement(15180..16361)
                     /locus_tag="VWX69_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU9191800.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16544..17023
                     /gene="rlmH"
                     /locus_tag="VWX69_000396"
     CDS             16544..17023
                     /gene="rlmH"
                     /locus_tag="VWX69_000396"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU9191801.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17067..17140
                     /locus_tag="VWX69_000397"
     tRNA            17067..17140
                     /locus_tag="VWX69_000397"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17101..17103,aa:Arg,seq:tct)
     gene            17305..17430
                     /gene="comC"
                     /locus_tag="VWX69_000398"
     CDS             17305..17430
                     /gene="comC"
                     /locus_tag="VWX69_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU9191802.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIKGGEMRISRIILDFLFLRKK"
     gene            17451..18776
                     /locus_tag="VWX69_000399"
     CDS             17451..18776
                     /locus_tag="VWX69_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9191803.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYIFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     FKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVMVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18773..19525
                     /locus_tag="VWX69_000400"
     CDS             18773..19525
                     /locus_tag="VWX69_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9191804.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19577..19648
                     /locus_tag="VWX69_000401"
     tRNA            19577..19648
                     /locus_tag="VWX69_000401"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19610..19612,aa:Glu,seq:ttc)
     gene            19654..19727
                     /locus_tag="VWX69_000402"
     tRNA            19654..19727
                     /locus_tag="VWX69_000402"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19688..19690,aa:Asn,seq:gtt)
     gene            complement(19768..20310)
                     /locus_tag="VWX69_000403"
     CDS             complement(19768..20310)
                     /locus_tag="VWX69_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9191805.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDVIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSIDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20489..21256
                     /locus_tag="VWX69_000404"
     CDS             20489..21256
                     /locus_tag="VWX69_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU9191806.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDSYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21341..21679
                     /locus_tag="VWX69_000405"
     CDS             21341..21679
                     /locus_tag="VWX69_000405"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191807.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            21707..22021
                     /locus_tag="VWX69_000406"
     CDS             21707..22021
                     /locus_tag="VWX69_000406"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU9191808.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22122..24674)
                     /locus_tag="VWX69_000407"
     CDS             complement(22122..24674)
                     /locus_tag="VWX69_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU9191809.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24736..26358)
                     /locus_tag="VWX69_000408"
     CDS             complement(24736..26358)
                     /locus_tag="VWX69_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9191810.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26564..27589
                     /gene="trpS"
                     /locus_tag="VWX69_000409"
     CDS             26564..27589
                     /gene="trpS"
                     /locus_tag="VWX69_000409"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU9191811.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27741..29219
                     /gene="guaB"
                     /locus_tag="VWX69_000410"
     CDS             27741..29219
                     /gene="guaB"
                     /locus_tag="VWX69_000410"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU9191812.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29270..30367)
                     /gene="recF"
                     /locus_tag="VWX69_000411"
     CDS             complement(29270..30367)
                     /gene="recF"
                     /locus_tag="VWX69_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU9191813.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30370..30738)
                     /gene="yaaA"
                     /locus_tag="VWX69_000412"
     CDS             complement(30370..30738)
                     /gene="yaaA"
                     /locus_tag="VWX69_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU9191814.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30897..32147
                     /locus_tag="VWX69_000413"
     CDS             30897..32147
                     /locus_tag="VWX69_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9191815.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYCSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32144..33427
                     /locus_tag="VWX69_000414"
     CDS             32144..33427
                     /locus_tag="VWX69_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9191816.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33469..34290
                     /locus_tag="VWX69_000415"
     CDS             33469..34290
                     /locus_tag="VWX69_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9191817.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKISFLPLFYFIFFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34301..34846
                     /gene="pgsA"
                     /locus_tag="VWX69_000416"
     CDS             34301..34846
                     /gene="pgsA"
                     /locus_tag="VWX69_000416"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU9191818.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34843..35670
                     /locus_tag="VWX69_000417"
     CDS             34843..35670
                     /locus_tag="VWX69_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9191819.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35655..36494
                     /locus_tag="VWX69_000418"
     CDS             35655..36494
                     /locus_tag="VWX69_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9191820.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36487..37281
                     /locus_tag="VWX69_000419"
     CDS             36487..37281
                     /locus_tag="VWX69_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9191821.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37340..38158
                     /gene="mreC"
                     /locus_tag="VWX69_000420"
     CDS             37340..38158
                     /gene="mreC"
                     /locus_tag="VWX69_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU9191822.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38158..38652
                     /gene="mreD"
                     /locus_tag="VWX69_000421"
     CDS             38158..38652
                     /gene="mreD"
                     /locus_tag="VWX69_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU9191823.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38746..39924
                     /locus_tag="VWX69_000422"
     CDS             38746..39924
                     /locus_tag="VWX69_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU9191824.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40148..40927
                     /gene="rpsB"
                     /locus_tag="VWX69_000423"
     CDS             40148..40927
                     /gene="rpsB"
                     /locus_tag="VWX69_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU9191825.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41006..42046
                     /locus_tag="VWX69_000424"
     CDS             41006..42046
                     /locus_tag="VWX69_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU9191826.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42292..42615
                     /gene="tnpB"
                     /locus_tag="VWX69_000425"
                     /pseudo
     CDS             42292..42615
                     /gene="tnpB"
                     /locus_tag="VWX69_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(42770..43057)
                     /locus_tag="VWX69_000426"
                     /pseudo
     CDS             complement(42770..43057)
                     /locus_tag="VWX69_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43048..43446
                     /locus_tag="VWX69_000427"
     CDS             43048..43446
                     /locus_tag="VWX69_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9191827.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(43643..44563)
                     /gene="cysK"
                     /locus_tag="VWX69_000428"
     CDS             complement(43643..44563)
                     /gene="cysK"
                     /locus_tag="VWX69_000428"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU9191828.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYNGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(44848..45483)
                     /locus_tag="VWX69_000429"
     CDS             complement(44848..45483)
                     /locus_tag="VWX69_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU9191829.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDNGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45539..46837
                     /locus_tag="VWX69_000430"
     CDS             45539..46837
                     /locus_tag="VWX69_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9191830.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSNLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            46834..47496
                     /locus_tag="VWX69_000431"
     CDS             46834..47496
                     /locus_tag="VWX69_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU9191831.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREEGASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47576..48124
                     /gene="raiA"
                     /locus_tag="VWX69_000432"
     CDS             47576..48124
                     /gene="raiA"
                     /locus_tag="VWX69_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU9191832.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48260..50233
                     /locus_tag="VWX69_000433"
     CDS             48260..50233
                     /locus_tag="VWX69_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU9191833.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50230..50682
                     /gene="rplI"
                     /locus_tag="VWX69_000434"
     CDS             50230..50682
                     /gene="rplI"
                     /locus_tag="VWX69_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU9191834.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            50726..52078
                     /gene="dnaB"
                     /locus_tag="VWX69_000435"
     CDS             50726..52078
                     /gene="dnaB"
                     /locus_tag="VWX69_000435"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU9191835.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52080..52346
                     /locus_tag="VWX69_000436"
     CDS             52080..52346
                     /locus_tag="VWX69_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191836.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            52435..53553
                     /gene="cbpD"
                     /locus_tag="VWX69_000437"
     CDS             52435..53553
                     /gene="cbpD"
                     /locus_tag="VWX69_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU9191837.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSNNSSTV
                     GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGLWYYLGSSGAM
                     KTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      53636..53738
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            53809..54099
                     /locus_tag="VWX69_000438"
     CDS             53809..54099
                     /locus_tag="VWX69_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU9191838.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            54062..54820
                     /locus_tag="VWX69_000439"
     CDS             54062..54820
                     /locus_tag="VWX69_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191839.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            54858..55865
                     /locus_tag="VWX69_000440"
     CDS             54858..55865
                     /locus_tag="VWX69_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9191840.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            55865..56593
                     /locus_tag="VWX69_000441"
     CDS             55865..56593
                     /locus_tag="VWX69_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191841.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            56712..57170
                     /locus_tag="VWX69_000442"
     CDS             56712..57170
                     /locus_tag="VWX69_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU9191842.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            57172..59604
                     /locus_tag="VWX69_000443"
     CDS             57172..59604
                     /locus_tag="VWX69_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9191843.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            59925..60578
                     /gene="rr06"
                     /locus_tag="VWX69_000444"
     CDS             59925..60578
                     /gene="rr06"
                     /locus_tag="VWX69_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU9191844.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            60575..61915
                     /gene="hk06"
                     /locus_tag="VWX69_000445"
     CDS             60575..61915
                     /gene="hk06"
                     /locus_tag="VWX69_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU9191845.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSRLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            61998..62525
                     /locus_tag="VWX69_000446"
     CDS             61998..62525
                     /locus_tag="VWX69_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU9191846.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            62604..64523
                     /gene="pspC"
                     /locus_tag="VWX69_000447"
     CDS             62604..64523
                     /gene="pspC"
                     /locus_tag="VWX69_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEU9191847.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSEN
                     NPTVTSSGQDISKKYADEVKSHLEKILSEIQTNLDRSKHIKTVNLINKLQDIKRTYLY
                     ELNVLEDKSKAELPSKIKAELDAAFEQFKKDTLPTEPGKKVAEAKKKVEEAEKKAKAQ
                     KEEDYRNYPTITYKTLELEIAESDVKVKEAELELVKKEADESRNEGTINQAKAKVESE
                     QAEATRLKKIKTDREKAEEEAKRRADAKEQDESKRRKSRVKRGDLGEPATPDKKENDA
                     KSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEAEKKAKDQKEEDHRNYPTITYKTLEL
                     EIAESDVEVKKAELELVKEEAKGSRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAE
                     EEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEED
                     YARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQYNG
                     SWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYNGSWYYLNSNGAMVTGWLQY
                     NGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNT
                     TVDSYRVNANGEWVN"
BASE COUNT        20322 a        11040 c        12867 g        20519 t
ORIGIN      
        1 ctccagcctc tctcagggtt atttttcgtc attcattttt gactttactt catcatagga
       61 tagtgcatga gattcctctt ctactgcttc aggcatcttt cctgtttcgt aaagagcttt
      121 aatttgtgta ctatccaatg tttcgtattt caataatgct tctgcaatta acttgtgagt
      181 ttcacgattt gactgaataa tttcagcagc tttatttcgt gcctcattta ataatgaacg
      241 aacctcttca tcaatttcat aagctgtttg ttctgaaatt gatttttgag gactctgtgc
      301 accaagcata gcatggtttc cttcatattg tactgggcca agtttttcac tcataccgta
      361 ctctgtaacc attgcacgtg ccatttgtgt cgcttgttca aagtcgtttg aagctcctgt
      421 agtttggaca ttaaagataa tttcttcagc tacacgtcca cccattaagc cagccaattg
      481 ctctttcata tcttctttag atagaagcat ttgatcctct ttaggaagtg caatcatgta
      541 tccgcctgca cggccgcgtg gtacaattgt aaccttatgg acaacgcgag cattcgacaa
      601 gactagacca acaatggtat gtcctgcctc atggtgagca accaattctc gttctttttg
      661 tgaaactgtc ttatctttct tagaaggtcc agcaataact ctatcttctg cttcatcaat
      721 atctgaagca tcaattatcg atttattgcg acgagcagca actaaagctg cttcattcaa
      781 gacattctct aaatcagcac caacaaagcc tggagtttgt tgagccacta atttcaaatc
      841 aacatcttct gctaaaggct tgttcttagc gtgaactttc aagattgctt cacgaccttt
      901 aacatcagga cggccaacca atacttttct atcaaaacgt cctggacgca aaagggcagg
      961 atcaagtaca tctgaacggt ttgtcgcagc gatgacgata atcccttcat ttccctcaaa
     1021 accatccatc tcaatcaaaa gttggttcaa ggtttgttca cgttcgtcat tacctccgcc
     1081 gagaccgact ccacgttgac gtccaacagc atcaatttca tcgataaaga tgatagctgg
     1141 tgctgctttt ttggcatcct caaaaagaga gcgaacacga ctagctccaa ctccgacaaa
     1201 catttctaca aagtcagaac ctgagatact aaagaatgga acacctgctt ctccagcgac
     1261 tgccttagca agcaaagtct tacctgtccc cggaggtccc tccaaaagaa cacctgctgg
     1321 aatacgggct ccaagttttg tgaatcgttt tggatctttt aagaactcaa caacttcaac
     1381 tagttcttgt ttttcttcct cagctccagc aacatctgaa aatcttactt taatatcttc
     1441 tttatttgct gctttagcct tactacgtcc aaaactcatt ggattacggc cattgcctcc
     1501 tcccatattt cccatcatag agaataggaa gaagaataga attccaaatg gcacaatgga
     1561 tacgagtaga ttaatccata taccacttga actttcatgc ttaacagtta cttctgcttt
     1621 atggtcagta gcaagttttt gcaattctga tacggtagta tctgcaggaa gaatagtgct
     1681 ggtaaatttc tctaccttag taacagatgg cgtgaaaaac tgaatacctg ttccttcttt
     1741 acttgtttta ggatttttat agacaccaga aacttcgata acactaccat ttggttggta
     1801 agttaattct tttacattac catcggtaat ttcttgtacc aactcagtat agttgatttg
     1861 ctgacttcct cctgagttat tcccagaata gaaatactgg aatcctgtca caaggaaaaa
     1921 gataaataat aaccatagaa aaggattttt aattaaacca ttattttgtt ttttcattaa
     1981 agattattct ttctaatttg aatacacttc ctctttcaat actccaatat aaggaagatt
     2041 acgataattt tctttgtagt ctaaaccata acctactaca aactcatttg ggatagtaaa
     2101 gcaggtatag tctgcctcaa tttctacaac acgtccttct ggtttatcca acaaggttgc
     2161 aattttaaca gaagctgctt ctctttcttt aaacatatct cgcaaattct tcaaagtttg
     2221 acctgtatca atgatatctt ctacaaatag aacatgtctt cctttgatat cttgagtcac
     2281 atcttgttta atattgataa caccactact tgctgttcca ccatggtagc tagaaaccat
     2341 catgaagtcc atttcaatat gtgtatcaat atgtttgacc aattcagcca taaaaggaat
     2401 agatcctttt aaaatcccaa ctaagattgg attttttcct gcatagtctt tagttaattg
     2461 agcacctagt tttttagctg cttctgtaat ttcatcgtgt gaaacgagga cttttttaat
     2521 atcgttttct aacatttttt acctatctat tttttctata taaagtacag tgttcattat
     2581 atcatttttc gtttttttac tcaaattatt ggtcgcaatt cccaaaattg agacaatttc
     2641 accaaattgc tcaataataa gagcagagtt tctcttttcc atagggattt tcaaatcaat
     2701 aaataaacgt ctgagttttt ttctatgccc attttgaatc aaaacatctc ctgtttttcg
     2761 atgacgaatg tgtatggatg tttcacgtga aacaggtatt tgttgaatta attcaccttc
     2821 taatggaagt ccaaaggaaa ataaatatcc ttgataagct acctgatttt gatagtgtaa
     2881 cacaagttca tcttcctctt catcagcctg cggactgatt ttacaaatct gaaactgttg
     2941 gtactctttt atcaattcat agccattttt aatcggatga cgatactggc ttttagattt
     3001 taaaatctgc tgaacttcag caaactgagc ttttgtaaga ttcaaatctg gaaaacgatt
     3061 cagataagtt tgaagtaaaa ctctttgtgt agactcagag taagaaaata actgctgtaa
     3121 attttccaca ttaatattgt tagataattc agctattgcc aaatcataat ctaaaatttc
     3181 attgccgatg cctaagattg catccctaaa tcgaggattt tctttttcca attctggtaa
     3241 gtaagaattt cgaatacgat ttcgaaaata atgattctcc tgatttgatg tatcttcaaa
     3301 gtgaaaaatt gatggaaagt cttttttctg aaaatgcaag aagggacgaa tgatttctat
     3361 ctctccgact acttgcttct ccttaattcc tgatagatag cgcaagcgag ttcctcgaat
     3421 caagcgcatc aaaatcgttt ccacctgatc atcagcatgg tgggcagtga ctaaagctgt
     3481 cgcacctgtc tttttcatga cctcttgaaa aaaatcataa cgaaaatttc gtgcacgcgc
     3541 ttctgaaaat tctcctgaaa aattgctgat ataaatagga agctctgctt cagcagccaa
     3601 cttccttaat tccttttctt cccaatctga ttcaattctc tgcttatgat tcacatgagc
     3661 tagaatcaat tcaatctcta actctttttg ataagtagac aataccttaa atagaaacat
     3721 ggaatctaat ccaccagaaa gagctagaac cgccttagca tgctttttga aatatccctt
     3781 cttgagaaaa tgatttaaaa aatctggttc cctcatttta gaacctcata aacatccttg
     3841 gctatcttag aaatcgtatc ataatcagaa ttcttagtga aaatagaaag aataaatgga
     3901 gaatctgcat agacaacacc cgtatcatgc ttaaattcat ccgcatctcc aattttatga
     3961 gctactttaa cagaaacacc tttggcaatt cgctgactat caaaatctgt tttagtcaaa
     4021 gactctagca caaatccatt ttgattataa atagcttcca taaacttccc ggccatctta
     4081 gaagaaatca atttttcttt tggatcccaa tcatctccca taatggcaga catcttggat
     4141 ttgaatgtgg catcagattg gtttgaaatg taatatccca atagattatg agctacatta
     4201 tcagattctt ttgatacttt cgtaattaaa tcctttaaag aatattcttt attatcttct
     4261 tttttaggaa gactaccact tccctctggt ttataagaac ctggaaaatc attgactgca
     4321 gatacgtatt ttacagtcgt atctaactga taaagaccct catttatttt ttcttgcgta
     4381 taatagagat aggagagttt caaaacgctg gctgcataca tcttttcatc ttgattgata
     4441 ccagcttctt ttccagtagt cagttgctta acataaatag agaaagaatc tttctgatat
     4501 ttttcagata acatttcttg aactttactc atccgattat cttcttcaga agttgattct
     4561 ttagctaccc atccagcctg atcaatatgt agaaattctc ttccttctac aaacatggtc
     4621 ttgtcgattg atacttgcga ataagctgat aaggatgatt tcacttcttt taaatcataa
     4681 ggactattgt acagtttaaa gtcagattct aaccatgctt tttttattgt tggagttacc
     4741 tctgattgat catataaaaa tcgtttgtcc gcagctataa attgatgatt tgatagctta
     4801 aatactggaa ttccttgttt atttaagcgc cactcggtta tttgaaaact tgttttggga
     4861 gtcaatttcc cagattccac tactaaatct tcattcgcat aaacaggaac ctctccataa
     4921 accatgggag aacttaattt ttctctaaaa taaatactaa agtcagattg tgaaaggtaa
     4981 taaatttctt tcgaagtata gacgacttct ttttctgtgc taacgacttt tgaaatggtc
     5041 aaaaaacttg gtagcaacaa aataattaag aatttacgca ttcttccttt ccttttcttc
     5101 ttgtaaacgc aataattgat ttttatcagc caattcttcc agcttttcat ctgacaaact
     5161 caaaaattgc tctattacgt ctaataaatt ttccatttta tcacctttga agcaagtcag
     5221 gaatcgtata aactttttcc ctcgacttag aataatagta cttcgctcgt gtatatttag
     5281 cagcataatc ttcatctttc aacttggtag caaatgctgt ctccttatcc ttttcatcac
     5341 tcaaagtttg atactgagtt tgcaagtctg ctaattgctg acgtctttgg agtaattgct
     5401 gataactctg cgctaaatta aaagttggca agataaataa tagcataatc aaaatcaata
     5461 cccctcccat aaaacgattc cgtttttgtc gttctttcat caggtagcga cgacgttggt
     5521 attcattttg aataaaagaa ttattcaatt gtacaatatt tttagacatt ttcttctacc
     5581 cgtgtttcac tgataatttc atacattcct gctgcatctt ctttttttgt actatctttc
     5641 atctctagta cttttacaag cagcaactta ttgccaaagc gaatttcaac ttggtcatta
     5701 actttcaagt ccgttgaact tttggccaag attccattaa ccttgattct acctttatct
     5761 gctacttcct ttgcgactgt acgacgcttg ataattcgcg atacttttaa atatttatct
     5821 aatctcatcc ttattacctc aatttattat tgtaccattt ttatctattt tatagaagaa
     5881 aaatatcaaa tggaattttc ttccttaaac tcttttatct ctaataaact ttctccaaaa
     5941 atcagcagac cttctaaaat ttcataatct ttcttatttt ggacatcaaa tacaagctcc
     6001 attaatccct tattctcagc gatgcctgct tttaagttcg ttacggataa agctttaaaa
     6061 taatcttgag ctaaaaacag ccgttgagtg actttttcaa attgaattgt aattttatta
     6121 tcttttcttt ccacacgttg aacaaagacc ttgtccaagt atgatttaac caaaccaatc
     6181 tctaaaagat aggctactac atctgggtat tctccaaaac ggtctatcaa ctcctcttgt
     6241 aactcttcat aattgacacg gttgtcaatt tgacgaattt tcttgtaaat ttcaatctta
     6301 tgtcgttgat cagaaatata agtatcagga agataggcat caatttgcaa aatcaactca
     6361 gcattccctt tggttcttgt gttagcgtta gcattaccgt ttcgtttagc aatagcttcc
     6421 tctaataact gcgaatacaa ttcaaaacca acagaatcaa tgaaaccaga ctgggatttt
     6481 cctaaaagat ttcctgctcc acgaatcgaa agatctcgca ttgcaatctt aaagccagag
     6541 cccaattctg taaatccttt aatcgcttct aatctctttt cagagacttc actgattgat
     6601 ttttctggac gatacatgag ataagcataa gcaatacgat tactacgacc gactcttcct
     6661 cttaactgat ataaggttga caagcccata tggtccgcat tttcaataaa taaagtatta
     6721 gcatttggaa tgtccacccc tgtctcaata atagtagtcg tcaccaagat atcgtattgt
     6781 ccctcaataa agtctaatag agtattttcc aactggactt cactcattcg accatgaaca
     6841 tatccaatcg aagcctccgg aatcaactcc tgtaattctg aaaccttctg aacaattgtg
     6901 tcaactttgt tgtaaagata ataaacttga cctccacgct ccatttcacg caagacagca
     6961 tcacgaatga cactatcatt cttttccaaa acataggtct gaacaggata gcgattagtc
     7021 ggcggagttt caataacaga taaatctctg attcccagca tagacatatg gagggtacga
     7081 gggattggcg tagcggtcaa ggttaggaca tccacttgtt tcttcagttc tttcaaagtt
     7141 tccttatgct tgacaccaaa tcgctgttcc tcatcaataa tcatcaagcc caaatcagca
     7201 aacacaacat cttttgacaa aacacgatgt gttccaatca aaatatcgac ttgaccgttt
     7261 ttcaattttt caagtgttgc agtctgctct tttttacttc taaagcgact caacacatca
     7321 atattaactg caaaattttg gaatcgttcc ttaaaattcg tatagtgctg ttgcgctaaa
     7381 accgtcgtcg gaactagaat gacaacctgt ttgtgatcat tgactgcttt aaaggctgca
     7441 cgcatagcaa cttcagtctt tccaaaacca acatccccaa ctaaaagtcg atccattggc
     7501 tgagaagcct gcatatccct cttgatttcc tcaatactac gaagttgatc atccgtttca
     7561 acataaggga aagcatcatc aaaggcatct tgatcatcat catcagctga gaaagcaaaa
     7621 cccttcaact gactacgttc agagtagagt ttgattaaat catcagctat atcctctacc
     7681 tggttcttaa ccttttgctt ggccttttta aaatgaccgt catttaattt attgagtttt
     7741 ggagctttac catcacttga aatatatttg gacagtagat gaatctgttc cacggggata
     7801 gaaatttgat caccattttg gtattggaca ctgacataat cgcgatgaat tcccttgatt
     7861 tcaatggttt caattcctag atattgacca atcccatgga tatgatggac aacatagtcc
     7921 cctttttcaa gttcattgta atcttttaat ctctctgcat ttgaaacatg ttgtcttcga
     7981 aaacgacgct ttaatttctt ttgaaaaatc tcatgttcag ttatcaataa aatcttttca
     8041 tctacaaaat gaaaaccatg tctgagatta ccctctatta agtttacaga ttctttacag
     8101 atatttgtct tatctctaga atccaattta atctgatatt cctctaacat atcctccaat
     8161 gttttacttc ccattgaatt gctagactgc agaataatgg tgtaatccat ttttttatat
     8221 cgttcaattt cttcttttag aaaagaaaac tgattgaaaa attcctgcat aggatattga
     8281 ttgaattgat aaattttgtc aaatttgaga tttcctaaac ccttttgaag attagagaaa
     8341 aaggtcactg gactttgttt tttatagatt tgttcaatat cagaaaaata ctgcatatca
     8401 gaaaatgctt tactattctg taattcttct gtaaagtact gcgctaagtc tctttcaaag
     8461 acttcatact gattcatcaa tttttgataa tcatcaaaga atattggggt atctttttca
     8521 atataatcaa agacagtcca tgtcttatca tagcacaaag ataaaaactt ccgagagtct
     8581 gcatgacttt gtttttggtg aaaacttgaa agaatttctt ctaggtatga tttcaaaata
     8641 ggtgataaag tttttgaaat ttgtttttct aaagctgact gtcctcgttg ataatccttt
     8701 tctctcaaaa gcatatcact agctggaaag atagtgagtt ctgtcttatt ttctttcgat
     8761 aattgtgttt ctacttcaaa tgacctgata ccatcaattt catcaccaaa aaactcaatt
     8821 cgacaaggtt ctaactggga tatttcaaaa atatctaaaa tatctcctcg aagactaaat
     8881 tcgccctgag tttgtacttg agtaactttt cgatagccat tttcctttaa ctgatggata
     8941 aacgcgtgtt gatcatattc ttcaccaact gagattttta caatactatc tttgaatgca
     9001 ttgggagacg gtaaaatcaa tcgacttgct acgatattac aaactaaaat ccctttctta
     9061 gatgaatcag tcaaaaaacg caaggcttca acccgtgaaa taattttttc ctgtgaagac
     9121 atcaaaaact ccaccatagg agcatcatct accaaaaatg gatagacgag ttcctcaccc
     9181 aagatagata taagatcact aacaagtcct tctgcttctc cataagttga cgtcaataac
     9241 acaatcctat cttctttttc taaactgctt gcaattgcaa gagccttagt agatgttgat
     9301 aaaccaagta ttagttgtct tttcttatct gttaaatttt gatgccattt tttaatctga
     9361 tcattttctg agaataaatc taataaggtc accatttatc cgttatacct ctgcattgtt
     9421 ttctcaaaat ttttctcttg taaatagtag tttacagaat cgtcaacttt gtcaatagac
     9481 tgtaaaatac cgatataatc atccctgtca aacttactca aaacatgatg aacaactgac
     9541 ataccatttt taggtcttcc aattccaatc ttaacacggt taaagacctg agttcctata
     9601 tgttgaataa tagacttgat accattatga ccacctgctg agccttttgc tcttaaacga
     9661 attttcccaa cttccatgtc aagatcatcg taaatgataa gtaaatcgtc aatatccaaa
     9721 ccatagtaag ttaataaagc atgaactgct tttccacttt cattcataaa ggtcgttggt
     9781 ttaaccagat aaattttttc tccatttagg aaaaaggatg ctaggtcagc ttgaaatatc
     9841 ttatcgtgtg taaaagtgac attctgtttc ttcgctagtt gatcaatcaa cataaaacca
     9901 acattgtgtt ttgtttcaaa atatttatcc cctggatttc ccaagcctac aagtaatttg
     9961 gtcatttatt tttcctttca aaagccaaaa gggttggaat tttttttcca acctaattga
    10021 caccatttat taatttttag acattaaagc ggaattccat gatatcgcca tcttgaacga
    10081 tatattcttt tccttcttca cgcaagcgtc cagcttcttt tacggccttt tcagatccgt
    10141 atttcactag atcttcatat gacatggtta ctgcacgaat aaagcctttt tcaaagtctg
    10201 agtggataat accagctgct tgaggagcct tcataccacg tttgaaagtc caagcgcgaa
    10261 cttctttttc accagctgtg aagtaagttc ccaatccaag caagtggtaa gctgcacgcg
    10321 tcaacttatc tacacctgat tctgtcaaac caatggcttc aagaaactct tttttatctt
    10381 catcatccaa ttcagaaatt tcttcctcag cacgcgcaga aataacgact acttcagcat
    10441 tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc gatagagtca ggttctgaaa
    10501 ccacatcctc gtccacatta gctacataaa gaactggttt agtcgtcaaa aggaaaagac
    10561 ctttgacaac cttttgttcc tcatctgtaa attcaatggt acgagctgat ttcccgtctt
    10621 ctaggactgg tttaatcttt tgaagaacat tgaattctgc tactgattct ttatcttttt
    10681 gcgtacgtgc catcttttct acacgcgcat atcgtttgtt cactgattct aagtcagcaa
    10741 gaatcaattc cagattaatt gtatcaatat ctgcaagtgg atctacaaag gcgtcttcac
    10801 gtccttgctc gcgcatcaca ttttcatcat caaaagcacg aactacgtga acaatcgcat
    10861 ctacttcacg aatattggcc aagaatttat tccctagccc ttctcctttt gaagctcctt
    10921 ttacaatccc tgcaatatct gtaaattcaa atgttgtggg aactgtcttt ttaggagtta
    10981 tcatttcagt tagtttttgt aggcgttcat ctggaacttc caccattcca acatttggat
    11041 caatagtcgc aaatgggtag tttgctgcct ctgctcctgc ttttgtaatt gcattaaata
    11101 atgttgattt accaacgttt ggcaaaccaa cgatacctgc tgtcaaagcc atatttctca
    11161 ttctccgttt tcatttcaat ccctaatatt ataacacaaa aagggataaa gtgctaaccc
    11221 tctaactaag ggttctcagt caataatttt attcattttt cgctcaaaat catatcgccc
    11281 catcatgaca acatgctcac aattactgca ttttattttg atatctgctc ctacacgtgt
    11341 aacttcccaa cgattagcct ttttaccagt cgacttgatt gtacaagcgt gtgatttttt
    11401 catctcaaca aaatttccaa cttgatacat actactctcc ttttcttttt cgattatatc
    11461 ataaaagagg cgagccaggc tcaacctctt tcacttaatt tgtacgaact ggtgtaatga
    11521 gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt aaatggacga acagctgaga
    11581 taaagctaat ggtcaccttt tcgctattta aagctttaag agaatcaatc aagtaagttg
    11641 ggttgaaact aatggtcaaa tcttcaccag taacctgatc agtatcgatt tcttcgttta
    11701 ctttaccaac ttctggagag tgaacatggg cgctaacaac cccatcctta atttcaagtt
    11761 tcacagtacc attttgagtc gcacttgata aaagacgggc acgctccatt gactggcgta
    11821 agtttaccac attaaaagta atagtagtgt taaagtctgt tggaatcaag cgatctgtat
    11881 caggatagtt tccttctagg agacgagtat agaagctaat attttcgctt ctaaagagga
    11941 tttggttatt ggcaaagaaa atctctacag tttcgatatc atctgtaaat accgctgaaa
    12001 attcgcgtag agaacggcta ggaattacga catcaaaatc atcactattt ttttcaagag
    12061 tcaatttttt ctggcttagg cgatgagagt ctgttgcaac tgtttttaac tctttgtgtt
    12121 gactcaatac gaagtggaca cctgttaaaa tcggacgact ctcttgtgta cttgcagcaa
    12181 aggctgtttc attaataatt ttcttgagta attttgtttc aagtattaaa ggagtgcttg
    12241 ctgaaatttc ttggattcgt ggatattgtt cgctatcttt tccttttagg gtaatttctg
    12301 atttgccact ggttaaaaca atttgatttt gttcaatttc tttaaaatca agagtcacat
    12361 caggtaaact agatactaca ttgataaaga aagaagcttc aagaaggatc gaacctaaag
    12421 aagtaattaa caaaccagca tcttcatttt tttgagaaat aaaattttca attgaaattt
    12481 gaccatttga accaattaaa gtaatacctt cattggtcac gtcaattttt actgttgata
    12541 aaataggaat ggcattttta gaactaatag ctctcttagt agtatttaat gcttgtagaa
    12601 ataaattttt attaattgaa aaatgaatca tggattctcc tttatttatt tttagtatta
    12661 gaaagataat agtaataata gagtctgtga aatctgtgga aaacagcctt taaacaagtc
    12721 atatcaagtt ttttagcttg tttaaaaaat gtggataaaa aagataaaaa actaaaagtt
    12781 atccacaaat tatttgattt tctttttgat tgattcaatt tctaaacgta aattatcgtc
    12841 ttgatcaatc aaagatttta ttttggcatg ggcatgaatg actgtggtat gatcttttcc
    12901 cccaaattcc ttcccaattt ttggaagact attatctgtt agttctctag ataaatacat
    12961 ggctacttga cgggccaaaa caatattttg aaggcgtcta cttcccttca tttctttgat
    13021 actaacacca taaaagttac caacttcagt ttggatttta tcaattggga tgacgagcat
    13081 ttggctaaca tcttgtttgc gggctctaat ggcttctgca gcaatatcaa tagtgatatc
    13141 cttgattttt tttactctgg caattaaagt gatgtcgttg atggctccct caagatctcg
    13201 aacatttgaa tcaaattgcc cagctaggta ttctagagta tcactttgga aattgtagcc
    13261 taaatgttcc gtcttacttt gtaaaatggc aatacgtgtt tcaaagtcag ggggtgtgat
    13321 agtttgtgtc aatccccaac taaaacgcgt gacaagcctc tcctcgagcc cttctagatg
    13381 ttttggacta cgatcactcg ttaggacaat ctgtttttgc ttgtcatgaa gggcgttaaa
    13441 ggtattgaaa aattcttcct gagttgcgac tttttttccg ctgagtgact gtatatcatc
    13501 gattaacaaa agatcaagac tacgataggt ctttttaaac ttttccattt ccccaagtct
    13561 taggtgatca agaaagtcat taataaagct ttcggcaggg atatatttaa cacgcgcatt
    13621 aggaatattt tttagaattt catttccaat agcgtttaat aagtgagtct taccaaggcc
    13681 tggtcctcca tagataaaaa gagggttata ggtcagagcc aaatcttcag agacagctaa
    13741 agcggctgat acagcccaaa catttccatc cccttgaata aagttatcaa aggtatactt
    13801 ttcttttaat cccgtatctg aataaggaat agatactaac tttggactat agtcataaag
    13861 agttaaattt gtagcttctt caacttgtga gctagtcgta tcttgaggtt tggtgaaaat
    13921 atagtgggga gttatttcag cgtcataaat ttcaaaacca gctactacaa taatatcttt
    13981 tagttgtttt tcccagacca tttccatttc agagcgaggt agaaatatag tggcaacatt
    14041 ttcctctacc ttgatgagtt cagcttgaat agcatagaaa tcatacatgg atcgagtcag
    14101 tctttcttgt gcaaattcta atatacgatt ccaaaattgt ttttctttca atcctttctc
    14161 ctcctttact atttaaaagt ttaatactag agatatttta ccatagatag caagaatttt
    14221 ccacaagctg tgaaaaataa tccacaatgt taccaaactt tatccacagg ttggggataa
    14281 aagaagaaat tattgattta ttaagctttt tatcgaaaaa catagtggat aaccttgtga
    14341 gataaaaaaa taaaagaaca gccttatttc aggctgttga taattctact atattcttct
    14401 tgatttgaaa aagaaataat gatttttcca ctgtcttttt tagatagttt aatttctaca
    14461 tctaatccga gtagttttct taactgtttt tcttcatttt gtatgaaatg attagttttt
    14521 tgctgtttct tttgtttttt ctctgtcaga agagtttcta acttccttac agaaatatct
    14581 tcttctataa tccgttgaaa gaaatagtct tgttgttcct tatttaaccc aactagggaa
    14641 cgcgcatggg cttgtgatag tttgccattt tctacttctg agagaatctg ttctggcaag
    14701 gaaagtaaac gaatggagtt gctgatatat ggacgagact tgcccatctt atctgcaatt
    14761 tcagcatggg tgaatccttt ctctacgaga gattcatagg cgcgtgcttc ttctattggg
    14821 tttaaatttt ctctctgtaa attttcaata atggactgga ccatcatctc ttggtctgaa
    14881 atctgtttaa caacagctgg gatagaccgt agaccagcta aaagtgaagc ccgatagcgt
    14941 ctctctcctg caaggatttc ataaccaata acaggagatt gacgaacaat aatcggttga
    15001 atgaccccat tttctttgat agactgtgct agttcatcta gcttttctct atcaaattct
    15061 tttcggggtt gatagggatt tttttgtata tctgtgatag aaatcatttc aaatttttcc
    15121 atgattctac actaacacat cttttctctt atgtaaagct ttctttacat agatgtcaat
    15181 taagattcta aatcacctga actcttgtta agtttgatag aggtagtttc ttctttcccg
    15241 ttacgatagt aggttatctt aatggtgtct ccgatagaat ggttgtaaag agcactttgt
    15301 aagtctgttg atgaagcaat ctctttgtca tctacttttg taattacatc gtatttttca
    15361 aggtgaccat tggcaggcat attactttgt accgaacgaa caactacacc agatgtaaca
    15421 ttacttggaa tattgagtct tctgatgtcg cttgtactca cattagataa attaaccatc
    15481 tggattccca aagctggacg cgtcactttt ccgttttttt ctaactgttc aataatattg
    15541 atagcatcat ttgcaggaat tgcgaaacca agaccttcta cagatgttcc tccatttgta
    15601 gcaattttac ttgaggtaat tccgataacc tgcccttgaa tattgatcag tgggccgcca
    15661 gagttacctg ggttaatagc agtatcagtt tggatggctt ttgtagaaat agcttgtcca
    15721 tcttccgatt ttaaggatac atttctattg agactggata cgataccttg agtgacagta
    15781 tttgcatatt cagaacctaa cgggctaccg atggcaatag cagtttctcc tacagttaac
    15841 ttactagaat caccaaactc agctactgtt gtcacttttt ctgaagagat ttttacgaca
    15901 gcaatatcag agaaagtgtc agctccgaca atttctccag gtactttagt cccatctgac
    15961 aatcgaatat ctactttgct ggcgccattt ataacgtgat tgttggtgac gatgtaagct
    16021 tctttatcat tctttttata aataactcca gatccttcac tagagattcg ctgagaatct
    16081 gtgtcagtat catcattgcc aaatacgcta ttttgtctgt ttgccgaata agtaataaca
    16141 gaaacaacag catcttttac tttgttaaca gcctgtgttg ttgaattttc gttcttatag
    16201 gcagtttgtg taatagtact attattgtta gagttgttta cactactttt ttgagttagt
    16261 tgagttattg aaaaactacc caaggctcca ctaaaaaagc taatgacgat aacgactaat
    16321 aattgaaacc attttttgta aaatgttttt agatgtttca tatttgcctc catatgtttg
    16381 aattactgaa agtataaact gactagctta attataactt aaacacaaaa gttttacaca
    16441 aactgtggat aactcttttg aaactgtgat tttcttaatt gaaatctatt ttttattttg
    16501 tgaataagat gtgaaaaaat agagaatatg ttagaataga gtcatgaaaa ttaaagttgt
    16561 aacagttggg aaactgaaag aaaagtattt aaaagatggt atcgcagagt attcaaaacg
    16621 aatttctaga tttgctaagt ttgaaatgat tgagttatca gatgaaaaaa caccagataa
    16681 ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa ggtcagagaa ttttatcaaa
    16741 aattgctgac cgtgatttcg ttattgtgtt agccattgaa gggaaaactt tcttctcaga
    16801 agaatttagt aagcagttag aagaaacttc tataaaagga ttttctactc ttacttttat
    16861 tattggggga agtttaggat tgtcatcatc tgtaaaaaat agagccaatc tttctgtcag
    16921 ttttggtcgc ctaaccttgc ctcatcagtt aatgagacta gttcttgttg aacaaatcta
    16981 tcgcgctttt acgattcagc agggattccc ctaccataaa tagaaaattg acttttaatt
    17041 gaatttttgg tagaataatt gtgttaggtc tcatagctca gctggataga gcattcgcct
    17101 tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca atataatagc aaagctggga
    17161 attttcccgg cttttttctt aaaaaagtac actttgggag aaaaaaatga cagttgagag
    17221 aattttatct aaagtgaaat tccattttgt ataatggttt ttgtaagtta gcttacaaga
    17281 aaaaacattt taggagattt tattatgaaa aacacagtta aattggaaca gtttgtagct
    17341 ttgaaggaaa aagacttaca aaatattaaa ggtggggaga tgaggatttc aagaatcatc
    17401 cttgattttc ttttcctacg aaaaaagtaa tgaaataagg agaaagagta atggatttac
    17461 ttggatttgg gacagttatt gttcattttt taattattag tcacagttac cgtttaattt
    17521 gtaaaggtcg aataaataga aaagaattat acatttttgg tgcttataca ttactaactg
    17581 aaatagtact tgaattttcc ttttatcttc tatatttaga taaaataggg attgaaagat
    17641 ttttatttcc tttgggctta tattcctatt ttcgatggat gaaacagtat gagagggata
    17701 gaggactatt cctaagttta ctactatctc ttttatatga gagcactcat aactttctgt
    17761 ccgtaacttt ctcctctata acaggagata attttgtttt acaatatcat ttcccattct
    17821 ttttcgttgt gacggtgtta acctattttg ttacattaaa aatcatttat tatttccatt
    17881 tggaactagc ctattttgac aaggactacc tttatccttt cttgaaaaaa gtattttttg
    17941 ctttactatt gctacatatt gtatctttcg tttcagatat ggtaagtacg attaaacatt
    18001 tgaatagttt tggaagtatt ttgtcatcta ttgtctttat ctctctcctt ttgaccttct
    18061 ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat tgcttttaag cagaagaaat
    18121 ttgaacagaa acatttacag aattacacag atgaaattgt tggtctgtat aatgaaatcc
    18181 gtggttttcg acatgattat gctggaatgc ttgtcagcat gcagatggca attgacagtg
    18241 gtaatttaca ggaaattgac agaatttaca atgaagtttt agtcaaagca aatcataaat
    18301 tgcgttcaga taagtacact tactttgatt tgaacaacat agaagactca gctttacgaa
    18361 gtttggttgc tcagtcaatt gtctatgctc gaaataatgg tgtagagttt acactggaag
    18421 taaaagatac gattaccaag cttccaattg aactattgga tttggttcgt atcatgagcg
    18481 ttttattgaa taatgctgtc gaaggatcgg ctgatagcta taaaaagcag atggaagtag
    18541 cagttattaa gatggaaact gaaacagtta tggtgattca gaattcatgt aaaatgacga
    18601 tgactccttc aggagatcta tttgccttag gattctccac taagggaaga aatcgcggag
    18661 tcggattaaa taatgtgaaa gaactactag ataagtacaa caatattatt ttagaaacag
    18721 agatggaagg cagtacattt agacaaatca ttagatttaa gagggaattt gaatgaaagt
    18781 tttaatttta gaagatgtta ttgaacatca agtgagacta gagagaatat tggatgaaat
    18841 ttcgaaagaa tcgaatattc caatatcata caagacaacg ggaaaagtcc gtgaatttga
    18901 agaatacatt gaaaatgatg aagtaaatca gctttatttc ctagatatcg atattcatgg
    18961 aattgagaaa aagggatttg aagtggctca gctcattcgt cattacaatc cttacgctat
    19021 tattgtcttt atcactagtc gatcagagtt tgcgactcta acctataaat accaggtatc
    19081 agccctagat tttgttgata aggatatcaa tgatgagatg tttaagaaga gaattgagca
    19141 aaatatcttc tacacgaaga gtatgttact tgaaaatgaa gatgttgtag attatttcga
    19201 ctacaattac aagggaaatg atttaaaaat tccttaccat gatattttgt atattgaaac
    19261 aacaggggta tctcataaat tgcgcattat tggtaagaat tttgcaaaag agttttatgg
    19321 taccatgaca gatattcagg aaaaggacaa acatactcag cgattttatt ctcctcacaa
    19381 gtcatttttg gtaaatatag gcaatatcag agaaattgat cgaaaaaact tagaaattgt
    19441 tttctatgaa gaccatcgtt gtcctatttc aagattaaaa attagaaaat taaaagatat
    19501 tttagagaaa aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata
    19561 tctgctacag atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt
    19621 aacacgggtt cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg
    19681 catgactgtt aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg
    19741 gaacacagct gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa
    19801 gtctgttatt tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc
    19861 aaaaagtgca tgagttagat agatgctact atattctaat tcagtggtat ttagattcag
    19921 ttgcataaat cgcttttgta aatctatact gagcatgata tgaagtttat ttcgtaagaa
    19981 attttggatt tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc
    20041 tagatattca aagacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat
    20101 atattcaaat gtatggaata gcttgctttg atagtgctca atcacatcat acttatcctt
    20161 atagtgagta tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga
    20221 aattttatca aatggctgtt ccatcagtaa ttgtaccata gcattttcaa tagttcgctt
    20281 tgtttttaag cgtttgttac tttcttgcat atttcctcct tgtaaacaaa ttagactata
    20341 tgtctaaaaa tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat
    20401 taaaatttta gacaatatgt ttaaaaaagg agaaactaag tttaaagaat ggaaagcaat
    20461 ttaaaaaaaa ccaaccttta ttattgtcat gatcgggatt tctcttattc cagatctgta
    20521 caatatcata tttttgtcat caatgtggga ttcatatggg caattgtctg acttacctgt
    20581 ggcagttgta aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa
    20641 agacatggtg tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga
    20701 ggaaggaaag aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga
    20761 tttatctgaa aaaacaacta cattatccaa tattcaatcg acagcagctt atcaatcatt
    20821 gacaagtgag caacaaactg agataagtga ttctgtatct caaaattcaa ctgatagtat
    20881 tcaatcggct cagtcaattg tagctttagt acaagattta cagggaagtt tagaaaactt
    20941 acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa tctaatcaag tatcacctat
    21001 tacttctact tctttgatag gattgtcaag tggattaaca gagatacaag gagatgttac
    21061 tagcaaatta gttcctgcca gtcagtcgat tgcatcaggt gtaaacgcat atactacagg
    21121 tgttgataaa gtttctcagg gcgcaagtca actaagtgaa aaaaatgcca ccttgacagg
    21181 tagtttggat aaactagttt caggctcaaa caccttgaca caaaaatctt ctagattgac
    21241 agcaggagtt ggttaattac aatcaggatc tgggcaatta gcagacaaat ccagtcagtt
    21301 actttcaggt gcttctccat tagagaatag agctaataaa ttggcagatg gatctgggaa
    21361 actagcagaa ggtggaacaa agttaacttc tggattggaa gatttacaga caggacttgc
    21421 ttctttagga caaggactag gtaatgctag tgatcaactc aaatcagtat caacagaatc
    21481 taaaaatgca gagattttgt caaatccact caatctttca aaaacagaca atgatcaagt
    21541 tcctgtaaat ggaatcgcaa tagctcctta tatgatatca gttgctcttt ttgttgcagc
    21601 aatatcaaca aatatgatat ttgcgaaatt gccttcagga cgtcatccag agagccgttg
    21661 ggcttggttg aaatcttgag ctgaaataaa tggtattata gctgttttgg caggaatttt
    21721 ggtatatgga ggagttcagc ttattggttt aactgctaat catgagatga gaatatttat
    21781 tctcatcatc ctaacaagtt tagtattcat gtctatggtg accactttag caacgtggaa
    21841 tagccgtata ggagcttttt tctcacttat tttgctttta ctacagttag catcaagtgc
    21901 aggtacttat ccacttgctt tgacaaatga tttctttaga tctattaatc cctggttacc
    21961 aatgagctat tcagtttcgg gattacgaca aacaatctct atcaacaagt cattttccta
    22021 gctgtcatac tagttctatt tactagttta ggtatgctag cctatcaaca taagaaaatg
    22081 gaagaagatt aaaaaaatcg accgattaac tggtcgattt tttatgcctt agatgacttt
    22141 cgtctgtgat tatagattcc aaatagtaag agagaagtaa aggaacagat tgctccagta
    22201 ataaaaccat tgggaatgaa ggaaagtgta atagttcctt tccccttggg aatgtcaact
    22261 ttcataaatc cagtttgagc ttgtttaatt tctattttct taccatcttg gtaggcagac
    22321 caacctttgt cataaggaat ggtgaagaaa atagatgtat cttgttggac atcatatgta
    22381 gcaaaaacct tgtttttaga agttgatact gtgacaggtt gttctttaat tttttgaatt
    22441 gcctcggtga aagttttggt atctaaacga tagaaggtag gagattcaaa tgatacttgt
    22501 gaatttccag ggaaactaac attgatattg aaagtttttt tctctttagt atatcctaga
    22561 ttaaagaagg agaagacatt atcagttgta aaagtctttt tttcaccatt tacaaggatg
    22621 tcaaccttct tttgtttatc gttagaaaag tgaaggttta tgaaagagag ataaacttgg
    22681 ctgttttctg gaacttcaat ttgatactgg attgctgcat cttcatttga agaacttgtg
    22741 acactaatca aatcattagt attttctatt ttttctgttt tttcataagg tattggagaa
    22801 aaataatcaa aattgacgtt agcaagttga tttaaaaatg aggcctgatt atccaaggta
    22861 tgttcattga acttgacatc attgtaaaca gattgactag caactgcaat cggaagagag
    22921 tattgatttt catatagggt aagattatct ttttgataga tatctttaaa gccatactta
    22981 tcaataggac tgtctgagat attgtactgg ataccaaata aactatcagc caaaatacta
    23041 ttatttgcat atcggagatt gagattagtc ccagaggatt taaaaccaag tttatctaaa
    23101 gtagagcttg atgaacgatt tcgaacagat gaaaattgag agattccatt gtagttgaat
    23161 ttcatactgt catttcctgt ctgagtttgt agtttttcag tacgagtaaa ttgatttcca
    23221 atatatgttg agaaagattc catagctggg atatctcgac tataagcact tcgagaagca
    23281 aatccccatt ccttagcaat tccgtccatt tgagatgaag catttaaact catttcaacc
    23341 agtataaata aagagattag aatggcaaat agattcacag atataaactt tttgataact
    23401 gcaaggagta aaagagaata gacaaccaaa aattcaagag taagcagaat attcaaatct
    23461 gttaaaaaag aataatgcga ttttagatag atggtagcta aaaatcctgt tactacaaga
    23521 aaaagcgaaa ctaaaaaatt ccagacttta agttctttca gacgctttaa gacttctgct
    23581 gctgtgtaaa ttaacaaggt agagaaaatc caagcatagc gatgtaaaaa catgtttgga
    23641 gtatgcatgc cttgccaaaa taagtcaaga gcttctatgt aaaagcttgc aattagaaat
    23701 gcaaagaata ttacatatat gagtttcacg tgaaacttaa tagatttcag cgtaaaaaat
    23761 aaaatggtca aaataaaggg aaatagtcca acaaaaatca ttgggatggc cccatacttt
    23821 gttgtgtcaa aggaaccaat gaattgctta gcaaagagat caagatacca gctactttca
    23881 gtttgaaact ttgtaacttc agtcaatttt tccccatgtg tctgtaaatc aaatagagtg
    23941 ggaagagtca taatcaaact agccatacca gctaaaaagg agataactat gaaatcaaga
    24001 acagatgatt ttcgagtctt aaagtcccac gaaatttgac agagatacca gaaaataaga
    24061 aacaatactg tcatatatcc aaaataataa ttttgaataa ataagattga cagacttgta
    24121 aagtacaata ggagtttctt ttcagttatc agtagatgta aaccagttat aattaaagga
    24181 atcaagataa aaacatctag ccaggttttt atctctaatt gactgacagt gaaactcatc
    24241 agagcatagg aagtagataa ggctagtttt aaagtctgag ggatagattg aaacaattta
    24301 ttcaaactaa aaaaggttga cagaccaatc aatccaaatt ttaagagagt ggtcagatag
    24361 acagcatctg gcatattcgt tagatcaaaa aagtaaacta gaggcgcgag aaaactaccc
    24421 aagtaataac tagatagggc atagaagttt agccctagac cacttgtaaa ggtgtaaaac
    24481 agactactat ttccatgtag gatatttcgt aaggctacat caaaaataac gtattgatga
    24541 aagccatctc ctaatagagg agagttgtcg ctattccagt agataccttg agatagatat
    24601 actccagaca taatcactac aggaatgatg aaagaaataa aataggttcg atatgttttt
    24661 aaaaatgatt tcatgttacc tcgtagaatg atagaaaact cagttggtta acccaactga
    24721 gttttgaagt tttatttagt ctttccaaag ttctttaact tttgcttgta cttctgcatt
    24781 ttctaggaat tcatcgtagg tttcatcgat acggtcaatg acgccatttt tagataagac
    24841 aatgatatgg ttagccaaag tttgaataaa ctcgtggtca tggctggcaa agatgattga
    24901 ttctttaaag tttttcaatc catcattcaa gcttgagata gattccaagt ccaagtgatt
    24961 tgttggatca tcaagtacaa ggacatttga ttttaagagc atgagttttg aaagcatgac
    25021 acgaactttt tctccccctg acaagacatt tacaggtttg ttaacttcat ctccagagaa
    25081 gagcatacgg ccgaggaaac cacgtaggaa agtattgtca tcatcttctt tacttgcgaa
    25141 ttgacgcaac cagtcaagaa ttgattctcc tcctgcaaaa tcagctgagt tatcttttgg
    25201 taggtaagat tgactagttg taactcccca cttgacagtt ccttcatagt caatatctcc
    25261 catgattgca cgaattaatg cagtcgtttg aatatcattt tgtccaataa gtgctgtctt
    25321 atcatctgga cgcaagatga aactaatatt atccaagata gtttcaccat caatctttac
    25381 agttagattt tctactgtca agagatcatt accaatctca cgttccgctt taaagttgat
    25441 aaatggatat ttacgactag atggtacaat ctcttctagc tcaatcttat caagcatttt
    25501 cttacgtgat gttgcctgcc ttgacttaga agcattggca gagaaacgag caacgaattc
    25561 ttgcaattgt ttaatttttt cttctgcttt agcattacgg tctgctagca atttagcagc
    25621 aagctcagaa gattccttcc agaagtcgta gtttccgaca tagagtttga tttttccaaa
    25681 gtcaaggtcg gccatgtgag tacaaacttt gtttaagaag tgacggtcgt gggatactac
    25741 gataactgtg ttatcaaagt caattaagaa gtcttctaac caagtaatcg attggatatc
    25801 caaaccgtta gtaggctcgt ccaagagaag aacatctggt ttaccaaaaa gtgctttggc
    25861 gaggagaacc tttacttttt caccgttggc caattcgctc atgttttggt agtgtaattc
    25921 ttctggaatg tttaggtttt gaagtagttg agaggcttca ctctctgctt cccaacctcc
    25981 aagttcggca aactctcctt cgagttcggc agcacgaacc ccgtcctcgt ctgagaaatc
    26041 ttccttcatg tagatagcat ctttctcttt catgatgcta taaagttttt catttcccat
    26101 gataacgaca tcaatggcac gttcatcttc gtagtcaaag tgattttgac gaagaacaga
    26161 gagacgttca tctggaccaa gagagatgtg accagtagta ggttcgatat ctccagctaa
    26221 aatttttaaa aaggttgatt ttccggcacc attagcaccg attaatccgt aagtatttcc
    26281 ttctgtaaat ttgatattga catcatcaaa aagtttgcga tcactaaaac gtagtgaaac
    26341 atcagatact gtaagcaata tttttctcct atatgtgtaa tatatttatt ctactagaaa
    26401 atacagaaat attcaaattt ttatttttca attttgtgta aattatattt acagtatcct
    26461 ttacacaaat ctgtaaaaag caaggctgat ttattttgat aaattacggt tatttcatta
    26521 aaaaaatgct ataattgaaa ggactatatc gaaggagaac aaaatgacta aacccattat
    26581 tttaacagga gaccgtccaa caggaaaatt gcatattgga cattatgttg gaagtctcaa
    26641 aaatcgagta ttattacagg aagaggataa gtatgatatg tttgtgttct tggctgacca
    26701 acaagccttg acagatcatg ccaaagatcc tcaaaccatt gtagagtcta tcggaaatgt
    26761 ggctttggat tatcttgcag ttggattgga tccaaataag tcaactattt ttattcaaag
    26821 ccagattcca gagttggctg agttgtctat gtattatatg aatctagttt cgttagcacg
    26881 tttggagcga aatccaacag tcaagacaga gatttctcag aaaggatttg gagaaagcat
    26941 tccgacagga ttcttggtct atccaatcgc tcaagcagct gatatcacag ctttcaaggc
    27001 taattatgtt cctgttggga cagatcagaa accaatgatt gagcaaactc gtgaaattgt
    27061 tcgttctttt aacaatgcat ataactgtga tgtcttggta gagccggaag gtatttatcc
    27121 agaaaatgag agagcagggc gtttgcctgg tttagatgga aatgctaaaa tgtctaaatc
    27181 actaaataat ggtatttatt tagctgatga tgcggatact ttgcgtaaaa aagtaatgag
    27241 tatgtataca gatccagatc atatccgcgt tgaggatcca ggtaagattg agggaaatat
    27301 ggttttccat tatctagatg tttttggtcg tccagaagat gctcaagaaa ttgctgatat
    27361 gaaagaacgt tatcaacgag gtggtcttgg tgatgtgaag accaagcgtt atctacttga
    27421 aatattagaa cgtgaactgg gtcctattcg tgagcgccgt attgaatttg ctaaggatat
    27481 gggagaagtt tataatatga ttcaaaaagg tagtgaaaga gcgcgtgaag ttgcgggtca
    27541 aaccctatct gaggtaaaag gggcaatggg acttcattac tttaactaag tttattttac
    27601 aagaaactat cttttctatc tcgaagaaaa gatagttttt tatttacccc tgtaacattt
    27661 gacaaatttt tatagaatgg tatgatagat acaatataaa aagagtcaag ctcaaaaaga
    27721 aagaaaagag gaaacttcga atgtctaatt gggacactaa atttttgaaa aaaggtttta
    27781 ccttcgatga tgtattgctt attccagctg aaagtcatgt gttgcctaac gatgcagatt
    27841 taacaactaa attggcagat aatttgactt taaatatccc aattattacc gctgccatgg
    27901 acacagttac agagagtcaa atggccattg ctattgctcg tgcaggcggt ctcggagtta
    27961 tccataaaaa catgtcaatt gctcaacaag cagacgaggt tcgtaaggta aaacgttctg
    28021 aaaatggagt tattattgat ccgttcttct tgacgcctga acatacaatt gctgaagcag
    28081 atgagcttat gggtcgttac cgcatcagtg gtgttccagt tgttgaaaca cttgaaaatc
    28141 gtaaattggt tggtattttg acaaaccgag atcttcgttt tatttcagat tataatcaac
    28201 caatttcaaa ccatatgact agtgaaaatc ttgttactgc tcctgtgggt acggatcttg
    28261 caacggctga gagtattctt caagagcatc gtattgaaaa acttccgttg gtcgatgaag
    28321 aaggcagtct ttctggtttg atcactatca aagatattga aaaagttatt gagtttccaa
    28381 atgcggctaa agatgagttt ggtcgtcttc tagttgcagg tgcagtaggt gttacttcag
    28441 atacatttga acgtgcagag gctctttttg aggcaggagc ggatgcgatt gttattgata
    28501 ctgcacatgg tcattctgca ggtgtcttgc gtaaaattgc cgagattcgt gctcatttcc
    28561 cagatcggac tttgattgct ggaaatattg ctactgctga aggtgcacgt gccctttatg
    28621 aagcgggtgt agacgttgtt aaggttggta ttggaccagg ttctatctgt actactcgtg
    28681 tgattgctgg tgttggtgtt ccgcaagtaa cagctatcta cgatgctgca gctgttgcgc
    28741 gcgaatatgg taaaacgatt attgctgacg gtgggatcaa gtattctgga gatattgtaa
    28801 aagcacttgc tgcaggtgga aatgctgtta tgcttggatc tatgtttgct ggaactgatg
    28861 aagctccagg cgaaactgaa atcttccaag gacgtaaatt caagacttac cgtggtatgg
    28921 gatcaattgc tgctatgaag aaaggttcaa gcgaccgtta tttccaaggt tctgtcaatg
    28981 aagcaaacaa gcttgttcca gaaggaattg aaggtcgtgt tgcttataaa ggagcggcag
    29041 ctgatattgt tttccaaatg attggtggta ttcgctctgg tatgggttac tgtggtgcag
    29101 ctaaccttaa agaactacac gataatgctc aatttattga aatgtctggt gctggtttga
    29161 aagaaagcca tcctcatgat gtgcaaatta ctaatgaggc accaaattat tctatgtaaa
    29221 aaacaatgaa aagaactcca gtgaaaacag gagttctttt acaatgttgt caatttccat
    29281 ttacagaagc tttaccatcc tgaatagtga agatacttag attttctggc agattttgaa
    29341 gatggtctaa gcttgttgtt gtgataaagg tttggattga ttgagaaatc gtttctaata
    29401 attttaactg tctagtgttg tcaagttcac tcatcacatc gtcaagcagt aatatcggag
    29461 attctgtggt aatgctttcc attaattcga tttctgctaa ttttatcgag aggacgagac
    29521 tacgatgttg accttggctt ccgaaactag catccatccc atttatataa aaagaaatgt
    29581 catctcgatg aggaccgaca ccagtattct ttttaaataa atctctggat ctactttttt
    29641 ctaaagcaat tttgaaagat tcggataagt tttgtttgtc agttatattg acagaagatt
    29701 gataggatat tgacaactct tcgatctgat tagagagttc aaaatgtttc ttacgcccaa
    29761 atgattctag tttttttatg aaatctaagc ggtgattcat tacacgacat ccataatcaa
    29821 ctagctgatc atctaacaca gaaaggaatg tttcatctat tttttgatct gattttaggt
    29881 aagtgtttct ttgctttagg atgtggttat aattggttaa gtcagataag tagattggct
    29941 taatttgccc aagttccata tcaatgaatt ttcgtcgaat cgaaggtgct cctttaatta
    30001 gttgtaaatc ttcaggagca aataagacaa cattcatgtg tcctacataa tctgaaaggc
    30061 gtgcctgttt taagtgatta acttttgtta cacggccttt ttgtgttagt tcgatttcta
    30121 ggggaatgga tccagttttt ttctgaacga gacctgaaag atgaagttgt tcctcatcaa
    30181 aatgaatgag atttttatct gttcgagttc gatgactacg cgttaaggct aaaaaataga
    30241 tagcctctaa catgtttgtt tttccttgtg cattacgtcc caaaaagaca ttcaatttag
    30301 gattaaagtc tattttcgtt tctttgtaat tacgaaaagt cttgagagat agatgttgta
    30361 gccacatgat tatctaccag ggaatcgtgg agcttgttgg cttttaggtg atgaagcagg
    30421 tttcgatttg tcttttttaa ctcccttatt catctttttg acaagtttag cgatccgttc
    30481 tttttcaact ttatcagctt ggtattcatc ttgttcttca gaagtaggtt gtgtcaacaa
    30541 gatgtcaatg ttcatgtcag ggatgtcaac tttatcgcca atacgaagtt tttttccacg
    30601 acgactctct aattccctat taaagtaaac agaatgttca gagagaaatg atttaatagc
    30661 tcctccgcta tgtgtaattc caagttcttt gagtagtgct tggagggtaa taaattcttc
    30721 aaataatttg tattccataa ttcacctcaa tctttggtat tataccatat tttcctaaaa
    30781 atagtgagag agacagcgag aaatgtaagc gatttttatt tcaaaagtgt tacagggaac
    30841 aagaaaattt caggttttcg tgatataata gaagtctgta tataaggagg taaatcatgg
    30901 agttagtgca tggaatttca acacatttta tccaatcaaa aaagtttaaa acaaacaaaa
    30961 ttaccgtgcg ttttaccgct ccattatccc ttgatacgat tgcaggtcac atgttgagtg
    31021 caagtatgct agagactgct aatcagatgt accccacttc tcaagatttg aggagacact
    31081 tggccagtct atacggtaca gatatgtcaa ccaattgttt cagaagaggg caaagccaca
    31141 ttatagaatt gacatttacc tatgttcgtg atgagttttt aagtaggaaa aacgtgctaa
    31201 cctctcagat tttggaactt gtaaaagaaa ctcttttttc acccgtagta gttgataatg
    31261 ggtttgatcc ggccttattt gaaattgaga aaaaacaatt gctagcaagt ttagcagctg
    31321 atatggatga ttctttttat tttgcacata aagaattgga taaattgttt tttcatgatg
    31381 aacgtcttca attggaatat agtgatttac gaaatcgtat tttagctgaa actccacaaa
    31441 gttcttattc ttgtttccaa gaatttttag ccaatgatcg aatagatttc tttttcctag
    31501 gtgattttaa tgaggttgaa attcaaaatg tattagaatc atttggcttt aaaggtcgaa
    31561 aaggagatgt gaaggttcag tattgtcaac cttattctaa tatccttcag gaaggtatgg
    31621 ttcggaaaaa tgtgggacaa tccattttgg aattaggtta tcattactgt tctaaatatg
    31681 gtgatgagca acatttaccc atgattgtaa tgaatggttt acttggtgga tttgctcact
    31741 ctaagctctt tacaaatgtc cgtgaaaatg ctggattagc ttataccatt tcaagtgagc
    31801 ttgatttatt tagtggattc ttgaggatgt atgctggtat caatcgagaa aatcgtaacc
    31861 aggctcgtaa aatgatgaat aatcaactgc ttgatttaaa aaaaggttat tttacagagt
    31921 ttgagttaaa tcagaccaag gaaatgattc gttggtcgtt gttactttct caagataatc
    31981 aatcttcatt gattgaacgt gcttatcaaa atgccttatt tggaaaatct tcagcagact
    32041 ttaaaagttg gattgcaaag cttgaacaga ttgacaaaga tgctatttgt agagtagcta
    32101 ataatgtgaa actacaagcg atttacttta tggaaggaat agaatgacaa aggttgtttt
    32161 tgaagaaaaa tactatccag ctgtaaaaga aaaggtttat cgaactcgtt tggccaacgg
    32221 attgacagtt gctcttttgc ctaaaaagga atttaaagag gtttacggga gtgtaactgt
    32281 acagtttggt tcgatagata cgcttgtcac agaagttgac ggagatgtaa aacaatatcc
    32341 tggaggaatt gctcattttc ttgaacataa attatttgag agagaagatt ctagtgattt
    32401 gatgtcggct tttacgagtc taggtgcaga tagtaatgcc tttacaagct ttacaaaaac
    32461 aaactatctt ttttcagcaa cggattattt tttagaaaat ttatatttac ttgatgaatt
    32521 ggtaacatca gcacacttta ctgaagcttc cattctgaca gagcaggata ttattcagca
    32581 agaacgagaa atgtaccaag atgatccaga ttcgtgttta ttcttttcaa ctttagcgaa
    32641 tttgtatcct ggtacacctt tagcaactga tatagttgga agtgaggagt ccatttccca
    32701 aatcaatcta actaatttgc aagaaaattt tacaaagttt tacaaacctg taaacatgtc
    32761 tctgttttta gttggtaatt ttgatgtgga gcgagtacag gactattttg aaagcaaaga
    32821 actgaaagat tcagattttc aggaagtagc aagagaaaag ttgtttttac agcctgtaaa
    32881 gccaacagat agtatgagaa tggaagtatc ttctcccaaa ctagcgattg gagttagagg
    32941 taagcgagaa gtttctgaag cggattgcta tcgacatcat attttattaa aattattgtt
    33001 tgcaatgatg tttggttgga cttcggatcg ttttcaaaaa tgttatgaat caggtaaaat
    33061 tgatgcgtcc ttatctctgg aagttgaaat aacaagtcgc tttcattttg tcatgttgac
    33121 aatggatacg aaagagccag ttgctttgtc tcatcaattt aggaaggcta ttcgtaattt
    33181 tacaaaggat ttagatatta cagaggaaca tttagatatt atcaaaagag agatgtttgg
    33241 cgaatttttc agtagcatga actctcttga atttattgca acgcaatatg atgcttttga
    33301 aaatggtgag acaatttttg atttgccgaa aattttacag gaaattactt tagaggatgt
    33361 ccttgatgct ggacatcatt taatagatga tggtgacata gttgatttta caatattccc
    33421 atcgtagtaa cctattataa tagacactag aaagaaggga tgacaagtat gagaaaaaaa
    33481 acaattggag aggttttacg attagctaga atcaatcagg gattgagttt agatgaattg
    33541 cagaaaaaga cagaaatcca gttagatatg ttggaagcaa tggaagcaga cgatttcgat
    33601 caacttccaa gtccttttta cacgcgttct ttcttgaaaa aatatgcatg ggctgttgag
    33661 ttagatgacc aaattgtttt ggatgcttat gattctggga gtatgattac ttatgaggaa
    33721 gtagatgttg atgaagatga gttgacaggt cgtagacgtt caagtaagaa aaagaagaaa
    33781 aaaatatcat ttttaccttt attttatttt atcttttttg ctttatcgat tttaattttt
    33841 gtgacttatt atgtttggaa ctatattcaa actcaaccag aggagccttc tctttctaat
    33901 tacagtgtgg ttcaatcaac aagttcaact agctctgttc cccactcctc aagtagtagt
    33961 tcttctagta tagaatcagc tataagtgta tcaggcgaag gaaatcatgt agaaatcgct
    34021 tataagacaa gtaaggaaac agttaaattg caattggcag tttcagatgt tacaagttgg
    34081 gtcagtgttt cagaaagcga acttgagggc ggtgtaacct tatcgccaaa gaagaaaagt
    34141 gcagaagcaa cagttgcaac taaaagtcct gtaacaatta cgttaggtgt tgtaaaaggt
    34201 gttgatttga cagtagataa tcagactgtt gatttatcga aattaacagc tcagactgga
    34261 caaatcactg taacctttac taaaaattaa ggaaaaacga atgaaaaaag aacaaattcc
    34321 caatctctta acaataggtc gaattctctt tatacctatt tttatcttta ttttaacgat
    34381 aggaaattcg atagagagtc atatagttgc agctattatc tttgctgttg ccagtattac
    34441 cgactattta gatggatatt tagctcgtaa atggaatgtg gtcagtaatt ttggtaaatt
    34501 tgcagatcct atggcggata agttactagt tatgtcggct tttattatgt tgattgagtt
    34561 aggtatggct ccggcttgga ttgttgcagt gattatctgt cgtgagttag ctgtgacagg
    34621 tttaaggctt ttattggttg aaactggtgg aacaatttta gcagcagcaa tgcctggaaa
    34681 aattaaaact tttagtcaga tgtttgccat tattttcttg ctattacatt ggactttgct
    34741 tggtcaagtt ctactttatg tagccttatt tttcactatc tactctggct atgactattt
    34801 caagggtagt gcctatgtat ttaaagggac atttggttcg aaatgaaatc aataattgat
    34861 gtaaaaaatc tttcttttcg ctataaagaa aatcagaact actacgatgt gaaggatatt
    34921 acgtttcacg tgaaacgtgg agaatggctt tcgattgtag ggcataatgg tagtggtaaa
    34981 tcaacgacgg ttcgattaat tgatggctta ctggaagcag aatccggaga gattgtaatt
    35041 gatggccaac gtttgactga ggaaaatgtt tggaatatac gtcgtcaaat cggtatggtt
    35101 tttcaaaatc cagacaatca atttgttgga gcgactgttg aagatgatgt tgcttttggt
    35161 ttggaaaatc agggactttc tcgtcaagaa atgaaaaaga gagtggaaga agctctggct
    35221 ttagttggca tgttggactt taaaaagaga gagccagcgc gtctatcagg tggccaaaag
    35281 caacgtgtgg ccattgcagg tgttgtagcc ctaagaccag ctattttaat cttagatgaa
    35341 gcaacgagta tgttggatcc tgaggggcgt agagaactta ttgggacagt aaaaggaatt
    35401 cgaaaagact atgatatgac ggtcatttct attacccatg atttggaaga agtcgccatg
    35461 agtgatcgcg tattggtcat gaaaaaaggg gaaattgaat caactagtag tccaagggag
    35521 cttttctctc gaaatgattt agatcaaatt ggattagacg atccttttgc taatcaatta
    35581 aaaaaatctt tgagccagaa tggctatgat ttacctgaaa attatttgac agaaagtgag
    35641 ctagaggata agctatggga attgctctag aaaatgtgaa ttttacatat caagaaggta
    35701 ctcccttagc ttcagcagct ttgtcggatg tttctttgac gattgaagat ggctcttata
    35761 cagctttaat tgggcacaca ggtagtggta aatcaactat tttacaactc ttaaatggtt
    35821 tattggtgcc aagtcaaggg agtgtgaggg tttttgatac cttaatcacc tcgacttcta
    35881 aaaataaaga tattcgtcaa attagaaaac aggttggctt ggtatttcag tttgctgaaa
    35941 atcagatttt tgaagaaacg gttttgaagg acgttgcttt tggaccgcaa aattttggag
    36001 tttctgaaga agatgctgtg aagactgcgc gtgagaaact ggctctggtt ggaattgatg
    36061 aatcactttt tgatcgtagt ccgtttgagc tgtcaggggg acaaatgaga cgtgttgcca
    36121 ttgcaggcat acttgccatg gagccagcta tattagtctt agatgagcca acagctggtc
    36181 tagatcctct agggagaaaa gagttgatga ccctgttcaa aaaactccac cagtcaggga
    36241 tgaccatcgt cttggtaacg catttgatgg atgatgttgc tgaatatgcg aatcaagtct
    36301 atgtaatgga aaagggacgt ttagtaaagg ggggcaaacc aagtgatgtc tttcaagacg
    36361 ttgtttttat ggaagaagtt cagttgggag tacctaaaat tacggccttt tgtaaacgat
    36421 tggctgatag aggcgtgtca tttaaacgat taccgattaa gatagaggag ttcaaggagt
    36481 cgctaaatgg atagtatgat tttagggcgt tatatcccag gggattcgat tgttcaccga
    36541 ttggatccac gtagcaaatt gcttgctatg atgctactga ttttgattgt gttttgggct
    36601 aataacccct tgacgaatct gattcttttt atagcgacag ggatatttat tgccttgtca
    36661 ggagtatctc tttcattttt tattcagggc ttgaagtcta tgtttttctt gattgccttc
    36721 acaactattt ttcaactatt tttcatttct aatgggaatg ttttatttga gttttcgttt
    36781 gtgagaatca cggattatgc tttgcaacaa gctgggatta ttttttgtcg ctttgtattg
    36841 attattttct tttcaacttt gttaacctta acaaccatgc ctttaagttt ggcatcagct
    36901 gtcgaagctt tattagcacc tttaaagcgt gtgaaagttc cagttcatga aattggattg
    36961 atgctgtcta tgagtttgcg ttttgtccca accttgatgg atgatacgac tcggattatg
    37021 aatgcacaga aagctcgtgg agtggatttt ggagaaggaa gcatcgttca aaaagtaaag
    37081 gcgatgattc ccattttgat tcctcttttt gcgacaagtt taaaacgtgc agattccttg
    37141 gctatcgcta tggaagcgcg tggctatcag ggtggaaaag gcagaagtca ataccgacaa
    37201 ttgaaatgga ctctgaagga tacgctgacc attcttgtta ttctcgtact tggttgttgt
    37261 ttatttttct taaaatctta gtagctttca ggaattgata aaaagttact gtaacagttt
    37321 ttgatataaa ggtaggaata tgaaccgttt taaaaaatca aaatatgtca ttattgtttt
    37381 tgtcactgtt ctgcttgtgt cagctctctt agcgacgact tattcaagta caattgtgac
    37441 aaaattagga gatggaatct cattggttga tagagttgta caaaaacctt ttcagtggtt
    37501 tgattctgtc aaatcagatt tggctcattt gacacgaaca tataatgaaa atgaaagttt
    37561 gaagaaacag ctttaccaat tagaagttaa atcaaatgag gtggaaagtt taaagacaga
    37621 aaatgaacaa ctgcgccaat tgcttgatat gaagtctaaa ttgcaagcca caaagacttt
    37681 agcagcagat gttattatgc gttctccggt atcttggaag caggagttga ccttagatgc
    37741 aggtagatca aaaggtgctt ctgagaacat gttagctatt gcaaatggtg gcttgattgg
    37801 gagtgtttca aaagtagagg agaactctac tatagtcaac cttctgacaa atacggaaaa
    37861 tgctgataag atttctgtta aaattcaaca tggctctact acaatttatg gaattattat
    37921 tggctatgac aaggaaaatg acgttcttaa aattagccaa ttaaatagta atagcgatat
    37981 tagtgcggga gataaggtga ctactggtgg attaggaaac tttaacgttg ctgatattcc
    38041 tgttggtgaa gtggttgcca caacgcatag tacagactat ttgacacgag aagtaactgt
    38101 taaattgagt gcagatactc ataatgtaga tgtgatagaa ttagtgggga attcataatg
    38161 agacagttga agcgagttgg agtattttta ttgcttcctt tctttgttct aattgacgcc
    38221 catattagcc agcttctggg ctcatttttc ccccatgtac atttggctag tcattttctt
    38281 tttctatttc tcttatttga gacgatagaa gtatcagagt atctctacct agtctattgt
    38341 tttgttatag gcttggttta tgatgtttac tttttccatc taatagggat tacaactctc
    38401 ttatttatct tattgggagc cttccttcat aaattgaata gtgttatttt gttgaatcgt
    38461 tggacaagaa tgctagctat gattgtgctg acattcctgt ttgaaatggg tagttatctt
    38521 ttggctttta tggtagggtt gacagtagat agcatgtcga tttttatagt ctatagcttg
    38581 gtaccgacga tgattttaaa ttttttatgg attactgttt ttcaatttat ttttgaaaaa
    38641 tattatctat aagaacgaca tataaatgta acaaaggcgt aatatttatt aggccttttt
    38701 ttggtatact agtattgtct ttaaaagaag gagtatctac gtaatatgaa gaaaaaaatc
    38761 ttagcgtcac ttttattaag tacagtaatg gtttctcaag tagctgtttt aacaactgcg
    38821 catgcagaaa cgactgatga caaaattgct gctcaagata ataaaattag taacttaaca
    38881 gcacaacaac aagaagccca aaaacaagtt gaccaaattc aggagcaagt atcagctatt
    38941 caagctgagc agtctaactt gcaagctgaa aatgatagat tacaagcaga atctaagaaa
    39001 ctcgagggtg agattacaga actttctaaa aacattgttt ctcgtaacca atcgttggaa
    39061 aaacaagctc gtagtgctca aacaaatgga gccgtaacta gctatatcaa taccattgta
    39121 aactcaaaat caattacaga agctatttca cgtgttgctg caatgagtga aatcgtatct
    39181 gcaaacaaca aaatgttaga acaacaaaag gcagataaaa aagctatttc tgaaaaacaa
    39241 gtagcaaata atgatgctat caatactgta attgctaatc aacaaaaatt ggctgatgat
    39301 gctcaagcat tgactacgaa acaggcagaa ctaaaagctg ctgaattaag tcttgctgct
    39361 gagaaagcga cagctgaagg ggaaaaagca agtctattag agcaaaaagc agcagctgag
    39421 gcagaggctc gtgcagctgc ggtagcagaa gcagcttata aagaaaaacg agctagccaa
    39481 caacaatcag tacttgcttc agcaaacact aacttaacag ctcaagtgca agcagtatct
    39541 gaatctgcag cagcacctgt ccgtgcaaaa gttcgtccaa catacagtac aaacgcttca
    39601 agttatccaa ttggagaatg tacatgggga gtaaaaacat tggcaccttg ggctggagac
    39661 tactggggta atggagcaca gtgggctaca agtgcagcag cagcaggttt ccgtacaggt
    39721 tcaacacctc aagttggagc aattgcatgt tggaatgatg gtggatatgg tcacgtagcg
    39781 gttgttacag ctgttgaatc aacaacacgt atccaagtat cagaatcaaa ttatgcaggt
    39841 aatcgtacaa ttggaaatca ccgtggatgg ttcaatccaa caacaacttc tgaaggtttt
    39901 gttacatata tttatgcaga ttaatttaca gagggactcg aatagagccc tcttttcagg
    39961 ttttaccgtg acaatcccta ttaaaaatta tatcaaaata gcttgaaaat attggaaaag
    40021 tatggtagaa tgaaaattgt cgtgtgaacg ataatactca ttcttgatga attgtgaagc
    40081 agttgccctt gggtcgtttt gcgagttgaa gtcaagaaga ggaaaaaaac aaaaaggaga
    40141 aatactcatg gcagtaattt caatgaaaca acttcttgag gctggtgtac actttggtca
    40201 ccaaactcgt cgctggaatc ctaagatggc taagtacatc tttactgaac gtaacggaat
    40261 ccacgttatc gacttgcaac aaactgtaaa atacgctgac caagcatacg acttcatgcg
    40321 tgatgcagca gctaacgatg cagttgtatt gttcgttggt actaagaaac aagcagctga
    40381 tgcagttgct gaagaagcag tacgttcagg tcaatacttc atcaaccacc gttggttggg
    40441 tggaactctt acaaactggg gaacaatcca aaaacgtatc gctcgtttga aagaaattaa
    40501 acgtatggaa gaagatggaa ctttcgaagt tcttcctaag aaagaagttg cacttcttaa
    40561 caaacaacgt gcgcgtcttg aaaaattctt gggcggtatc gaagatatgc ctcgtatccc
    40621 agatgtgatg tacgtagttg acccacataa agagcaaatc gctgttaaag aagctaaaaa
    40681 attgggaatc ccagttgtag cgatggttga caccaatact gatccagatg atatcgatgt
    40741 aatcatccca gctaacgatg acgctatccg tgctgttaaa ttgatcacag ctaaattggc
    40801 tgacgctatt atcgaaggac gtcaaggtga ggatgcagta gcagttgaag cagaatttgc
    40861 agcttcagaa actcaagcag attcaattga agaaatcgtt gaagttgtag aaggcgacaa
    40921 cgcttaattt atacaaatag taattaccta ggagggcggg gcttagcccg gctctcctat
    40981 tttcaaaaaa tataggagaa ttaaaatggc agaaattaca gctaaacttg taaaagagtt
    41041 gcgtgaaaaa tctggtgccg gtgttatgga cgctaaaaaa gcgcttgtag aaacagacgg
    41101 tgacatcgaa aaagcgattg aattgcttcg tgaaaaaggt atggctaagg cagctaagaa
    41161 agctgaccgt gttgctgcag aaggtttgac tggtgtttat gttaacggta atgttgcagc
    41221 agttattgaa gtaaacgctg aaactgactt cgttgcaaaa aacgctcaat tcgttgaatt
    41281 ggtaaatact acagctaaag tcattgctga aggaaaacct gctaacaacg aagaagctct
    41341 tgctttgata atgccttcag gtgaaactct tgaagctgca tacgtatctg caacagcaac
    41401 tatcggagag aaaatctcat tccgtcgctt tgcattgatt gaaaaaacag acgcacaaca
    41461 ctttggagca taccaacata acggtggacg tatcggtgtt atttcagttg ttgaaggtgg
    41521 agacgaagca cttgctaaac aattgtcaat gcacatcgca gcgatgaaac caacagttct
    41581 ttcttacaaa gaattggatg agcaattcgt taaagatgag ttggcacaat tgaatcacgt
    41641 tatcgaccaa gacaacgaaa gccgtgcaat ggttaataaa ccagctcttc cacacttgaa
    41701 gtatggatca aaagctcaat taactgatga tgttattgct caagctgaag ctgacatcaa
    41761 agctgaattg gctgcagaag gtaaaccaga aaaaatctgg gacaaaatta ttccaggtaa
    41821 aatggatcgc ttcatgcttg ataacactaa agttgaccaa gcttacacac ttcttgcaca
    41881 agtttacatc atggatgaca gcaagacagt tgaagcatac cttgaatcag ttaacgcttc
    41941 ggtagttgag tttgctcgct ttgaagttgg tgaaggtatc gagaaagctg caaacgactt
    42001 cgaagctgaa gttgcagcta caatggcagc agccttgaat aactaataat agaaaggaag
    42061 caaattgctt ccttttttgt atagggctta gatttttcct gaaattgttt tttccccagc
    42121 ctcactcgat tagaataatt aaaacaaaaa gccctataat aagggctaag tgcatttagg
    42181 agactatact tcaaattcat agtaagcgcg tcataacaag gtatctatcc taattcccca
    42241 acttccagta tactagataa aaaataatta tcggaggaaa ggtattgtac tatgataatt
    42301 caactaagtg atttaggtca agttcacctt gtttgtgaca agacagatat gaggtaggga
    42361 atagactcat tagcctatgt agttaaaacc cactttgaat tggattcttt ctccggtcaa
    42421 gtctttctct tttgtggtga acgtaaagac cgctttaaag ccctttactg ggatggtcaa
    42481 ggattttggc tactatataa acgctttgag aacggaaaac tgacttggct aagtacagaa
    42541 aaggatgtca aagctctcgc acctgaacaa gtagattggc ttatgaaggg cttttctatc
    42601 actccaaaaa tatagtagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
    42661 agaaatcgat ttgattgtcc tgatcgattt gtcctgttct tatttcattt tactataaat
    42721 ccatcagaaa gttgtgattt ctattgaaat gaggactttc tttttacact catctgcttt
    42781 caaaaagcat tctagtccat ctccgattaa cgatggactt tatcacctcc ttctccagtc
    42841 cttgtatgac atcttccaaa gttcgaaagg ctttattctt aaatccacgt ttacgaatct
    42901 ctttccatac ttgttcaatg gggttcatct ctggtgtgta tggaggaata aatgcaaagc
    42961 caatattagt cggaatcttt aaggtacttg atttatgcca tatagcattg tccataacga
    43021 gtaaaagata atcatctgga taagcttgtg aaagctccta ttcctaaagc ccctttagcg
    43081 catagctttg gctcagcttc tattatcgct cacaccatcc atcagaagtt taatctgaag
    43141 gtacccaatt atcgccaaga agaagattgg gctaagatgg gtttaccaat cacacgcaag
    43201 gaaatctcta attggcatat caagacgagt caatactatt tggagcccct ctataacctc
    43261 ttgcgagaga gactattgac tcagccctta cttcatgcgg atgaaacttc ttatagggtg
    43321 ctagagagtg atagtcagct gacttactat tggacttttt tgtctgggaa agctgagaaa
    43381 caagggatta cgctttacca tcatgtccta atcgatttgt tcatatctta tttcaatcca
    43441 ttataaatag tgagaaatat ctatcctatc ttctagaatg tcttccaaac gtggaaactc
    43501 tcgtaaacaa agaggtttta gaggcttatt taccatggac taaaattgta caagaaaagt
    43561 gcaaataaga aatctccaga ttaggaacta tccgtgagtt ctctagtctg gagatttttc
    43621 aatatacttc gttattggac ggttacaatt cataaagtgc tgtagagaga taacgttcac
    43681 cgttatctgg tgctagggca aggacttttt tacctgtacc taattttttg gcaacctcga
    43741 tggctccgta gatagctgca gctgaggaaa tccctacaag gaagccttct tttccaccaa
    43801 tttcacgtcc gagtgcaaga gcgtcatctg atgttacacg aacgatacca ttataggctt
    43861 tagtatcaag tgtatcagga ataaatccag ctgagatacc ttgaattttg tgaggaccag
    43921 gtttttcacc agatagaata gcagattcat ctgcttctac tgcaaaaact tgaatgttag
    43981 aattttctga tttgagtgca tgagaaacac cagaaatcgt tccaccggta cctactccag
    44041 caacaaaggc atctaatcca tctttaccga aagcagctag tatctcagct cctgttgttc
    44101 tttcgtgtac ttctggatta gctggattgt caaattgaag aggaaggaaa ccatcacgtt
    44161 cagcagcgat ttcttgagcc ttagcaatag cacctttcat tccctcgcta ccaggagtta
    44221 ggacgagttc agcaccataa gcttggataa ttttacgtcg ttctacactc atagtttcag
    44281 gcataacgat gacgacttta taccctttag cagcacctac ccatgaaagt ccaataccag
    44341 tgtttccact tgttgcttca acaatagtag aaccaggttt cagaatacca tcttgttcag
    44401 ctttttcaat catgctaagg gcaatacggt cttttacaga tgaaccagga ttaaatgctt
    44461 caagctttat atagacgtct gcagcacctt ctggcacgat gttgttaagt ttaacaatcg
    44521 gtgtttgacc gattaattca gtaatgttgt tataaataga catatgaata cctctttgta
    44581 taagatatct ttagtataac gctatccata ccatttgtaa aatatagaaa tcctatcgaa
    44641 gcgataggat ttctatatat catagatcaa agtcattaat tttcaagtga ttgcgttcag
    44701 ctaattctag taaataggtg tgaaggaaaa cgctatcagg tttcgtttga attgcttcat
    44761 tttctagtat attttggtac gcatcttttt attttgctcg ctaaagtagt tgtgagaatg
    44821 tcaacgaaac gctgtattat tcattgttta cactaagttt acaggaactt caacctctcg
    44881 taaaccttgg tcagttaaag tgacttttcc attaaaaaac tccacaagtg cagctttaat
    44941 agtttctttt tcttctttat caacataaat catcgtatcg acttgatctg taaagtttgt
    45001 atccagctcc atgagatcat gttctttaag gaagttactg tactcttggt actgagcata
    45061 agacatttga atagcaatgc cagcctgttc ttttatttca ataataccaa tttctttgac
    45121 agctaaggcg acactgccgg cgtaagcacg aattagtcct ccagcgccta gtttaatacc
    45181 accaaagtag cgtgtcacga ccacacagac attggtgaga ttgtgatttt ctagtacccc
    45241 aagcatggga acaccagcag taccactagg ctcaccatta tcacttgtac gtttaatttc
    45301 actacgttct ccaataataa aggcagagca gttatgtgtc gctttgtagt gttctttttt
    45361 gatggcagta atgaagtcac gagcctcttc ttcgctataa acacgcttgg catggcagat
    45421 aaagcgagat ttttttattt cttcttggac ttggccgtcc tctttaattg tcctaaattc
    45481 catgatttaa ttgtactaaa aaataatcta aagtgctagt ttttacgaat agagaagtat
    45541 gaaagtaaat ttagattatc tcggtcgttt atttactgag aatgaattaa cagaagaaga
    45601 acgtcagttg gcggagaaac ttccagcaat gagaaaggag aaggggaaac ttttctgtca
    45661 acgttgtaat agtactattc tagaagaatg gtatttgccc atcggtgctt actattgtcg
    45721 agagtgcttg ctgatgaagc gagtcagaag tgatcaaact ttatactatt ttccgcagga
    45781 ggattttccg aagcaagatg ttctcaaatg gcgcggccaa ttaactcctt ttcaagagaa
    45841 ggtgtcagag ggactgcttc aagcagtaga caagcaaaag ccaaccttag ttcatgcggt
    45901 aacaggagct ggaaagacag aaatgattta tcaagtagtg gctaaagtga tcaatgcggg
    45961 tggtgcagtg tgtttggcta gtcctcgcat agatgtttgt ttggagctgt acaagcgcct
    46021 gcaacaggat ttttcttgcg ggatagcttt gctacatgga gaatcggaac cttattttcg
    46081 aacaccacta gttgttgcaa caacccatca gttattgaag ttttatcaag cttttgattt
    46141 gctgatagtg gatgaagtag atgcttttcc ttatgttgat aatcccacgc tttaccacgc
    46201 tgtcaagaat agtgtaaagg agaatggatt gagaatcttt ttaacagcga cttcgaccaa
    46261 tgagttagat aaaaaggtcc gtttaggaga actaaaaaga ctgagtttac cgagacggtt
    46321 tcatggaaat ccgttgatta ttccaaaacc aatttggtta tcggatttta atcgctactt
    46381 agacaagaat cgtttgtcac caaagttaaa gtcctatatt gagaagcaga gaaagacagc
    46441 ttatccgtta ctcatttttg cttcagaaat taagaaaggg gagcagttag aagaaatctt
    46501 acaggagcaa tttccaaatg agaaaattgg ctttgtatct tctgtaacag aggatcgatt
    46561 agagcaagta caagcttttc gagatggaga actgacaata cttatcagta cgacaatctt
    46621 ggagcgtgga gttaccttcc cttgtgtgga tgttttcgta gtagaggcca atcatcgttt
    46681 gtttaccaag tctaatttga ttcagattgg tggacgagtt ggacgaagca tggatagacc
    46741 gacaggagat ttgcttttct tccatgatgg gttaaatgct tcaatcaaga aggcgattaa
    46801 ggaaattcag atgatgaata aggaggctgg tctatgaagt gcttgttatg tgggcagact
    46861 atgaagactg ttttaacttt tagtagtctc ttacttctga ggaatgatga ctcttgtctt
    46921 tgttcagact gtgattctac ttttgaaaga attggggaag agaactgtcc aaattgtatg
    46981 aaaacagagt tgtcaacaaa gtgtcaagat tgtcaacttt ggtgtaaaga aggagttgaa
    47041 gtcagtcata gagcgatttt tacttacaat caagctatga aggatttttt cagtcggtat
    47101 aagtttgatg gagacttcct gttaagaaaa gttttcgctt catttttaag tgaggagttg
    47161 aaaaagtaca aagagtatca atttgttgta attcccctaa gtcctgatag atatgctaat
    47221 agaggattta atcaggttga gggcttggta gaggcagcag gctttgagta tctggattta
    47281 ttagagaaaa gagaagaggg agccagttct tctaaaaatc gttcagagcg cttggggaca
    47341 gaacttcctt tctttattaa aagtggagtc actattccta aaaaaatcct acttatagat
    47401 gatatctata ctacaggagc aactataaat cgtgttaaga aactgttgga agaagctggt
    47461 gctaaggatg taaaaacatt ttcccttgta agatgaggaa aaaatttgca aaaatagaat
    47521 gaaagcgtta taataaaatc ataaaaacaa aaatgtttag aaagaaggta ctcatatgat
    47581 taaatatagt atccgtggtg aaaacctaga agtaacagaa gcaattcgtg attatgtagt
    47641 ttctaaactc gaaaagatcg aaaagtactt ccaaccagaa caagagttgg atgcccgaat
    47701 taacttaaaa gtttatcgtg aaaaaacggc taaagtggaa gtaacgattc cgcttggatc
    47761 tattactctc cgcgcagaag atgtatctca agatatgtat ggttcaattg accttgtaac
    47821 tgataaaatt gaacgtcaga ttcgtaaaaa taaaacaaaa atcgagcgta aaaataaaaa
    47881 taaggtagca actggtcaat tatttacaga tgctttggtg gaagattcaa atgttgtcca
    47941 gtctaaagtt gttcgttcaa aacaaattga tttaaaacca atggatttgg aagaagcaat
    48001 tctacaaatg gatttattgg ggcatgattt ctttatctat gtggatgttg aagatcaaac
    48061 aaccaatgtg atttatcgtc gtgaggatgg cgaaattggt ttgttagagg ttaaagaatc
    48121 ttaatttcaa tatgtgtaaa ggtaggttta ctgaattgta aactaccttt ttcttataat
    48181 tgatagaatt actgattaca cttttaaaaa gtcgcttttt gaggggtatt atggtataat
    48241 gggtgccaag aggttttgaa tgaaaaaatt ttatgtaagt ccaatttttc ctattctagt
    48301 aggattgatt gcgtttggag tcttatccac tttcattatt tttgttaata ataatctgtt
    48361 gacggtttta attttgtttc tttttgtagg aggctatgtt tttttattta agaaactgag
    48421 agtgcattat acaaggagtg atgtagaaca gatacagtat gtaaaccacc aagcggaaga
    48481 aagtttgaca gctctattgg aacagatgcc tgtaggtgtt atgaaattga atttatcttc
    48541 tggagaggtt gagtggttta atccctatgc tgaattgatt ttgaccaagg aagatggtga
    48601 ttttgattta gaagctgttc aaacgattat caaggcttca gtaggaaatc cgtctactta
    48661 tgccaagctt ggtgagaagc gttatgctgt tcatatggat gcttcttccg gtgttttgta
    48721 ttttgtagat gtatccaggg aacaagccat aacagatgaa ttggtaacaa gtcgaccagt
    48781 gattgggatt gtctctgtgg ataattatga tgatttggag gatgcaactt ctgagtcaga
    48841 tattagtcaa atcaatagtt ttgtagctaa ttttatatca gagttttcag aaaaatacat
    48901 gatgttttct cgtcgggtaa gtatggatcg attttatcta tttactgact acacggtgct
    48961 tgagggcttg atgaatgata aattttctgt tattgatgct ttcagagaag agtcgaaaca
    49021 gagacagttg cccttgacct taagtatggg attttcttat ggcgatggaa atcatgatga
    49081 gatagggaaa gttgctttgc tcaatttgaa cttggctgaa gtacgtggtg gcgaccaggt
    49141 ggttgttaag gaaaacgacg aaacgaaaaa tccagtttat tttggtggtg ggtctgctgc
    49201 ttcaatcaag cgtacacgga ctcgtacgcg cgctatgatg acagctattt cagataagat
    49261 tcggagtgta gatcaggttt ttgtagtcgg tcacaaaaat ttagacatgg atgctttggg
    49321 ctctgctgta ggtatgcagt tgttcgccag caatgtgatt gaaaatagct atgctcttta
    49381 tgatgaagaa caaatgtctc cagatattga acgagctgtt tcattcatag aaaaagaagg
    49441 agttacgaag ttgttgtctg ttaaggatgc aatggggatg gtgaccaatc gttctttgtt
    49501 gattcttgta gaccattcaa agacagcctt aacattatca aaagaatttt atgatttatt
    49561 tacccaaacc attgttattg accaccatag aagggatcag gattttccag ataatgcggt
    49621 cattacttat atcgaaagtg gtgcaagtag tgccagtgag ttggtaacgg aattgattca
    49681 gttccagaat tctaagaaaa atcgtttgag tcgtatgcaa gcaagtgttt tgatggctgg
    49741 tatgatgttg gatactaaaa atttcacctc gcgagtaact agtcggacat ttgatgttgc
    49801 tagctatctc agaacgcgcg gaagtgatag tattgctatc caggaaatcg ctgcgacaga
    49861 ttttgaagaa tatcgtgagg tcaatgaact tattttacag gggcgtaaat taggttcaga
    49921 tgtactaata gcagaggcta aggacacgaa atgctatgat acagttgtta ttagtaaggc
    49981 agcagatgcc atgttagcca tgtcaggtat tgaagcgagt tttgttcttg cgaagaatac
    50041 acaaggattt atctctatct cagctcgaag tcgtagtaaa ctgaatgtac aacggattat
    50101 ggaagagtta ggcggtggag gccactttaa tttggcagca gctcaaatta aagatgtaac
    50161 cttgtcagaa gcaggtgaaa aactgacaga aattgtatta aatgaaataa aggaaaagga
    50221 gaaagaagaa tgaaagtaat ctttttagca gatgttaaag gaaaaggtaa aaaaggcgaa
    50281 attaaggaag taccaacagg gtatgcgcaa aactttctta tcaaaaagaa tctagccaaa
    50341 gaagcgactg ctcaagctgt aggtgaactt cgtggtaaac aaaaatcgga agaaaaagct
    50401 cacgctgaga tgattgcaga aggaaaagca attaaagcac aacttgaagc agaagaaact
    50461 gttgtagaat ttgttgaaaa agttggtcca gatggtcgta cctttggttc tattaccaat
    50521 aagaagattg cagaagaatt gcaaaagcaa tttggaatta agattgataa acgtcatatt
    50581 caagtacaag ctccgattcg agcggttggt ttgattgatg tgccagtgaa aatctatcaa
    50641 gatatcacaa gtgtaatcaa tcttcgtgtg aaagaaggat aagtttacac cttcttgaca
    50701 agattgtaaa aggaagggaa gtctgatggc agaagtagaa gagttacgag tacaacctca
    50761 agatatctta gctgagcaat ccgttttagg ggctatcttt attgatgaga gtaaacttgt
    50821 ttttgtgcga gaatacattg agtctcggga cttttttaag tatgcccatc gtttgatttt
    50881 ccaagccatg gtcgatttat ccgatcgtgg tgatgccata gatgcaacaa cggttcgtac
    50941 tatccttgat aatcaaggtg atttacagaa tattggtggc ttgtcttact tggttgagat
    51001 tgttaattct gtgccaactt ctgctaatgc ggagtattat gctaagattg ttgcagaaaa
    51061 agcaatgcta cgtcgtttaa ttgccaagtt gacagagtct gtcaaccaag cttacgaagc
    51121 gtcacaacca gctgatgaaa ttattgctca ggcagaaaaa gggctgattg atgtcagtga
    51181 aaatgcaaat cgaagcgggt ttaagaacat tcgagatgtg ttgaatctca actttggaaa
    51241 tctggaagct cgctcgcaac aaacgaccga tattacaggt attgcgacag gttatcgtga
    51301 tttggatcat atgacaacag gacttcatga ggaggagttg attatcttag cagctcgtcc
    51361 agcagttggt aagacagcat ttgccttgaa tatcgctcag aacattggga ctaagttgga
    51421 caaaacggtt gctatttttt cactcgaaat gggtgcggaa agcttggtag atcgtatgtt
    51481 agctgcagaa ggcttggtgg agtcacattc tatccgtaca gggcaattga cagatgagga
    51541 gtggcaaaaa tatactattg ctcagggtaa tctagctaac gccagtatct atatcgatga
    51601 tacgccaggt attcggatta cagagattcg ttctcgttct cgtaaattgg ctcaagaaac
    51661 tggaaatctt ggtttgattt tgatagacta tttacaactt atcacgggaa ctggtcgaga
    51721 aaatcgtcaa caagaagttt ctgaaatttc tcgtcagttg aaaatactag ccaaggaatt
    51781 gaaggttcca gtaatcgctc tgagtcagct ttctcgtggt gtagaacaac gtcaggacaa
    51841 gagaccggtc ttgtctgata ttcgtgaatc tgggtctatt gagcaggacg ctgatatcgt
    51901 agcttttctc tatcgcgatg actactatga acgtggtggt gaagaagagg agggtatccc
    51961 aaataataag gtggaagtta ttatcgagaa aaaccgtagt ggagctcgtg gaacagtgga
    52021 attgattttc caaaaagaat acaataaatt ttcaagtatc tcaaagaggg aggcataaga
    52081 tgtcagatgc atttacagat gtagccaaga tgaaaaaaat caaagaagaa atcaaggcac
    52141 atgagggaca agtcgtagaa atgactttgg agaatggtcg taagcgccaa aaaaatagat
    52201 tgggtaagct aattgaagtt tatccatccc tatttattgt ggagtttggg gatgtggaag
    52261 gagataaaca agttaatgtt tacgttgaat cctttactta ctcagatatt cttacagaaa
    52321 agaatttgat tcattatctt gactaaagtg agaaattttc tcactttttc ttttttctcc
    52381 gaataattta ggtgaaggca atcatcgctt tatattattt ttcaaggagg aagaatgaaa
    52441 attttaccgt ttatagcaag aggaacaagt tattacttga agatgtcagt taaaaagctt
    52501 gttccttttt tagtagtagg attgatgcta gcagctggtg atagtgtcta tgcctattcc
    52561 ggaggaaatg gatcgattgc gcgtggggat gattatcctg cttattataa aaatgggagc
    52621 caggagattg atcagtggcg catgtattct cgtcagtgta cttcttttgt agcctttcgt
    52681 ttgagtaatg tcaatggttt tgaaattccg gcagcttatg gaaatgcgaa tgaatgggga
    52741 catcgtgctc gtcgggaagg ttatcgtgta gataatacac cgacgattgg ttccattact
    52801 tggtctactg caggaactta tggtcatgtt gcctgggtgt caaatgtaat gggagatcag
    52861 attgagattg aggaatataa ctatggttat acagaatcct ataataaacg aattataaaa
    52921 gcaaacacga tgacaggatt tattcatttt aaagatttgg atggtggcag tgttgggaat
    52981 agtcaatcct caacttcaac aggcggaact cattatttta agaccaagtc tgctattaaa
    53041 actgaacccc tagttagtgc aactgtgatt gattactatt atcctggaga gaaggttcat
    53101 tatgatcaaa ttctcgaaaa agacggctac aagtggttga gttatacggc ttataacgga
    53161 agtcgtcgct atatacagct agagggagtg acttcttcac aaaattatca gaatcaatca
    53221 ggaaatatct ctagctatgg atccaataat agttcaactg tcggttggaa gaaaataaat
    53281 ggtagttggt atcatttcaa atcaaatggt tctaaatcaa caggatggct gaaagacggt
    53341 tctagctggt attatttgaa attatctggt gaaatgcaga caggatggtt aaaggaaaat
    53401 ggtttgtggt attatctggg tagttcaggg gcaatgaaaa caggctggta ccaggtctct
    53461 ggtaagtggt attattctta ctcttcaggc gccttagctg ttaatacgac ggtggatggc
    53521 tacagagtaa acagtgatgg agaacgagta tagaaaattg gagtaggaga aatttcctgc
    53581 tcttttctgt aagcagtttc cttgacattt ttcttatttt gcgctatcat atatacatat
    53641 aatatatggg agtctgtgta cagtctgaga ggaagtgtta aacttcgacc gcacctgatc
    53701 tgggtaatgc cagcggaggg aacgatactt agtctaattt tgcacctttt ccatgtatgg
    53761 taaaggtttt tctttttttt aaaaggaaaa cgagaagagg aggttcttat gaaagcaagc
    53821 attgccttgc aagttttacc cctagcacag gggattgatc ggatagctgt tattgatcag
    53881 gtcattgctt atctgcaaac tcaagaagtg acgatggtag tgacaccatt tgaaacggtc
    53941 ttggaagggg agtttgatga gcttatgcgc attctaaaag aagcgctgga agtggcaggg
    54001 caggaggcag acaatgtctt tgccaatgtc aaaataaatg taggagagat tttaagtatt
    54061 gatgagaaac ttgaaaagta tactgagacg acacattagt ctattgggct ttctcggagt
    54121 attgtcaatc tggcagttag caggttttct taaacttctc cccaagttta tcctgccgac
    54181 acctcttgaa attctccagc cctttgttcg tgacagagaa tttctctggc accatagctg
    54241 ggcgaccttg agagtggctt tactggggct gattttggga gttttgattg cctgtcttat
    54301 ggctgtgctc atggatagtt tgacttggct caatgacctg atttacccta tgatggtggt
    54361 cattcagacc attccgacca ttgccatagc tcctatcctg gttttgtggc tgggttatgg
    54421 gattttgccc aagattgtct tgattatctt aacaacaacc tttcccatca tcgttagtat
    54481 tttggacggt tttaggcatt gcgacaagga tatgctgact ttgtttagtc tgatgcgagc
    54541 aaacccttgg caaatcctgt ggcattttaa aatcccggtt agcctgcctt acttttatgc
    54601 aggtctgagg gtcagtgtct cctacgcctt tatcacaact gtggtatctg agtggttggg
    54661 aggttttgaa ggtcttggtg tttatatgat tcagtctaaa aaactgtttc agtatgatac
    54721 catgtttgcc attattattc tggtgtcgat tatcagtctt ttgggtatga agctggtcga
    54781 tatcagtgaa aaatatgtga ttaaatggaa acgtacttaa aatagagcgt ttttgaaaaa
    54841 gaaaagagga aatcaaaatg aagaaaacat ggaaagtgtt tttaacgctt gtaacagctc
    54901 ttgtagctgt tgtgcttgtg gcctgtggtc aaggaactgc ttctaaagac aacaaagagg
    54961 cagaacttaa gaaggttgac tttatcctag actggacacc aaataccaac cacacagggc
    55021 tttatgttgc caaggaaaaa ggttatttca aagaagctgg agtggatgtt gatttgaaat
    55081 tgccaccaga agaaagttct tctgacttgg ttatcaacgg aaaggcacca tttgcagtgt
    55141 atttccaaga ctacatggct aagaaattgg aaaaaggagc aggaatcact gccgttgcag
    55201 ctattgttga acacaataca tcaggaatca tctctcgtaa atctgataat gtaagcagtc
    55261 caaaagactt ggttggtaag aaatatggga catggaatga cccaactgaa cttgctatgt
    55321 tgaaaacctt ggtagaatct caaggtggag actttgagaa ggttgaaaaa gtaccaaata
    55381 acgactcaaa ctcaatcaca ccgattgcca atggcgtctt tgatactgct tggatttact
    55441 acggttggga tggtatcctt gctaaatctc aaggtgtaga tgctaacttc atgtacttga
    55501 aagactatgt caaggagttt gactactatt caccagttat catcgcaaac aacgactatc
    55561 tgaaagataa caaagaagaa gctcgcaaag tcatccaagc catcaaaaaa ggctaccaat
    55621 atgccatgga acatccagaa gaagctgcag atattctcat caagaatgca cctgaactca
    55681 aggaaaaacg tgactttgtc atcgaatctc aaaaatactt gtcaaaagaa tacgcaagcg
    55741 acaaggaaaa atggggtcaa tttgacgcag ctcgctggaa tgctttctac aaatgggata
    55801 aagaaaatgg tatccttaaa gaagacttga cagacaaagg cttcaccaac gaatttgtga
    55861 aataatgaca gaaattagac tagagcacgt cagttatgcc tatggtcagg agaggatttt
    55921 agaggatatc aacctacagg tgacttcagg cgaagtggtt tccatcctag gcccaagtgg
    55981 tgttggaaag accaccctct ttaatctaat cgctgggatt ttagaagttc agtcagggag
    56041 aattgtcctt gatggtgaag aaaatcccaa ggggcgcgtg agttatatgt tgcaaaagga
    56101 tctgctcttg gagcacaaga cggtgcttgg aaatatcatt ctgcccctct tgattcaaaa
    56161 ggtggataag gcagaagcta tttcccgagc ggataaaatt cttgcgacct tccagctgac
    56221 agctgtaaga gacaagtatc ctcatgaact tagcggtggg atgcgccagc gtgtagcctt
    56281 actccggacc tacctttttg ggcacaagct ctttctctta gatgaggcct ttagcgcctt
    56341 ggatgagatg acaaagatgg aactccacgc ttggtatctt gagattcaca agcagttgca
    56401 gctaacaacc ctgatcatca cgcatagtat tgaggaggcc ctcaatctca gcgaccgcat
    56461 ctatatcttg aaaaatcgcc ctgggcagat tgtttcagaa attaaactag attggtctga
    56521 agatgaggac aaggaagtcc aaaagattgc ctacaaacgt caaatcttgg cagaattagg
    56581 cttagataag tagaaaaata gggagttggt gaagattatc ctttaccagc gccctttttc
    56641 ttttaaaaat gagaaaattt cggtataata gtcaaacaag gtcaaggttt aaagagagag
    56701 gtgggtttgt tatgagattt aaaaatacat cggatcatat tgaggcctac atcaaggcga
    56761 ttttagatca atctggtatc gtggagttgc aacggagtca gttggcagat acctttcagg
    56821 ttgttcctag tcagattaac tacgtgatca agacacgctt tacggaaagt agaggctact
    56881 tggttgaaag taagcgtggt ggcggaggct acattcgtat aggacggatt gagttttcta
    56941 gtcatcatga aatgctccgg gagctgcttt actcgattgg tgagcgagtc agtcaagaaa
    57001 tttatgagga tattctccag cttttggttg agcaggaatt gatgaccaag caggagatga
    57061 atttgctaga atcagtagct ttggatcgcg ttttaggaga agaagctcca gttgttcgag
    57121 caaacatgct acgtcagatc atacaagagg tagatagaaa agggaagtaa gatgaactat
    57181 tcaaaagcat tgaatgaatg tatcgaaagt gcctacatgg ttgctggaca ttttggagct
    57241 cgttatctag agtcttggca cttgttgatt gccatgtcta atcacagtta tagtgtagca
    57301 ggggcaactt taaatgatta tccgtatgag atggaccgtt tagaagaggt ggctttggaa
    57361 ctgactgaaa cggactatag ccaggatgaa acctttacgg aattgccgtt ctcccgtcgt
    57421 ttgcaggttc tttttgacga agcagagtat gtagcgtcag tggtccatgc taaggtgcta
    57481 gggacagagc acgtcctcta tgcgattttg catgatggca atgccttggc gactcgtatc
    57541 ttggagaggg ctggattttc ttatgaagac aagaaagatc aggtcaagat tgctgctctt
    57601 cgtcgaaatt tagaagaacg ggcaggctgg actcgtgaag atctcaaggc tttacgccaa
    57661 cgccatcgta cagtagctga caagcaaaat tctatggcca atatgatggg catgccgcag
    57721 actcctagtg gtggtctcga ggactatacg catgatttga cagagcaagc gcgttctggc
    57781 aagttagaac cagtcatcgg tcgggacaag gaaatctcac gtatgattca aatcttgagc
    57841 cggaagacta agaacaaccc tgtcttggtt ggggatgctg gtgtcgggaa aacagctctg
    57901 gcgcttggtc ttgcccagcg tattgctagt ggtgacgtgc ctgcggaaat ggctaagatg
    57961 cgcgtgttag aacttgattt gatgaatgtc gttgcaggga cacgcttccg tggtgacttt
    58021 gaagaacgca tgaataatat catcaaggat attgaagaag atggccaagt catcctcttt
    58081 atcgatgaac tccacaccat catgggttct ggtagcggaa ttgattcgac tctggatgcg
    58141 gccaatatct tgaaaccagc cttggcgcgt ggaactttga gaacggttgg tgccaccact
    58201 caggaagaat atcaaaaaca tatcgaaaaa gatgcggcac tttctcgtcg tttcgctaaa
    58261 gtgacgattg aagaaccaag tgtggcagat agtatgacta ttttacaagg tttgaaggcg
    58321 acttatgaga aacatcaccg tgtacaaatc acagatgaag cggttgaaac agcggttaag
    58381 atggctcatc gttatttaac cagtcgtcac ttgccagact ctgctatcga tctcttggat
    58441 gaggcggcag caacagtgca aaataaatca aagcatgtaa aagcagacga ttctgacttg
    58501 agtccagctg acaaggcctt gatggatggc aagtggaaac aggcagccca gctaatcgca
    58561 aaagaagagg aagtgcctgt ctataaagac ttggtgacag agtctgatat tttgaccacc
    58621 ttgagtcgct tgtcaggtat ccccgttcaa aaactgactc agactgatgc caagaaatac
    58681 ttaaacttgg aagctgaact gcacaaacgt gtcatcggtc aagaccaagc tgtttcaagt
    58741 attagtcgtg ccattcgccg caatcagtca ggaattcgca gtcacaagcg tccgatcggt
    58801 tcctttatgt tcctaggacc cacaggtgtc ggtaagaccg agttggccaa ggctttggca
    58861 gaagttctct ttgatgacga atcagccctt atccgctttg atatgagtga gtatatggag
    58921 aaattcgcag ccagccgtct aaatggagct cctccaggct atgtgggtta cgaagaaggt
    58981 ggggagttga cagagaaggt tcgcaataaa ccctattccg ttctcctctt tgatgaggta
    59041 gagaaggccc atccagatat ctttaatgtt ctcttgcagg ttctggatga cggtgtcttg
    59101 acagatagca agggacgcaa ggtcgatttt tcaaatacca ttatcattat gacatcgaac
    59161 ttaggtgcga ctgcccttcg tgatgataag actgttggtt ttggggctaa ggatattcgt
    59221 tttgaccagg aaaatatgga aaaacgcatg tttgaagaac tgaaaaaagc ttatagaccg
    59281 gaattcatca accgtattga tgagaaggtg gtcttccata gcctatctag tgaccatatg
    59341 caggaagtgg tgaagattat ggtcaagcct ttagtggcaa gtttggctga aaaaggcatt
    59401 gacttgaaat tacaagcttc agctctgaaa ttgttagcaa atcaaggata tgacccagag
    59461 atgggagctc gcccacttcg cagaaccctg caaacagaag tggaggacaa gttggcagaa
    59521 cttcttctca agggagattt agtggcaggc agcacactta agattggtgt caaagcaggc
    59581 cagttaaaat ttgatattgc ataaaagaat aaaagtacca gcatctgacc ataagtcaca
    59641 gtggagtgaa actcaatgaa aatcaaagag caaactaggc agctagccgc aggttgctca
    59701 aaacactgtt ttgaggttgc agatagagct gacgtggttt gaagagattt ttgaagagta
    59761 taagctgcaa gatgaatgat tttcttgtat tgacgttgtt gttgacaaaa agtagcggat
    59821 aaatgaaatc cattccatta tcatagatga taggctggta ggaaattttc aaatagcata
    59881 cagaaaatag atgtatggag ttctggtagt agaaagggag agagatgaac attttagttg
    59941 cagatgacga ggaaatgatt agagaaggaa ttgcagcatt tctgacagaa gagggttatc
    60001 atgtcattat ggctaaggat ggacaagagg tcttggaaaa atttcaagat ctccctatcc
    60061 atctcatggt actggattta atgatgccta ggaagagtgg ttttgaagtg ttaaaagaaa
    60121 tcaatcaaaa gcacgatatt cctgtcatcg tcttgagtgc tctgggagat gaaactactc
    60181 agtcacaggt atttgatctc tatgctgatg atcatgtgac aaaacctttt tctttggtac
    60241 tgcttgtcaa gcgtattaag gcgcttatca gacgttacta cgtcatagag gatctttggc
    60301 gatatcagga tgtaacagtg gattttacct cttacaaagc acattataaa aatgaagaaa
    60361 ttgatctcaa accaaaggaa ttactggtac taaagtgttt gattcagcat aaaaatcaag
    60421 ttttaagtag agagcagata ttggaagaaa tttcaaaaga tgtagctgat ttaccttgtg
    60481 atagggtcgt tgatgtctat attcgtactc ttcgcaaaaa attagcttta gattgtatcg
    60541 tgactgtgaa aaatgttggg tataagatta gcttatgata aaaaatccta aattattaac
    60601 caagtctttt ttaagaagtt ttgcaattct aggtggtgtt ggtctagtca ttcatatagc
    60661 tatttatttg acctttcctt tttattatat tcaactggag ggggaaaagt ttaatgagag
    60721 cgcaagagtg tttacggagt atttaaagac taagacatct gatgaaattc caagcttact
    60781 ccagtcttat tcaaagtcct tgaccatatc tgctcacctt aaaagagata ttgtagataa
    60841 gcggctccct cttgtgcatg acttggatat taaagatgga aagctatcaa attatatcgt
    60901 gatgttagat atgtctgtta gtacagcaga tggtaaacag gtaaccgtgc aatttgttca
    60961 cggggtggat gtctacaaag aagcaaagaa tattttgctt ttgtatctcc catatacatt
    61021 tttggttaca attgcttttt cctttgtttt ttcttatttt tatactaaac gcttgctcaa
    61081 tcctcttttt tacatttcag aagtgactag taaaatgcaa gatttggatg acaatattcg
    61141 ttttgatgaa agtaggaaag atgaagttgg tgaagttggt gaagttggaa aacagattaa
    61201 tggtatgtat gagcacttgt tgaaggttat tcatgagttg gaaagtcgta atgagcaaat
    61261 tgtaaaattg caaaatcaaa aggtttcctt tgtccgtgga gcatcacatg agttgaaaac
    61321 ccctttagcc agtcttagaa ttatcctaga gaatatgcag cataatattg gagattacaa
    61381 agatcatcca aaatatattg caaagagtat aaataagatt gaccagatga gccgcttatt
    61441 ggaagaagta ctggagtctt ctaaattcca agagtggaca gagtgtcgtg agaccttgac
    61501 tgttaagcca gttttagtag atattttatc acgttatcaa gaattagctc attcaatagg
    61561 tgttacaatt gaaaatcaat tgacagatgc taccagggtc gtcatgagtc ttagggcatt
    61621 ggataaggtt ttgacaaacc tgattagtaa tgcaattaaa tattcagata aaaatgggcg
    61681 cgtaatcata tccgagcaag atggctatct ctctatcaaa aatacatgtg cgcctctaag
    61741 tgatcaagaa ctagaacatt tatttgatat attctatcat tctcaaatcg tgacagataa
    61801 ggatgaaagt tctggtttgg gtctttacat tgtgaataat attttagaaa gctatcaaat
    61861 ggactatagt tttctccctt atgaacacgg tatggaattt aagattagct tgtagacaga
    61921 ttagtttttt attaaagttc atatagggtt aacataagtg tgttattctt tgtgtagata
    61981 aaagaaagga tactaatatg gtattagcga ttattttagt aacattcttt attcgattga
    62041 tttttttaaa gcgttcgata gagaatgaga aacgaatcct tagcaatggc gggaaagaat
    62101 ttggagttga gaatacaaaa cgattaacta tggctcatat tgttttttat ctctcttgct
    62161 tggttgaggc aatggtgcac aagacaattt ttgatggcat gggcatggtt ggtttggtct
    62221 tgcttatttt ttctatgctg atgttgatgt tggtgattca cttgttggga gatatttgga
    62281 cagtgaagct tatgcttgtc aataatcaca aatatgtaga tcatatcttg tttaggacag
    62341 taaaacaccc taattacttt ttaaatattt tacctgagtt gattggcttg accttgttga
    62401 gtcatgctta tgtgactttt gttttagttt ttccagttta tgcagttatt ttgtatcgac
    62461 gaatagctga agaggaaaag ctattacatg aagttataat cccaaatgga agcataaaga
    62521 gataaataca aaattcgatt tatatacagt tcatattgaa gtgatatagt aaggttaaag
    62581 aaaaaatata gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa gtacattatt
    62641 caattcgtaa atttagtatt ggagtagcta gtgtagtagt tgctagcttg ttcttaggag
    62701 gagtagtcca tgcagaaggg gttagaagtg agaataaccc cacggttaca tctagtgggc
    62761 aagatatatc gaagaagtat gctgatgaag tcaagtcaca tctagaaaaa atattgagtg
    62821 agatccaaac aaatttagat agaagtaaac atatcaaaac tgtaaatcta attaacaaat
    62881 tgcaagacat taagagaacg tatttgtatg aattaaatgt tttagaagat aagtcgaaag
    62941 ctgagttgcc gtcaaaaata aaagcagagt tagacgcagc ttttgagcag tttaaaaaag
    63001 atacattacc aacagaacca ggaaaaaagg tagcagaagc taagaagaag gttgaagaag
    63061 ctgagaaaaa agccaaggct caaaaagaag aagattaccg taactaccca accattactt
    63121 acaaaacgct tgaacttgaa attgctgagt ccgatgtgaa agttaaagaa gcggagcttg
    63181 aactagtaaa aaaggaagct gacgaatctc gaaacgaggg cacaattaac caagcaaaag
    63241 cgaaagttga gagtgaacaa gctgaggcta caaggttaaa aaaaatcaag acagatcgtg
    63301 aaaaagcaga agaagaagct aaacgaagag cagatgctaa agagcaagat gaatcaaaga
    63361 ggcgaaagag tcgggtaaaa cgaggagatc ttggagagcc agcaacacct gataaaaaag
    63421 aaaatgatgc gaagtcttca gattctagcg taggtgaaga aactcttcca agcccatccc
    63481 tgaaaccagg aaaaaaggta gcagaagctg agaagaaggt tgaagaagct gagaaaaaag
    63541 ccaaggatca aaaagaagaa gatcaccgta actacccaac cattacttac aaaacgcttg
    63601 aacttgaaat tgctgagtcc gatgtggaag ttaaaaaagc ggagcttgaa ctagtaaaag
    63661 aggaagctaa gggatctcga aacgaggaaa aagttaagca agcaaaagcg gaagttgaga
    63721 gtaaaaaagc tgaggctaca aggttagaaa aaatcaagac agatcgtaaa aaagcagaag
    63781 aagaagctaa acgaaaagca gcagaagaag ataaagttaa agaaaaacca gctgaacaac
    63841 cacaaccagc gccggctcct caaccagaaa aaccagctcc agctccaaaa ccagagaatc
    63901 cagctgaaca accaaaagca gaaaaaccag ctgatcaaca agctgaagaa gactatgctc
    63961 gtagatcaga agaagaatat aatcgcttga ctcaacagca accgccaaaa actgaaaaac
    64021 cagcacaacc atctactcca aaaacaggct ggaaacaaga aaacggtatg tggtacttct
    64081 acaatactga tggttcaatg gcgacaggat ggctccaata caatggttca tggtactacc
    64141 tcaacgctaa tggtgatatg gcgacaggat ggttccaata caatggttca tggtactacc
    64201 tcaacgctaa tggtgatatg gcgacaggat ggctccaata caatggttca tggtactacc
    64261 taaacagcaa tggtgctatg gtaacaggat ggctccaata caatggttca tggtactacc
    64321 tcaacgctaa cggttcaatg gcaacagatt gggtgaaaga tggagatacc tggtactatc
    64381 ttgaagcatc aggtgctatg aaagcaagcc aatggttcaa agtatcagat aaatggtact
    64441 atgtcaatgg ctcaggtgcc cttgcagtca acacaactgt agatagctat agagtcaatg
    64501 ccaatggtga atgggtaaac taaacctaat ataactcgtt aatgctggct tcctgtaaga
    64561 actctttaaa gtattcccta caaataccat atcctttcag tagataatat acccttgtag
    64621 gaagtttaga ttaaaaaata actctgtaat ctctagccgg atttatagcg ctagagacta
    64681 cggagttttt tggctctttg tcaactgtag tgggttgaaa aaaagctaag ctcgagaaag
    64741 gacaaatt
//
LOCUS       DAVKBK010000007        58667 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVKBK010000007 DAVKBK010000000
VERSION     DAVKBK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.007"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            226..897
                     /locus_tag="VWX69_000448"
     CDS             226..897
                     /locus_tag="VWX69_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9191848.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(949..1146)
                     /locus_tag="VWX69_000449"
     CDS             complement(949..1146)
                     /locus_tag="VWX69_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191849.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            1139..2047
                     /locus_tag="VWX69_000450"
     CDS             1139..2047
                     /locus_tag="VWX69_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9191850.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            2044..2505
                     /locus_tag="VWX69_000451"
     CDS             2044..2505
                     /locus_tag="VWX69_000451"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU9191851.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            2495..3382
                     /locus_tag="VWX69_000452"
     CDS             2495..3382
                     /locus_tag="VWX69_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9191852.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            3385..5268
                     /gene="cbpE"
                     /locus_tag="VWX69_000453"
                     /gene_synonym="pce"
     CDS             3385..5268
                     /gene="cbpE"
                     /locus_tag="VWX69_000453"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU9191853.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVARHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            5348..6478
                     /locus_tag="VWX69_000454"
     CDS             5348..6478
                     /locus_tag="VWX69_000454"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU9191854.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            6488..7750
                     /locus_tag="VWX69_000455"
     CDS             6488..7750
                     /locus_tag="VWX69_000455"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU9191855.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            7754..8551
                     /gene="proC"
                     /locus_tag="VWX69_000456"
     CDS             7754..8551
                     /gene="proC"
                     /locus_tag="VWX69_000456"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU9191856.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            8667..9305
                     /locus_tag="VWX69_000457"
     CDS             8667..9305
                     /locus_tag="VWX69_000457"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU9191857.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTNAVLFDGMGLAK"
     gene            9302..10192
                     /locus_tag="VWX69_000458"
     CDS             9302..10192
                     /locus_tag="VWX69_000458"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU9191858.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            10232..10549
                     /gene="yabA"
                     /locus_tag="VWX69_000459"
     CDS             10232..10549
                     /gene="yabA"
                     /locus_tag="VWX69_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU9191859.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            10552..11421
                     /gene="rsmI"
                     /locus_tag="VWX69_000460"
     CDS             10552..11421
                     /gene="rsmI"
                     /locus_tag="VWX69_000460"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU9191860.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            11648..12166
                     /locus_tag="VWX69_000461"
     CDS             11648..12166
                     /locus_tag="VWX69_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU9191861.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            12275..12923
                     /locus_tag="VWX69_000462"
                     /pseudo
     CDS             12275..12923
                     /locus_tag="VWX69_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(12912..13715)
                     /locus_tag="VWX69_000463"
                     /pseudo
     CDS             complement(12912..13715)
                     /locus_tag="VWX69_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            13710..13964
                     /locus_tag="VWX69_000464"
     CDS             13710..13964
                     /locus_tag="VWX69_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU9191862.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            14210..15544
                     /gene="trmFO"
                     /locus_tag="VWX69_000465"
     CDS             14210..15544
                     /gene="trmFO"
                     /locus_tag="VWX69_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU9191863.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            15628..16365
                     /locus_tag="VWX69_000466"
     CDS             15628..16365
                     /locus_tag="VWX69_000466"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU9191864.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            16374..16931
                     /gene="frr"
                     /locus_tag="VWX69_000467"
     CDS             16374..16931
                     /gene="frr"
                     /locus_tag="VWX69_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU9191865.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            16991..17845
                     /gene="cvfB"
                     /locus_tag="VWX69_000468"
     CDS             16991..17845
                     /gene="cvfB"
                     /locus_tag="VWX69_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU9191866.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            17854..18069
                     /locus_tag="VWX69_000469"
     CDS             17854..18069
                     /locus_tag="VWX69_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU9191867.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            18155..19123
                     /locus_tag="VWX69_000470"
     CDS             18155..19123
                     /locus_tag="VWX69_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU9191868.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(19101..19280)
                     /locus_tag="VWX69_000471"
     CDS             complement(19101..19280)
                     /locus_tag="VWX69_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191869.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            19316..19816
                     /locus_tag="VWX69_000472"
     CDS             19316..19816
                     /locus_tag="VWX69_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9191870.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            19819..20079
                     /locus_tag="VWX69_000473"
                     /pseudo
     CDS             19819..20079
                     /locus_tag="VWX69_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(20446..20772)
                     /locus_tag="VWX69_000474"
     CDS             complement(20446..20772)
                     /locus_tag="VWX69_000474"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191871.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(20718..21131)
                     /locus_tag="VWX69_000475"
     CDS             complement(20718..21131)
                     /locus_tag="VWX69_000475"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU9191872.1"
                     /translation="MGAHFLTKQAGGSGVLPSGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(21132..21557)
                     /locus_tag="VWX69_000476"
     CDS             complement(21132..21557)
                     /locus_tag="VWX69_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU9191873.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            21734..22303
                     /locus_tag="VWX69_000477"
     CDS             21734..22303
                     /locus_tag="VWX69_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9191874.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNSASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            22371..23021
                     /locus_tag="VWX69_000478"
     CDS             22371..23021
                     /locus_tag="VWX69_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU9191875.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            23005..25245
                     /locus_tag="VWX69_000479"
     CDS             23005..25245
                     /locus_tag="VWX69_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU9191876.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPLSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            25387..25611
                     /locus_tag="VWX69_000480"
     CDS             25387..25611
                     /locus_tag="VWX69_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191877.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYDSYSEYPVGSGWNYGRYEIINYYSGGY"
     gene            25644..26231
                     /locus_tag="VWX69_000481"
     CDS             25644..26231
                     /locus_tag="VWX69_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191878.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            26235..27416
                     /locus_tag="VWX69_000482"
     CDS             26235..27416
                     /locus_tag="VWX69_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191879.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKMQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    27576..27707
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            27723..28253
                     /gene="infC"
                     /locus_tag="VWX69_000483"
     CDS             27723..28253
                     /gene="infC"
                     /locus_tag="VWX69_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU9191880.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            28286..28486
                     /gene="rpmI"
                     /locus_tag="VWX69_000484"
     CDS             28286..28486
                     /gene="rpmI"
                     /locus_tag="VWX69_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU9191881.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            28538..28897
                     /gene="rplT"
                     /locus_tag="VWX69_000485"
     CDS             28538..28897
                     /gene="rplT"
                     /locus_tag="VWX69_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU9191882.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            28955..29335
                     /locus_tag="VWX69_000486"
     CDS             28955..29335
                     /locus_tag="VWX69_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9191883.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            29585..30385
                     /locus_tag="VWX69_000487"
     CDS             29585..30385
                     /locus_tag="VWX69_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU9191884.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            30396..31334
                     /locus_tag="VWX69_000488"
     CDS             30396..31334
                     /locus_tag="VWX69_000488"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU9191885.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKVTNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            31376..33277
                     /locus_tag="VWX69_000489"
     CDS             31376..33277
                     /locus_tag="VWX69_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU9191886.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKTTNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(33338..34993)
                     /gene="pavA"
                     /locus_tag="VWX69_000490"
     CDS             complement(33338..34993)
                     /gene="pavA"
                     /locus_tag="VWX69_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU9191887.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIGLDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            35098..35595
                     /gene="ybeY"
                     /locus_tag="VWX69_000491"
     CDS             35098..35595
                     /gene="ybeY"
                     /locus_tag="VWX69_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU9191888.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHKLNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            35576..35971
                     /locus_tag="VWX69_000492"
     CDS             35576..35971
                     /locus_tag="VWX69_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU9191889.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            35988..36887
                     /gene="era"
                     /locus_tag="VWX69_000493"
     CDS             35988..36887
                     /gene="era"
                     /locus_tag="VWX69_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU9191890.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            36936..37760
                     /gene="mutM"
                     /locus_tag="VWX69_000494"
     CDS             36936..37760
                     /gene="mutM"
                     /locus_tag="VWX69_000494"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU9191891.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            37760..38365
                     /locus_tag="VWX69_000495"
     CDS             37760..38365
                     /locus_tag="VWX69_000495"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU9191892.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            38352..39551
                     /locus_tag="VWX69_000496"
     CDS             38352..39551
                     /locus_tag="VWX69_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEU9191893.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            39551..39700
                     /gene="rpmG"
                     /locus_tag="VWX69_000497"
     CDS             39551..39700
                     /gene="rpmG"
                     /locus_tag="VWX69_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9191894.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            39740..39973
                     /gene="secG"
                     /locus_tag="VWX69_000498"
     CDS             39740..39973
                     /gene="secG"
                     /locus_tag="VWX69_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU9191895.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            40075..42429
                     /gene="rnr"
                     /locus_tag="VWX69_000499"
     CDS             40075..42429
                     /gene="rnr"
                     /locus_tag="VWX69_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU9191896.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNH
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYVDVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            42392..42859
                     /gene="smpB"
                     /locus_tag="VWX69_000500"
     CDS             42392..42859
                     /gene="smpB"
                     /locus_tag="VWX69_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU9191897.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            42875..43735
                     /gene="tehB"
                     /locus_tag="VWX69_000501"
     CDS             42875..43735
                     /gene="tehB"
                     /locus_tag="VWX69_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU9191898.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            43808..44761
                     /gene="coiA"
                     /locus_tag="VWX69_000502"
     CDS             43808..44761
                     /gene="coiA"
                     /locus_tag="VWX69_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU9191899.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            44780..46582
                     /gene="pepF"
                     /locus_tag="VWX69_000503"
     CDS             44780..46582
                     /gene="pepF"
                     /locus_tag="VWX69_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9191900.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            46584..47297
                     /locus_tag="VWX69_000504"
     CDS             46584..47297
                     /locus_tag="VWX69_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU9191901.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            47364..48305
                     /gene="prsA"
                     /locus_tag="VWX69_000505"
     CDS             47364..48305
                     /gene="prsA"
                     /locus_tag="VWX69_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU9191902.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(48422..48763)
                     /locus_tag="VWX69_000506"
                     /pseudo
     CDS             complement(48422..48763)
                     /locus_tag="VWX69_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            49177..49272
                     /locus_tag="VWX69_000507"
                     /pseudo
     CDS             49177..49272
                     /locus_tag="VWX69_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(49526..50146)
                     /locus_tag="VWX69_000508"
     CDS             complement(49526..50146)
                     /locus_tag="VWX69_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9191903.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(50146..50628)
                     /locus_tag="VWX69_000509"
     CDS             complement(50146..50628)
                     /locus_tag="VWX69_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU9191904.1"
                     /translation="MAKKVKIKKTLAEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(50628..51470)
                     /locus_tag="VWX69_000510"
     CDS             complement(50628..51470)
                     /locus_tag="VWX69_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU9191905.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(51565..52365)
                     /locus_tag="VWX69_000511"
     CDS             complement(51565..52365)
                     /locus_tag="VWX69_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU9191906.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            52509..53888
                     /gene="glmU"
                     /locus_tag="VWX69_000512"
     CDS             52509..53888
                     /gene="glmU"
                     /locus_tag="VWX69_000512"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU9191907.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            53898..54443
                     /locus_tag="VWX69_000513"
     CDS             53898..54443
                     /locus_tag="VWX69_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9191908.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            54455..54769
                     /locus_tag="VWX69_000514"
     CDS             54455..54769
                     /locus_tag="VWX69_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU9191909.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            54786..55478
                     /locus_tag="VWX69_000515"
     CDS             54786..55478
                     /locus_tag="VWX69_000515"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU9191910.1"
                     /translation="MKIGIIAAMPEELAYLVQHLYNVQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            55555..56046
                     /gene="rocS"
                     /locus_tag="VWX69_000516"
     CDS             55555..56046
                     /gene="rocS"
                     /locus_tag="VWX69_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU9191911.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            56144..56734
                     /locus_tag="VWX69_000517"
     CDS             56144..56734
                     /locus_tag="VWX69_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU9191912.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            56743..58506
                     /locus_tag="VWX69_000518"
     CDS             56743..58506
                     /locus_tag="VWX69_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU9191913.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASFFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT        17771 a        10559 c        13168 g        17169 t
ORIGIN      
        1 gatacaaggt ggagcagatt catatggtaa aaatcctaat ggtaggtacg attgggaaat
       61 agaaccagta ttaactctgc cggttcatgg attttgttcc agaggcacct atgatttagg
      121 atatattgga ggaggcaatc atctttgcaa aggaagtgct gcgagatttt aagtaaaatt
      181 tattagtaat atgaagaaac aagtggagaa agcagagaat ttaatatgaa aaaacgggct
      241 attcaaattt tactagcatt gtccttaatt ttttacaaat caacttggtt ttggagagtt
      301 ttcaatcacc tcgcaaagcc ctatctacca gcaagtcgtg aattttttca gattctgctt
      361 ttgatggaga gcggagttct tttcttagcg gtcatctatc tactggtttt tgcaggaaag
      421 aaaatttttc atttcaagtg gcagctgagg tacttcatct accttttact gggctacatc
      481 atttcatata tgtctgactt cctcttttcg tatttcatat ccctgtcttc aaatcagatt
      541 tctttgaatg aaacgataga aatgatgggg agacaggagt tcccttattt cttgctcatc
      601 gtttgcttca tcgcccctat tgctgaggaa ttgatttatc gaggtgtgct tatgacaacc
      661 tttttcaaaa actcaccttg gtacggagat gttttgcttt ctgctattat tttcggttat
      721 attcatatca attttgcttt aactcctctt gcttttttca tttatgctag tggaggtctg
      781 attttagctc tattgtatcg catgactaaa aatctctact atccaatact agttcatatt
      841 ctcatcaata tcactgcctt ctgggatgtt tggttactcc tattttcagg aagttagctt
      901 actaaaaaaa tgtcggaatt ttccggcatt ttcttttttc acaaatagtc aacgtttttc
      961 tttccgatac tgaagtggtg tgtagccact tatttttttg aattgatttt gaaaataaga
     1021 ttggcgtgag aaaggcagat agtgaagata gttaagaaga ataggatgtt cttttttcct
     1081 ttttggaaaa cttctaaaat atggtataat gaaaagataa agaagttggg ggtagaagat
     1141 gaacattcaa caattacgct atgttgtggc tattgccaat agtggtactt ttcgtgaagc
     1201 tgctgaaaag atgtatgtta gtcagccgag tctgtctatt tctgttcgtg atttggaaaa
     1261 agagttgggc tttaagattt tccgtcggac cagctcaggg actttcttga cccgtcgtgg
     1321 gatggaattt tatgaaaaag cgcaagaatt ggttaaagga tttgatattt ttcaaaatca
     1381 gtatgccaat cctgaagaag aaaaagatga attttccgtt gctagccagc actatgactt
     1441 cttaccacca actattacgg ccttttcaga gcgctatcct gactataaga acttccgtat
     1501 ttttgaatca actactgttc aaatattaga tgaagtggcg caagggcata gtgagattgg
     1561 gattatctac ctcaacaatc aaaataaaaa ggggattatg caacgggttg aaaagttagg
     1621 tctggaggtc atcgaattga ttcctttcca tacccatatt tatctctgtg agggtcatcc
     1681 tttagcccag aaagaggaat tagtcatgga ggatttagcg gatttaccaa cggttcgttt
     1741 cactcaagag aaagacgagt acctttatta ttcagagaac tttgtcgata ccagcgctag
     1801 ctcacagatg tttaatgtga cagaccgtgc caccttgaat ggtattttgg agcggacgga
     1861 cgcctatgcg acaggttctg gatttttaga tagtgacagt gttaatggca ttacagttat
     1921 tcgtctcaag gataacctag ataaccgcat ggtctatgtt aaacgtgaag aagtggagct
     1981 tagtcaagct gggactctct tcgtagaagt catgcaagaa tattttgatc aaaagaggaa
     2041 atcatgaaaa aaagagcaat agtggcagtc attgtactgc ttttaattgg gctggatcag
     2101 ttggtcaaat cttatatcgt ccagcagatt ccactgggtg aagtgcgctc ctggatcccc
     2161 aatttcgtta gcttgaccta cctgcaaaat cgaggtgcag ccttttctat cttacaagat
     2221 cagcagttgt tattcgctgt cattactctg gttgtcgtga taggtgccat ttggtattta
     2281 cataaacaca tggaggactc attctggatg gtcttgggtt tgactctaat aatcgcgggt
     2341 ggtcttggaa actttattga cagggtcagt cagggctttg ttgtggatat gttccacctt
     2401 gactttatca actttgcaat tttcaatgtg gcagatagct atctgacggt tggagtgatt
     2461 attttattga ttgcaatgct aaaagaggaa ataaatggaa attaaaattg aaactggtgg
     2521 tctgcgtttg gataaggctt tgtcagattt gtcagaatta tcacgtagtc tcgcgaatga
     2581 acaaattaaa tcaggccagg tcttggtcaa tggtcaagtc aagaaagcta aatacacagt
     2641 ccaagagggt gatgtcgtca cttaccatgt gccagaacca gaggtattag agtatgtggc
     2701 tgaggatctt ccgctagaaa tagtctacca agatgaggat gtggctgtcg ttaacaaacc
     2761 tcagggaatg gttgtgcacc cgagtgctgg tcataccagt ggaaccctag taaatgccct
     2821 catgtatcat attaaggact tgtcgggtat caatggggtt ctgcgtccag ggattgttca
     2881 ccgtattgat aaggatacgt caggtcttct catgattgct aaaaacgatg atgcgcatct
     2941 agtacttgcc caagaactca aagataaaaa gtctctccgc aaatattggg cgattgttca
     3001 tggaaatctg cctaatgatc gtggtgtaat tgaagcgccg attggccgga gtgaaaaaga
     3061 ccgtaagaaa caggctgtaa ctgctaaagg gaagcctgca gtgacgcgtt ttcacgtctt
     3121 ggaacgcttt ggcgattata gcttagtaga gttgcaactg gagacagggc gcactcatca
     3181 aatccgtgtc cacatggctt atatcggcca ttcagtcgct ggtgatgagg tctatggtcc
     3241 tcgcaagact ttgaaaggac atggacaatt tcttcatgcc aagactttag gttttactca
     3301 tccgagaaca ggtaagacct tggaatttaa agcagatatc ccagagattt ttaaggaaac
     3361 cttggagaga ttgagaaagt aagaatgaaa aagaaattaa ctagtttagc acttgtaggc
     3421 gcttttttag gtttgtcatg gtatgggaat gttcaggctc aagaaagttc aggaaataaa
     3481 atccacttta tcaatgttca agaaggtggc agtgatgcga ttattcttga aagcaatgga
     3541 cattttgcca tggtggatac aggagaagat tatgatttcc cagatggaag tgattctcgc
     3601 tatccatgga gagaaggaat tgaaacgtct tataagcatg ttctaacaga ccgtgtcttt
     3661 cgtcgtttga aggaattggg tgtccaaaaa cttgatttta ttttggtgac ccatacccac
     3721 agtgatcata ttggaaatgt tgatgaatta ctgtctacct atccagttga ccgagtctat
     3781 cttaagaaat atagtgatag tcgtattact aattctgaac gtctatggga taatctgtat
     3841 ggctatgata aggttttaca gactgctgca gaaaaaggtg tttcagttat tcaaaatatc
     3901 acacaagggg atgctcattt tcagtttggg gacatggata ttcagctcta taattatgaa
     3961 aatgaaactg attcatcggg tgaattaaag aaaatttggg atgacaattc caattccttg
     4021 attagcgtgg tgaaagtcaa tggcaagaaa atttaccttg ggggcgattt agataatgtt
     4081 catggagcag aagacaagta tggtcctctc attggaaaag ttgatttgat gaagtttaat
     4141 catcaccatg ataccaacaa atcaaatacc aaggatttca ttaaaaattt gagtccgagt
     4201 ttgattgttc aaacttcgga tagtctacct tggaaaaatg gtgttgatag tgagtatgtt
     4261 aattggctca aagaacgagg aattgagaga atcaatgcag ccagcaaaga ctatgatgca
     4321 acagtttttg atattcgaca agacggttta gtaaacattt caacttccta caagccgatt
     4381 ccaagttttc aagctggttg gcataagagt tcatatggaa actggtggta tcaagcgcct
     4441 gattctacag gagaatatgc tgtcggttgg aatgaaatta agggtgaatg gtattacttt
     4501 aaccaaacgg gtatcttatt acagaatcaa tggaaaaaat ggaacaatcg ttggttctat
     4561 ttgacagact ctggtgttgc tgctaaaaat tggaagaaaa tcgctggaat ctggtattat
     4621 tttaacaaag aaaaccagat ggaaattggt tggattcaag ataaagagca gtggtattat
     4681 ttggatgttg atggctctat gaagacaggt tggcttcaat ataaggggca atggtattac
     4741 tttgctccat caggggaaat gaaaacgggc tgggtaaaag ataaagaagc ctggtactat
     4801 atggattcta ctggtatcat gaagacaggt gagatagaag ttgctagaca tcattactat
     4861 ctagaagaat caggagctat gaagcaaggc tggcttaaaa aggcaaatga ttggtatttc
     4921 tacaagacag atggttcacg agctataggt tggattaaag acaaggataa atggtacttc
     4981 ttgaaagaaa atggtcaatt acttgtgaat ggtaagacac cagaaggcta tactgtggat
     5041 tcaagtggtg cctggttagt ggatgttccg atcgagaaat ctgctacaat taaaactaca
     5101 agtcattcag aaataaaaga atccaaagaa gtagtgaaaa aggatcttga aaataaagaa
     5161 acgagtcaac atgaaagtgt tacaaattct tcaactagtc aagatttgac atcctcaact
     5221 tcacaaagct ctgaaacgag tgtaaacaaa tcggaatcag aacagtagta gaaaagaagg
     5281 ttttagggcc ttctttttcc tatcaactct tttctatttc ctgttattca tgttataatg
     5341 gataaatatg aataatcgga gtgagactat gaaatacaaa cggattgtct ttaaggtggg
     5401 tacttcttct ctgacaaatg aggatggaag tttatcacgt agtaaggtaa aggatattac
     5461 ccagcagttg gctatgctgc acgaggctgg tcatgagttg attttggtgt cttcaggtgc
     5521 cattgcggct ggttttggag ccttaggatt taaaaagcgt ccgactaaaa ttgctgataa
     5581 acaggcttca gcagcggtag ggcagggact tttgttggaa gaatatacga ccaatcttct
     5641 cttgcgtcaa atcgtttctg cacaaatctt gctgacccaa gatgactttg tggataagcg
     5701 tcgttataaa aatgcccatc aggctttgtc ggttttgctc aaccgtgggg caattcctat
     5761 catcaatgag aatgatagtg tcgttattga tgagctcaag gttggggaca atgacactct
     5821 aagtgctcaa gtagcggcga tggtccaagc agacctttta gttttcttga cagatgtgga
     5881 cggtctctat actggaaatc ctaattcaga tccaagagcc aaacgcttgg agagaatcga
     5941 gaccatcaat cgtgagatta ttgatatggc tggtggagct ggttcgtcaa acggaactgg
     6001 gggtatgtta accaaaatca aggctgcaac tatcgcgacg gaatcaggag ttcctgttta
     6061 tatctgctca tccttgaaat cagattccat gattgaggcg gcagaggaga ccgaggatgg
     6121 ttcttacttt gttgctcaag agaaggggct tcgtacccag aaacaatggc ttgccttcta
     6181 tgctcagagt caaggttcta tttgggttga taaaggggct gcggaagctc tctctcaaca
     6241 tggaaagagt cttctcttat ctggtatcgt tgaagcagaa ggagtctttt cttacggtga
     6301 tatcgtgaca gtatttgata aggaaagtgg aaaatcactt ggaaaaggac gcgtgcaatt
     6361 tggagcatct gctttggagg atatgttgcg ttctcaaaaa gccaagggtg tcttgattta
     6421 ccgtgacgac tggatttcca ttactcctga aatccaacta ctttttacag aattttagag
     6481 gtaaactatg gtgagtagac aagaacaatt tgaacaggta caggctgtta aaaaatcgat
     6541 taacacagct agtgaagaag tgaaaaacca agccttgcta gccatggctg atcacttagt
     6601 ggctgctact gaggaaattt tagcggctaa tgccctcgat atggcagcgg ctaaggggaa
     6661 aatctcagat gtgatgttgg atcgtcttta tttggatgca gatcgtatag aagcgatggc
     6721 aagaggaatt cgtgaagtgg ttgccttacc agatccaatc ggtgaagttt tagaaacaag
     6781 tcagcttgaa aatggtttgg ttatcacaaa aaaacgtgta gctatgggtg tcatcggtat
     6841 tatctatgaa agccgtccaa atgtgacgtc tgatgcggct gctttgactc ttaagagtgg
     6901 aaatgcggtt gttcttcgta gtggtaagga tgcctatcaa acaacccatg ccattgtcac
     6961 agccttgaag aagggcttgg agacgactac tattcatcca aatgtgattc aactggtgga
     7021 ggatactagc cgtgaaagta gttatgctat gatgaaggcc aagggctatc tagaccttct
     7081 cattcctcgt ggaggagctg gcttgatcaa tgcagtggtt gagaatgcga ttgtacctgt
     7141 tatcgagaca gggactggga ttgtccatgt ctatgtggat aaggatgcag acgaagacaa
     7201 ggcgctgtct atcatcaaca atgctaaaac cagtcgtcct tctgtttgta atgccatgga
     7261 ggttctgctg gttcatgaaa acaaggcagc aagcatcctt cctcgcttgg atcaaatgct
     7321 ggttgcagat cgaaaagaag ctgggttgga accaattcaa ttccgcctag atagcaaagc
     7381 aagccagttt gtttcaggtc aagctgctca agcacaagac tttgataccg agtttttaga
     7441 ctatattcta gctgttaagg ttgtgagcag tttagaagaa gcggttgcgc atattgaatc
     7501 ccacagtacc catcattcgg atgctattgt gacggaaaat gctgaagctg cagcatactt
     7561 tacagatcaa gtggactctg cagcggtgta tgttaatgcc tcaactcgtt tcacagatgg
     7621 aggacaattt ggtcttggtt gtgaaatggg gatttctact cagaaattgc acgcgcgtgg
     7681 tccaatgggc ttgaaagagt tgaccagcta caagtatgtg gttgctggtg atgggcagat
     7741 aagggagtaa gagatgaaga ttggatttat cggtttgggg aatatgggtg ctagcttggc
     7801 aaaatctgtc ttgcagacta ggacgtcaga tgagattctc cttgccaatc gtagtcaagc
     7861 taaggtagat gctttcattg cagactttgg tggtcaggct tccagcaatg aagaaatgtt
     7921 tgcagaagca gatgtgattt ttctaggagt taagcctgct cagttttctg aactgctttc
     7981 tcaatatcag accatccttg aaaaaagaga aagtcttctt ttgatttcga tggcagctgg
     8041 attgacctta gaaaaactag caagtcttat cccaagccaa caccgaatta ttcgtatgat
     8101 gcctaatacc cctgcttcta tcgggcaagg agtgattagt tatgccttgt ctcctaattg
     8161 cagggctgag gacagtgaga tcttttgtca gcttttagcc aaggctggtc tcttggttga
     8221 attaggagaa agcttaatca atgcagcgac aggtcttgca ggttgtggac cagcctttgt
     8281 ctatctcttt attgaggcct tggcagatgc aggtgttcag acgggattac cacgagaaac
     8341 agccttgaaa atggcagccc aaactgtggt aggagctggg caattggtcc tagaaagcca
     8401 gcaacatcct ggagttttga aagatcaagt ttgtagtcca ggcggttcga ctattgctgg
     8461 cgtagcaagc ttagaagcgc atgcttttcg aggcatagtc atggaggcag ttcatcaagc
     8521 ctataaacga acacaagaac taggtaaata agaggtagct ttgactgcct cttttatggt
     8581 ggctgaaatg agaagacaca aaaagattgt cacaaactcc tatttttttg atagaataga
     8641 agtagtaaaa aagaaatgag ttagacatgt caaaaggatt tttagtctct cttgagggac
     8701 cagagggagc aggcaagacc agtgttttag aggctctgct accaatttta gaggaaaaag
     8761 gagtagaggt gctgacgacc cgtgaacctg gcggagtctt gattggggag aagattcggg
     8821 aagtgatttt ggatccaagt catactcaga tggatgctaa aacagagcta cttctctata
     8881 ttgccagtcg cagacagcat ttggtggaaa aagttcttcc agcccttgaa gctggcaagt
     8941 tggtcatcat ggatcgtttt atcgatagtt ctgttgccta tcagggattt ggtcgtggct
     9001 tagatattga agccattgac tggctcaatc agtttgcgac agatggcctc aaacccgatt
     9061 tgacactcta ttttgacatc gaggtggaag aagggctggc tcgtattgct gctaatagtg
     9121 accgcgaggt taatcgtttg gatttggaag ggttggactt gcataaaaaa gttcgtcaag
     9181 gctacctttc tcttctggat aaagagggaa atcgcattgt caagattgat gctagtctcc
     9241 ctttggagca agttgtggaa actaccaatg ctgtcttgtt tgacggaatg ggcttggcca
     9301 aatgaaacaa gatcaactaa aggcttggca accagctcag tttgaccgtt ttgtccgtat
     9361 cttagaacaa gaccagctca atcacgccta tctcttttca ggtttctttg gaagcttgga
     9421 aatggcgcaa tttttagcta agagcctttt ttgtacggat aaagttggcg tcttaccatg
     9481 tgagaaatgc cgaagttgca agctgattga acaggaagag tttccagatg tcaccttgat
     9541 taagccagtc aatcaggtca tcaagacaga acgtattcgg gaattggtgg gacagttttc
     9601 tcaagcaggg attgaaagcc agcaacaggt ctttatcatc gagcaagcgg ataaaatgca
     9661 tcccaacgca gccaattctc tgctcaaggt catcgaagaa ccccagagtg aagtttatat
     9721 tttcttcttg actagcgatg aggaaaagat gttaccgaca atccgaagtc ggactcagat
     9781 cttccacttt aaaaagcaag aagaaaaact tatcttactc ttagaacaaa tgggacttgt
     9841 taagaaaaaa gcgactcttt tagctaagtt tagtcaatcg cgagctgaag cagaaaagtt
     9901 ggcacatcag gcaagttttt ggaccttggt cgatgaaagt gaacgcctgc tgacttggtt
     9961 agtagctaag aaaaaagaaa gttatctaca ggttgccaaa ttagccaact tggcagatga
    10021 taaggaaaaa caggatcagg ttttacggat tcttgaagtt ctctgtgggc aggacctctt
    10081 gcaggtaaga gtaagagtga ttctacaaga tttactagaa gctagaaaaa tgtggcaagc
    10141 taatgtcagc tttcaaaatg ccatggaata tctggtcttg aaagaaatat aaactcaaaa
    10201 atgaatgata aagaaaggaa agggctgttt tatggacaaa aaagaattat ttgacgcgct
    10261 ggatgatttt tcccaacagt tattggtaac cttggccgat gtggaagcca tcaagaaaaa
    10321 tctcaagagc ctggtagagg aaaatacagc tcttcgtttg gaaaattcta agttgcgaga
    10381 acgcttgggt gaggtggaag cagatgctcc tgtcaaggcc aagcatgttc gtgaaagtgt
    10441 ccgtcgcatt taccgtgatg gatttcacgt atgtaatgat ttttatggac aacgtcgaga
    10501 gcaggacgag gaatgtatgt tttgtgacga gttgctatac agggagtagg catgcagatt
    10561 caaaaaagtt ttaaggggca gtctccctat ggcaagctgt atctagtggc aacgccgatt
    10621 ggcaatctag atgatatgac ctttcgagct atccagacct tgaaagaagt agattggatt
    10681 gctgctgagg atacgcgcaa tacaggtctt ttgctcaagc attttgacat ttccaccaag
    10741 cagatcagtt ttcatgagca caatgccaag gaaaaaattc ctgatttgat tggtttcttg
    10801 aaagcagggc aaagtattgc tcaggtctct gatgccggtt tgcctagcat ttcagaccct
    10861 ggtcatgatt tagttaaggc agctattgag gaagaaattg cagttgtgac agttccaggt
    10921 gcctctgcag gaatttctgc cttgattgcc agtggtttag cgccacagcc acatatcttt
    10981 tacggttttt taccgagaaa atcaggtcag cagaagcaat tttttggctt gaaaaaagat
    11041 tatcctgaaa cacagatttt ttatgaatca cctcatcgtg tagcagacac gttggaaaat
    11101 atgttagaag tctacggtga ccgctccgtt gtcttggtca gggaattgac caaaatctat
    11161 gaagaatacc aacgaggtac tatctctgag ttattagaaa gcattgctga aacgccactc
    11221 aagggcgaat gtcttctcat tgttgagggt gccagtcagg gtgtggagga aaaggacgag
    11281 gaagacttgt tcgtagaaat tcaaacccgc atccagcaag gtatgaagaa aaatcaagct
    11341 attaaggaag tagctaagat ttaccagtgg aataagagtc aactctacgc tgcctaccac
    11401 gactgggaag aaaaacaata aagggagata ggatgtaata attctgtctg tttctgttta
    11461 acttaattag tgatgataat ataaagatgt atcacttggt atagaagctt tggtattaag
    11521 ttttttatta agcccatacg gaataccgat ggttggagca gcagttatag cgttcttaga
    11581 aggtataaat agaaaaataa ggtcatttta aatcaaagga ttgataaatc agaaagaagg
    11641 tgattttttg cgaacatacg aaaataaaga agaactaaaa gctgagatag agaaaacatt
    11701 tgagaaatat attttagaat ttgataatat tccagaaaat ttaaaagata agagagctga
    11761 tgaagttgac agaactccag cagaaaacct tgcttatcag gttggttgga ccaacttggt
    11821 tcttaaatgg gaagaagatg aaagaaaggg gcttcaagta aaaacaccat cggataaatt
    11881 taaatggaat caacttggtg aattatatca gtggttcaca gatacctacg ctcatttatc
    11941 tctgcaagag ttgaaagcaa aattaaatga aaatattaat tctatctctg caatgattga
    12001 ttcgttgagt gaggaagaat tatttgaacc gcatatgaga aagtgggctg atgaagcgac
    12061 taaaacagcg acttgggaag tgtataagtt tattcatgta aatacggttg caccttttgg
    12121 aactttcaga actaaaatca gaaaatggaa gaagatagta ttataaatta tatttttaac
    12181 tttaaaaaat ttcataaaaa tggttaccaa aggcgataga agaaaaacta tcgtcttttt
    12241 ctttgcaaat ttttaagaag ggaggtgatc ttgcatggac tttgaatatt tttataacag
    12301 agaagcggaa agatttaact tcttaaaagt accggagata ttagttgata gagaagaatt
    12361 tcggggctta tcagcagaag caattatcct ttattccata cttcttaaac ggacaggaat
    12421 gtcatttaag aataactgga tagacaagga aggcagagta tttatctatt ttactgtcga
    12481 agaaattatg aaaagaagaa atatctcaaa gccaactgcc ataaaaacat tagatgagct
    12541 tgatgtaaaa aaaaggaata ggactgatcg aaagagtaag gcttggactt ggtaagccga
    12601 acatcattta tgttaaagac tttatgagta tatttcaggt aaaagaaaat gacttacaaa
    12661 agtcaaaaaa cttaacttca gaagtaaaag attttaacct cagaagtaaa gaaaatgaac
    12721 ttcaagaggt taagaacctt gactctaact atatagagaa taataagagt aagtatagta
    12781 agagagaata tagttttggt gaaaacggac ttggaacatt tcaaaatgtg tttttagctg
    12841 ttgaagatat atcggattta caaatcataa tgaactcaca gcttgagaat tacattagac
    12901 ttcctgcaaa actagaatcc tagttcatga ttgataatac cagcaatcaa attcattcgt
    12961 aatccgaagc gtttacgatg atttcgatag gttgttgaaa acattttaaa cgtttttact
    13021 ttggcaaaga tgttctcaac cttgcttctt tccttagata gcgcatggtt ataggcttta
    13081 tcttcagcta ttagcgactt gagtttgctg gatttacgtg gagtttgtac ttgaggatat
    13141 atcttcatga gcccttgata accactgtca gccaagattt taccagcttg tccgatattt
    13201 ctgcaactca ttttgaacaa cttcatatca cgacaatagt tcacagtgat atccaaagaa
    13261 acaattctcc cttgacttgt gacaatcgct tgagccttca tagcgtggca tttcttttta
    13321 ccagaatcat tcgctaattc tttttttagg gcgattgatt tgtacttccg tcgcatcaat
    13381 cattaccgtg tcctcagagc tgagaggagt tcttgaaacc gtaacaccac tttgaacaag
    13441 agttacttca acccattggc tccgacggat aaagttgctt tcgtgaatac caaaatcagc
    13501 cgcaatttgt tcataagttc gatattctcg cactattgaa gagtggccat aagaaggtct
    13561 tctaggctta atttaggttt tcgtccacct tttgcgtgtt taagttgata agctgttttt
    13621 aatacagcta atatctcttc aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt
    13681 gcatcagtta gttgtttact tgcttcatca ttcatagaac tactatacca tattttgttt
    13741 cgcaggaagt ctattggaaa gtaagaaata ttgaagctga ggctattaga agaaattgtg
    13801 agcgtggtgc tattttttca ggtaaaataa aatatcacga agattcacag tttaaaggag
    13861 atcactatgt tgaatgttat gctgttttag ataatacggt tatagcaaga gatagaataa
    13921 cagtccctat cgatccgtta tgtggaaaag attttataga gtagcatata attgattctt
    13981 aactggaata ctctttatct ctttacatca agaaaatgac taaacaggga agtttgcctt
    14041 cttccctttt tttgttatac tagtagaaga aaaaaataga aagatttgtg ggagtgaaaa
    14101 agtcctgtgg actttttcag cctgagccaa gaaactcgaa agctcgtaag tctgattggc
    14161 tttttcaatg tgaatcttaa cttcatactc ccaaagaggt attagtgtcg tgtctcaatc
    14221 ttatatcaat gttatcggtg ctggtttggc aggttctgaa gcagcctacc aaatcgcaga
    14281 gcgtggtatt ccagttaaac tttatgaaat gcgtggtgtc aagtcaacac ctcagcacaa
    14341 aacagacaat tttgctgagt tggtttgttc caattccttg cgtggagatg ctttgacaaa
    14401 tgctgttggc ctccttaagg aagaaatgcg tcgcttgggt tctgtgattt tggaatctgc
    14461 tgaggctaca cgtgttcctg caggtggtgc ccttgcagtg gaccgtgatg gtttctctca
    14521 aatggtgacc gaaaaagttg ccaaccaccc cttgattgaa gtggttcgtg atgaaattac
    14581 agaattgccg acagatgtta ttacggttat cgctactggt cctttgacaa gtgatgcctt
    14641 ggctgaaaag attcatgccc ttaatgacgg tgatggtttt tatttctacg atgcggcagc
    14701 gcctattatc gatgtcaaca ctatcgatat gagcaaggtc tacctcaaat cacgttatga
    14761 taagggagaa gcggcctacc tcaatgcccc tatgaccaag caagaattta tggatttcca
    14821 tgaagctttg gtcaatgcag aagaagcacc gcttaattct tttgaaaaag aaaagtactt
    14881 tgaaggatgt atgcctatcg aagtcatggc caaacgtggc attaaaacca tgctttatgg
    14941 tcctatgaaa ccagttggtc ttgagtatcc ggacgactac acaggacctc gtgatggaga
    15001 atttaaaaca ccttatgcgg ttgtccagct ccgtcaggat aatgcagctg gtagcctata
    15061 caatattgtt ggtttccaga cccacctcaa atggggagaa caaaagcgtg tcttccaaat
    15121 gattccgggt cttgaaaatg cggagtttgt ccgttatggt gtcatgcatc gcaattctta
    15181 catggattca ccaaatcttc ttgagcagac ttaccgttcc aagaaacaac caaatctctt
    15241 ctttgctggt cagatgacgg gggtggaagg ctatgttgag tcggcggctt cgggcttagt
    15301 tgcgggaatt aacgcagctc gtctcttcaa ggaagaaagc gaggttattt tccccgagac
    15361 gacagcgatt ggaagcttag ctcattacat tacccatgcc gacagcaaac atttccaacc
    15421 aatgaatgtc aattttggga tcatcaagga gttggaaggc gagcgtatcc gtgataagaa
    15481 ggctcgttat gaaaaaattg cagagcgtgc ccttgccgac ttagaggaat ttttgactgt
    15541 ctaatttttt tgaaagaatt gctcatgata ctataaaaat cttagaaatt gtgataaaat
    15601 aggtaggatg aaagaaggag agtgaaaatg gcgaatccca agtataaacg tattttaatc
    15661 aagttatcag gtgaagccct tgccggtgaa cgtggcgtag ggattgatat ccaaacagtt
    15721 caaacaatcg caaaagagat tcaagaagtt catagcttag gtatcgaaat tgcccttgtt
    15781 attggtggag gaaatctttg gcgtggagaa cctgcagcag aagcaggtat ggaccgtgtt
    15841 caggcagatt acactggaat gcttgggact gttatgaatg ctcttgtgat ggcagattca
    15901 ttgcaacaag ttggggttga tacgcgtgta caaacagcta ttgctatgca acaagtggca
    15961 gagccttatg tccgtggacg tgcccttcgt caccttgaaa aaggccgtat cgttatcttt
    16021 ggtgctggaa ttggttcacc atacttctcg acagatacaa cagcggccct tcgtgcagct
    16081 gaaatcgaag cagatgccat cctcatggct aaaaatggcg tcgatggtgt gtacaatgcc
    16141 gatcctaaga aggacaagac agccgttaag tttgaagaat tgacccaccg tgatgttatc
    16201 aacaaaggtc ttcgtatcat ggactcaaca gcctcaaccc tctcaatgga caacgacatt
    16261 gacttggttg tcttcaacat gaaccaatca ggcaacatca aacgtgtcgt atttggtgaa
    16321 aatatcggaa caacagtttc aaataatatc gaagaaaagg aataagaaag aatatggcta
    16381 acgtaattat tgaaaaagct aaagagagaa tgacccaatc tcaccaatca cttgctcgtg
    16441 aatttggtgg tatccgtgct ggtcgtgcca atgcaagctt gcttgaccgt gtacatgtag
    16501 aatactatgg agtcgaaact cctcttaacc aaatcgcttc aattacgatt ccagaagcgc
    16561 gtgttttgtt ggtaacacca tttgacaagt cttcattgaa agacatcgaa cgtgccttga
    16621 acgcttctga tcttggtatc acaccggcta atgacggttc tgtgattcgc ttggttatcc
    16681 cagctcttac agaagaaact cgtcgtgacc ttgctaaaga agtgaagaag gtcggcgaaa
    16741 atgctaaagt ggctgtccgc aatatccgtc gcgatgctat ggacgaagct aagaaacaag
    16801 aaaaagcaaa agaaatcact gaagacgaat tgaagactct tgaaaaagat attcaaaaag
    16861 taacagacga tgctgttaaa cacatcgacg acatgactgc taacaaagag aaagaacttt
    16921 tggaagtcta aaaataaaca gaaaaactca gttggcattg ctggctgagt tttattcgaa
    16981 agaaggaaat atgaatacaa atcttgcaag ttttatcgtt ggactgatca tcgatgaaaa
    17041 tgaccgtttt tactttgtgc aaaaggatgg tcaaacctat gctcttgcta aggaagaagg
    17101 tcaacataca gtaggggata cggtcaaagg ttttgcatac acggatatga agcaaaaact
    17161 ccgcctgaca accttagaag tgactgccac tcaggaccaa tttggttggg gacgtgtcac
    17221 agaggttcgt aaggatttgg gtgtctttgt ggatacaggc cttcctgaca aggaaatcgt
    17281 tgtgtcactc gatattctcc ctgagctcaa ggaactctgg cctaagaagg gcgaccaact
    17341 ctacatccgt cttgaagtgg ataagaaaga ccgtatctgg ggcctcttgg cttatcaaga
    17401 agacttccaa cgtcttgctc gtcctgccta caacaacatg cagaaccaaa actggccagc
    17461 cattgtttac cgtctcaagc tgtcaggaac ttttgtttac ctaccagaaa ataatatgct
    17521 tggttttatt catcctagcg agcgttacgc agagccacgt ttggggcaag tattagatgc
    17581 gcgcgttatt ggtttccgtg aagtggaccg cactctgaac ctctccctca aaccacgctc
    17641 ctttgaaatg ttggaaaacg atgctcagat gattttgact tatttggaaa gtaatggcgg
    17701 tttcatgacc ttaaatgata agtcatctcc agacgacatc aaggcaacct ttggcatttc
    17761 taaaggtcag ttcaagaaag ctttaggtgg tcttatgaag gctggtaaaa tcaagcagga
    17821 ccagtttggg acagagttga tttagggagg cttatgagaa aatcatttta cacttggctc
    17881 atgaccgagc gcaatcctaa aagtaacagt cccaaagcaa ttttggcaga cctcgctttt
    17941 gaagaggcag cttttccaaa acatacagat gattttgatg aggtcagtcg ctttttggag
    18001 gagcatgcca gtttctcttt taacctagga gattttgaca gcatttggca ggaatatcta
    18061 gaacactagc atttattcat tgggtttggg ctagtaattt ctccatccct ctgctataat
    18121 aaaaagaaat aaaaggatta gagaggttct ttatttgaag gaacattcaa tagacattca
    18181 actgagtcat ccagatgacc tgtttcatct ttttggttcc aatgaacgcc atcttcgttt
    18241 gatggaagaa gagcttgatg ttgtgattca tgctcgtacg gagattgtcc aggttttggg
    18301 agaagagtct gcctgtgagg aagcccgtca agttattcag gctttgatgg tcttggtaaa
    18361 tcgtgggatg accgttggta cgccagatgt agtcactgcg attagcatgg tcaaaaatga
    18421 tgaaattgac aagtttgtcg ccctttacga agaagaaatt atcaaagata atactgggaa
    18481 acctatccgt gtcaaaaccc tagggcaaaa gctttatgtg gacagtgtca aacagcatga
    18541 tgtgaccttt ggaattgggc cagcaggtac agggaagacc ttccttgcag tgaccttggc
    18601 agtgactgcc cttaaacgtg ggcaagtcaa gcgaattatc ctaactcgtc cagcggtgga
    18661 agcgggagag agtcttggat ttcttccggg tgatcttaag gagaaggtgg atccttacct
    18721 tcgtcctgtt tacgatgcct tgtatcagat tctggggaaa gaccaaacaa ctcgactcat
    18781 ggagcgtgaa attatcgaga ttgcgcccct tgcctatatg cgtggacgga ccttggatga
    18841 tgcctttgtc attctcgatg aggcgcaaaa tacgaccatc atgcagatga agatgttctt
    18901 gactcgttta ggttttcatt ctaagatgat tgtcaatgga gatattagtc agattgacct
    18961 gccacgtaat gtcaagtccg gtttgattga tgctcaagag aaactcaaga acatccatca
    19021 gattgacttt gttcattttt cagccaagga tgtggttcgc catccagttg tcgctcagat
    19081 tatccgagcc tatgaatatt ctactgaagt tgcacacgac tgattttgag gaagtttgcc
    19141 tgcaaaagaa tatacttttg agagaggaaa atccagttgt ataggctaaa ggttttatcc
    19201 aaaggtttga gacaacgatt aggcacgatg gaaagaactt ttatgtggct gatgacgatc
    19261 agtgcatctt cctgtgtcat aatcacagtg cacaagaaag taggaatttg aaaagatgat
    19321 tgaccaacta tctaagtatt acagttgtag gatactaact gaaaaggata ttccaagtat
    19381 tttatcttta tatgaaagta atcctctgta ttttcagcat tgtccaccag agccaaattt
    19441 tgcaactgta aaagaggaca tgctttgtct acctgaaggt aaagctaagg ctgataagtt
    19501 ttttgttgga ttttggaatg gatctgacct tgtggctgtt atagattttg tctatgcaca
    19561 tcctgatgag gagactgttt ttattggttt gtttatggtt gatcaagcct atcagaggaa
    19621 agggattggt agtcatattg tgacagaagc actagcttat tttgctaaga actttcgaaa
    19681 ggcacgtttg gcttatgtta agggaaatcc gcaatctcag catttttggg aaaagcaggg
    19741 ctttaaatca attggatgcg aggttaagca agaactctat acggttgtta tcgctgaaca
    19801 gagcctagaa gattagaaat ggcatcaagt aagaactatt tggaatttgt tttggaacaa
    19861 ttatcaggat tagatgatgt gacttaccgt tccatgatgg gggagtatat tctttacttc
    19921 cgcggcaaga ttattggcgg catttatgac gatcgctttt tagttaaacc cgtgcaagca
    19981 gtcttagata agattgacca atcttctttt gagtttccat acaaaggtgc caaagaaatg
    20041 atttgagtgg aagaacttga taataagatg tttctataag acctgatttt agctatgtat
    20101 aaccaactgc caacgcccaa acctaaaaag aaaaagcaag ggtgaacgaa gtaaaaaaga
    20161 agtctgctaa ggccctgtct ttgcacgggt aaaattttat atataaaaag aagctgggac
    20221 taaagagctc agcttccttt ggtttatata attgtcatta caagacgaag tggttgggcg
    20281 aaactctgtt gactttattc aatttagagt ttcttatgca caattgagtc tggaacgaaa
    20341 gtctccagtt gcaaagtata cagtacaata aaccaacgat gtaatagctg atgacacaaa
    20401 gcacagtggg taggacttgc gaagtcaccc ttttcttttc aaaatttata ctaaatcatt
    20461 gatatcagtg tagtcacgat taagtccttg agcaactggt aggctagtca agtaaccttg
    20521 ataagtggtc acaccttgac gcaagccttc atcttcagag attgcttgtg cgaatccttt
    20581 gccagccaaa gcttcgatat aaggaagagt gacattggtt agggcgatgg ttgaagtgcg
    20641 ggcaaccgca ccagggatat tggcaacggc atagtggaga acaccgtgtt tttcatagac
    20701 gggttcatcg tgcgttgtca cacggtcagc tgtttcgata acgccacctt ggtcaacagc
    20761 aacgtcaacg atacagagcc tggacgcatt tgtttgacca tctcatctgt caccaattcc
    20821 ggtgcttttg caccagggat gagaatggct ccaatcacca catcagcatc tctcatactt
    20881 gcttcaatgt tgaatgaatt agatataaga gtttgaattt gacttccaaa gacttcttct
    20941 agaactgaga gacgcttggc actaatatct aaaatagtca cttgagcacc aagaccaagg
    21001 gcgatgcggg cagcatgtgt accgacgaca ccatcaccga tgatagttac ttttcctttt
    21061 ggaacacctg gtacaccact aggtagaaca ccagagccac cagcttgctt agtaaggaag
    21121 tgagctccga tttaaacagc catacgacct gcaacctcac tcataggaac gaggagcggt
    21181 agttgtcctt gattgtcacg aacagtttca taggcaattc ctgttgtttt tgctgctaac
    21241 atagcatctg ctaattctgg agcagcggcc atgtgcaagt aggtgaagag aagaagatcg
    21301 tcgcgcaagt aaccgtattc agaacttaaa ggttctttta ctttcacaac caactctgct
    21361 gcccaagctt caccagcagt agcgacaatc tcagctcctt gcttttgata gtcagcatca
    21421 gtaaagccag aaccgagacc agcatttgtt tcgataagga cacgatgacc acgactaact
    21481 aagctatgaa cacctgcagg tgtgagggcg acacggtttt cgttattttt aatttctttt
    21541 gggattccga ttaacattga gataacctac ctttcaattg acggtcttgt tttggttgtc
    21601 acattccagt tcataaatca aaaatgtgac ggtttcattg tatatgaaac cgcttcaaaa
    21661 atcaagaaaa acttgtcatc caaatttttt tatgctagac tagtgaaaat caagctctaa
    21721 tggagggaaa agtatggaat caatatttgt gaaatttgcc cagtatccgt ctatagaaac
    21781 ggagcgttta ttgcttagac ctgtaacttt ggatgatgcg gaagcaatgt ttgactatgc
    21841 ctcggacaag ggtaatacac gttacacttt tccaaccaat caaagcttgg aagaaaccaa
    21901 gaataacatt gctcagttct acttggctaa tcccttggga cgttggggga ttgaattaaa
    21961 agataacggc aagtttatcg gaactattga cttacacaag attgatcctg ttcttaagaa
    22021 ggcagctatt ggctacatta tcaataaaaa gtattggaat caaggattaa cgccagaaac
    22081 caatcgtgct gtgattgagc tagcttttga gaagatagga atgaataagt tagttgcttt
    22141 atacgataag gacaattctg cgtcaggaaa ggtcatggag aaatcaggca tgcgtttttc
    22201 ccatgcagaa ccatatgctt gtatggacca gcatgaaaaa ggccgaatcg tgacaagagt
    22261 tcattatgtc ttgaccaagg aagactattt tgcaaataaa taagcagttg aaaagaaatt
    22321 tttcgactgt tttttcttcc tcttacgaat aatctaagag aggagaaaat atggaagcaa
    22381 ttatcgagaa aatcaaagag tataaaatca tcgtcatctg tactggtctg ggcttgcttg
    22441 taggcggatt tttcctgcta aagccagctc cacaaacacc tgtaaaggaa acgaatttgc
    22501 aggctgaagt tgcagctgtt tccaaggatt tggtatccga aaaggaagtg aacaaggaag
    22561 agaaggaaga accccttgaa caagatctaa tcacagtaga tgtcaaaggt gctgtcaaat
    22621 cgccagggat ttatgacttg cctgtaggta gtcgagtcaa tgatgctgtt cagaaggctg
    22681 gtggcttgac agagcaagca gacagcaagt cgctcaatct agctcagaaa gttagtgatg
    22741 aggctctggt ttacgttcct actaagggag aagaagcagt tagtcaacag actggttcgg
    22801 ggacagcttc ttcaataagc aaggaaaaga aggtcaatct caacaaggcc agtctggaag
    22861 aactcaagca ggtcaaggga ctgggaggaa aacgagctca ggacattatc gaccatcgtg
    22921 aggcaaatgg caagttcaag tcagtagacg agctcaagaa ggtctctggc attggtggca
    22981 aaacaataga aaagcttaaa gactatgtta cagtggatta agaatttctc tattccccta
    23041 atttacctga gttttctatt actttggctt tattacgcta ttttctcagc atcttatctt
    23101 gctttgttgg gctttgtttt tctgctagtc tgtctcttta tccaatttcc gtggaaatct
    23161 gctggtaaag ttctaataat ttgcggaatc tttggatttt ggtttgtttt tcaaaattgg
    23221 caacagagtc aagcgagtca aaatctggcg gattctgttg aaagggtacg gattttgcct
    23281 gatactatta aggttaatgg tgatagtcta tcctttcgtg gcaagtctaa cggtcgtgct
    23341 ttccaagtct attataaact ccagtccgag gaggagaaag aagcctttca agctttaacc
    23401 gacctgcatg agataggact agaagggaag ctttcggagc cagaagggca gagaaatttt
    23461 ggtggcttta attaccaagc ctatctgaag actcagggaa tttaccagac tctcaatatc
    23521 aaaacaatcc agtcacttca aaagattggc agttgggata taggagaaaa cttgtccagt
    23581 ttacgtcgaa aggctgtggt ttggattaag acgcactttc cagaccctat gcgcaattac
    23641 atgacaggac tcttgctggg acatctggac accgactttg aggagatgaa tgagctttat
    23701 tccagtctag gaattatcca cctctttgcc ctatctggta tgcaggtagg ttttttcatg
    23761 aatggattta agaaacttct cttgcgattg ggcttgaccc aagaaaagtt gaaatggctg
    23821 acttatccct tttcccttat ctatgcggga ctaactggat tttcagcatc ggttattcgc
    23881 agtctcttgc aaaagctact ggctcaacat ggggttaagg gcttggataa ttttgccttg
    23941 acggtgcttg tcctctttat tgtcatgcca aactttttct tgacagcagg aggagtcttg
    24001 tcctgcgctt atgcttttat cctgaccatg accagcaaag aaggggaggg gctcaaggct
    24061 gttactagtg aaagtctagt catctccttg ggcatattgc ccattctatc cttctatttt
    24121 gcggaatttc aacctttgtc tatccttttg acctttgtct tttcctttct atttgacttg
    24181 accttcttac cgctcttgtc tattttattt gtcctttcct ttctctatcc agtcattcag
    24241 ctgaacttta tctttgaatg gttggagggc attattcgct tggtgtcaca ggtgacaagt
    24301 agacctctgg tctttggaca acccaatgca tggtttttaa tcctattgtt aatttccttg
    24361 gctttggtct atgatttgag aaaaaacatt aaaaagctaa cggtattgtg cttattgatt
    24421 acagggctct ttctcctgac caagcatcca ctggaaaatg aaatcaccat gctggatgtg
    24481 gggcaaggag aaagtatttt cctacgggat gtaactggga aaaccattct catagatgta
    24541 ggtggtaagg cagaatctta taagaaaatc gaaaaatggc aagaaaaaat gacgaccagc
    24601 aatgcccagc gaaccttgat tccctatctc aaaagtcgag gagtagctaa gattgaccag
    24661 ctaattttga ctaacacgga caaggagcat gttggagatt tgtcagaggt gaccaaggct
    24721 ttccatgtag gggagattct agtatcaaaa gacagtctga aacagaagga atttgtggca
    24781 gaactacagg cgactcaaac aaaggtgcgt agtatgacag taggggagaa cttgcccatt
    24841 tttggaagtc agttagaagt tctatctcca aggaaaatgg gagatggagg acacgatgat
    24901 accctagttc tgtatgggaa attcttggat aagcaatttc tcttcacggg aaatttggag
    24961 gagaaaggag agaaggactt gctgaagcac tatccagact tgaaagtaaa tgttttgaaa
    25021 gctagccaac atggcaataa aaaatcatca agtccagcct ttctagaaaa actcaaacca
    25081 gagcttactc ttatctcagt tggaaagagc aatcgaatga aactccccca tcaggaaaca
    25141 ttgacacgac tggaaggtat caatagcaaa gtttatcgaa ctgaccagca aggagctata
    25201 cgttttaagg ggttggatag ttggaaaatc gaaagtgttc gataggaagg ataaatgttg
    25261 tagattagtg aaataaacta aaaatttgtt gcataataat gataaaaatg gtataatgaa
    25321 aacgtattca atattgagga tataaaatca ttaaaaatta gcaaaaatcg tttaattagt
    25381 tagtttatga ttattggtct ttttcagtcc agtatatctg ctgtgacagt cactaaaagt
    25441 tacaagtatg attggaatac ggtttgggaa tatagtacca actatcacga ccatcagtat
    25501 gcttggattc cgtcatggtc tcgttatgac agctattctg agtatccagt tggttctggc
    25561 tggaactacg gtcgttatga gatcataaac tattacagcg gaggctatta attcttaaag
    25621 agtgagaaaa aggagggcta gatatgttgc agcttactca tgtgacctta aaaacgcgac
    25681 aagtcatctt gcaagatgtg gatttcacct ttaaaaaggg tagggtttat ggtcttcttg
    25741 ctatcaatgg ctctggaaag acgaccctgt tccgtgccat tagcaattta attcccataa
    25801 gtagtggaaa tatcgcagcc cctccttctt tattttatta tgagagtatt gaatggctgg
    25861 atggaaactt aagtgggatg gactaccttc gtcttatcaa aaacatctgg aagtcaggtc
    25921 tgaacttgag ggatgaaatc gcctattggg aaatgtctga ctatatcagt cttcccattc
    25981 gcaagtattc cttaggcatg aagcaacgct tggtgattgc catgtatttc ctcagtcagg
    26041 ccaaatgctg gctcatggat gagattacaa atggcttaga tgagtattat cgacagaagt
    26101 tttttgatag gctagcacaa atcgatagac aagaacagct ggttctttta agttcccact
    26161 ataaggaaga gttggttgat gtctgcgata gagtagtaac cattcatcag gggcagatag
    26221 aagaggttta gtttatgaaa gatgttagtc tatttttatt gaaaaaagtt ttcaaaagcc
    26281 gcttaaactg gattgtctta gctttatttg tatctgtact cggtgttacc ttttatttaa
    26341 atagtcagac tgcaaactca cacagcttgg agagcaggtt ggaaagtcgc attgcagcca
    26401 acgagagggc tatcaatgaa aatgaagaga aactctccca aatgtctgat accagctcgg
    26461 aggaatacca gtttgctaaa aataatttag acgtgcaaaa aaatcttttg acgcgaaaga
    26521 cagaaattct aactttacta aaagaagggc gctggaaaga agcctactat ttgcagtggc
    26581 aagatgaaga gaagaattat gaatttgtat caaatgaccc gactgctagc tctggcttaa
    26641 aaatgggggt tgaccgcgaa cggaagattt accaagccct gtatcccttg aacataaaag
    26701 cacatacttt agagtttccg acccacggga ttgatcagat tgtctggatt ttagaggtta
    26761 tcatcccaag cttgtttgtg gttgcgatta tttttatgct aacacaacta tttgcagaaa
    26821 gatatcaaaa tcatctggac acagctcact tatatcctgt ttcaaaagtg acatttgcaa
    26881 tatcctctct tggagttgga gtgggatatg taactgtgct gtttatcgga atctgtggct
    26941 tttcttttct agtgggaagt ctgataagtg gttttggaca gttagattat ccctacccga
    27001 tttatagctt agtgaatcaa gaggtaacta ttggaaagat gcaggatgta ttatttcctg
    27061 gcttgctctt agctttctta gcctttatcg tcattgtgga agttgtgtat ttgattgctt
    27121 actttttcaa gcaaaaaatg cctgtcctct ttctttcact cattgggatt gttggcttat
    27181 tgtttggcat ccaaaccatt cagcctcttc aaaagattgc acatctgatt ccctttactt
    27241 acttgcgttc agtggagatt ttatctggaa gattacctaa gcagattgat aatgtcgatc
    27301 taaattggag catggggatg gtcttacttc cttgcctgat tatccttttg ttagtgggga
    27361 ttctatttat cgaaagatgg ggaagttcac gtaaaaagga agtttttaaa gtttagtttt
    27421 cctataggga agctaaagaa aaactaacat agggagagaa tcaacttggt tctctctttt
    27481 tgattcgaaa accaaaccaa aatacaaaca caaacttttc aaaaaataac tttttatctt
    27541 gacaagagct agaaaacttg gtatcatata aaagttgaga aaagcagaag tgagagcttc
    27601 tcgccttgtg acattaagtt gcctggccct acggatgaaa agtttcgaag aaacgctatc
    27661 ataacgtgcg ggcttgtata tttacgagtc cgctattgtt tttctctaat aaaacaaaag
    27721 aggtgaaaac catagcaaag caagacttat tcatcaatga tgagattcgt gtacgtgaag
    27781 ttcgcttgat tggtcttgag ggagaacagc taggcatcaa gccactcagt gaagcgcaag
    27841 ctttggctga taacgctaat gttgacctag tattgattca accccaagcc aaaccgcctg
    27901 ttgcaaaaat tatggactac ggtaagttca aatttgagta ccagaagaag caaaaagaac
    27961 aacgtaaaaa acaaagcgtt gttactgtga aagaagttcg tctaagtcca acaattgaca
    28021 agggtgactt tgatacaaaa cttcgtaatg cacgtaagtt ccttgaaaaa ggaaataaag
    28081 ttaaggtatc tattcgcttt aagggtcgta tgattaccca taaagagatt ggtgcaaaag
    28141 ttttagccga gtttgctgaa gcaactcaag atattgccat catcgaacaa cgtgctaaaa
    28201 tggatggacg tcaaatgttc atgcaattgg cgccagcgac tgacaaaaaa taattgtcag
    28261 aaagttaaat aaaggagaaa aaatcatgcc aaaacaaaaa acacaccgcg catcagctaa
    28321 acgtttcaaa cgtacaggtt ctggtggact taaacgtttc cgtgcttaca cttctcaccg
    28381 tttccacgga aaaactaaga aacaacgtcg tcatcttcgt aaagcatcta tggtgcattc
    28441 aggagattac aaacgtatca aagcaatgct tactcgcttg aaataatagc ttgactgtaa
    28501 gtaaacaatt ctagaaaata tttggaggaa ataaaacatg gcacgtgtta aaggtggcgt
    28561 tgtatcacgc aaacgtcgta aacgtattct taaattagca aaaggttact atggagctaa
    28621 acacatcttg ttccgtactg caaaagaaca agtaatgaac tcttactact atgcataccg
    28681 tgaccgtcgt cagaaaaaac gtgacttccg caaattgtgg attactcgta tcaatgcggc
    28741 ggctcgtatg aacggacttt catactcaca attgatgcat ggtttgaaat tggctgagat
    28801 cgaagttaac cgtaaaatgc ttgctgactt ggctgttaac gatgcagtag ctttcacagc
    28861 tcttgcagat gcagctaaag caaaacttgg taaataacaa ctgatgagac tggaacagga
    28921 ttgtccagtc tttttaaaaa taaaggagaa agatatggct tcaaaaatgc tacacacttg
    28981 cttacgagta gaaaatcttg aaaaatcaat cgcattttat caagatgctt ttggttttaa
    29041 agaattgcgt cgcagagatt ttccagacca tgccttcacg attgtctatc taggtcttga
    29101 gggtgatgat tatgagttgg agttgactta taactacgat cacggtccgt atgtggttgg
    29161 tgatgggttt gcccatatcg ccctcagtac acctgatctt gaggcacttc atcaagaaca
    29221 cagtgcaaaa ggctatgaag tgactgagcc aaatggtcta ccaggaacta caccaaacta
    29281 ttactttgtt aaagaccctg atggatataa ggtcgaagtc attcgtgaaa aataatttcg
    29341 tgcaagttaa gtagaatatt cgttttctac ttgacttttt ttagctgaaa gagtatacta
    29401 ataaaaattc aacctttaag gggagtccag agagactcac aaggtgtcag ataaaagaat
    29461 agtgcaagtt tctagaggag accttttgag tgtgctctct tgtgttgtac gattttaact
    29521 gaggccttgc actagcaagg tcttttcttt atctggtccc cttaaaattt aaggaggaaa
    29581 agttatgaat ctcacatgta agaagcgttt gggtgtcatt cggttggaaa ccatgaaggt
    29641 ggttgcacaa gaggaaatcg cgccagcaat ctttgaatta gtcctagaag gagaaatggt
    29701 tgaagccatg cgagcaggcc aatttcttca tctgcgtgta ccagacgatg cccatctctt
    29761 acgtcgtcct atttcaattt cgtctattga caaggcaaac aagcagtgtc acctcattta
    29821 tcggattgag ggagctggga ctgcaatttt ttcaacctta agtcagggag acactcttga
    29881 tgtgatgggg cctcagggaa atggttttga cttgtctgac cttgatgagc agaatcaggt
    29941 tctccttgtt ggtggtggga ttggtgttcc acccttgctt gaggtggcca aggaattgca
    30001 tgaacgtgga gtgaaagtag tgacagtcct cggttttgct aataaggatg ctgttatttt
    30061 gaaaacggaa ttggctcagt atggtcaggt ctttgtaacg acagatgatg gttcttatgg
    30121 catcaaggga aatgtttccg ttgttatcaa tgatttagac agtcagtttg atgctgttta
    30181 ctcgtgtggg gctccaggaa tgatgaagta tatcaatcaa acctttgatg atcacccaag
    30241 agcctattta tctctggaat ctcgtatggc ttgtgggatg ggagcttgct atgcctgtgt
    30301 tctaaaagta ccagaaagcg agacggtcag ccaacgcgtc tgtgaagatg gtcctgtttt
    30361 ccgcacagga acagttgtat tataaggaga aaattatgac tacaaatcga ttacaagttt
    30421 ctctacctgg tttggatttg aaaaatccga ttattccagc atcaggctgt tttggctttg
    30481 gacaagagta tgccaagtac tatgatttag accttttagg ttctattatg atcaaggcga
    30541 caacccttga accacgtttt ggaaatccaa ctccaagagt ggcagagacg cctgctggta
    30601 tgctcaatgc aattggcttg caaaatcctg gtttagaggt tgttttggct gaaaagctac
    30661 cttggctgga aagagaatat ccaaatcttc ctattattgc caatgtagct ggtttttcaa
    30721 aacaagagta tgcagctgtt tctcatggga tttccaaggt aactaatgta aaagctatcg
    30781 agctcaatat ttcttgtccc aatgttgacc actgtaatca tggacttttg attggtcaag
    30841 atccagattt ggcttatgat gtggtgaaag cagctgtgga agcctcagaa gtgccagttt
    30901 atgtcaaatt aaccccgagt gtgaccgata tcgttactgt cgcaaaagct gcagaagatg
    30961 cgggagcaag tggcttgacc atgatcaata ctctggttgg aatgcgcttt gacctcaaaa
    31021 ccagaaaacc aatcttggcc aatggaacag gtggaatgtc aggtccagca gtctttccag
    31081 tagccctcaa actcatccgc caagtagccc aaacaacaga cctgcctatc attggaatgg
    31141 ggggagtgga ttcggctgaa gctgccctag aaatgtatct ggctggggca tctgctatcg
    31201 gagttggaac agctaacttt accaatcctt atgcctgccc tgacatcatc gaaaatttac
    31261 caaaagtcat ggataaatac ggtattagca gtctggaaga actccgtcag gaagtaaaag
    31321 agtctctgag gtaaactgca atcaatctgt tcttgatttt ttattagttt gtaatatgaa
    31381 tttaggagaa ttttggtaca ataaaataaa taagaacaga ggaagaaggt taatgaagaa
    31441 agtaagattt atttttttag ctctgctatt tttcttagct agtccagagg gtgcaatggc
    31501 tagtgatggt acttggcaag gaaaacagta tctgaaagaa gatggcagtc aagcagcgaa
    31561 tgagtgggtt tttgatactc attatcaatc ttggttctat ataaaagcag atgctaacta
    31621 tgctgaaaat gaatggctaa agcaaggtga cgactatttt tacctcaaat ctggtggcta
    31681 tatggccaaa tcagaatggg tagaagacaa gggagccttt tattatcttg accaagatgg
    31741 aaagatgaaa agaaatgctt gggtaggaac ttcctatgtt ggtgcaacag gtgccaaagt
    31801 aatagaagac tgggtctatg attctcaata cgatgcttgg ttttatatca aagcagatgg
    31861 acagcacgca gagaaagaat ggctccaaat taaagggaag gactattatt tcaaatccgg
    31921 tggttatcta ctgacaagtc agtggattaa tcaagcttat gtgaatgcta gtggtgccaa
    31981 agtacagcaa ggttggcttt ttgacaaaca ataccaatct tggttttaca tcaaagaaaa
    32041 tggaaactat gctgataaag aatggatttt cgagaatggt cactattatt atctaaaatc
    32101 cggtggctac atggcagcca atgaatggat ttgggataag gaatcttggt tttacctcaa
    32161 gtttgatggg aaaatagctg aaaaagaatg ggtctacgat tctcatagtc aagcttggta
    32221 ctacttcaaa tccggtggtt acatgacagc caatgaatgg atttgggata aggaatcttg
    32281 gttttacctc aagtctgatg gcaaaatggc tgaaaaagaa tgggtctacg attctcatag
    32341 tcaagcctgg tactacttca aatctggtgg ctacatggcg aaaaatgaga cagtagatgg
    32401 ttatcagctt ggaagcgatg gtaaatggct tggaggaaaa actacaaatg aaaatgctgc
    32461 ttactatcaa gtagtgcctg ttacagccaa tgtttatgat tcagatggtg aaaagctttc
    32521 ctatatatcg caaggtagtg tcgtatggct agataaggat agaaaaagtg atgacaagcg
    32581 cttggctatt actatttctg gtttgtcagg ctatatgaaa acagaagatt tacaagcgct
    32641 agatgctagt aaggacttta tcccttatta tgagagtgat ggccaccgtt tttatcacta
    32701 tgtggctcag aatgctagta tcccagtagc ttctcatctt tctgatatgg aagtaggcaa
    32761 gaaatattat tcggcagatg gcctgcattt tgatggtttt aagcttgaga atcccttcct
    32821 tttcaaagat ttaacagagg ctacaaacta cagtgctgaa gaattggata aggtatttag
    32881 tttgctaaac attaacaata gccttttgga gaacaagggc gctactttta aggaagccga
    32941 agaacattac catatcaatg ccctttatct ccttgcccat agtgccctag aaagtaactg
    33001 gggaagaagt aaaattgcca aagataagaa taatttcttt ggcattacag cctatgatac
    33061 gaccccttac ctttctgcta agacatttga tgatgtggat aagggaattt taggtgcaac
    33121 caagtggatt aaggaaaatt atatcgatag gggaagaact ttccttggaa acaaggcttc
    33181 tggtatgaat gtggaatatg cttcagaccc ttattggggc gaaaaaattg ctagtgtgat
    33241 gatgaaaatc aatgagaagc taggtggcaa agattagtac tataagtgaa tatgatttga
    33301 gtgaatagta agttaaaaat cctgatttca agtaaaatca ggattttttc atggatgcaa
    33361 tttttttgga gtctggtgtg acgcggaggg tcttttgtcc tgtgtaagtg acaaagccgg
    33421 gttttccacc agttggttta ttgagttttt tgacttcaat catatctacc tgcaccagat
    33481 tcgacaggcg cccttgagag aagtaggcag ctaactctgc tgcgtctgtc ttgactgcat
    33541 cagatgggtc aagatttcct gagatgacaa catggcttcc aggaatgtcc ttagcatgga
    33601 accaaagttc ctccttgcgg gccattttaa aggtcaattc ctcattttga agattgtttc
    33661 gtccgacata gatgatggtt ttgccatcgc ttgctagata ttgttctagt tttttgcgtt
    33721 tctggatttt ctcccgttgt cttctgcgga taaaacctgt ttgaatcaat tcttcacgga
    33781 tttcagcgat ttcttccagt ccagcttggt tgaggacggt ttctacactt tccagataga
    33841 gaatagtggc tttggtttct tcaatcaaat cagtcaagta tttgacagct tctttgagtt
    33901 tctgataccg tttaaaatag cgttgggcat tctggttggg agtcagagcc ttatcaagcc
    33961 caatcatgat aggttggttg gtatagtagt tgtctaggat aacctggtct tggtcgttag
    34021 gcacttggtg gaggaaggtt gtcagcaatt ctcctttttg acgaaattct tcagcgttgt
    34081 ctgtcgccag taattctttt tcctgttttt tgagtttgtg tcggtttttc tgaagttcat
    34141 tttcaacacg acgaatcagt tcactggcct gctgtttgac gcggtcgcgc tcagccttat
    34201 ccttatagta ggtgtccaac aaatcagaaa gatttgcaaa aggctctccc acctgatttg
    34261 caaaaggaac tggactgaag gaagtctcag tcaagcatgg cttggtttcc tgattgaaaa
    34321 aatttcggaa agcggaaagt ttttcactaa ccagtatcct ttccaattca tttgccgtat
    34381 cgcgtcccag accttgaaag aggctttgaa gattttttgc tgttagttct tgggtttgca
    34441 ggatttcaaa gagcttttca tccttgatag taaaaggatt gagagattct gtacttggcg
    34501 gagcgatata ggtcgatcct ggaagtaagg tgcggtagct attttgtgaa aagccgacgt
    34561 gtttgataac ttcgaggatt ttatgactgc ttttatcgac cagtagaata ttactgtgtt
    34621 tccccataat ttcgataatc aaggtagcct ggatatggtc tccaatctcg tttttattgg
    34681 aaactgtcat ttccacaata cggtcatttt ccacttgctc aatcgactca atcagggccc
    34741 cctgcaaata ctttctcaaa accatgataa aggtagaagg ttgggctgga ttttcaaaag
    34801 tcgtttgggt cagctgaatg cgtccaaaaa ctggatgggc agaaaggagc aggcgatggc
    34861 tttggcgatt gctgcggatt tgcaagacca actcttgttc aaaaggctga ttgattttct
    34921 ggatgcgacc attcactaat tcgcttcgca attcctcaac tatgtggtgt aaaaaaaatc
    34981 cgtcaaatga catcgttctc tccttgtgat tgtattccat agtattatat caaaaaggta
    35041 gaataaaatc atggaaatgt ggtataataa agccaagtaa agagaaacga gaagcacatg
    35101 tatattgaaa tggtagatga aactggtcaa gtttcaaaag aaatgttgca acaaacccaa
    35161 gaaattttgg aatttgcagc caaaaaatta ggaaaagaag acaaggagat ggcagtcact
    35221 tttgtgacca atgagcgtag tcataaactt aatctggagt accgtgacac cgaccgtccg
    35281 acagatgtca tcagccttga gtataaacca gaattggaaa ttgcctttga cgaagaggat
    35341 ttgcttgaaa atccagaatt ggcagagatg atgtctgagt ttgatgccta tattggggaa
    35401 ttgttcatct ctatcgataa ggctcatgag caggccgaag aatatggtca cagctttgag
    35461 cgtgagatgg gcttcttggc agtacacggc tttttacata ttaacggcta tgatcactat
    35521 actccggaag aagaagcgga gatgttcggt ttacaagaag aaattttgac agcctatgga
    35581 ctcacaagac aataaacgaa aatggaaaaa tcgtgacctg atatccagtt tagaatttgc
    35641 catcacaggg atttttactg ctatcaagga agaacgcaat atgcgaaaac atgcagtgac
    35701 ggctctagtg gtcatccttg caggttttgg ttttcaggtg tcacgaatcg aatggctctt
    35761 tctcctattg agcattttct tggtggtagc ctttgaaatt atcaattctg ctattgaaaa
    35821 tgtggtggat ttggccagtc actatcactt ttccatgctg gctaaaaatg ccaaggatat
    35881 ggcggctggc gcggtattag tggtttctct ttttgcagcc ttaacaggcg cattgatttt
    35941 tctcccacga atctgggatt tattatttta aacagtaaga ggaaattatg acttttaaat
    36001 caggctttgt agccatttta ggacgtccca atgttgggaa gtcaaccttt ttaaatcacg
    36061 ttatggggca aaagattgcc atcatgagtg acaaggcgca gacaacgcgc aataaaatca
    36121 tgggaattta cacgactgat aaggagcaaa ttgtctttat cgacacacca gggattcaca
    36181 aacctaaaac agctctcgga gatttcatgg ttgagtctgc ctacagtacc cttcgcgaag
    36241 tggacactgt tcttttcatg gtgcctgctg atgaagcgcg tggtaagggg gacgatatga
    36301 ttatcgagcg tctcaaggct gccaaggttc ctgtgatttt ggtggtgaat aaaatcgata
    36361 aggtccatcc agaccagctc ttgtctcaga ttgatgactt ccgtaatcaa atggacttta
    36421 aggaaattgt tccaatctca gcccttcagg gaaataacgt gtctcgtcta gtggatattt
    36481 tgagtgaaaa tctggatgaa ggtttccaat atttcccgtc tgatcaaatc acagaccatc
    36541 cagaacgttt cttggtttca gaaatggttc gcgagaaagt cttgcactta actcgtgaag
    36601 agattccgca ttctgtagca gtagttgttg actctatgaa acgagacgaa gagacagaca
    36661 aggttcacat ccgtgcaacc atcatggtcg agcgcgatag ccaaaaaggg attatcatcg
    36721 gtaaaggtgg cgctatgctt aagaaaatcg gtagcatggc ccgtcgtgat atcgaactca
    36781 tgctaggaga caaggtcttc ctagaaacct gggtcaaggt caagaaaaac tggcgcgata
    36841 aaaagctaga tttggctgac tttggctata atgaaagaga atactaagta gaggtaggct
    36901 catgcctgct tcttgttttt acagaaggag gacttatgcc tgaattacct gaggttgaaa
    36961 ccgtttgtcg tggcttagaa aaattgatta taggaaagaa gatttcgagt atagaaattc
    37021 gctaccccaa gatgattaag acggatttgg aagagtttca aagggaattg cctagtcaga
    37081 ttatcgagtc aatgggacgt cgtggaaaat atttgctttt ttatctgaca gacaaggtct
    37141 tgatttccca tttgcggatg gagggcaagt atttttacta tccagaccaa ggacctgaac
    37201 gcaagcatgc ccatgttttc tttcattttg aagatggtgg cacgcttgtt tatgaggatg
    37261 ttcgcaagtt tggaaccatg gaactcttgg tgcctgacct tttagacgcc tactttattt
    37321 ctaaaaaatt aggtcctgaa ccaagcgaac aagactttga tttacaggtc tttcaatctg
    37381 cccttgccaa gtccaaaaag cctatcaaat cccatctcct agaccagacc ttggtagctg
    37441 gacttggcaa tatctatgtg gatgaggttc tctggcgagc tcaggttcat ccagctagac
    37501 cttcccagac tttgacagca gaagaagcga ctgccattca tgaccagacc attgctgttt
    37561 tgggccaggc tgttgaaaaa ggtggctcca ccattcggac ttataccaat gcctttgggg
    37621 aagatggaag catgcaggac tttcatcagg tctatgataa gactggtcaa gaatgtgtac
    37681 gctgtggtac catcattgag aaaattcaac taggtggacg tggaacccac ttttgtccaa
    37741 actgtcaaag gagggactga tgggaaaaat catcggaatc actgggggaa ttgcctcagg
    37801 taagtcaact gtgacaaatt ttctaagaca gcaaggcttt caagcagtgg atgccgacgc
    37861 agtcgtccac caactacaga aacctggtgg tcgtctgttt gaggctctag tacagcactt
    37921 tgggcaagaa atcattcttg aaaacggaga actcaatcgc cctctcctag ctagtctcat
    37981 cttttcaaat cctgaagagc aaaaatggtc taatcaaatt caaggggaga ttatccgtga
    38041 ggaactggct actttgagag aacagttggc tcagacagaa gagattttct tcatggatat
    38101 tcccctactt tttgagcagg actacagcga ttggtttgct gagacttggt tggtctatgt
    38161 ggaccgagat gcccaagtag aacgcttaat gaaaagggac cagttgtcca aagatgaagc
    38221 tgagtctcgt ctggcagccc agtggccttt agaaaaaaag aaagatttgg ccagccaggt
    38281 tcttgataat aatggcaatc agaaccagct tcttaatcaa gtgcatatcc ttcttgaggg
    38341 aggtaggcaa gatgacagag attaactgga aggataatct gcgtattgcc tggtttggta
    38401 attttctgac aggagccagt atttctttgg ttgtaccttt tatgcccatc ttcgtggaaa
    38461 atctaggtgt agggagtcag caagtcgctt tttatgcagg cttagcaatt tctgtctctg
    38521 ctatttccgc ggcgctcttt tctcctattt ggggtattct tgctgacaaa tacggccgaa
    38581 aacccatgat gattcgggca ggtcttgcta tgactatcac tatgggaggc ttggcctttg
    38641 tcccaaatat ctattggtta atctttcttc gtttactaaa cggtgtattt gcaggttttg
    38701 ttcctaatgc aacggcactg atagccagtc aggttccaaa ggagaaatca ggctctgcct
    38761 taggtacttt gtctacaggc gtagttgcag gtactctaac tggtcccttt attggtggct
    38821 ttattgcaga attatttggc attcgtacag ttttcttact ggttggtagt tttctatttt
    38881 tagctgctat tttgactatt tgctttatca aggaagattt tcaaccagta gccaaggaaa
    38941 aggctattcc aacaaaggaa ttatttacct cggttaaata tccctatctt ttgctcaatc
    39001 tctttttaac cagttttgtc atccaatttt cagctcaatc gatcggccct attttggctc
    39061 tttatgtacg cgacttaggg cagacagaga atcttctttt tgtctctggt ttgattgtgt
    39121 ccagtatggg cttttccagt atgatgagtg caggagtcat gggcaagcta ggtgacaagg
    39181 tgggcaatca tcgtctcttg gttgtcgccc agttttattc agtcatcatc tatctcctct
    39241 gtgccaatgc ctctagcccc cttcaactag gactctatcg tttcctcttt ggcttgggaa
    39301 ccggtgcctt gattcccggg gttaatgccc tactcagcaa aatgactccc aaagccggca
    39361 tttcgagggt ctttgccttt aatcaggtat tcttttatct gggaggtgtt gttggtccca
    39421 tggcaggttc tgcagtagca ggtcaatttg gctaccatgc tgtcttttat gcgacaagcc
    39481 tttgtgttgc ctttagttgt ctctttaacc tgattcaatt tcgaacatta ttaaaagtaa
    39541 aggaaatcta gtgcgagtaa aaattaatct caaatgctcc tcttgtgaca gtatcaatta
    39601 cctaaccagt aaaaattcaa aaacccatcc agacaagatt gaggttttaa agtattgtcc
    39661 caaggaaaga aaagtaaccc tacatcttga atctaagtag attttatggt aaaataatag
    39721 ggattttaag gagtttgata tgtataacct attattaacc attttattag tattatctgt
    39781 tgtgattgtg attgcaattt tcatgcaacc aaccaaaaac caatccagca atgtatttga
    39841 tgccagttca ggtgatttgt ttgaacgcag taaagctcgc ggttttgaag ctgtaatgca
    39901 gcgtttgaca gggattttag tctttttctg gctagccatt gccttagcat tgacggtatt
    39961 atcaagtaga taagaaaata atgggcagga ctaggtcttt gcctcttttt atttttaaag
    40021 gatgtttgag aaggttttac agtaaaagaa aattaaaaaa tctagaaaga aaatatgaaa
    40081 gatagaataa aagaatattt acaagacaag ggaaaggtga ctgttaatga tttggctcag
    40141 gctttgggaa aagacagttc caaggatttt cgtgagttga ttaaaacctt gtccttaatg
    40201 gaaagaaagc accagattcg ctttgaagaa gatggtagtc tgacattaga aattaagaaa
    40261 aaacatgaga ttaccctcaa ggggattttt catgcccata aaaatggctt tggctttgtt
    40321 agtctggaag gcgaggagga cgaccttttt gtagggaaaa atgatgtcaa ctatgctatt
    40381 gatggtgata ccgtcgaggt agtgattaag aaagtcgctg accgcaataa gggaacagca
    40441 gcagaagcca aaattattga tatcctagaa cacagtttga caacagttgt cgggcaaatc
    40501 gttctggatc aggaaaagcc taagtatgct ggctatattc gttcaaaaaa tcataaaatc
    40561 agtcaaccga tttatgttaa gaaaccagcc ctaaaattag aaggaacaga agttctcaaa
    40621 gtctttatcg ataaataccc aagcaagaaa catgatttct ttgtcgctag tgtactcgat
    40681 gtagtgggac actcaacgga tgtcggaatt gatgttcttg aggtcttgga atcaatggac
    40741 attgtatctg agtttccaga agctgttgtc aaggaagcag aaagtgtgcc tgatgctccg
    40801 tctcaaaagg atatggaagg tcgtctggat ctaagagatg aaattacctt taccattgac
    40861 ggtgcggatg ccaaggactt agacgatgca gtgcatatca aggctctgaa aaatggcaat
    40921 ctggagcttg gggttcacat cgcagatgtt tcctattatg tgaccgaggg gtctgccctt
    40981 gacaaggaag cccttaaccg tgcgacttct gtttacgtga cagaccgagt ggtgccaatg
    41041 cttccagaac gactatcaaa tggcatctgc tctctcaatc cccaagttga ccgcctgacc
    41101 cagtctgcta ttatggagat tgataaacat ggtcgtgtgg tcaactatac cattacacaa
    41161 acagttatca agaccagttt tcgtatgacc tatagcgatg tcaatgatat cctagctggc
    41221 gatgaagaaa agagaaaaga atatcataaa attgtaccaa gtatcgaact catggccaag
    41281 cttcatgaaa ctttagaaaa catgcgtgtg aaacgtggag ctctcaattt tgataccaat
    41341 gaagcgaaga ttttagtgga taaacaaggt aagcctgttg atatcgttct tcggcagcgt
    41401 ggcattgccg agcggatgat tgagtctttt atgttgatgg ctaatgaaac agttgccgaa
    41461 catttcagca agttggattt gccttttatc tatcgaattc acgaggagcc taaggctgaa
    41521 aaggttcaga agtttattga ttatgcttcg agttttggct tgcgcattta tgggactgcc
    41581 agtgagatta gtcaggaggc acttcaagac atcatgcgtg ctgttgaggg agaaccttat
    41641 gtagatgtat tgtccatgat gcttcttcgc tctatgcagc aggctcgtta ttcggagcac
    41701 aatcacggcc actatggact agctgctgac tattatactc actttaccag tccaattcgt
    41761 cgttatccag accttcttgt tcaccgtatg attcgggatt acggctgttc taaggaaata
    41821 gcagagcatt ttgaacaagt gattccagag attgcgaccc agtcttccaa ccgtgaacgt
    41881 cgtgccatag aagctgagcg tgaagtcgaa gccatgaaaa aggctgagta tatggaagaa
    41941 tacgtgggtg aagagtatga tgcagttgta tcaagtattg tcaaattcgg tctctttgtc
    42001 gaattgccaa acacagttga aggcttgatt cacatcacta atctacctga attttatcat
    42061 ttcaatgagc gtgatttgac tcttcgtgga gaaaaatcag gtatcacttt ccgagtgggt
    42121 cagcagatcc gtatccgtgt tgaaagagcg gataaaatga ctggagagat tgatttttca
    42181 ttcgtaccta gtgagtttga tgtgattgaa aaaggcttga aacagtctag tcgtagtggc
    42241 agagggcgtg gttcaaatcg tcgttcggat aagaaggaag acaagagaaa atcaggacgc
    42301 tcaaatgata agcgtaagca ttcacaaaaa gacaagaaga aaaaaggaaa gaaacctttt
    42361 tacaaggaag tagctaagaa aggagccaag catggcaaag ggcgagggaa aggtcgtcgc
    42421 acaaaataaa aaggcacgcc acgactatac aatcgtagat acgctagagg cagggatggt
    42481 cctgactgga actgaaatca agagtgtacg agctgctcga attaatctca aggatggctt
    42541 tgctcaagtg aaaaatggag aagtttggct gagcaatgtt catatcgcgc cttacgaaga
    42601 gggcaatatc tggaaccagg aaccagaacg tcgtcgtaaa ctcctgctcc ataaaaagca
    42661 aattcaaaaa ttggaacaag agaccaaagg gacaggaatg accttagttc cccttaaggt
    42721 ctatataaaa gatggctacg ctaagcttct tttaggactt gccaaaggga agcatgacta
    42781 tgacaaacgg gagtctatca aacgtcgtga gcaaaatcga gatatcgcgc gtgtgatgaa
    42841 agctgttaat cagcgataaa aagaggaatt gaaaatggaa aaattagttg cctataaacg
    42901 catgcctttg tggaataaac aaacaatgcc tgaagctgtt cagcaaaagc acaatacaaa
    42961 agttgggact tgggggaaaa ttactgtctt gaagggagct ctcaagttta ttgaattgac
    43021 agaagaaggg gaagttctag ctgaacacct ctttgaagca ggggcagaca atccaatggc
    43081 ccaacctcaa gcctggcacc gagtggaagc tgccacagat gatgtggaat ggtacttgga
    43141 attttattgt aaacctgagg attattttgc taaaaaatac aataccaatc ctgttcattc
    43201 agaggtccta gaggccatgc agacagtgaa acaagggaaa gctttggatt tgggttgtgg
    43261 tcaggggcgt aattctcttt ttctagccca gcaagatttt gatgtgacgg ctgtagatca
    43321 aaatggacta gctcttgaaa tcttgcaaag cattgtggag caggaagatt tggacatgcc
    43381 tgttggcctt tacgatatca attcagctag cattgaacaa gaatatgatt ttatcgtttc
    43441 aacagttgtt ctcatgtttc tacaagcgga ccgcattcca gctattattc aaaatatgca
    43501 ggagaaaacc agtgttggcg gttacaacct tatcgtttgt gccatggaca cggaggatta
    43561 tccttgctcg gttaacttcc cattcacctt taaagaagga gaactggcag actattacaa
    43621 ggattgggaa ttggttaagt acaatgaaaa tccaggccat ttgcaccgtc gcgatgagaa
    43681 tggcaatcgt attcaactac gctttgcgac cttactagct aagaaaatca agtaaacaca
    43741 catgaagatt aggaattttc ctgatctttt ttctttttta cgaatgatat agaaaaggag
    43801 ggaattcatg tttgttgcga gagatgctag gggagaattg gtaaatgtgt tagaggataa
    43861 acttgagaag caagcataca cctgcccagc ttgtggaggc cagctccatt tgcgtcaagg
    43921 accaagtgta cggacgcatt ttgcccataa atccttaaaa gactgtgatt ttttctttga
    43981 aaatgaaagt ccagaacacc tggccaataa ggaatccctc tatcactggt tgaaaaaaga
    44041 gacaaaggtt caattagagt acccgctttc agaacttaaa cagattgcgg atgtatttgt
    44101 aaatggcaat ctagctctag aagttcagtg tagtcccttg cctcagaaag tccttaaaga
    44161 gcgaagtgag ggctatcgta gtcagggtta ccaagtactg tggttgctgg gtcaaaaact
    44221 gtggctcaag gagcgtttga ctcgtctaca gcaaggtttt ctttatttca gtcaaaacat
    44281 gggcttttat gtttgggaat tagacaagga aaaacaagtt ttaagactca aatacctgat
    44341 ttaccaggat ctccgcggta aactccatta tcaaatcaag gaattttcct atggtcaagg
    44401 tagtttattg gaaatattgc gtcttcccta taagagacaa aaaatatctc attttacagt
    44461 ttctgaggac aaggacatct gtcgctatat ccggcaacaa ctttattatc aaaatctctt
    44521 ttggatgaaa gaacaagcag aagcctatca aaagggagaa aatatcctga cttatggact
    44581 gaaagaatgg tatccacaaa ttcgaccaat agtgggcaaa tttttccaga ttgaacaaga
    44641 cttgactagc tattatcagc acttttatac ctattaccaa aaaaatcctc aaaatgattg
    44701 gcaaaagctt tatccaccag ccttttatca gcaatatttc ttgaaaaata tggtagaata
    44761 gaaaggatgg aggaatctaa tggtattaca aagaaatgaa ataaatgaaa aagatacatg
    44821 ggatctatca acgatctacc caactgacca ggcttgggaa gaagccttaa aagatttaac
    44881 agaacaattg gagacagtag cccagtatga aggccatctc ttggatagtg cggataacct
    44941 actagaaatc actgaatttt ctcttgaaat ggaacgccag atagagaagc tttacgttta
    45001 tgctcatatg aagaatgacc aggatacacg tgaagctaag tatcaagagt actatgccaa
    45061 ggccatgaca ctctacagcc agttagacca agccttttca ttctatgagc ctgaatttat
    45121 ggagattagc gaaaagcagt atgctgactt tttagaagct caaccaaagc tgcaggttta
    45181 tcaacactat tttgacaagc tcttgcaagg caaggatcac gttctttcac aacgtgaaga
    45241 agaattattg gctggagctg gagaaatctt tggttcagca agtgaaacct tcgctatctt
    45301 ggacaatgcg gatattgtgt tcccttatgt cctagacgat gatggtaaag aagttcagct
    45361 atctcatggg acttacacac gtttgatgga gtctaaaaaa cgtgaggttc gccgtggtgc
    45421 ctatcaagct ctttatgcta cttacgaaca attccaacac acctatgcca aaaccttgca
    45481 aaccaatgtt aaggtgcaaa attaccgtgc taaagttcgt aactacaaga gtgctcgtca
    45541 tgcagccctc gcagcgaatt ttgttccaga aagtgtttat gacaatttgg tagcagcagt
    45601 tcgcaagcat ttgccactct tacatcgcta tcttgagctt cgttcaaaaa tcttggggat
    45661 ttcagatctc aagatgtacg atgtctacac accgctttca tctgttgaat acagttttac
    45721 ctaccaagaa gccttgaaaa aagcagaaga tgctttggca gtcttgggtg aggattactt
    45781 gagccgtgtt aaacgtgcct tcagcgagcg ttggattgat gtttacgaaa atcaaggcaa
    45841 gcgttcaggt gcctactctg gtggttctta cgataccaat gcctttatgc ttctcaactg
    45901 gcaggacaat ctggacaatc tctttactct tgttcatgaa acaggtcaca gtatgcattc
    45961 aagctatact cgtgaaactc agccttatgt ttacggggat tactctatct ttttggctga
    46021 gattgcctca actaccaatg aaaatatctt gacggagaaa ttattggaag aagtggaaga
    46081 cgacgcaaca cgctttgcta ttctcaataa cttcctagat ggtttccgtg gaacagtttt
    46141 ccgccaaact caatttgctg agtttgaaca cgccattcac caagcagatc aaaatgggga
    46201 ggtcttgaca agcgatttcc taaataaact ctacgcagac ttgaaccaag agtattatgg
    46261 tttgagtaag gaagacaatc ctgaaatcca atacgagtgg gctcgcattc cacacttcta
    46321 ctataactac tatgtatatc aatattcaac tggctttgcg gccgcctcag ccttggctga
    46381 aaaaattgtc catggtagtc aagaagaccg tgaccgctat atcgactacc tcaaggcagg
    46441 taagtcggac tatccactta atgtcatgag aaaagctggt gttgatatgg agaaggaaga
    46501 ctacctcaac gatgcctttg cagtctttga acgccgttta aatgagtttg aagcccttgt
    46561 tgaaaaatta ggattggcat aaaatggttg aatcgtatag taagaatgct aaccataaca
    46621 tgcgtcgtcc tgtcgtcaaa gaagaaattg tagacttgat gcgtcagcgt caaaagcagg
    46681 tcacaggttt cttgaaagaa ttggaagact ttgcccgcaa ggaaaatatt cctattattc
    46741 cccatgaaac ggttgcttat ttccgttttc ttatggaaac catgcagcct aaaaatattc
    46801 tggaaattgg gacggctatc ggtttttcag ctctcttgat ggctgaacat gcgccaaatg
    46861 ctaagattac aactattgat cgtaatccag aaatgattgg ttttgccaag gaaaattttg
    46921 cccagtttga cagtcgcaag caaatcactc tcctagaggg agatgcggtg gatgtcttat
    46981 ctacactgac agagtcttat gatttcgtat ttatggattc tgccaagtct aaatacatcg
    47041 tctttctgcc agaaatcctc aaacatttgg aagttggtgg tgtggttgtc ttggatgata
    47101 tttttcaagg tggtgatgtt gccaaggata ttatggaagt ccgtcgtggt cagcgaacca
    47161 tttatcgagg ccttcaaaaa ttatttgatg caaccttaga caatccagaa ctcaccgcaa
    47221 cattagtgcc tttaggagat ggtattctca tgcttcgtaa aaatgtagca gatgttcaac
    47281 tgtctgaaag cgaatgattt tcagaaaaat ttaagaaaaa atagtaaaat agatagagta
    47341 acacttatct caaaggagta gacatgaaga aaaaattatt ggcaggtgcc atcacactat
    47401 tatcagtagc aactttagca gcttgttcga aagggtcaga aggagcagac cttatcagca
    47461 tgaaagggga tgtcatcaca gaacatcaat tttatgagca agtgaaaaac aacccttcag
    47521 cccaacaagt cttgttaaat atgaccatcc aaaaagtttt tgaaaaacaa tatggctcag
    47581 agcttgatga taaagaggtt gatgatacta ttgccgaaga aaaaaaacaa tatggcgaaa
    47641 actaccaacg tgtcttgtca caagcaggta tgactcttga aacacgtaaa gctcaaattc
    47701 gtacaagtaa attagttgag ttggcagtta agaaggtagc agaagctgaa ttgacagatg
    47761 aagcctataa gaaagccttt gatgagtaca ctccagatgt aacggctcaa atcatccgtc
    47821 ttaataatga agataaggcc aaagaagttc tcgaaaaagc caaggcagaa ggtgctgatt
    47881 ttgctcaatt agccaaagat aattcaactg atgaaaaaac aaaagaaaat ggtggagaaa
    47941 ttacctttga ttctgcttca acagaagtac ctgagcaagt caaaaaagcc gctttcgctt
    48001 tagatgtgga tggtgtttct gatgtgatta cagcaactgg cacacaagcc tacagtagcc
    48061 aatattacat tgtaaaactc actaagaaaa cagaaaaatc atctaatatt gatgactaca
    48121 aagaaaaatt aaaaactgtt atcttgactc aaaaacaaaa tgattcaaca tttgttcaaa
    48181 gcattatcgg aaaagaattg caagcagcca atatcaaggt taaggaccaa gccttccaaa
    48241 atatctttac ccaatatatc ggtggtggag attcaagctc aagcagtagt acatcaaacg
    48301 aatagtccaa atcaatgagt cagggaaaaa actctacttc aggaaaaaat gaagcaaaca
    48361 ttcccacaat aaaacgcgta gtacaaggtt tgtactgacc cccaaaagtt agacaaataa
    48421 tttatccgaa ggatttagtt ctgtattgca cagggctaag tccttttagt tttaccttaa
    48481 ttctcttgtt gttgtaataa tcaatatagt atataatggc ttgttccaat tgattaagtg
    48541 atttaaatgt tttctcatag ccataaaaca tttcggattt taaaatacca aagaaagatt
    48601 ccatcctacc gttgtcttgg ctgtttccct tgcgtgacat agatgcttga attcccttac
    48661 tctctaggaa ccgatgataa gaatcgtgtt ggtattgcca gtcttggtca ctatggagaa
    48721 tcgtattctc gtagtgcttc tctttgaatg cctgttccaa cattaacgat caatcaattt
    48781 aatcatgtac ctaatattag aattgtttat ctcaaattta tttgaaagct tctctaagct
    48841 atatccttgt tttctaagtt catagatctg aactttatca tcataagtta atttcataat
    48901 aaaaacactc caaaagttag attttttctg tctaactttt ggggtgcagt tcatttaaca
    48961 cctgataata tgcgtttttt ttattttaaa gactttttga ccagcctcat tttttaactt
    49021 gatactcagt gaaaagcaaa gattaaacta ggaagctagc tgtaggctgc tcaaagaaca
    49081 gctttgaggt tgcagataaa acttgtgagg taaccaacat atataatgtg aagctgacgt
    49141 ggtttgaata gattttagaa gggtatgagt ctggaagttt taatggataa tgcaagattc
    49201 catagaatgg gtaagctaga gttcttatgt gaagagtttg ggcataaact tttacctttt
    49261 cctccctact catcttagta tagaaaagtg aatctaaaat agtacataac tgcttctaaa
    49321 acattcttat aaattgattt aaattctcaa atcatattat tcagttctta tttcattttg
    49381 ctctacaatc ctgttgagaa gacacgtgtt catatcaaaa aaggtattgg caagttgcaa
    49441 taccttttta cgaggctctt ttatcttatt tttgtttcaa ctgactatat ctcctatggt
    49501 tctagttcag aaggctaggc tataattatg attgataaga agtatcattc caagtattga
    49561 gagtgaatgt ttcaaaatca tgggtttcta taatggtcag gctggcattt gctagaccgc
    49621 catctttacg aagaagtggt tctttatagc ctaggagagt acgaagactg gcagtaagat
    49681 tggcgccgtg tccgacaatt agaatacgtt cagctggact atcttttaat gatttgataa
    49741 attggatggt ccgttgagtt gtactataga gggattcggc tccgaacatt cgagtgtcaa
    49801 attgagcaag atttgaacga aaagcctgga tttgttgcgg gtaaatagct tccaaggttg
    49861 caattttcaa accttctaac ttcccaagtt gccattcacg gagattagga acgatttcta
    49921 aagaacaggg ggtatagagt tgactttgga taatctcagc agatttgacc gctcgaggta
    49981 aatcacttga ataaatctga tcaaaaggaa tttccttgag atactgacca agtcgtttta
    50041 gggtttcaat ggattcagga agaagaggag aatcaccact agcaccttga aaacgacctt
    50101 cttggttcca gagggtacga ccgtggcgga caaagtagag tttcattact tgatgtcctc
    50161 caaaatatct acaaagtctg cctttacaaa gctagccaag tcttgtggcg cgacgataat
    50221 gctgtgtccg acttcgcctg cagagacaat catttgatcc aaatctagag caattttatc
    50281 gataaaaatg ggataattgt gtttctgacg aattccgaca ggattattgg ctccatgaat
    50341 gtaaccagtt gttttttcta agtccttttg tggaatcatg ctcacttttt tattgccaga
    50401 aattttagct agtttctttt cagacaagtg ctgagtgata gggacaattc cgataatcgg
    50461 tccggtcttg tctcccaaaa gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg
    50521 aggaagctct ccttctaggg cattgatttg aatcccctga tgagggatag ctgctttaga
    50581 taggatttgt tccgccaatg tttttttgat tttaactttt tttgccatta tttatattta
    50641 tcctccaatt gactcatcca aataccaagc cagattccca gcgcaaagaa gaaggcgatg
    50701 atgacataac cgacaagtga aagtcctgtg tattggatac tttcagcgtt tcctgcattt
    50761 ggaattaaga tcaaaagggt acttgatagg acgataccga tgatgaaatg atagacacgt
    50821 gagtggtagt tgtttaaggc ataatccatc aattttgaaa aaacgatgag agttgcacct
    50881 gcaccaattc caatcggaaa gaaggttccc aagaaatcaa aagttttaaa accagtcaac
    50941 ataggagcat agagtcccaa aatcaaaagt aaatttgatg ggctgaggcc aggaaccaag
    51001 acgccaaggg ccaatagtgc gcctgctagg acgaagttaa gaaagctggc gcttaaggtt
    51061 ccaacgacaa aatttaaggc atagagtcct aatccagaaa tgataaaggt tgtccataac
    51121 caagctaaat caatcttgtc tcggtcagat tctcgagttg attctttgag gaggctagga
    51181 actgtaccga taatagctcc cgcaaagctc cataatacaa aaacctgata attttcaagc
    51241 aggtattcaa tcgggtagga aaataagccg attcccagaa gcataccgat ggcaactgga
    51301 ataaagtaca aaacattttc tttaaagtct ttaaagggat gggccagaaa gccaatcatt
    51361 cgttcataga ttcctaagat tgctgctaga acccctccgg aaattcccgg taggataaat
    51421 ccaagagcaa ttacaatccc tttaataacg cgtgctaacc atgagagcat atatttcctc
    51481 caactatttc tatttcaaaa aatccttact atattgtatc acaatcagac acaaaaagaa
    51541 aaagcaaatg ataaacaaat gcttttaagg ttttaaaaaa agttttcgaa aggtttcttc
    51601 tttatttttt aagggagaga taacgttgat atctaaatcg tggtcaaagc cggcaatttt
    51661 tcctttagat gtgtattggt gaatatcata atctaaatca gttttaggac tgctctccaa
    51721 aaatcctgag tctgagccgt aggacggaat ccaaacagag gtaaacttgc ctgtatcaat
    51781 actgtgttct tccatgaagt agacaccaac gtagatgccg atgtttttag cacctagtga
    51841 tgctagtttt gctcgaaagt tttcgacacc ttcgttcata ttagacatgg ttttgtcttc
    51901 cacgtcaagc caatagtaac tagggctgta aggagaggca gcattgtaga aaacttcggc
    51961 agccttttcc atttcttgga cactttttcc agctacataa gcgtagacag caactgggac
    52021 attccgcttt tgaagttcag tgatatgact cttataggcc ttgtctattc cattgataaa
    52081 tgaagcatca ttttcttttg tcgtttgagc accactgtga acacgaacaa tagcacctga
    52141 aatattttgt gagagggcat cgtagttgat ttcttcagga cgctgccagc cagagaggtc
    52201 aataatcggt ttgtctaagt gtttcaaagc ctgtgcttca atctgtgcta tattggattt
    52261 tgttttaaac gattggttgt cattaagtgg gcgattgatg attaaaatga acatcataat
    52321 ccccaaaaaa ctaaataaaa taagtggatg aatttgtttt ctcatatctt ataattctac
    52381 cctaaaaatc aaaaaaaatc aaaaaaatgg gttaaggaag agactttaga gcattttttc
    52441 attcaagagt gcggaatgat ttgaaatatg gtataataaa agggaatttc tacagaaaag
    52501 agaagattat gtcaaatttt gccattattt tagcagcggg taaagggact cgcatgaaat
    52561 ctgatttgcc aaaagttttg cacaaggttg cgggtatttc tatgttggaa catgttttcc
    52621 gtagtgtggg agctatccaa cctgaaaaga cagtaacagt tgtaggacac aaggcagaat
    52681 tggttgagga ggtcttggct ggacagacag aatttgtgac tcaatctgaa cagttgggaa
    52741 ctggtcatgc agttatgatg acagaaccta tcttagaagg tttgtcagga cacaccttgg
    52801 tcattgcagg agatactcct ttaatcactg gtgaaagctt gaaaaacttg attgatttcc
    52861 atatcaatca taaaaatgtg gccactatct tgactgctga aacggataat ccttttggct
    52921 atggacgaat tgttcgtaat gacaatgctg aggttcttcg tattgttgag cagaaggatg
    52981 ctacagattt tgaaaagcaa atcaaggaaa tcaacactgg aacatacgtc tttgacaacg
    53041 agcgtttgtt tgaggctttg aaaaatatca ataccaataa cgctcaaggc gaatactata
    53101 ttacagacgt cattggtatt ttccgtgaaa ctggtgaaaa agttggcgct tatactttga
    53161 aagattttga tgaaagtctt ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag
    53221 ttatgcgtcg tcgcatcaat cataaacata tggtcaacgg tgttagcttt gtcaatccag
    53281 aagcaactta tatcgatatt gatgttgaga ttgctccgga agttcaaatc gaagccaatg
    53341 ttaccttgaa agggcaaacg aaaattggtg ctgagactgt tttgacaaac ggtacttatg
    53401 tagtggacag cactatcgga gcaggagcgg tcattaccaa ttctatgatt gaggaaagta
    53461 gtgttgcaga cggtgtgaca gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg
    53521 gtgcccaagt tcatattggt aactttgttg aggtgaaagg atcttcaatc ggtgagaata
    53581 ccaaggctgg tcatttgact tatatcggaa actgtgaagt gggaagcaac gttaatttcg
    53641 gtgctggaac tattacagtc aattatgacg gcaaaaacaa atacaagaca gtcattggag
    53701 acaatgtctt tgttggttca aattcaacca ttattgcacc agtagaactt ggtgacaatt
    53761 ccctcgttgg tgctggttca actattacta aagacgtgcc agcagatgct attgctattg
    53821 gtcgcggtcg tcagatcaat aaagacgaat atgcaacacg tcttcctcat catcctaaga
    53881 accagtagga gcctatcatg gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc
    53941 aaggaccaat atttaaactg gtccaagatc aggttgaatt accagaaggc aagggaactg
    54001 cccaacggga tttgattttc cacaatgggg ctgtctgtgt tttagcagta acggatgaac
    54061 aaaaactgat cttggtcaag cagtaccgca aagctatcga ggctgtctct tacgaaattc
    54121 cagccggaaa attggaagta ggagaaaaca cagcccctgt ggcagctgcc cttcgtgaat
    54181 tagaggaaga aacagcctat acagggaaat tagaactctt gtacgatttt tattcagcta
    54241 ttggcttttg taatgagaag ttaaaactat atttagcaag cgatttgaca aaagtggaaa
    54301 atccgcgtcc gcaggatgag gatgaaacct tggaagtcct tgaagtgagc ttagaagaag
    54361 cgaaagaatt aatccaatca ggtcatattt gtgatgccaa gacaattatg gctgttcagt
    54421 attgggagtt gcagaaaaaa tagaggaggt cagtatgggt aaatctttat taacggatga
    54481 aatgattgaa agagctaata gaggcgaaaa aatttcaggt cctcctttgc tagatgataa
    54541 tgaggagact aagattttac caacctcttc ttcccgtttt ggttatgcca atcctaagaa
    54601 tcatggtttt agccaggaaa ccttgaagat tcaggtcgaa ccatctattc ataaaagccg
    54661 tcgcattgaa aataccaaga gaaatgtctt caattctaag ttgaataaaa tcttattcgc
    54721 ggtcatcttt ctcttgattt tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa
    54781 ttgaaatgaa aataggaatt attgctgcta tgccagaaga actggcttat ctggtccagc
    54841 atttatataa tgtccaggag caagttgttt tggggaatac ctatcataca ggaaccattg
    54901 cttctcatga agtcgttctt gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg
    54961 tggcgatttt ggctgatcat ttccaggtgg atgcccttat taatacgggt tcagctgggg
    55021 cagtagcaga aggtatcgct gttggggatg tcgtgattgc tgacaaatta gcctatcatg
    55081 acgtggatgt cacagctttt ggctatgctt atggacaaat ggcgcaacaa ccgctttatt
    55141 tcgaatcaga caaaaccttt gttgctcaaa tccaagagag tttatctcaa ttggaccaaa
    55201 actggcatct tggtttgatt gctacaggag atagttttgt tgcaggaaat gacaagatag
    55261 aagcgattaa gtcccatttc ccagaagttt tagccgtgga gatggagggg gcagctattg
    55321 ctcaagcagc gcataccctc aatctcccag tcttagtcat ccgagctatg agtgacaatg
    55381 ccaaccatga agcaaacatc ttttttgatg agtttattat cgaagctgga cgtcgctctg
    55441 cccaagtctt gttggccttt ttgaaggctt tagattaagc ggaaatttga cagtttttct
    55501 agcttatgat aagatttaag taaagaaaag ctagaaaacg tttcagagga tattatgagt
    55561 attgaaatga ccgtcagtga gattgcagag gtcttaggat tatctcgcca agcaatcaat
    55621 aaccgtgtca aagaattacc agaagaagac acagataaaa atgacaaagg ggtaacagtt
    55681 gttaccagaa gtggcttgat taagctagaa gaaatctata aaaaaacgat ttttgaagat
    55741 gaacctgtca gtgaagatgt caaacaacgt gaactgatgg agattctagt ggatgagaag
    55801 aatgcagaaa ttcttcgtct ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa
    55861 aaagacgagc agatgcgtat caaagaccgt cagattgctg agaaagacaa acaattagat
    55921 cagcaacaac aattgaccct tcaagccatg aaggatcaag aaaatcttaa gctagagctg
    55981 gaccaagcaa aagaagaagt ccaatccact aaaaaaggct tttttgctcg tttatttgga
    56041 ggataatcaa ggagctgttt aggttaaatg ctaacctgat ggcttctttt gtttgtgaat
    56101 agtatagttg attagaacag agacagtaga ggagaggtac agaatggaac gattagaaga
    56161 ttacattgct tttgatttag aatttaatca gcacgaagga caaacacact tgattcaagt
    56221 atcggcagtg cgttttagag atggtcggga aatcgatgcc tatgattcct atgttcatac
    56281 cagcgtccct ctaaaaagct ttatcaatgg tttgaccggg attacagctg agaccttaaa
    56341 agatgctcct ccagttgaga aagtcttaga agaattccaa gagtttgtgg gttctttgct
    56401 gatgataggc tacaatgctg ctaaaagtga tttacctatt ttagcagagc atggtttaga
    56461 ctatagccaa cagtacaagg tggatttgta tgatgaagct tttgaacgtc ggagttcaga
    56521 tttacatggt attgccaatc tcaaattgca aactgttgcc tcatttcttg gatttcaagg
    56581 tcagtctcat aatagtttag aggatgctcg gatgacggcg cgtgtttacg aatccttctt
    56641 agagtcggat caagctaggg aattgttaga gacagaaagt agcttatcaa acaatccttt
    56701 tggtggcttg gacttgtctc aattatttga ctaggagtgc ctatgaaacc tgaaaaacct
    56761 aaaaaattgg gtcttaaaca gatttacctc aatcttgata aaatcctctt tctatttttc
    56821 ttgattttta tgatagtgga gtatttgtgg gtaccattca attcatggtt ggctagcttc
    56881 ttattagatc agacaggtta tctttttatt tcctataaca atgtcttagc catccttact
    56941 cattctccat tgattagtct agctttttta gccttgattg taattaactt tctggttgct
    57001 tattttcaaa taggactcct ctttattggt gctcgtcatc tcctctataa tgaaaagcga
    57061 aggctaattg agtatatccg caaggttttc catgaaagtt ttgaatttat gaaaaagcta
    57121 actggcgcta aagccttgtt tatctttttc tatatagcta tgctgtttcc ttttatacgg
    57181 aaaatgctga agatttatta tcttaataaa atcgtcattc cagagtttat ccaagcttat
    57241 ttagaagata aatattggat gtggtggctg agcatcctac ttctatctct tatctttctc
    57301 tatgtctctg tcagattgat gtttgccctt ccgaagattg tatatgatca gctgactgtt
    57361 cgagaagcag tgatgtttag cttggagaaa accaagaaga gagttacttt ttatgcttgg
    57421 aatttatttt acatcttgct caaagcacat ttattatttt atcttccttt gattccttta
    57481 ttattggctc aaactttggt agatgatatc actcagagag agtctctgat tcttggtatt
    57541 ttgaattttg tcgtgattaa aaatctctat tatatggctc tgacttattt tttggttaaa
    57601 tttgtttcat ttttgacagg aaaggagctg gatatgcttc ctaggagaga aaaagatcac
    57661 atcgtgcgat ggggtgtcat gacttgtgcc agttttttct ttgccttaga aggttatatt
    57721 tatctggagg ctcccatggt tcatctacct caacttattt ctcaccgagg ggtttccaat
    57781 gcaaatggga ttcaaaatac agtagagtcc ttggaaacta cagcacaact caaaccagac
    57841 ttggtggaga cggacgtgca ggaaacaaaa gatgggcagt ttgtcatgat gcatgatgct
    57901 aacttgaaaa atctagcagg tatcaataaa agtcctcaag acttaaactt ggaggagctt
    57961 aaagggattg atatttttga aaatggctac cagactaaaa tttcaagctt tgaagattat
    58021 ctcagtcgag ccaacgaact tggtcaaaaa ttactaattg aaattaaaac cagtaaaaaa
    58081 gatagtccag acatgatgaa ccgcttttta gcccgttatg ctgcaaagct caagatttat
    58141 ggacatcaaa tccagtcttt agactaccat gttgtcgaaa aagtaagaca gtatgatgcc
    58201 gaactgccag tttatttcat catgccctac aattctgtct ttcctaaaac aagagcgaca
    58261 ggatatacta tggagtactc aaccttggat gaatattttg taagcaaact atggacaacg
    58321 gatcagaaac tttatgtctg gactgtcaat gattcagaag ctatcagcaa atctcttcac
    58381 ttaggagtag atggagtgat tacagatgat ttggaaaaag ttcagcggga aatagaagta
    58441 gcccaagaag atccagaata tacggatttg ctcttgaaaa aagcattgga attctttgaa
    58501 ttttagtaat aaaaaagagg aacggttgtt cctcccatga taggtaagta ttcttgtgaa
    58561 tgcttgcttt tttgtggttg caatccgttt acgagaattg tttgtattgt tcttgtttca
    58621 atttacttta tagtgctttg aagttggaat gctacactat aacttct
//
LOCUS       DAVKBK010000008        50200 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVKBK010000008 DAVKBK010000000
VERSION     DAVKBK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50200
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.008"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            49..1296
                     /locus_tag="VWX69_000519"
     CDS             49..1296
                     /locus_tag="VWX69_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU9191914.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            1374..2663
                     /locus_tag="VWX69_000520"
     CDS             1374..2663
                     /locus_tag="VWX69_000520"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU9191915.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETISMAAYFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            2918..3232
                     /locus_tag="VWX69_000521"
     CDS             2918..3232
                     /locus_tag="VWX69_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191916.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     FQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            3242..3448
                     /locus_tag="VWX69_000522"
     CDS             3242..3448
                     /locus_tag="VWX69_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191917.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            3448..3645
                     /locus_tag="VWX69_000523"
     CDS             3448..3645
                     /locus_tag="VWX69_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191918.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNLYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            3648..4370
                     /locus_tag="VWX69_000524"
     CDS             3648..4370
                     /locus_tag="VWX69_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU9191919.1"
                     /translation="MKKKRRLLFLMSIVLGMFVGMFKARVESHEIILDVKALMPWISA
                     ICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITG
                     VAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFAT
                     PKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFL
                     LVGAIHVYINVMQLPMVKRYFK"
     gene            4382..5023
                     /locus_tag="VWX69_000525"
     CDS             4382..5023
                     /locus_tag="VWX69_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9191920.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVAFAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            5041..5271
                     /locus_tag="VWX69_000526"
     CDS             5041..5271
                     /locus_tag="VWX69_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191921.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            5307..5387
                     /locus_tag="VWX69_000527"
                     /pseudo
     CDS             5307..5387
                     /locus_tag="VWX69_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5668..7431
                     /gene="aspS"
                     /locus_tag="VWX69_000528"
     CDS             5668..7431
                     /gene="aspS"
                     /locus_tag="VWX69_000528"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU9191922.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            7409..8350
                     /locus_tag="VWX69_000529"
     CDS             7409..8350
                     /locus_tag="VWX69_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9191923.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(8470..8550)
                     /locus_tag="VWX69_000530"
                     /pseudo
     CDS             complement(8470..8550)
                     /locus_tag="VWX69_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(8686..9672)
                     /locus_tag="VWX69_000531"
     CDS             complement(8686..9672)
                     /locus_tag="VWX69_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9191924.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(9682..10482)
                     /locus_tag="VWX69_000532"
     CDS             complement(9682..10482)
                     /locus_tag="VWX69_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU9191925.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(10735..11577)
                     /locus_tag="VWX69_000533"
     CDS             complement(10735..11577)
                     /locus_tag="VWX69_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9191926.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(11579..12871)
                     /locus_tag="VWX69_000534"
     CDS             complement(11579..12871)
                     /locus_tag="VWX69_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9191927.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(12982..14253)
                     /locus_tag="VWX69_000535"
     CDS             complement(12982..14253)
                     /locus_tag="VWX69_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9191928.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            14803..16320
                     /gene="malQ"
                     /locus_tag="VWX69_000536"
     CDS             14803..16320
                     /gene="malQ"
                     /locus_tag="VWX69_000536"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU9191929.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            16346..18604
                     /locus_tag="VWX69_000537"
     CDS             16346..18604
                     /locus_tag="VWX69_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEU9191930.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(19648..20220)
                     /locus_tag="VWX69_000538"
     CDS             complement(19648..20220)
                     /locus_tag="VWX69_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191931.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(20842..21690)
                     /locus_tag="VWX69_000539"
     CDS             complement(20842..21690)
                     /locus_tag="VWX69_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9191932.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            21842..22120
                     /locus_tag="VWX69_000540"
     CDS             21842..22120
                     /locus_tag="VWX69_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191933.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            22122..24185
                     /locus_tag="VWX69_000541"
     CDS             22122..24185
                     /locus_tag="VWX69_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9191934.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLVRTKELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(24263..25519)
                     /locus_tag="VWX69_000542"
     CDS             complement(24263..25519)
                     /locus_tag="VWX69_000542"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU9191935.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            25661..28126
                     /locus_tag="VWX69_000543"
     CDS             25661..28126
                     /locus_tag="VWX69_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9191936.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            28191..29102
                     /locus_tag="VWX69_000544"
     CDS             28191..29102
                     /locus_tag="VWX69_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU9191937.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            29332..30030
                     /gene="dapD"
                     /locus_tag="VWX69_000545"
     CDS             29332..30030
                     /gene="dapD"
                     /locus_tag="VWX69_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU9191938.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            30098..31228
                     /locus_tag="VWX69_000546"
     CDS             30098..31228
                     /locus_tag="VWX69_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU9191939.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            31240..31779
                     /locus_tag="VWX69_000547"
     CDS             31240..31779
                     /locus_tag="VWX69_000547"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU9191940.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            31763..32440
                     /locus_tag="VWX69_000548"
     CDS             31763..32440
                     /locus_tag="VWX69_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU9191941.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(32512..33411)
                     /gene="galU"
                     /locus_tag="VWX69_000549"
     CDS             complement(32512..33411)
                     /gene="galU"
                     /locus_tag="VWX69_000549"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU9191942.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(33433..34449)
                     /locus_tag="VWX69_000550"
     CDS             complement(33433..34449)
                     /locus_tag="VWX69_000550"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9191943.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            34661..35101
                     /locus_tag="VWX69_000551"
     CDS             34661..35101
                     /locus_tag="VWX69_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9191944.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(35224..35640)
                     /locus_tag="VWX69_000552"
     CDS             complement(35224..35640)
                     /locus_tag="VWX69_000552"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9191945.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(35708..36358)
                     /gene="phoU"
                     /locus_tag="VWX69_000553"
     CDS             complement(35708..36358)
                     /gene="phoU"
                     /locus_tag="VWX69_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9191946.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(36373..37125)
                     /gene="pstB"
                     /locus_tag="VWX69_000554"
     CDS             complement(36373..37125)
                     /gene="pstB"
                     /locus_tag="VWX69_000554"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9191947.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(37127..37942)
                     /gene="pstA"
                     /locus_tag="VWX69_000555"
     CDS             complement(37127..37942)
                     /gene="pstA"
                     /locus_tag="VWX69_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9191948.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(37935..38798)
                     /gene="pstC"
                     /locus_tag="VWX69_000556"
     CDS             complement(37935..38798)
                     /gene="pstC"
                     /locus_tag="VWX69_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9191949.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(38916..39791)
                     /locus_tag="VWX69_000557"
     CDS             complement(38916..39791)
                     /locus_tag="VWX69_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU9191950.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(39958..41289)
                     /locus_tag="VWX69_000558"
     CDS             complement(39958..41289)
                     /locus_tag="VWX69_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU9191951.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(41290..41997)
                     /locus_tag="VWX69_000559"
     CDS             complement(41290..41997)
                     /locus_tag="VWX69_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9191952.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(42081..42557)
                     /locus_tag="VWX69_000560"
     CDS             complement(42081..42557)
                     /locus_tag="VWX69_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU9191953.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            42564..43091
                     /locus_tag="VWX69_000561"
                     /pseudo
     CDS             42564..43091
                     /locus_tag="VWX69_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(43406..45097)
                     /locus_tag="VWX69_000562"
     CDS             complement(43406..45097)
                     /locus_tag="VWX69_000562"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU9191954.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            45233..45679
                     /gene="argR"
                     /locus_tag="VWX69_000563"
     CDS             45233..45679
                     /gene="argR"
                     /locus_tag="VWX69_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9191955.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            45730..48264
                     /gene="mutS"
                     /locus_tag="VWX69_000564"
     CDS             45730..48264
                     /gene="mutS"
                     /locus_tag="VWX69_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU9191956.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            48411..50105
                     /gene="patA"
                     /locus_tag="VWX69_000565"
     CDS             48411..50105
                     /gene="patA"
                     /locus_tag="VWX69_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU9191957.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT        14526 a         9534 c        10938 g        15202 t
ORIGIN      
        1 ctaaagctat tcttgatgta gaacttagaa caagaaggga gattatctat gaaactattg
       61 tttagaaatc cagcttatag aattttgact ttatcacgct tcttcaatgc ttttggtgct
      121 tcgattttca acctggtctt tatcgtctat gcatcgacct tgtcacaagc atcttttgct
      181 gttgctatgg cgaatattgt catgattctt ccgaccctct ttacagtttt tgtagggatt
      241 cgggcagatt acacgaggga caaggtcaaa tggatggtct atagcggttt gtttcaggcg
      301 gttctatttt tcctagcagc cctagttgtt cagcaagcta gtctctttgc cttttctagc
      361 ctgtgtttga tcaatgtcat tagtgatgtc atcagtgatt ttgcaggtgg cttgcgcatg
      421 cctcttatta aggaaaaagt agctgaagat gatctgatgg aggcttattc tttttcacag
      481 ttcatcacct atatttcagc tattggtggt caagctttcg gagtctggct cttagctcta
      541 tcggtcaaca atttttctct cgttgcggga atcaatgcct gctttttcct agtatcagcc
      601 actatcctct ttttaggaaa aagcaaattg agcctgtcaa tgtcatctgc tgatggtgaa
      661 aacttaaaaa atgagaagct ttctatcaaa gaccagttcc taacaattta ccgaaattta
      721 cgtctcgttt ttcttaaaag tgggcagaaa aactttggtt ttatgctctt tgctgtcttg
      781 cttattaatt ccttgggtgg cgctttgggt ggaatttata atatcttctt tttgagccat
      841 tctctcttga atttttctta tacagaggca ctatttatca atcaattctg tgttttagta
      901 gcaatcatca tcagtagcct tacgggcaat gattattttg ggaagcagtc cttgcctaga
      961 ttgatgatgt gggcgaccgt aggacttagt ctagttggtt tggctaattt attcaatcaa
     1021 gtcgtgcttg gtttgctatt tctcttcttt accctgtatg tgtctggtaa agttcaacca
     1081 aagattagtg ccatgctcat gaaaaatcta gctccagagg ttctagctcg tactagtaat
     1141 tttttaggtc tattgtttac cttatccata cctgtgggaa cagcttgttt ttcactagta
     1201 gccgtatgga atatacagtt gacttggatg ctatttgttg gtctttcctt gctagctatt
     1261 tttttgacaa ttcttaatct caaaaatgat atctaaatcc taattttttt cttactgttt
     1321 taatcccttt atttgtggta aaataagact attaagttta aagaggattc cctatgaaat
     1381 tacaaaaacc aaaaggaacg caggatattt tacctgctga atctgctaag tggcagtacg
     1441 ttgagggctt tgcccgtgag attttcaagc gctataacta tgcagaagtg cgcacgccta
     1501 tttttgagca ttacgaggtt atcagtcgct ctgtcggaga tacaacggat atcgtaacca
     1561 aggaaatgta cgatttttat gacaagggtg accgtcatat taccctccgt ccagaaggaa
     1621 ctgcgcccgt tgtccgttcc tatgtggaaa ataaactctt cgccccagaa gtgcaaaagc
     1681 caagcaagtt ctactatatg ggacctatgt tccgttatga gcgtccacag gcagggcgct
     1741 tgcgccaatt ccaccagatt ggtgttgagt gttttggctc tagcaatcca gctaccgatg
     1801 tggaaacaat ctctatggca gcctattttt tgaaggaaat cggtattcaa ggtgtcaaat
     1861 tgcacctcaa cactcttgga aatcctgaga gccgtgcagc ctaccgccaa gccttgattg
     1921 actatttgac accgctcaag gagaccttgt ctaaggatag ccaacgtcgc ttggaggaaa
     1981 atcctcttcg tgtcttggac tctaaggaaa aagaagacaa ggtggcagta gagaatgcgc
     2041 cgtctatctt ggactttctt gatgaagaaa gccaaactca ttttgatgct gtgcgtcaga
     2101 tgttggaaaa tcttggagta gattacatca tcgataccaa tatggtgcgt ggtctggact
     2161 actacaacca caccattttc gagtttatca cagagattga gggcaatgac ttgacagtct
     2221 gtgcgggtgg tcgctacgat ggtttggttg cttactttgg aggccctgaa actgctggat
     2281 ttggttttgg gcttggtgta gagcgcctgc ttctcatcct tgaaaaacaa ggcgtggccc
     2341 tccctatcga aaacgcccta gatgtctata tcgcagtctt gggtgatgga gcaaatgtca
     2401 aagccctaga actagtccaa gctcttcgcc aacaaggttt caaagcagag cgtgattacc
     2461 tcaaccgtaa gctcaaagct cagttcaagt cagcagatgt ctttgcggct aagaccctca
     2521 tcaccctagg agagagcgaa gtcgaaagcg gacaagtgac ggtcaagaac aaccaaaccc
     2581 gagaagaagt gcaagtgtca cttgagacaa tcagccaaaa cttctcagaa atctttgaaa
     2641 aactaggatt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg
     2701 ctcaaaacat ggttttgagg ttgtagatga agctgacgtg gtttgaagag attttagaag
     2761 agtattaatg atagataaag tggtcaggaa cttactcctg acctttttcc tttgcaaaat
     2821 gacaaaaatc ataaactttt tgacaactat acttgtcaaa aagaaaaaga tgtgttacga
     2881 tgtaagcaag ttaagagaaa agaagaaagg agctatgatg tgggtactag gatttatact
     2941 atttatgatt ttcttttatt ctaataattc taaaaaaatc aagaaactag agaataaaat
     3001 caaaaaactt gagcgaaaag agaaaggaaa cgcagaaatg tcgagattat ttcaagaaat
     3061 gattggaaag gaaccaatta taacgggagt gtatattggg ccagataact gggaagttgt
     3121 ggatgttgat gaggaatggg taaagctacg acgtgtagat aatacgggaa aagaaaaatt
     3181 caagttgcaa cgcattgagg atatccaaac cgttgaattt gacggagagt aggtgtgtaa
     3241 catgcaactt aaaaatcgtc taaaagagct tagagctcgc gatggtctca atcaaaccga
     3301 cctagccaaa ctggcagggg tttccagaca gaccattagc ctactagaac gggatgagta
     3361 caccccatcc attatcattg ccctgaaaat atctcaaatt ttcaacgaaa cagtcgaatc
     3421 ggtatttcgt ttggaggagg acgagtgatg aacaagtata aagtgattta ttatgtagtg
     3481 gtcatagctt tattagtcag tgtatttcta ctgattggga tggacctaag ctggtttaat
     3541 ctctatcaaa gcgaccaatt tgtttgggtc tactttgctc tcatcccagt aattgaatgg
     3601 attgaaaaga aatccaaaaa tctagcaagt gaaaaaggag aatgaatatg aaaaagaaac
     3661 gtagattgtt atttttgatg tctattgtct tgggcatgtt tgtagggatg tttaaggcac
     3721 gtgtcgaatc ccacgaaatt attttagatg taaaagcctt gatgccatgg atatcagcta
     3781 tttgtttact gataggtttc attagtatgt ttttgacttt caatttctta aagaaaagca
     3841 gaaaatttca ttccttgtat caagaggaaa tggatgacga tctgaatgaa acctattatg
     3901 tgcaaatgta tcggaatctt gagtttggaa ccattgcttt taatattaca ggtgtagcga
     3961 ttccattggc tatttttatt tcattaagtg aggtgattat attgcataca aaccctcaaa
     4021 catttttcct ttctttctta ctctttgtgg tattcttagt cgctcaaaaa tctcttttta
     4081 aaaccattgc gattgttcgt cagtttgatt tggaattttt cgctacacca aaggatgtct
     4141 tgaactatat aaattcttat gatgaagggg agcgtcaggc taatttggaa cagagttttc
     4201 gaattttatt ccaattacac caatatgtct taccagcctt atatattttt cttattatca
     4261 tttctttctt gacaggagag attcagttac tagctttctt gcttgtagga gccatccatg
     4321 tttatatcaa tgtgatgcag ttacctatgg taaaacgtta tttcaaataa aggagttatc
     4381 tatgaaatta cttaaaaacc ttggctggat tcttctagcc cttctatcct ttttatttat
     4441 ctatggcttt attcaggggc tcgcgactgc gtcgcttgct ttaggcgctt caccctatgc
     4501 tgttactcta ctctatgtgg cctttgctgg agtatatgtg tacggcattt acaaatggta
     4561 tcagaaggct cctgttcata ttgagaagag cggctttaat cgatttattt ggcttcctgt
     4621 cttggtttgg ttcttatctc tggtcgttca attcttcttg ccagatgatc cttcagtaaa
     4681 tcagcaaata gcgacagact tgaccttgtc tcaaccactt ttctcattct ttgctgtggt
     4741 tatttttgct cctttgacgg aagagattgt ttttagaggg atgttagcac gctatctctt
     4801 tcctaagcag gacaatagta aacgaaccct gatttttctt ctggtatcta gtcttctatt
     4861 tgccttgatt cattttccag gtgatgtgca acaatttttt gtctatttta gccttggttt
     4921 tagtttgggt ttggcttaca ttagcagaaa aggtctggtc tacagtattt ctcttcacgc
     4981 tttgaataat ttagtcggct ttttgatgat tctcatgcta taatagagtc aggaggtcac
     5041 atgaaacgag taattttatt agcagtgatt caggcagtcg ttctattttt catcattgga
     5101 gcgctagctt atgccttcaa aggcgatttc ttctataact atctagcagt tgtctttgct
     5161 cctattgcag gtgtactgcg ttttgggacg gcttacataa cggaaattgt cttgcctcga
     5221 aaggcagccg aaatcgctga aaagcgtaaa gcaggcaaaa attcaaaata aaagagtccg
     5281 gtgaagttca tcggattttt gtattatact caatgaaaat caaagagcaa actaggaagc
     5341 tagccgcagg ttgctcaaaa cactgttttg aggttgtgga tgaaactgac aaagtcagct
     5401 caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt cagctcaaaa catggttttg
     5461 aggttgtaga tgaaactgac gaagtcagta accataccta cggtaaggcg acgctgacgt
     5521 ggtttgaaga gattttcgaa gagtattagc gctaattttt agggctttca cctgactttt
     5581 aaagactggc aaacttttct gatgattttc atgaagagcc tgcgctttta tggtaaaata
     5641 gtaacagaat aaaagaggag agaaataatg aaacgtagta tgtatgctgg tcgtgttcgt
     5701 gaggaacaca tcggacaaga aataaccttg aaaggatggg ttggccgtcg tcgtgacctt
     5761 ggtggtttga tctttatcga tcttcgtgac cgtgaaggaa tcatgcagtt ggttatcaac
     5821 cctgaaaaag tatctgcaga ggttatggca acagctgaaa gccttcgtag cgaatttgtt
     5881 attgaggtga ctggtcaggt cgctgcgcgt gagcaagcca atgataagtt gccaactggt
     5941 gcggttgagt taaacgtgac agctcttatt gtgcttaaca cagctaagac aacaccattt
     6001 gagattaagg atggcattga ggcaaatgac gatacacgtt tgcgttaccg ttaccttgac
     6061 cttcgtcgtc cagaaatgtt ggaaaatctt aaacttcgtg ccaaggtgac ccactctatc
     6121 cgcaactact tggatgagtt ggagtttatc gacgtggaga caccattcct ttctaagtca
     6181 acgcctgaag gggcgcgtga ttatttagtg ccgtctcgtg ttaataaggg gcatttttac
     6241 gctcttcctc aaagtccaca aatcacgaaa cagctcttga tgaatgctgg ttttgaccgt
     6301 tactaccaaa tcgttaaatg tttccgtgac gaggacttgc gtggagaccg ccagcctgaa
     6361 tttactcagg tcgacttgga aacgtccttc cttactgagc aagaaatcca agatattaca
     6421 gaaggcttga tcgcgcgcgt gatgaaggaa acaaaaggca tcgaagtaac gctaccgttc
     6481 cctcgtatga aatacgatga tgctatggct ctttacggtt ctgacaagcc agatactcgt
     6541 tttgacatgt tgcttcagga cttgacagaa gtggtcaaag gtgtagactt taaagtcttt
     6601 tcagaagcac ctgctgtaaa agcgattgtg gtcaaaggag ctgcggacaa ctattcacgt
     6661 aaagacatcg acaagatgac ggaagtagcc aaacagtatg gtgccaaagg tcttgcttgg
     6721 gtcaaggtgg ttgatggaga attaaacgga ccagttgcca agttcttgac tggtatccaa
     6781 gaagaattga caacagcgct tgctcttgaa gataaggact tggttctctt tgtggcggat
     6841 acgcttgaag tggctaatgc aacactgggt gcccttcgtg gacgtattgc taaagagctt
     6901 ggcttgattg ataatgataa gttcaacttc ctttgggtgg ttgactggcc gatgtttgaa
     6961 tggtctgaag aagaaggccg ctacatgagc gcccaccatc cattcacact tccacaggaa
     7021 gagactgctc acgaattaga aggtgatttg gctaaggttc gtgccattgc ttacgatatc
     7081 gtcttgaacg gttatgagct tggtggtggt agccttcgta tcaaccaaaa agaccttcaa
     7141 gaacgcatgt tcaaggctct tggtttctca actgaagaag ccaatgacca gtttggtttc
     7201 cttcttgaag ccatggacta tggtttccca ccacacggtg gtttggctat cgggcttgac
     7261 cgttttgtca tgttgcttgc tggagaagaa aatatccgtg aagtcattgc ctttcctaag
     7321 aacaacaagg caactgaccc aatgacacaa gctccatcaa cagtcgctct caaacaacta
     7381 gaggaactca gcttacaagt agaagaagat gaaacaaaca aaacgaatta agcggtggcg
     7441 ctattatctg cgccgctttg cttatcagat aaaaatttta cgtgtcttac aaagtatctc
     7501 tcgagaaaag tatgatgaga agatttcggc ctctctggtc tatggttttt tatcagcagt
     7561 agcagttaat ttctttttcc aaccagggca tgtgtattcg agtggtgcaa caggtctggc
     7621 acagattatc tctgccttga gtaatcactg gtttggtttt catattccga tttcgctaag
     7681 cttctacgcc attaacttcc ctttgatggt cttagcttgg tatcagattg gccataagtt
     7741 caccgtcttt acctttatca cggtatctat gagttccttc tttatccagt ttgtccctgt
     7801 ggcaaccttg acggaggatc ccattatcaa ttcccttttt gggggtgttg ttatgggttt
     7861 ggggattggt tttgctcttc gaaacaatat ctccagtggt gggacggata tcgtcagcct
     7921 gactattcgc aagaaaacgg gtaagaatgt cggtagtatt tctttcttgg taaatggaac
     7981 tatcatgctg atagcaggtt tgacctttgg ttggaaatac gctctttatt ctatgattac
     8041 catctttgtc tctagccgtg tgacagacgc agtctttact aagcaaaagc gtatgcaggc
     8101 catgattgtg acaaatcatc cagagaaggt aattgaaaaa atccataaaa aattgcaccg
     8161 cggagcaacc atgatccacg atgcagaagg aacctataat cacgagagaa aggcagtttt
     8221 aatcactgtc attacacgtg cagagtttaa tgaatttaaa cagattatga cacaagtgga
     8281 tccaagctcc tttgtctctg tctcggaaaa tgttcatatt ctaggaagat ttgttgagat
     8341 agataattag tgattaatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc
     8401 cgtatatatg ttactgactt cgtcagttct atctgcaacc tcaaaaccat gttttgagct
     8461 gacttcgtca gttctatcca caacctcaaa acagtgtttt gagcaacctg cggctagctt
     8521 cctagtttgc actttgattt tcattgagta taaaaagatc ttgggaaaag actcaatttc
     8581 agtagaaaag gaagtaaatc ttcccacaat aaaacgcata gtatcaagtt ttttcaatac
     8641 ctgatagtat gcgtttttgc ttttaacgac tctttgccca gtctcttatt tttcgataat
     8701 tttgtgggcg atcaattgac ggtaacaaat ttgtttattg tttttattat cattaataat
     8761 ctggagaata gtttcaaggg aaacacgacc aagctctaaa ctattgatat cgacataggc
     8821 tgccaagttg agcttgggat taaccgagtc aaagctgaga acagggacat ccagctggtg
     8881 tttggcaata tagttacaaa caccttcagc taggaggcta tcggttgtga tgatagcatc
     8941 aatttgtgga tcgtgcttga ataatcgctt gctaaattta tagccctttt cttccagaaa
     9001 ctcgtcggca aagtagatgc gattgttgtc agtggtaagt ttgtaatgtt taagcgcctg
     9061 ttcatagcct gttaaacggt ctttggtcac gaagagcttt ttacttcctc cgataaaggc
     9121 aatgcgtttg cagccttttt tgatgaaata ttcagtcgca tcaaaaccag cttgaacatt
     9181 gtcgttgtcg acaagtggga tgaaaggaga tagagattta cctaggataa ggaaggggaa
     9241 ctgttcttct gcgacgagtt ttacgagagg gtcttcttct tgggcataga gaaagattag
     9301 cccatctaca cgcttgccgt agaccatttg tgaaatagcg ttgagacgct ccttctcatc
     9361 tttccctgtt gctatctgaa tggcatagtg gttttcagat gcgacttgag agatgccacg
     9421 tagaaccgat ggaaagaaag gattctggta gaaggcgtct gagtcatcag gaagaactaa
     9481 tccgataacc tgagtatagc tgcttaccaa gctacgagcg ttgaggtttg ggtggtagtt
     9541 gagttccttc atagccttgc gaacgcgttt ttttgtttcg tcgctaatgg ttgatttatt
     9601 ttgaataaca cgggttacgg ttgaaggcga aacaccagca gccttggcca cgtctttaat
     9661 cgtaacgggc ataaaaatct cctatttatg gtaatttgga tcacggaaat gtgttttata
     9721 aaagatagtg accagataca gaacaaaaag aatattttgt acagtaatca gggttgtcat
     9781 attttggcca aataatccca aaataagtgt aatcagagtc ggcaatccta aacagttcaa
     9841 gataaagtga tagcactctt taaaggttct aaatgaaaag aggcgtgatt tcttagtgat
     9901 ataaaggaga agactagctc ctagagagac gataaagaaa ttcaaaccaa agaggaagct
     9961 cgcaccgaga actaggaaga ggctgatata gacacgattt tgttggtacc agtctttaga
    10021 aattgcttgg gtcaagctgt ctttgctttt gaaactctca gtctgaatgg ctcggtaaga
    10081 gatgcgggtc agttccttgc tttccttgct gatgactagc tcatttgtat cgaaatgcag
    10141 ttgcaagttc ttaggtaatt ccttgatttg acttggacca atcacaacag aagaggcttg
    10201 actaactgtt ccagtataag ttaatgtgcc atcgacaatt gtagcatgtt cagagagatc
    10261 ctggacaacc tcatttgtca gaggttcata gacattatcg ataaaagttt ctagcggata
    10321 ggtctcctgg gagctgtttt ggatagcaat gggtaccata gacaagctga taaggaagat
    10381 actggtaaag agaagttgaa accagttgag cccgaaacgt ttggacaggg gcttacgaaa
    10441 ccccaaaata cttgaaaaaa aggaaaatgg atatggaagc ataggtatct ttctaaaagg
    10501 tgttttctat ataagtatta ttatatagag aaatgcgctt tatttcaagt ctaggagaaa
    10561 aattgcttgc tacaaggata ttatttacag tgacaattgc taataatcaa tgaaaatcaa
    10621 agtgcaaact agccacaggt tgctcaaagc acaactttga ggttggagat aaagctgacg
    10681 tggtttgaag agattttcga agagtataaa atgaaaaagg gtggcgggga taaattatcc
    10741 cttgtcgcca ccacttgtaa gtcctgaaac aaagttcttt tgtaggaaga agaagagaat
    10801 acagattgga agggcgatga ggatagcacc tgctgagaag taggcaatct tcaagttttt
    10861 cgcattgtta acgaaggttt ggagacctac ggcaacagta aagtattctt tctcacgaag
    10921 caagaaacta gagaggatgt agtccccgaa aggtcccatg aaggcccaga gagcttgtac
    10981 ggcaaccatt gggcgaacaa gtggaagaac aatttgccag aagcggcgga agtgtcctgc
    11041 accgtctagt tttgcagatt cgtctaaaga cattggcact gtatcgaagt agcctttcat
    11101 gagccaagca ttcatcggga taccaccacc aacgtagagg aagatgagga accagttgtg
    11161 gttaagggcg ttcaacataa gcgccataac gaagaaggct gtcaaagcgg ccatagttgg
    11221 caccatttgg atgatcaaga agaagaccaa actttgttta cgagccaaga agttgtaacg
    11281 gctgtaagca taaccagcaa gtacgatgat acttgtttga acagccatgg taattaaggc
    11341 gataatcaaa gtgttgaggt accaagtacc gtacaaggtt tcagtgaaga ggcctttaaa
    11401 gttatcaaaa ttgaggtcga tattagtatc tagtttaaag gctgagacgt tacctgcttt
    11461 aaaggctgac ataatggtaa tcaacagtgg atagataatt acaattgata gaccaatcag
    11521 gtaaaggtaa gtaaggcttt gagtcagtct acgtttgagt ttaattgagt tattcatctt
    11581 agacgtcctc catatcaaat gcgtgtagtt tcttgaatgc gatcatagag attgagatga
    11641 caatgataga gataatcaag gtaacagctg ccgccattga gtattgagga gatgtacctg
    11701 ttgtcaaacg gtagatccat gagatcaaga tatcggttga accagctcca cctccgacac
    11761 taccaggtcc tccaccattg aagaggtaca tgatagagaa gttgttaaag ttgaaggtgt
    11821 attggctaat caaagtaggt gccgcaacag ccaaaatcat tgggaaagtg atgttgcgga
    11881 atttttgcca agcgttggca ccgtcaatat aagctgcttc gtaaaggtcg ttaggaatag
    11941 attgcaagat acccaaggtc agaacgtaga tgtatgggaa tccgagccaa ccttgcatca
    12001 taatcaaggc aatcttagtc caagttgggt ctgttttcca aggaataaga gctccatcaa
    12061 ggaaaggaag gaatttagcc aagattggca atacttgagt gttgatagca ccgacactat
    12121 cgttaaacat gtttgagaat gtcaagatag tgatgaaggc tgggacagcc caaggaagaa
    12181 ggaaaataac accaaagata cgttttcctt tgataaatgg ttggttggca atgatagctg
    12241 tgaagatacc aattacgatt tgtaaagtag aagctgccaa agcccaaatg atagtccaag
    12301 aaagaacaga accaaaggca gaacggaagg tactcaagct ccaaatgttt gtaaagttgg
    12361 tcaaaccaac ccagtccaac aacttgtttg gtggcaagtg ttggaagtcg tagttggtaa
    12421 aggcgatcat caaggttacg ataactggga agataatcgc gaaggtcatg gcaacataag
    12481 atggaatgat caagaggtaa gggaagccat tttcataaat ccctttgatc atgtctttga
    12541 gtgtgcgtgg aactggaatt ccattgttaa tgcgttttgc aatcgtatgt gcatctttga
    12601 tatttgagaa ataaaagagt acataaacga ttacaaagat tagatggaag gcaccacgaa
    12661 tcagcataaa gagggaatta tcacgacctg gtttgtcacc aagagtgatg aggttgctca
    12721 attcaggggt tgcaagtgct aggaagtaaa ggacaaatac gatggttaca ccaaggaaga
    12781 taaaaccttt ggctttttgt ttattgtaaa tctgtcctaa cccaggaatg atagacagca
    12841 gggctgcttt actaggttgt tgcttttcca tattaactcc tttcatagga tactactttt
    12901 ttataagaaa gctaaattat ttgtgtctct attgataaat tcaaaggggg atttgatttc
    12961 cacccccctt gaacaaattt tttattcacc aaatttttgt ttgattgttt ctttgatcaa
    13021 tgttacagca tcgttagcag ctgttttagc atctttttga ccacttacag catcaaagag
    13081 catatttttc gctggatccc aaactgcaga catttgagag atgtttggca gtggttgagt
    13141 gttcttgaac tgtttgataa cagctgttgt caactcatcg tttttacctt cagcgtatga
    13201 acgagcctca gtattagctg ggatttcgtt agtcttatca tataatactt tttgttgttc
    13261 agttgcaaca aggaagtcta caaatttttg agaagcttca aggttcttaa cggcttgagg
    13321 aatgacccaa gctttaccac caccgaatgc agcatattct tttccatttg gaagagttgg
    13381 gatagttgca actccgtagt ttactttagc atctttaaag gcttgagctt tccaaggtcc
    13441 gtcgatgata gcagctgttt taccttcttg gaattgagtt tggattaagt ttccagcacc
    13501 ttctgtatct tgcatacctt taggccattt ttcgtaccaa gatttagcgt agttgatacc
    13561 tacgatagaa ccgtcgtttg caagaccgat gtctttagcg tctttaccgt tttggccaaa
    13621 gacgtaagca ccgttaccgg caagaagtcc atatgtatag tagaagtttg tccagtcagc
    13681 taggaaggca gtagttttac catcttcacc agcgaatgcg tatttgctat ctttagcaag
    13741 gttttccaag tcagcaaatg tttttggagc atctttcacc aagtctttgt tgtagtacat
    13801 aacaagtgac tcgataacgg caggagcacc gtaaacttta ccattagcag ctgttacaag
    13861 agatttagtt gtgtcgtctg ttttagcacc atcgctcaat ttcacttctg aaagttgtcc
    13921 gtcagaacca aggctaccta cacggtcgta tggagccatc ataacatcag ggacattacc
    13981 agattggttg tcaagagaaa gtttatcaag acctcctaga gcatcaccag ttttaagagt
    14041 gacttttact ccagcttctt tttcataagc tttagcaacc tcttcaatat agctcttata
    14101 tccctcgtct acatatacag tgagttcttt gacttcagat gaaccagaat cagcaggctt
    14161 atcagcagtt ttgcttccgc aagctaccaa aagcaagcta gcaagtgtaa cagttccaag
    14221 caccgcagtg ctcttcataa atttagatga catagtgtat tcctcccaaa gaatagcaag
    14281 ttttattgat aaggaaacgc aaacgttttc ctttatgagc ttagtatagc acaaatagaa
    14341 aacggttgca agtatttttt gtaaaaattt taaaaaattt ttaagcttga tttgatagca
    14401 taattttgca ttttaataga agaaaagtat gaaatagata agaatacagt atttttaata
    14461 aaaatatatg gaatctgtct aaagagggaa accaggaggg gctacctccc tggttctaat
    14521 ccctatctat tttctatgga cgtttgtgct ttgttacata taaattcaag ctccctaagg
    14581 aggttttgta ctttgtagac tgtctcgtga gagtcaaacc ttaggattag atagttttaa
    14641 gttatctttg ctaaaatgag ttagtctcct taaaaataat caaaaaagtt ttttaaaaac
    14701 gcttgcaatt atgcttgaaa aggagtatac ttataagtaa cgcaaacgtt tgcgtctgca
    14761 aaatacgcaa cgttccatta ttttaacaca cgaggtgcta ttatgaaaaa acgtcaaagt
    14821 ggtgtgttga tgcacatctc ttctcttcca ggagcttacg gaatcggatc atttggtcaa
    14881 agtgcttacg acttcgttga tttcttggtc cgtacaaaac aacgttactg gcaaatcctt
    14941 ccattaggag caactagtta cggggattct ccttaccaat ctttctcagc cttcgcagga
    15001 aacactcatt ttatcgattt agatatcttg gtggagcaag gtttgttgga agcaagtgac
    15061 cttgaaggag ttgactttgg tagcgatgcg tctgaagttg actatgctaa aatctactat
    15121 gcacgtcgtc ctcttttaga aaaagcggtg aaacgtttct ttgaagtcgg agatgttaaa
    15181 gattttgaga aatttgctca agacaaccaa tcatggcttg agctctttgc tgagtatatg
    15241 gctatcaaag agtattttga caatcttgct tggactgaat ggccagatgc agatgctcgt
    15301 gctcgtaaag cttcagcact tgaaagctat cgtgagcaat tggcagacaa gttggtttac
    15361 caccgtgtga ctcaatactt cttcttccaa caatggttga aattgaaagc ttacgctaac
    15421 gacaaccaca tcgaaatcgt tggggacatg ccaatctacg tagcggaaga ttcaagtgat
    15481 atgtgggcaa atccacatct cttcaaaaca gatgtcaatg gtaaggctac ttgtatcgca
    15541 ggatgcccac cagatgagtt ttctgtaact ggtcagcttt ggggtaaccc aatctatgac
    15601 tgggaagcaa tggacaaaga cggctacaaa tggtggattg aacgcttgcg tgaaagcttc
    15661 aaaatctacg atatcgttcg tatcgaccac ttccgtggct tcgaatctta ctgggaaatc
    15721 cctgctggtt ccgatacagc agcacctggt gagtgggtga aaggtccagg ctacaagctt
    15781 tttgcagccg ttaaggaaga acttggtgag ctaaacatca tcgcagaaga ccttggcttc
    15841 atgacagatg aagtgatcga attgcgtgaa cgtactggct tcccaggaat gaagattctt
    15901 caatttgcct tcaacccaga agacgaaagc attgatagcc cacacttggc acctgctaac
    15961 tcagttatgt acacaggaac acacgataac aatacggttc ttggttggta ccgtaatgag
    16021 attgatgatg cgactcgtga gtacatggct cgttacacga accgtaaaga atacgaaaca
    16081 gtggtacacg ctatgcttcg tacagtattt tcatcagtta gctttatggc aattgcaact
    16141 atgcaagatt tactagaatt ggatgaggca gctcgtatga acttcccatc tacccttggt
    16201 ggaaactggt cttggcgtat gactgaagat caattgacac cagctgtcga ggaaggtttg
    16261 cttgacttga caacaattta tcgccgaatt aatgaaaatt tggtagattt aaagaaataa
    16321 gacaataatc aggagacaac taaacatgtt atcactacaa gaatttgtac aaaatcgtta
    16381 caataaaacc attgcagaat gtagcaatga agagctttac cttgctcttc ttaactacag
    16441 caagcttgca agcagccaaa aaccagtcaa cactggtaag aaaaaagttt actacatctc
    16501 agctgagttc ttgattggta aactcttgtc aaacaacttg attaaccttg gtctttacga
    16561 cgatgttaaa aaagaacttg cagctgcagg taaagacttg atcgaagttg aagaagttga
    16621 attggaacca tctcttggta atggtggttt gggacgtttg gctgcctgct ttatcgactc
    16681 aattgctact cttggtttga atggtgacgg tgttggtctt aactaccact ttggtctttt
    16741 ccaacaagtt cttaaaaaca accaacaaga aacaattcca aatgcatggt tgacagagca
    16801 aaactggttg gttcgctcaa gccgtagcta ccaagtacca tttgcagact ttactttgac
    16861 atcaactctt tacgatattg atgttactgg ttatgaaaca gcgactaaaa accgcttgcg
    16921 tttgtttgac ttggattcag ttgattcttc tattattaaa gatggtatca actttgacaa
    16981 gacagatatc gctcgcaact taactctctt cctttaccca gatgatagtg accgtcaagg
    17041 tgaattgctc cgtatcttcc aacaatactt catggtttca aacggtgcgc aattgatcat
    17101 cgacgaagca atcgaaaaag gaagcaactt gcatgacctt gctgactacg cagttgtcca
    17161 aatcaacgat actcacccat caatggtgat tcctgaattg attcgtcttt tgactgcacg
    17221 tggtatcgat cttgacgaag caatctcaat tgttcgtagc atgactgcct acactaacca
    17281 cacaatcctt gctgaagcgc ttgaaaaatg gcctcttgaa ttcttgcaag aagtggttcc
    17341 tcacttggta ccaatcatcg aagaattgga ccgtcgtgtg aaggcagagt acaaagatcc
    17401 agctgttcaa atcatcgatg agagcggacg tgttcacatg gctcacatgg atatccacta
    17461 cggatacagt gttaacgggg ttgcagcact ccatactgaa atcttgaaaa attctgagtt
    17521 gaaagccttc tacgaccttt acccagaaaa gttcaacaac aaaacaaacg gtatcacttt
    17581 ccgtcgttgg cttatgcatg ctaacccaag attgtctcac tacttggatg agattcttgg
    17641 agatggttgg caccatgaag cagatgagct tgaaaaactg ttgtcttatg aagacaaagc
    17701 agctgtcaaa gaaaaattgg aaagcatcaa ggctcacaac aaacgtaaat tggctcgtca
    17761 cttgaaagaa caccaaggtg tggaaatcaa tccaaattct atctttgata tccaaatcaa
    17821 acgtcttcac gagtacaaac gccaacaaat gaacgctttg tacgtgatcc acaaatacct
    17881 tgacatcaaa gctggtaaca tccctgctcg tccaatcaca atcttctttg gtggtaaagc
    17941 agctccagcc tacacaatcg ctcaagacat tatccattta atcctttgca tgtcagaagt
    18001 tattgctaac gatccagcag tagctccaca cttgcaagta gttatggttg aaaactacaa
    18061 cgttactgca gcaagtttcc ttatcccagc atgtgatatc tcagaacaaa tttcacttgc
    18121 ttctaaagaa gcttcaggta ctggtaacat gaaattcatg ttgaacggag ctttgacact
    18181 tggtactatg gacggtgcta acgtggaaat cgctgagttg gttggagaag aaaacatcta
    18241 catcttcggt gaagattcag aaactgttat cgacctttac gcaaaagcag cttacaaatc
    18301 aagcgaattc tacgctcgtg aagctatcaa accattggtt gacttcatcg ttagtgatgc
    18361 agttcttgca gctggaaaca aagagcgctt ggaacgtctt tacaatgaat tgatcaacaa
    18421 agactggttc atgactcttc ttgacttgga agactacatc aaagtcaaag agcaaatgct
    18481 tgctgactac gaagaccgtg acgcatggtt ggataaagtc atcgttaaca tttctaaagc
    18541 aggattcttc tcatctgacc gtacaatcgc tcagtataat gaagacatct ggcacttgaa
    18601 ctaatactct tcgaaaatct cttcaaacca cgtcagcttt atctgcaacc tcaaagcggt
    18661 gctttgagca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    18721 tacaaattta tactaataca ttttgtaaaa aagcgagttt cgattgaaat tcgctttttt
    18781 aaatgctgtg gatttgggtc aatcttgtct aaaaataggg aaatcctaga tacagtgaag
    18841 gctttaaatg ctggttttta ctgtcttcag ccttatattt tttcgtagtt ggttacctca
    18901 tatctcttgt attcgcttac ataaagtatt ataatataat tgtaggaaag aaggtgtttt
    18961 tatgatatac acacttaaat tggtgttgtt tattaccttt cttgtaataa gcttgttacc
    19021 tgataagatt tttggaaaaa ataaaaaaat ttggaaaata gtttttgcaa tattgacggc
    19081 agtggcagca ttgtcattta tgtactaagt tattttaaga atgtagggaa ataaacccta
    19141 cattttttta gttttttctg ttttctaaat tctatttatc caagagcttc aacatttctt
    19201 gcttcttcgc ttcaagttct gcacgctttt cttcgatttc ggcatgtttt ttctcgagtt
    19261 cagaacaact tgcatcattg ctaaattctt ttcgccatca ggagataggg tgagtctaca
    19321 tgtctattac tcacccaaag cagtcctaca aagcaggaat tttctgttac ttttttggaa
    19381 atagtaacgt ttatacagct ttgacacttc gtatcaaagc gccaaacaca ctccgaggga
    19441 tttacagaaa gcagaaaagg aatgatctgg tataagatca ttccttttct ctctttttct
    19501 ttaagtaatt atatacaatg tacgacgaag tcgtcattgc aatgctgatc caccacctaa
    19561 agggaacttt aaacaacatt gataagataa agaatataaa caacgaaaat acgttatacc
    19621 caattaattt tattgtatat ctcatgatta aaagttaatc cttccgttgt taggaatggc
    19681 atcattttta tcccataatt gtgctaaata agtccccggt gataataaat tcatagcgaa
    19741 ttctaaagca acatcattta caaaccaact acctagatat ctagaaattg ctgaacgaat
    19801 agcacttttt gctgcatgtt ttccttttac tttaattaga tttgcaaggc ctgcagtagt
    19861 tcctcctaat gctaaagcta ttgcagtatc taatagagca cccatttgat taactgtaat
    19921 accttgccaa gctgctctaa atggagagta tgtaggtggg attgtataat cgccttgtaa
    19981 ttgtcggtta attacttctt tgatccattg ttgtgagacg tctggatgaa aagattggat
    20041 ttcgtttgca agtgtattga tttgttcttc tgttagagaa gtgacaggtt gaagttccat
    20101 atttgtttca atttgtgata cttgttcaga agcgtataca gctgaaacac ttggaatcgc
    20161 tgatacaatt aacacaattg acgtcaaaaa aaccgaaata aatttcatta atttgttcat
    20221 gagcttttct cctttttatt tgtatctgct tacattttat catatactgt tattatagtc
    20281 aaaaaaatat gctattatgt taaaaaaata tttttcaaaa tataaatgga cggatttatt
    20341 ttggatttta tttgttattt tgacctgcct ctatattggt aaccatgatt tgtttactct
    20401 caatcatcaa gaattctctt ttcgtggtag cgtttggggt ctggtactgg ccttatatca
    20461 cttattgttc attgataagt ttgtaatttc gaatcgaaaa taaagattag aactatgatt
    20521 gactggctac ttttaatatt gattttggag gaagattttg tctctattat ttattatttt
    20581 aaatttatct attttgtaca agatttattc tttgagacgg gagaaatcga aatacttgat
    20641 ttatacggcc tatatcatat ttggggtaaa tgtagtatat ggtattcaat ggttattaag
    20701 agaactgatt tcaactattt ccccttaatg tgtatggaaa ctataacaaa acgcataaga
    20761 ttaaggtttg tgtacctgtt cttatgcgtt tttataatat tgaagatttt cggtaagttt
    20821 tatacctttg ggaagtctag tttagaatgc tttcccaacc aaaatctctg cttcgatggt
    20881 aatctctgtc agttggctcc agtcaatctt gctctggtca acgtgaaaga ggagaggagt
    20941 catactgagt agggcttgga gttgttctgc tgtgatagtc ttagtcagag aggcagtttg
    21001 actagatagg atggtaaagt gttcctggaa atgctccttg atatcttggt tagaatactc
    21061 cttgtttgtc agctggtcct gtactctttg acggatttct ttgaggtgat tttcagttgg
    21121 gataaccttt atcaagatac cgtctttgga taaaacgcga cgaaattctc catagttggc
    21181 aggtgagaag atatcaagca gaatatccat gttagcgtct tttataggaa gtcgtgccaa
    21241 gtcgccaaca aaccaattga ctgcccagtt gggttcactt ttagcagcga tttggactga
    21301 atctttggag atgtcaaagg catagaaagt tttttcagag tgactttctt gtagtttgcg
    21361 agaatagaat ccttcaccac aaccgatatc caaaattgtt gtggtagttt ttgagcttgc
    21421 aagcaagtca gatacagcat ctaagatagc ttggtaaaag ccggcttcta ggatttgttg
    21481 acggttttga aaattttcct tgttatagtt agcagattgc ttgatttgag gtgctagatt
    21541 gacatagcca aatttcgcca agtcaaaaga atgacggttg cagcacttga aattagtctc
    21601 taacagagtc agattttctt gacagatagg acaggcaaag gcagtcgcag aagcaaaacg
    21661 ctgaagtttg ggcttgagat ttgtattcat agtttaagtg tatcaaaaga ggcaaatgaa
    21721 agcaacttta ggaataagta gatgggagat tcagtagaaa taaaactaat tctccaattt
    21781 atagaatgaa attgctttta tatctaaatt gctatataat aatgataagg aggaaataag
    21841 tatgttaaaa gaagtattaa ccgttgcaaa agttgcgaaa aaatcttcat tatttttggg
    21901 tggtgtcgca tttggtaccc ttggtttgaa aatcttagca agtaaggaag ctaaaaaagg
    21961 ttattctaaa gctttggcta aggcttacaa gttgaaagac gagctagatg catctgtttc
    22021 tgttgtgaag caacatggag acgatgtctt gcaagatgcc aaatatttgt acgagcaaga
    22081 gaaaaaagaa gagcaattag atagccttat aggtgaataa tatgtctttt aaagtgctac
    22141 atagaggata ccaacatatc cgactatcat cttctttttc acttaccttg gatattcaag
    22201 actatcttcg ttccttggcg agagatgaaa aggggattga gtctatccag ttttacatgg
    22261 atcaacagca ctttactcta cgcataaaag aaggcttttc tgtattagat aatgcagaag
    22321 cctttttaaa aagaattgat aaagggaaag tttctgagtt gatgactctt cccattcgta
    22381 gagaagagag tgcttattct attgtttcag gtgcagcggt taagcgtgta ctttttcgta
    22441 gttttgtgcc gtatcctatt cgctatatat ggacttgtta tcaggctttg ggttatatta
    22501 gagaagccta tcaaacacta gcgcgtaagg aactaacgat ggaagtcttg gactgttcgg
    22561 ctattttatt gtctttgttt atgaaccaat ccaagacagc tagcaatatc atgtttatgc
    22621 ttgatttggg gaatcattta gatcagtggt ccttgaaaaa aactgcaaca gatttagaac
    22681 agagtcttct tgcaaaagag agcgatgtat tcctagtaca gggcgatacg gttgttagta
    22741 tcaagagttc cgatgttcaa ataggagatg tcttgatctt atctcaagga aatgaaattc
    22801 tgtttgatgg acaagtagtt tcaggtttag gtatggtcaa cgaaagttcc ttgacaggag
    22861 agagttttcc agttgaaaaa agagagtctg atttggtttg tgcaaataca gtattagaaa
    22921 ctggagagtt acgcattcgt gtaacagata atcagatgaa cagccgtatt ttacagctga
    22981 ttgagttgat gaagaaatct gaagaaaaca agaaaacgaa acaacgctat ttcatcaaga
    23041 tggcggataa agtcgtcaaa tataatttct tgggggctgg gctgacttac ctattgacag
    23101 gttctttttc taaggctatt tctttcctat tggtcgattt ctcctgcgct ttgaaaatct
    23161 ctactcctgt agcttatttg acagttatca aggaagggtt gaaccgtgaa atggtgatta
    23221 aggatggaga tgttctggag aaatatctgg aagttgatac tttcttgttt gataagacag
    23281 gaacaatcac aactagttat cctatagttg aaaaggtgtt accttttgga gactatagtg
    23341 aggaagatat tctcagaatc agtgcctgtc ttgaggaaca catttatcat cctattgcta
    23401 atgccatcgt caagcaagct gagatagagg gaattgaaca tgaggaaatg catgggaaac
    23461 tccaatatat cgcaagcaag gggatcaaat ctcatataga tggccaacca gttcttattg
    23521 ggaattatgt cttgatgcag gatgagcaga ttcatatcag ttcagaacaa aatgctttaa
    23581 ttgaagagta caagagtcac tacaatctct tattcttggc ttatcaaaat gaattgattg
    23641 gaatgttctg cattcatact cctttgagaa aagaagcaaa aacagccttg gataaactta
    23701 aggcacaggg gaaaaaattg attctggcaa caggggacac cttggttagg acaaaggaat
    23761 tagtcaaaga tttgcccttt gatcaggtct atacagactt gaaacctgat gggaaatttg
    23821 agttagtaga gaaactgcag aaagcaggtc acactatttt gatggttgga gatggattga
    23881 atgactcagc ggctttaact ctatcagata tcggtgtggt gatgaatgag agtgcagata
    23941 tttctaagca gatgagtgat atcttattgt tagataatcg tttggatttc ttccaagagt
    24001 tggattcgtt atcatcatct ttgcaaacac tcatcaagaa aaatattcaa gataccgttg
    24061 tcgtaaatag tagtttgatt ggcttcggct tatttaattg gctcagtcct tcaaatctct
    24121 ctatcttaca taatctaaca accttgcgca ttgtcctgcg tagcctgtct attaaaaata
    24181 gatagatgag agttattaac agcaaaaagg agttaccttt ctcgaggtta actcctttgt
    24241 ttatagataa atgttgaata gtttagtaag tcaatacaaa gtattttttc ttcccacgac
    24301 ggataacagt cagttcattc tctaacttat cagcgtcact caagacatag tcaagctctt
    24361 ggatgcggtc gccgtttacg tagatggctc cgttttggac gtcttcacgg gcttggcgtt
    24421 ttgagttaac tataccagat gagacgagca gttccacgat attgttgttt tcgtctgcct
    24481 gtacttggta gtttggcaca ccacgaagtc cttgtttgag ctctttgaca gaaaggtttt
    24541 tgatgtttcc tgcaaagagt tgctcagtga tgttaagtgc ttctttgtag gcttcttctc
    24601 cgtgaacaag tgtaacaact tcacgagcca agactttttg agccaagcgt tcgtgtggcg
    24661 ctgcttcaaa ttgtttacga atatcttcaa tctcatcaag tgacaagaaa gtaaagattt
    24721 tcaagaagcg aacagcgtca gcgtccatca cgttcatcca gaattggtac atttcgtatg
    24781 gagaagtctt ttcgggattg agccagacgg catttccttc tgatttacca aatttcttac
    24841 cagttgcatc tgtgattagt ggaacagtga taacgtgacc agtcttgtcc gccttacgac
    24901 gaagcaattc ggtaccagct gtcatatttc cccactggtc agaaccaccg atttgaagag
    24961 tgacattatg gtcttggtta aggacgaaga agtcataccc ttgcatgatt tggtaagcga
    25021 actcagtgta agaaattcct gtttcgatcc gttttttaac agattcctta ctcatcatgt
    25081 agttgaccgt gaagtatttt ccaatatcac ggaggaagtc aatgaagctg atgctgccaa
    25141 accagtcgta gttgttgacc atgacagcct tgttttcgcc attttcaaag tcaagaaaac
    25201 gagaaagttg tccttggata gacttgaccc agccatctac tgtgtctttt gtttggagac
    25261 tacgttcagc atctttgaag gacggatctc cgatgagacc tgtagcaccg ccaacgagcg
    25321 cataaggttt gtgacctgct agttgcaagc gacgacttgt caagattgcg acaaggtggc
    25381 ctaggtgaag gctgtcagca gttggatcgt agccagtata ataagaaact tgaccttctt
    25441 ctagggcttt acgcaaagct tcttcatcag tcgtttgaaa tatcaaacca cgctctttta
    25501 gctcatcaaa aatgtgcatg tgttttttct cctttttaaa attattgttt ctacctattg
    25561 tatcacaaac ttgggcaata gcctagcaga atagggaaga aagtggctat tttattgaaa
    25621 atttcccttt tgtggtataa tagataaagt gaggaaatcc atgcaaaatc aattaaatga
    25681 attaaaacga aaaatgctgg aatttttcca gcaaaaacaa aaaaataaaa aatcagctag
    25741 acctggcaag aaaggttcaa gtaccaaaaa atctaaaacc ttagataagt cagccatttt
    25801 cccagctatt ttactgagta taaaagcctt atttaactta ctctttgtac tcggttttct
    25861 aggaggaatg ttgggagctg ggattgcttt ggggtacgga gtggccttat ttgacaaggt
    25921 tcgggtgcct cagacagaag aattggtgaa tcaggtcaag gacatctctt ctatttcaga
    25981 gattacctat tcggacggga cggtgattgc ttccatagag agtgatttgt tgcgcacttc
    26041 tatctcatct gagcaaattt cggaaaatct gaagaaggct atcattgcga cagaagatga
    26101 acactttaaa gaacataagg gtgtagtacc caaggcggtg attcgtgcga ccttggggaa
    26161 atttgtaggt ttgggttcct ctagtggggg ttcaaccttg acccagcaac taattaaaca
    26221 gcaggtggtt ggggatgcgc cgaccttggc tcgtaaggcg gcagagattg tggatgctct
    26281 tgccttggaa cgcgccatga ataaagatga gattttaacg acctatctca atgtggctcc
    26341 ctttggccga aataataagg gacagaatat tgcaggggct cggcaagcag ctgagggaat
    26401 tttcggtgta gatgccagtc agttgactgt tcctcaagca gcatttttag caggacttcc
    26461 acagagtccc attacttact ctccttatga aaatactggg gagttgaaga gtgatgaaga
    26521 cctagaaatt ggcttaagac gggctaaggc agttctttac agtatgtatc gtacaggtgc
    26581 attaagcaaa gacgagtatt ctcagtacaa ggattatgac cttaaacagg actttttacc
    26641 atcgggcacg gttacaggaa tttcacgaga ctatttatac tttacaactt tggcagaagc
    26701 tcaagaacgt atgtatgact atctagctca gagagacaat gtctccgcta aggagttgaa
    26761 aaatgaggca actcagaagt tttatcgaga tttggcagcc aaggaaattg aaaatggtgg
    26821 ttataagatt actactacca tagatcagaa aattcattct gccatgcaaa gtgcggttgc
    26881 tgattatggc tatcttttag acgatggaac aggtcgtgta gaagtaggga atgtcttgat
    26941 ggacaaccaa acaggtgcta ttctaggctt tgtaggtggt cgtaattatc aagaaaatca
    27001 aaataatcat gcctttgata ccaaacgttc gccagcttct actaccaagc ccttgctggc
    27061 ctacggtatt gctattgacc agggcttgat gggaagtgaa acgattctat ctaactatcc
    27121 aacaaacttt gctaatggca atccgattat gtatgctaat agcaagggaa caggaatgat
    27181 gaccttggga gaagctctga actattcatg gaatatccct gcttactgga cctatcgtat
    27241 gctccgtgaa aagggtgttg atgtcaaggg ttatatggaa aagatgggtt acgagattcc
    27301 tgagtacggt attgagagct tgccaatggg tggtggtatt gaagtcacag ttgcccagca
    27361 taccaatggc tatcagacct tagctaataa tggagtttat catcagaagc atgtgatttc
    27421 aaagattgaa gcagcagatg gtagagtggt gtatgagtat caggataaac cggttcaagt
    27481 ctattcaaaa gctactgcga cgattatgca gggattgcta cgagaagttc tatcctctcg
    27541 tgtgacaaca accttcaagt ctaacctgac ttctttaaat cctactctgg ctaatgcaga
    27601 ttggattggg aagactggta caaccaacca agacgaaaat atgtggctca tgctttcgac
    27661 acctagatta accctaggtg gctggattgg gcatgatgat aatcattcat tgtcacgtag
    27721 agcaggttat tctaataact ctaattacat ggctcatctg gtaaatgcga ttcagcaagc
    27781 ttccccaagc atttggggga acgagcgctt tgctttagat cctagtgtag tgaaatcgga
    27841 agtcttgaaa tcaacaggtc aaaaaccagg gaaggtttct gttgaaggaa aagaggtaga
    27901 agtcacaggt tcgactgtta ccagctattg ggctaataag tcaggagcgc cagcgacaag
    27961 ttatcgcttt gctattggcg gaagtgatgc ggattatcag aatgcttggt ctagtattgt
    28021 ggggagtcta ccaactccat ccagctccag cagttcaagt agtagttcta gcgatagcag
    28081 taactcaagt actacacgac cttcttcttc aagggcgaga cgataattct ctaaatgaag
    28141 tggccaatca atggattgcc acttttttct tttcgtgtta caataagggt atgaatcagt
    28201 atcagaaaaa gattgttaac ggaaaaattt attcgctcct atccggctta atatggggaa
    28261 tctgtggaat tttaggagag tacttcttta ctcattatca ggtgtcttcg ggctggatta
    28321 cctctatgcg tttgacactg gcagggagtc ttgtactcat ttggtctgca atacaattaa
    28381 aatcgcaagt gctagatatt tggcgagaca agaaaaatta cctgcccttt ttagcctatg
    28441 ctattttggg gattttttca gttcagtatt ttttctatct ctgtgtagaa tactcaaatg
    28501 ctacgacagc aactatttta cagtttatta gccctgtctt tatcctcttt tacaatcgct
    28561 tggtttatca aaaacgagcg tcaaaaagcg ctgttttcta tgttttggtt gccatgctgg
    28621 gtgtttgctt gatggcgaca aagggagacc tctctcagtt atccatgacg ccgctagctc
    28681 ttataacagg tttgctgagt gccatgggtg ttatgtttaa tgttatcttg ccccaacctt
    28741 ttgctaagcg ttatggtttt gttcctacgg ttgggtgggg gatgattttg gcaggtttgt
    28801 ttagcaatgt cctctcgccg gtttatcagc tttcctttac tcttgatatt tggagtatct
    28861 tgatttgcct cattatcgct ttctttggaa cggcttttgc ttttttcatt tccatgaagg
    28921 ctgtgtcctt ggtttctcct ttggtggttg ccgttatcag tgccagtgaa cctctctctt
    28981 ctgctctctt gagtgttttg ttcttaggat tagtagtgga ttggtccctc cttctagcta
    29041 tagccttgat tattttaccc atgatatttt tgtctataga agaagcgaaa gaaagtagat
    29101 aaaaagtctt ttcttaattc taaaagtgtg ctatactaga atagtcaata aaacacgggg
    29161 agatagttgt gaagagtgtt tttaggttgt atcggtaggg gcttgctttt accgacagca
    29221 cgttttatct cacatcccta aaaaatcata cctaaaaaca gacaaaaagg tttcaaattt
    29281 gaggcctttt ttggtagaat aggtatcatt ataacgaacc aggaggcacc tatgactgct
    29341 acaaaaatga acgctcaaga aattatccaa tttatcgcca atgctgaaaa gaaaaccagt
    29401 gtcaaagtaa cctttgaggg gcaactcgca actgctgtgc ctagctctgt tgtcaaacta
    29461 ggaaatgtcc tattcggaga ctggaaggac gtggctccgc ttcttgaagg tttggtagaa
    29521 aatcaagatt atgttgtcga gcaagatgct cgtaattctg cagttccttt gctagataag
    29581 cgtgctatca acgctcgtat cgagccaggt gctattatcc gtgaccaggt ggaaattggt
    29641 gacaatgctg ttatcatgat gggagctgtt atcaatatcg gtgctgaaat cggtgctgga
    29701 accatgattg acatgggtgc catccttggt ggccgtgcca tcgttggaaa aaatagccac
    29761 gttggtgcag gtgcagtttt ggcaggtgtg attgagccag ctagtgctga accagtccgt
    29821 gtcggagaca atgttctcat cggggctaat gcagtggtta tcgaaggagt ccaaatcggt
    29881 agtggttcag ttgtcgcagc aggagctatt gttacccaag atgtcccaga aaacgtggta
    29941 gtagcaggtg ttccagctcg tattatcaaa gaaattgatg cccaaactca acaaaaaaca
    30001 gcgctagagg atgcgcttcg taccttgtaa ttgtaaaagt aaaaaagagg cggaaccctt
    30061 tttccagcct ctttctgcta tatcggagga cagatagatg ttagatttga ttcagactag
    30121 acgagattta caccagattc cagagattgg cttggaggag ttcaagactc aggcttattt
    30181 gctggatgtg attgagaaat tgactacggg caaggatttt gttcaaattc gtacttggcg
    30241 gacagggatt ttggtctacc tgcagggaag tcagccggag cgaaccattg gttggcggac
    30301 agatattgat ggcctgccta tcgtcgaaca aacaggtcta ccttttgctt ctcaacacca
    30361 aggtcgcatg catgcctgtg gccatgattt tcatatgacc attgccttag gctgtcttga
    30421 gcgcgccctt gaggagcaac ccaagaataa tctgctcttt ctatttcagc ctgctgaaga
    30481 aaatgaagct ggtggtatgc tcatgtatga ggacgatgct tttggagatt ggttgccaga
    30541 tcaattttat ggcctccatg tccgtccaga tttgaaagtc ggccagattg cgactaatac
    30601 tcatacactc tttgcaggaa cttgcgaggt gaagatccgt ttcaaaggca aaggtggcca
    30661 cgcagctttt cctcatgaag ccaatgacgc cttggtggcg gctagttact ttgtgaccca
    30721 agtgcagtca gttgttagcc gcaatgtcaa cccaatcgag ggagcagtgg tgaccttcgg
    30781 cgtttttcaa gctggaacca ccaacaatgt catcacagac acagcttttt tacatggaac
    30841 tattcgtgcc ttgacacagg acatgagtct cttggtgcaa aagagggtaa aaacagttgc
    30901 agaaggggtt gcagctgcct ttgatatgga agtcgaagtg gaactcaaac aaggtggata
    30961 cctacctgtt gagaacaatc cagccttggc gcgtgaactg atggacttct ttgacgaaaa
    31021 agacggaatc gagttgattg atatcgaacc tgctatgaca ggcgaggact ttggttatct
    31081 cctttcaaag gttgatggcg tgatgttttg gctaggtatc gatagtccct acgctcttca
    31141 tcaccctcaa atgagtccta aggaagaagt cttagctatt ggggtggctg cggtgtctag
    31201 tttcctgaaa aagaaggcag cagaatagag ggcttgtcta tgaaatcgga attacgcaag
    31261 caagtcttgc atgaaatgaa ggctatatct caagagcaaa aacaggctat agaccaagct
    31321 ttaaccgagc gaattttaca acaccccttt tatcaagaag ccaaggtcat cgcaacctac
    31381 ctctcttttt ctcatgagtt tcaaacgcgg gaactgattg agcaggcgct gaaggacggc
    31441 aagaaggttt taatacccaa aacttatccc aaggggcgca tggactttgt agtctatgat
    31501 ccgcagcagt tggtaaaaac tgcctttgcc ttactggagc cacagggaga tttggaagtg
    31561 gtggatgcat ctcagattga tttgattcat gttcctggcc tggcttttac gacggatgga
    31621 tatcggattg gatatggtgg aggttattat gaccgctatc tggaacattt ttctggtcat
    31681 actttgagta cggttcatcc ttgtcaaatt caggacttta tacctgaaaa ccatgatatt
    31741 cctgttcagg aggtattaat tgatgaagga aatctttgat agacgttacc ctgtgacgag
    31801 tttcttcctc ttagtgacgg ccttggtatt tttactaatg ttggtcactg caggcggaaa
    31861 ctttgacagg gcagatacat tatttcgatt tggagccatg tatgggccag ctattcgcct
    31921 ctttcccgag caggtttggc gtctcttgtc tgccattttt gttcatattg ggtgggaaca
    31981 tttcattgtt aatatgcttt cactttatta tcttggaagg caggtagagg agattttcgg
    32041 ttctaagcag tttttctttc tctatctttt atcaggaatg atgggcaatc tctttgtttt
    32101 tgtatttagt cctaaatcct tagcagcagg cgcctctacc tctctttatg ggctatttgc
    32161 cgcgattatt gttcttcgct atgcaactcg caatccttat atccaacagc tagggcaatc
    32221 ctatctgaca ctttttgtgg ttaacattat tggaagtgtt ctgattccag gaatcagcct
    32281 agcaggccat atcggtggtg cagttggtgg cgcatttcta gcagttatct ttccagttag
    32341 aggagaaaaa cggatgtata acaccagcca gagattagga gcggtagtct tgttcgtagg
    32401 actcgccatt ttgcttttct acaagggaat gggaatgtga cgaagttgaa agaaaatttg
    32461 tgtaatgaaa aaagataagg cattttttga accttatctt tttattttat tttattcctt
    32521 ctcagtcaat tcttttccaa gttggatgag gtaattcttc aaatcatctt tgacttgtgg
    32581 gtgtttgagg gcgtagtcga tggatgtttt catgaagcca aacttgtctc cgacatcgta
    32641 acgagcccca ttgaactcac gagcaaatac acgttgtgtt ttattgaggg tgtcgattgc
    32701 atctgtcagc tgaatttcat ttcctgcacc tggagcttgg ttttcgagga tttggaaaat
    32761 ttcaggcgtg aggaggtagc gtccgataat agcaaggtcg ctaggagcgt cctctggagc
    32821 tggtttttca acaaaggttt caacactgta aagaccatct tttccttcgc cttgcggagc
    32881 aataaccccg taagcagata cttcgtcatg agggactggc atgacagcga tagtagacgc
    32941 gtgggtacgc tcgtagtcat ccatgagttg tttggtaagt ggaacagcct tttcgtctgt
    33001 gatatccatc aagtcatcac caagcataac gacaaaaggt tcatttccga cgaaagcctt
    33061 ggcttgcaaa acagcatctc cgagaccgcg tggatgagtt tggcggataa aatgcagccg
    33121 catgtcagtt gttttatcaa ctagcttcaa aagatctgtt ttcccttttt ctttgaggtt
    33181 atattccaat tcgaagtttg aatcgaagtg gtcctcaata gaacgttttg atttaccagt
    33241 gacaactaga atatcttcaa tacctgattt gagagcctct tccacgataa actggatagt
    33301 tggtttgtct acgattggca acatttcttt ggcaagggcc ttggttgctg gtaaaaatcg
    33361 agttcctagt ccagcagcag ggataactgc ctttctaact tttgatgtca taaaaatcct
    33421 ttctatagag ggttaagacc actcattttc tgctttaaat tcattgttca tgatgtcata
    33481 aatggcatct ttgatattgg ttccgtgata aataacttgg taaatagcct gtgtaatggg
    33541 catatagact ccaagttctt gggctagttc ataggctgct cgagtcgttg aaattccttc
    33601 gattaccatg cccatattag cttctatatc agctagggat tctcctcgtc cgagagcatc
    33661 tccagctctc cagttacgag agtggatgga agttcccgtt acgatcaaat ctcccacacc
    33721 agataagccg ctataggtca atggactggc cccgagtgct acccctaggc gggtgatttc
    33781 tgctaaacct cgagcgatga tggctgcctt agcattatca ccaaatccaa gaccatgtaa
    33841 agctccagca ccgacagcaa taatattttt aagagcacca gcagtttcaa ccccgataac
    33901 atccgtattg gtataaagtc ggaagtagtg attactaaat agctcctgaa cgtattgagc
    33961 tgtttgtaaa tctttagaag cagcagttat taaagttagg tcacgcacaa tggtctcttc
    34021 tgcatgacta ggccctgaaa caacgacgat atcactacgg agatgttcag gaatttcttc
    34081 ttcaagaatg gttgataatc gtttatggct atcaggttct aatccctttg atgcgtgcat
    34141 gatgataacc ttatggtcca aggtttgtgc aacttgctgg gcaacaagtc gtgtcacttt
    34201 tgttgggaca acaaacaaaa tcgcatccac atttttcaat gtttctgcta agtcggtgta
    34261 ggcaatgata ttttcgtcta gaacgacatc tttaaagtag tgcttattag tatggtgtgt
    34321 attaatttca ttgatttgct cgggaagatt tccccaaata cgtacctcgt gtccattgtc
    34381 atttaagact tgtgaaaggg cggttcccca agaaccaggc cccaagacgg cgacggtttg
    34441 tttttccatg atttcctcct tgatagattt ctttctctta ttctatcata ttctagggga
    34501 ttttgcactt gcattactgg ggtatggtgg aaaaatacac aaagaccgag atgaagggat
    34561 aaactcttag tctttagtta aagtgagaag aaatctgata gatagtttga ttcagtatat
    34621 gcttataata gaggtaaaca actcaggaag ttcttgtagg ttgcgagagt ttggcgaaaa
    34681 aattaaaaga ttacgtttgg ctaaaaaaat cagtcgttca gaattttgtg gtgatgagtc
    34741 tgaattaagt atccgtcaat taattagaat tgaaaatgga gaatccagac caacactaac
    34801 aaagttaaaa tatattgctg aacgtttgga ggttgaagat tacaagttga tgccaagtta
    34861 tatagagttg gataaggaat acctagaatt gaagtatttc ttgatgagga ctcctacata
    34921 cgaagatgaa actatcgccc aaaagaaaga gagtgttttt gataagattt ttgaagagta
    34981 ttatgatagg ctacctgagg aagaaagatt tatcatccca aattattcat atctagcact
    35041 agcgaactac acagttcaaa aattaccaga aaagctagtt gaaatactgt ccttctggtg
    35101 attttgctta atttctgatg ttcgagacat gattgaggag atttgtcttg attttttcct
    35161 aaaaaagggc agactcctcc cttggtttga tgctcgattt ttaaaataag gtgacttatt
    35221 ctgttaggca gttttcccct gccctctagc tctatatgga acagggagta tcagatttat
    35281 ctggcagatt gtatcaaata aggcttgaaa ctgttttgaa taggcgtata gacttgagaa
    35341 tttgagaata tgtcgtctag cagtagagac atattttccg gcaatatgaa ggaagagacg
    35401 tcgaaaacgc ttgatagtca aggcctttac ttcatcacca gctagctgct ttaaaaagag
    35461 gtagagatta taagccagac agcccatcat catacgtact tcattcttaa tcatggtcga
    35521 actatctgtc ttatccccaa agaatcctgc tttcctttct ttgataaagt tttcagcatt
    35581 ccctcgttca cgatagaatt gaaacagctc ctcactatct acactgctta aattggtcaa
    35641 atgaactttt ttacaaccat aaaaaagagc acttaatcgt actcttctct tttaaggatt
    35701 agttgaatta attcaaatcc actagttctc ctgtttctag gtagactagg cgttcacaaa
    35761 tgttagcaat gtaatcagcg aagcgttcca gatgccctat gatataaagg tattgagttc
    35821 cattgggaat tgaggtttct tggtctttca taagtccaat gatttccttt gataaggcat
    35881 aataatattg gtcaatctgt tcatcttttt gagcaatact aatagctttt gaggcttggt
    35941 gcaaaggaaa ggcaaccaat aaatcggcta gcatgctgag ggataattta cccatttggt
    36001 gtaactgttc ttcgtcaggg gctagttgat tttcttttag ttgcaaaaca gctttggcaa
    36061 tgcctgccat atggtctccc atacgttcaa ggtctgaaca agaagacatg atgctaatca
    36121 caaatcgaag gtcagacact tgtggctgct gcaaggccaa caaacgggca caggtcaatt
    36181 cgatagcgct ttgaccttgg tttatagcat gatccttatt gataattagc tctgccatct
    36241 ccttgtcttt ggaggctaag gccagtaagg cttttgaagc tgtttcaagg acaagttgcc
    36301 ctagtcctaa aaaggattgt tctaattcat gcaattctaa gtcaaattga tttctcatag
    36361 gtttttcctt ccttatccga accgtcctga aatatagtct tctgtgcgct gatcttttgg
    36421 attggtaaac acgtcaacgg tatctccaaa ttcgcaaatt tctcctgtta agaaaaaagc
    36481 agttttatct gaaatacgtg aagcttgttg catgttatgg gtaacaatga taatcgtata
    36541 atcctttttt agttgctgaa tgaggtcttc aatttttaaa gtggagatag ggtctaaggc
    36601 tgaagtcggc tcatccatta acagaatatc aggttctact gctaaagctc gcgcaatgca
    36661 aaggcgttgc tgctgaccgc cagataagga catggcactc tttttaagat catctttgac
    36721 ttcttcccaa atggctgccc cttttaaaga tttctccact aaggcatcta attgtttttt
    36781 gtctcgaata ccatgtgtcc ttgggccata agccacgtta tcatagatag acatggcaaa
    36841 gggattaggc tgttgaaaaa ccatccctac acgcttacgt agctgattaa ggttgaattt
    36901 gctactataa atatcttgct catctaagag gacttggcct tcaatatggc aagaaggaac
    36961 caaatcgttc atccggttaa gggtttttag aaaagttgat ttgccacaac cagatgggcc
    37021 tatcaaggca gtaatctgtc tttctggtaa ttgaatcgaa atatttttta aggcttgaaa
    37081 atccccgtaa aataagtcta ggtgtctgac tgaaaatgtt cccatactag gaagctcctt
    37141 tcacaagttt tcgagataat aagcttgata gagtatttat cattaaaaca gtaataatca
    37201 aaatcacacc ggtagcatag gcttcattga catgtagccc ctcacttgac agcatataca
    37261 tatgcagggc tagagaacga cctgaagaca tgagactact tggcgtattg gtagaggtac
    37321 ctaatgtata catgagggca gctgtctcac caacgatacg gccaatagct agtatcactc
    37381 cagctaaaat acctggcatg gcaactggta gaacaattct aaaaacagtc cgtaacttac
    37441 ctgccccaag tccataactt gcttgacgca tgctatcact aacagataaa agggcttctt
    37501 ctgttgagcg aataatgact ggcaacacca tgatgactga ggttaagatt cctgataaca
    37561 gagagtattg aaaacctaag aagactacaa agaagagcat gccaaacaga ccaaaaacaa
    37621 tggaaggaat cccagacaag gtatctgagg ccaatcgcat gattttaaca caaagggaat
    37681 ctttttttgt atattccaca agataaaaac cagcaaaaat ccctatgggc aaggctaaaa
    37741 gaagagcacc aaagaccaga ataacggtgg aaataatcgc tggcataagg gaaatgttct
    37801 cagaagtata agtccaagaa aagagggata gacttagatg aggtaaacct ttgatgagga
    37861 taaaaccaat gattaaaaag agagagccaa aggttaaagc tgaaaaacaa taaacgagaa
    37921 gttttagcag gtatttactc ataagatgat tttcctttca agtaggcaaa gtaggcatta
    37981 atcaagagaa taaggaaaaa gagaactgct gaggttgcaa taagggcttc cctatgctga
    38041 cctgatgcgt aagccatttc cagaacaata ttggttgtta aggttctggt tcctgaaaag
    38101 agtccacttg gaataatcgg ctggttgcct gccaccaaaa taactgccat ggtttcacct
    38161 actgcgcgac cgatgcctaa aataactgct gataaaatac cagatctcgc agctggcaag
    38221 atgacactaa aaatactccg ttcatgacta gctcctagag ccaagctacc agaataatac
    38281 gttttgggaa ctgttcggat agcagattct gacaaactga taatggttgg caaaatcatt
    38341 attcctaata gtaacgaagc ggttaggaca ctcatgccat ttcctaaaaa gcttctaatc
    38401 caaggcacca ataattgtag gccgaaaaaa ccataaacaa tagatggaat ggccgccatc
    38461 aagttgatag ctgattttaa gaagccatag acgggctttg gacaataata aaccataaac
    38521 accgatgtca agatgcctgt tggcacccca atcacaatcg ctcctaaggt aattaataag
    38581 gaaccaacga tcattggtaa aataccatag cttgccggaa tgttcgttgg cgaccaatca
    38641 ctgcctaata aaaaacgggc aaagccgtag ttagccatga aaggtaagcc attactaaaa
    38701 ataaagaaac agattagcaa aatagctaca acagctactg ttgcactcat gaaaaaaatt
    38761 gccctaaaaa ctgcttcttt gaaggcttgt tttatcacat cttgtccttt ctagtgaaga
    38821 aagtaaggga gatacgacac ctccctactt gccttcttta tcttattgta cgatgaaacg
    38881 tctgcatctc tttagagatt tatggagcaa acattttatt taatcttgtc ccaggtggtt
    38941 aatttgccac taaaaacgtc tgcaagttca gccatactga cttggcttgc cttattgtca
    39001 ttattgacca caacagcaat accgtctaaa gcaatagcat catgggtgag actcttacct
    39061 tcttcaggag ttaattccct agaaaccata ccaatatcag cggttttctc cttaacagcg
    39121 gtaatacctg ctgaagaccc attagaggta atatcaatcg taacttctgg attttctttt
    39181 ttataagctt ctgctaattt ttccattaaa gaagatactg aagtggaacc tacaacagac
    39241 aacttgcctg ataagtgttg gcttgtatat tctgtggttt cagttttagc ttcaataaat
    39301 ttattatctg tgaccacttg ttgaccttgt ttggagtgga taaagctgat aaaatcttga
    39361 cctagcttgg aaagattaga agaccaaaca atgttgaagg gacgttgaag agggtattca
    39421 ccatctaaaa ctgtgtctcg actagccttg acaccatcaa tctctaaagc cttgacagat
    39481 ttcgttaaag atcccaagga gatgtagccg atagcattag cattcccttg aactgctgag
    39541 agaacacctt ctgtactatt ttgaatcaca gctgttttgg cagtgttgtc aattttttta
    39601 tcaccgtctt ttttgagaat ccctgtgatt tctgtgaagg caccccgtgt tccagagcca
    39661 ttttctcgtg aaatcacctc aatcgttcct gaagctgact gtttggaagc agctgactga
    39721 ttgccacagg caacaagccc aaatcctgat aagccaatgg ctgcaagagt aagcattttt
    39781 ttgaatttca taataatcac ctttatctct atgtattttt cttgtgtagg cttactacat
    39841 ttatagtcta acaagtcttt gtaaaggttt atccctgatt catgtaaaga ttgtgtaaag
    39901 aatcaaaaaa agccactttt gaaaaatggc tgctcctaaa aatagcttta aaaattatta
    39961 gtcctgtgcg aaagattggt taggaagaaa aatcgtgaag caactgcctc tgccaagctg
    40021 actcgtcacc gtgacttggc cacctaataa ttgactgagt tctttgacaa tggcaaggcc
    40081 aagaccagtg ccaccagttt gtctgcttcg acctttatta actcggtaaa aacgttcaaa
    40141 aatacgatcc tgctctaatt gactaatacc aatccctgta tctgatacag aaatcttaat
    40201 gccttcgttc accttttggg tcttgacctc aatttttccc ccttgttcag tgtaacggat
    40261 ggcattggat aaaagattga gtaagatttg ggaaagtaat tgactatctg atacgagggt
    40321 gacatcatct ggcacctgca cctttagctg taaatccttc ttcttgagct gaggttgcaa
    40381 gctttgagtc aaatcctgta caaattcagc caaagaaagg gtcgtccatt gtataggcat
    40441 ttgttgagcc ttagataagg taagaagatg ctcaacaata tgctcaagac gcaaactttc
    40501 tttgtaaata atgtctagaa agtcatcctt gagcgcttct tcttcagctg acatcccctt
    40561 aatggtttca gcaaagccct taattgaagt aactggtgtc ctcaattcat gggaggcatt
    40621 tgagacaaag gctaaattta acttttcata agttctaatc gttgttaaat catatagcaa
    40681 gacgagcaca gcttccacag attgggtggg gctaaaaacg ggaactgctg tcacttctaa
    40741 aatcaagtca ccctcatgaa acccacttac ttcttgtttt aaccttgttt tttgatcaaa
    40801 ggcttggtga actaaattcc gaatatccat ccgtttgagg tcatcaagtg aacttatgtc
    40861 gccgtccaca tcgggaaaat aatgaggcag agagcgactg gataataaca tctgaccttg
    40921 agcggaaact aaaaacgtcc ccatggttag gtgcgacaga agaacctcca ttgtttcggc
    40981 taggtccttg tattgctgat cctgttggga gactttggtt tttaggccag acacatactg
    41041 agccaaagac tttaagtctt cttgcccttt ttctaaaaag tattcactac tggtcaagag
    41101 aggttggtgc aaggtctcaa aagcaacttc ccatttccaa aggcaaaaga gccagtagcc
    41161 accttgtccc aaagaaaggg ctagaagaaa gagaccgatg cctttactga tccaagttaa
    41221 tgccatccct gcaatcagaa tgaggctaac acttagattg actagccaaa attgaaggta
    41281 gcgtttcatc tataactcct tgaacttata accataaccc cgaatggttc gaataaattg
    41341 aggggcttta ggattgtctt caattttttc cctcaactta ccaatatgaa cgtccaccaa
    41401 acgtgtttcc tgcccaaagt cataccccca gatacgttcc aaaagacgct ctctagtcag
    41461 tgtcatgttg ggatgtttca taagatagag caagagttca aattcttttg gggtcaaact
    41521 cagtaactta ttcgccttgt agacttcatg acgctcaggg tatactttca aggtcccaaa
    41581 tagccaagaa tcgtcagcga tattatctga atcatctcct tcttgttctc ctttagttcg
    41641 cctgaggaca gccttgacac gcgccagcaa ttctctaggg ctaaaaggct tggtcaggta
    41701 gtcatcagcc cctaattcca aggccaaaac cttatcaaat tcatcacttt tcgcagaaac
    41761 catcataatt ggagttttga cgcctttggc tctcagccgc ttacaaactt ccatgccatc
    41821 taattgtggt aacatgatat caagcaagat aaaatcaaag ggttctgttt ctgccaaagc
    41881 taaggccttc cgtccatttg ttaccaattg agtagaaaag ccttccttac ttaaatggta
    41941 gtcaagcaat ttcagaatgt gttcttcatc atccactaat aagacttgtt ttgtcatcta
    42001 ttatctccta ttggtaacat tataacacaa ttatcagaaa tcctaacatt gctaaatcag
    42061 attaaatttg cttatcaaga ctagtatctg gtcaaacgct caatcatctc cttgtgctct
    42121 ggataggtcg ccagtagatc taccctttca aataattcaa aatcctcaaa ttcaaaacca
    42181 ggagcaacaa gacaagaaac cagagcataa tccttatcaa ctgttgatcc ccaaatagtg
    42241 cccttaggaa cacagtagtg aagttgttgc cctttggata tgtccaggcc taaagtgact
    42301 gcttcgtagt gaccatctgc tgtaatcatg tgaacagtaa gtggggatcc tgcatgaaaa
    42361 taccagattt catctgctgt caatcggtga aaatgtgaag gattcgtttc ttctaataag
    42421 aaataaatac tggtataaag cgcccttccc ttaccagcaa ggtttatagt gtctgaagct
    42481 ttttttgttt gtctaaaata gccaccttca acatggggag ctaactctag agttcttatc
    42541 aagtcttctt tatccatcgg ggccaatggg ttgaagtaac tcttgttcaa agtggtttta
    42601 cgatttcaag aactcctctc agttctgagg acacggtaat gattgatgcg acggaagtac
    42661 aaatcaatcg ccctaaaaaa agaattagcg aatgattctg gtaaaaagaa atttcacgct
    42721 atgaaggctc aagcgattgt cacaagtcaa gggagaattg tttctattgc catgatatga
    42781 agttgttcaa aatgagttgc agaaatatcg gacaagctgg taaaatcttg gctgacagtg
    42841 attatcaagg gctcatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac
    42901 tcaagccgct aacagctgaa gataaagcct ataaccatgc gctatctaag gaaagaagca
    42961 aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat attttcaaca acctatcgaa
    43021 atcatcgtaa acgcttcgga ttacgaatga atttgattgc tggtattatc aatcatgaac
    43081 taggattcta gttttgcagg aagtctatta tttggttagg tgaattagtg aagtgtttag
    43141 gcaagtgtct ctggttacga cgtcatggcc tctaaatcga ttatatttag gggtcatgac
    43201 tagtgaagca gttagctagt tcgcatataa gcggctagcg tctaacaatt aggaacttta
    43261 gttccaataa ctttaagatt acgacgtttt aggacataaa tcgatcatat ttatgtccta
    43321 aaactagtga agcgcctagc caaagtccga ataggatttg gcgttagtta cttagattgc
    43381 tttgcaatca agtaactttg gcgatttaca tcttctctgg cgcttctact ccaagcaagc
    43441 gaagggcttc tttgagaacg actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt
    43501 ctgggctttc atccaagata cgtgtatgtg catagtattt gttaaaggat tgagccaggc
    43561 taattgcaaa tttagcaatg atagaaggtt caaagttatc tgccgcacgg ttgataatac
    43621 gtgggaagtc ttgaatgagt ttaatgattt cccagctttc agtatcattc aagctatagt
    43681 tgccagctgt ttctggtttg aaatcggctt tgcgtaagat agattggata cgagcgtagg
    43741 catattgaac gtaaggtcca gtttcaccct cgaaggatac catagcttct aggtcgaagt
    43801 cgtatccatt tgtacggtca gttttgaggt catagaattt aatggctcca accccaacag
    43861 catgtgctac ttggtctttg ttttctagtt caggattttt agcctcgatt tggaccttgg
    43921 cacggctaac agcctctgca acagtaggct ctagcaagat gacattccct ttacgagtag
    43981 agagcttctt cccttctttt gtaaccagac caaaaggaac gtgggtaatg tcgtcactcc
    44041 aatcgtagcc catctcttgc aagacagctt tgagttgttt aaagtgggca gattgctctt
    44101 gaccaacgac gtagatagat ttagcaaatt ggtattcatt tttacggtag agggctgcag
    44161 ccaagtcacg tgtgatatag agagttgcac catcagactt cttgatgagg gctggatgtt
    44221 caattccata tttctcaaga ttcacaactt gggcaccttc tgattcaaga agtagtcctt
    44281 tttcagaaag aatgtctaca actgcatcca tcttatcatt gtagaaggct tctccgttat
    44341 agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt aaattccact aaactttcat
    44401 cgcggaacca ttgccaaaga gcgagagctt cctcatctcc attttcaagt ttacggaacc
    44461 attcgcgcgc ttcttcatcc aagctagggt cattttcagc ttcagcgttg atgcggacat
    44521 agagtttaag gagttcatcg attggatgag cttttacagc ttcttcgtcg ccccattttt
    44581 tgtaggcaac aatcaacatc ccaaattgtt taccccagtc tcccaaatgg ttgaccttga
    44641 ccgtttgata accgattttt tggaaaatat gtgacaagct atctccgata acagttgaac
    44701 gcaggtggcc aatagaaaat ggtttagcga tattcggact agacatgtcg ataacaacat
    44761 tttcttgttt gccaatattt tggtcagcat agtgttcttt ttcagtggta acagcttgca
    44821 atacttgagc agaaatggca gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga
    44881 caactttttc aaaggcttgg ctgttcattt tttcagccag ttcagccgca atcatttgtg
    44941 gtgctttacg ttcgactttg gcaagagaaa aagcagggaa agcaatgtct cccatttctg
    45001 agtttttagg ggtttccagt aactttaaaa tagcctcttg gtccaggcta tcaatgatgc
    45061 tagataattc gctagcaatc aattcttttg tattcattaa gagctccttt ttggactttt
    45121 ctactatttt atcacaattt taaagaaaga agaaaaaatt tttgaaatct cctgtttttt
    45181 tggtataata tggttataaa tatagttata aatatgcacg caagaggatt ttatgagaaa
    45241 aagagatcgt catcagttaa taaaaaaaat gattactgag gagaaattaa gtacacaaaa
    45301 agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg
    45361 tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat gatatggtgt attatgtact
    45421 agtaaatgag acagaaaaga ttgatttggt ggaatttttg tctcatcatt tagaaggtgt
    45481 tgcaagagca gagtttacct tggtgcttca taccaaattg ggagaagcct ctgttttggc
    45541 aaatattgta gatgtaaaca aggatgaatg gattttagga acagttgctg gtgccaatac
    45601 cttattggtt atttgtcgag atcagcacgt tgccaaactc atggaagatc gtttgctaga
    45661 tttgatgaaa gataagtaag gtcttgggag ttgctctcaa gacttatttt tgaaaaggag
    45721 agacagaaaa tggcgataga aaagctatca cccggcatgc aacagtatgt ggatattaaa
    45781 aagcaatatc cagatgcttt tttgctcttt cggatgggtg atttttatga attattttat
    45841 gaggatgcgg tcaatgctgc gcagattctg gaaatttcct taacgagtcg caacaagaat
    45901 gccgacaatc cgatccctat ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat
    45961 gtcttgattg agcagggtta taaggtggct atcgcagagc agatggaaga tcctaaacaa
    46021 gcagttgggg ttgttaaacg agaggttgtt caggtcatta cgccagggac agtggtcgat
    46081 agcagtaagc cggacagtca gaataatttt ttggtttcca tagaccgcga aggcaatcaa
    46141 tttggcctag cttatatgga tttggtgacg ggtgactttt atgtgacagg tcttttggat
    46201 ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc gagaagtggt gttgggttat
    46261 gacttgtctg aggaagaaga acaaatcctc agccgccaga tgaatctggt actctcttat
    46321 gaaaaagaaa gctttgaaga ccttcattta ttggatttgc gattggcaac ggtggagcaa
    46381 acggcatcta gtaagctgct ccagtatgtt catcggactc agatgaggga attgaaccac
    46441 ctcaaacctg ttatccgcta cgaaattaag gatttcttgc agatggatta tgcgaccaag
    46501 gctagtctgg atttggttga gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg
    46561 cttttggatg aaaccaaaac ggctatgggg atgcgtctct tgcgttcttg gattcatcgc
    46621 cccttgattg ataaggaacg aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac
    46681 catttctttg agcgtagtga cttgacagac agtctcaagg gtgtttatga cattgagcgc
    46741 ttggctagtc gtgtttcttt tggtaaaacc aatccaaagg atctcttgca gttggcgact
    46801 accttgtcta gtgtgccacg gattcgtgcg attttagaag ggatggagca acctactcta
    46861 gcctatctca tcgcacaact ggatgcaatc cctgagttgg agagtttgat tagcgcagcg
    46921 attgctcctg aagctcctca tgtgattaca gatgggggaa ttatccggac tggatttgat
    46981 gagactttag acaagtatcg ttgcgttctc agagaaggga ctagctggat tgctgagatt
    47041 gaggctaagg agcgagaaaa ctctggtatc agcacgctca agattgacta caataaaaag
    47101 gatggctact attttcatgt gaccaattcg caactgggaa atgtgccagc ccactttttc
    47161 cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg aagaattagc ccgtatcgag
    47221 ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg aatacgaaat atttatgcgc
    47281 attcgtgaag aggtcggcaa gtacatccag cgtttacaag ctctagccca aggaattgcg
    47341 acggttgatg tcttacagag tctggcggtt gtggctgaaa cccagcattt gattcgacct
    47401 gagtttggtg acgattcaca aattgatatc cggaaagggc gccatgctgt cgttgaaaag
    47461 gttatggggg ctcagaccta tattccaaat acgattcaga tggcagaaga taccagtatt
    47521 caactggtta cagggccaaa catgagtggg aagtctacct atatgcgtca gttagccatg
    47581 acggcggtta tggcccagct gggttcctat gttcctgctg aaagcgccca tttaccgatt
    47641 tttgatgcga tttttacccg tatcggagca gcagatgact tggtttcggg tcagtcaacc
    47701 tttatggtgg agatgatgga ggccaataat gccatttcgc atgcgaccaa gaactctctc
    47761 attctctttg atgaattggg acgtggaact gcaacttatg acgggatggc tcttgctcag
    47821 tccatcatcg aatatatcca tgagcacatc ggagctaaga ccctctttgc gacccactac
    47881 catgagttga ctagtctgga gtctagttta caacacttgg tcaatgtcca cgtggcaact
    47941 ttggagcagg atgggcaggt caccttcctt cacaagattg aaccgggacc agctgataaa
    48001 tcctacggta tccatgttgc caagattgct ggcttgccag cagacctttt agcaagggcg
    48061 gataagattt tgactcagct agagaatcaa ggaacagaga gtcctcctcc catgagacaa
    48121 actagtgctg tcactgaaca gatttcactc tttgataggg cagaagagca tcctatccta
    48181 gcagaattag ctaaactgga tgtgtataat atgacaccta tgcaggttat gaatgtctta
    48241 gtagagttaa aacagaaact ataaaaccaa gactcactag ttaatctagc tgtatcaagg
    48301 agacttcttt gacaattctc cacttttttg ctagaataac atcacacaaa cagaatgaaa
    48361 aggagctgac gcattgtcgc tcccttttgt ctatttttta aggagaaagt atgctgattc
    48421 agaaaataaa aacctacaag tggcaggccc tggcttcgct cctgatgaca ggcttgatgg
    48481 ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt cttaggcgcc ctccttgctg
    48541 ggaaatatga agctatttat agtatcgggg cttggttgat tggtgtggcc gtagtcggtc
    48601 tagttgctgg tggactcaat gttgtcctcg cagcctatat tgcccaagga gtttcatccg
    48661 accttcggga ggatgccttc cgtaaaattc aaaccttttc ttatgctgat attgaacaat
    48721 ttaatgcggg aaatctagtc gttcgaatga caaatgatat caaccagatt cagaacgttg
    48781 tcatgatgac cttccagatt cttttcagac ttcccctctt gttcatcggt tcgtttatcc
    48841 tagcggttca aaccttacct tctctgtggt gggtgattgt tctcatggta gtcttgattt
    48901 ttggtttgac tgctgtcatg atgggaatga tggggcctcg ttttgccaag tttcaaaccc
    48961 ttcttgagcg catcaatgcc attgccaagg aaaatttacg tggcgttcgt gtggtcaagt
    49021 cctttgtcca agaaaaagag caatttgcta agtttacaga ggtctcagac gagcttcttg
    49081 gtcaaaacct ttacattggt tatgcctttt cagtagtgga accctttatg atgttggttg
    49141 gttacggggc ggtcttcctc tctatttggc tggtcgcggg aatggttcag tcggatccgt
    49201 ctgttgttgg ttccatcgct tcttttgtta attacctaag ccagattatc tttaccattg
    49261 ttatggttgg atttttggga aattctgtca gccgtgccat gatttccatg cgtcgtattc
    49321 gagaaattct tgacgcagag ccagctatga ccttcaagga tatcccagat gaagagttgg
    49381 ttggaagcct tagctttgaa aatgtgacct ttacctatcc aatggacaag gaaccgatgc
    49441 tgaaagatgt gagctttact attgaacctg gtcaaatggt tggtgtagtt ggagcgactg
    49501 gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct ctttgatcca caggaagggg
    49561 ctatcaaaat cggaggtaag gatattcgag aagtgagtga aggaaccctg cgtaaaacag
    49621 tttccatcgt tctccaacgt gccattcttt ttagtggaac gattgcagat aacttgagac
    49681 aggggaaggg aaatgctact ctatttgaaa tggagcgcgc agccaatatt gcccaggcta
    49741 gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc agttgaagaa cggggaacca
    49801 atttctctgg tggacaaaaa caaaggatgt cgattgcgcg tgggattgtc agcaatccac
    49861 gtattctgat ttttgatgat tcgacctcag ccttggatgc caaatcagag cgcttggtgc
    49921 aagaagcttt gaataaggac ttgaagggga cgacaaccat tattattgct caaaaaatta
    49981 gctcggttgt ccatgcagac aagatcttgg ttctaaatca aggacgattg attggtcaag
    50041 gcacgcatgc agacttggtt gccaacaatg ccgtttaccg tgaaatctat gaaacacaga
    50101 aatgaaagac aaactataag aaaagtcaat agttttatct aaactatttc ttatttcaat
    50161 ttgatgattt ggcgatgatt ttagagcacg gcaaaaagct
//
LOCUS       DAVKBK010000009        48828 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVKBK010000009 DAVKBK010000000
VERSION     DAVKBK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.009"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(165..515)
                     /locus_tag="VWX69_000566"
     CDS             complement(165..515)
                     /locus_tag="VWX69_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191958.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(655..990)
                     /locus_tag="VWX69_000567"
     CDS             complement(655..990)
                     /locus_tag="VWX69_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191959.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(1078..2388)
                     /gene="der"
                     /locus_tag="VWX69_000568"
     CDS             complement(1078..2388)
                     /gene="der"
                     /locus_tag="VWX69_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU9191960.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(2402..3115)
                     /locus_tag="VWX69_000569"
     CDS             complement(2402..3115)
                     /locus_tag="VWX69_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU9191961.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(3112..4008)
                     /gene="dnaI"
                     /locus_tag="VWX69_000570"
     CDS             complement(3112..4008)
                     /gene="dnaI"
                     /locus_tag="VWX69_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU9191962.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(4009..5178)
                     /locus_tag="VWX69_000571"
     CDS             complement(4009..5178)
                     /locus_tag="VWX69_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU9191963.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(5179..5652)
                     /gene="nrdR"
                     /locus_tag="VWX69_000572"
     CDS             complement(5179..5652)
                     /gene="nrdR"
                     /locus_tag="VWX69_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU9191964.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            5792..6157
                     /locus_tag="VWX69_000573"
     CDS             5792..6157
                     /locus_tag="VWX69_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9191965.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            6162..6857
                     /locus_tag="VWX69_000574"
     CDS             6162..6857
                     /locus_tag="VWX69_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191966.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            6874..7641
                     /locus_tag="VWX69_000575"
     CDS             6874..7641
                     /locus_tag="VWX69_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191967.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(7994..9193)
                     /locus_tag="VWX69_000576"
     CDS             complement(7994..9193)
                     /locus_tag="VWX69_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9191968.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(9190..10083)
                     /locus_tag="VWX69_000577"
     CDS             complement(9190..10083)
                     /locus_tag="VWX69_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191969.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            10200..10280
                     /locus_tag="VWX69_000578"
                     /pseudo
     CDS             10200..10280
                     /locus_tag="VWX69_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10790..10978
                     /locus_tag="VWX69_000579"
                     /pseudo
     CDS             10790..10978
                     /locus_tag="VWX69_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11393..12010
                     /locus_tag="VWX69_000580"
     CDS             11393..12010
                     /locus_tag="VWX69_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU9191970.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(12330..13217)
                     /locus_tag="VWX69_000581"
     CDS             complement(12330..13217)
                     /locus_tag="VWX69_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9191971.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(13366..15249)
                     /locus_tag="VWX69_000582"
     CDS             complement(13366..15249)
                     /locus_tag="VWX69_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9191972.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            15626..17080
                     /locus_tag="VWX69_000583"
     CDS             15626..17080
                     /locus_tag="VWX69_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9191973.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRTSEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            17061..18026
                     /locus_tag="VWX69_000584"
     CDS             17061..18026
                     /locus_tag="VWX69_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9191974.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKPAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(18061..19335)
                     /locus_tag="VWX69_000585"
     CDS             complement(18061..19335)
                     /locus_tag="VWX69_000585"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU9191975.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(19335..20507)
                     /locus_tag="VWX69_000586"
     CDS             complement(19335..20507)
                     /locus_tag="VWX69_000586"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU9191976.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(20638..20886)
                     /locus_tag="VWX69_000587"
     CDS             complement(20638..20886)
                     /locus_tag="VWX69_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191977.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPISQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(20954..21579)
                     /locus_tag="VWX69_000588"
                     /pseudo
     CDS             complement(20954..21579)
                     /locus_tag="VWX69_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(21641..22090)
                     /locus_tag="VWX69_000589"
     CDS             complement(21641..22090)
                     /locus_tag="VWX69_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9191978.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(22092..22850)
                     /locus_tag="VWX69_000590"
     CDS             complement(22092..22850)
                     /locus_tag="VWX69_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9191979.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(22965..24944)
                     /gene="pknB"
                     /locus_tag="VWX69_000591"
     CDS             complement(22965..24944)
                     /gene="pknB"
                     /locus_tag="VWX69_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU9191980.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(24941..25681)
                     /locus_tag="VWX69_000592"
     CDS             complement(24941..25681)
                     /locus_tag="VWX69_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU9191981.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(25696..27009)
                     /gene="rsmB"
                     /locus_tag="VWX69_000593"
     CDS             complement(25696..27009)
                     /gene="rsmB"
                     /locus_tag="VWX69_000593"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU9191982.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(27002..27937)
                     /locus_tag="VWX69_000594"
     CDS             complement(27002..27937)
                     /locus_tag="VWX69_000594"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU9191983.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHAFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(27950..30346)
                     /locus_tag="VWX69_000595"
     CDS             complement(27950..30346)
                     /locus_tag="VWX69_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU9191984.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHARDVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(30412..30726)
                     /locus_tag="VWX69_000596"
     CDS             complement(30412..30726)
                     /locus_tag="VWX69_000596"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU9191985.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(30751..31377)
                     /gene="gmk"
                     /locus_tag="VWX69_000597"
     CDS             complement(30751..31377)
                     /gene="gmk"
                     /locus_tag="VWX69_000597"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU9191986.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(31507..33120)
                     /locus_tag="VWX69_000598"
     CDS             complement(31507..33120)
                     /locus_tag="VWX69_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU9191987.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(33190..33480)
                     /locus_tag="VWX69_000599"
     CDS             complement(33190..33480)
                     /locus_tag="VWX69_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9191988.1"
                     /translation="MEVEEKSIELSYEYVDDGYSGSNFERPNFKNMIDDLNKGKFSII
                     MVKDLSRFGRDYIESGKYLQKIFPEKGIRFISVNDNYDSDNADVSDIHLRFV"
     gene            complement(33603..34361)
                     /locus_tag="VWX69_000600"
     CDS             complement(33603..34361)
                     /locus_tag="VWX69_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191989.1"
                     /translation="MKFKNYLFDLYPYFPKGFSLDNREDPDVCSKALYDDLCKMFFDD
                     DSKEKLKITSVCNKCQNYGNRDYYTLFIDKDKYLLSSDYIGASIYWAQEAGLNDRIIL
                     DHLSISRTIGGHILFPRGGKLETVNQARGGEKGYYDRFDLTLYAIKEWFVENKNTKIG
                     YAIENYHEWFELFSGDDNCKNGFENFVEFFKLEGFIYEQNKIIDLIKSDLENNQVVFL
                     DKEDILIASTEEEYIRYMKNLNIIILERTKKILL"
     gene            complement(34377..34517)
                     /locus_tag="VWX69_000601"
     CDS             complement(34377..34517)
                     /locus_tag="VWX69_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191990.1"
                     /translation="MLFYLTKELNSGVKKIGTISTTLVVVAGVSAGVLGGKFDFKFPK
                     KI"
     gene            complement(34471..34974)
                     /locus_tag="VWX69_000602"
                     /pseudo
     CDS             complement(34471..34974)
                     /locus_tag="VWX69_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370715.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
     gene            complement(35191..36080)
                     /locus_tag="VWX69_000603"
                     /pseudo
     CDS             complement(35191..36080)
                     /locus_tag="VWX69_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(36210..37307)
                     /locus_tag="VWX69_000604"
     CDS             complement(36210..37307)
                     /locus_tag="VWX69_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU9191991.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLSYILAQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNLSIAQQNFGRVPIRIETN"
     gene            complement(37317..38057)
                     /locus_tag="VWX69_000605"
     CDS             complement(37317..38057)
                     /locus_tag="VWX69_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9191992.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(38377..38730)
                     /gene="rsfS"
                     /locus_tag="VWX69_000606"
     CDS             complement(38377..38730)
                     /gene="rsfS"
                     /locus_tag="VWX69_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU9191993.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(38743..39243)
                     /locus_tag="VWX69_000607"
     CDS             complement(38743..39243)
                     /locus_tag="VWX69_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9191994.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(39244..39837)
                     /gene="yqeK"
                     /locus_tag="VWX69_000608"
     CDS             complement(39244..39837)
                     /gene="yqeK"
                     /locus_tag="VWX69_000608"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU9191995.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(39837..40466)
                     /locus_tag="VWX69_000609"
     CDS             complement(39837..40466)
                     /locus_tag="VWX69_000609"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU9191996.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(40518..40829)
                     /gene="yhbY"
                     /locus_tag="VWX69_000610"
     CDS             complement(40518..40829)
                     /gene="yhbY"
                     /locus_tag="VWX69_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU9191997.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(41043..42149)
                     /gene="yqeH"
                     /locus_tag="VWX69_000611"
     CDS             complement(41043..42149)
                     /gene="yqeH"
                     /locus_tag="VWX69_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU9191998.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFITGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(42152..42742)
                     /locus_tag="VWX69_000612"
     CDS             complement(42152..42742)
                     /locus_tag="VWX69_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU9191999.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(42694..43602)
                     /locus_tag="VWX69_000613"
     CDS             complement(42694..43602)
                     /locus_tag="VWX69_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9192000.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDKPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(43659..44219)
                     /locus_tag="VWX69_000614"
     CDS             complement(43659..44219)
                     /locus_tag="VWX69_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU9192001.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            44358..45567
                     /gene="sstT"
                     /locus_tag="VWX69_000615"
                     /pseudo
     CDS             44358..45567
                     /gene="sstT"
                     /locus_tag="VWX69_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            45635..46588
                     /locus_tag="VWX69_000616"
     CDS             45635..46588
                     /locus_tag="VWX69_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9192002.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            46731..47111
                     /locus_tag="VWX69_000617"
     CDS             46731..47111
                     /locus_tag="VWX69_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9192003.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETVAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKILASLQKTVEESLEAGLDFLI"
     gene            47210..47431
                     /locus_tag="VWX69_000618"
     CDS             47210..47431
                     /locus_tag="VWX69_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9192004.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            47448..47762
                     /gene="trxA"
                     /locus_tag="VWX69_000619"
     CDS             47448..47762
                     /gene="trxA"
                     /locus_tag="VWX69_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9192005.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            48067..48600
                     /gene="queF"
                     /locus_tag="VWX69_000620"
     CDS             48067..48600
                     /gene="queF"
                     /locus_tag="VWX69_000620"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU9192006.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
     gene            48650..>48828
                     /locus_tag="VWX69_000621"
     CDS             48650..>48828
                     /locus_tag="VWX69_000621"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192007.1"
                     /translation="MLKAVFEVVDKTDEVSSKHCFEVADRTDKVSLKHCFEVADRTDE
                     VSLKHCFEVADRTDEV"
BASE COUNT        13856 a        10986 c         9331 g        14655 t
ORIGIN      
        1 aattagggga tctaaagcat tttataccaa tgttttataa gttgtattgt attattccat
       61 attcaatcca ctatacaaga tgaatatttc tctcaagttt cataatcaaa ataaaaatga
      121 ctgtatctat agctccataa acaaatcata gatacagtca ttttttagtt cctacacctt
      181 cctttatgca cacctttaga tttccctagt tcccgcctca agcgaatcat ttttttgaaa
      241 aagacatagg ctaaccaatc actagcaaaa gcgataagta gtaataatag ccaaataccc
      301 cataacttga tatctgtcaa atttctcaag acgatattga aaaacagaac tgaaaaaact
      361 gtccaagcaa ggctaaaaag agcatagagg gtgatgtaaa tccagtaaaa atagtaaaaa
      421 attgggaaaa atttactttc tctattatcc ttgtcaatcc agctgaaaaa gtaaaaacag
      481 ggtaataaga ttatcatttt aaacaagtgt tccatcacaa gcctcctttt ttaaattgtt
      541 ttctttagtt tcgttctatt aaatgttatt accaatataa accttggaat agcgtgtaat
      601 aaatgatttt agaggtacca taagccacct cctacaaata gaaaccgata taaatcaatg
      661 ccttccaccc ttagacttcc ctagttcctg tctcaagcga aacatttctt tgaaacagga
      721 ataagttaac caattcatac caatagctag cagaataaaa agaaaccaaa tgccccataa
      781 cttgatatct gtcacatttc tcaagacggt attgaaaaac agaactgaaa caactgtcca
      841 agcaaggcta aaaagagaat agaaggggat gtaaaaccag taaaaataat aaaaaattgg
      901 aaaaaactta ctatttctgt tggccttttc aatccagtta tcaaaataaa agtacggtgc
      961 taaaagtaag aatttaaaca aatgttccat caccgacatc ccccttcttt tgatagcgtt
     1021 ttctattatt ttattatatc aaaaaaatcc ggaactgtca ttccagattc tactttttta
     1081 tttgcgtttt cttgcgatga gatgaatcgg tgttccctca aaaacaaagg ccttgcggat
     1141 ttgattttcc aagaaacgca ggtaagaaaa gtgcatgagt tcttcttcat tgacaaagat
     1201 gacaaaggtt ggtggtttgg ttgccacttg ggtcgcatag aaaatcttga gacgttttcc
     1261 tttgtctgtc ggtgttgggt tgatggcaat ggcatccatg atgacatcgt tcaagacagc
     1321 tgatggaata cgtgtatttt gactttcgct gatttgctta atcatctcag gaagtttgtg
     1381 gagacgttgc ttggttaaag ctgatacaaa gataatcggt gcgtaaggca ggtattggaa
     1441 ctgctcacgg atatcttctt cccagttttt catagtgtgg ttatcttttt caagcgtatc
     1501 ccacttgttg accacgataa tcatcccttt accagcttca tgagcaaatc cagcgatacg
     1561 cttgtcgtat tcacgaatcc cctcttccgc attgatgacc attaagacca catctgaacg
     1621 gtcaatagca cgcatggcac gcatgacaga gtacttctca gtattttcat aaaccttacc
     1681 agacttacgc ataccagccg tatcaatcat ggtaaactct tgaccatctg tatctgtaaa
     1741 gtgggtatca atagcgtcac gagttgttcc agcaacagga ctggcaatga cacggtcttc
     1801 tcccaagata gcattaatca agcttgattt tccaacgtta ggacgaccaa tcaagctaaa
     1861 cttaatgaca tctggatttt cttcttcata ttcatttgga aggttttcca caatcgcatc
     1921 tagtacatcc cctgtaccga taccatggac agatgagata ggcagtggtt cacccaaacc
     1981 gagagcatag aaatcataga tatcatttct catctcaggg ttgtccacct tgttgactgc
     2041 gaggataact ggtttgtggg tcttataaag cttacgagct acgtattcgt ctgcatcagt
     2101 aattccttcc ttaccagaca cgacaaaaac gataacatct gcttcttcca tggcaatttc
     2161 tgcctggtgc ttgatttgtt ccatgaaagg agcatcgaca tcatcaattc ctcctgtatc
     2221 aatcatgcta aaagaacgat tgagccactc acccgttgca taaatacggt cacgtgtcac
     2281 tccttcgaca tcttctacaa tggagattcg ctcaccagcg atccgattaa atagggttga
     2341 tttcccaaca ttgggacgtc ctacaatggc aatagttggt agggccataa tttctcactt
     2401 tctacaataa tttcttctgt tcaagatttt ttctagttga gcttggttca gcttgaccaa
     2461 actgttctgc taggcgctga ctccagcttg tggtcgcacg cgccccagca tagtcagcct
     2521 gaacacggtc ataagcttgg attgcctcag ttgactgttc ttggtattct tcctcaaaga
     2581 caacattctc tagtggcagt ctcggtttca tatcatgatg ttgatttggc acacccagtg
     2641 ccatcccaaa gacagaatag gtgtagtcag gtaggttaaa gagctctgcc acttcttcag
     2701 acttgtatcg aaccaaaccg ataatcacac caccatagcc caagctttca gctgccaaca
     2761 aggcgttttg tccagcaaga gctgcatcga ccgaactaat caagagacct tccacacctt
     2821 ggggttggaa ggtgtcggta tgaagtctgg ctcccttttc tgctcggttc aaatctccga
     2881 caaagagaag gaaaacagca gactggcgaa tggcttcttg aggtaccaat tcatacaagg
     2941 catctttctt ctcttgactt cgtaccacaa tcacagagta ggattggaaa ttcttccaag
     3001 atgatgccat ctgggctgct gtcaaaatct catttaagtc tacttgggga atttcttgct
     3061 ctttaaacct gcgcactgaa gtatgagcct tcatcaattt aatggtttct gtcatcgacg
     3121 gtttactcct tctaaacgag tctcctcagc caaataacgg atgcgttcca tgacccgtct
     3181 ggcttcccag gtttcgtcat ttccatgttt cactttcgca aaatgcttct ccaaatcttc
     3241 aaagttgaag ttggatgtga aaaaggtcgg taaattttcc tgcatccgat attggagaat
     3301 gacctgcagg atttcatcac gcacccaagc ggtggattgc tcggcgccaa tatcatctaa
     3361 aatcaggacc tcagacagct taatctcatc caccaaggtc ttaacattgc catcactgat
     3421 agcatttttg acatcaatga caaagctagg atagtggagg agagttgatg aaacaccacg
     3481 tttttctgat aaatcatgag ctaaggccgc caccatgaaa cttttaccca caccaaagtc
     3541 tccatataag taaagacctt ttcgaatagc tggatattgc tccacgaagg ctagtagctt
     3601 ttcaaaaact ggtaagcgcc ccaaatcatc caagtcaact tgagccaaac tagctttctt
     3661 gagactggct ggtagattga ttaacttgag acggttctta atagccgctt ctttttcagc
     3721 cgcgattagc tcaggagttt cttcatatga aacatctgca tagccatgat tcttaaccaa
     3781 aatcggcttg tagcctttgg caatataatc cgtatcccca cggagaaact tgtcacgctc
     3841 ggtgatgtac tgattaaact tggagatact gcgatttaat tcctctggag tcaaggattc
     3901 ttgctggata aaagccgcaa catcagggtc cttcatgatt ttctggacca aatcttgata
     3961 ataaaaacgg ctgggttgac gtttgagtac gtctccgaca ctttccatct aatctcctcc
     4021 tttttctaat cgagctaata gttcttgctt cttacgttct agttccagac gagtttcctc
     4081 gctggtttca ttcttatatt caggattact ccatttagga acattggttt ttactggggc
     4141 agtctgattc tgtttttgtg tttttgcttt ctgtcctcgc tcacggatgc gcaagactgc
     4201 cttttctgcc gaatgaatct tttgataggc atagtcattg gctaccttca tggcatattt
     4261 ctcattgata tttgccgaat cgaccttatt aaaggtcaat aaaagaatga tattgatgac
     4321 ttcgtccagc aagcccaagc cagccatctg ttgcaagagt tctctttctg tttgggtaat
     4381 ggttcccttg cgtgtttgct tgatttctgc caagaactgc agggcagttt tacttttggc
     4441 ttctttgata atggttgttt ccttaagact aaagtcagag gaaactggtt tttgagcaat
     4501 tttttcacgc atgcgtttgg ttgaaataac ctgagaaaca gctgttgact tggccaattg
     4561 ataggtttca aaccaagtcc atttcttctc ctcggcaata gcaaagaggt ttaagacatc
     4621 ggactgctca tccgcaaaac gaagtccatc tcgagccatc agctggcgaa aatgttccaa
     4681 gtcaaaatca ttggccactt tcttcttgag accaaggtct tcttgactgc ctagttctgc
     4741 caattctgga aagacttgat tgagtgagac aggtatttct tcaccatcag cactttcaac
     4801 tttcaaatcc tccacagcag agtcgccaat ctttttctct aagagtctgc gataaacagg
     4861 atgctccaag aagtcttgac tagatagagg agcatggagg gctagctgat aaacatcccc
     4921 cttttgatag agggtcaaga gattaaaagc agataagatt ttcaatgatt ttatcagtct
     4981 atccatccca aagttgagat gattgaggat acttgaaaaa agatattcct ttctaccatt
     5041 atcccaaaaa ctgattgtat aaagataaag gctcagtgcc tcctgaccga taatcgggag
     5101 gtagcactgt accagagatg aggtatcttg cgacacccga ttattcttta gataagaaaa
     5161 acggtcaatt ggcttcattt atctttcctt tttcttttta gaggactggg tgatttgttg
     5221 gagcaagctc tctaactcac tgacatcctt aaaactacga tagacactag caaaacgtac
     5281 ataggtaatc tcgtccaatt cagccaactc ctccatgacg agtgaaccaa tgtcctcact
     5341 ttgaatttca ttttcatttc gaccacggag tttctgttcg atacgattga ctaccatgtt
     5401 gatttcatca cttgacacag gacgtttctg ggctgagcgg ataatcccat taaagatttt
     5461 atctctggag aattgttccc gtgtgccatc ttttttaaca accactaagg ttctttcttc
     5521 tactcgttcg taggttgtaa aacggtgttg gcactcgtcg cactctcgtc ttctacgaat
     5581 ggtgttccct tcttctgctt ggcgactatc gataacactt gacttggtag ccccacattt
     5641 tggacaacgc atcctttccc tccttatcgt tttcttttca ttataccatt ttttaagcga
     5701 ttcccaaaac aattcttctt tttgcttgac aagttttttg ttttgttgta ttatttaatt
     5761 aagacaaaag gataagagaa aggagactaa gatgtcctgg acatttgaca acaaaaaacc
     5821 catctattta cagattatgg agaaaatcaa gcttcagatt gtttcccata cactggaacc
     5881 caatcaacaa cttccaaccg tgagggagct agctagcgag gctggtgtca atcccaatac
     5941 catccaaaga gccttatcag accttgaacg agaaggattt gtctacagca agcgaacaac
     6001 tggacgattt gtgactaagg ataaggagct aatcgcccag tcacgcaaac aattatcaga
     6061 agaagaattg gaacacttcg tttcctccat gacccatttt ggctatgaaa aagaagaact
     6121 accaggcgta gtcagtgatt atattaaagg agtttaagcc tatgtcatta ctagtatttg
     6181 aaaatgtatc caaatcatat ggagcaacac cagcccttga aaatgtttct cttgacattc
     6241 cagctggaaa aattgtcggc cttcttgggc caaacggctc aggaaaaaca accctgatta
     6301 aactaattaa tggcctctta caaccagatc aaggacgtgt cctcatcaac gacatggacc
     6361 caagcccagc aaccaaggcc gttgtagctt atttgcctga tacgacctat ctcaatgagc
     6421 aaatgaaggt caaagaagcc ctaacctact tcaagacctt ctataaagat ttcaatcttg
     6481 aacgcgccca tcatctactt gcagacctgg gcattgatga aaatagtcgt ctcaagaaac
     6541 tatcaaaagg aaacaaagaa aaggttcaac tgattttggt tatgagccgt gatgctcgtc
     6601 tctatgtttt ggacgaaccc attggtgggg tggatccagc agcccgtgct tatatcctca
     6661 ataccattat caacaactac tcaccaactt ctaccgtttt gatttctacc cacttgattt
     6721 ctgatatcga gccaatcttg gatgaaattg tcttcctaaa agacggaaaa gtcgtccgtc
     6781 aaggaaatgt agatgatatt cgctacgagt caggtgaatc cattgaccaa ctcttccgtc
     6841 aggaatttaa ggcctaagca aaggagatta tttatgtttt ggaatttagt tcgctacgaa
     6901 tttaaaaatg ttaacaagtg gtatttagcc ctctacgcag ccgtgctagt cctttctgcc
     6961 ctcatcggaa tacagacaca aggctttaaa aatctacctt accaagaaag tcaggctact
     7021 atgctacttt ttctagctac agtctttggt ggcttgatgc ttacacttgg gatttcaacc
     7081 attttcttga ttattaaacg cttcaaaggt agtgtctacg accgacaagg ctatctgact
     7141 ttgaccttgc cagtttctga acaccatatc atcacagcca aactaatcgg tgcctttatc
     7201 tggtcattga ttagcaccgc tgtattggct ctaagtgctg ttattattct ggctttaaca
     7261 gctccagaat ggattcctct ttcttatgtg attacatttg tagaaacaca tctccctcag
     7321 atctttctta caggtatatc cttcctacta aatactattt caggaatcct ctgcatctac
     7381 ctggctattt ccattggaca gcttttcaat gaataccgta cagcactcgc tgttgcagtc
     7441 tacattggta tccaaatcgt cattggattt attgaacttt tcttcaatct tagttctaat
     7501 ttctatgtca attcactggt aggactcaat gaccatttct atatgggagc aggtatagcc
     7561 attgttgaag aactcatatt catagctatc ttttatctcg gaacctacta catcttgaga
     7621 aataaggtta atttgcttta aataattttt acctagatat gtaacatact catagaacaa
     7681 aagagaccag gcaaaaagtc tttacaatta gaaaacgcat agtatcaagt gttaaaaatc
     7741 cttgatatta tgcgtttttt gtgagctgac ttatttcctt tcactatatc gcaaaatgaa
     7801 ataagaacgg aacgatggga ttttggaatt caaatcaatt tataagaatg ttttagaagt
     7861 aatattatcc tattccagat tcagttcact atacaattga gttttcaagc aacctgttta
     7921 cataatgtgt acataattag gttcgtgatt ccaccctttt cacctttaaa aacctcgctt
     7981 tcgcaaggct cttctattta taagataagg cacgtttaaa ggttttccaa atccctaaat
     8041 catccgtttg aagaacgaga ctagcataca tgcgtccgat aaatcctgtt gctaccaccg
     8101 caaaaatcac tgtaatagca agtgaaatcc atgcttccgc tccctccgca tagccattaa
     8161 tcgttcgaaa cggcataaag aaggtcgaaa taaagggaat ataagaacca atcttcaaga
     8221 ggagattgtc accagctgca cctagagctg tcactccaaa aaaaccaccc ataatcaaaa
     8281 tcatcaaagg cgacaaggct ttccctgagt cttcaggacg agaaaccata gatcctagga
     8341 aggctgccaa gactacgtac atgaaaagac tgatcaaaat aaagagcaag gtattcagtg
     8401 agatagcatc tcccaagtga tccaaaatac cagactgagc caagaatggc aaatctttaa
     8461 agagcaaaac ggcagccaga ccacctacaa catagatccc aatatgcgtt aaaatcacta
     8521 gaaacagagc catcatccgc gcatagaaat agtgacttgc ccttatgcta gaaaagacga
     8581 cttccataat tttggtgcct ttttcactgg caacttcctg agctgttaca cccgcatagg
     8641 taatcagaat catataaaga aagaatccta aggcacctgc tgcaattgtt tgaataaact
     8701 ttttattttc cttggcttca tcaatctttt ctgtgaattg aattgtctgc gctaagcgtt
     8761 tttcctgctc ttgagacaag gaagcagttg aacgattaag ctgattttgc agttcattga
     8821 gtgtacctgt aacctcaaat ttaattccat tttcaagcga tgtttcgcca tgataaactg
     8881 cctttagaac actatcttct tgatcaatgg tcaaataacc ttttaatttt tcttctttaa
     8941 ttgcttcttt ggcacttgct tcgtctttat agtcgaagtt aacaccattt acattcttca
     9001 gtccttctgc tacagatggc actgttgtca ctactgccac tttattattt ttagccatag
     9061 aagaaccttg gagatgccca attcctacag agattcctaa aaagaggaac ggcgaaatca
     9121 ccataaagaa gaaactccat gactcgacat gtcgaagata ggtttccttg attacaaccc
     9181 acatatttct catacttcca ctcctgattc tagtttaaag atttcatcga tagttggcgc
     9241 ttgttggtca aatgttgcga tatattgacc ttgagtcaag attgggaaga gttcccttcc
     9301 agcgctctca tcctccaaaa tcaatttcca actgccttgt ttggtcaagc tcacctgttt
     9361 gacatgagga agattttcca attcttcctt gcttcgttca cttgaaacaa agagacgcgt
     9421 tttcccgtat tgattgcgga catcctgaac tggtccgtgc aagaccacac ggccatctcg
     9481 aatcatcaga atatcgtcac aaagttcctc aacattggtc atgacatggt cagaaaagat
     9541 aatggttgct ccgcgctctt tttcctgaaa aatgacttgt ttgagcaatt ctgtattaac
     9601 tgggtccaat ccactaaaag gctcatccaa gataatcagg tctggttcat gaatcagagt
     9661 aataatgagc tgaatcttct gctgatttcc ttttgacaga ctcttgattt tatctgtcag
     9721 ctttcctttt acttccaacc tcttcatcca ttgagggagt ttttctttga cttctttggc
     9781 atccatgcct tttagagtcg ccaagtagcg aacttgttca agaactgtca atttaggcat
     9841 gagactgcgt tcttcaggca gataaccaat ccgagcatag atctcctgac gaatatcctg
     9901 accatccaga ccgatttctc cctgatattc taggaatttt aaaatactat ggaaaatcgt
     9961 tgtttttcca gcaccatttt ttccgactag tcccaaaata cgacctggtc gcgcttgaaa
    10021 gtcaatacca aacaaaactt gcttggatcc aaaacttttc tctagacttc ttacttctag
    10081 catctttcac ctccgaaatt tcttgcactc attatactcc tttttgatag cctttacaat
    10141 gttttttgtc catttttaga agactattgc tgtgtaaaat atggcctgga gcacttttat
    10201 actcaatgaa aatcaaagag caaactagga agctagccgt agactgctca aagtacagct
    10261 ttgaggttgc agataaaact gacgaagtca gctcaaaaca ctgttttgag gttgtggata
    10321 gaactgacga agtcagtaac tatacgtacg gcaaggcgaa gctgacgtgg tttgaagaga
    10381 ttttcgaaga gtattagtga taaatccatt atacagcagc aaacttaatt tataccttcc
    10441 gctcctcaac tgtctatttt taatcctgaa ttgttatttg agtaactcct ttttcctcgt
    10501 aaagttttct tcctctaaaa cttctggaaa aaggctaata gtttcagaca acatttttat
    10561 aagaaacaag ttcatctgtc atttcaagaa ggagtaatcc tttatctact aatggacgga
    10621 acagaattca accgcttgtc cgatatgttt tctaaggatt atatagtaaa atgaaataag
    10681 aacaggacaa attgatcagg acagtcaaat tgatttctaa caatgtttta gaagtagatg
    10741 tatactattc tagtttcaat ctgctatatc tattatgcac acccctatag gatctaatga
    10801 aaatcacaac aggctcattc atagatagtt acctcaggaa actaagaaaa cgactacaaa
    10861 ggaagtcgca ttcatcgaaa agtggattaa caactatcct aaaaaatgct tgaactacaa
    10921 gtcccccaga gaagacttct ggatgactaa cttgaacttg aaatttagca ataattaatt
    10981 caccatctaa ctatatttag taattatttc agaactgatt aatattaaaa ttaactaaca
    11041 attcaaagga ttcatactag ccataaatta cgtccatcag agagagactc ttactacttt
    11101 tagattttag tctttctagc ttcagaatac atctaaactt tagggaaaat gactattcga
    11161 aagcgcgaat gcctcaaaat tatctcagat aagctattcg aaacttagaa tgcttttaaa
    11221 tttatggaat tgcgattatt cgaaacctag aatgcatata acctttagtt gacagaccta
    11281 ttctaagtct cgaagggcta tttactttct attccttatc aaaaaagact cattccccct
    11341 ttctcctcca aaatatggta tagtagaaat atactatcta tgaggagttt acatgtcaca
    11401 ggataaacaa atgaaagctg tttctcccct tttgcagcga gttatcaata tctcatcgat
    11461 tgtcggtggg gttgggagtt tgattttctg tatttgggct tatcaggctg ggattttaca
    11521 atccaaggaa accctctctg cctttatcca gcaggcaggc atctggggtc cacctctctt
    11581 tatcttttta cagattttac agactgtcgt ccctatcatt ccaggggcct tgacctcggt
    11641 ggctggggtc tttatctacg ggcacatcat cgggactatc tacaactata tcggcatcgt
    11701 gattggctgt gccattatct tttatctagt gcgcctatac ggagctgcct ttgtccagtc
    11761 tgtcgtcagc aagcgcacct acgacaagta catcggctgg ctagataagg gcaatcgttt
    11821 tgaccgcttc tttattttta tgatgatttg gcccattagc ccagctgact ttctctgtat
    11881 gctggctgcc ctgaccaaga tgagtttcaa gcgctacatg accatcatca ttctgaccaa
    11941 accctttacc ctcgtggttt atacctacgg tctgacctat attattgact ttttctggca
    12001 aatgctttga cacgtaaaaa atccgtttgg tttcccaagt ggatttttaa agcgtagatt
    12061 aactatagct tgatactaaa tatactttgg tatggaaatc atgcatattt ttcgatagtg
    12121 aagcgaggac ttacctagcc tttccaccgt gatagaaaca cctgaaatct aatggtttca
    12181 ggtgttcgga aactttgagc ctagtgtctc aaagtttagg tatggaattt cgaagaaagt
    12241 cgctaccgtc cgtaatcact taaggaaagg ctcaaaaata ttgttttcaa ccacaaaatc
    12301 cgtttggttt cccaagcgga ttttgtgctt tattttgaaa cttcttttgc aagaacaaag
    12361 ttcccaagtg tggcagaacc atttcctgcg actgctggcg tcacgatata gtcacgcaca
    12421 tctggtactg gtaggtaacc attaagaaga gatgtaaatt tctcacggac acggtccagc
    12481 atatgttgtt gagccatgac ccctccacca aagacaatca cgtctgggcg gaaagtcact
    12541 gtcgcattaa ccgcagcttg agcgatatag taggcttgaa catcccaaac agggttgttg
    12601 agttcaatag tttccccacg tacacctgta cgagcttcca aacttggacc agctgcatag
    12661 ccttccagac atcccttatg gaaaggacaa acacccttaa actctttttc aatatccatt
    12721 gggtgtctag caacataata atgacccatt tcagggtgac ccacaccacc gataaactca
    12781 ccacgttgga tgacgcctgc accgatacct gtaccgattg tgtagtaaac caagttttcg
    12841 atacgaccac cagcattgtt acgggcaacc acttcaccgt aagcagagct gtttacgtct
    12901 gttgtgaagt acattggcac gtttagggcg cgacgaaggg caccaagcaa gtccacattt
    12961 gcccagtttg gttttggagt cgtcgtgata aagccataag tttttgagtt tttgtcaata
    13021 tcaatcggcc caaatgaacc aactgcaaga ccagcaaggt tatcgaattt tgagaagaac
    13081 tcaatggttt tatcgattgt ttcgattgga gttgttgttg gaaattgtgt tttttctaca
    13141 acgttaaagt tttcatcacc gacagcacag acaaactttg taccgccagc ttccaagctt
    13201 ccatataatt ttgtcatgat aaacctcttg tttttatttt ctttattata gcatacttcg
    13261 aaagtctaaa tgtctctatt ttttagattt tcctctgtaa atcttactat ctaataaaaa
    13321 cgaacaaaca tgtcatttgt tcgttttcac attagagagg attgattaga ttttcacttc
    13381 gatcacagca tcccccttcg caactgaacc tgttgcgact ggagctactg aagcgtagtc
    13441 agctgtattt gtaacgataa ccattgttgt atcatcaagt ccagctgtag cgattttatt
    13501 tgagtcaaat gttccaagaa catcgccaac tttcacctta tcaccttgag caacttttgc
    13561 ttcaaaaccg tcaccgttca tagatacagt gtcaatacca acatgaatca aaacttcagc
    13621 accatttctt gttttcaaac caaaagcgtg ccctgttgga aaggcaattg aaacttcagc
    13681 atcagctggt gcatagacca cgccttggct tggtttcaca gcgatacctt gtcccatagc
    13741 tccacttgag aagactgggt cattgacatc agcaagagcg acaacatcac cgacgatagg
    13801 agttacaagt gtttcatttt gaagagctgc tggcgcaact tcttcttttt cttcagccac
    13861 ttcagcttgt tttgcagctg cagttgcgtc tacttcatct tcgtaaccaa acatgtaagt
    13921 aagagcaaaa ccaagggcaa atgatacagc taccataaga aggtattgtg gaagttgtcc
    13981 gttaccaaca taaagcattg taccagggat gatggtgata ccattaccag taccagcaag
    14041 tccaaggata gaagccaatc caccaccgat tgcaccagca atcaatgaaa ggaagaatgg
    14101 tttacggaag cgcaagttca ccccgaagat agcaggctct gtaataccta ggaaggcaga
    14161 aagagcagcc gggaaagcaa gtgttttcag ttttggattt tttgttttaa caccaaccgc
    14221 aacagtagca gcaccttgag ctgtcatagc agctgtgatg atagcgttga atgggttagc
    14281 atggtcagca gcaagtaatt gcacttcaag caagttgaag atgtggtgca cacctgacac
    14341 gacgatcaat tggtgaaccc caccaatcaa gaaaccacca agaccaaatg gcatgctaag
    14401 aatcgctttt gtagcaataa ggatgtagtt ttcaacaacg tggaaaactg gtccaatgac
    14461 aaagagtcca aggatagaca tgaccaaaag tgtcacgaat ggtgttacca agaggtcaat
    14521 gacatctgga acaaccttgc ggacagcttt ttcaaattta gctccgacaa ccccgatgat
    14581 gaaggctgga agaacggaac cttgcaaacc aacaacaggg atgaaaccaa agaagttcat
    14641 cgctgttact tcaccacctt gagcaactgc ccaagcgttt ggaagtgagc cagagacaag
    14701 catcatacca agaacgatac caacggcagg atttccacca aatacacgga aggttgacca
    14761 cacaaccaaa cctggcaaga tgatgaaggc tgtatctgtc aagatttgtg tgtaagttgc
    14821 aaagtcacct ggaagtggca tttcaagagc gttgaaaaga ccacgcacac ccatgaagag
    14881 acctgtcgct acgataactg ggatgattgg aacgaaaaca tcaccaaaag tacggatagc
    14941 acgttggaac cagttccctt gtttagcaac ttctgctttc atgtcatcct tagatgatgt
    15001 tggtaatcca agtacaacaa cttcatcgta cattttgtta actgtacctg taccaaagat
    15061 aatttggtat tgccctgagt taaagaaagc accttgaact ttttccaagt tctcaatcac
    15121 ttctttattg attttctctt catctttgac catgacacgt agacgtgtcg cacagtgggc
    15181 aacactattg acattttcac gtccgcccaa ggcatcgatg actttttttg caatttcctg
    15241 attgttcatt tgcaaaaatc tccttatata acattttgtt cttgtttgaa agcgatttta
    15301 ttcgccctta cgactattat tttatcatgt tttaaaaata tgtcaagcgt tttgcagaaa
    15361 aaatattcta tctacttagt gggcaagctt tagattgatt gtttttgact gtttcatcag
    15421 gaatttcttg aaaaataagt ttgaaacctt ggttaaaaag tcttttattt cattatcttt
    15481 cacattttcg taaaaatttg attgatttcc tgtatttatt ttatgataat cgtttgacag
    15541 ttttttctct tttttaacat aaagggcttg cattttttat cgaaaacagt tactattaaa
    15601 agtgataaga tttttggagg aatgaatgga atggacaact gagcgtcgtt acagacttta
    15661 tcaagattgg acgcaagaag aaattcaaca tataaaggaa aatatggcac aatctccatg
    15721 gcatactcat taccatgttg agccaaaaac aggacttctc aacgacccaa atggcttttc
    15781 ttactttgat ggcaagtgga tcctctttta ccagaatttt ccttttggtg cagcccacgg
    15841 tttaaaatct tgggcacagc tagaaagtga tgatttggtt cactttagag aaactggagt
    15901 caaagttttg ccagatactc cattagatag tcacggtgcc tactctggtt ctgccatgca
    15961 atttggcgat aacttattcc tattttatac aggaaatgtt cgcgatgaaa actggatccg
    16021 tcacccatac cagatcggtg ctttgatgga caaggagggt aagattacaa agattgacaa
    16081 gatcttgatt gaccagccag cagactctac tgaccacttc cgcgatccac aaatttttaa
    16141 ctttaaaggt caatactatg ctgtcgtcgg tggacaggac ttggagaaaa aaggcttcgt
    16201 ccgtctctac aaggctgtca ataacgacta cacaaactgg caagcagttg gcgaccttga
    16261 ctttgctaac gaccgtactg cctacatgat ggaatgtcct aatctggtct ttgtagagga
    16321 acagcctgtc cttctctact gtccacaagg attggataag aaagttctag actacgataa
    16381 tatctttcca aatatgtata agattggggc ttcctttgac cctaaaaatg ccaaaatggt
    16441 agatgtgtct caacttcaaa acatggatta cggtttcgaa gcctatgcaa ctcaagcctt
    16501 caacgctcct gatgggcgtg ctctagcagt tagctggctt ggtttgccag atgtttctta
    16561 cccatctgac cgttttgacc accaaggaac cttctctttg gtcaaggaac tcactatcaa
    16621 agacgacaag ctctaccagt atccagtcgc tgctattaag gaccttcgta cttctgaaga
    16681 agccttctca aaccgttccc aaaccaagaa cacttacgaa cttgaactca acttggaagc
    16741 taatagccag agcgagattg tcttacttgc tgataaagaa ggtaagggac tttcaatcaa
    16801 ctttgacctt gtaaacggtc aagtgacagt ggatcgtagc caggctggag agcagtatgc
    16861 ccaagaattt gggataactc gttcttgccc tatcgagaat caggctacta ctgctacaat
    16921 cttcatcgat aactctgtct ttgaaatttt catcaataaa ggagaaaaag tattttctgg
    16981 tcgtgtcttc ccacatgcgg accaaaatgg tatcctgatc aaatctggaa acccaactgg
    17041 aacttactat gaattagatt atggtcgcaa aactaactga tgtcgccaaa cttgcaggcg
    17101 tcagtcctac taccgtttct cgggttatca ataaaaaagg atatctatct gagaaaacca
    17161 tccaaaaagt caatgaagcc atgcgagaat tgggctataa acccaacaac ctggctcgta
    17221 gtctgcaagg aaaaccagct aagttaatcg gcttgatttt ccccaatatt tccaatgttt
    17281 tctatgcaga attgattgat aaattggaac accaactctt caaaaatggt tacaagacca
    17341 tcatctgcaa cagtgaacat gattctgaga aggaacgtga atacatcgaa atgttggaag
    17401 ccaatcaggt ggacggcatc atttctggta gtcacaacct aggaatcgaa gactacaatc
    17461 gtgtgacagc gccgattatt tcctttgacc gaaacctatc gccagacatc cctgtcgtct
    17521 cctctgacaa ctatgctggt ggggttcttg ctgcccaaac cttggtcaag acaggtgccc
    17581 agtctatcat catgattaca gggaatgaca attccaattc gccaaccgga ctgcgccacg
    17641 ctggttttgc atccgtactc ccaaaagctc ctattatcaa tgtttccagt gacttttctc
    17701 ccgtcagaaa agaaatggaa atcaagaata tcttgacccg ggaaaaacca gatgccattt
    17761 ttgcttcgga tgatttgaca gctattctgg tcattaaaat cgctcaagaa ttgggcattt
    17821 ctgtcccaaa agagctcaag gtcatcggct atgatgggac ctactttatc gaaaattact
    17881 accctcaatt ggctactatc aagcaacctt tggaagagat tgcttgtctc actattgatc
    17941 ttctcttgca aaagattgaa ggcaaggaag tcgccacaac tggttacttc ttaccagtta
    18001 cgctattacc aggaaaaagt atttaaacac aagaaaactc agaccgattc gtctgagttt
    18061 ttatgatctt aaattttcga gatagcgctg ggctgtctct aggttaaagg ttttatctga
    18121 gatgaggcgc tctactaggg gagcaacttc agattcacta gccccagcta ggagagctag
    18181 ggatttggcc tgtagtttca tgtggccttg ctggatgccc gtacttacca aggctttgag
    18241 ggctgcaaaa ttttgagcaa gaccgatgga cacgataatc tgggctaatt ctctggcaga
    18301 aggatttcct agtagatcat gactgagagc tacacgtggg ttgaggccga tagagccacc
    18361 cttagtcgct acaggcatgg gcagggtcat ctcaccgacc aattcttctc tttcaaggtc
    18421 cagcgtccag cagctaagac cttgatagcg tccatctcga ctggcaaagg catgggcccc
    18481 agcttcgatg gcacgccagt cattaccagt ggcaatcaaa atcgcatcaa taccattaaa
    18541 aattccttta ttatgagtag cagctcggta aggatcagcc tgcgcaaact gactagccaa
    18601 cgcaattttc tccgcaatct ctcgtccttg atccttttgg cggctcaagt agcgaaaggc
    18661 gatgcgacag cttgcagtca ccagagaatc agtcgcgtag ttggacagga ttcccatgag
    18721 actctgtccc tgactgagtt cttctaagac tggtttcaag gcttccagca tggtgttgag
    18781 catattggca cccatggctt cctgggtatc gacatgaata taaacaacga gaaagtctgg
    18841 ttcgcctttt atctgctcga catgcagatc acgcgcccca cccccacgtt taacgataga
    18901 aggataggct tgattggcaa gctccaagag ctccgctttc ttgctggcaa tcttctcttg
    18961 cgctagttta ggattagcaa cttgataaag ggctacctgc ccaatcatct ggcgctgatg
    19021 gacttgtgca gtaaaaccac ctgcacgctt gatgattttg ctggcatagc tggccgccgc
    19081 aaccacagag ggttcttctg tcacataggg aacggtgtat tcctgaccgt tgacaagtac
    19141 ctccggaacc agcgaataag gcagagaaaa agttcccacc acattctcac tcagctggtc
    19201 tgccacagtc acactcatct gttcatcctt ctccagacta gcttgtctct caggactaag
    19261 gagcgcctga gcttttagca gctcgaggcg ctcttggtat gattttttag aaaatccatt
    19321 ccaacttatc ttcattattt ttcaaccttg ctataacggc gttggtggtc aagaatttca
    19381 accaaggcaa aatcttgatt ttcatagcca gcaaactggg cagagtttgt ttcatccaag
    19441 tttacttcct caaaaaagac cttttcatag tctgcaacgg atagggcagt tcgttggttg
    19501 agcttgttca agcggtcttt atccaaataa gcttcatatc cttcaaccaa ttcaccactg
    19561 aagaactcag ccacagctcc acttccgtaa ctataaaggg cgattttatc cccagctttc
    19621 aagctatctg tattttccaa gagagacaaa agtccaagga aaagtgaacc tgtgtagata
    19681 ttccccacct tttgactgta gagaatagac tggtcaaaat gcttttgtaa gaggtctttt
    19741 ttctcttgag gcaggctctt atccatgatt tttttcaagc cttttagcgc taatttagga
    19801 taaggcaagt ggaaacaaac agccgcaaaa tcatccaaag taagctggta gcgtttttga
    19861 tattcaagcc aagtcgtttt caaactatcc aagtattgtt gggtagaata gacaccattt
    19921 acataaggag ttgtcgagta atttggtcgc cagaaatcca tgatgtcacg ggtctgagct
    19981 acattgtcat tattaaaggc catcatgcgt ggattttgtg taatcaacat agctacactt
    20041 ccagcacctt gagttggttc tcccggagtt tcaataccat atttggcaat atcactggca
    20101 atgaccaaga ccttggactc cggagaattt tccacatgca atttggcata atggagggca
    20161 gctgtcgccc catagcaggc ttctttaatc tcgaaactac gagcaaaggg ctggatgccc
    20221 agcaagccat gcacaaagac ggccgcagcc ttactctggt caattcctga ctcggtagcc
    20281 acaatgacca tgtcaacttc ttgtctttct tgctcagtta aaatagagtc actagcactg
    20341 gccgccaagg tcacgatgtc ctcagttagg ggcgcaatac tcaattcctt gagtaagagt
    20401 cctttactta atttttcagg gtcaattccc ctcgcttctg ctaagtcttg taatttcaag
    20461 acatattgac tggtcgcaaa accaatctta tcaataccga ttgtcatatt tacctctgtt
    20521 ttatcattca tgtaaaaaat cgttctatac tattttatca caaatggcag taaaagagag
    20581 aaaaaagact tgattcacca aatcaagcct cttattggtc atcattttaa agaatgatta
    20641 gttgctagag agttcaccga tataagtagc tttataagct ccattcacag ttatcagctc
    20701 ctggaggatc aaatttcctg agtaaatcct tcccatctca tctacaaatt tttgataaaa
    20761 ctgactgatc ggaatttctc tgacatcctt atcaaatgtc ttatcaagtg ttttactaac
    20821 cttctcagca atcaattgat gctcttgcca tccactttga aactctgagc ccgaactaga
    20881 aaccatgact gggataaaca acaaggtcag tagatttaca gacaataagg aaagtagtag
    20941 acttcctgca aaactagaat cctagttcat gattgataat gccagcaatc aaattcattc
    21001 gtaatccgaa gcgtttacga tgatttcgat aggttgttga aaacatttta aacgttttta
    21061 ctttggcaaa gatgttctca accttgcttc tctccttaga tagcgcatgg ttacaggctt
    21121 tatcttcaac tgttagcggc ttgagtttgc tggatttacg tggagtttgt gcttgaggat
    21181 atatcttcat gagcccttga taaccactgt cagccaagat tttaccagct tatccgatat
    21241 ttctgcgact cattttgaac aacttcatat catgacaata gttcacagtg atatccaaag
    21301 aaacaattct cccttgactt gtgacaatcg cttgagcctt catagcgtga aatttctttt
    21361 taccagaatc attcgctaat tgttttttta ggacaattga tttgtacttc cgtcgcatca
    21421 atcattaccg tgtcttcaga actgagagga gttcttgaaa tcgtaacacc acctttgaac
    21481 aagagttact tcaacccatt ggctccgacg gagtaagttg ctttcgtgga taccaaaatc
    21541 agccgcaatt tcttcataag tgcggtattc tcgcacatat agaaagcgtt gttaatttat
    21601 ttatctcatt tttcagaaaa ttcttttatt tctgtaaagt ctacgatact cgatgtgttt
    21661 ttatataatg atacagtctg agaatcactg ttccgctagc cattccaata gagattacca
    21721 aagccaacat gacaaccaag gtcgcacttg ccagtgcttt attatagtcc cctgtcacaa
    21781 aaaaggcagt tgttcggtag gagagataac ctggaaccag cggtgccaaa atggccaaga
    21841 taaagaccac agcaggtgtc ttataaagaa tacttaaaat ctggctgaca caagaaccaa
    21901 taatggctgc aatgaaggta gctacaatga cattggtcgg ttccttgagc aagagataga
    21961 ttagccagac agtcatgccc aaaatccctc caggtaagag catagaccgt tgcacattga
    22021 gtacgattaa aaaagtgata atggcaagaa aacttgctac tgcttgtaat aaaaaggttg
    22081 ttagtgtcat attagttcat caataccaag gcgacagaag ttcctgcccc taaagcgagg
    22141 gtaatgagca gggattcaaa catcttactc ataccagagt ttatgtggtt ggtcataata
    22201 tcacggaccg cattggtcaa ggcaatacct ggtacaaacg gcatgaccgc accagctata
    22261 atcaaatctg ccgttgaagg aaaacctgtg tagcgagccc aaaactgggc aattatccca
    22321 aagacaaagg ctccagcaaa ggctgtcaca aagggaattc ggataaattt ttccacatag
    22381 agggaaaagg caaaaccaaa taaggtcgcc actcctgccc caagtgcgtc gtagatattt
    22441 ccgctaaaca taactgaaaa gaaaggagca ctaaaggtcg cagccagagt tacctgcaac
    22501 ttagtatagg gaaggggttt ggcttgcaag gccgtcaatt gcttaaaggc tgtttctaag
    22561 tcaatctgcc ccccaactag ctgacgagaa atctggttca catcgcagac tttttcgatg
    22621 ttataagaag aggaggtcac gcgcttcatg cgcgaaatat tggtattttc aatagagaaa
    22681 aagatagcgg caggcatggc aaggacattg caatccacaa tcccctgcga atgcgcgatt
    22741 cgaatcatgg tatcttctac acgatggatt tctgagccac ttttaaggag aatagtcccc
    22801 gctagcataa tcacatcaat gacggcattt aattcttttg attcttccat gctttcctcc
    22861 ttttatcaac tccctctatt ctatcacaaa tccggactca aaaaaaatct ttgccatgaa
    22921 atcatgacaa agattgatta ctcattttga ttatccatct gcttttaagg agtagctgaa
    22981 gttgttttag gtttgtagat tgaaatcttg actctagtct tatttaggtc taccttttca
    23041 cctgctctag gactttgttc aacaaccatg ccttctacac tacctgcagg cgctgtcgtc
    23101 acttctacaa cttctatatt agcttcctta atcccaacaa tttgaatcaa attgttctta
    23161 gtaaactcca agctggaacc aatgtaactc ggcatggcaa cacttgtaac ttttttagct
    23221 actgtcaaga caatttgagt aggtttactc acatcataag tcgttccggc acctggactt
    23281 tgtttcataa tcgttcctgg ttcgctttcg ctggactctt cttcctctat cttaatcaaa
    23341 ttctcaggaa ccttcttctg cttgagttct gagattactt ctgtagagtt ccgtccaata
    23401 tagttcccta attgaatcgt cgtagctttt ttagctactg tcaaaacaat ttgagttgcc
    23461 ttgctcaagt cataggtcgt accttctggt agactttgct tcaagaccgt tccagcctca
    23521 ctctcattgg actcttcttc ctcaatttta atcaaattat ctggaacttt tttctctttt
    23581 aattccgcga taacatcaga agatttccgg ccgacataat tactaatttg gaaggattgt
    23641 ttgcctgatg agacaaccag attgattttc gttccttctt ttcgaccagt tccagcgcca
    23701 ggatctgtac ggataatccg cccttcttcc accttttcac tagcctctgt cttctcctca
    23761 ccaatctcaa aattggcttt tttgagcgtt gccttggcct ctgcaactgt ctgacctgcc
    23821 acatccggaa tggcaatggt tgcaggagtt ctggataaga tccaaataag agaagctgcc
    23881 accaatacaa ggctggccaa caaaatcagg taacgcatct taaatctatg ttttttcggt
    23941 gcttgtggtt ggtaagtttc ctctgtcaca gcctggcttg ggtttttgat tgatttgtgt
    24001 tctgtctgcg cttgaacctt aggaatagat gtcaaggtac tctgagaaac cttcggcaag
    24061 gtcttggtat ctgccttgct cgtttcatca aagattaact tactttcatt tctacgattg
    24121 taggacaagc tactagacaa gtccacatac atctctgaaa ccgatcggta gcgattggtc
    24181 aactttttag cagttgcctt gataataaca ttttctaaag cctgaggtac agatggattt
    24241 tctgcaataa cggacggcag gggtttctgg aaatgctgga gggcaatggt caccgcgcta
    24301 tccccgtcat aagggatatg gcctgtcaac atctcataga aaataatccc catggcatag
    24361 atatcactct gcacagtcgc cttagaacca cgcgcctgct ctggtgacaa gtaatgaact
    24421 gagcccaaca tcgagttagt ctgggtcaga cttgtctctg caaaggctac agcaatccca
    24481 aagtctgtga ccttggcagt cccatctggt gtcaaaagga tattttgagg tttcaagtcc
    24541 ctgtgaacaa ttcctcgagt atgggccaag cgcatagcca agagaatttg tcccatgata
    24601 cggacggctt cttcattaga aagaggataa tgttccttga tatagcgttt gaggtctagt
    24661 ccagcaacat actccattgc aagatactgt tgaccgtctt cctcaccaat atctgttatc
    24721 cgaacgatat gaggatggtc tagatctgcc atagctctcg cttcacgctg aaaacgagct
    24781 acagctatcg ggtccgtctg gtagttggtc ctcagaacct tcactgccac ttcttcccca
    24841 tctaagatta agtctttggc taggtaaaca tccgccatgc ctcctcgacc aatctgtttg
    24901 acaatccgat agcgtccggc aaaaatcttg ccgatttgga tcattcttca tcctcctcgt
    24961 tcatagaaac aagggcaacc gtaatgttgt ctaaacctcc tgcattgtta gcaaaacgaa
    25021 caagtgtctc cgttttatct gctaaaggaa tatcactggt tacaatatca cgaatctcac
    25081 tgcctgaaat catgttggtc aagccgtcac tattgagcaa gagatagtca cctgactcaa
    25141 ggataactgt cccaaaatca ggctgaattt catctttttg cccaatagac tgggtgataa
    25201 tatttttttg cggatgagct tctgcctctt ctggtgtcaa ttgaccagcc ttgagcaatt
    25261 cattaaccaa ggaatgatcg ctcgtcaact gatggtattc ttctccacga atcaagccga
    25321 tacgcgaatc accaatatga gcatagatag cctgattatc aataatagca aggacttcca
    25381 aagtagttcc catgcctctg taagcttcat cctgaccaag ctggtgaatc ttttgatttt
    25441 caatttctag gtaatgggcg aaccattcac gcacttcatt gactgtatcg atctgggtat
    25501 caacccaagc tacacccagg tctgtgaccg ccatttcact agcgatattc cctgcacgat
    25561 gacctcccat cccatcagct aaaataatca tggtacgtcc agctctattg acatagtggt
    25621 tgacatagtc ttggttattt gttcgtttct gaccaacatc tgttaataat gaaatttcca
    25681 tgtgtcagtt ccttcctaat ccgatatctt gcgaaattga ctgatgaaga atccatcact
    25741 tccatacaat tcaggtgtaa tgaggataca gccgtctttc atgatatcct tacattcatg
    25801 ttctagtttt acctgctcga actcgggatg actctctaaa aaggccttaa cgacttgaaa
    25861 attctcctct gagacgatag tgcaggtgct ataagttatt ataccacctt tgcctagtat
    25921 ttgacaaaca ctacctaata tttctaactg aatttcctgc aaggacgcga aatctgccgt
    25981 ttctttattg tatttgatat ctggttttcg gcgcaaaaga ccgattcctg aacaaggagc
    26041 atccaccaaa atcttatcaa aggaatcctg gtcaaaaaac tcatgcacct ttctggcatc
    26101 caatttttga gtttgaaccc gatcttcaac tcccagacgt tgggcatttt cttgaattaa
    26161 atccaacttg tggtcgtaca agtccagagc agtaacctga cctgtcgtaa gataagaggc
    26221 tatatgggct gttttcccac ctggagccgc acaggcatca agcactcgct catcaccttg
    26281 taaatcaagc gtcggagcaa ccagctgact ggactcgtct tggatggtaa tggctccatc
    26341 cgcaaacaaa ttatgccctg caaaatgccc ctgctcctta accagaccag tggttgctaa
    26401 aagggaatca ttcgcctcca acaaggcttg gatttcctct tttcgactta ggtctgttac
    26461 acgaatactg gctttgtttc gcactaacag gctttcaaag atggcttttg ctctctcctc
    26521 tccgtattct tccttgagtt tggcaactag ccaaactggg agagaatagg caatggagtc
    26581 acgcttgttt tttcgcttga tgctagcaat atctggccag ccttcacgca agatacggcg
    26641 aaggagggca ttgaccaatt tttcactgcc ttttttacga agtttggcca attccactgc
    26701 ttcattgacc acagcatgat ctggaatctt gtccaaatag cggagttggt aggcactcat
    26761 gagaagaagg acatagagcc agctgtctaa ctggtctctg tcttcgataa agtgggatag
    26821 gtaccattcc agagtcagtt tacgggctac cgttccatag accagctcgg tcactaagcc
    26881 cttgtctgct gccaaaagtt gactcccctt tagatgctta tttaaggcga tatttgagta
    26941 tgcttggttc acaaaaacat cctctagcac tgctagagct aaacttctag ccgtttctac
    27001 tttagtcacc aaatcgttct cctacagtca atgtacgtcc aactccgttg aggaaggaag
    27061 caatgtccat cttaggctta ccagctggct gcacttgttt gagggataga gccccttcag
    27121 ccgttgcgac aatcaattct ttcttgccga tagagagaat ctcacctgga tttccctgac
    27181 cttctactgg tagggcttca taaatcttaa agcggtcgcc cttaaggaaa gcatgggcaa
    27241 caggccaggg gttcattcca cgaatttggt taaagagttg acgattggtt ttgttccagt
    27301 ccagtttttc ttcctctggc tttatatttg gagagaaggt aacctgactc gtatcctgcg
    27361 gttcaggttt gatatcacca gcaatatagg caggcagagt gtccaaaagc aaatcacgac
    27421 caactagcgc caatttttca aacaaggtgc caacattgtc ctcatctgtg atcggaatgc
    27481 tgcgacgaga aatcatatct cctgcatcca tttccttaac catttccatg atggtcacac
    27541 cagcttcctc atccccttga atcaaggcat aatggatagg cgcaccacca cggtgtctag
    27601 gaaggaggga ggcatgaacg ttgacagcaa agtccatgct atcaaggagt ttgcttggga
    27661 gaaactgccc aaaagcagca gtcacaattc catctgctcc tagcttcata agttcttcca
    27721 tctctggact tccagataat ttttcaggtt ggtagataga tagtcctgct tccttggcag
    27781 cctgcttgac tggggtttct tggataactt ttttacgacc aacagcacgg tctggctggg
    27841 tcacaacggc tagaatttcg taacggtcat ctgtcaaaag tccttttaag actgttgctg
    27901 aaaagtcggg ggtccccata aagattagtt ttgtcatatc ttctccttct tataaaaatt
    27961 gctgcggctc atggtcaatg ctgagacgga gctcactatt ttcccgttct tgagtcaagg
    28021 ccaagacctg gttgagggtc ggccccagct catcttctaa acggtattta attaaaatct
    28081 ggtaatgata gaggttgtgg gtacgggcaa tcggttttgg cgttggcccc agaatgggac
    28141 tggtctctga caagcctgac cgcaaaatgt tcatgacttc ataggcacgt ttgaaaacct
    28201 cttcttcttt cttgtgagaa agggtaatac caatcgtgaa atagtaaggt ggatagccga
    28261 gttgtcgtct gattcccatt tcataggcat aaaagccttc gtaatcttga tccttggcaa
    28321 atcgaatagc atagtgctgc gaattgtagg actgtatcaa gacttgacct gctttttcag
    28381 cccgacctgc tcgacctgcc acctgagtca agagctggaa ggttctctca gaagaacgga
    28441 aatcaggcag attcaaggcc gtatccgcat ttagaactcc gactagggta acattgggaa
    28501 aatccaaacc ctttgcaatc atctgagtac caagtaaaat atccgcttcc cctcgcccaa
    28561 actggtcaag caaggcttgg tgactgcctt tctttcgagt cgtatccaca tccatcctca
    28621 aaatgcgagc ttggggaaag agttctgcta gctcatcata agccttctga gttcccgtcc
    28681 catagtaacg aatactgcgg ctcttacagt taggacagac ctgaggaata tccttcgaga
    28741 aaccacaata atggcagttc atagtcttgg tatccatatg caaggtcaga gaaatatcgc
    28801 agttgggaca agtatccacc gtcccacact cccgacacat gacaaagcta gaataaccac
    28861 ggcgattgag catgagaacc acctgctctt ttttaaccag acggtcttgg atagcctcta
    28921 gcaaaggagg cgtaaagttt gacgtctcat tttgtccgat atagtctcga aagtcaatca
    28981 cttgaacctc agggattgta gccaaaggat tagcacgttg ggttagacgt aagtgttgat
    29041 agacgccttt gccagcacgt gcccggctct ctaagctcgg cgttgcagat ccaagtacca
    29101 gagttgcttg attatactga gcccgtaaaa tagctacatc tctggcatgg taacggggat
    29161 tgctgtcctg cttataagcc acttcatgct cttcatcaat aatcatgaca cccagatttt
    29221 tcagaggagc aaagatagca gatctggcac caacaacaac ttgggcatcg ccacgctcca
    29281 ccttgcgcca ttcatcatac ttttcaccat tggataatcc tgagtgaaga atggctacct
    29341 tgtccccaaa acgtgctata aaacgctcgg tcatctgagg agtcaaggaa atctcaggta
    29401 ccagcaaaat agctgtcttg cccttatcca gggcaccttg gataatctgc aagtaaacct
    29461 cggtcttccc acttcctgta atcccttgaa gtagaaaggg aggttgagaa ctgccaatag
    29521 aactcacaac cgcatcacgc gcctgtcttt gttctggatt taactccaaa ggtctacttg
    29581 cttcaattcc ttcaaaataa gcagccgagc gttgaacttc cttttggact atggtaacag
    29641 caccttgatc cacaaagaag ttgacttgct ctcgcgagta ggactctaac aagctagcca
    29701 aggaagcgct ctctggatga gacagcagat aatctctcag ttccaacttt ttcttggcac
    29761 gtgtagaaat ctcaacacct tctaattgag catggtcaac ctcataccaa gactgggtct
    29821 tgaccttctt ttgatcgact gcctgatatt ccagaccaag caggcctttt ctagtcaaac
    29881 gcatcatttc agcttgcttg gcaaggtcta gtgaagaaaa ggctagcgaa tcttctgaac
    29941 caaacaggcg cactcgttct tcctgactca agccttccag aggatagaga atcttgtcat
    30001 agctagaatt cagaaatcct ggaagcatgg ccttgaggat agaaattttg taggagaaga
    30061 cagatttgcg taactcctca gccagccaga gttgttctgg cgtgagaaca ggagaaaaat
    30121 ccagcacctc tgcaatatct tttaaatctt gctccatctc ttctccatct gattgggact
    30181 ccaaaccaag aacaatccct tgaatcaggc gattcccctt accaaaaggc acatgaaccc
    30241 gcatcccaac ttccagcatt ccctcaaatt cctccggaat cctgtaacta tagggctggt
    30301 ccgtctgcat caagggcaca tctacgataa tcttagctag ggccatcgtc tcacctcctc
    30361 cttgtcagta cattcttgca atagaaaaaa taagattgag tccccccaac cttaaatttt
    30421 ttcaccatct tctttttctt tagcaatttg ctctttgatt ttcttttctt cttcttcttt
    30481 gcggcgtttt tcttcttcga tacggcgacg cactgcttca cgttttcctt ctggatctgg
    30541 gtgaattgta acgtttcctg attcgatttc ttctaaagcg cgaagagttg atttttcaga
    30601 cttaaaacct tgagttgctg gggcacctgc ttccaattcg tgggcacgtt ttgcttccaa
    30661 gattacgagt gaatattttg aaggaacctt gtcgagcaag gtatcaatag agggttttaa
    30721 catcatttgc ttgtacctat tttctaaatt ttatcgggta gttggagatt ttggtaacat
    30781 ctcctgatag tgaccaatga cacgatccac acagaagtgt tctgcttcaa tcacacattt
    30841 gacacgttca gcagctaggg gtacctgatc gttgacaatc gcataatcat actcacgcat
    30901 gagggcaatt tcttccttgg ccttttcgat tcgttgggca atcacttctg cactatctgt
    30961 tccacgacct accaagcgat cttgcaattc atccaaatct ggtggtgtca ggaagataaa
    31021 gacagcatct ggaacctttt tcttgacctg aagagcaccc tgaacttcaa tttcaaggaa
    31081 aacatcgatt cccttgtcca aggtttcatt gacataggtc agaggagttc catagtagtt
    31141 gccgacatat tctgcgtatt ccaacatctg tccttgacga atcagctctt caaattcttc
    31201 acgagtacgg aagaaatagt caacaccgtc cacttctcca ggacgttgtg cgcgtgtcgt
    31261 catcgataca gaatattgaa attggttttc agaactctca aaaatctctc ttctaaccgt
    31321 tccttttcca acccctgaag gaccagaaaa aacgattagt aagcctcggt ctgccattgt
    31381 gtctcctttt agtcaatctg tgaaataaca tttctctaga ataatggcaa aaagccagat
    31441 tatcctttac agtctttcta tctagtgtaa caaaaaagca gtaatttttc aactgctctt
    31501 tcttatttat ttagcataat ctactgcacg aagctcgcga atcacggtta ccttgatatt
    31561 tcctggataa tcgagattgt tttcaatttt cttacgaact ttgtgagcca agattgtgac
    31621 tttgtcgtcc ttgatttttc ctggattgac catgatacga atttcacgtc ctgcttgaag
    31681 ggcaaagcta gtttgcactc cttcaaagcc gttagcaatt tcttccaaat catggagacg
    31741 cttgatgtag ctttcaagag actcactacg agcacctgga cgggctgcgc tcaaggcatc
    31801 tgctgcagcg acgataactg ctatcacgct ctcagcttca acatctccgt ggtgactagc
    31861 aatcgtattc accacaactg ggggttcctt gtacttacgg gccaattcca taccgatttc
    31921 aacgtggcta ccttcaacct catggtcaat ggctttcccg atatcgtgaa ggaatccagc
    31981 acgacgggca agagccgcat tttcaccaag ttcgctcgcc atgataccag ccaacttagc
    32041 aacctcaatc gaatggcgca aaacattttg tccatatgaa gtacggaact gcaaacgtcc
    32101 cataatcttc atcaagtctg gatgaaggtt tggcgcacca atttcatagg cagcagcctc
    32161 accgtattca cgaatcttat tgtcaatctc ttgacggttt ttctcaacca actcttcgat
    32221 acgagctgga tgtatacgac catctttgag caacatttcc atagtcatac gggcaatctc
    32281 acgacgaatc ggatcaaatc ctgacaaggt caccacttct ggtgtatcgt cgataatcac
    32341 atcgacccct gtcaaacttt caaaggtacg aatgttacga ccttcacgac caataatgcg
    32401 tcccttcata gtatcgtctg gcagatgaac tgttgagttt gttgactccg ctacatattc
    32461 accagcgata cgttgcatag cttgaaccaa gatgtccttg gccattttgt cagaacgttc
    32521 cttgacctct tgctcagctt cgcgaatgcg actggcaatc tccctggtca agttttcctc
    32581 tgtctgagcc aagataatat ctcgtgcttc tgcctgagac agagcaccaa tacgctctag
    32641 ttctgcttct ttttgtcttt cgacttcctc taattgctct tcacgcgcat caaggttttt
    32701 cgctctatca gaaatacttt gttctttttg ttcaagtgtt tgttctttac tcgtcaaatt
    32761 gtcgtcctta cggtcaaggc tagtagctct ctctgtcaaa cgactttcga tttgtttgag
    32821 ttcttgacgt tctgatttga attcagcgtc cacttcttca cggtattttc tggcttcttc
    32881 tttggcctcc aatagtgctt cttttttaag agacttgctt tcacgtttgg cttcattaac
    32941 aagtaaatcc gcttcacgct cagcttgtcc acgtaaatta gttgcttctt gttcagcatt
    33001 taaaagcatc aactctgcag cttcctgaga tgatttcatc ttagctgaga tgctgacata
    33061 tccaatgact aaaccaatga tgacggcaaa aacagcaatc gcaagcgaca tgatttccat
    33121 gtttttacct cattttattg ttattccgaa tgacatacat tcttttacat tctaccataa
    33181 aaaaagaatt taaacaaacc ttaaatggat atcgctaaca tccgcattat cactatcata
    33241 gttatcattt acagatataa agcgaatacc tttttcagga aatatctttt gtaagtactt
    33301 tcctgactcg atataatctc tgccgaaacg agataaatct tttaccataa tgatagaaaa
    33361 ctttccttta ttcaggtcat caatcatatt cttaaaattt ggtcgctcaa aattagaacc
    33421 actatatcca tcatctacat attcatagga taattcaata gatttctctt ctacctccaa
    33481 aaagcaaaaa ggataaattt cccctacact ttaatagtga aaatttatcc ctcttggtaa
    33541 gctcttttat taattttttt gataaagaaa acgcacattt tatttaactg gtgctgaaat
    33601 ctttataata aaattttttt ggttctttct agaataatga tattaagatt tttcatatat
    33661 cttatatatt cttcttctgt gctagcaatc aaaatatctt ctttatctaa aaagacaacc
    33721 tgattgttct ctaaatctga tttaattaaa tctataattt tattttgctc atatataaat
    33781 ccttctaact tgaaaaactc gacaaagttc tcaaatccat ttttacaatt atcatcacca
    33841 gaaaatagtt caaaccattc atggtaattc tctatagcat aacctatttt tgtattttta
    33901 ttttccacaa accattcttt tatagcatat agtgttaaat caaaacgatc ataatatcct
    33961 ttttctccac ctctagcctg attaacggtt tctaattttc cacctctagg gaaaagaatg
    34021 tgtccaccta ttgttcttga aatactcaaa tgatctaaaa ttattctgtc gtttaatcct
    34081 gcctcttgtg cccaataaat agaggctcct atataatcac ttgataataa atacttatcc
    34141 ttatcaataa ataaagtata ataatctcta tttccatagt tttggcattt attacataca
    34201 gatgttattt taagtttttc ttttgaatca tcatcaaaaa acatcttaca taaatcatcg
    34261 tacaacgcct tactacatac atcaggatcc tctctattat ctaatgaaaa acctttggga
    34321 aaataaggat ataaatcaaa tagataattt ttaaacttca tatttattat tctccattaa
    34381 atctttttag gaaatttaaa gtcaaatttt cctccaagca cacccgcact tactcccgca
    34441 actactacaa gtgttgtact aattgttcct attttcttca cgccactgtt tagctctttt
    34501 gttaaataaa acaacattga tcatatctgc ttcacttaca tacttgtaag acaactgttc
    34561 gttggtaaga tcttttaaga gatattcttt gattgcatct gtatgaattt tgtagttaat
    34621 cttagaaatt tctctattca aattccagcc taatgatagc ttagaatttt aatctgactt
    34681 aagtcttttg taatcctgaa ttacatacat cttaaattca gcagaaatac ataaagcaaa
    34741 ttcaaaggca atatctgtat gtgcaaatgc accaccatat cttccacctt ttgagataat
    34801 tccgattgct ccagttttct ctacccattt cttaggagac aatgtaaatg aattatatcc
    34861 agcttccgat ttaattcggt cgaattcgac cgaattgaaa ttcatgttat ttaagctttt
    34921 ccataaacca agaaactcaa ttgtatcttt tcttctcatc caatttttaa ttacatcact
    34981 cgatacttat ccgaacgata agctccacgt aaggtgttcg caatcgacca aactgcattg
    35041 actacatttg aaatctgaac atcgttcgac tggaatatcg gtagtttttc tttaaaatta
    35101 gacatttgct tcccctgttt ttatgattta caattctctt cattatacca caaaataggc
    35161 gctttgtcaa ctgtagtggg ttgaagtcag ctaagctcga gaaaggacaa atttcgtcct
    35221 ttcttttttg atgttcaaag cgataaaaat ccgttttttg aagttttcaa agtttcgaaa
    35281 accaaaggca ttgcgcttga taagtttgat gagattattg gtcgcttcca gtttggcatt
    35341 agaatagtgt agttgaaggg cgttgataat cttttcttta tctttgagga aggttttaaa
    35401 gacagtctga aaaataggat gaacctgctt aagattgtcc tcgataagtc cgaaaaattt
    35461 ctctggttcc ttattctgga agtgaaaaag caagagctga tagagctgat agtgatgttt
    35521 caagtcttgt gaatagctca aaagtttgtc taaaatctct ttattggtta aatgcatacg
    35581 aaaagtagga cgataaaatc gcttatcact cagtttacgg ctatcctgtt gtatgagctt
    35641 ccagtagcgc ttgatagcct tgtattcatg gaactttcga tccaattgat tcatgatttg
    35701 aacacgcaca cgactcatag cacggctaag atgttgcaca atgtgaaagc gatcaagaac
    35761 gattttagca ttcgggagtg aaacagtctg ggagactgtt tcagcctgag cctagaaatt
    35821 tgaaagcgaa gctgtttagc caagtcatag taagggctaa acatatccat agtaataatt
    35881 ttgacgcgac atcggacagc tctatcgtag cgaagaaagt gatttcgaat gatagcttgt
    35941 tttcttccct caagaacagt gatgatattg agattgttaa aatcttgcgc aatgaagctc
    36001 atctttccct ttgtaaaagc atactcatcc caagacataa tctcaggaag acgcgaaaaa
    36061 tcatgtttaa agtgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgtacttgag
    36121 tacggcaagg cgacgttgac gcgatttgaa tttgattttc gaagagtatt attcgtaaaa
    36181 aatctcaaaa agtccacctt tcggtagact tagtttgttt ctattctaat cggcactctt
    36241 ccaaaattct gttgtgctat acttagattt cctagttggt aaatctggtc tgctttttgg
    36301 gtcatagcat cccaaggttc tttgccaatt cggctgacta gactgacctg acctttcaaa
    36361 gacttgagat gttgcctgcc tttttcagta aatccaagga catgaatggc ttctggcaag
    36421 acattttctc tagcctgcgc caagatatag gacaagaggc gtctgacacg cgccttggtg
    36481 taacgtttgg tagtcactaa ctcgaccaat tcttccacag actgggctgt tttaatagct
    36541 tctttaatgc gcacagccat ttcttgattg acctgataga tggtggttag gtcgggattt
    36601 gacaagattt gatagcggag caagggaaaa tagtcttccc agatcacctt actggcctgc
    36661 tcaaataggg caacagaagg cataaaacgt tctaagaaat cttggtcctt ctgatgttga
    36721 cggagggctg tcgccgaggc aaagtccaca tctttattca cagaatggta acctgccccc
    36781 tgacgctgaa tcggatgcag cttgatattc cgtcctgcaa ccgccttggc ataggccaga
    36841 gcaagaacat gattgggggt attacctgaa aaatcaagac cagcaaattc cttccacata
    36901 gcttgggttt tctggggata ggaaagggaa tcaggcagat tttccacaaa tttctccatc
    36961 tcagtacctt tctctgtgta taagtcagcg attttctgat aatctcgaac ttcctctgtc
    37021 ccaaaaacta gactatcaat gcccaagcga tccaagatat ccacagctcc ttgaccaaag
    37081 aaatcagctg cctgaacact gactaaaaag ggcaattcca ctaccaagtc tgcgccattt
    37141 tccagcgcca tctgggccct tgtccactta tccacaatag caggctctcc acgctgcatg
    37201 aaattccctg acatggcaac aattttcagt ccctctgcct gatccagcag gtatttatgg
    37261 ccattatgaa aaggattgaa ctctgcgata atacctgtga tggtcatgat gttctcctac
    37321 ttctgcgcca caaaaaacca acgggtgcta gtttctgttg gctccttatc ctcaaagtct
    37381 gcatagagtt tgaaggactt aaatccagcc tgttccagca agatatcata ggtcaagatc
    37441 tcataggtcc tctcctcatg tacttcatcg tggcgactaa aggaaccgtc agcctccttg
    37501 ataaagaaag tcagctcatg cacgatggag tgaggagctt cgtcctcata tgtatcccaa
    37561 agcatggcaa aatcttccgc attttcatgg taggaatagc cagggaatac ttcatctgtc
    37621 tggtaggtcg agtgcacgtc aaagatgaaa actccctctt cattcagcgc attgtacacg
    37681 tccttaaaga cgtcccctac ttccacctca tcctgcatat agcagataga gtccgaataa
    37741 cacgtgacaa aatcgtattt ccctgccttg gacaaattca gcatattacc ttctataaaa
    37801 gcaatctttt gcttggctga agttgctctc ttctccgcaa tcttcaacat atccgcactc
    37861 aagtcaagtc cagtcacatc aaaaccagcc tgagagaagc gcactgattg aattcctgtc
    37921 ccacaagcca attccaagag tttctttctc tccttggtct taggcaaatg acgcagagaa
    37981 aaattcgtcc atttgtcgta taaactatcg tccatgaccg catcatagac cgccgcaaag
    38041 gtttcataag tcgccataaa acatgatacc aagtccgccc gtaattcgat agaaaattag
    38101 gagccttacg atggagccga gctccaagga aggctatcta ttttccgaga attacaggac
    38161 gggttcaaat cctttctaag atacaaagag ccttaaaagc aaagagtaca taggaaactt
    38221 tcttccctat cgtcagatac aaagaaagtt actttttatc tcagctttta gctcgtgttc
    38281 agtttcgaaa tgaaacaaac acgaggccct ttacctttct atcaattttt ctaaaataag
    38341 caaagaaacc cagttgacta caactgagtt catcttctaa gcaagagctt ctgaaatatc
    38401 tactgaattc gcctcatgcc atagcttctc tagattataa tgggcacgca tttcttctga
    38461 aaagatatgc acgacaacag caccgaggtc cagtaagacc cagcctccag ctgcatcgcc
    38521 ttcgacatgg ctacctttaa agcctgcttg agctactttt tcacggatat tagctgcgat
    38581 agcgtccaac tgacggctat tcattgagct agtgatgaca aagtagtccg tcacactagt
    38641 caaatcttgt acatcaagtg cgaggatatc ctccgcacgt ttctcatcag ccgctttcac
    38701 gactagttct agtaattctt tttcgttcat ttaatcctct ttttagaaaa tatgtttgta
    38761 atctagaaca tctgcaaagc gctcctccca aatgtcctca taaaattcat taatcgtttc
    38821 tgctggaatg tcatccccat caaaggttgt gacagcacct tctggaacaa taagctgata
    38881 gccatattca aaggcaacct tgacagaggt atccacacaa tattctgtct gcataccaca
    38941 taaaactaat ttttcaatcc cctgcttatc caagtattct tttaagccag tttctttgaa
    39001 aatactgtta tacttcttct gaaagacctt ttcagcaggt tttcgattta aaagcgcaga
    39061 taactgccaa tcttctgatg tttgagcttc agagttctca atatgttgaa catagataat
    39121 ttcaatattc ttgcttctag cctggttttg taaataagaa attttttcca atagactttt
    39181 tgtctggaac ccagtttcta ctaaaacatt ctgaacatca atgattataa aagccgtctt
    39241 catttagtcc tctttcaaat agtgcacaaa ggcgttatag gtttcaaggg tttggggata
    39301 gatggggaat ccctgatgag ctagatactc cacggtacga gctgtttcgt aggccaccgc
    39361 cttattgagc gatagacttg caatctcacg cgccacatcc actccaggaa atgcccgatt
    39421 gtgctcgata tagtctgcga cgtagatgac cttatctagg tctgtcattt gaccagctcc
    39481 gactgtatga atttcaatgg ctcgcagaat ttcagaatca tgcaaatcca aatcttcctg
    39541 aattttgtaa attccgacca taccatgcca gacattgttg ccccagtttt tgaggtcagg
    39601 gtctagctgg taacggtcaa tcaaggctag aaattcctga tctgacaact ttttagcata
    39661 gtcatgaaga agacctgcta gacttgcttt ctcaacatct acaccaaagc gctgagctaa
    39721 ttccatagcg gcacgctcca cacctagaca atgggttaga cgtttctcag gtagaagctc
    39781 tgccattttt tccaacaagg cctcacggga gcagttgata tagtcttgat aggacatcag
    39841 tagagcccct ccttctcgat gtagtctagc actggctgag gtaggagaaa gttgggtttc
    39901 cgaccttggg caaggaagtc ccgcaccatg ctggacgaga tatccatgag cggtacgtcc
    39961 acccagataa ctggatagga agtccctacc ttgtagcgtg gacgctgaac ccccacaaac
    40021 tgaaccatgt caaccagttc atcaattcgg taccacttag gcagatagtc aaccatgtcg
    40081 gcaccgatga taaagtaata atccgtatct ggattcttct ctgtcaaaat cttcatggtg
    40141 tcgtaggtgt aggaaatacc cttgcgctcc aactcaatgg tttcaatgac taggccgtca
    40201 attccctcaa ttgccaactc aagcatcttg agacgatggt gttcagggat ggtttccttt
    40261 ttatcaacgt gaggaggttg gtattcaggc atgagcagaa cttgatccag tcccaactgt
    40321 tgccgtactt gatccgcaac aataagatgg gcattgtgaa cagggttaaa attcccccct
    40381 aaaatcccaa cttgtttgcg ttttttctcc ttgatttctg gctccaactc taccttggta
    40441 aagggagtca atagttcgat tgtcataggc tagtcccctt tatttctcta tgaaaacagt
    40501 tatttggagt ttcggtctta gatttctttg actttcttag aaatcttgcg attttctttc
    40561 ttgctagatt gtttaaacaa aatcaagatg cgtcctattt tttggactgt atccacaccg
    40621 atttcttctt ccaaaatttc agctacttcg tggatgtttt catctgtgtt ttgtaagaga
    40681 gtaaccttga ttaattcacg cgcatcaaga gcttgacgga cgctggtttt gatttggtcg
    40741 ttgagtccat ttttcccgat ttggatgata ggtttgaggg tgtgtgcctg gctgttgagg
    40801 aaggcacgtt gttttgatgt taatgacata attttcttcc ttgttttttg atagttattt
    40861 taggtggtga gggacggtcg gaactaattt tccaaagatt tcatctttga aaaatggatt
    40921 tcctgacctc acaattgagc cttggtctca attgtgcccc ttgccaatct acagattggc
    40981 aatcacacca cggcaataac tatcgctata tgagctcact ttgttcgctc agcgattttg
    41041 ttttaaataa ttgcttttcg tgtgacgacg gcgacgcctt ctggtgccca gacggcgact
    41101 tttgctgtgc ctgttacacg aatccagcct aggcctgaga tgactaggtc tgtcttatct
    41161 ttaatggtaa agacatgctg gactagcctt gggaaatctt ctttttcctt gctatttggt
    41221 ggtgtcagaa gagttcccag gtgcttatcg tagaaagcac tagctccttc aagcttgcta
    41281 cgatggagtt tgagttcatt gtcaaagaaa gcagtaaatc cttgcttttc tcctgttata
    41341 aagtcaaagc gtcccaaacc acctaaaaat agggtttgct caggattaag ctgataggtc
    41401 ttaggcttga tttccttttt aggactgaca tacttgaggt ttttggccgt caaatagtga
    41461 gccatctggt ggcggtggat aattcccggc gtatcgtaaa tataagatcc gtcgtcaagc
    41521 ggaatctcta ttttgtccaa ggttgtccct gggaagcgtg aagtagtgat gacattctga
    41581 tcacccgtga tttcttggat aatagcattg attagagttg attttccaac gttggtcaca
    41641 ccgaccacat agacatcgcg gcccttacgg tagtgttcaa tcttgtcaat gacttcctta
    41701 atggcatgtt tattttgtgc tgaagttagg accacatcga ctggacgaag accttcttca
    41761 tgggcacgtt tcatgagcca ctggctaatc ttaccagact taactgactt aggaaggata
    41821 tcttttttat ttcctaccaa gaggacatca ttgcccgaga cgaaacgtgg taaacctggg
    41881 atgacagatc cattaaaatc aaagatatca atgacattga ccactaaagc atcactgtct
    41941 cccacctcgt gcaagagctt gaggaaatca tcgttcgtca actggacatc tgtgatttca
    42001 ttgtagtggc ggagacggaa acagcgttgg caatagactt cgccagtctc caaacctttt
    42061 tcaagtgccg actggggggt aaaaccaaga ccagctttat ctgtcgtctg aatggttgct
    42121 ccacaaccaa tacagagaat ttcttccata gttaaattcc ttttttatat gtaatcggtc
    42181 cgtacttttc agtgattttt ctcataacac gacgctcacg agttcggtta atctgcgttt
    42241 tgattgagtc atgttggacc aagggtttga ctaaaattga ccgaatccct gcacggtggg
    42301 ctgctcgtat atctgtcatg agctggtcac caaccatgac cacttccttt ttgtcatagt
    42361 ggaattcctt catggcacgg tcaataccaa atgtgaaggg cttcaaggcc cagtaaacgt
    42421 aatcaatccc aaatttctca actgctcgtt gaacgcgttt tttggtgtta tttgacacta
    42481 cgataatgcc aatacccgcg tcccgaaggt catgtagcca ttgcttcatc tctggcgttc
    42541 catcagggtt gttccaagca atgagggtat tatccaaatc gaccaaaaca gccttgattc
    42601 cctgcgcctg caggcttggg actgtcagat catagactgc ttccacagca aaatctggta
    42661 tataattttc aatcgccatt ctggctcctt ttcttaactt tttttcgcaa ttttccttag
    42721 taacaaggat aaaacaatcc acaaacctgc actagccaaa ctgatataga gccaagcatg
    42781 gggcttatct gttaaaggta agggaacatt cattccgaaa aagcctgtca cgactgccaa
    42841 aacagctagc aagactgaaa tgatagtcaa ggttgtcaaa ttgtcattca gattattgtt
    42901 tagaatattg ttgtaagagg ctgaaagctg ctgtaaaatc tgagagatta ggtctgtcat
    42961 ggataccagc tgatgagcct caatcatggc atcatcaaac tgttctctct caatctcatc
    43021 aaaactacga tacaaggcat gaccttgaat atgctctaac aaaatccgat tttgtttggc
    43081 agctgccgtc agataaacca taccagtctc caaatcagac agggcaaaga ggtttttctt
    43141 ggtagttcgc tggcgcaaga ggtcattgac ctcatcccta ctcttgtcca tctgctcaat
    43201 gacaggatag taggcattgc tgatgatttc cagactggca aagagaaact tataaatcga
    43261 aagcgtgtca tggttctcca gataacgagt catctgttca atgacatagg cgttcttggt
    43321 attactaatg gtaatcaggc gacgatgctc gacaataaag gtcatgggaa aagtctcata
    43381 gtaggccttg tcctttttta cgtctaggac attatagata aaggtaaccg tcccactttc
    43441 acggtggtag tccatgtggg cgcgctcgtt tctatccagt gcgtattcaa tggtttcctt
    43501 gtccaaaccg taaatttcag aaaggtcttc tagtttattc aactttccta ggtctaggtc
    43561 tatccaggta caaccattgc ccaactgctt ttctaaaacc atcttttctc cttattaaac
    43621 tccctctatt gtaccacaaa ttacttaaaa taacaggtct agtctgtgcg tgagaaattg
    43681 ctaacaactg tgatatttcg gttagggaca aagtgaaggg cttgctcctc gctacgaagc
    43741 tgtgtcgtac gaattcccac actgacaacc ttacccgata cagtaatcgg tccatttgtc
    43801 agaacgacct catctcccac atccagttga cgttcaaaga ggatgaaaaa gccattgatg
    43861 acatcagaca gaaagccttg ggctcccata ccaatcgcta ccccagcaat accagctcca
    43921 gccagcaaac tagaaactgg caaacctaaa atcgacaaaa tgcagtagag taaaaagaaa
    43981 tatagcgtat aattaaacac attttctagt aaacgtgaga tggttttttg gcgtccgaca
    44041 tcatgacgag acatttttag agaaggtttg acaattctct gcaccatggt atgaagcatt
    44101 tttttagcaa tataaaatac aatcaaaagc agtaaaagag aaatgacctt ggttagaata
    44161 ttctcgataa tggttgtcac atctagcttt tcaatataag cctgaataaa tttttgcata
    44221 taaaactcct ttatttcatt ataccatatt ttcatcagtc tcattctcca taaatattca
    44281 aaaaatagac agaaaattct tgattttgtc tatcatttat actataatca taatcactac
    44341 acaaaaagga gattattatg aaaagaatca ttcatgcttg gaataaggca agccttgtca
    44401 agcgtatctt gattggtatg ctttgtgggg aatcctagga ctgacccttc ctaatctctc
    44461 agggattggg ctactcgggg atttattcgt tggaggtctg aaagctgttg ctcctatcct
    44521 agtctttgcc ctcgttgcca atgccctttc ccaacatcaa aagggacaag atagcaatat
    44581 gaaaactgtt gttttcttgt atatcctatg atagggactt tcgccgctgc tcttgtagct
    44641 gtactagcaa gtttcatcgt ccctattgaa attaccctaa atagtgccaa tactgaaatt
    44701 gcaccaccag atgggattgg gcaggtcctc agcaacctct tgctcaaact ggttgacagc
    44761 ccagtcaacg ccctgcttac tgctaactat attggaatct tatcttgggc agtcattttt
    44821 ggaatcgcta tgagagaagc tagtaaaaat agtaaagaat tgctaaaaac tatcgctgac
    44881 gtgacttcta aaattgtcga atggatcatc aatctggctc catttggaat ccttggtctt
    44941 gtttttaaag ccatttctga caagggagtc ggaagccttg ccaactacgg tattttattg
    45001 gttccattag taacgactat gctttttgtt gcccctgtgg tcaacccttt gattgccttc
    45061 ttctttatga gacgcaatcc ttactctcta gtttggaact gcctccgtgt cagcggtgtg
    45121 acagcctttt tcactcgtag ttctgcgact aacattcctg tcaacatgaa actctgccat
    45181 gaccttggac tcaacccaga tacctattct gtttctatcc cactcggttc tactatcaat
    45241 atggctggag tagcgattac cattaacctt ttgacccttg ctgcagttaa cactcttgga
    45301 attcctgttg actttgccac agcctttgtc ctcagtgtgg tagcagctat ctcatcctgt
    45361 gatgcttcag gtattgccgg aggttccctc cttcttatcc cagttgcttg tagccttttc
    45421 ggtatttcta acgatattgc catacaaatt gttggggttg gttttgtgat tggtgtcatc
    45481 caagactcat gtgaaacagc ccttaactct tctacagatg tcctctttac cgccgttgcc
    45541 gaatacgcag caacccgtaa aaaataactc atcaaggcaa gcctgctcat gtcttgtctt
    45601 ttacgctttt attctaactt attaggaaat tcttatgtct attagccaac gtacgaccaa
    45661 gctcatctta gctacctgtc ttgcctgcct gcttgcttat tttctcaatc tttcgtcagc
    45721 agtttcggct ggaattatcg ctctcttgag cctatctgat acgcgtagaa gtactttaaa
    45781 actggctcgc aatcgtcttt tttctatgct tctagctctg gctatcggtg ttctagcttt
    45841 tcacttgagc ggatttcata tctggagtct cggcctctat ctggccttct acgttccttt
    45901 agcctacaag atgggctggg aaattggcat cacaccaagc actgttttgg ttagccatct
    45961 cttggttcaa gagtcaacct ctccagacct tctagtcaat gaattccttc tctttgctat
    46021 tggtacagga tttgccttgc ttgttaatct ctatatgcct tcacgagaag aggaaatcca
    46081 gcactaccac acgctggtgg aagaaaagtt aaaagatatc ctccagcgct tcaaatacta
    46141 tttatccaga ggagacggac gcaaccgagc acagctggta gcagaattag acacgctttt
    46201 gaaagaagcc ctcagactgg tctatttgga tcactctgac cacctctttc accagaccga
    46261 ctaccatatc cactactttg agatgagaca gcgacaaagt cgtatcctga gaaacatggc
    46321 ccaacagatt aacacttgtc accttgccgc cagtgaaagc ctgatcttag cgcaactctt
    46381 ttcaaaaatt gcaggtcaac tgagccagac caatcctgct tctgatttgc tagatgaaat
    46441 tgaacgttat ctggaagtct tccggaaccg cagtctgccc aagacaagag aagaatttga
    46501 aacccgcgcc acccttcttc aactcctacg tgaagccaaa accttcatcc aagtaaaagt
    46561 tgatttttac caaaaatata gacagtaaaa aataaaacca ctaaaaaaca gagcttgcca
    46621 gcattcttga aaagtagtat aattattgca tgcgcaatca tcttgtgacg cagagactgc
    46681 ccgttaatgg actttcttct atttatgact ctaaaaagaa aggagacact atgacctatt
    46741 tggaaaaatg gtttgacttc aatcggcgtc agaaagaaat tgaaagtctc ttggaagaga
    46801 ccgttgccca acagagcgag caaagtctga ccttgaaaga gttctacctg ctctactatc
    46861 tggacttggc tgaagaaaaa tctctacgcc agattgacct gccagataag cttcatctga
    46921 gcccgagcgc agtttctagg atggtggctc gcttggaagc taaaaattgc ggtctactca
    46981 gtcgcatgtg ttgccatcaa gatagacgct ctagttttat ctgcctgaca aatgatgggc
    47041 aaaagatact ggcctcgcta caaaagactg tcgaagaaag cttggaagca ggtttggatt
    47101 tcttgattta agatgatttt agaaaaagtt gcgtgcgcaa tcatttttct tgacattctc
    47161 ttttataagg agtaaaataa agttagcatt aaacaaagga gttttaaata tgattgaaat
    47221 tacctatata gatgccagca agaacgaaag aactgtgact ttcgagtctt atgaagactt
    47281 tgaacgttcg caacaagctt gccttatcgg cgtcgcagac tactaccctg tccaaaaatt
    47341 aacttacaag ggtcataatt tggactacca tgggacttat ggagatatct tcttctatct
    47401 catgaaacaa gatttaagcc aatataacta aaaaaaggag aaatacaatg gcaaaagcaa
    47461 ttacagatgc aacattcgaa caagaaacaa aagacggttt ggtcttagta gacttctggg
    47521 caacttggtg tggtccatgt cgtatgcaag gtccaatctt ggacaaattg tctgaagaac
    47581 tttcagaaga tgtcttgaaa atcgttaaaa tggacgttga tgaaaatcca aacacagctc
    47641 gtgcttttgg aatcatgtct attccaactc ttctcttcaa aaaagacggc caagttgtca
    47701 aacaagttgc aggtgttcac acagcagaac aaatcaaggc catcattgct gaattgagct
    47761 aatcaaacga gagaccaagt actttctttg gtctcttttt tcttgccctt tgccattttt
    47821 caaaaaatat gctagactat agtagattga aactagaata gtacacctct acttctaaaa
    47881 cattgttaga aatcgattta actgtcctga tcgatttgtc ctgttcttat ttcattttac
    47941 tatataagta gaatattacg atgtttggga tatgccatcg ctaaaaaaac tcgatttggt
    48001 attttttagc tccctaatag gagctttttg catgctctga acatttccca ttttggaagg
    48061 agtactatga aacgtcaatc agccttggtc gtctttagtg gtggtcaaga ttcaacaacc
    48121 tgccttttct gggttatgca acactatgaa acagtcgaag ctgtcacctt tgcctacggc
    48181 caacgtcatc acctcgaaat tcaaattgct agagaaatcg ctaaggaaca gggcattcgt
    48241 caccatatcc tcgatatgtc tctgctggga caaatcactg ctcagccaga ctttgcgacg
    48301 attcatattt cctacattcc tgacaagctc tgtgtcgagt caaaatccct caaactatat
    48361 ctatttagct accgaaatca cggagatttc cacgaaaact gtatcaacac catcgggaaa
    48421 gacttggtca acttgctaga ccctcgctat ttagaagtct ggggaaaatt cactccgcgc
    48481 ggtggcattt caatcgaccc ctactacaac tacggtaagc aaggaactaa gtatgaggac
    48541 ttggcagaac aacgcctctt ccaacacgac ctttatccag agaaaattga caaccgctaa
    48601 agtcatactc aatgaaaatc aaagagcaaa ctaggaagtt agccgcaggt tgctcaaagc
    48661 agtgtttgag gttgtagata aaactgacga agtcagctca aaacactgtt ttgaggttgc
    48721 agatagaact gacaaagtca gcttaaaaca ctgttttgag gttgcagata gaactgacga
    48781 agtcagctta aaacactgtt ttgaggttgc agatagaact gacgaagt
//
LOCUS       DAVKBK010000010        45535 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVKBK010000010 DAVKBK010000000
VERSION     DAVKBK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.010"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            529..981
                     /locus_tag="VWX69_000622"
     CDS             529..981
                     /locus_tag="VWX69_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9192008.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKAGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1000..2337
                     /locus_tag="VWX69_000623"
     CDS             1000..2337
                     /locus_tag="VWX69_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU9192009.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2416..3300
                     /locus_tag="VWX69_000624"
     CDS             2416..3300
                     /locus_tag="VWX69_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9192010.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWIINGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3300..4133
                     /locus_tag="VWX69_000625"
     CDS             3300..4133
                     /locus_tag="VWX69_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9192011.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4151..6244
                     /gene="nanB"
                     /locus_tag="VWX69_000626"
     CDS             4151..6244
                     /gene="nanB"
                     /locus_tag="VWX69_000626"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU9192012.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6256..7359
                     /locus_tag="VWX69_000627"
     CDS             6256..7359
                     /locus_tag="VWX69_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9192013.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7533..8231
                     /locus_tag="VWX69_000628"
     CDS             7533..8231
                     /locus_tag="VWX69_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU9192014.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8250..9767
                     /locus_tag="VWX69_000629"
     CDS             8250..9767
                     /locus_tag="VWX69_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9192015.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALAVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9892..11220
                     /locus_tag="VWX69_000630"
     CDS             9892..11220
                     /locus_tag="VWX69_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9192016.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11472..12338
                     /locus_tag="VWX69_000631"
     CDS             11472..12338
                     /locus_tag="VWX69_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9192017.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAIMIAIVSF
                     VQFKVLGNDVEY"
     gene            12354..13193
                     /locus_tag="VWX69_000632"
     CDS             12354..13193
                     /locus_tag="VWX69_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9192018.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13465..13917
                     /locus_tag="VWX69_000633"
     CDS             13465..13917
                     /locus_tag="VWX69_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9192019.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNRFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14014..14358
                     /locus_tag="VWX69_000634"
     CDS             14014..14358
                     /locus_tag="VWX69_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192020.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVTALIGRYIKLGTY
                     AVKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14645..15289
                     /locus_tag="VWX69_000635"
     CDS             14645..15289
                     /locus_tag="VWX69_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9192021.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15458..16375
                     /locus_tag="VWX69_000636"
     CDS             15458..16375
                     /locus_tag="VWX69_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU9192022.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTSSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTAAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEDDRPVVEAAAALIRETKERFL"
     gene            16393..17277
                     /locus_tag="VWX69_000637"
     CDS             16393..17277
                     /locus_tag="VWX69_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9192023.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17293..18144)
                     /locus_tag="VWX69_000638"
     CDS             complement(17293..18144)
                     /locus_tag="VWX69_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU9192024.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18344..20401
                     /gene="pbp2b"
                     /locus_tag="VWX69_000639"
     CDS             18344..20401
                     /gene="pbp2b"
                     /locus_tag="VWX69_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU9192025.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20412..21008
                     /gene="recR"
                     /locus_tag="VWX69_000640"
     CDS             20412..21008
                     /gene="recR"
                     /locus_tag="VWX69_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU9192026.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21184..22227
                     /locus_tag="VWX69_000641"
     CDS             21184..22227
                     /locus_tag="VWX69_000641"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU9192027.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22311..23684
                     /locus_tag="VWX69_000642"
     CDS             22311..23684
                     /locus_tag="VWX69_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU9192028.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            23671..24282
                     /locus_tag="VWX69_000643"
     CDS             23671..24282
                     /locus_tag="VWX69_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9192029.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24373..25077
                     /locus_tag="VWX69_000644"
     CDS             24373..25077
                     /locus_tag="VWX69_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU9192030.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25296..26669
                     /gene="ftsA"
                     /locus_tag="VWX69_000645"
     CDS             25296..26669
                     /gene="ftsA"
                     /locus_tag="VWX69_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU9192031.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26686..27945
                     /gene="ftsZ"
                     /locus_tag="VWX69_000646"
     CDS             26686..27945
                     /gene="ftsZ"
                     /locus_tag="VWX69_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU9192032.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27950..28621
                     /locus_tag="VWX69_000647"
     CDS             27950..28621
                     /locus_tag="VWX69_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU9192033.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28631..29170
                     /locus_tag="VWX69_000648"
     CDS             28631..29170
                     /locus_tag="VWX69_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU9192034.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29170..29433
                     /locus_tag="VWX69_000649"
     CDS             29170..29433
                     /locus_tag="VWX69_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU9192035.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29430..30215
                     /locus_tag="VWX69_000650"
     CDS             29430..30215
                     /locus_tag="VWX69_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU9192036.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30224..31012
                     /gene="divIVA"
                     /locus_tag="VWX69_000651"
     CDS             30224..31012
                     /gene="divIVA"
                     /locus_tag="VWX69_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU9192037.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31360..34152
                     /locus_tag="VWX69_000652"
     CDS             31360..34152
                     /locus_tag="VWX69_000652"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU9192038.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            34555..34935
                     /locus_tag="VWX69_000653"
     CDS             34555..34935
                     /locus_tag="VWX69_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192039.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            35129..35419
                     /locus_tag="VWX69_000654"
     CDS             35129..35419
                     /locus_tag="VWX69_000654"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192040.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            35470..36162
                     /locus_tag="VWX69_000655"
     CDS             35470..36162
                     /locus_tag="VWX69_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU9192041.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            36215..38626
                     /locus_tag="VWX69_000656"
     CDS             36215..38626
                     /locus_tag="VWX69_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9192042.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAVRASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            38876..39577
                     /locus_tag="VWX69_000657"
     CDS             38876..39577
                     /locus_tag="VWX69_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192043.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANCDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            39579..42287
                     /locus_tag="VWX69_000658"
     CDS             39579..42287
                     /locus_tag="VWX69_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9192044.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGIVVGETQIQFYWTYSLLALVLSWLASVLPVYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSETPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(42383..42874)
                     /gene="tpx"
                     /locus_tag="VWX69_000659"
     CDS             complement(42383..42874)
                     /gene="tpx"
                     /locus_tag="VWX69_000659"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU9192045.1"
                     /translation="MVTFLGNPVSFTGKQLQGGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(42997..43926)
                     /gene="psaA"
                     /locus_tag="VWX69_000660"
     CDS             complement(42997..43926)
                     /gene="psaA"
                     /locus_tag="VWX69_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU9192046.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(43958..44806)
                     /locus_tag="VWX69_000661"
     CDS             complement(43958..44806)
                     /locus_tag="VWX69_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9192047.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(44803..45525)
                     /locus_tag="VWX69_000662"
     CDS             complement(44803..45525)
                     /locus_tag="VWX69_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9192048.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        13836 a         8130 c        10023 g        13546 t
ORIGIN      
        1 gtatttctct cttaaaagtt tttggtgaaa cgagatgtag aaaggagatt tagccaaaga
       61 gtctattagt gctagaataa tagattagaa ttattttaga aaaacgaagt gagcagctta
      121 taaattcaag tccccaaata gattcatact agtatctttt gcaaaaaata aagggcgact
      181 tccttcatga atatcaattt catctataag gaaggtagct aattgaacta acttatttat
      241 tctgtttgtc gctagaaaaa tcagacctcc ttgtgaagat tgaggagata cttaatgaaa
      301 atcaaagaag aaactagcaa gctagtagca gattgcccaa aacaccgctt tgaggttgta
      361 gataagactg acgtatataa tccaaggtga agcgactgtg gtttgaagag attttcaaag
      421 agtataggct agagagtagt gtttttatgt ccttctagta gaaaatgcta gacagaagaa
      481 tggggaactt ggataggaga aatagattga gaaaggaggt tagaagagat gattattaca
      541 aaaattagcc gtttaggaac ttatgtggga gtaaatccac attttgcaac attaatagat
      601 tttctagaaa aagcaggact agaaaattta acagaaggtt cgattgctat cgatggtaat
      661 cgattgtttg ggaattgctt tacttatcta gcagatggtc aagcaggggc tttctttgaa
      721 acacaccaaa aatatttgga tattcattta gttttggaaa acgaagaagc catggctgtt
      781 acatcgccgg aaaatgtaag cgttacccaa gaatatgatg aagagaaaga tattgaatta
      841 tacacaggga aagtggaaca gttggttcag ttgagagctg gcgaatgcct catcactttt
      901 ccagaagatt tacatcaacc caaggttcgt ataaatgatg aacctgtgaa aaaagttgtc
      961 tttaaagttg cgatttctta atgtagaaag agaagaacga tgaaaaaaat gagaaagttt
     1021 ttatgtctag ctggaattgc gctagcggct gttgccttgg tagcttgttc aggaaaaaaa
     1081 gaagctacaa ctagtactga accaccaaca gaattatctg gtgagattac aatgtggcac
     1141 tcctttactc aaggaccccg tttagaaagt attcaaaaat cagcagatgc tttcatgcaa
     1201 aagcatccaa aaacgaaaat caagattgaa acattttctt ggaatgactt ctatactaaa
     1261 tggactacag gtttagcaaa tggaaatgtg ccagatatca gtacagctct tcctaaccaa
     1321 gtaatggaaa tggtcaactc agatgctttg gttccgctaa atgattctat caagcgtatt
     1381 ggacaagata aatttaacga aactgcctta aatgaagcaa aaatcggaga tgattactac
     1441 tctgttcctc tttattcaca tgcacaagtc atgtgggtta gaacagattt gttaaaagaa
     1501 cataatattg aggttcctaa aacttgggat caactctatg aagcttctaa aaaattgaaa
     1561 gaagctggag tttatggctt gtctgttccg tttggaacaa atgacttaat ggcaacacgt
     1621 ttcttgaact tctacgtacg tagtggtgga ggaagcctct taacaaaaga tcttaaagca
     1681 gacttgacaa gccaacttgc tcaagatggt attaaatact gggttaaatt gtataaagaa
     1741 atctcacctc aagattcttt gaactttaat gtccttcaac aagctacctt gttctatcaa
     1801 ggaaaaacag catttgactt taactctggc ttccatatcg gaggaattaa tgccaacagt
     1861 cctcaattga ttgattcgat tgatgcttat cctattccaa aaatcaaaga gtctgataaa
     1921 gaccaaggaa ttgaaacctc aaacattcca atggttgttt ggaaaaattc aaaacatcca
     1981 gaagttgcta aagcattctt agaagcactt tataatgaag aagactacgt taaattcctt
     2041 gattcaactc cagtaggtat gttgccaact attaagggga ttagcgattc tgcagcctat
     2101 aaagaaaatg aaactcgtaa gaaatttaaa catgctgaag aagtaattac tgaagctgtt
     2161 aaaaaaggta ctgctattgg ttatgaaaat ggaccaagtg tacaagctgg tatgttgact
     2221 aaccaacaca ttattgaaca aatgttccaa gatatcatta caaatggaac agatcctatg
     2281 aaagcagcaa aagaagcaga aaaacaatta aacgatttat ttgaggctgt tcagtagatg
     2341 taaaagacta gaaaataggt gggctagtga gctgaaaagc tctagcccaa tcttgtaaaa
     2401 gaagggagaa ggagaatggt taaagaacgt aatttaactc gctggatatt tgttttgcca
     2461 gctatgatta tcgtaggatt actctttgtt tatccgtttt tctcgagtat tttttatagc
     2521 tttaccaata agcatttgat tatgcctaat tataaatttg ttggtttggc taactataaa
     2581 gctgtgctat cagatcccaa cttctttaat gcgttcttta attcaattaa gtggaccgtt
     2641 ttctcattag ttggtcaagt tttagtaggg tttgtattgg ctttagctct tcacagagta
     2701 cgccacttca agaaattata taggacctta ttgattgttc cttgggcatt tcctaccatc
     2761 gttattgcct tctcttggca gtggattata aacggggttt atggctactt acctaatcta
     2821 atcgtaaaat taggtttaat ggaacataca cctgcatttt tgacagatag tacatgggca
     2881 ttcctatgtt tggtgtttat caacatttgg tttggagcac caatgattat ggttaatgtg
     2941 ctttcagctt tgcaaacagt accagaagaa caatttgagg ctgctaagat agatggtgct
     3001 tcaagttggc aggtgttcaa gtttatcgtc tttccacata ttaaagtggt tgtaggactt
     3061 ctagttgttt tgagaactgt atggatcttt aataactttg acattatcta cctcattact
     3121 ggtggtggac cagccaatgc tacaacgacg cttccaattt ttgcttacaa cctgggttgg
     3181 ggaactaaat tgttgggtcg tgcttcagca gttacagtat tgctctttat cttcttggtg
     3241 gcgatttgct ttatctactt tgctatcatc agtaagtggg aaaaggaggg tagaaaataa
     3301 tgaagaagaa atccagtatt tatttagata ttctctcaca tgtactttta gttggtgcga
     3361 ccatcgttgc aattttccca ttggtatgga ttatcatatc ttctgtcaaa gggaaagggg
     3421 aattaactca gtatccaaca cgattttggc ctgaacagtt tacattagat tatttcactc
     3481 atgttatcaa cgatttgcac ttcattgata acattcgaaa cagtttaatc attgccttgg
     3541 ctacaaccct cattgcgatt attatttctg ctatggcagc ctatggtatt gttcgattct
     3601 ttcctaaatt gggagcaatc atgtcgagac tactcgtcat tacctacatt ttcccaccaa
     3661 ttttgttagc aattccctat tcaattgcca ttgctaaagt tgggttaaca aatagtttat
     3721 ttggcttgat gatggtttat ctatctttta gtgttccata tgcagtttgg ctcttagttg
     3781 gatttttcca aacagttcca attggaattg aagaagcggc tagaattgat ggtgcaaata
     3841 aatttgttac gttttataaa gttgtgctac cgattgtagc accaggtatt gtagcaacag
     3901 ctatttatac atttatcaat gcttggaatg aattcctgta tgccttgatt ttgattaaca
     3961 atacaggaaa gatgacagta gcagtagccc ttcgttcact taatggttca gaaatactag
     4021 actggggaga tatgatggca gcgtctgtta ttgtagttct tccatcaatt attttcttct
     4081 ctatcatcca aaataagatt gcaagtggat tatcagaagg atctgtgaag tagacgaaag
     4141 aaggaaaaaa atgaataaaa gaggtcttta ttcaaaacta ggaatttctg ttgtaggcat
     4201 tagtctttta atgggagtcc ccactttgat tcatgcgaat gaattaaact atggtcaact
     4261 gtccatatct cctatttttc aaggaggctc atatcaactg aacaataaga gtatagatat
     4321 cagccctttg ttattagata aattgtctgg agagagtcag acagtagtaa tgaaatttaa
     4381 agcagatgaa ccaaactctc ttcaagcttt gtttggccta tctaatagta aagcaggctt
     4441 taaaaataat tacttttcaa ttttcatgag agattctggt gagataggtg tagaaataag
     4501 agacgcccaa aagggaataa attatttatt ttccagacca gcttcattat ggggaaaaca
     4561 taaaggacag gcagttgaaa atacactagt atttgtatct gattctaaag ataaaacata
     4621 cacaatgtat gttaatggaa tagaagtgtt ctctgaaaca gttgatacat ttttgccaat
     4681 ttcaaatata aatggtatag ataaggcaac actaggagct gttaatcgtg aaggtaagga
     4741 acattacctc gcaaaaggaa gtattggtga aatcagtcta tttaacaaag caattagtga
     4801 tcaggaagtt tcaactattc ccttatcaaa tccatttcag ttaattttcc aatcaggaga
     4861 ttctactcaa gctaactatt ttagaatacc gacactatat acattaagta gtggaagagt
     4921 tctatcaagt attgatgcac gttatggtgg gactcatgat tctaaaagta agattaatat
     4981 tgccacttct tatagtgatg ataatgggaa aacgtggagt gagccaattt ttgctatgaa
     5041 gtttaatgac tatgaggagc agttagttta ctggccacga gataataaat taaagaatag
     5101 tcaaattagt ggaagtgctt cattcataga ttcatccatt gttgaagata aaaaatctgg
     5161 gaaaacgata ttactagctg atgttatgcc tgcgggtatt ggaaataata atgcaaataa
     5221 agccgactca ggttttaaag aaataaatgg tcattattat ttaaaactaa agaagaatgg
     5281 agataacgat ttccgttata cagttagaga aaatggtgtc gtttatgatg aaacaactaa
     5341 taaacctaca aattatacta taaatgataa gtatgaagtt ttggagggag gaaagtcttt
     5401 aacagtcgaa caatattcgg ttgattttga tagtggctct ttaagagaaa aacataatgg
     5461 aaaacaggtc cctatgaatg ttttctacaa agattcgtta tttaaagtga ctcctactaa
     5521 ttatatagca atgacaacta gtcagaatag aggagagagt tgggaacaat ttaagttgtt
     5581 gcctccgttc ttaggagaaa aacataatgg aacttactta tgtcccggac aaggtttagc
     5641 attaaaatca agtaacagat tgatttttgc aacatatact agtggagaac taacctatct
     5701 catttctgat gatagtggtc aaacatggaa gaaatcctca gcttcaattc cgtttaaaaa
     5761 tgcaacagca gaagcacaaa tggttgaact gagagatggt gtgattagaa cattctttag
     5821 aaccactaca ggtaagatag cttatatgac tagtagagat tctggagaaa catggtcgga
     5881 agtttcgtat attgatggaa tccaacaaac ttcatatggc acacaagtat ctgcaattaa
     5941 atactctcaa ttaattgatg gaaaagaagc agtcattttg agtacaccaa attctagaag
     6001 tggccgtaag ggaggtcaat tagttgtcgg tttagtcaat aaagaagatg atagtattga
     6061 ttggaaatac cactatgata ttgatttgcc ttcgtatggt tatgcctatt ctgcgattac
     6121 agaattgcca aatcatcaca taggtgtact gtttgaaaaa tatgattcgt ggtcgagaaa
     6181 tgaattgcat ttaagcaatg tagttcagta tatagatttg gaaattaatg atttaacaaa
     6241 ataaaggaga aaaacatggt taaatacggt gttgttggag cagggtattt tggagctgaa
     6301 ttggctcgct acatgcaaaa gaatgatgga gcagagatta ctcttctcta tgatccagat
     6361 aatgcagagg cgattgcaga agaattggga gcaaaagtag caagttcctt agatgagttg
     6421 gtttctagcg atgaagtaga ttgtgttatc gtcgcaactc caaataatct tcataaggaa
     6481 ccggttatta aggctgcaca gcatggtaaa aatgttttct gtgaaaaacc aattgcgctt
     6541 tcttatcaag attgtcgcga gatggtagat gcgtgtaaag aaaacaatgt aacctttatg
     6601 gcaggacata ttatgaattt ctttaatggt gttcatcatg caaaagaact cattaatcaa
     6661 ggagttatcg gagacgttct atattgtcat acagctcgta atggttggga agaacaacaa
     6721 ccgtcagtat catggaaaaa aattcgtgaa aaatcaggtg gtcacttgta tcaccacatc
     6781 catgaattgg attgcgttca attccttatg gggggcatgc ctgaaactgt aaccatgaca
     6841 ggtggaaatg tggcccatga aggtgaacat ttcggtgatg aagatgatat gatttttgtc
     6901 aatatggaat tttctaataa gcgttttgct ttgttagaat ggggttcagc ttatcgttgg
     6961 ggtgaacatt atgtcttaat ccaaggaagc aaaggtgcca tccgcttaga cttattcaac
     7021 tgtaaaggaa ctcttaagct agatgggcaa gaaagctatt tcttgattca cgaatcgcaa
     7081 gaagaagatg atgatcggac tcgtatctat catagtacag agatggatgg agcaattgct
     7141 tatggtaaac caggtaaacg tactccatta tggctatcat ctgtcattga taaagaaatg
     7201 cgctatctgc atgagattat ggaaggagct ccagtatcag aagaatttgc aaaacttttg
     7261 acaggtgaag ctgccctaga agcaattgct actgcagatg cttgtaccca gtctatgttt
     7321 gaagatcgca aagtaaaatt gtcagaaatt gtaaaataaa ttttggtatt ctcctattta
     7381 taggtcgact tgctcctctg aaagtacttt tagaggagct gtttgacttt gctagttttt
     7441 gaaactgaaa tctattatac tacaaactat tgaaagcgtt ttaattttaa ggtataataa
     7501 tctcatagaa ataaagaaaa ggaggaaaga ggatgccaca gattagcaaa gaagccttga
     7561 ttgagcaaat caaagatgga atcatcgttt cttgtcaggc tcttcctcat gaaccgcttt
     7621 atacagaagc gggaggggtg attcccttgc tggtcaaagc ggctgagcaa ggtggagcag
     7681 tcggtatccg agcaaacagt gttcgcgata tcaaggaaat taaggaggtc actaaacttc
     7741 caatcattgg gattatcaaa cgtgattatc cacctcagga acccttcatc acggctacta
     7801 tgaaagaagt tgatgaattg gcagaactgg acatcgaggt gattgctctg gattgtacca
     7861 agcgtgaacg ctacgatggt ttggaaattc aagagttcat tcgtcaggtt aaggagaaat
     7921 atcctaatca gcttttgatg gctgatacta gtatcttcga agaagggcta gcagctgtag
     7981 aagcaggaat tgactttgtc ggaacaacct tatcaggcta cacatcctac agtccaaaag
     8041 tagacggtcc agattttgaa ttgattaaga aactctgtga tgccggtgta gatgtcattg
     8101 cagaaggaaa aattcataca ccagaacaag ccaaacaaat ccttgaatat ggagtgcgag
     8161 gcatcgttgt tggtggcgcc attactagac caaaagagat tacagaacgc ttcgttgcta
     8221 gtcttaaata agatgtgagg gggagtttta tgtttaaagt tttacaaaaa gttggaaaag
     8281 cttttatgtt acctatagct atacttcctg cagcaggtct acttttgggg attggtggtg
     8341 cactttcaaa cccaaccacg atagcaactt atccaatact agacaatagt atttttcaat
     8401 caatattcca agtaatgagc tctgcaggag aggttgtatt cagtaatttg tcactacttc
     8461 tctgtgtggg attatgtatt ggcttagcga aacgagataa aggaaccgct gcgttagcag
     8521 gagtaactgg ttacttagtt atgactgcaa cgatcaaagc tttggtaaaa ctttttatgg
     8581 cagaaggatc tgcaattgat actggagtta ttggagcatt agctgtcgga atagttgccg
     8641 tatatttgca caaccgatat aacaatattc aattaccttc cgctttagga ttctttggag
     8701 gttcacgctt cgttcctatt gttacatcgt tctcttctat cttgattggc tttgtcttct
     8761 ttgttatttg gccacctttc caacaacttc ttgtttctac aggtggatat atttctcagg
     8821 cgggtccaat tggaactttt ctatatggat ttttaatgag actttctgga gcagtaggct
     8881 tacatcatat aatttaccct atgttttggt atactgaact tggtggtgtt gaaactattg
     8941 caggacaaac agtggttgga gctcaaaaaa tattttttgc tcaattagcc gatccggccc
     9001 attctggatt atttacagaa ggaacaaggt tttttgcagg tcgtttctca acaatgatgt
     9061 tcggtttacc ggctgcctgt ttagcgatgt accatagtgt tcctaaaaat cgtcgtaaaa
     9121 aatacgcggg tttgtttttt ggagttgctt taacatcttt tattaccggt attacagaac
     9181 caattgaatt tatgtttcta ttcgtcagtc cggttctata tgttgttcac gcattccttg
     9241 atggtgttag cttctttatt gcagacgtct taaatatttc aataggaaac acattttcag
     9301 gaggtgtaat cgatttcact ttatttggaa ttttgcaggg gaacgctaag acgaattggg
     9361 ttcttcagat tccaattgga cttatttgga gtgttttgta ttatattatt tttagatggt
     9421 tcattactca attcaatgtt ctaacgccag gacgaggaga agaagtagat tctaaagaaa
     9481 tttctgaatc cgcagattca acttcaaata ctgcagatta tttaaaacag gatagcctac
     9541 aaattatcag agccttgggt ggatcaaata atatagaaga tgtagatgct tgtgtgacac
     9601 gtttacgtgt agctgtaaaa gaagttaatc aagttgataa agcactttta aaacaaattg
     9661 gtgcagttga tgtcttagaa gtgaagggtg gcattcaagc aatctatgga gcaaaagcaa
     9721 tcttatataa aaatagtatt aatgaaattt taggtgtaga tgattaagta cttactgact
     9781 taataaaaaa cagaggagag tgatggatga gtaggatgaa atgaaatcgc atacaagaaa
     9841 taaagaactc attatccaag ttggatacgc ttattacata ggagaataca aatgaaattt
     9901 agaaaattag cttgtacagt acttgcgggt gctgcggttc ttggtcttgc tgcttgtggc
     9961 aattctggcg gaagtaaaga tgctgccaaa tcaggtggtg acggtgccaa aacagaaatc
    10021 acttggtggg cattcccagt atttacccaa gaaaaaactg gtgacggtgt tggaacttat
    10081 gaaaaatcaa tcatcgaagc gtttgaaaaa gcaaacccag atataaaagt gaaattggaa
    10141 accatcgact tcaagtcagg tcctgaaaaa atcacaacag ccatcgaagc aggaacagct
    10201 ccagacgtac tctttgatgc accaggacgt atcatccaat acggtaaaaa cggtaaattg
    10261 gctgagttga atgacctctt cacagatgaa tttgttaaag atgtcaacaa tgaaaacatc
    10321 gtacaagcaa gtaaagctgg agacaaggct tatatgtatc cgattagttc tgccccattc
    10381 tacatggcaa tgaacaagaa aatgttagaa gatgctggag tagcaaacct tgtaaaagaa
    10441 ggttggacaa ctgatgattt tgaaaaagta ttgaaagcac ttaaagacaa gggttacaca
    10501 ccaggttcat tgttcagttc tggtcaaggg ggagaccaag gaacacgtgc ctttatctct
    10561 aacctttata gcggttctgt aacagatgaa aaagttagca aatatacaac tgatgatcct
    10621 aaattcgtca aaggtcttga aaaagcaact agctggatta aagacaattt gatcaataat
    10681 ggttcacaat ttgacggtgg ggcagatatc caaaactttg ccaatggtca aacatcttac
    10741 acaatccttt gggcaccagc tcaaaatggt atccaagcta aacttttaga agcaagtaag
    10801 gtagaagtgg tagaagtacc attcccatca gacgaaggta agccagctct tgaatacctt
    10861 gtaaacgggt ttgcagtatt caacaataaa gacgacaaga aagtcgctgc atctaagaaa
    10921 ttcatccagt ttatcgcaga tgacaaggag tggggaccta aagacgtagt tcgtacaggt
    10981 gctttcccag tccgtacttc atttggaaaa ctttatgaag acaaacgcat ggaaacaatc
    11041 agcggctgga ctcaatacta ctcaccatac tacaacacta ttgatggatt tgctgaaatg
    11101 agaacacttt ggttcccaat gttgcaatct gtatcaaatg gtgacgaaaa accagcagat
    11161 gctttgaaag ccttcactga aaaagcgaac gaaacaatca aaaaagctat gaaacaatag
    11221 tccttagtta ttctataaaa agtagttttt taaagaacct aagagtgtat accccctttt
    11281 ccctctacac agatagtgta agaaaagggg gcttttgttt aaaatgtaag aaactgtcac
    11341 gaaattaaaa tgaagttctt acataagcga atcataaaaa atttcatttt gattttaaaa
    11401 cagttcaaga aagtcaaaaa attattctat ttgaaagaga ggtgccgact gtgaaagtca
    11461 ataaaatccg tatgcgggaa acagtgattt cctacgcttt cctagcacca gtattattct
    11521 tctttgtcat ctttgtgttg gctccgatgg tgatgggctt cattacaagt ttctttaact
    11581 actcaatgac taaatttgag tttgtaggct tggataacta tatccgtatg tttaaagatc
    11641 ctgtctttac aaaatctctg attaacacag ttattttggt tattggatct gtaccagttg
    11701 ttgttctatt ctcactcttt gtagcatctc agacctatca tcaaaatgtc attgccagat
    11761 ccttctaccg tttcgtcttc ttccttcctg ttgtaacggg tagtgttgcc gtgacagttg
    11821 tttggaaatg gatttatgac ccactatcag ggattctaaa ctttgtcctt aagtccagcc
    11881 acatcatcag ccaaaacatt tcttggttgg gagataaaaa ctgggcattg atggcgatta
    11941 tgattattct cttgaccact tcagttggtc agcccatcat cctttatatc gctgccatgg
    12001 ggaatattga caattcactg gttgaagcgg cgcgtgttga tggtgcaact gagtttcaag
    12061 ttttttggaa gattaaatgg ccaagccttc ttccaacaac tctttatatt gcaatcatca
    12121 caacaattaa ctcattccag tgttttgcct tgattcagct tttgacatct ggtggtccaa
    12181 actactcaac aagtaccttg atgtactacc tttacgaaaa agccttccaa ttgacagaat
    12241 acggctatgc caacacaatt ggtgtcttct tggcaatcat gattgctatc gtaagctttg
    12301 ttcaatttaa agtacttgga aacgacgtag aatactaaag aaaggagaca gctatgcaat
    12361 ctacagaaaa aaaaccatta acagccttta ctgttatttc aacaatcatt ttgctcttgt
    12421 tgactgtgct gttcatcttt ccattctact ggattttgac aggggcattc aaatcacaac
    12481 ctgatacaat tgttattcct cctcagtggt tccctaaaat gccaaccatg gaaaacttcc
    12541 aacaactcat ggtgcagaac cctgccttgc aatggatgtg gaactcagta tttatctcat
    12601 tggtaaccat gttcttagtc tgtgcaacct catctctagc aggttatgta ttggctaaaa
    12661 aacgtttcta tggtcaacgc attctatttg ctatctttat cgctgctatg gcgcttccaa
    12721 aacaagttgt ccttgtacca ttggtacgta tcgtcaactt catgggaatc cacgatactc
    12781 tctgggcagt tatcttgcct ttgattggat ggccattcgg tgtcttcctc atgaaacagt
    12841 tcagtgaaaa tatccctaca gagttgcttg aatcagctaa aatcgacggt tgtggtgaga
    12901 ttcgtacctt ctggagtgta gccttcccga ttgtgaaacc agggtttgca gcccttgcaa
    12961 tctttacctt catcaatact tggaatgact acttcatgca attggtaatg ttgacttcac
    13021 gtaacaattt gaccatctca cttggggttg cgaccatgca ggctgaaatg gcaaccaact
    13081 atggtttgat tatggcagga gctgcccttg ctgctgttcc aatcgtcaca gtcttcctag
    13141 tcttccaaaa atccttcaca cagggtatta ctatgggagc ggtcaaagga taatactctg
    13201 agaaaatctc ttcaaactac gtcagcgtca ccttgccata cttaagtatt gcctgcggtt
    13261 agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct atcaagatac
    13321 agaagtatat tttatagatt tagagaatat agaggttata agtgtctaca aaatggaggg
    13381 tatgcagtta ctttatgaag ttttgtcaga cacttataaa cttaagaatg gttttagtta
    13441 actatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat caccttttac
    13501 aaagggattc atcccaattt agacaaggct atcgactatc tctaccaaca tcgtaaagat
    13561 tcattcgaat taggaaagta tgagattgat ggagataaag tctttctagt tgttcaggaa
    13621 aatgtcctca atcaagttga gaataatcga tttgaacacc ataagaacta tgcagatttg
    13681 catttgctga tagaagggca tgaatattcg agctacggtt cacgtatcaa agacgaggca
    13741 gtagcattcg acgaagcgag tgacattggc tttgttcatt gtcatgaaca ctacccactc
    13801 ttgttgggtt atcacaattt tgcgattttc ttcccaggtg agccacatca gccaaatggt
    13861 tatgcaggca tggaagaaaa ggttcgaaaa tatctcttta aaattttgat tgattaaaaa
    13921 taggatgaat tgtttttttg taaagctttg ataatactct accatgaaat tgatctttgt
    13981 gaggtagaga aatgagaata aaatatttaa aaattggtat cttctaagta tgctgcaaga
    14041 gctagtttct tagatggaca ggggattaca gttgatgaga tggcttggat aattaggggc
    14101 attgtgactg cattgattgg tagatacata aaattaggta cttatgcagt taagtatggt
    14161 attagtatgg cgcgctcgat cttaagtagg gcagctgcaa ctgcggcagc aagagtagga
    14221 ttattgacta agatttttgg atggatttta cgaatagctg tgctcgcagc tgatgtatat
    14281 ggtaattttg ccaacaatat tgctgtagct tgggatgcac atgataaaat ccctaacaat
    14341 ggtcgtataa acttttaaaa tgcgagaatg aaagcacttt gtattttttt attgtatatg
    14401 ttagcttgga cagtgcttgc aatgataatc cgtggagggc tagatggatt tgatgaacac
    14461 acttggcgta ctattttaat tgcttcgctg tccgggatat atatagatta tatgtccata
    14521 gataaaagta gaaaaaagtc caaaagaaaa aagaaaaaat agatttgttc atggtaggga
    14581 cttatgaaag ctttactgac aaaaaagaaa acagtttaca aagaaaaatg atggaggagc
    14641 aaacatggca caaaaaggag taagccttat caaggcagca tttgatacag ataactttct
    14701 catgcgtttt agtgagaaag tcttggacat cgtgacagcc aatcttcttt ttgtcgtctc
    14761 ttgtttgccc atcgtgacga ttggagtggc taaaatcagc ctctacgaga ccatgttcga
    14821 agttaagaag agcagacggg tgcctgtttt taaaatctat ctaagatctt tcaagcaaaa
    14881 tctgaaacta ggtcttcagc tgggtttaat ggagttagga attgtgtttc ttaccctttc
    14941 agatctctat cttttctggg gtcaaacagc tctgcccttc caattgctga aagccatttg
    15001 tctaggcatt ctgattttcc ttacgattgt gatgttggct agctatccaa tcgcggcacg
    15061 ttatgattta acttggaaag aagtgttaca aaaagggctt atcttggcta gttttaactt
    15121 tccttggttc ttcctcatgt tagccattct tgtcctcatt gtgatggttc tttatctgtc
    15181 cgccttcagt ctactcttag gtggctcagt cttcctactt tttgggtttg gactattggt
    15241 ctttatccag actggattga tggagaaaat tttcgcaaaa taccaatagg agccttattt
    15301 ctgaaactac tttcaaaggc tccaaacgct attctataag cgagaaacta aaatctaagt
    15361 gtctataaga tattgaaagc cttttcggta aagtgtatac taaagaagta aagaaaaatc
    15421 tgctttagca gaaaataaaa ataataggag aaaatctatg tcagatttga aaaaatacga
    15481 aggtgtcatt ccagccttct acgcatgtta tgatgagcaa ggagaagtaa gtccagagcg
    15541 tacgcgtgcc ttggttcaat acttcattga taaaggtgtt caaggtcttt atgtcaatgg
    15601 ttcttctggt gaatgtatct accaaagcgt tgaagatcgc aagttgattt tggaagaagt
    15661 catggcggta gccaaaggta aattgaccat tattgcccat gttgcttgca ataatactaa
    15721 agatagtatg gaacttgctc gccatgctga aagcttggga gtagatgcta ttgcaacgat
    15781 tccaccaatt tacttccgct tgccagaata ctcagttgcc aaatactgga acgatattag
    15841 ttctgcagct ccaaacacag actacgtgat ttacaacatt cctcaattgg caggggttgc
    15901 tttgacttca agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg gtgttaagaa
    15961 ctcttcaatg ccagttcaag atatccaaac ctttgtcagc cttggcgggg aagaccatat
    16021 tgtctttaac ggtccagatg aacagttcct aggtggccgc ctcatgggtg ctaaggctgg
    16081 tatcggtggt acttatggtg ctatgccaga actcttcttg aaactcaatc agttgattgc
    16141 ggataaagat ttagaaacag cgcgtgaatt gcagtatgct atcaacgcaa tcattggtaa
    16201 actcactgct gcacatggaa atatgtacgg tgtcatcaaa gaagttttga agatcaatga
    16261 aggcttgaat attggttctg ttcgttcacc attgacacca gtgactgaag acgatcgtcc
    16321 agttgtagaa gcggctgcag ccttgattcg tgaaaccaag gagcgcttcc tctaatctaa
    16381 aaggaggtat ttatgacata ctacgttgca attgatatcg gtggaactaa catcaagtat
    16441 ggtttggttg atcaagaggg gcaacttctt gaatcacatg aaatgccaac agaggcgcat
    16501 aagggtggac ctcatatctt acaaaagacc aaagatatcg tagctagtta tttagaaaaa
    16561 ggcccagtag caggtgttgc catatcttct gctgggatgg tggatccgga taagggtgag
    16621 attttctatg ctgggccgca aatccctaac tacgcaggca cccagttcaa aaaggaaatc
    16681 gaagaaagct ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc aggtcttgct
    16741 gaggcagtat ctggttcagg caagggagca agtgtgacac tttgcttgac cattggaacc
    16801 ggtatcggtg gttgcttgat tatggatagg aaagtcttcc atggttttag taattcagcc
    16861 tgtgaagtcg ggtatatgca tatgcaggat ggagcttttc aggatctcgc ttctacaaca
    16921 gctttagtga aatatgtagc tgaagcccat ggagaagatg ttgatcagtg gaatggccga
    16981 cgtatcttta aggaagctac tgaaggaaac aaaatctgca tggaaggtat tgaccgtatg
    17041 gttgactatc taggaaaagg tctggcaaat atttgctacg ttgccaatcc agaagtggtc
    17101 attcttggtg gtggtatcat ggggcaagag gctatcctca aacctaagat ccgcacagcc
    17161 ttgaaagagg ctttggtacc aagtttagca gaaaaaacac gattagaatt tgcccatcac
    17221 caaaatacag cagggatgtt gggtgcatat tatcatttta agacaaaaca atcctagttt
    17281 ggctcagcca aactaggatt ttcttacacg tttttgtcta cgatagccgt tgagtttttt
    17341 attttcccag tagctattaa agattttttc cttgctttcg cgattgattt ccaaaaagta
    17401 ggcataaatc aaatcgataa agaagagcat aggaagttga gcggatattc gttggatata
    17461 ggagggttgg ctgtgggtgg ctacaagaac agtctctgta taggtctggc tatttttatt
    17521 gggaacactt gtaaagagta cagtctttgc ccccatctcc ttggcatcta atagactatc
    17581 taaaatagaa ggagttgagc ctgaaagtga gaagcccagt actagacaat tttcatccat
    17641 gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga ccacacctaa
    17701 tcgcataaaa cgtaatttca tttcacgggc gacgaggcca gaactccctg ttccaaagaa
    17761 gtagatacgc tcagcatctt cgattagctg ggcaattcgt tctagttgga tttcgtcaat
    17821 caagtcttgt gtttgttccc tcatattgct ataacttctg aggactcgtt tggtcagtgg
    17881 actgtgcttg gaaacttggt tggcttgatt ttctgcctga tgttggtatt ggaaaataaa
    17941 ttctcggtag ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag cttgagaaat
    18001 atgtaatttt tgggtgactt gttgagaaga taaatcatct gtaatcgttt cagcttgcaa
    18061 aaaatagcga gcgatttctt gctctaggtc tgtcatttct tcaaaatgtg aatcaatgat
    18121 agttgcgata tctggtttgt ccatagggaa agctccttta catgagtcat actggaagac
    18181 tagatcaggg aatagtcaca cttcattata acacataata taaggataga taaataaaaa
    18241 cgcatctctg ttttaaaaac gaaaaaatcg aaaaagcttc tctcttttcc ataattttct
    18301 actcaaattg tggtacaatt aagagtaaga ttttaagtta gaaatgagac tgatttgtat
    18361 gagaaaattt aacagccatt cgattccgat tcggcttaat ttattgtttt caatcgtcat
    18421 tttactcttt atgaccatta ttggtcgttt gttgtatatg caggttttga acaaggattt
    18481 ttacgaaaaa aagctagcct cagctagtca gaccaagatt acaagcagtt cagcccgtgg
    18541 ggaaatttat gatgctagtg gaaaaccttt ggtagaaaat acgttaaagc aggttgtttc
    18601 ctttacgcgt agcaataaaa tgacggctac agacttaaaa gaaacagcta aaaagttact
    18661 gacttatgtg agcatcagtt ctccaaattt gacagaacgc cagctggcgg attactattt
    18721 ggctgatcct gaaatctata aaaaaatagt ggaagctctc ccaagcgaga aacgcttgga
    18781 ttcagatggc aatcgtctat ccgaatcaga actgtataac aatgcggtcg atagtgtaca
    18841 aacgagtcaa ctaaactata cagaggatga aaagaaagaa atctatcttt ttagtcagtt
    18901 aaatgctgtt ggaaactttg cgacaggaac tattgctaca gatcctctaa atgattctca
    18961 ggtggctgtt attgcctcta tttcaaagga gatgcctggc attagtattt ctacttcttg
    19021 ggatagaaag gttttggaaa cttccctttc ttctatagtt gggagtgtat ccagtgaaaa
    19081 agctggtctc ccagcggaag aagcagaagc ctatcttaaa aaaggctatt ctctaaatga
    19141 tcgtgtagga acctcctatt tggaaaagca atatgaagag accttacaag gaaaacgctc
    19201 ggtaaaagaa atccatctgg ataaatatgg caatatggaa agcgtggata caattgagga
    19261 aggtagtaag ggaaacaata tcaaactgac cattgatttg gctttccaag atagcgtgga
    19321 tgctttactg aaaagttatt tcaattctga gctagaaaat ggtggagcca agtattctga
    19381 aggtgtctat gcagtcgccc ttaacccaaa aacaggtgcg gttttgtcta tgtcagggat
    19441 taaacatgac ttgaaaacgg gagagttgac gcctgattcc ttgggaacgg taaccaatgt
    19501 ctttgttcca ggttcggttg tcaaggcggc gaccatcagc tcaggttggg aaaatggagt
    19561 cttgtcagga aaccagacct tgacagacca gtccattgtc ttccaaggtt cagctcccat
    19621 caattcttgg tatactcagg cttacggttc attccctatc acagcggtcc aagctctgga
    19681 gtattcatca aatacctata tggtccaaac agccttaggt cttatggggc aaacctatca
    19741 acccaatatg tttgtcggca ccagcaatct agagtctgct atggagaaac tgcgttcaac
    19801 ctttggcgaa tatggcttgg gtactgcgac aggaattgac ctaccagatg aatctactgg
    19861 atttgttccc aaagagtata gctttgctaa ttacattact aatgcctttg ggcagtttga
    19921 taactatacg ccgatgcagt tggctcagta tgtagcaact attgcaaata atggtgttcg
    19981 tgtggctcct cgtattgttg aaggcattta tggtaataat gataagggag gactgggtga
    20041 cttgattcag caactgcaac cgacagagat gaataaggtc aatatatccg actccgatat
    20101 gagcatcttg caccaaggtt tttatcaggt tgcccatggt actagtggat tgacaactgg
    20161 acgtgccttt tcaaatggtg ccttggtatc cattagcgga aaaacaggta cagccgaaag
    20221 ctatgtggca gatggtcagc aagcaaccaa taccaatgcg gtggcctatg ccccatctga
    20281 taatccccaa atcgctgtcg cagtggtctt tcctcataat accaatctaa caaatggtgt
    20341 aggaccttcc attgcgcgtg acattatcaa tctgtatcaa aaataccatc caatgaacta
    20401 gaaaggaaat tatgctttat ccaacaccta ttgccaagtt gattgacagt tattctaagt
    20461 taccaggtat cgggattaag acggctacgc gtctggcctt ttatacgatt gggatgtctg
    20521 ctgatgatgt caatgaattt gcaaaaaatc tcctttctgc taagagagaa ttgacatatt
    20581 gttctatttg tggacgtttg acagacgacg atccttgttc tatctgtact gattcgactc
    20641 gtgaccagac aacaatttta gttcttgagg atagtagaga tgtggcagcc atggaaaata
    20701 tccaagaata ccatggactc tatcatgtcc tgcatggcct catttctcct atgaatggta
    20761 tcagtccgga cgatatcaat cttaagagcc ttatgactcg tcttatggat agtgaggttt
    20821 cagaagtgat tgtggcgact aatgctacag cggatggtga agcgacctcc atgtatcttt
    20881 cacgtttgct caagccggct ggtatcaagg ttacgcgtct agcacgaggt ctcgctgtgg
    20941 gagcggacat tgagtatgcg gacgaagtga cactcttacg agcgattgaa aatcggacag
    21001 agttgtaagt gtaggcaaat ttacgaactc cattcattta taaaaaatca aagaggctga
    21061 aaatcgttcc tatcggcctc tttttgtata gtgtgatgag tagaatcagg ttcaagtttt
    21121 aaaaaaccaa gcaaatatga tatactaaag agcgagtatt ctagtagaat taggacaaat
    21181 aatatgaaac aaacgattat tcttttatat ggtggacgga gtgcggaacg cgaagtctct
    21241 gtcctttcag ctgagagtgt catgcgtgcg gtcaattacg accgtttcac agtcaagact
    21301 ttctttatca gtcagtcagg tgactctatc aaaacgcagg aatttagtca tgctccgggg
    21361 caagaagacc gtctcatgac caatgaaacc attgattggg ataagaaagt tgcaccaagt
    21421 gctatctacg aagaaggtgc agtggtcttt ccagtccttc acgggccaat gggagaagat
    21481 ggctctgttc aaggattctt ggaagttttg aaaatgcctt acgttggttg caacattttg
    21541 tcatcaagtc ttgccatgga taaaatcacg actaagcgtg ttctggaatc tgctggtatt
    21601 gcccaagttc cttatgtggc tatcgttgaa ggcgatgatg tgactgctaa aatagctgaa
    21661 gtggaagaaa aattggctta tccagtcttc actaagccgt caaacatggg gtctagtgtc
    21721 ggtatttcta agtctgaaaa ccaagaagaa ctccgtcaag ccttaaaact tgccttccga
    21781 tatgacagcc gtgtcttggt tgagcaagga gtgaatgccc gtgaaattga ggttggcctc
    21841 ttgggtaact acgatgtcaa gagcacgcta cctggagaag ttgtcaagga cgttgccttt
    21901 tatgactacg atgccaagta tattgataac aaggttacta tggatattcc tgccaaaatc
    21961 agtgatgatg tggtggctgt catgcgtcaa aatgcagaaa cagccttccg tgccattggt
    22021 ggccttggtc tatctcgttg cgatttcttc tatacagata agggagagat ttttctcaac
    22081 gagctcaata ccatgccagg tttcacccag tggtctatgt acccactact ttgggaaaat
    22141 atggggatca gctacccaga actaatcgag cgtttggttg accttgccaa ggaaagtttt
    22201 gacaagcgcg aagcgcattt gatataaaat gaaagagagg gtagaagcca gaaccatcac
    22261 tgcaaggtga ctagagttct cggacttcag ccctttttaa aggagtagaa atgaaattaa
    22321 caatccatga aattgcccaa gttgttggag ccaaaaatga tatcagtatc tttgaggaca
    22381 ctcagttaga aaaagctgag tttgatagtc gtttgattgg aactggagat ttatttgtgc
    22441 cacttaaagg tgcgcgtgat ggccatgact ttattgaaac agcctttgaa aatggtgcag
    22501 cagtaacctt gtctgagaaa gaggtctcaa atcatcctta cattttagta gatgatgttt
    22561 tgacagcctt tcaatcccta gcatcctact atcttgaaaa aacgactgtt gatgtctttg
    22621 ctgttacagg ttcaaatggc aagacaacga ctaaggatat gttggcgcat ttactgtcaa
    22681 caagatacaa gacctacaaa acacaaggca attacaataa tgagattggc cttccttaca
    22741 cagttcttca tatgcctgaa ggaacagaaa agttggtttt ggagatggga caggatcact
    22801 tgggagatat tcatctcttg tctgaattgg ctcgtccaaa aacagccatc gtgaccttgg
    22861 ttggagaagc tcatttggcc tttttcaaag atcgttctga gattgctaaa ggaaaaatgc
    22921 aaattgcaga cggaatggct tcaggttcct tgcttttagc gccggctgac cctatcgtag
    22981 aggactattt gccaattgat aaaaaggtgg ttcgttttgg tcaaggagca gagctggaaa
    23041 ttactgactt ggttgagcgt aaggacagtc tgacctttaa ggctaatttc ttggaacaag
    23101 cccttgattt gccagtaact ggcaagtaca atgcgacaaa tgctatgatt gcatcctatg
    23161 ttgccttgca agaaggagtt tcagaggagc aaattcgttt ggcattccaa catcttgaat
    23221 tgacgcgtaa ccgtaccgag tggaagaaag cagccaatgg agcagatatc ctgtcagatg
    23281 tttacaatgc caatccaact gctatgaaac tgattttaga gactttctct gccattccag
    23341 ccaatgaagg tggcaagaaa attgcagtgt tggcggatat gaaggagctt ggtgaccagt
    23401 ctgttcaact tcataatcag atgattttga gcctctcccc agatgtgctt gatatcgtta
    23461 ttttctatgg agaagatatt gctcagttgg ctcaattggc cagtcaaatg tttccaatcg
    23521 gccacgttta ctacttcaag aaaacagaag accaggatca atttgaagac ctagtcaagc
    23581 aggttaagga aagccttgga gcctatgacc aaatcttgct aaaaggttct aactctatga
    23641 atctagccaa attggtagaa agtttagaaa atgaatgcaa gtgattttgc taagtatctt
    23701 caaagaatga ttgctcttac agatactgga ctaaccttta caaaggatcc gtttgaccgt
    23761 gagcgctacg aagacttgcg aagtctgtta tctgaaatgt tgaatcaggt atcagacctt
    23821 gatgcagacg aagtggcaga actcttgaaa ccgacctccg cttatgcgac tcctttaatg
    23881 gacgtccgtg cttggatagt tgaggatgaa aaaatttgtc tggttagggg acaaggagag
    23941 aatgattggg ctttgccagg tggctttggc gaggtcggtt attcaccaac tgaaaatatt
    24001 ctcaaggaaa ttgaagaaga aaccggtttt aaagccaaag ttgaacgact actagctgtt
    24061 tttgatacca atcgtttcca actacagagc aaacaatatg caaagtttgt ttttgaatgt
    24121 aagcttctcg atggacaatt tcaagaaaat caagaaatcg ctgaccttca attttttgca
    24181 attgaccaac tgccgaattt atctgaaaaa cgcattacca aggagcaaat agagcttctt
    24241 tggcaggttt atcaaggtca tagggggcaa tatcttgact aagaagatga ttatcgtatt
    24301 tctaaatcca tttttaacaa ctagcatggt ataataatat gcaggaaaat tttgaattat
    24361 gaggaagact agatgaattt atgggatatt ttctttacga ctcaggcaac cgagccgccc
    24421 aaatttgacc ttttttggta tgttagccta tttacgctct tagccttaac cttttataca
    24481 gcccatcgct atcgtgaaaa taaggtttac caacgatttt tccaaatctt gcagactgtt
    24541 cagttaatcc ttctttatgg ttggtactgg gtcaatcata tgccactgtc agaaagccta
    24601 cccttttacc attgccgtat ggctatgttt gtggtactct tgcttcctgg tcaatccaaa
    24661 tataaacaat actttgcatt attgggaaca tttgggacat tagcagcctt tgtttatcca
    24721 gtgccagatg cttacccttt tccacatatc accattctat cctttatctt tggtcattta
    24781 gcactcttgg ggaactctct agtttatcta ttgagacagt ataatgcgcg attgctggat
    24841 gtgaagggaa tttttctcat gacctttgcc ctaaatgcct tgatttttgt ggtcaatttg
    24901 gtgacaggtg gcgattacgg atttttgaca aaaccgccat tggttgggga tcacggtcta
    24961 gtagctaatt atttacttgt ttcaattgtg ctggtagcta ctatcagttt gactaagaaa
    25021 atcttagaat tctttttagc tcaagaagca gaaaaaatga ttgcaaagga agcttaacac
    25081 agagctttct tttttgctct tagagagttt ttacaagcag cttataaaat aagaatttct
    25141 gaatagacaa actcaaaaaa tggctgggaa atttaggaaa aaagcaagca cgattaaatt
    25201 ttttgtgtta taatattttg tgaatagcta tgcctatgtt tagctatgga ataatacgaa
    25261 gtgcgaaact tggaagatag agaggaagcg atgtaatggc tagagaaggc ttttttacag
    25321 gtctagatat tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga aatggtgaat
    25381 taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga attattgttg
    25441 atattgatgc agcagcaact gctatcaagt cagccatttc ccaagcggaa gaaaaggcag
    25501 gcatttcgat taaatcagtg aatgtcggct tgcctggtaa tcttttgcag gtagaaccaa
    25561 ctcaggggat gattccagta acatctgata ctaaggaaat tacggatcaa gatgttgaaa
    25621 atgttgtcaa atcagctttg acaaagagta tgacacctga ccgtgaagtc attaccttta
    25681 ttcctgaaga atttattgtg gatggtttcc aagggattcg tgacccacgt ggcatgatgg
    25741 gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc ttgcacaatt
    25801 tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt tcaccactag
    25861 caatggttca gtctgttttg aacgaagggg aacgtgaatt tggtgctaca gtgattgata
    25921 tgggggcagg tcaaacgact gtcgctacaa tccgtaatca agaactccag ttcacacata
    25981 ttctccaaga aggtggagat tatgtaacta aagatatctc caaggttttg aaaacctctc
    26041 gcaaattagc ggaaggctta aaactgaatt acggggaagc ctatccgcct cttgcaagca
    26101 aagaaacctt ccaagtagag gttattggag aagtagaagc agtcgaagtg acggaagcct
    26161 acttgtcaga aattatttct gcacgaatca agcacatcct tgaacaaatc aagcaagaat
    26221 tagatagaag gcgtctattg gacctccctg gtggtattgt cttaatcggt gggaatgcca
    26281 ttttaccagg tatggttgag cttgctcagg aagtctttgg cgtccgtgtc aagctttatg
    26341 ttccaaatca agttggtatc cgtaatccag cctttgcgca tgtgattagt ttatcagaat
    26401 ttgcgggtca attaacagaa gttaatcttt tggctcaggg agcgataaaa ggtgagaatg
    26461 acttaagtca tcagccaatt agttttggtg ggatgctgca aaaaacagct cagtttgtac
    26521 aatcaacgcc tgttcaacca gctcctgctc cagaagtaga gccggtggcg cctacagaac
    26581 caatggcgga tttccaacaa gcttcacaaa ataaaccgaa attagcagat cgtttccgtg
    26641 gcttgatcgg aagcatgttt gacgaataaa gaggaaaaat aaattatgac attttcattt
    26701 gatacagctg ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg aggtggtggc
    26761 aatgccatca accgtatggt cgacgaaggt gttacaggcg tagaatttat cgcagcaaac
    26821 acagatgtac aagcattgag tagtacaaaa gctgagactg ttattcagtt gggacctaaa
    26881 ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc cgctgaagaa
    26941 agcgaagaaa cactgacgga agctattagt ggtgccgata tggtcttcat cactgctggt
    27001 atgggaggag gctctggaac tggagctgct cctgttattg ctcgtatcgc caaagattta
    27061 ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag taagcgtgga
    27121 caatttgctg tagaaggaat caatcaactt cgtgagcatg tagacactct attgattatc
    27181 tcaaacaaca atttgcttga aattgttgat aagaaaacac cgcttttgga ggctcttagc
    27241 gaagcggata acgttcttcg tcaaggtgtt caagggatta ccgatttgat taccaatcca
    27301 ggattgatta accttgactt tgccgatgtg aaaacggtaa tggcaaacaa agggaatgct
    27361 cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc acgtaaggca
    27421 atctattcac cacttcttga aacaactatt gacggtgctg aggatgttat cgtcaacgtt
    27481 actggtggtc ttgacttaac cttgattgag gcagaagagg cttcacaaat tgtgaaccag
    27541 gcagcaggtc aaggagtgaa catctggctc ggtacttcaa ttgatgaaag tatgcgtgat
    27601 gaaattcgtg taacagttgt cgcaacgggt gttcgtcaag accgcgtaga aaaggttgtg
    27661 gctccacaag ctagatctgc tactaactac cgtgagacag tgaaaccagc tcattcacat
    27721 ggctttgatc gtcattttga tatggcagaa acagttgaat tgccaaaaca aaatccacgt
    27781 cgtttggaac caactcaggc atctgctttt ggtgattggg atcttcgccg tgaatcgatt
    27841 gttcgtacaa cagattcagt cgtttctcca gtcgagcgct ttgaagcccc aatttcacaa
    27901 gatgaagatg aattggatac acctccattt ttcaaaaatc gttaagtaaa tgaatgtaaa
    27961 agaaaataca gaacttgttt ttcgagaagt tgcagaggct agtctgagtg ctcatcgaga
    28021 gagtggttcg gtctctgtca ttgcagttac caagtatgta gatgtaccga cagcggaagc
    28081 cttgcttccg ctaggtgttc atcatatcgg tgaaaatcgt gtagataagt ttctggaaaa
    28141 atatgaagct ttaaaagatc gagatgtgac ttggcatttg attggtacct tgcaaagacg
    28201 taaggtgaaa gatgtcattc aatacgttga ttatttccat gcattggact cagtaaagct
    28261 agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc aagtaaatat
    28321 ttctaaagaa gaaagcaaac acggtttttc gagagaggaa ctgctggaaa tcttgccaga
    28381 gttagccaga ctagataaga ttgaatatgt tggtttaatg acgatggcac cttttgaggc
    28441 tagcagtgag cagttgaaag agattttcaa ggcggcccaa gatttacaaa gagaaattca
    28501 agagaaacaa attccaaata tgcctatgac cgagttaagt atgggaatga gtcgtgatta
    28561 taaagaagcg attcaattcg gttccacttt tgttcgtata ggtacatcat tttttaagta
    28621 ggagagaacc atgtctttaa aagatagatt cgatagattt atagattatt ttacggagga
    28681 tgaggattca agtctccctt atgaaaaaag agatgagcct gtgtttactc cagtaaattc
    28741 ttcacaggaa ccggctctcc caatgaatca accttcacag tcggctggta caaaagagaa
    28801 caatatcacc agacttcatg caagacaaca ggaattggca aatcagagtc agcgtgcaac
    28861 ggataaggtc attatagatg ttcgttatcc tagaaaatat gaggatgcaa cagaaattgt
    28921 tgatttattg gcaggaaacg aaagtatctt gattgatttt cagtatatga cagaggtgca
    28981 ggctcgtcgt tgtttggact atttggatgg agcttgtcat gttttagctg gaaatttgaa
    29041 aaaggtagct tctaccatgt atttgttgac accagttaat gttattgtaa atgttgaaga
    29101 tatccgttta ccagatgaag atcaacaggg tgagttcggt tttgatatga agcgaaatag
    29161 agtacgataa tgattttttt aattcgtatg atttataatg cagtggatat ttactccctg
    29221 attttggtag ccttcgctgt catgtcttgg tttccaggtg cctacgaatc cagtttaggt
    29281 cgttggattg tagcgttggt gaaaccagta cttgctccct tgcaacgcct gcctttacag
    29341 atagcgggtc ttgatttatc tgtttgggtc gcgattgttt tggttcgatt tttaggagaa
    29401 aacctagtgc gttttctggc gatgatagga tgaataaagg gatttatcag catttctcca
    29461 tagaagatcg tccatttctt gacaagggaa tggaatggat aaagaaggta gaagatagct
    29521 atgctccttt tttaactcct tttatcaatc ctcatcagga gaagctatta aagattttgg
    29581 ccaaaaccta tggtcttgct tgtagcagta gtggggaatt cgtctcgagt gagtatgttc
    29641 gagttttatt atacccagat tatttccaac cagagttttc agattttgaa atatctctcc
    29701 aagaaattgt gtattccaat aaatttgaac atttaacgca tgctaagatt ttagggacag
    29761 tcatcaatca attagggatt gaacggaaac tttttggaga tatcctagta gatgaagaac
    29821 gggcgcagat tatgattaat cagcagtttc ttcttctctt tcaagatgga ctaaagaaaa
    29881 ttggtcgtat acctgtttcg ctggaggaac gtcctttcac cgagaaaata gataagctag
    29941 aacagtatcg agaactggat ttatctgtgt ctagttttcg attagatgtt cttttatcaa
    30001 atgttttgaa actatctagg aatcaagcaa accagttgat tgaaaagaaa cttgtccaag
    30061 taaattatca tgtggtagac aaatcagatt acactgttca agttggagac ttgattagtg
    30121 tgagaaaatt tggtcgcttg agattacttc aagataaggg acaaacgaaa aaagagaaga
    30181 aaaaaataac cgtccagtta ttattaagta agtgaggaat agaatgccaa ttacatcatt
    30241 agaaataaag gacaagactt ttggaactcg attcagaggt tttgatccag aagaagtcga
    30301 tgaattttta gatattgtgg ttcgtgatta cgaagatctt gtgcgtgcga atcatgataa
    30361 aaatttgcgt attaagagtt tagaagagcg tttgtcttac tttgatgaaa taaaagattc
    30421 attgagccag tctgtattga ttgctcagga tacagctgag agagtgaaac aggcggcgca
    30481 tgaacgttca aacaatatca ttcatcaagc agagcaagat gcgcaacgct tgttggaaga
    30541 agctaaatat aaggcaaacg agattcttcg tcaagcaact gataatgcta agaaagtcgc
    30601 tgttgaaaca gaagaattga agaacaagag ccgtgtcttc caccaacgtc tcaaatctac
    30661 aattgagagt cagttggcta ttgttgaatc ttcagattgg gaagatattc tccgtccaac
    30721 agctacttat cttcaaacta gtgatgaagc ctttaaagaa gtggttagcg aagtacttgg
    30781 agaaccgatt ccagctccaa ttgaagaaga accaattgat atgacacgtc agttctctca
    30841 agcagaaatg gaagaattac aagctcgtat tgaggtagcc gataaagaat tgtctgaatt
    30901 tgaagctcag attaaacagg aagtggaaac tccaactcct gtagtgagtc ctcaagttga
    30961 agaagagcct ctgctcatcc agttggccca atgtatgaag aaccagaagt agctccagtg
    31021 catccgacag gtccaacacc agctacagaa actgttgatt cagcaccagg atttgaagca
    31081 ccgcaagaat ccgttacaat tttataagaa acgatgtgag aacaatatct tatccttata
    31141 tttccagcga gcaggagatg gtgtgagtcc tgcattccct aacgataaga ttatcctctc
    31201 aaaaactcaa gtctgaagct agtaagattt gacgtttccc acgttacggg ataagaggga
    31261 gaaagactaa atctttttcc gaataaaggt ggtaccacga ttttcgtcct ttttggaagt
    31321 cgtggttttt aatttgttat tatttataaa ggagatacca tgaaactcaa agataccctt
    31381 aatcttggga aaacagcttt cccaatgcgt gcaggccttc cgaccaaaga gccagtttgg
    31441 caaaaggaat gggaagatgc aaaactttac caacgtcgtc aagaactaaa tgaagggaaa
    31501 ccgcattttg tcttgcatga tggccctcca tacgcaaacg gaaatatcca cgttggacat
    31561 gccatgaatc atatctcaaa agatatcatc attcgttcta agtctatgtc aggttttaac
    31621 gcaccttata tcccaggttg ggatactcat ggtctgccaa tcgagcaagt tttggcaaag
    31681 caaggtgtga agcgcaaaga aatggacttg gttgagtact tgaaactctg tcgtgagtac
    31741 gctctttctc aagtttataa acaacgtgat gatttcaaac gcttggggat gtcaggtgac
    31801 tgggaaaatt tatatgtgac tttaactcca gactatgaag cagcccaaat ccgtgtcttt
    31861 ggtgagatgg ctaataaggg ttatatctac cgtggtgcca agccagttta ctggtcatgg
    31921 tcatctgagt cagcccttgc cgaagcggaa attgaatacc atgatttggt ttcgacttca
    31981 ctttattatg ccaataaggt aaaagatggc aaaggtatcc tagatacaga tacttatatc
    32041 gtagtctgga caacaactcc atttaccatc acagcttctc gtggtttgac tgttggtgca
    32101 gatattgatt acgttttggt tcaacctgct agtgaaactc gtaagtttgt cgttgctgca
    32161 gaattgttga ctagcttgtc tgagaaattt ggctgggctg atgttcaagt gttggcaact
    32221 taccgtggtc aagaactcaa ccacatcgta acagaacacc catgggatac agctgtagat
    32281 gagttggtaa tccttggtga tcacgttacc actgactctg gtacaggtat cgtccataca
    32341 gcccctggtt ttggtgagga cgactacaat gttggtattg ctaatggtct tgaagtcgca
    32401 gtgactgttg acgaacgcgg tatcatgatg gcgaatgctg gtcctgagtt tgaaggtcag
    32461 ttctacgaca aggttgtacc aactgttatt gaaaaacttg gtaacctcct tctagcccaa
    32521 gaagaaatct ctcactcata cccatttgac tggcgtacta agaaaccaat catctggcgt
    32581 gcagttccac aatggtttgc ctcagtttca aaattccgcc aagaaatctt ggatgctatt
    32641 gataaagtta aattccatac agaatggggt aaagtacgtc tatataatat gattcgtgac
    32701 cgtggtgact gggttatctc tcgtcaacgt gcttggggtg ttccacttcc aatcttctat
    32761 gcagaagacg gtacagctat catgacagct gagactattg aacatgtggc gcaactcttt
    32821 gaagtacatg gttcaagcat ttggtgggaa cgtgatgcca aagacctctt accagaagga
    32881 tttacacatc caggttctcc aaatggggag ttcaagaaag aaacagatat tatggatgta
    32941 tggtttgact caggttcatc atggaatggt gttttggtaa atcgtccaaa tctgacttat
    33001 ccagctgacc tttaccttga aggttctgac caataccgtg gttggttcaa ctcatcactc
    33061 attacatctg ttgccaacca tggcgtagca ccttacaaac aaatcttgtc acaaggtttt
    33121 acccttgatg gtaaaggtga gaagatgtct aaatcacttg gaaataccat tgctccaagt
    33181 gatgttgaaa aacaatttgg tgcagaaatc ttgcgtctct gggtaacaag tgttgactca
    33241 agcaatgacg tgcgtatctc tatggatatt ttgagccaag tttctgaaac ttaccgtaag
    33301 attcgtaaca ctcttcgttt cttgattgcc aatacatctg actttaaccc agctcaagat
    33361 gtagtcgctt acgatgaact tcgttcagtt gataagtaca tgactattcg ctttaaccag
    33421 cttgtcaaga ccattcgtga tgcctatgcg gactttgaat tcttgacaat ctacaaggcc
    33481 ttggtgaact ttatcaacgt tgacttgtca gccttctacc ttgattttgc caaagatgtt
    33541 gtttacattg aaggtgccaa atcattggaa cgccgtcaaa tgcagactgt tttctatgac
    33601 attcttgtca aaatcaccaa actcttgaca ccaatccttc ctcacactgc ggaagaaatc
    33661 tggtcatatc ttgagtttga agctgaagac ttcgttcaat tgtcagaatt gccagaagct
    33721 caaacttttg ctaatcaaga agaagtcttg gatacatggg cagccttcat ggacttccgt
    33781 ggacaagctc aaaaagcctt ggaagaagct cgtaatgcaa aagttatcgg gaaatcgctt
    33841 gaagcacact tgacagttta tccaaatgaa gttgtgaaaa ctctactcga agcagtaaac
    33901 agcaatgtgg ctcaactttt gatcgtgtca gacttgacca tcgcagaagg gccagctcca
    33961 gaagctgccc ttagcttcga agatgtagcc ttcacagttg aacgcgctgc aggtcaagta
    34021 tgtgaccgtt gccgtcgtat cgacccaaca acagcagaac gcagctacca ggcagtcatc
    34081 tgtgaccact gtgcaagcat cgtagaagaa aactttgcgg aagcagtcgc agaaggattt
    34141 gaagagaaat aaggttgaaa agtctaggca aaattcaatt tgagaagaaa agacaactaa
    34201 ttttatagtc tattaaacgc attgtatcac gtttttgaat acctgatatg atgcgttttt
    34261 tatttatttt aaaaatttgc gaggtatgac tttttatact caacaagaat caaagagaaa
    34321 cttagcaagc taacagtagt aagataaaat aggaatttga tattagggat aagattgcta
    34381 aatagtgtaa tatttttaca ataataaatt tatatagtta tttttggttt ctgaaaagta
    34441 ttatatttta tttcatatta tacaaatttt tattttataa tatcagaaaa tacttttttt
    34501 aaaagcaaat atgatacaat tttatttgaa aaaaataaaa aaggagattt tattatgaaa
    34561 ttaaaaacac ttgctttaat tagtggtatc gtcggtcttg tgggaggaat tttacttctt
    34621 attggtcctt ttgtcttgtt gggaacagcg gtaaacacag ttgctacaac tcttaatgga
    34681 ggagctactg caggggcttt ttcaggtgtt gccttactct tgaatgcctt gaagattgca
    34741 aatcttgttc ttggtatcat tgctattgtt tactataaag gagataatcg tgtaggtgca
    34801 gctccgtctg tactaatgat tgtttttggt ggagttagtc tcattccatt cttaggatgg
    34861 gttgggggga ttcttgttat tatcggagga tctctattcc ttgcaacatt gaagaaattc
    34921 aaatcagaag aataaaaggt attttagcat gaaaagaaca aaaaagttta tcggtatagg
    34981 agtagctcta ttatctcttt ttcttctagt tgcatgtgga acataaagtt caaaggatac
    35041 ttcaacaagt aatgatgaga agacagtagc aacatccaat agttcaaaag aaacaatcac
    35101 tttcgataca ccggttgtaa cagacgatgt gattgaatca atacgcactt atgcagatta
    35161 tatagatctt tataaaaata tttttgatga ttattttact aaagctgagg aaggtttcaa
    35221 aggcacagct atggaaaata atgactcgtt tactaaacta aaagagtcaa ctcaaaaatt
    35281 attcgatgcg cagaaaaaaa ggttaaataa tgaagataga atagaaacaa ctaaaaacaa
    35341 tgtgattgcc aaacattgtc aaacagtcct ttcctttttg gttttgacta gcttttttgt
    35401 gaaaaattgt gtaaaataga atagataaac gaggggaaac ctcggaaaat ttaaaggaga
    35461 atccatctaa tggtaaaatt ggtttttgct cgccacggtg agtctgaatg gaacaaagct
    35521 aaccttttca ctggttgggc tgatgttgat ttgtctgaaa aaggtacaca acaagcgatt
    35581 gacgctggta aattgatcaa agaagctggt atcaaatttg accaagctta cacttcagta
    35641 ttgaaacgtg ctatcaaaac aactaacttg gctcttgaag cttctgacca attgtgggtt
    35701 ccagttgaaa aatcatggcg cttgaacgaa cgtcactacg gtggtttgac tggtaaaaat
    35761 aaagctgaag ctgctgaaca atttggtgat gagcaagttc acatctggcg tcgttcatac
    35821 gatgtattgc ctccaaatat ggaccgtgat gatgagcact cagctcacac agaccgtcgt
    35881 tatgcttcac ttgacgactc agtaatccca gatgctgaaa acttgaaagt gactttggaa
    35941 cgtgctcttc cattctggga agataaaatc gctccagctc ttaaagatgg taaaaacgta
    36001 ttcgtaggag ctcacggtaa ctcaatccgt gcccttgtaa aacacatcaa aggtttgtca
    36061 gatgacgaga tcatggacgt ggaaatccct aacttcccac cattggtatt cgaattcgac
    36121 gaaaaattga acgtcgtttc tgaatactac cttggaaaat aaaaaattgt aagtctagaa
    36181 ttgatttcta ggctttttat gttagtatgg aagtatgata aggaataaaa aacaagatta
    36241 tgtactggcc tacaagcaac cagtttcaac cacttacatg ggttgggaag aagaagcttt
    36301 accgataggc aatggttctt taggagcaaa agtatttggc cttatagggg ctgaacggat
    36361 tcaatttaat gaaaaaagtc tctggtctgg aggtccactt cctgatagtt cagattatca
    36421 gggtggaaat cttcaggatc agtatgtttt tttagctgag attcggcagg ctttggagaa
    36481 gagagattac aatctggcta aggaactggc tgagcagcac ctaattgggc caaaaacgag
    36541 tcaatatggg acctatctgt cttttgggga tattcacatt gagttcagcc agcaaggtac
    36601 gactttgtct caggtgacgg actatcagag acagctgaat attagtaagg cacttgtgac
    36661 gacttcttat gtctataagg gaacgcgatt tgaacgtgaa gcttttgcga gttttccaga
    36721 tgatctcttg gttcagcgtt ttactaagga aggggcggaa actctagatt ttactataga
    36781 actatccttg acctgtgatt tggcttctga tggaaagtat gagcaggaaa aatctgatta
    36841 caaggagtgt aagttggata ttactgattc tcatatcttg atgaagggaa gagttaagga
    36901 taatgatctg cggtttgcta gttatctagc ttgggaaacg gatggagata ttagagtttg
    36961 gtcagatagg gttcagatat caggagccag ttatgccaat ctcttcttgg ccgctaagac
    37021 ggattttgcc caaaatcctg ctagcaatta tcgcaagaaa ctagatttag agcaacaggt
    37081 gatagacttg gtggacacag ctaaagaaaa gggctatacc caattgaaat caaggcatat
    37141 cgaggactac caagccttat tccagcgtgt tcaattggat ttggaagcta atgttgacgc
    37201 attcactaca gatgatttgt taaaaaatta taagccacaa gaagggcagg ctttggagga
    37261 gctgttcttc cagtatggac ggtatttatt gattagttcg tccagagact gcccagatgc
    37321 tctaccagct aacctacagg gagtctggaa tgcggtcgac aatcctcctt ggaattcgga
    37381 ctatcactta aatgtcaatc tgcagatgaa ttattggcca gcctatgtta ccaatctcct
    37441 agagacggtc tttccagtca tcaactatgt agatgatttg cgtgtctatg gtcgtctagc
    37501 ggctgtaaag tatgcaggaa tcgtctctca gaaaggtgag gagaatggtt ggttggttca
    37561 tactcaagcg actccctttg gttggacggc acctggttgg gattactatt ggggttggtc
    37621 accagctgcc aatgcgtgga tgatgcaaac cgtttatgaa gcctattcat tttataggga
    37681 ccaagactat ctcagggaga aaatttatcc catgttgagg gaaacggttc gtttttggaa
    37741 tgccttttta cataaggatc agcaggcgca gcgttgggtg tcttctccgt cttattcccc
    37801 agaacatggg ccgatttcga ttggcaatac ttatgaccaa tctctgattt ggcagttatt
    37861 tcatgatttt attcaggctg ctcaggaatt gggactggat gaggacttgt tgactgaggt
    37921 taaggagaag tctgatttac taaatccttt gcaaatcact caatctggtc gaatcaggga
    37981 gtggtatgag gaggaagagc agtattttca aaatgagaaa gtggaggccc agcatcggca
    38041 cgcttcccat ctagtgggac tctatcctgg caatctcttt agctacaagg gacaagagta
    38101 tattgaagcg gtacgtgcta gcctcaatga tcgtggagat ggcggcacag gctggtccaa
    38161 ggctaataag atcaatctct gggcgcgttt gggagatggc aatcgagccc ataaattatt
    38221 ggcagagcag ttaaagacat ccaccttgcc aaatctttgg tgtagccatc ctccttttca
    38281 gatagatggt aattttggtg ctactagtgg catggcagaa atgttactcc agtctcatgc
    38341 agcttatctg gtacctctag ctgccctacc tgatgcttgg tcaacaggtt ctgtttcagg
    38401 cttaatggca cgtggacatt ttgaagtgag catgagctgg gaagataaaa aactcttaca
    38461 gttgaccatt ttatcaagga gtggaggaga tttgcgagtt tcttatccag atattgagaa
    38521 gagtgtgatt aaaatgaatc aagaaaaaat aaaagcgaaa tgcatgggga aagattgtat
    38581 ttcggtggca acagcagaag gtgatcttgt tcaattttat ttttaagaag atgttataag
    38641 gcagtaattt gaaactgcct tttaataagg atttaagaat ataagcagtt ttcaactagt
    38701 tgaaaaaacg ttataatgat aataggaagt aatactcaat gaaaatcaaa gagcacaaac
    38761 taggaagcta gccgcaggtt gctcaaaaca gtgttttgag gttgcagatg gaagctgacg
    38821 tggtttgaag agagattttc gaggagtata atttgtttga tagagggtgg gtctgatggc
    38881 ttatattgag atgaaacact gttacaagcg ttatcaggtt ggggacacgg agattgtggc
    38941 caattgtgat gtgaattttg agattgaaaa gggggagctg gttattatcc ttggtgcttc
    39001 aggtgcaggc aagtcaacag ttcttaacct tcttggggga atggatacca atgatgaagg
    39061 ggaaatctgg attgatggtg ttaatattgc ggattatagt tcccaccagc gcaccaatta
    39121 ccgtagaaat gatgtggggt ttgtttttca gttttataat ctagtttcta atctgacagc
    39181 taaggaaaat gtggaactgg cttctgaaat tgtgacagat gccttgaatc ctgatcaggt
    39241 cttgacagat gtaggtctgg ctcatcgtct caataacttt ccagcccagc tttctggagg
    39301 ggagcaacag cgagtctcca ttgcacgcgc ggtagccaaa aatcctaaaa ttctcctttg
    39361 tgatgaaccg actggagcct tggattatca gacgggcaag caggttttga aaattctcca
    39421 agacatgtct cgtcaaaagg gagcgacggt gatcatcgtg actcataatg gagctttggc
    39481 gcccattgct gatcgcgtga ttcaaatgca cgatgccagt gtcaaggatg tggtgctcaa
    39541 ccagcatcct caggatattg acagtttgga gtactagcat gatcaagcga aaaacttatt
    39601 ggaaggactt aattcagtcc ttcacaggct ccaaggggcg ttttttatcc atcttgatcc
    39661 tgatgatgtt gggatctcta gccttagtag gcctcaaagt aaccagtccc aacatggagg
    39721 cgacagctaa tgcttattta acaactgctc aaaccttgga tttggcagtc atgtctaact
    39781 atggcttgga tcaagcagac caagaagaac taaaacagac ggagggcgca gaggtcgagt
    39841 ttggctattt gacagatgtg actatggata atgggcagga tgccattcgg ctgtactcca
    39901 aaccagagcg aatttcaacc tttcagctaa gaaagggacg acttcctcag tcagacaagg
    39961 aaatcgcttt ggccactcat ttgcaaggcc aatacagcgt gggacaggag attagtttta
    40021 aagaaaaaga agagggtcat tcctctttaa aagaccatac ttataccatt actggttttg
    40081 tggattcggc tgaaatcctc tcccagcgag atatgggcta cgcaggaagt ggaagtggga
    40141 ctctgacagc ctatggggtg attttaccta gtcagtttga tcagaaagtc tacaatatag
    40201 ctcgtttgaa atatcaagat ttagcaggtt taaatgcctt ttcatcagct tatgaagaaa
    40261 aatccaagca acatcaggaa gaccttgaac aaactttatc agataatggc aaggtacgtc
    40321 tgcaactttt gaaaaaagaa ggacaagagt ctctagacaa ggggcaagag acccttgaca
    40381 aggctcagac taatttgcag gaaggcaagc gtcgtttagc agctgctcaa gctcgtatac
    40441 aggctcaaga aagtcaacta gccttgtttc ctcaagttca gagagagcag gctagtgctc
    40501 aacttaccca agccaagcag gaattgggca aggaagagga caaactaaag caagctgaac
    40561 aaaatctagc ccaagaaaag gaaaaattag aaaaacatca gcaagtcttg gacgatttgg
    40621 cggagccaag gtatcaggtc tataatcgtc agaccatgcc aggtggtcag ggctatctta
    40681 tgtatagcaa tgcttcatcc agtattcgag cagtgggcaa tatctttcct gtggtacttt
    40741 atgccgtagc atccatggtg acctttacga ccatgactcg ctttgtagac gaagagcgaa
    40801 ctcatgcagg gatttttaag gccttgggtt accgtagtaa ggatattatc accaagtttc
    40861 tcctttatgg actagtagct gggactgtcg gaacggctct aggtagtata cttggtcatt
    40921 atttgctagc cagtgtaatt tcaagtgtca ttacaaaagg catagtggtg ggagaaaccc
    40981 agattcagtt ctattggacc tatagcttac tagctcttgt cttgagttgg ttggcgagtg
    41041 tgttaccagt ctatctggtg gcttggaggg aacttcatgc cgaagcagcc cagcttctac
    41101 ttcctaaacc tcctgtcaaa ggagctaaaa tcttattgga gcgtatcggt tttatctggc
    41161 gtcgtctcag ttttactcat aaggtaacag cccgcaacat ctttcgttat aagcagagaa
    41221 tgttgatgac aatctttggt gtggcaggtt ctgtagctct gctctttgca ggtttgggaa
    41281 tccaatcttc tgtagcagga gttccgtcta aacagtttca acaaatccaa cagtatcaga
    41341 tgcttgtctc tgaaactcct agtgcgacca atcaggacaa ggtagagcta gcagaagtgt
    41401 tgaaagggca ggagatacta gcctaccaga aaatctattc taaaacgcta gacaaggatt
    41461 tcaaaggcaa ggctggtctt caaaacatta ctcttatgat gatagagaag gaagatttga
    41521 ctccctttat ccatcttcaa catcatcagc aggagctgac attaaaagat ggcatcgtta
    41581 ttacagctaa actcgcccag ctggcaggtg tcaaggttgg gcagacttta gaaattgaag
    41641 gtaaggaact aaaggtcgct gctattactg agaactacgt tggtcacttt atttatatga
    41701 gtcaggctag ctatgagcaa ctttacggac agctacccca agccaacact tatctggtct
    41761 cattaaggga taccagtgca actagtatcg aaagtcaggc gggcttgctt atgaatcaat
    41821 ctgcggtgtc cagcgttgtc caaaatgctt cagccattcg actcttcgac tctatcgcta
    41881 gctcactcaa tcagaccatg accatcttgg tcatcgtatc ggttctatta gctattgtca
    41941 tcctttacaa tctgaccaat atcaacgtag ctgagagaat ccgtgaactc tccactatca
    42001 aggttctcgg ttttcataat aatgaagtca ccctctacat ttaccgtgag acgattgtgc
    42061 tgtcccttgt gggaatcgta cttggtctgg tagctggttt ctatttacac caatttttga
    42121 ttcaaatgat ttcgcctgcg actattctct tttatccgca ggtaggctgg gaagtctatg
    42181 taatcccagt ggcagcagta agcatcattt tgaccttgct tggtttcttc gtcaattatt
    42241 atctgagaaa ggttgatatg ttagaagccc tgaaatctgt agagtaaggt agttattttt
    42301 agctgattga acttctattt attaatattc aaaaatcctc cgtttcaaag agcagggaac
    42361 tctttgtgac agaggatttt ttctataggg ctttagcagc tgcaattgcg gcttcgaagt
    42421 ttggctcaga attgatatta tccacgtatt caacgtagcg aatcgtattg tcagtatcga
    42481 ggacaaagac tgcgcgtgct aataggtgcc attcgttgat caagagggca taatcgcgcc
    42541 cgaaagaatg gtcaaagtag tctgaaagca taatggcatt gtcaaggcct tcagcaccgc
    42601 accaacgttt ttgagcaaaa ggtaggtcca ttgaaacagt caatacgacc gtgttgtcca
    42661 gtccagctaa ttcttcatta aaacgacgtg tttgagttga gcagatgcct gtatcgatag
    42721 aaggaacgac actcaggact tttttcttgc catcaaaatc agccagagat tttttagaaa
    42781 gatctgttgt agtaagagaa aaatcaagcg ccttgtcgcc gccttgtagt tgtttacctg
    42841 taaagctcac aggatttccg agaaaagtta ccataggata ctccaatctt ttttcttcca
    42901 ttgtatctga aacagtcaga attttccaat gatttgaccg gaaatgtggg catagaaaaa
    42961 acgccagctc acatgagaat gacgtttttc agaggcttat tttgccaatc cttcagcaat
    43021 cttgtcaagg ttgtatttca tcatgctgta gtagctgtcg ccttctttac cttgttctgc
    43081 gatagagtca gtaaagattt gtgcgtagat tgggatgttt gtgtcttgag aaacagtttt
    43141 cattggacgg tcatccacac ttgattctac aaagagtgat ggaacttttg tttggcgaag
    43201 tttttcaacc aaggtcttga tttgttcagg agttccttct tcttcagtat tgatttccca
    43261 gatgtaggca cttgggacac cataggcttt agagaagtat ttgaatgctc cttcgctggt
    43321 tacaatgagt ttcttttcag cagggatctt attaaattta tccttacttt ctttatcaag
    43381 tttgtctaac ttatcagtat attctttgag atttttttca tagaattctt tattgttagg
    43441 gtctttggcg ctcaattgtt tggcgatatt tttagcaaaa ataataccgt tttcaaggtt
    43501 aagccaagcg tgtgggtctt cttttccttt ttcattttga ccttcaaggt agataacatc
    43561 aacgccgtcg ctgactgcga agtagtcttt gttttcagtt ttcttggcat tttctaccaa
    43621 ttttgtaaac caagcattgc cacctgtttc aaggttgata ccgttataga aaatcaaatc
    43681 agcctcagaa gttttcttaa cgtcttcagg aagtggttcg tattcgtgtg ggtcttgccc
    43741 aatcggaacg atactatgaa ggtcaatttt gtcaccagca atatttttag taatatcagc
    43801 gatgattgag tttgtagcaa caacttttag tttttgacca gaagttgtat ctttttttcc
    43861 gctagcacat gctacaagaa tgattgcaga aagaaagaga acgagtaatg tacctaattt
    43921 tttcattaga tcctccaatt tattagggct ttgcccctta ttttaacaaa tgtttatttt
    43981 tcagtttcaa atatcgttgt ttgggagcga taaagaagct aatgagaaag aaactagcag
    44041 ctgtaagcac gatactagaa cctgccgcaa cattaaaact atagccaata aagagtccca
    44101 aaactgaagc agtagctccg aaggttgagg aaaggaaaat catgcttttc agactattag
    44161 catacagata agcagttgca gctggggtaa tcagcatggc tacaatcagg atagttccga
    44221 cactttgcat ggctgtcaca gacacgagag tcaggagtac catgagaagg tagtgataga
    44281 aattgacagg cattcccatg gctttagcca agagttcatc aaaggaagtt atcaagagtt
    44341 gcttgaagaa aatccagatt aacaagagga tggctgcccc cacacccata gtaataaaca
    44401 tatccgtatc ttggacggcc aggatattac caaaaaggat atggaaaagg tcagttgaac
    44461 ttttagcgac accaatcaag atgataccga gggctaagaa agaagaaaag gtaatgccga
    44521 tggcggtatc gcttttgata atcgagtttc ctttgatgta ggtaatgatg atggcagcta
    44581 gcaatccaaa gacaatggct ccgataaaga agtcaaggcc caagatgaag gagagggcta
    44641 cacctggtaa gacagcatgt gaaatggcat ctcccatgag tgacatcccg cgtagaataa
    44701 tgaaacatcc cacagctcca gctacaatcc cgacgacaat agctgttatc aaggcatttt
    44761 gtaggaaatg gaatttttgc aatccatcga taaattctgc aatcataggt cacctccatt
    44821 gaaaaagagt tgattaccgt aagcttcttt tagattggtt tcggtaaaag tttcttttgt
    44881 tggaccaaag gcaatcactt ctcgattgac aagtaagact tgatcgaagt agtggggaat
    44941 cttgctgagg tcgtggtgaa cgatgagaac cgtcttccca gcttttttca aatctctcag
    45001 cgtattcatg atgatttcct cactgacaga gtcaatccca gcaaagggtt catccaagag
    45061 gatatagtcg gcttcctgca ccaaacatct ggcaatcaag acccgctgga attgacctcc
    45121 agacagttga ctaatttgac gttcagcgta gtcagctagg ccgacgattt caagggcctc
    45181 ttgcactttc ttccaatgtt tagcctttaa acttcgaaag agaggaatag agggaaatag
    45241 tcctaacgag acgcattcct tgaccttgat gggaaagttg tagtcgatat tgattttttg
    45301 ttcgacatag gcaattcggt gtaaggattt tttaacttcc ttgtcatcga gaaatgcctg
    45361 accttgatgt gggataattc ccagcatacc ttttaatagt gttgatttcc cagcgccgtt
    45421 tggaccaatg atgccggtaa ttgttggtcc atggagcact agtgaaatat ccttaagtgc
    45481 caacgtttct ttgtaggaga cactgaggtt ttcgatacgt atcataaact tgtat
//
LOCUS       DAVKBK010000011        42542 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVKBK010000011 DAVKBK010000000
VERSION     DAVKBK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42542
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.011"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(168..1418)
                     /gene="ilvA"
                     /locus_tag="VWX69_000663"
     CDS             complement(168..1418)
                     /gene="ilvA"
                     /locus_tag="VWX69_000663"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU9192049.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHVQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(1533..2555)
                     /gene="ilvC"
                     /locus_tag="VWX69_000664"
     CDS             complement(1533..2555)
                     /gene="ilvC"
                     /locus_tag="VWX69_000664"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9192050.1"
                     /translation="MAVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(2726..3202)
                     /gene="ilvN"
                     /locus_tag="VWX69_000665"
     CDS             complement(2726..3202)
                     /gene="ilvN"
                     /locus_tag="VWX69_000665"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU9192051.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(3195..4895)
                     /locus_tag="VWX69_000666"
     CDS             complement(3195..4895)
                     /locus_tag="VWX69_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU9192052.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGIDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDVSALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAAAELNEFAERYQIPVVTSLLGQGTIATTHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGCRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLTQDLEVITENVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(5095..6762)
                     /locus_tag="VWX69_000667"
     CDS             complement(5095..6762)
                     /locus_tag="VWX69_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU9192053.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINAEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLNELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEAAQVSKP
                     AEEKEYALIAVVAGKGLADIFRSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGLTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSITTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEEGSEELANEIAQEIAEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(6765..7130)
                     /locus_tag="VWX69_000668"
     CDS             complement(6765..7130)
                     /locus_tag="VWX69_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9192054.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVRFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(7287..7475)
                     /locus_tag="VWX69_000669"
     CDS             complement(7287..7475)
                     /locus_tag="VWX69_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU9192055.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(7591..8076)
                     /locus_tag="VWX69_000670"
     CDS             complement(7591..8076)
                     /locus_tag="VWX69_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU9192056.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(8345..9889)
                     /locus_tag="VWX69_000671"
     CDS             complement(8345..9889)
                     /locus_tag="VWX69_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU9192057.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            10102..10404
                     /gene="gatC"
                     /locus_tag="VWX69_000672"
     CDS             10102..10404
                     /gene="gatC"
                     /locus_tag="VWX69_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU9192058.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            10404..11870
                     /gene="gatA"
                     /locus_tag="VWX69_000673"
     CDS             10404..11870
                     /gene="gatA"
                     /locus_tag="VWX69_000673"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU9192059.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWNHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            11870..13312
                     /gene="gatB"
                     /locus_tag="VWX69_000674"
     CDS             11870..13312
                     /gene="gatB"
                     /locus_tag="VWX69_000674"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU9192060.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            13441..14001
                     /gene="efp"
                     /locus_tag="VWX69_000675"
     CDS             13441..14001
                     /gene="efp"
                     /locus_tag="VWX69_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU9192061.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            14023..14412
                     /locus_tag="VWX69_000676"
     CDS             14023..14412
                     /locus_tag="VWX69_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9192062.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            14405..14827
                     /gene="nusB"
                     /locus_tag="VWX69_000677"
     CDS             14405..14827
                     /gene="nusB"
                     /locus_tag="VWX69_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU9192063.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     AVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(14876..15103)
                     /locus_tag="VWX69_000678"
     CDS             complement(14876..15103)
                     /locus_tag="VWX69_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9192064.1"
                     /translation="MLSGLIFGLSHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRL
                     TILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(15594..15779)
                     /gene="briC"
                     /locus_tag="VWX69_000679"
     CDS             complement(15594..15779)
                     /gene="briC"
                     /locus_tag="VWX69_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU9192065.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(15938..16705)
                     /locus_tag="VWX69_000680"
     CDS             complement(15938..16705)
                     /locus_tag="VWX69_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU9192066.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(16702..17568)
                     /locus_tag="VWX69_000681"
     CDS             complement(16702..17568)
                     /locus_tag="VWX69_000681"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU9192067.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(17605..18972)
                     /gene="accC"
                     /locus_tag="VWX69_000682"
     CDS             complement(17605..18972)
                     /gene="accC"
                     /locus_tag="VWX69_000682"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU9192068.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASRNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(18984..19406)
                     /gene="fabZ"
                     /locus_tag="VWX69_000683"
     CDS             complement(18984..19406)
                     /gene="fabZ"
                     /locus_tag="VWX69_000683"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU9192069.1"
                     /translation="MIDIQGIKEAIPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(19403..19888)
                     /locus_tag="VWX69_000684"
     CDS             complement(19403..19888)
                     /locus_tag="VWX69_000684"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU9192070.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(19891..21126)
                     /gene="fabF"
                     /locus_tag="VWX69_000685"
     CDS             complement(19891..21126)
                     /gene="fabF"
                     /locus_tag="VWX69_000685"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU9192071.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(21148..21879)
                     /gene="fabG"
                     /locus_tag="VWX69_000686"
     CDS             complement(21148..21879)
                     /gene="fabG"
                     /locus_tag="VWX69_000686"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU9192072.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(21913..22833)
                     /gene="fabD"
                     /locus_tag="VWX69_000687"
     CDS             complement(21913..22833)
                     /gene="fabD"
                     /locus_tag="VWX69_000687"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU9192073.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTSLLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTTHLAHVEDQASLVALLKK"
     gene            complement(22826..23800)
                     /gene="fabK"
                     /locus_tag="VWX69_000688"
     CDS             complement(22826..23800)
                     /gene="fabK"
                     /locus_tag="VWX69_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU9192074.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(23919..24143)
                     /locus_tag="VWX69_000689"
     CDS             complement(23919..24143)
                     /locus_tag="VWX69_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9192075.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(24203..25177)
                     /locus_tag="VWX69_000690"
     CDS             complement(24203..25177)
                     /locus_tag="VWX69_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU9192076.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(25177..25611)
                     /locus_tag="VWX69_000691"
     CDS             complement(25177..25611)
                     /locus_tag="VWX69_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9192077.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(25705..26490)
                     /locus_tag="VWX69_000692"
     CDS             complement(25705..26490)
                     /locus_tag="VWX69_000692"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU9192078.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            26859..28223
                     /locus_tag="VWX69_000693"
     CDS             26859..28223
                     /locus_tag="VWX69_000693"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU9192079.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            28226..28597
                     /locus_tag="VWX69_000694"
     CDS             28226..28597
                     /locus_tag="VWX69_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU9192080.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            28811..30085
                     /gene="serS"
                     /locus_tag="VWX69_000695"
     CDS             28811..30085
                     /gene="serS"
                     /locus_tag="VWX69_000695"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU9192081.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVEAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(30110..31009)
                     /locus_tag="VWX69_000696"
     CDS             complement(30110..31009)
                     /locus_tag="VWX69_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU9192082.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(31119..31667)
                     /locus_tag="VWX69_000697"
     CDS             complement(31119..31667)
                     /locus_tag="VWX69_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU9192083.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(31885..33207)
                     /locus_tag="VWX69_000698"
     CDS             complement(31885..33207)
                     /locus_tag="VWX69_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU9192084.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFTFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(33298..33386)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(33550..35886)
                     /locus_tag="VWX69_000699"
     CDS             complement(33550..35886)
                     /locus_tag="VWX69_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU9192085.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKGQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQIGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(35990..36538)
                     /locus_tag="VWX69_000700"
     CDS             complement(35990..36538)
                     /locus_tag="VWX69_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU9192086.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(36535..36837)
                     /gene="zapA"
                     /locus_tag="VWX69_000701"
     CDS             complement(36535..36837)
                     /gene="zapA"
                     /locus_tag="VWX69_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU9192087.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            36924..37805
                     /locus_tag="VWX69_000702"
     CDS             36924..37805
                     /locus_tag="VWX69_000702"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU9192088.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            37809..38423
                     /gene="lepB"
                     /locus_tag="VWX69_000703"
     CDS             37809..38423
                     /gene="lepB"
                     /locus_tag="VWX69_000703"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU9192089.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            38657..41023
                     /locus_tag="VWX69_000704"
     CDS             38657..41023
                     /locus_tag="VWX69_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU9192090.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNSIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(41071..42354)
                     /locus_tag="VWX69_000705"
     CDS             complement(41071..42354)
                     /locus_tag="VWX69_000705"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU9192091.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        12314 a         9797 c         8166 g        12265 t
ORIGIN      
        1 ttttttatta ttataaaatg aaacaaaaat aataggtact ataataagtt gtagtagaaa
       61 tagtaggata gttttcctaa gttcatagga atcgccccct ttcttcatcc tcattatagc
      121 acctatacat cggttgtgca aataatatga tattttttta ttagtcctca gacaagcata
      181 ttatagagcg tttcattacc atttaagtta atataagctg gatcaaaacc ttccattcga
      241 cgaatcaatc ctgcataatc atgcttatct gctaaggcaa tcccaatcaa tactggtcct
      301 gttcccttgc tagctcgttt gatatactca aaacgtgtga tatcatcatt tggccctagg
      361 atatcattta caaattcacg caaagctcct ggacgctgtg ggaagttgac cacaaagtaa
      421 tgcttaatcc catcataaat caaggcacgc tcttccattt ctggcatacg gttgatatca
      481 ttatttcctc cagaaatgat acaacaaatg gttttcccct tgatatattc agctaaaacc
      541 tctaaagagg cgatactagc tgctccagca ggctctgcta caatcccttg tttagagtag
      601 agatcaatca aggtttcaga aatcaacccc tcatcaacac ctactaaggt ttgaacatgt
      661 tggcgagttg cctcataggt caactgcccc accttttgta cagcaatccc atccgcaaat
      721 ttatcaattt ccttgagttt gactggacca ccagcttcaa aggcagcctt catggaacgc
      781 gctccattcg cctctactcc gataacctcg atctctggac ttgtttcctt gatataggta
      841 gaaaccccag caatgagacc gccaccacca acaggaacca agacagcatc aaaatcaatg
      901 gattcttttc gagcttcttc taaaatctca taagcaacag tcccttgacc tgcttggaca
      961 tgggcatcat caaagggatc aataaaggta cgattttcag aaactgtaaa ttcttgagct
     1021 gccttagcag aagcatcaaa ggtatctcca actagtttaa tggtcacgaa gtccccacca
     1081 aaaaagcgaa cctgcccaat cttttgctgc ggagtagtaa tgggcatgaa aatagtagca
     1141 ggaattttca tctcattaca agtataggca actccctgcg catgatttcc cgcagaagca
     1201 cagactaccc cacgctcacg ctcttccttg ctgagctgag aaatagcata ataggcacca
     1261 cgaattttaa aagaacgaac acgttgggca ttttcctttt tcaaataaat cttagcacca
     1321 tacttctctg ataaataatg gtcataatcc agtggggtat tcacaaccac accgttcaag
     1381 accttgtgag ccttgatgat atcttttgaa cttaacatct ttttctccta gactattcat
     1441 actatcacaa tccatcctct aaaaagagag atgaattgat tataaaagcg agttaggtcc
     1501 ccccaactcg ccttcacctt aatttctata aattagttat agattttgaa tgcatcatcg
     1561 tcgtttttac caacgaatgg cattgcttta cgcaattctg caccaacttt ttcaatttca
     1621 aggttagctg cttgttcacg gtaagcagtc aattttggac gtccagcttt atagtcattc
     1681 acaaagtcat ttgcaaattt accattttgg atatcagcca agacagcttt catgttttct
     1741 ttaacttgct cagtgattac acgtggacct gatacatagt caccgtattc agcagtgttt
     1801 gaaattgatt gacgcatttt cttgaatcca ccttcgtaga tcaaatcaac gatcaatttc
     1861 atttcgtgaa gaacttcaaa gtaagccaat tctggggcgt agcctgcttc tgtcaaaact
     1921 tcgaaacctg cttcgataag ggcagtcaaa ccaccacaaa gtacagcttg ttcaccaaac
     1981 aaatcttctt cagtttcttc tttgtatgtt gtttcaagaa gacctacacg agcagctcca
     2041 acacctttac accagtccat agcaatgttt ttcgcatttc ctgttgcatc ttgatatact
     2101 gcgtaaagag ctggaacacc aaatccttct tcgtaagtac gacgtaccaa gtgtcctggt
     2161 cctttaggag cacacatgaa gacatctaca tctgcaggaa ctttgataaa ttcaaagtgg
     2221 atgttgaaac catgagcaaa tccaactgcg tttccagctt ccaagtttgg agcgatttct
     2281 gcttcgtaca gttcttgttg gatttcatct ggtgccaaaa tcatgataac atcagccaat
     2341 ttagtagctt ctgctactgt gtaagtgtca aatccatctt cttttgcttt gtcaaaagat
     2401 ttacctggac gtacaccgat aataacgtca cgacctgaat cacgcaagtt ttgagcatgc
     2461 gcatgtcctt gtgaaccata accgataacg gcgatttttt taccgtcaag tgctgctact
     2521 ttaacatctt tttcgtattc catttgaact gccatagttt tttctctctt ttctattatt
     2581 tattgccttt taggctggtt taacaaattt aaaatatttt tatactcaat gaaaatcaaa
     2641 gagcaaatta ggaagctaga cgcaggctgt acttgagtac ggcaaggcaa agctgacgtg
     2701 atttgaattt aattttcgaa gagtattaat cgcgggtaaa tccagttgca ccagttctag
     2761 caatattgcg aataccgtat ggtcgaatga ctcgcaatag agcttcactc ttttcagcat
     2821 ttcctgtcat ctgaatggta attgagcttg gtgctacgtc taccaccgtt gctcggaaag
     2881 gttgaataat cgctagaatc tcagctcgct tctcagctgg cgctgacatc ttaaccaaaa
     2941 tcacctcgcg ctccaaatga ggcttgtctg taatatcacg aatgcgaatc acatcaatct
     3001 gacgattgag ctgcttaatg atttgctcca cttcatcatg tgaagctaca tcaataataa
     3061 tggtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt tcgatattaa
     3121 cctgacgacg agacagaacg ccagtaaagc gattgaggac tcctgaacga ttttgtagtt
     3181 ttgctgttaa cattctacgc atggaacttc acccccaaca tctcatgatt actcttacca
     3241 gctggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcgat tagcatagga
     3301 acattctcag tgatgacttc aagatcttga gtcaaggtct caggattatc aaacttatag
     3361 tttttaatgc cataagcctg tgccatcaat tggaaatcag gaagggtatc aaagactgac
     3421 tctgatgttc taccttcata gaaggattcc tgccactggc gaaccattcc aagtgagtgg
     3481 ttgttcagca taaccacctt gattggcacc ttgtaaatgt ttaaaatagc caattcctgg
     3541 ttggtcattt ggaaaccacc atccccaaca aacaagacta cttccttatc tgggttagca
     3601 attttagcac cgattgctgc tggaattccg aatcccatgg ttcccaaacc gcctgaagtc
     3661 actaactgac gttcattttg gtagggataa tactgggctg tccacatttg gtgttgacca
     3721 acgtctgtta ccacaatggc atcaccattt gtcaactcac caatgcgttc aataacggct
     3781 tgaggttgaa ccacacgttc tttcttatca taagaacgaa cacggttctt gtctttagtg
     3841 actttctcaa tccatttctc agtattgtta tgaacggttg gttcggccag caacatttgc
     3901 aaggctttct tcgcatctcc aactacagga atatccgcgc tgataatctt gccaatctcg
     3961 gctgggtcaa tatcaatatg agcaacctta gcattcttag caaaagtctt aggattccct
     4021 gtcaagcggt catcaaaacg gcaaccaata ctaatcataa agtcagcttc cgtcatggca
     4081 atattagctg cgaaagatcc gtgcatgcct cccattccaa ggaagagtgg gtgagtcgtt
     4141 gcaatcgtac cttgccctaa aagactggtt accactggaa tctgatagcg ttctgcaaat
     4201 tcatttaatt ccgcagctgc ttcagcataa ctaattccac caccagctag caagactggt
     4261 tttttagcct tagataattg cttcaagatt ttcttaattt gcatatcatt tggctcaaga
     4321 gttggctgat agcttggtag attgacttct ggtgaataga tgaagtctgt ttctaaagca
     4381 gatacgtctt taggtaggtc aatgacaact ggccctggtc gacctgtagt tgcaatatgg
     4441 acagcttccg taatgatacg cggaatatca gccgtctcac gaacttggta attgtactta
     4501 gtgattggca tggtaattcc cacgatatct gcctcctgaa aggcatcttt cccaatccct
     4561 gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat ggcatctgca
     4621 atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac acccaacttt
     4681 ccagttgatt tggcataacc ttcagcttca tgcaaacaac cttgctcatg gcgtcctaga
     4741 atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaagac cgcaccacca
     4801 ggataaccaa agatggtatc aattcctaaa tcacgaagtg tttccaaaac taggtccgac
     4861 cccgtcttag gagattctaa actgattttc tccattgttc ccctttctct tcacttaaaa
     4921 ataacttgtt actatcatac cattttttca agatttttca agagaaaaga agaaattttc
     4981 tgaattttct attttaacgt tttttgatga atattctttt tgtttttatt taaaagatat
     5041 cgattccatt attcaaaatg aaaaaagaac tgatttctca gtccttcatt aatcttattc
     5101 cacactaaat aggtatgggt aaacaggttg ttgaccttgg tgaatctcaa cttcaacgtc
     5161 ttcgaattct tctgcgattt cttgagcaat ttcattagca agttcttcgc ttccttcttc
     5221 accgacatag aaggttacga tttcactatc ttcatccaac atatgtttca atgtttcagt
     5281 caaggtttgg tgcatgtcag ggtttgacac gaggattttc ccatcgacca taccaagatt
     5341 gtcattttca tggatttcta aaccatcaat tgttgtatca cgcacggctg ttgtgatgct
     5401 tccgctaacg acatcgctaa gggctgcagt catacgctct tggttttctt cgatggactt
     5461 acttgggtca aaggcaagaa gactagtcaa tccttgagga agagtacgag cttccaccac
     5521 tactgctggt tgttccaaaa cttctgctgc agattgagct gccatgaaga tattcttgtt
     5581 gtttggcaag aagataatgt tacgagcgtt gacctgttca acagccttga taaagtcttc
     5641 tgttgaaggg ttcatggttt gaccgccttc gataacataa tctacacctt gagaacggaa
     5701 gatatctgct agacctttac cagccaccac agcaatcaaa gcatactctt tttcttcagc
     5761 tggcttgcta acttgggcag cttctttctc aacctgtgct tcgtgttggt tacgcatatt
     5821 gtcaactttt accttgacca agctaccata tttgagacct tcttgcataa caagtcctgg
     5881 atcttctgta tggacatgga ctttgacgat ttcatcatca ttgacaacaa ggagagaatc
     5941 tccaagttca ttcaagtagt tacggaactc gtcgtagtca aaatctttgg cataagttgg
     6001 accttgctta agagctacca tgatttcagt acagtaacca aatgtgatat cctcagtcgc
     6061 tacgtgacca gctacagact tatggtgctc tgcattgatc atttcactca tgttggcagg
     6121 agtcgctaca aagtcctcag atgcaatata ttcaccagta agggctgaaa ggaacccttc
     6181 gtagatgaag accagtcctt gaccacctga atccacaacg ccaacttcct tcaagactgg
     6241 aagcatatct ggcgttttag ctagagcggt tttagcacct tctaaagctg cacgcattac
     6301 ctcaacagca tcatctgttt gctcagcctt tttcttagca ccgatagcag cgccacgcga
     6361 aactgtcaaa atcgttcctt caactggttt catcacggcc ttataggcaa cttcaacacc
     6421 tgattggaag gcaagggcca agtcttgacc tgttaactcg tctttatcct tgatggcttg
     6481 tgaaaatccg cggaaaagct gagacgtaat aactcctgag ttcccacgcg cacccatcaa
     6541 aagacctttg gcaagaatgc ttgctacctc tccaactgta gaagctggct tgtctgcaac
     6601 ttccttagct ccattttcaa tggtcattcc catatttgta ccagtatctc catctggaac
     6661 tggaaagacg tttaatgaat tgacatattc agcttgctta ttcaagcgag ttgatgcagc
     6721 ctgcaccatt tcttgaaata agctagtagt aatttttgac acggttattc tcctacaact
     6781 ttgatatttt gaatgtagac atttacagtc tgagcggtaa ttccaagttg gttttccaaa
     6841 ctaaaacgaa cacgctcttg aatgtttttt gacacttcgc taatctttgt tccgtagctc
     6901 aacacggtat atacatcaac tgcaatacta ccatcttcgg ccgcctttac gacgacacct
     6961 ttagaataat tttccttacc tagaagggct tggaaattat ctttgagggc atttttacta
     7021 gccataccga ccacaccaaa aatctcagtt gctgctccac ctacgacggt tgcaatcact
     7081 tcatctgtta gttcgatttg accatctttt gtattaattt ttacagtcat cctttttacc
     7141 tcaactagtt gatactctat tttatcatat ttcagcccaa gtgtaaaagc agaatgatgt
     7201 atcagcggat atttactcta tttttcaaac gatgttatac ccacaataaa agaaaaaaga
     7261 ccctaaggtc tcctttgctt ttattattaa acgcgttcaa ctttacctga tttcaaagca
     7321 cgagctgaag cccaaacttt tttaggttta ccatcgataa gaacagtaac tttttgaagg
     7381 tttggtttta cggcacgttt tgtttggttc atcgcgtgtg aacggttgtt tcctgataca
     7441 gtcttacgac ctgtaaagta acatacttta gccattgtgt tttcctccta ttagatctaa
     7501 tatagcggat gtgctagcac cacataccgt actatgttat cacactttct tgttttttgc
     7561 aagggaattg gaagattttt tatttgtgtc ttaaatcagg tcttgcgtga cattttctgc
     7621 tctccacatg ccattgttga ttaacagaac accagaatta aaattatgtg tataaaaatc
     7681 atctctaact gcagctaagg gtatagccgt caagtccaaa tcccacagct catctatcga
     7741 ttttcttaca acaatatctg aatccaaata cagtacacga gactcgctta catactttgg
     7801 aataaaatac ctaaaaaaag ccgcatatga aagtccctca aaggggagac gataaccttt
     7861 cagaatacta ctgtcaatct gaacattcac aatctcacta ttcaaagtct ctagtctttt
     7921 ttccatcaat tggaaccatt ctcgcggaag gtcatcatta aaaacataaa acttaagatt
     7981 ataatgatga acacaaagag attttattgt tgtttcaact ttatccatat aagcattatc
     8041 tgcacctaag acaatcgctt ttttctcttc tttcactctt tatcttattt ctttttattc
     8101 ccatcatatt attcccatca tatgtttcta cgtaaccatt attttcgcct attcgttcgt
     8161 aaaaccatac cagtggagat tttagatgaa gtcccattac ggtttacaat ttttacatta
     8221 cgacacggag ttttacaaat cgatttcatt tgccaaacgt agttagtgag gcagttagct
     8281 agttcgccaa atagcgacta gcgtccaaca atttggaact ttagctccaa ttgttggtac
     8341 tgagtcacat cttctcctct aactctacgt ctggatactt gtccgcaaac cagcggaggg
     8401 caaagtcatt ttcaaagaga aagactggtt ggtcaaaacg gtctttggct aagatattgc
     8461 gacttgacga catccgttca tccaagtcct caggcttgat ccaacgaacg gtctttttac
     8521 ccattgggct catgaccact tccgcattgt attcgccttc catacggtgt ttaaagactt
     8581 caaactggag ttgaccaaca gctcccagca tgtactcacc tgtttggtaa ttcttataaa
     8641 gctgaacggc tccttcttgc accaattgct caatcccctt gtggaaggat ttttgcttca
     8701 taacattctt ggcagaaact ttcatgaaaa tttcaggagt aaaggttggc agtggttcaa
     8761 attcaaactt gttttttcca accgtcaagg tatccccaac ctgataagta ccggtatcgt
     8821 aaaccccgat aatatcacct gccacggcat tgatcacatt ctcacgactt tccgccataa
     8881 actgggtaac attagatagt ttagccccct taccagtacg agggagattg acactcatgc
     8941 cgcgctcaaa ttcgcctgat acgatacgga caaaggcaat acggtcacgg tgacgaggat
     9001 ccatgttggc ttggatttta aagacaaagc ctgagaaatc cttgtcataa ggatccacaa
     9061 tttcaccgtc tgttttcttg tgaccatgtg gttctggagc aaacttgagg aagatttcaa
     9121 ggaaggtctg cacaccaaag tttgtcaggg ctgaaccgaa aaagacaggc gtcaattctc
     9181 cagccagaat agcttcctct gaaaactcat tcccagcttc atttaaaagc tcaatgtcat
     9241 ccttgacttg ctcgtagaaa ggattgctac caaagagttt gtccccgtct tctagactgg
     9301 caaaacgctc atcccctttg taaagctcta aacgttggtt atagaggtca tacaagccct
     9361 caaaggcttt ccccatcccg ataggccagt tcatagggta gctagcaatg cccaagattt
     9421 cttccaattc ttgcaagaga tccaaaggct cacgaccgtc acggtccagc ttgttcataa
     9481 aggtaaaaac tggaatgcca cgatgtttca caacctcaaa caatttcttg gtttgagcct
     9541 cgatcccctt ggcagagtcc acgaccatga ccgcagcatc caccgccatc aaggtacgat
     9601 aggtatcttc tgagaagtcc tcgtgccctg gcgtgtctaa gatattcacg cgcttgccgt
     9661 cgtagtcaaa ttgcataaca gatgaagtaa cagaaatccc acgttgcttc tcgatatcca
     9721 tccagtcaga tttagcaaaa gtccctgttt tcttcccttt taccgtacca gcctcacgaa
     9781 tctcaccccc aaagtagagt aactgctcag tgatggttgt tttccccgcg tccgggtggg
     9841 agataatggc aaaggtacga cgtttcttaa tttcttcttg aatattcata agttctcttt
     9901 ctttgattct ctatttttct tgtttcaata gctgagaatg atttttacat tggattttac
     9961 cattcctttc aatactccat tatatcggat tttagcattt ttttcaattt ctatctcttt
    10021 tcacttcccc ctcccttatt tataggaaaa tatggtaaaa tagaacagac taaaaatcat
    10081 catttcacga aaggatgcaa gatgaaaatt acgcaagaag aggtaacaca cgttgccaat
    10141 ctttcaaaat taagattctc tgaagaagaa actgctgcct ttgcgaccac cttgtctaag
    10201 attgttgaca tggttgaatt gctgggcgaa gttgacacaa ctggtgtcgc acctactacg
    10261 actatggctg accgcaagac tgtactccgc cctgatgtgg ccgaagaagg aacagaccgt
    10321 gatcgcttgt ttaaaaacgt acctgaacaa gacaactact atatcaaggt gccagctatc
    10381 ctagacgatg gaggagatgc ctgatgactt ttaacaataa aactattgaa gagttgcaca
    10441 atctccttgt ctctaaggaa atttctgcaa cagaattgac ccaagcaaca cttgaaaata
    10501 tcaagtctcg tgaggaagcc ctcaattcat ttgtcaccat cgctgaggag caagctcttg
    10561 ttcaagctaa agccattgat gaagctggaa ttgatgctga caatgtcctt tcaggaattc
    10621 cacttgctgt taaggataac atctctacag acggtattct cacaactgct gcctcaaaaa
    10681 tgctctacaa ctatgagcca atctttgatg cgacagctgt tgccaatgca aaaaccaagg
    10741 gcatgattgt cgttggaaag accaacatgg acgaatttgc tatgggtggt tcaggtgaaa
    10801 cttcacacta cggagcaact aaaaacgctt ggaaccacag caaggttcct ggtgggtcat
    10861 caagtggttc tgccgcagct gtagcctcag gacaagttcg cttgtcactt ggttctgata
    10921 ctggtggttc catccgccaa cctgctgcct tcaacggaat cgttggtctc aaaccaacct
    10981 acggaacagt ttcacgtttc ggtctcattg cctttggtag ctcattagac cagattggac
    11041 cttttgctcc tactgttaag gaaaatgccc tcttgctcaa cgctattgcc agcgaagatg
    11101 ctaaagactc tacttctgct cctgtccgca tcgccgactt tacttcaaaa atcggccaag
    11161 acatcaaggg tatgaaaatc gctttgccta aggaatacct aggcgaagga attgatccag
    11221 aggttaagga aacaatctta aacgcggcca aacactttga aaaattgggt gctatcgtcg
    11281 aagaagtcag ccttcctcac tctaaatacg gtgttgccgt ttattacatc atcgcttcat
    11341 cagaagcttc atcaaacttg caacgcttcg acggtatccg ttacggctat cgcgcagaag
    11401 atgcaaccaa ccttgatgaa atctatgtaa acagccgaag ccaaggtttt ggtgaagagg
    11461 taaaacgtcg tatcatgctg ggtactttca gtctttcatc aggttactat gatgcctact
    11521 acaaaaaggc tggtcaagtc cgtaccctca tcattcaaga tttcgaaaaa gtcttcgcgg
    11581 attacgattt gattttgggt ccaactgctc caagtgttgc ctatgacttg gattctctca
    11641 accatgaccc agttgccatg tacttagccg acctattgac catacctgta aacttggcag
    11701 gactgcctgg aatttcgatt cctgctggat tctctcaagg tctacctgtc ggactccaat
    11761 tgattggtcc caagtactct gaggaaacca tttaccaagc tgctgctgct tttgaagcaa
    11821 caacagacta ccacaaacaa caacccgtga tttttggagg tgacaactaa tgaactttga
    11881 aacagtcatc ggacttgaag tccacgtaga gctcaacacc aattcaaaaa tcttctcacc
    11941 tacttctgcc cactttggaa atgaccaaaa tgccaacact aacgtgattg actggtcttt
    12001 cccaggagtt ctaccagttc tcaataaagg ggttgttgat gccggtatca aggctgctct
    12061 tgccctcaac atggacatcc acaaaaagat gcactttgac cgcaagaact acttctatcc
    12121 tgataacccc aaagcctacc aaatttctca gtttgatgaa ccaatcggat ataatggctg
    12181 gattgaagtc aaactagaag acggtacgac caagaaaatc ggtatcgaac gtgcccacct
    12241 agaggaagac gctggtaaaa acacccatgg tacagatggc tactcttatg ttgacctcaa
    12301 ccgccaaggg gttcccttga ttgagattgt atctgaggca gatatgcgtt ctcctgaaga
    12361 agcctatgct tatctgacag ccctcaagga agttatccag tacgctggca tttctgacgt
    12421 taagatggag gaaggttcga tgcgtgtgga tgccaacatc tcccttcgtc cttatggtca
    12481 agagaaattc ggtaccaaga ctgaattgaa gaacctcaac tccttctcaa acgttcgtaa
    12541 aggtcttgaa tacgaagtcc aacgccaggc tgaaattctt cgctcaggtg gtcaaatccg
    12601 ccaagaaaca cgccgttacg atgaagcgaa taaagcaacc atcctcatgc gtgtcaagga
    12661 aggggctgct gactaccgct acttcccaga accagaccta cccctctttg aaatttctga
    12721 cgagtggatt gaggaaatgc ggactgagtt gccagagttt ccaaaagaac gtcgtgcgcg
    12781 ttatgtatct gaccttggtt tatcagacta cgatgctagt cagttgactg ctaataaagt
    12841 cacttctgac ttctttgaaa aagctgttgc cctaggtggt gatgccaaac aagtctctaa
    12901 ctggctccaa ggggaagtcg ctcagttctt gaatgctgaa ggtaaaacac tggaacaaat
    12961 cgaattgaca ccagaaaact tggttgaaat gattgccatc atcgaagacg gtactatttc
    13021 atctaagatt gccaagaaag tctttgtcca tctagctaaa aatggcggtg gcgcgcgtga
    13081 atacgtggaa aaagcaggta tggttcaaat ttcagatcca gctatcttga tcccaatcat
    13141 ccaccaagtc tttgccgata acgaagctgc tgttgccgac ttcaagtcag gcaaacgtaa
    13201 cgccgacaaa gcctttacag gattccttat gaaggcaacc aaaggccaag ccaacccaca
    13261 agttgccctt aaactacttg cacaggaatt ggcgaagttg aaagaaaact agacagaaca
    13321 aaaccagccc taaggttggt tttttcttct ctaccaactc ccaataacta ttttggcttt
    13381 atttccagag tattttatgg taaaatgaag agtaataata tttattaaag aggtaaaaac
    13441 atgattgaag caagtaaatt aaaagctggt atgacctttg aaacagctga cggcaaattg
    13501 attcgcgttt tggaagctag tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg
    13561 aaattgcgtg atgtccgtac tggttctaca tttgacacaa gctaccgtcc agaggaaaaa
    13621 tttgaacaag ctattatcga gactgtccca gctcaatact tgtacaaaat ggatgacaca
    13681 gcatacttca tgaatacaga aacttatgac caatacgaaa tccctgtagt caatgttgaa
    13741 aacgaattgc tttacatcct tgaaaactct gatgtgaaaa tccaattcta cggaactgaa
    13801 gtgatcggtg tcaccgttcc tactactgtt gagttgacag ttgctgaaac tcaaccatct
    13861 atcaaaggtg ctactgttac aggttctggt aaaccagcaa cgatggaaac tggacttgtc
    13921 gtaaacgttc cagacttcat cgaagcagga caaaaactcg ttatcaacac tgcagaagga
    13981 acttacgttt ctcgtgccta atctctagaa agaggtcatt ctatgggaat tgaagaacaa
    14041 cttggcgaaa tcgttatcgc cccacgtgta cttgaaaaaa tcattgctat cgctactgca
    14101 aaggtagagg gtgttcactc tttttcaaac agatcagtgt ctgataccct ttcaaaactt
    14161 tcactcggcc gtggcattta tcttaaaaac gtggacgaag aactcacagc agatatctat
    14221 ctctaccttg agtacggagt aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc
    14281 aaagatgccg tccgtaatat ggctgatgta gaactcgctg ctatcaatat tcacgttgca
    14341 ggtatcgtcc cagataaaac accaaaacca gaattgaaag atctatttga cgaggacttc
    14401 ctcaatgact agtccactat tagaatctag acgccaactc cgtaaatgcg cttttcaagc
    14461 tctcatgagc cttgagttcg gtacggatgt cgaaactgct tgtcgtttcg cctatactca
    14521 tgatcgtgaa gatacggctg tacaacttcc agcctttttg atagacctcg tttctggtgt
    14581 tcaagctaaa aaggaagaac tagataagca aatcactcag catttaaaag caggttggac
    14641 cattgaacgc ttaacgctcg tggagagaaa cctccttcgc ttgggagtct ttgaaatcac
    14701 ttcatttgac actcctcagc tggttgctgt taatgaagct atcgagcttg caaaggactt
    14761 ctccgatcaa aaatctgccc gttttatcaa tggactgctc agccagtttg taacagaaga
    14821 acaataaaaa gaaaaagtgt ttgatatcta tcaaacactt tttctttgcc tcccactatc
    14881 taaaaaaatg ataatagata taattgtaaa caaaaatcca gataggtttt gcatgattga
    14941 gaaagttaaa aaaactatgg cagagaatcg ttaatctcag attgtcggta gaacgataaa
    15001 caagggcaaa aaagaaacca atcagactat aatataataa actaattgga tctctgtgag
    15061 atagtatcaa atgactaagc ccaaagataa ggcctgataa gatgacatct aaataatact
    15121 tggactaggg aaagaaggta ttcataaaat accctctatc aagagtctcc tcaaaaacag
    15181 gaccgatgat tacaggcagg acaaaagata agatagtcga taaaaaggtt ggttgtccat
    15241 ttgaaagaac cacggtaaaa tactcatcat gaatattcct atgattaatc aaatgagcat
    15301 agcgtgccca aaaattaccg agaatctgat aaaccacata agttgcaaat aaggagaaga
    15361 caaatgacca gttccagctc tttttctttt ttaacctcca aattaataga aaaggaaact
    15421 tcccactaat cccactgtta aaataagaga atagacatca gctcctaacc ctaaaatgat
    15481 cgtcacatac aatccaattg tttgtggtaa ataggtagat agtaaaataa taagcaaaaa
    15541 tattccaaat tgtcttagtt tctttgtgtt tctcatcgta cttttttgaa agattaccct
    15601 gttcggaagc cgtacttcca agcatctata taagaattaa gtgccccttg cctcatatag
    15661 ggagcaaatt ctctataata taaccatcta ctatatccat cttcccaaac agcaagacca
    15721 cctgaagttt gctccaagtc ctcagttgaa ataactgtaa atgtttctgt acctgtcatt
    15781 gcaagtacct tcttaaaata gattgttgta ggctcacatt tatagtatat ttcttttttt
    15841 gtctatttta tagtctatct cctcaactgg caatttttcg acctgaattg catttttcca
    15901 taaaaaatga gacctttcta gtctcattta gtcattctta gtattttcta aatcgttgat
    15961 agcgttcttc cagcaactct tctagcggtt tttgtgaaag tctagccagc tccgtttgga
    16021 gttctttttt gacactctta attagttctt tactagaaag tcctacttca gaaatcacct
    16081 tatccaccac gtccatttct aacagttcat gcgaagtgat tttcatcagt tctgctgctt
    16141 ccatggcgcg agtaccgtcc ttccataaaa tggaagcaaa gccttctgga ctgagaatgg
    16201 catagataga attttccagc atccagacac ggtccgcgac agctagagcc agagccccgc
    16261 ctgaaccacc ttcaccgata ataatggcga taataggaac tttcaggtca ctcatttcca
    16321 tgagattgcg agcgatagct tccccttgac cacgttcttc cgctccgaca ccaggataag
    16381 cacctgctgt attgataaag gtcacaactg gacggccaaa tttctcagcc tgtttcatca
    16441 accgcagtgc ctttcggtag ccttctggat gtggttggcc aaaattccgt ttgaggttgt
    16501 cttgcaaact cttgcctttt tggataccaa ccactgttac agcttggtct ccaagccaac
    16561 caataccacc aacaactgca ccatcatcac gaaaagaacg gtcaccatgt aattggataa
    16621 attcatcaaa aatgcctgtc gcaaagtcca aggttgtcaa gcgactctgc tcacgcgctt
    16681 ctctgactat ttttgcaata ttcatctagg actccctcca tgcaatctga ctaggctagc
    16741 aatcgtatct ggtaagtctc ttcttttgac aatagcatcc acaaagccat gttctaatag
    16801 gaattctgcc ttttggaaat cctcaggcaa gctttcacga accgtatttt caatcacacg
    16861 acgcccagca aaaccaacca agctctgtgg ttcagccaga atgatatcgc cttccatagc
    16921 gaaagaagct gtcacaccac cagtcgttgg atctgtcaaa atggtcaggt aaaagagacc
    16981 agcatttgaa tggcgtttaa ccgctgcaga gatcttagcc atctgcatga gactcatgat
    17041 tccttcctgc atacgggctc caccagaggc tgtgaatagg acaactggca atttttcgac
    17101 agtcgcatac tcaaacaaac gagtgatttt ttcacctaca accgtaccca tagaagccat
    17161 gataaaatta gaatccataa tcccaagagc cacagtctga cctttaataa gagcagttcc
    17221 tgtcacaacg gcttcatgca gacctgtttt ttcacgcata gatgccagtt tcttttggta
    17281 accagggaaa tgcaagggat ccttgctttc aatccctgta aacaattctt tgaaggttcc
    17341 catatcaatc gtcaaagcca agcgttcttg ggcagaaata cgaaaggtat agctacagtg
    17401 cggacagata cgttcacttc ccagatcctt ctgatagatg gtatgcttac agcctggaca
    17461 ctgggaaaat aattcatctg gaacctctgg cttagcttga ggtttttccc taaccgaacg
    17521 attgggattg attcgaatat acttatcttt tttactaaat agagccattg attccccttt
    17581 tcggtttaaa ctcttaaagt cattttattc tttttcttga tatttaggta agaaggtttc
    17641 catcaagaag gaagtatcat aatccccagc aatgacattg cgatctgaaa tgagatcaag
    17701 ctggaaatct gcattggtct gcactccttc aatctctaat tcatagaggg cacgttgcat
    17761 tttcatcaag gcgtcaaaac gattttcgcc gtgtactatg attttggcaa tcatactatc
    17821 ataataaggc ggaatggtat aacctggata aactgctgaa tccacgcgca agccaactcc
    17881 accacttggc agatagagat tagtaatctt acctggactt ggagcaaagt taaaggctgg
    17941 gttttctgca ttgatacgac actcgatggc atgaccgcgt aggacaatat cttcttgctt
    18001 aacagacaaa ggctgacctg ccgcaatgca aatctgttcc ttaacgatat caacacctga
    18061 aacaaactct gttactggat gttctacctg aacacgagta ttcatctcca tgaaatagaa
    18121 atttctactt gcttcatcaa gaagaaattc aatggttcct gcattctcat agccaacaaa
    18181 ctctgccgct cgaacagcag cagcacctat ttcatgacgc agcgtttttc cgattgcaat
    18241 cgagggactt tcttccaaaa ccttttggtt attcctttga agagaacaat cccgttcacc
    18301 caagtgaatc acatgtccat gctcatcacc taggatttga acctcaatgt gccgagctgg
    18361 atagataacc cgttctatgt acatggcacc attgccataa ttggccttgg cctcactaga
    18421 ggcagtttca aaggcagaaa cgaggtcatc tggtttttca accttacgaa tccctttacc
    18481 acctccacct gctgaagcct tgagcataac aggatagcca attttttcag caacaatcaa
    18541 agcttcttca gagttatgca cttctccatc tgaacctggt ataacaggca cacctgcttt
    18601 aatcatctga gcacgcgcat tgatcttatc ccccatcata tccataacat gaccagatgg
    18661 accgataaac ttgataccta cttcttcaca catggtcgca aatttggaat tttcactgag
    18721 aaatccaaaa ccagggtgaa tagcttctgc ctcagtcaag actgcagctg atagaactgc
    18781 attaatattg agataagact ctgttgcctt gccaggacca atacaaactg cttcatctgc
    18841 caaaagcgta tgaagagctt ccttatcagc agttgaataa accgctaccg tcgcaatccc
    18901 caattcacgt gccgcacgga taatacgaac cgcaatttca ccacgattgg caattaaaat
    18961 ttttcgaaac atggagaacc tccttagttc ccaattgcaa aagtaaggat accactggct
    19021 gcaagcttgc catccacttc agcctttgct tcaaccacag ctatggtgcc acgacgtttt
    19081 acaaaagtcg ctgtcataac caattggtcg cctggtacaa cttgcttctt gaacttaacc
    19141 ttgtccatac cagcgtaaaa gaccagtttt cctttatttt caggttttga taactccaac
    19201 acaccagcag tttgcgccaa ggcttccata atcagaacac ctggcataac tgggtattga
    19261 ggaaagtggc cgttaaagaa aggttcgtta atggtcacat ttttgatagc aacaatggta
    19321 tcctcgctca cttccaagac acggtccact agaagcatag gataacggtg gggaatagct
    19381 tctttgattc cttgaatatc gatcatttga tacgtaccaa tcctttacca aactcaacca
    19441 tttcttcgtt agagacgaga atttccgtta ccacaccatc cttaggagct gggatttcat
    19501 tcatgacttt catggcttcg ataattacca atgtttgacc ttttttgaca ctatcaccaa
    19561 ctgtaacgaa ggcaggttta tctggtccag cagccaagta aaccactcca acaagtggac
    19621 tctctacaag atttccctca gtagccacac ttgcttcagc tggagctgga acttcttctg
    19681 ctacagtctc tgctggagca gatgtaggag ctactggact cggtgttgct agaacgggtg
    19741 ctggagcgac ttgagttgca acttcaggca caggtcttgc ttcattcttg ctaaactgca
    19801 actcatccgt cccattttta taagaaaatt ctctcaaact tgactggtca aattgagtca
    19861 tcaagtcttt aatatcgttt aaattcatac ttatctattc tcccaacgtt tgaaagcaag
    19921 aactgcattg tggcctccaa aaccaaaagt atttgaaata gcgtatggaa tttctttctc
    19981 caaaccttgt ccataaacga cattagcttc gatataatct gatacttcac ttgtcccagc
    20041 tgtcattggt acaaagttat gacgcatagc ttcgatggtg acgatagctt ctactgcacc
    20101 cgcagccccc agcaaatgtc ctgtaaaaga cttggttgat gatacaggta cttccttacc
    20161 aagaacagct acgatagcac cactttctcc tttttcattg gcaggagttg acgttccgtg
    20221 agcattaaca taggctactt gctctggaga aatctcagct tcttccaagg ctagtttgat
    20281 ggccttgata gctccctgac cttctggatg tggagaagtc atgtggtagg catcacaagt
    20341 atttccgtaa ccaaccactt cagccaggat agtagctcca cgtttttcag cgtgttcaag
    20401 actttctaga accaacatcc ctgaaccttc acccataaca aacccattgc gatccttatc
    20461 aaatgggatc gaagcacgag ttggatcctc tgtagtagag agagctgtta aggcttggaa
    20521 accagcgatg gcaaaaggtg tgatagaagc ttctgttcct cccaccaaca tcacatcttg
    20581 gaaaccaaac ttaatggagc ggaaggcatc cccaatcgca tcatttgatg aagagcaggc
    20641 agtattgata gatttacaaa caccgtttgc accaaaacgc atggctacat tcccagaagc
    20701 catatttggt aaagcttttg gaagagtcat tggtttgaca cgtttgggtc ctttttcatg
    20761 aaggcgaagt acctgatctt caatttcctt gattccacca ataccagatg caacgataac
    20821 accaaaacga tccctattaa gagcctctac atcaagattg gcatggttta cagcctcttg
    20881 ggctgcatac aaggcatata aagaatagtt atcaaaacgg ttggtatctt tttttacaaa
    20941 gtatttatcg aacggaaaat cttggatttc tgccgcatta tgcacatcaa agtcactatg
    21001 atcaaatttt gtaatgccac caatgccgat tttcccagtt gctaaactat tccaaaattc
    21061 ttctggtgta tttccgattg gagatgttac tccataacct gttaccacta ctcgatttag
    21121 tttcattctt ttcacctcta gctttcgcta catacttaag ccaccatcaa tggcaatcac
    21181 ttgaccagtt agataatctt ggcctgctaa aaatactgtc aaatctgcaa cctgctctgc
    21241 ctgcccaaat tctttcatcg gaatctgagc tagtgtagct tccttaatct tatctgataa
    21301 gatagctgtc atatcagact caatcattcc tggagcaatc acattgactc gtatattccg
    21361 actagcgacc tcgcgtgcca cagacttggt aaagccaatc aagccagcct tagaagcagc
    21421 atagttagct tgaccaatat tccccatcaa accaacaaca ctagacatat taatgatagc
    21481 accttctctg gctttcatca tcggtttcaa gactgattgt gtcatattaa aggcaccagt
    21541 cagattgacc ttgagcactt tttcaaaatc tgcttctgtc atcttgagca taagagtatc
    21601 ttgggtaatc cctgcattgt tgaccaaaac atctactgaa cccagttctg caatagcttg
    21661 atcaatcata cgcttagcgt ctgcaaaatc tgatacatct cctgaaatgg gaaccacctt
    21721 gataccatag tttgaaaact cagcgagcaa ttcttctgag attgccccac gactgtttaa
    21781 gacaatgttg gctcctgctt gagcaaactt gtgggcgatg gcaagaccaa ttccacgact
    21841 cgaacctgta ataaagatat ttttatgttc tagtttcatt tttttccttt caaaacttct
    21901 acttatttta gtctattttt ttaaaagtgc tactaaactc gcttgatctt ccacatgagc
    21961 taagtgagta gtttgatcaa tttttttaac aaaacctgac aagactttcc ccggtccaat
    22021 ctcgataaag ttgcttatgc ctgcttcttg catgacccca atactttcat agaaacgaac
    22081 gggttccttg acctgacgcg tcaagagctg agcaatgtcc tctttttgca tcacagcagc
    22141 ttctgtattg ccgactaggg gacaagtaaa atctgaaaaa cttacctgag ccagagtttc
    22201 agctagtttc tggctagcag gttcaaggag agaggtgtga aagggacctg acaccttaag
    22261 aggaatcaag cgtttggcac ctgcttcttg caaaagttca accgctcgat caactgcaac
    22321 cacttctcca gcaatgacga tttgtgcagg tgtgttatag ttggctggag taaccactcc
    22381 aagttcagaa gctttttgac aggcttcttc aatgacctct actggcgtat tgagaactgc
    22441 taccatcttg ccagagtcag caggagccgc ttcttccata taggctccac gcttagctac
    22501 caaggcaacc gcatcttcaa aatccaaggc gccgcttgcc accaaggcag agtattctcc
    22561 aagagacaaa ccagcaacca tatcaggctg atagcccttt tcttgcaata aacggtagat
    22621 agcaaccgaa gtcgctagaa tggctggttg cgtatagcgg gtctgattga gtttgtcttc
    22681 ttccgtatcg atgagataac gcaaatcata acctagcacc tgactcgctc gatcaatcgt
    22741 ttctttaaca atcggatact gatcatagaa atcccgtccc atccctagat actgggcacc
    22801 ttgaccagca aataaaaagg ctgttttagt catttcttac aactcctgtc cagcgagagg
    22861 cttcttcttg aattttctta gcggctccgt aatacaaatc ttttaggatt tcttcagctg
    22921 tttcttcttt agaaacaagc cctgcgattt gacctgccat gacagagcca ccctccacat
    22981 caccgtgaac aactgctttg gctagggcac ctgctcccat ttgttcaaag atttctaaat
    23041 caggatcttc ctgcttaaag gcatcttttt cagccagttc aaaatctcta gtcaactgat
    23101 ttttaatagc acgaacagca tgaccaaagt gctgagctga aatcgtagtg tcaatatccc
    23161 ttgcttttaa aattttctcc ttgtagtttg gatgggcatt cgactctttt gcaactacaa
    23221 accgtgtccc cacctgtaca gcctctgcac ctagcataaa gccagccgca gcaccttcac
    23281 catccgcaat tcctcctgca gcaataacag gaatagatac agctgtggct acctgtcgca
    23341 ccaaggtcat ggttgttaat ttaccgatat gccccccagc ttccattcct tctgcaataa
    23401 cagcgtctgc accgattttt tccatgcgtt tagctaaagc gacactagga acgacaggaa
    23461 taacgattat cccagcttca tggaaacgtt ccatatactt gcttggattt cctgctcctg
    23521 ttgtgacaac tttaacacct tcttcaataa cgagatccac gatatcttcc acaaagggag
    23581 ataagagcat gatgttgacc ccaaagggtt tatcagtcaa tgatttgatt ttatcaatat
    23641 tggccttgac aacttctttc ggggcatttc ccccaccgat aattcctaat cctccagcct
    23701 tggaaacagc ccctgccaaa tcaccatcag caacccaggc catccctcct tggaaaatag
    23761 gatagtcaat cttcaataat tctgtaatac gcgttttcat agtgcctcca accttccttg
    23821 cttacgtaat agttcgattt caccataatt tgacagtcaa actattacct aaacaagagg
    23881 gagtgggttt ctccctactc cttctactaa tattctgctt attttgcttg ctcttcaacg
    23941 taagcaacca agtcaccaac tgttttcaag tcattttctg cttcgatttg gatatcaaaa
    24001 gcatcttcga tttctgagat tacttggaac aagtccaatg aatctgcgtc caaatcatca
    24061 aaagttgatt caagtgttac ttctgatgcg tcttttccaa gttcttcaac gataatttct
    24121 tgtacttttt caaatactgc catgatagga ctcctttaaa ataaatagtt tttttataac
    24181 aatgtgttca ccacatgatt acctaaattg taagaatgag cgtgccccag gtcaaacctc
    24241 caccgaagcc tgatagaaga acagtctggc taccatctaa agggatgaga ccttgttcta
    24301 cacactctga aagtaaaatc gggatactgg ctgcactggt attgccatat tccatcatat
    24361 tggctggaag tttggctcgg tcaacaccaa tttttctagc catcttatcc aaaatacggt
    24421 cattggcttg atgaagtagc agataatcca agtctgtcac ctctatagga gattcatcaa
    24481 tagtctgctt gatagacttg gctacatctc gaatggcaaa atcaaagact gtgcgtccat
    24541 ccatcttcaa aaacgaatct gcactttctt gatctgaaaa tggagaatgc aaacctgaat
    24601 gcccataagt taaacactcg ctgcgacttc catcgctatt gagactctca gctaagaaat
    24661 gctcttgctc gctagcttct aacaagacac caccagcacc atctccaaac aacacagctg
    24721 ttgatcgatc cgaccaatcg actgccttag agagggtttc actaccaatc accaagcctt
    24781 tttgaaagcg accagaagcg ataaactttt cagcagttga aagagcaaat acaaatccac
    24841 tgcaagccgc ggttaagtca aaagcaaagg ctttattagc accaatatta gcttgaacac
    24901 gagcagctgt agagggcatc atcgaatctg gagtaatggt agctaggatg ataaaatcca
    24961 gttcttctcc tgttattcca gcttttgcca tcagtttctt agcaacctct gtagccaaat
    25021 cactggtaga ttctgttctt gaaatatgcc tttgtcgtat tcccgttcga cttgaaatcc
    25081 actcatcatt ggtatccata atctgagcca agtcgtgatt tgtaaccact tgctctggca
    25141 cataatgagc aacctgactt atttttgcaa aagccattat ttcaaatcct ccaaaaattg
    25201 gtaaagatta gtcaagcctt tacccatgac agcaatttct tcctcgctca tgccatcaat
    25261 aattttttct accatggcct tgtggaagcg tttatgcagt ctatgaatca agcgaccctt
    25321 ctttgtcaaa tgcagatgca ccacacgacg atcctgttct gaccgaactc gctcaatgta
    25381 gcccttacgc tctaaattgt tcaaacttgt cgtaacagtt ccaagagtta ccattaactc
    25441 ttttgacact tgacttggag tcacatctgg agccttaccg atgacatcaa ttgtatgcat
    25501 ttctttgatg gagatatcct taaaacgact acctctcaag ttcacttcct caattacaag
    25561 gacattgtta aatatagatg ttaaatattc attgattcgt tggtagtcca tttttcatat
    25621 ccctccttct tcaaaaaact tttacaatca aaacatttga cagaaagaat tatatcaaaa
    25681 ttcaaagaat gatgcaagta ttttttattt tcctgtaaat ttaggtcttc ttctctccga
    25741 atgagctcgc actccttctt tgaaatcctc tgtttgagct aaggatttct gtaggttcag
    25801 ttctaaagta gcgtaaccct gccagtcttt aaattggctc tcccaaacca acttcttaat
    25861 ggcagcatag gaattacttg aagcacgtct taatttttta agaagctgtt ctctcgtctt
    25921 ttcaagtttt tcagcttcag aaacgcggta aaccaacccc cattctaggg ctttttctgc
    25981 cgttaaagcc tctcctgtca tagctaattg agcagcacgc gtcacaccga tactgcggct
    26041 caagagatga attccccctg catctggagc caaaccaaca ccaacaaagg cttggataaa
    26101 cttagcctta tccgtcgcca aacagaaatc tgccgcaaca gccatattcg ctgcggcacc
    26161 tgcaacagca ccgtcaactt ccattaaaac aggtttggct atttgcttga ttttataaga
    26221 aatcgtattg accaactctg cgatttttgt caatgatgga atatcatcct catccactgc
    26281 ccgcttcatc tctaccaaat ctcccccaac tgagaagacc tttccattgg cattgattaa
    26341 gataaaatgc acagctggat tttcttctgc caaagtcaga gcttctaaaa tctcctcaca
    26401 catgggaata tgaaaaccat ttgcgacctc aggacggttc aaggtaagga ttgccaagtc
    26461 ctcttcaagc tgataaataa tgtgttccat cagggctcct ttttatttta taagcagttt
    26521 atactcttcg aaaatctctt caaaccgcgt cagcttccat ctgcaacctc aaaacagtat
    26581 tttgagctga cttcgtcagt cttatttaca acctcaaagc agtgctttga gcagtctgcg
    26641 gctagcttcc tagtttgctc tttgatttca ttgagtgtta aattatttca ctgtcaaagt
    26701 atatcttttt taggagcaga aagcaagaaa aaatcgactg aaagtgtctc agccgataag
    26761 aaaggctcgc tttaggctag aaagcatctt attttcttca ttgaaaaaag cctttctttc
    26821 tgctataatc gtataaaata cttactttag gagttcttat gaaagttgtt aaatttggag
    26881 gtagttctct tgcctctgct agtcaattag aaaaagtttt aaacatcgtc aaaagcgatt
    26941 cagagcgtcg ttttgtagtc gtttctgcgc ctggtaaacg caatgctgaa gatactaagg
    27001 ttacggatgc cctgattaaa tactaccgcg actatgttgc gggtaacgat attagcaaga
    27061 gccaaagctg gattatcgac cgctatgctg ctatggttag tgaattggga ctaaaaccag
    27121 ctgtgctaga aaaaatttct aaaagcattc acgccttggc cactcttcct attgaagaaa
    27181 atgaatttct ctacgatact ttcctagcag ccggtgaaaa taacaatgcc aaattgattg
    27241 ctgcctactt taaccaaaat ggtatcgatg cacgctatat gcaccctaga gaagctggga
    27301 ttgtggtcac aagtgaacct ggtcacgctc gcatcattcc atcaagttat gacaagattg
    27361 aagaattgac aaacaccaat gaagtccttg tcattcctgg tttctttggt gtcactaagg
    27421 aaaatcaaat ctgtactttc tcacgtggag gttctgatat tacaggttct atcattgctg
    27481 ctggtgtcaa agccgacctc tatgaaaact ttacggacgt tgatggtatc tttgcagccc
    27541 accctggtat tatccaccaa ccacactcga ttcctgagtt gacctaccgt gaaatgcgcg
    27601 agttggccta tgcaggcttc tcagtccttc atgacgaggc tcttcttcct gcctaccgtg
    27661 gaaaaattcc tctggttatc aagaatacca acaaccctga ccatccaggt actcgtatcg
    27721 ttctaaaaca cagtaatgat gaatttccag ttgtgggaat tgctggtgac tcaggctttg
    27781 tcagcattaa catgtcgaaa tacctcatga accgtgaggt tggatttggc cgcaaggttc
    27841 tgcaaatcct ggaagaactt aacatcggtt gggaacatat gccaacaggt atcgacgatc
    27901 tttctatcat tctccgttct cgccaactaa ctcccatcaa ggaagaagaa atcctgcgtc
    27961 agttggttca aaaggctaaa gtagatcatg cagaaatcga acacgacctt tctatcatta
    28021 tgattgttgg tgaaaaaatg aagagccaca tcggagtgac tgctactgcg acacgcgctc
    28081 tatctgaaaa caaaatcaac atccagatga tgtctcaagg ttctagtgaa gtttctatta
    28141 tgtttgttgt caataaagac caagagaaag cagcaattaa agccctctac aatgcctttt
    28201 ttggagaaag taaggaagac taagcatggc ccaatcactt aacaaaacag tactcctcag
    28261 tacgacaggc acttcctacc tctctatcgc tgggaaagtt gggaaattcc ttgtcggaga
    28321 tcaggctttg gaattttacc cagatgtcaa tgtcgaacaa tttatccaga ttccttggag
    28381 ccatatcaat cagattggag ccaatgtcac tggacgcaaa atcagccgcc acttcgaagt
    28441 ctttacagac aaaggaaaat tcctctttgc ttcaaaagac tcaggtgcca ttctcaaaat
    28501 tgcacgcgaa aaactaggca atgacaaggt cgtcaaactt ccgaccctga ttcagacaat
    28561 tagccaaaaa tttaaaaatc tatttgcaaa aaagtagaaa ctttagtata atcatagcaa
    28621 cggataagta ggttatcttc ttctttcaga aagtctgcgg gtactgcgag cagatagggg
    28681 ggataggtga aattctaccg ttagtaacaa ttacatacac aatcaagtgc acacctgtga
    28741 agttggatgg aaccgtggcc ctgccactcc aacgttttgt caggcgtgct tttttcataa
    28801 aggagttctt atgttagata tcaaacgtat tcgtacagat tttgaagctg tcgcagaaaa
    28861 attagctaca cgtggtgtag aggctgctgt cttgaatgaa atgaaagaaa tcgatgctaa
    28921 acgtcgtaac atcttggtca aggttgaaac tctcaaagca gaacgtaaca cagtttctgc
    28981 tgagattgcc caagctaagc gcaacaagga aaatacagat gacaagattg ctgccatgca
    29041 aaatctatct gctgaggtta aagccttgga tgctgaattg gcagaaatcg atgctaaatt
    29101 gacagaattt acaacgactc ttccaaatat cccagctgac agcgttcctg ttgggactga
    29161 cgaagacgac aatgtggaag ttcgccgttg gggtactcca cgcgagtttg acttcgaacc
    29221 taaagctcac tgggatctcg gtgaagacct tggtatcctt gactgggaac gcggtggtaa
    29281 ggtaacaggc gctcgcttcc tcttctataa aggcctcggt gctcgtttgg aacgtgctat
    29341 ctacaacttt atgttggatg aacatggaaa agaaggctat actgaagtca tcacacctta
    29401 catagtcaac catgattcta tgtttggtac tggtcagtat ccaaaattta aggaagatac
    29461 ttttgaactc agcgatacca actttgtctt gattccaact gctgaagttc ctctgacaaa
    29521 ctactaccgt gatgaaatct tagacggcaa agatcttcca atctacttca ctgccatgag
    29581 tccgtcattc cgttctgagg ctggttctgc cggtcgtgat acgcgtggct tgatccgttt
    29641 gcaccaattc cacaaggttg aaatggtcaa atttgccaaa ccagaagaat cttacgaaga
    29701 attggaaaaa atgacagcca acgctgaaaa cattcttcaa aaactcaacc ttccataccg
    29761 tgtcgttgct ctctctactg gagatatggg cttctcagct gcgaagactt acgacttgga
    29821 agtgtggatt ccagcacaaa acaattaccg tgaaatctca agctgttcaa acacagaaga
    29881 tttccaagcc cgtcgtgccc aaatccgtta ccgtgatgaa gcagatggca aggtgaaact
    29941 ccttcatacc ttgaacggtt ctggacttgc agttggacgt acagtggctg caattcttga
    30001 aaattaccaa aatgaagatg gttctgtgac catcccagaa gcacttcgtc catacatggg
    30061 tggagctgaa gtcatcaaac cataaaaaat aaggtttagc tatttctagc tagacctttt
    30121 ttcgtaacca aatcagataa gcacctagta caaagaataa aatagttagg catataatgg
    30181 tttcagccaa taccaggtaa tccagaaatg gaagtttcaa aattccctga gccatcttga
    30241 gcgaggtcgc tgtgataatg gttgggaagg tgagggctga gaaggctggt tgaaaacctt
    30301 gttttaaaat gttgggcaga cgagttaaaa caaagaaaaa gaaggattga gaagccaaaa
    30361 tcatgacaat caagacccaa gtcggcaggc tggttcctcc tactcgaact agagaagcca
    30421 agagtagaga gaaaggagca cagtagattc cttcttgtcc aagcaaggct agtgggagtg
    30481 gatgtttctt taaatcgcta taaataaggg gatagagata gaaggtcaag agaaaaccaa
    30541 aactcaaggt cgcataggca atttcgataa tacctaccag aggataggtc aaggcagcca
    30601 ctgctatccc cacatagaga accgtccaac ttggagtggc atgaaccctc cgccctgaac
    30661 aagcaaactt gatggtaaaa ccagcaatca aggtcaaatc caagagaaat gaaaaccacc
    30721 aaatcccttg tgctaccaaa ggaagataag agaatacgcg aaagacatag gtcgataaaa
    30781 tcatcccagc cataggaaag gttgccattc ctgacaaaag agggggcttg gtcaattctt
    30841 gcttggtttc tttccaatta aagagatgca gaattagaaa gtaaatccat aaaaccaaac
    30901 cagtcagact aaaaagatgg gatagaaccg gcaacgtatc taaaataaga tttccagctc
    30961 ctgccaaacc tagcaaacaa cctgaaaata ctaaggggag ttttttcatc ctaacctcca
    31021 ataatcatgt tagtttcagt ataacataaa agcgcttaaa tgaggattta aaaaaacgaa
    31081 gtccgcttat ttcagacttc attttactca gatatgaatt aggcataagg ttgcaattct
    31141 ggattaattg gtgtattagc taagttgttg gcatagttac agaggattgc taggctgaca
    31201 ccaaaaacca catccaaggc attttgttga gtgtagccag cttctaaaaa ctcagacaag
    31261 gcttcatctc ctacacgacc cttggtattg ataactgcca aggtaaactt agctagggta
    31321 tccaatttag gatctgtttc aattggagta cgattgcgaa gagcttgaat caagtcatca
    31381 ttcatctgga tttgtttgat ggaaaaggct gtgtgacctg cgacacagaa ggcacaacca
    31441 ttggtcacgg ctgccgtgat ttgcaccact tcacgctcaa cgggtgtcag gctgttgcga
    31501 cggtggatag atgagacaat ttggtaggct tctaaaacag tcggggcatt ggccaagaga
    31561 ccgattaggt tgggaatata gccattgttg tctttttcta ctgtttcaag aatttctttc
    31621 acttctgctg gtgctgactc tactgtatgg atagtaaatg ttgtcataag atacctcttt
    31681 tcttattatt gacactaata ttattggaaa atcttataaa atcctgattc ctaagtttat
    31741 ctaagataaa gctttattct ctcataagat tttcgttgtt atattagttt atcacacttc
    31801 caatcacttg cataatatat attatatatc aggctgataa aaattattta taggcaaaaa
    31861 aatcacacga gctgtgtgat tccattattt gtcaaaatac tttttagttt cagcaataac
    31921 gactggcgac aagaccaaga gggcaatcaa gtttggcaga gccatcaagg cgttaacgat
    31981 atctgcgata atccagacca tatccaactc gataaatcct cctaacaaga ccatgagcac
    32041 aaaaaacaca cggtagagcc agataaagcg agccccaaag aggaactcaa aacagcgttc
    32101 tccgtaatag ttccaaccta gaatcgttgt aaaggtaaaa agtacaagga agatggtcaa
    32161 gagggcaggc ccaaagtgtg aaaagactgt tgagaaagct gactgagtca aggcaacccc
    32221 attcaagtca ccactccaaa ctccagttac caagatggtc aaaccagtta gagtacaaat
    32281 gatgagggta tcaataaagg ttcctgtcat ggaaatcaaa ccttgctcta ctggttcatt
    32341 tgtcttggca gctgcagctg caataggagc agaacccaga ccagattcgt ttgagaacac
    32401 accacgcgcc acaccatttt gaatagccat ccgaacgcta gcaccagcaa atccacctac
    32461 cgcagcaagg ggactaaaag ctgaggtaaa gactaaagcg attgtgccag ggatttttcc
    32521 gatattaaag aaaataactg taagagttcc taagatataa atgagggcca taaaaggaac
    32581 aacagtagtt gaaaccttag aaatagactt gagtccacca aagactgcaa tcgctacaaa
    32641 gacagacaag acgagagctg tgatggctgg cgaaatcgtc gttgtatttt ggatagattc
    32701 tgtaatcgag ttgacttggg tgaaggttcc gattcccaag agagcaacca atactcctgc
    32761 tactgcaaac aaaacagcaa gtggtcgcca cttttctccc atccctagaa ggatatagtg
    32821 catgggacct cccgctactg caccatggtc gtccttggtg cggtatttga tggccaagag
    32881 tccttccgca tacttggtag ccattccaaa gaaagccgcc atccacatcc aaaatagagc
    32941 tcctggtcca ccaaccttga tagccgtcgc aactcctatg atatttcctg ttccaacagt
    33001 tgatgccaag gctgtacaca gagctgcaaa actggataca tcaccatgtc ccttatcctg
    33061 gataaaaata agctgaaagg ccttgggcag acgcaaaacc tgcaagagtc ctagccgcat
    33121 ggttaggtaa atccctgttc cgaccaataa aatcaagagg ggcggtcccc aagcaaaagc
    33181 atcgattgat ttaagcaatt ctaacatttt cttctcctat cgtttcaacc ccaaaagaaa
    33241 gagcacatgc aagatacatg tactctggaa tgcttagata aatgctaaaa agcggtctat
    33301 cctagctctg tccttttacc tgagagtttg agcagttgcc tgccttgccc cttcggtgcc
    33361 tttacggtct ctccagagtt ccgtccattt acagtcatgg aaaatcaaac gattccccac
    33421 ttctattaaa cttcattcgg tgttggtatt taattgattc taattttaca aaaaatgttg
    33481 gcttttgtca atgtgtttat tagtaaaaat tagttcaaca gtttttactt tataaagtcc
    33541 agaatactgc tatcctttaa aagtgacaat agtcgcacca ctgcctccag cattttgtgg
    33601 ggcatagccg aaactcttga catgtttgtt tctttgcaag tatttggtaa ctccttcacg
    33661 gatgactcct gttccgatac catggatgat atcaacttga gccatattgt taagcaaggc
    33721 ttggtcgatg aaggtatcta gctcattcat ggcttcttca tagcgcttgc ctcgaagatc
    33781 cagtctagct tgaggtcctc gcccagaagt tcgtttcaca acattgacct gtttcttctt
    33841 gactggtttt tcttgctggg cttgaacaag atcaaactct ttctcttcca aggtcatctt
    33901 aatcaagcca atttgggctt cccagcggcc gtccttgagt tgactggtca aggtaccacg
    33961 ctgaccataa ctgagaacca cgatatcatc tcccaccttt ggagctcgtt ttttcttggc
    34021 cttttgaagg accttgtttt tagacaagtc cactttttca ggagccaatt ttttcaactt
    34081 ggccttggct tcaatgattt cgtggggctt gagttgggat ttactgtgga gatttttgag
    34141 aatctggtca ctttcactta gggccatatc cacaatctca gcagcctgtt cacgcgcctt
    34201 gttaagctcg gtttcctttt cacgattaag ctcgttgtag agttttttta gcgcacggtt
    34261 catcttgaga ttttcttgct ccacctcacg gatattgtcc aagcgtttgc ggctttccag
    34321 cgtctgctct tctaattgct caatgatacg attgacgtca ttgtcctgat cgatctgctg
    34381 actggcatct cctacgataa cttcagatag gcctagacgt ttggcaattt caaaggcatt
    34441 acttcggcca ggaacaccct gcataaagcg ataggtcggg cgaagagttg cagtatcaaa
    34501 ctccatactg gcattttgca caaaggctgt ctcaataccg taggccttga gttctggata
    34561 gtgggtcgtc gccatggtct tgatttgacg caggcgaagg tcctccagaa tagccatggc
    34621 aagggctgct ccctcttggg gatcagtacc agcccccaac tcatccaaaa gtaagagtga
    34681 atgttggttg accttgccaa gaatatccac gatattggtc atatggctag agaaggtaga
    34741 caagctctgc tcaatagact gctcatctcc aatatcagca aagatttctt caaaaatacc
    34801 aacacgactt cccttgtctg ctaaaatcgg caatcctgac tgggccatga cctgtgtcaa
    34861 gcccagagtt ttaagcatga tggtcttccc acctgtattg ggacctgtaa tgacaatagc
    34921 tgttaaatct tgaccaaaat agacatcatt tgcgacggca tttttgacca aaggatggca
    34981 gacatggagc agttgaatct cttgattttc tgacagctga ggcacgactg cttgtctttc
    35041 ttgaataaat cgaaccttgg cacgaatcaa gtccagatga ccgataatcc aagcgtcatt
    35101 agcaatctca gccgcatgag ggcggacacg ctcagaaatt tcttggagaa tgcgaagcat
    35161 ttcatagcgc tcatctgctc gcagactagc aatttcttcg ctcagtttga ctacctcacg
    35221 tggttcgata tagacggtgt ttccactagc agaaatatca tgaacgacac ctgcaatctt
    35281 attgcggtag gtgtttttga ctggtaaaac ctgacggcca tttctgctag caacaattcc
    35341 ttccgtcaac atctgccctt tttgcttgag caagtcttgt aaaacatcgc gtacctgact
    35401 ctcgctatca tgtatttttc gacggattcg cgccaattct tcactggcaa aattttcaat
    35461 gaaacccgca tcattaaagg cctgaagatt tccttgtaat tgcggaaaat catgtaattt
    35521 ctcaaaccaa agggctaatt cttccaagct gacattttcc agattggcgt aaaaactttg
    35581 aagttctcgg ctggcaagaa gcacgcgttt caagagtagg aactcctcga tattgagatc
    35641 cgctcccatc tccaacctct tgcagactcc tgcaatttcc ttagttgaga gaatagtaaa
    35701 atgcggttgc tcgacgaaaa gagcctgcat ttctttcatc tcagcaaaag cctgtttgat
    35761 tttatctgct ttggcagtcg gagccagctg tctcaattgc tccaagccct gctcggtcaa
    35821 caaatgaggc tcaaacaagg ccttgacctt atcgaactct aatgtttcta atattttctt
    35881 attcatcttt atttccttgt ctttgaatgt ctaggtgtgg tagcttttta cattctgata
    35941 gattcgagtc aaatctgtaa acaaagggct aggaaaactc ctgccctttt tatccgatta
    36001 aatttgtcac ccagatttgt ttgagccaac tggttgttat cggtatgctc tggatgatgt
    36061 gttttgcgac gatactcttt tcaagaggat tttgtataac tgccataggg atggtcgcca
    36121 agattgtcaa ggccatttgc aagacaaata aggtcaccaa catggacaag atacctgctg
    36181 aaacttggaa caacttacca cccagttttt tgctaggaat caagtgtaag agaagaccaa
    36241 gcaaacgacc aatgctatag acaatcccaa atacaagcaa gtagccgata cctgcataaa
    36301 agaccttatc cagctgaaag agttgatccg atgggaaaaa gaaagtcccc tgaccttcct
    36361 gcgaatttgc ataagggagc aataaatgga attgctctcc aagcccctta taaaactggc
    36421 cagccataaa agccgatgcc atggctgaaa tcaggtaata aacctgtaag agcaggcctc
    36481 tccgatagcc gatataaaat ccccaaacca agaccaatag aagaaggaat gaaatcataa
    36541 ggaatcctca atcttgctct gttcttgctt acaagtcaca agcttgtgac ggagttcttc
    36601 tagctcttgc tccttatcgt caaattcaat ctcacggctg agctgagttg ataaacagtt
    36661 gactgccaac aaaagagcga ttgtttcatc atctgcgcta ggcatttgtt ctttaattgc
    36721 ttggtatttt tctgtcgcaa ccttagcgat ttcctccata aaaaggttat catgttcgct
    36781 tgtcaaggtt aacgtttttt tcccgaatgt aaatttgaat cgatttagat ttgccataaa
    36841 attcacctca cgatattata ccaaaattcg ctaattttgt cagtttttac aaattttact
    36901 gcttttgtgg tacaatagaa actatggcaa gtatcacact cacaccaagc gaaaaggata
    36961 ttcaggcttt tcttgaacac tatcaaacca gtctggctcc tagcaagaat ccctatatcc
    37021 gctacttttt gaaactacct caagcaacgg tttctatcta tacttctgga aaaatcttgc
    37081 ttcagggtga aggggctgaa aaatacgcca gtttctttgg ctatcaagct gtagagcaaa
    37141 ccagcggaca aaatcttcct ttaattggga cagatgaggt gggaaatggt tcctactttg
    37201 gtgggcttgc agttgtggct gcctttgtca cacctgacca gcacgacttt ttacgaaaac
    37261 tcggtgtggg ggattctaag actctgaccg accaaaagat ccgtcagatt gctcctattc
    37321 tcaaggaaaa aattcagcac caggcactcc ttctctcacc cagcaagtac aacgaggtca
    37381 tcggagaccg ctacaatgct gtttcggtta aggttgccct ccataatcag gctatctatc
    37441 tcctccttca aaaaggtgtt cagcctgaga aaattgtgat tgatgccttt accagtgcta
    37501 aaaattatga caagtacttg gcacaagagg ccaatcgttt cagcaatcct atcagcttag
    37561 aagaaaaggc tgagggcaaa tacttggctg tcgcagtttc ttctgtcatt gcgcgtgatc
    37621 tctttctgga aaatcttgaa aatctgggac gagaactggg ttatcagctc ccaagtggag
    37681 ctggaacagc ttctgacaag gtggctagcc agattttgca agcctatggt atgcagggac
    37741 tcagcttctg cgccaaattg cactttaaaa acactgaaaa agcgaaaaaa cgcttagaaa
    37801 ggtaagttat gaattcattt aaaaatttct taaaagagtg gggattgttc ctcctaattc
    37861 tgtcattact agctttaagt cgtatctttt tttggagcaa tgttcgcgta gaaggacatt
    37921 ccatggatcc gaccctagcg gatggcgaaa ttctcttcgt tgtaaaacac cttcctattg
    37981 accgttttga tatcgtggtg gcccatgagg aagatggcaa taaggacatc gtcaagcgcg
    38041 tgattggaat gcctggcgac accattcgtt acgaaaatga taaactctac atcaatgaca
    38101 aagaaacgga cgagccttat ctagcagact atatcaaacg cttcaaggat gacaaactcc
    38161 aaagcactta ctcaggcaag ggctttgaag gaaataaagg aactttcttt agaagtatcg
    38221 ctcaaaaagc ccaagccttc acagttgatg tcaactacaa caccaacttt agctttactg
    38281 ttccagaagg agaatacctt ctcctcggag atgaccgctt ggtttcgagc gacagccgcc
    38341 acgtaggtac cttcaaagca aaagatatca caggggaagc taaattccgc ttctggccaa
    38401 tcacccgtat cggaacattt taagaaacct aagaggccga gaatcaccaa tctcagcctc
    38461 ttcttctatc gtgagaagtg attgtttatt gacaaatact caatgaaaat caaagaacaa
    38521 actaggaagc tagccgtagg ctgcttaaaa cagtgttttg aggttgcaga tggaagctga
    38581 cgtggtttga agatattttc gaagagtata aaataaaaac aatcccaact ctcacctatt
    38641 catgcaaagg aattttatgg aagtttattt ttcaggaacc attgaacgga ttatttttga
    38701 aaatcccagc aatttttatc gcatcctcct cctagaaatc gacgatacgg acgcagagga
    38761 ttttgatgac tttgaaatca ttgtcacagg aaccatggct gatgtaattg agggcgaaga
    38821 ctatactttt tgggggcaaa ttgtccagca ctccaagtat ggagaacaac tgcaaatcag
    38881 tcgttatgat cgcgcaaaac caactagtaa gggcttggtc aagtactttt caagtagcca
    38941 tttcaagggg attggtctca agacagctca gaaaatcgtg gatacctatg gcgaaaatac
    39001 cattgacgaa attttgcaac acccagaaaa gttagaaggc atcgcaggac tctctgccaa
    39061 aaatcgcgag gctttcgtct ccactctccg tctcaactac ggtacggaga tggttttggc
    39121 caaactagcc aactacggca ttcccaacaa actagccttt cagattcaag acttttacaa
    39181 ggaagaaacc cttgatgtgg ttgaaaatta tccctaccaa ctggttgagg atatcaaggg
    39241 tttgggcttt accattgctg accaactagc tgaggaacta ggcatcgaaa gtcaggctcc
    39301 tgaacgcttc cgcgccggtc tagttcacag tctttttcag gcctgtatgg aaacaggaga
    39361 cacctatgtt gaagcacggg atttgctgga acaaaccctt actctccttg agtcttcccg
    39421 tcccgtggaa ctagacccca gccaagttgc ccaagagctc tcctacctga tcgaagaaga
    39481 caaggttcag cagattgata ccaagatctt tgacaacagc ctctttttcg ctgaggaagg
    39541 catccgcagt cacttggttc gtatccttga aaaaggaaaa cagaagagtc atgatttaga
    39601 aaccattcaa aaacatatca ctactatcga ggaagagctg ggaattgagt atgataacat
    39661 tcaaaaacag gctatctgtg acgctatcca gaacaaggtc tttatcctga caggtgggcc
    39721 tggtactggt aagacaactg ttatcaatgg aatcatcgct gtttatgccc ttttagaagg
    39781 acttgacttc aggaagaaaa acaatctgcc cattcttctt gctgctccaa ctggacgagc
    39841 cgctcgccgc atgaatgaat tgacaggttt gcctagcgcg accatacacc gccacttggg
    39901 aatgacaggt gacgatgata ccagtcatct ggaagattac ctagatgctg actttatcat
    39961 cgtggatgaa ttctctatgg tggatacttg gctggccaat caactcttct ccaatatctc
    40021 ttctaacagt aagatcctca tcgtgggtga cagtgatcag ctaccttctg tcagtcctgg
    40081 acaggttcta gcggatctgc ttcatattcc tttgattcct cagactcgct tggaaaaaat
    40141 ttatcgacaa agcgaagaat caaccatcgt caccctagct agtcagattc gacagggcat
    40201 cttgccagct gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa ttgctagtgg
    40261 ccatattcct gccactattg aaaaaatctt aggtgccgcc ctcagaaata gtattcctgc
    40321 ccgtgatatc caagttctgg ctcctatgta ccgagggacg gcagggattg atgctatcaa
    40381 tcagctcatg caagacctgc tcaatccccc acaaaaagat caactcagtt ttgaagctcc
    40441 tcagtgccac tatcgtaagg gagacaaggt cattcatttg gttaacgatg ctgaaatcaa
    40501 tgtctttaat ggggatttag gagctatcac agacctgatt cctggtaaat acaccgaatc
    40561 gaaacaagac gagattgtca ttgattttga tggtaatgaa gtctcttacc cccgtaacga
    40621 atggtacaag attcgcttgg cctatgccat gagtattcat aagtctcagg gaagtgagtt
    40681 cccagttgtc atcctaccga ttactagtgc tagccgacgt atgctggagc gaaatctcat
    40741 ctacacagcc attacacgtg ccaaaagcaa actcatctta ctaggcgaat tacaagcctt
    40801 cgactatgct acccaacaca tcggaactgc ccgaaaaacc tatctgattg aacgcttcag
    40861 tgatctactg gagaatgttg aagaaaagca acaagctgtc tctgaaacag tcacatcaag
    40921 tgcctctgaa caatcctaca tcctaaccga agaaaactgg gacagcattc cagccatgat
    40981 tgggattaca gacacagacc tcaaagagat ttttggaaaa tagtgcatca gaaaaaccac
    41041 caattcaggt gggttttctg tttattaaga ttattttact gttgctgtgc ttgtgatcaa
    41101 ttcaacagct tttttgatag tgatatcatg tttcaacatg tcagctgaaa gcaagttttg
    41161 aacttgtgca acttccatgt tgtagtctgc tgccaattgc tcaacttctt tttggatttc
    41221 ttcttctgaa gcatcaaatc cttcagcttt ggcaactgct tcgataacaa ggttagtctt
    41281 agtacgtgac tcagcttctg cttggtattg gttgtgaagg tcttcttgag tagttccagt
    41341 gatttggaag tacatgtcag ggttgatccc ttgacgttgc aaattcccaa ggaattcatt
    41401 tactgaacgg tgaacttctt catggatcat ttcttctgga agttctacga tttcagcatt
    41461 ttctacagct gtatcaattg ctgcaccttc aactgcatct ttgtaagctt cttctttagc
    41521 agcagccaat tctttgcggt atttttcttt caagtcagca agtgtttcaa cttcttcatc
    41581 aatgtctttt gcaagttcat cgtcaagagc tggaacttct ttagctttta cttcgtggat
    41641 agttgtcacg aatttagctt ctttacctgc aaggtcttct gcttggtagt cttctgggaa
    41701 tgttacgata acatcaacgg tttcgccagc tgagtgacct accaattggt cttcgaaacc
    41761 agggatgaat tgacctgaac caagtccaag tgagaagttt tcaccttttc caccgtcaaa
    41821 ttcaacaccg tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt tttcagcagc
    41881 agcttccttg ataaccaatt cagccaggtt gttgcgttcg cgttcgatac gctcttcgac
    41941 atcagcgtca gttacttctt tttctacatc aactgatact tcaaggtttt tgtagtcacc
    42001 caattttact tcaggttttg taacgacttc agcagtgata acccagtctt gacctttttc
    42061 cattgaagtt acgtcaattt ttggttgggc aaccacttca agaccagctt cttttacagc
    42121 tgcttcataa gcgtttggca aaagagcgtt cataacgtct tggtaaagtg attcttcacc
    42181 aaatttttgg tcgaagatag gacgtggaag gtgaccttta cggaaacctg gaacattaag
    42241 agatttcttc actgacttga agacacggtc caattctggt ttgatttggt cttgagagat
    42301 agtgaaagtc aagacaccac ggtttgtttc tttgttttca aatgatacag acattctgtc
    42361 atttctcctt aaaatttttt aaatacagtc tattataaca ttttctataa ataaaatcta
    42421 gactaatgca gccaattata gacaacaagc ctttttccta actaaaacac tcataaagta
    42481 tagacaattt tagactactt tggatatctt ttggttagtc attttccaaa actaatttat
    42541 ct
//
LOCUS       DAVKBK010000012        42435 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVKBK010000012 DAVKBK010000000
VERSION     DAVKBK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42435
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.012"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..3565
                     /locus_tag="VWX69_000706"
     CDS             <1..3565
                     /locus_tag="VWX69_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9192092.1"
                     /translation="GAQGAKGEKGDQGERGLTGAQGAKGEKGDQGERGLTGAQGAKGE
                     KGDQGEQGLQGRDGEQGPKGEDGKNPTVKVTDGQDGTHTITINDGKGGITTTVVRDGF
                     DGASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDN
                     GKDGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQT
                     TLTFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKD
                     GDTFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGAKG
                     ADGAAGRDGRDGRDGKDVLNGKVNPEANQGKDGDKYVNTETGDVFVKNNGNWDKEGNI
                     KGPKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGKDPVTVNVKDGENGLNGKTP
                     KVDLLRVQGQNGNPPHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGADGRDGKS
                     LLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEAGHKGVE
                     ITVDNHDGSQPTTVFVQDGAKGETGATGQDGQTPTITTQRGQDGQSTVVTITTSGKDP
                     VTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRVTVYDDVNDNGV
                     YDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDGSESTTVVKDGK
                     DGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDGTHTVKV
                     TDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNGRDGVDG
                     RTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKISVLNGDG
                     TTTETIIKDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPTVTVK
                     NNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTVTKT
                     VIKDGKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKP
                     VPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVAP
                     TTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            complement(3802..4350)
                     /locus_tag="VWX69_000707"
     CDS             complement(3802..4350)
                     /locus_tag="VWX69_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9192093.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            4671..5159
                     /locus_tag="VWX69_000708"
     CDS             4671..5159
                     /locus_tag="VWX69_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU9192094.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            5156..6343
                     /locus_tag="VWX69_000709"
     CDS             5156..6343
                     /locus_tag="VWX69_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9192095.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            6336..6701
                     /locus_tag="VWX69_000710"
     CDS             6336..6701
                     /locus_tag="VWX69_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9192096.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            6717..8063
                     /gene="asnS"
                     /locus_tag="VWX69_000711"
     CDS             6717..8063
                     /gene="asnS"
                     /locus_tag="VWX69_000711"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU9192097.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            8216..8506
                     /locus_tag="VWX69_000712"
     CDS             8216..8506
                     /locus_tag="VWX69_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU9192098.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            8518..8988
                     /gene="ssbA"
                     /locus_tag="VWX69_000713"
     CDS             8518..8988
                     /gene="ssbA"
                     /locus_tag="VWX69_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU9192099.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            9020..9259
                     /locus_tag="VWX69_000714"
     CDS             9020..9259
                     /locus_tag="VWX69_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU9192100.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            9554..10954
                     /locus_tag="VWX69_000715"
     CDS             9554..10954
                     /locus_tag="VWX69_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU9192101.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            10956..11315
                     /locus_tag="VWX69_000716"
     CDS             10956..11315
                     /locus_tag="VWX69_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU9192102.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            11369..12118
                     /locus_tag="VWX69_000717"
     CDS             11369..12118
                     /locus_tag="VWX69_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU9192103.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            12108..12407
                     /locus_tag="VWX69_000718"
     CDS             12108..12407
                     /locus_tag="VWX69_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU9192104.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            12478..13413
                     /locus_tag="VWX69_000719"
     CDS             12478..13413
                     /locus_tag="VWX69_000719"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU9192105.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            13499..14011
                     /locus_tag="VWX69_000720"
     CDS             13499..14011
                     /locus_tag="VWX69_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU9192106.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            14036..14644
                     /locus_tag="VWX69_000721"
     CDS             14036..14644
                     /locus_tag="VWX69_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU9192107.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            14745..14942
                     /locus_tag="VWX69_000722"
     CDS             14745..14942
                     /locus_tag="VWX69_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9192108.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(14985..16430)
                     /locus_tag="VWX69_000723"
     CDS             complement(14985..16430)
                     /locus_tag="VWX69_000723"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU9192109.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVKDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            16536..18158
                     /locus_tag="VWX69_000724"
     CDS             16536..18158
                     /locus_tag="VWX69_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9192110.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLCSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            18362..20320
                     /locus_tag="VWX69_000725"
     CDS             18362..20320
                     /locus_tag="VWX69_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9192111.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSVQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            20492..20725
                     /locus_tag="VWX69_000726"
     CDS             20492..20725
                     /locus_tag="VWX69_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEU9192112.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            20731..22173
                     /locus_tag="VWX69_000727"
     CDS             20731..22173
                     /locus_tag="VWX69_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192113.1"
                     /translation="MRKKVIEGLIYAEKSFFDKSQSGELTSAIVNDMSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIYSSSKGSSVA
                     LENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNVVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGRSQRLQIARA
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            22331..23425
                     /locus_tag="VWX69_000728"
     CDS             22331..23425
                     /locus_tag="VWX69_000728"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9192114.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            23433..24599
                     /locus_tag="VWX69_000729"
     CDS             23433..24599
                     /locus_tag="VWX69_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9192115.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            24692..27790
                     /locus_tag="VWX69_000730"
     CDS             24692..27790
                     /locus_tag="VWX69_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9192116.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            27838..28455
                     /locus_tag="VWX69_000731"
     CDS             27838..28455
                     /locus_tag="VWX69_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9192117.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            28466..29800
                     /locus_tag="VWX69_000732"
     CDS             28466..29800
                     /locus_tag="VWX69_000732"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU9192118.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            29810..30274
                     /locus_tag="VWX69_000733"
     CDS             29810..30274
                     /locus_tag="VWX69_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192119.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            30271..30765
                     /locus_tag="VWX69_000734"
     CDS             30271..30765
                     /locus_tag="VWX69_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192120.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            30846..32501
                     /gene="mltG"
                     /locus_tag="VWX69_000735"
     CDS             30846..32501
                     /gene="mltG"
                     /locus_tag="VWX69_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU9192121.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            32572..33054
                     /gene="greA"
                     /locus_tag="VWX69_000736"
     CDS             32572..33054
                     /gene="greA"
                     /locus_tag="VWX69_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU9192122.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            33562..33960
                     /locus_tag="VWX69_000737"
     CDS             33562..33960
                     /locus_tag="VWX69_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192123.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            34405..35412
                     /locus_tag="VWX69_000738"
     CDS             34405..35412
                     /locus_tag="VWX69_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9192124.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            35487..35687
                     /locus_tag="VWX69_000739"
     CDS             35487..35687
                     /locus_tag="VWX69_000739"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU9192125.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            35722..36438
                     /gene="atpB"
                     /locus_tag="VWX69_000740"
     CDS             35722..36438
                     /gene="atpB"
                     /locus_tag="VWX69_000740"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU9192126.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            36452..36946
                     /gene="atpF"
                     /locus_tag="VWX69_000741"
     CDS             36452..36946
                     /gene="atpF"
                     /locus_tag="VWX69_000741"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU9192127.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            36946..37482
                     /locus_tag="VWX69_000742"
     CDS             36946..37482
                     /locus_tag="VWX69_000742"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU9192128.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            37497..39002
                     /locus_tag="VWX69_000743"
     CDS             37497..39002
                     /locus_tag="VWX69_000743"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU9192129.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            39018..39896
                     /locus_tag="VWX69_000744"
     CDS             39018..39896
                     /locus_tag="VWX69_000744"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU9192130.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            39982..41388
                     /gene="atpD"
                     /locus_tag="VWX69_000745"
     CDS             39982..41388
                     /gene="atpD"
                     /locus_tag="VWX69_000745"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU9192131.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            41399..41818
                     /locus_tag="VWX69_000746"
     CDS             41399..41818
                     /locus_tag="VWX69_000746"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU9192132.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(41890..42435)
                     /locus_tag="VWX69_000747"
                     /pseudo
     CDS             complement(41890..42435)
                     /locus_tag="VWX69_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        13112 a         7876 c         9476 g        11971 t
ORIGIN      
        1 cggagcacaa ggtgctaaag gtgaaaaagg ggaccaaggt gaacgcggtc taaccggagc
       61 acaaggtgcc aaaggtgaaa aaggggacca aggtgaacgc ggtctaaccg gagcacaagg
      121 tgctaaaggt gaaaaagggg accaaggtga acaaggtctt caagggcgtg atggtgaaca
      181 aggaccaaaa ggagaagatg ggaaaaaccc aacagttaaa gtaactgatg gtcaagatgg
      241 aacgcataca attacaatta acgatggtaa aggtggtata actactacag tagtaagaga
      301 tggatttgat ggtgcaagcc ctcttgtttc tactcataga aatgaagcag ataaaacaac
      361 aactgttatt ttctattatg atctaaatga taataatcaa tttgatgaag gagatacaaa
      421 acttaaagaa gttgttatcg cagatggaaa acaaggacca aaaggtgaca aaggtgataa
      481 cggaaaagat ggattcacac cagaagtaac agttacagat aacaataacg gaacacacac
      541 catcacaatc acacaaccag acaacagacc atcattaaca acaatcgtta aaaacggtga
      601 agatggaaaa acaccaaaag tcaaagcaga acgagatgat gcgaagaaac aaacaacatt
      661 aacattctac attgacaaag atggagatgg aagttacaca gcaggaaaag acgagttagt
      721 tcaaacaaca gtagttaaag acggacaaga cggagctgca ggagcatctg gacgtgatgg
      781 aaaagaagta ttaaacggaa aagtagaccc aacaacagaa ggtaaagatg gagacacatt
      841 cgtaaataca caaacaggag atgtattcgt taagaaaggt aacacttggg aaccagcagg
      901 aaacatcaaa ggaccgaaag gtgacaaagg tgcagatggt gccaagggtg aaaaaggagc
      961 ccaaggagaa cgcggcctga ctggagcgca aggagctaaa ggtgcggatg gagcagcagg
     1021 tcgtgacgga cgtgatggac gtgacggtaa agacgtgttg aacggcaaag ttaacccaga
     1081 agcaaatcaa ggtaaagacg gtgataaata cgtcaataca gaaacaggcg acgtcttcgt
     1141 taagaataac ggcaactggg ataaagaggg caacatcaag ggacctaaag gggacaaagg
     1201 tgaacgcgga gaagatggta agactccaga agtaactgta actccaggta aagatggcca
     1261 tagtactgac attacattca ctgttccagg taaagatcca gttacagtaa atgttaagga
     1321 cggagaaaat ggtctgaacg gtaaaactcc aaaagttgat ttacttcgtg tccaaggaca
     1381 aaacggaaat ccacctcata caattgtgac attctataca gatgaaaaca atgatggcaa
     1441 atatacacca ggaactgatg aacttctagg ttcagaaatg attaaagatg gtgctaaagg
     1501 tgcggacgga cgagatggta aatcattgct tactgtcaag gatggtaaag aaactaaagt
     1561 ttaccaagaa gatccagcta acccaggaca accattaaat ccagaaaaac cacttgcggt
     1621 aattagagat ggagtagatg gaaaatcacc tacagttaca gctgttcgta aagatgaagc
     1681 agggcataaa ggtgtagaaa tcactgttga taaccatgat ggttcacaac caactacagt
     1741 ctttgttcaa gatggtgcta agggagaaac tggtgcaacc ggtcaagatg gacaaactcc
     1801 tacaatcact actcaacgtg gacaagatgg ccaaagcact gttgtaacta tcacaacatc
     1861 aggtaaagat ccagtaacct tcactgtaaa agatggtaag aatggtaaag atggccgtgc
     1921 accgaaaatc aaagtagaag atattacttc accttcaaga attagacgcg atacagatgc
     1981 tgctgcaact ccaacgcgta acggtatccg tgttacagtt tatgatgatg ttaatgacaa
     2041 tggggtatac gacgaaggtg tcgataaagt attaaatagt aaagatattt ataacggtat
     2101 agatggacgt gatggttcag ctccaactat tactacaaaa gataatggag atggaactca
     2161 cactatcaca gttcaaaacc cagatggttc tgaatcaaca acagttgtta aagatggtaa
     2221 agacggtaaa actgcgaata tcactacaac agaaaaccca gatggaagcc acacaattac
     2281 ggtgacaaat ccagatggtt caactaaaga aactgttgtt aaaaacggta aagacggtaa
     2341 gactcctaaa gttgaagtaa cggataacaa cgatggaact catactgtta aagttacaga
     2401 tggagacggc aatgttacca acgctatcat caaagatggt aaagacggta aagctgcaac
     2461 agcaacaact actgaaaatc cagatggaag ccacacagta acaatcacta acccagacgg
     2521 aactaagaat gagtttgttg ttaagaatgg acgtgacggt gttgacggac gtactccaac
     2581 cgcatctgtt cgtgataatg gagacggaag tcatacaatc gttattacaa atccagaagg
     2641 tgtgacaact gaaaccacag ttcgtgatgg taaatcacca aaagtgacta taactgatga
     2701 acaaaatgga actcataaga tctctgttct aaatggtgac ggaacaacta ctgaaacaat
     2761 cattaaagat ggtaaatcac caaaagcgaa catcgttgat aacggagatg gaactcatac
     2821 attaacaatc gtagattctg atggtcgtga atacaaatct attatcaaag atggtaaaga
     2881 cggcaaagat agcgtttcac caactgtaac tgttaaaaat aataacgatg gaactcacgt
     2941 tgttacaatc actaatccag atggaagtaa gacagaaatg gtgattaaag acggtaaaga
     3001 tggtaaatca ccaaaagttt ctgttgaaga taatggtgat ggtagtcata caatcacaat
     3061 catcaattct gatggaactg tgacaaaaac agttattaaa gatggcaaag atggtagaga
     3121 tggacgtgat ggtcgagacg gcaaagacgg taaagacggt aaagatggaa aatgtggatg
     3181 ccaagacaaa ccagtaacac catcaaatga caaaccagtt cctccaacac caaatgtgcc
     3241 gacaccagaa gtaccggtta aacctgtgcc agcgcaacca acaccaaatg taccgacacc
     3301 agaagtgcca gtacaaccaa ctccagctgt tccaacacca gaagtaccgg ttaaaccagt
     3361 accagcggtt ccagaacaac cagtagtacc aacaccggct caaccagcaa ctccagtaaa
     3421 tgctaatcca gtagcaccaa ctacaggtaa agaaaaccgt ggggacaaat tacctgaaac
     3481 tggaagccaa tctgattata tctctgttct tttaggtagc ggtattctat tgagcctata
     3541 tgtaggacga agaaaagaag attaatcagc caaaagcagt cactaatttc tcgaaagaag
     3601 atgataagtg atagatctcg aatgaaagaa tattcttaga atgattttcc tatgatggaa
     3661 aagactgcta aaaaccttga gtggtaacgc tcaaggtttt tttggatggc tgatgtttgt
     3721 ctgaaaatct tgattgagaa ataaaaagcc accctattag gtggctataa ttgatttaga
     3781 ctttctaaaa ttttctattt tttactgaat cgcttcgacc aagtcttgag cttgtttttc
     3841 aagtgagttt aggactgttt cttcaagaac caattttccg tctgcccagg cagagtcatt
     3901 aacacgtgca gcagtgaaat caccaacgcc ttgtgtacgg ataaatggca agaggtcttt
     3961 gtagatagcg aaaagttgat cgtgccctgc attggctaca gatgatactg tgacaaactt
     4021 gtcttgaagg gcagaaacgc cacgtgtatc agacaagtca agggcacgag atagccagtc
     4081 aagcaagttt ttcactgtac cagggataga gaagttgtag actggagaga aaatccagat
     4141 agcatccgca acgagaactg cttcacgagc agcagctaca gctggatgtg ttggaacttc
     4201 caaatcttgg ctgaagagag gaagggctga ataatcaagg tagctaactt ccgctttacc
     4261 agcaagtgct ttctcagctt cgagcgccat ttggtggttg aaagaacctt gacgtagtga
     4321 tccgacgata aataatactt ttttagacat gatgtgtctc ctttttctta aaatttcgag
     4381 aactctctcg ttgttataaa atatattaca acaaaacaaa agaacttgca agaaatttgc
     4441 tcagagttta tttgaaaatt gtaaaatttc ggaaactcta atcatttgtg actgaaaaag
     4501 taagaactgt ttcactttca aaatcggttt tgtttgaagg gagaaataga attggttgct
     4561 caaagcacag ctttgaggtt gcagataaag ctgacgtggt ttgaagagat tttcgaagag
     4621 tattcttata ttcacttgta ataaagctta atagatggta aaatagacga gtgaaaaaaa
     4681 gacaaaacaa agcaaaaaat aatctactgt ggcagtatgg tctagggatg acgattttgt
     4741 ttgtggttat cagtggttcc tttctgtata tggtttctct tagcatgaaa ccctatcaaa
     4801 cagctaaaag tgaaggagaa aaattagctc agcagtatgc aggattagag caggtcgatc
     4861 aggttgattt atacaatggc ttggaatctt attacagcgt tcttggtcgt aataaacagc
     4921 aagaagcgct tgctgtcctg attggtaaag atgaccataa gatttacgtt tatcagctaa
     4981 atcagggtgt ttcacaagaa aaagcagaaa cggtttctaa ggaaaaggga gctggcgaga
     5041 ttgacaagat aacctttggc cgttatcaag ataagccaat ctgggaagtt aagtcaggat
     5101 ctgattttta tctagtagat tttgaaacag gagcattggt caacaaggag ggcctatgaa
     5161 actatccaac cgtgttttag aaatggaaga aagtgtgact ttggctgctg gagcccgtgc
     5221 caaagcactg aaggctgagg gtagagatat tttgtctcta accttgggtg agccagattt
     5281 cactactccc aaaaatatcc aagatgccgc cattgcatcg attcgagatg ggcgtgcttc
     5341 tttttataca gtaacctcag gtctgccaga gcttaaggcg gcggtcaata gctactttga
     5401 gcgcttttac ggctattctg tagcgtcaaa tcaagtgaca gtcgctgcgg gagccaaata
     5461 ttctctctat accttcttta tggctgtggt caatccaggt gatgaagtca tcatcccaac
     5521 cccatactgg gttagctatg gagatcaggt caagatggca gaaggcgttc ccgtctttgt
     5581 ttctactaag gaagacaatc actttaaggt gaccgtagat cagttagaag cagctcgcac
     5641 tgacaagacc aaggttttgg tgctgaattc gccatctaat cccacaggta tgatttacac
     5701 ccgtgaggaa ctcttggcaa ttggaaactg ggctgtagaa aatgatattc tcatcctagc
     5761 agatgatatc tatggccgct tggtttataa tggtcatgag ttcacaccga tttctagcct
     5821 atcggaagcg attcgcaagc aaacagtggt catcaatggt gtgtctaaaa cctatgccat
     5881 gactggttgg cggattggtt atgccgttgg agaagcagat attatcgctg ccatgtccaa
     5941 gattgcaggt caaacaactt cgaatccgtc agcagtagcc caatatgcag cagttgaggc
     6001 tctatcaggt gagcaagata ctgtagaaag catgcgtcag gcctttgagg aacgtcttaa
     6061 taccatctat cccctccttg cagaggtacc aggatttgaa gtggtcaaac cgcaaggggc
     6121 cttctatctc ttcccaaatg tcaaaaaggc catggagatg aaaggctaca cggatgtgac
     6181 agactttaca actgctatct tagaagaagc cgaagtggcc ttggtaacag gagctggatt
     6241 tggagcacca gaaaatgtcc gcctcagcta tgcgacagac ctagacacgc ttaaagaagc
     6301 agtcgaacgc ttgaaagcat ttatgggtag tgagaatgat tgatcatttt gagattaagg
     6361 taaaggattt acaaatttca gaaggatttt ataggagttt tctcgctcct ttggactata
     6421 aattggcttt taagactagt tctctaatta gttttctatc cccgaacagc cctcatcctg
     6481 gtggtgattt ttggctgact cagggaacac aagatcctgt tcattttgct tttttagcag
     6541 aaaataagga agaagttcag gcttgttatg aggctggctt agaggcaggt gggcgagaca
     6601 atggggctcc tggttatcga agtgagcatc cgatttacta tgctgctttt atgattgacc
     6661 tggatgggaa caatatagag gtggtttgcc ataaagaata aaaaagaaaa ggaaaaataa
     6721 tgacaaaacg tgtaacgatt attgacgtaa aagactatgt tggtcaggaa gtgacgattg
     6781 gcgcttgggt tgccaacaaa tcaggaaaag gaaaaatcgc tttcttacaa ttgcgtgatg
     6841 gaacagcctt ctttcaaggt gtggctttta aaccaaactt tgtcgaaaaa tttggtgaag
     6901 aagtgggact tgagaagttt gatgttatca aacgcttgag ccaagaaacg tctgtttatg
     6961 tgacaggtat tgtcaaagag gacgaacgtt ctaaatttgg ctatgagttg gacatcacag
     7021 acatcgaagt gatcggtgaa tctcaagact acccaatcac accaaaagaa cacggaacag
     7081 actttttgat ggataaccgt cacttgtggc tacgctctcg taagcaagta gctgtgttgc
     7141 aaatccgtaa cgctattatc tatgcaactt atgagttctt tgacaagaac ggttttatga
     7201 agtttgacag cccaattctt tcaggaaatg cggcagaaga ttctacagaa ctctttgaaa
     7261 ctgactactt cggaacgcca gcctacttga gccaatcagg tcagctttac ctagaagcag
     7321 gggctatggc tcttggtcgt gtctttgact ttggtccagt tttccgtgct gaaaaatcaa
     7381 aaacacgccg tcacttgact gagttctgga tgatggatgc tgagtactca tacttgacac
     7441 atgatgagtc gcttgacttg caagaagctt atgtgaaagc tcttctacaa ggtgttcttg
     7501 accgcgcgcc tcaagccttg gaaaccttgg aacgtgatac agaactcttg aaacgctaca
     7561 ttgcagagcc attcaaacgt atcacttacg atcaagccat tgacctcttg caagagcatg
     7621 aaaatgatga agatgctgac tacgagcatc ttgagcatgg tgatgacttt gggtcaccac
     7681 acgaaacttg gatttcaaac cactttggtg tgccaacatt tgtcatgaac tatccagcag
     7741 ccatcaaggc cttctacatg aaaccagttc ctggaaatcc agagcgcgtg ctttgtgcag
     7801 acttgcttgc tccagaaggc tatggagaaa ttatcggtgg gtctatgcgt gaggaagatt
     7861 acgatgccct tgtcgctaag atggatgaac ttggcatgga tcgtacagaa tatgaattct
     7921 accttgacct tcgtaaatac ggtacagttc cacacggagg atttggtatc ggtatcgaac
     7981 gtatggtaac cttcgcagca ggaacaaaac atatccgtga agctattcca ttcccacgta
     8041 tgttgcaccg tatcaaacca taagaacagg aaaacgccca tgtggcgttt tttcgaattc
     8101 tagtgttttt acttgcgtaa aaaaattttt tctagtataa tagtttattg tgagcgaacc
     8161 tcacttaccc cttgcaaagt cttggggtca ttagaccaaa aggaggaaca tatcaatggc
     8221 taaatacgaa attctttata tcattcgtcc aaacattgaa gaagaagcta aaaacgcttt
     8281 ggtagcacgt tttgactcta ttttgactga caacggtgca actgttgttg aatcaaaaac
     8341 ttgggaaaaa cgtcgtcttg catacgaaat ccaagatttc cgtgaaggac tttaccacat
     8401 cgttaacgtt gaagcaaatg acgatgcagc tcttaaagag tttgaccgtc tttcaaaaat
     8461 caacgctgac attcttcgtc acatgatcgt caaaattgac gcgtaagaag gtaaactatg
     8521 attaacaatg ttgtacttgt agggcgtatg acacgtgacg ctgagttgcg ttatacccca
     8581 tcaaatgtag cagttgcgac ttttactctt gcagtaaacc gtacatttaa gagtcaaaat
     8641 ggtgaacgtg aggctgattt tatcaatgtc gttatgtggc gccaacaggc tgaaaatctt
     8701 gctaactggg ctaaaaaagg ctcacttatc ggggtgacag gtcgtatcca gactcgtagt
     8761 tacgataacc agcaaggaca acgtgtctac gtgacagagg tcgtggctga gaatttccaa
     8821 atgttggaaa gccgtagtgt gcgtgagggc cacacaggtg gagcttactc tgcaccaact
     8881 gcaaactatt cagcacctac aaattcagta ccagactttt cacgtaatga aaatccattt
     8941 ggagcaacaa acccattgga tatttcagat gatgatttac cattctaatg gacaactaaa
     9001 cttataaagg agaaaaaaca tggctcaaca acgtcgtggc ggattcaaac gccgtaaaaa
     9061 agttgattac atcgcagcaa acaaaattga atatgttgat tacaaagata ctgagcttct
     9121 tagccgtttc gtttcagaac gtgggaaaat ccttcctcgt cgtgtaacag gaacttcagc
     9181 taaaaaccaa cgtaaagtaa caacagctat caaacgcgct cgcgtaatgg ctttgatgcc
     9241 tttcgtaaac gaagattaaa gaaaagaccc ggttgggtct ctttttcatg agcttgaaaa
     9301 caagaaagcg aattaagacc ccaacgggtc ttttttcaca agctttgaaa tgagagagcg
     9361 agttaggctc agtggctccc tttttacgag tttgaaaaca agagaacaca ttaaaagcac
     9421 gatggagctt tttcataaat atgtcttttt tctcatccaa gaaattaaaa taaaaatgat
     9481 aaactttttg aaaatagggg atttgcctac tttatgatat aatggaaaga gttagattga
     9541 aagaggtagt gagatggacg cgaaattaag atacaaggca aagaagatca agattgtctt
     9601 ttttgatatt gatgatacat tgcggaattc aaagacaggg tttattccaa ctacaattcc
     9661 cactgttttt aaacagttgc gtgaaaaagg aattttaaca ggaatcgcct ctggacgtgg
     9721 catttttggt gttgttccag agattcgtga tctcaagcct gacttttttg taactttgaa
     9781 tggagcttat atcgaagata aaaaaggtca ggtcatttat cagcatcaga ttgaaaagtc
     9841 agatgttgag gagtatatct cttgggctaa gcaagaagga attgagtatg gcttggttgg
     9901 gagtcatgat gccaagttgt cgactcgcac cgatatgatg agtgaagcta tcaatccaat
     9961 ttatcccgac ttagatgtag atcccgattt ccatgaaaaa gaagatatct atcagatgtg
    10021 gacttttgaa gataagggag atgacttgca cttgcctgac agtctctcag acaaacttcg
    10081 catggttcgt tggcatcaac attcgtctga tattgtgccg atttcaggct ccaaagcgac
    10141 gggggtggaa aaggttgtgg aacaccttgg cttgaaacca gagaaggtca tggtttttgg
    10201 agatggtctc aacgacttgg aactctttga ttatgctgga atcagcgttg ccatgggaat
    10261 ttctcatgat aaaatcaaag aaaaagcaga ttatattaca aaaacattag aagaagatgg
    10321 catttttgat gccttagaag tatttggtat ggtagaaaaa gaattgcatt ttccacaagt
    10381 agacattgaa acagtagaag gtcctcttgc gactattaag accaatcacg gagacttacg
    10441 tatcaagctt ttccctgaac atgctcctaa aacagtggct aactttgtat ctctttcaaa
    10501 agatggctac tatgatggtg tcattttcca ccgtattatc aaggacttta tgatccaagg
    10561 tggagaccca actggaactg gtatgggtgg cgagtcaatc tacggcgaat cttttgagga
    10621 tgaattctca gaagagcttt acaatatccg tggtgctctt tccatggcaa atgctggtcc
    10681 aaataccaac ggcagccagt tctttatcgt gcaaaaccaa cacctacctt attcgaagaa
    10741 agaaattact cgtggtggtt ggccagaacc gattgcagaa atctatgcca atcaaggtgg
    10801 gacacctcac ctagaccgcc gtcacacggt ttttggtcag ttagctgatg aagcatctta
    10861 cgctgtcttg gatgccattg ctgctgttga gacaggagct atggacaagc cagttgaaga
    10921 tgttgtaatt gaaactattg aaatcgagga ctaagatgaa aatcggtgat aagctaaagg
    10981 ggcgtattac agggattcag ccctacggtg cctttgttga gttagagacg ggtgatacgg
    11041 ggctgattca catttcagaa attcggacag gatttattga aaatattcat gaaaccttga
    11101 aagtcgatga agaggttcaa gttcaggtag tggatttaga tgaatttacg gggaaagcca
    11161 gtctttctat ccgcactttg gaggaagaaa agtaccagtt tcctagacgg agacgctttt
    11221 caagcgaccg ctttaactac ggttttgctc cctttcgacg aatgctacca atctggactg
    11281 gagaagccct gcaccattta aaaaagaaga agtagtttag agttttatat tttttgtaat
    11341 gttaatatga atttgctata ataggaccat ggaagaagaa caattattaa aatcaggaga
    11401 gcgcattaac cagctctttt cgacagatat caaaatcatt caaaatagag aggtttttag
    11461 ctattcggtg gatagtgttc tcttatcacg atttccacgt tttcctaaga aggggttgat
    11521 tgtggatttc tgtgctggga atggagcagt ggggcttttt gctagcactc gtactcaagc
    11581 acagatattg tctgttgaga ttcaggagcg tttggcggat atggctgaac gctctgtccg
    11641 tttgaatgga ttagaggagc aaatgcaggt catctgcgat gatttgaaaa atatgcctgc
    11701 tcacattcag gggagtaagg tggatatgat tttgtgtaat ccaccctatt tcaaggtgaa
    11761 tccttattct aatctgaacg agagtgaaca ttatctcttg gctcgacacg aaatcacgac
    11821 taatttggaa gaaatctgtc gtagtgccca gagtattctc aagtctaatg ggcgtttggc
    11881 catggttcat cgtcctgatc gacttctgga tattttggat acgttaaaac gacataatct
    11941 agcccctaag cgcctgcagt ttgtttatcc aaaaagagaa aaggaagcca atatgctttt
    12001 gattgaggcg atcaaggatg gctcaacaag tggctttaag gtcttacctc ctttgattgt
    12061 ccacaatgat gatggctctt atacgcccga aatcgaagag atttattatg gatcataagg
    12121 cttatatgta cgttctggag tgtcgtgatg gatcctacta tataggctat acgactgata
    12181 tgagaagacg cctcgctatc cacaatagtg ggaagggagc caaatataca cgagcacgct
    12241 tgccagtcaa acttatctat gctcaaggtt ttgccagtaa ggaagaagcc atgtcggctg
    12301 aagctcttct caagcgtaag aagaggccac agaaggaaga atttttatct gaaaatcaag
    12361 atagaaattt actcagttat tttgaagaat cgtggggagt cctttgactc ctcttacctt
    12421 tgtcaaaaag cgaaaaaaat gctacaataa agaaaataaa caaaatgagg tattatcatg
    12481 tccaagattc tagtatttgg tcaccaaaat ccagactcag atgccatcgg atcatctgta
    12541 gcttttgcct accttgcaaa agaagcttac ggtttggata cggaagctgt tgcccttgga
    12601 actccaaatg aagaaacagc ctttgtcttg aactattttg gtgtggaagc accacgtgtt
    12661 atcacttctg ccaaagcaga gggggcagag caagttatct tgactgacca caatgaattc
    12721 caacaatctg tatcagatat cgctgaagta gaagtttacg gtgttgtaga ccaccaccgt
    12781 gtggctaact ttgaaactgc aagcccactt tacatgcgtt tggagccagt tggatcagcg
    12841 tcttcaatcg tttaccgtat gttcaaagaa catggtgtag ctgtgcctaa agagattgca
    12901 ggtttgatgc tttcaggttt gatttcagat acccttcttt tgaaatcacc aacaacacac
    12961 ccaacagata aaatcattgc tcctgaattg gctgaattgg ctggtgtgaa cttggaagaa
    13021 tatggtttgg caatgttgaa agctggtacc aacttggcta gcaaatctgc tgaagaattg
    13081 attgatatcg atgctaagac ttttgaactc aacggaaata atgtccgtgt tgcccaagtg
    13141 aacacagttg acatcgctga agttttggaa cgccaagcag aaattgaagc tgcaatgcaa
    13201 gctgccaacg aatcaaacgg ctactctgac tttgtcttga tgattacaga tatcgtcaac
    13261 tcaaactcag aaatcttggc tcttggtgcc aatatggaca aggtcgaagc ggctttcaac
    13321 ttcaaacttg aaaacaatca tgccttcctt gctggtgccg tttcacgtaa gaaacaagtg
    13381 gtacctcaat tgactgaaag ctttaatgcg taagattttg ggtgtcagct caaaatcgga
    13441 aagtctagtt tgccttatat cgaaaggagt ttcggctcct tttttctagg agtgaagtat
    13501 gttagaaaat ggcgatttga tttttgtgag agatgggtca gacatgggac aggccatcca
    13561 gacttccaca ggtaactata gccatgttgc catttatttg gatgggatga tttatcatgc
    13621 tagtggacag gctggtgttg tctgtcaaga accggcagac ttctttgagt ccaatcattt
    13681 atacgacctc tatgtttacc cagaaatgga tatccagtcg gtgaaggaaa gagcttgcaa
    13741 acatcttgga gcaccctaca atgcttcttt ctatccagat gcacctggtt tctactgctc
    13801 ccagtatata gcagaaatcc tacctatttt tgaaactatt cctatgaaat ttggagatgg
    13861 ggagcaggag attagtgatt tttggaggga gtattacata gaactaggtc tgcctgttcc
    13921 tctgaaccaa gctggtacca atcctagtca gttggcagca tcgcctctgt tacaatgtaa
    13981 agaaaggaat cttcatgatt cagattttta atccatctcg tttgacgaga cagccatttt
    14041 tggagaattg atccgctatc tggaccagta tgaggatgtg attctacggg aaattaaggc
    14101 tcaatttcca gatgttgcag ttgataaact catggaagag tatataaagg caggcttgat
    14161 tctacgtgaa aataagcgct attacctcaa ttttcctacg cttgaatcac ttgatagtct
    14221 tgaactggat caagagattt ttgtcagaga agctagtccg gtctatcaag ccttgttgga
    14281 gcagagtttt gagacggaat tgcgcaatca aatcaatgca gctattttag ttgaaaagac
    14341 ggactttgcg cgcattaaaa tgactctgtc caattatttt tacaaggtca aacagcagta
    14401 tcctttgaca gaaaaacagc aggagctcta tgacatttta ggagatgtta atcctgagta
    14461 tgcactcaag tatatgacgg cttttttgtt gaaatttctc aaaaaagacc agcttatgca
    14521 gaaatgccgt gatatctttg tggacagttt ggttgtctta ggctatattg tgcaaaatga
    14581 agatggaaag tatgagttgg ctatcgattt tgataaggag agattaactt tctacttagc
    14641 gtgatttctt gtttctgagt acattgtttg actttcctta gtattcggta taaactatat
    14701 gtaaccggta acacatatcg gaataaacta aaggagacaa tcatatgtca cttgaaaaca
    14761 aattggaaca agcaacaggc gctgtcaaag aaggttttgg taaagttact ggagacagca
    14821 agacagaact tgaaggagct gttgaaaaaa cagttgctaa ggcaaaagac gttgtagaag
    14881 acgcaaaagg tgctgtagaa ggtgccgttg aaggtttgaa aaacgttttt actaaagaat
    14941 aggaaaaaat caagggtttc attttccctt gattttttct attcttataa ataattttct
    15001 gcgacggctg tatctcctgg gtaggattct ttcttgccct ggatgatttg gtaacaatcg
    15061 gctcccttac ccgcaataat aactgcatct aattcgtgat ttgtgatagc cattgccgcc
    15121 ttgatggctt cttggcgatc cgcaatcttc tcaacaggat gattgatgta gctactaatt
    15181 tcatctgcaa tggccattgg gtcttcatag ttagggtcat cagcagtcag aaagacttga
    15241 atctcagggt gttgattgag gaggaggcca aagtccttac gacgactttc tcccttgttt
    15301 cctgttgatc ccagaaccag agcaatcttt ccggtttgat gagtttcaac cacattgatg
    15361 agttttttca gactatcccc attgtgggca tagtcgatga agaccttggc tccatttttc
    15421 tgagtgagga cttccatacg accaggaacg cgggttgcag cgatgccttt tttgatgtcc
    15481 tcaagacttg ctccgagacg gagacaagca agtccagcag caactgcatt ttcttggttg
    15541 aagttgccaa tgagttggat atcataatct ccagcgagtt tacccgtagc tgaaaagcta
    15601 aaggctttgg aattctcgat ttggttatca aattggctac catagaaatc atggtcttga
    15661 tctttaacct gttctttcaa gactgagaag tggtccatgt cactgttaat gatgactgct
    15721 cggctatttt ccatcaagag acgcttgtgg tagaaatagt cttcaaagct agggtgttca
    15781 atcgggccga tatggtctgg gctgatattg aggaaaactc ccacatcaaa ggttagacca
    15841 tagacacgtc tgaccagata ggattgactg gagacttcca tgatgaggtg ggtacggtca
    15901 ttttgcacag cctgattcat catgtcaaag aggtcaatac tctcaggggt tgtcaacgct
    15961 gacttaaaga aagtctcgcc atcaagagtt gtgttcatgg tcgacaacat agcaggtcga
    16021 tgcccttgag ataagatgtt ataggcgaaa taggctgctg ttgtcttacc cttagtacca
    16081 gtaaaggcaa ggagtttgag tttttcctgt ggattaccat agaactccat ggcaatcaaa
    16141 ctcatggctt tctttatatc gttcacaatg atgacaggga taccgacttc gtagtccttt
    16201 tcagctacat accaagctaa gccttgtgtt atagcagaaa gaaggtattc ttttttaaag
    16261 gcagcgcctt ttgcaaaaaa aagagtgtct tctgttactt ttcggctgtc gtagctgatg
    16321 ctatcaaaaa caactttgct gtagttgtag tggtaatgac cttggtcaat aatttcgcga
    16381 aaaaggccat ctttctttaa aatatctaat acagtttcaa tttttatcat actttctatt
    16441 gtaaaccgaa agtcgcaaat ttacaagtaa caaggaaaag tttataatgg aagataagga
    16501 gtttttccta gttatcaaaa ttgaatgagg aatctatgtc gcacgaaaac aatcaccagc
    16561 aggcccagat gttacggggg actgcttggc taacggctag taactttatc agtcgcctac
    16621 tcggggctgt ttacattatc ccttggtaca tctggatggg ggcttatgca gctaaggcaa
    16681 atggtctctt taccatgggt tacaatatct atgcttggtt cttgttggtt tcaacagcgg
    16741 ggattccagt tgcggtggcc aagcaagttg ccaagtataa taccatgcga gaagaagagc
    16801 atagctttgc cctgattcgg agcttcttag gctttatgac aggactaggc ctggtttttg
    16861 ctttagtctt gtatgtcttt gctccttggc tagcagactt gtctggcgtg ggcaaagact
    16921 tgatcccaat catgcaaagc ttggcttggg gagtcttgat tttcccgtct atgagtgtta
    16981 tccgaggatt tttccaaggg atgaataacc tcaaacccta tgccatgagc caaattgctg
    17041 agcaggtcat tcgtgttatc tggatgctcc tagcaacctt tatcattatg aagctcggtt
    17101 caggagatta tctagcagcc gttacccaat caacctttgc tgcctttgtc ggtatggtag
    17161 ccagttttgc agtcttgatt tatttccttg cccaagaagg ttcactcaaa agagtctttg
    17221 aaacaggaga taagattaac agtaagcgtc tcttggttga taccattaag gaagccattc
    17281 cttttatcct gacagggtct gccatccagc tcttccagat tttggatcag ctgaccttta
    17341 tcaatagtat gagctggttt accaactaca gcaatgagga cttggttgtc atgttttctt
    17401 atttctcagc caatcctaat aaaatcacga tgattttgat ttctgtaggg gtttcgattg
    17461 ggagtgttgg tttgccactt ttgacggaaa actatgtcaa gggggacttg aaagcagctt
    17521 ctcgtctggt tcaggacagt ctcaccctac tctttatgtt cttgctacca gcaacggttg
    17581 gagtggttat ggtaggagaa cctctatata cagtcttcta tggtaagcca gatagtttgg
    17641 ctctgggctt atttgtcttt gcagttttgc agtctattat tttaggcttg tacatggtct
    17701 tgtctccaat gcttcaggcc atgttccgca accgcaaggc cgttctctat tttatctatg
    17761 gttctattgc caagctagtc ttgcaactac ctaccatcgc cctcttccac agttatggtc
    17821 ctttgatttc aacaaccatt gctctcatca ttcctaacgt cttgatgtat cgggatattt
    17881 gtaaagtaac tggtgtcaag cgcaaggtga ttttgaagcg aaccatttta atcagtttgc
    17941 tgaccctagt catgtttctg ttaataggaa ccatccagtg gctgttagga tttttcttcc
    18001 aaccaagtgg acgtttgtgt agcttctttt atgtagctct tgtcggtgcc atggggggtg
    18061 gactttatat ggttatgagt ctgcgtacct atttattaga taaggtaata ggaaaagccc
    18121 aagcagatcg cctgcgagca aaatttaagc tttcgtaagg tagcatttat aaataaaagg
    18181 aataagttga acaatctttt aggagaactt gaagcttatt ccttttttag cgtaaaaata
    18241 gctaaaatta tatttcaaaa atagaaaatg aggctttttt cgattttttg gaaaaaatca
    18301 ttgactaaac aaactaaacg ttgtataata aaacaaatat ttaaagcagg aggttccgga
    18361 aatgaaaaag tctaagagca aatatctaac cttggcaggt cttgtcctgg gtacaggagt
    18421 tttattgagc gcgtgtggaa attctagcac ggcgtcaaaa acatacaact atgtttattc
    18481 aagtgatcca tctagcttga actatctagc agaaaaccgc gcagcaacat ccgatattgt
    18541 tgcaaatttg gtagacgggt tattagaaaa tgaccaatat gggaatatta ttccatcatt
    18601 agcagaggat tggactgttt ctcaggacgg tttgacctat acctacaaac ttcgtaagga
    18661 tgccaagtgg tttacttctg agggagaaga atatgcgcct gtaactgccc aggattttgt
    18721 gacaggtttg caatatgcag ctgataaaaa atcagaagcc ttgtatctag tgcaggactc
    18781 tgttgctggt ttggatgact atatcactgg taaaacaagc gacttttcaa ctgtcggtgt
    18841 caaggcactt gatgaccaaa cggttcaata tactttggtt aaaccagaac tttactggaa
    18901 ttcaaaaaca cttgcaacga tactttttcc tgttaatgca gatttcctga aatcaaaagg
    18961 ggatgatttt gggaaggcgg atccatctag tattttgtac aatggacctt tcttgatgaa
    19021 agcacttgtc tcaaaatctg ctattgaata taagaaaaac cctaattact gggatgctaa
    19081 gaatgtcttt gtagacgatg tgaaattgac ctactatgat ggtagcgacc aagaatcact
    19141 ggaacgtaat tttacagctg gtgcttatac tacggctcgt ctttttccta acagctccag
    19201 ctatgaaggg attaaagaaa aatacaaaaa caatatcatc tatagtgtgc aaaattcaac
    19261 ttcatatttc tttaatttta acctagatag gaagtcttac aattatactt ctaaaacaag
    19321 tgacattgaa aagaaatcga cccaggaagc agttctcaat aaaaacttcc gtcaggctat
    19381 caattttgct tttgacagaa catcttatgg ggctcagtct gaagggaaag aaggtgcaac
    19441 aaagattttg cgtaacctag tggttcctcc aaactttgtc agtatcaagg gaaaagactt
    19501 tggtgaagtt gtagcctcta agatggtcaa ctatggtaag gaatggcaag gtatcaactt
    19561 tgcggatggt caagaccctt actacaatcc tgagaaagcc aaggctaagt ttgcggaagc
    19621 taagaaagaa ctcgaagcaa agggtgttca attcccaatc cacttggata agactgtgga
    19681 agtaacagat aaagtaggca tacaaggagt tagttctatc aaacaatcaa ttgaatctgt
    19741 tttaggttct gataatgtag tgattgacat tcagcaatta acatcagatg agtttgacag
    19801 ttcaggctac tttgctcaaa cagctgctca gaaagactat gatttatatc atggcggttg
    19861 gggacctgat tatcaagacc cgtcaaccta tctcgatatt tttaatacta atagtggagg
    19921 agttctacaa aatcttggac tagagcctgg agaagccaat gacaaggcta aggcagttgg
    19981 actggatgtc tatactcaaa tgttggaaga agctaataaa gagcaagatc cagccaaacg
    20041 ttatgagaaa tatgctgata ttcaagcttg gttgattgat agttctttag ttcttccaag
    20101 tgtttcgcgt gggggaacac catcattgag aagaaccgta ccatttgctg ctgcctatgg
    20161 tttaaccggt acaaaagggg ttgaatcata taaatacctc aaagtacaag ataagattgt
    20221 cacaacagac gaatatgcaa aagccagaga aaaatggttg aaagaaaaag aagaatccaa
    20281 taaaaaagcc caagaagaat tggcaaaaca tgtcaaataa aatctaattg tagataagtt
    20341 tgtgtaagaa gtctttgtgc ttaaaaacgc ataatatcag gtatataaaa tcctagatgt
    20401 tatgcgtttt gttataggaa gatttattag attttatcct caaattgagt tattcccgac
    20461 tttatccgtt gaaatattat aaggagtatt tatgaaatta aaattattaa gagtagatac
    20521 taaggtgatt atggggagtt tcttacttgt tctgtctagt ctacttgctt tgttgcttcc
    20581 ccttatctta aagggtttaa tagatgggag ttctattgaa aatataggtt ccaaagtatt
    20641 tcaatcgttt ttgattttta ttggtcaagc cttgttttct tctattggtt actatctgtt
    20701 tagtcaatcg ggtgaaaaaa gatagcaaaa atcaggaaaa aagtgataga ggggttgatt
    20761 tatgcagaga aatccttctt tgataagagc caaagtgggg agttgacttc tgccattgtc
    20821 aatgacatga gtgtcattcg tgagttttta attacgactt tcccaaatat tattctgagt
    20881 ttagttatgg tacttggttc cattgtagtc ttatttagtc ttgattggaa tctttctcta
    20941 cttttattca tcactcttcc ttgtatgatg tttattatct tgcccctttc caatatcagt
    21001 gaaaagtata gtcgtcgttt acaggaggaa atcggatttt taacagggca attgactgaa
    21061 aagattcaag aacatgaatt aattaagact aaccaagcag agaaaagtgt acaggatgtt
    21121 ttggataatt gtattgaaag ggtacaaaac aattcactga aatcagatag ggttacttct
    21181 tttgagaccc cgtttgctct cttatttatc tttgcgacta tagttgtgat gctaacctat
    21241 gggggttatc gggtcagcgc aggatatata tctgtgggaa ccttggtttc gtttttgatt
    21301 tacctctttc aattacttaa tcctattagt aatatagcta attttgtaac tatttattct
    21361 agtagcaagg gatcttcagt tgcactggag aacttgcttg cagttcctaa agaaaaattt
    21421 gagggaggaa aatcggtatc aggacaaggg ttgaatttta accatgtcta ttttggttat
    21481 gatgaaaatc gacctgtctt aaaggatatt acttgttcaa ttttcaaggg gcaaaaaatt
    21541 gcttttgttg ggccatctgg atcaggaaaa tcaacgattg tgcgtttgtt agagcggttt
    21601 tataaaccgc tttcaggaga tattctaatg gagcaatcaa gtatatatga ttttaactta
    21661 aaagaatgga gaagtaaaat cgcttgggtt tcacaaaata atgtagtctt atctggcagt
    21721 attcgtgaca atctttgtct cggtttgaat cgcttagtaa ctgatgatga attgatgaaa
    21781 gtgctagact tagtatcact aggtgatgag attcgctcca tgaaagaggg actagatact
    21841 gaagttggtg aacgcggacg actcttgtca ggggggcgaa gccaaagact tcaaatagct
    21901 agagcctact taaaagatgc tgaaattctt atatttgatg aagccactgc taatcttgat
    21961 gcggattctg agtatgcgat tatcagtagc ctctattctg tactaaagga gaagacggtt
    22021 gtgattatag cgcatcgctt gtcaacggta aaagatgtgg attgtatttt cttcttagag
    22081 gaggggaaaa tcactggctc aggaactcat aaggaactac tggaaaatca tgagcgttat
    22141 gctcgttttg tgcaggagca aatgatagag tgaaggtgtc ttttgagatt caccatttta
    22201 tagtctatta aagggagcag gaaaaactcc ctttttatat agtttgaaac tataactagc
    22261 tcttgaaaag aagaaaatga gttgatgaaa ataagtggta caatagttac tatagatttg
    22321 gaggaattgt atgagcaagg aattacacat taacacaatt ttagcacaag cagggatcaa
    22381 gtctgatgag gcaacaggtg ctttggtgac accacttcat ttttcaacga cctatcagca
    22441 tccagagttt ggtcgatcta ctgggtttga ctatacgcgc actaaaaatc caactcgtag
    22501 taaggctgag gaagtcttgg cggctattga gtcagcagac tatgccctag cgactagctc
    22561 agggatgtca gctattgtac tggcctttag cgtctttcca gtaggaagta aggtcttggc
    22621 agtgcgtgat ctttacggtg gttcttttcg ctggtttaac caagtggagc aggaaggtca
    22681 tttccatttt acctatgcca atacagaaga agagttgatt gccgagttag aaaaggatgt
    22741 ggatgttctc tatatcgaaa ccccaaccaa tcccttgatg ttggaatttg atatcgaaaa
    22801 actagcaaaa ttggctcatg ctaagggtgc caaagtggtg gtggacaata ccttctatag
    22861 ccctatctac caacgtccga ttgaagatgg agcagatatc gttctccatt cagcaaccaa
    22921 gtatctagca ggccacaatg atgtcttggc tggagtggtt gtgaccaata gtttagaact
    22981 atacgagaag cttttttaca atcttaatac aacaggggca gtcttgtctc catttgacag
    23041 ctaccagttg cttcgtggtc tcaagacctt gtctcttcgt atggagcgct caacagctaa
    23101 cgcccaagaa gtggttgcct ttttgaagga ttctccagca gttaaggaag ttctctacac
    23161 tggtcgtgga ggcatgattt cctttaaagt agccgatgaa acacgcattc ctcatatttt
    23221 gaacagtctc aaggtcttct cttttgcgga aagtttgggt ggagtggaaa gtcttattac
    23281 ttatccaacg actcaaactc atgctgatat tccagcagaa gtacgccatt cttatggttt
    23341 gacagatgac ctcttgcgtt tgtctattgg gattgaggat gctagagatt tgattgcaga
    23401 tttgcgccaa gccttagaag gataagacaa agatgggaaa atatgatttt acaagcctgc
    23461 ccaaccgttt agggcaccat acctataaat ggaaagaaac agaaacggat agtgaagttc
    23521 taccagcttg gatagcggat atggactttg tagtcttgcc tgaaatccac caagccgtgc
    23581 aaacttacgc agaccaactg gtttatggtt atacctatgc cagtgaagac ttaattaagg
    23641 aagttcaaaa gtgggaagct acacaatacg gttacaactt tgacaaagag gctcttgtct
    23701 ttatcgaggg tgtggtacca gccatctcaa cagctattca aacctttaca aaagaaggcg
    23761 aggcggtttt aattaacacg cctgtctacc caccctttgc tcgcagtgtc aagttgaata
    23821 atcgtagatt gattactaat tccttagtgg aaaaggatag tctgtttgag attgactttg
    23881 accaacttga aaaggatttg gtggaagagg aggttaaact ctatgttctt tgcaaccctc
    23941 acaatcctgg tggacgtgtt tgggaaaaag aagtgttgga gaagattggc caactctgcc
    24001 aaaaacacgg tgttttgtta gtttcggatg agattcacca agatttgacc ctctttggtc
    24061 acaaacacca gtctttcaat accatcaatc ctgccttcaa aaattttgct atcgtcttga
    24121 gcagtgccac taaaacattt aatattgctg gaacaaaaaa ttcctatgca gtcattgaaa
    24181 atcctaagtt gagactggct ttccagaaac gcctgttggc caataatcag catgaaattt
    24241 caggcttggg ttatttggcg acagaagctg cctatcgata cggtaaagat tggctagagg
    24301 aactcaagca agtctttgaa gaccacatca attatgtggt ggatctattt ggaaaagaga
    24361 ctaaaatcaa ggtcatgaaa ccgcaaggta cctacttgat ttggcttgac ttttcagctt
    24421 atgacctgac tgatgaaaca ttgcaagagt tgttgagaaa tgaagccaag gttatcctca
    24481 accgtggttt ggattttgga gaggaaggaa gtctccatgc ccgcatcaat atagctatgc
    24541 ccaaatctct gttgcaagaa gtctgtcagc ggattgtggc tacttttgcc aaatgttaaa
    24601 aatccagcct tctaggagaa aagtcttcct agaaggctat tttcataggc gaaaatatgg
    24661 tataataaaa agataaggta aaggtgaaaa tatggctaaa ttgattccgg ggaaaattcg
    24721 tatcgaaggt gttgcccttt atgaaactgg taaggttgat atcatcaagg aaaagaacaa
    24781 tcggctctac gctcgcgttg cagaagaaga actgcgctat agtttagagg atgatttgat
    24841 tttttgtgcc tgtgattttt ttcaaaagag gggctactgt gtgcatttgg cagcgctaga
    24901 gcattttctg aaaaatgatg agcgtggtca ggaaatcttg tggagtctgg aagaaggtca
    24961 tgaagaaaaa gaggccgttg aaaccaaggt gaccttgggt ggcaagtttt tggatcgaat
    25021 tttatctcca aaatcagaat gcgcctatga gttatcagct gtgggtcagg tggaagcagg
    25081 aaccaatcat atcttgtgga ctctgagaat cggccaaatc aatagccaaa aatactatgt
    25141 cattcgggat attccacttt ttttaaggat tgtcgagcag agaaagtcgt atatgattgg
    25201 caagatttat gaggagtctc tttcttggga agcctttgat gatgccagcc aagaactttt
    25261 gactttcttg cacggactaa cggaggaagg gctggttcca gacctctttt tccaaaacca
    25321 aggtcggcac ctctttttcc ctctgacctt ttttgagcag ggtgtgaatt tactgatggc
    25381 cttgccccat tttcaatttg accatcaagt ggatagctac caaaccctgc tttttcagga
    25441 tatgcatgct gatgccaatc tatttgcctt tacagtaaca gaatattcgg actattttga
    25501 aatggaaatc agtgagagtc ctagggtcaa tgtcttttat caaggagcag tacttttcca
    25561 taaaggtcag gtttattttt taacagacca gcagatgcgt cttctcaagg aaattaaagc
    25621 gttacctgtg gatcgacaag gaaagaaata cctgcaattt gatagcagtg atcgagacaa
    25681 attggcctcc tgtctgactc tttttatcca gatgggcacc gtttcagctc cagaacgtct
    25741 acaaatcaaa acttttgcgc cctcttttta ctttgacagg gaagaagata atcggattcg
    25801 tttagaaatt cagtttgatt atggaaatag acaggtatct agccgacaag agctagaaga
    25861 attaccattt tcaagtgacg cggacttaga agaaagaatt ttccaagtct gtttggctgc
    25921 gggctttgaa gccgattttc aatcttggcg tcaggcctta aaagcggagt ctgtctatca
    25981 tttttttcat gatatcattc cagtctttga aaaactcggg catgttgacc tatcagataa
    26041 actagaagag ctttatagcc tagcgagtcc tcaggtgcag attgcctcca agggaggtct
    26101 cttggaaatc cagtttgatt ttcaagatat tgcccaggag gaaatcgacc aagccataca
    26161 ggccttggtt gccaatcagg atttttatat tgattcgtct aatcaagttt actttttcga
    26221 tgaagaaacc aagaaaattc gccaaaatct acaggaactg gggcaatttg aattaaaaga
    26281 tgggaccttg caggctcgga aatccttggc ctacagttta gctcatctct ttgaagggcg
    26341 agaccgtgtt tctttttcac aagaattcca gaatctggcc caggatttga cgcatccaga
    26401 ggactttcct ttgcaagcaa ctcaggtcaa ggctgacttg cgagattatc aggaaaaggg
    26461 aattggctgg ttgcagatgc tccatcatta tggttttggt gggattttgg ctgatgatat
    26521 gggacttggg aaaacccttc agaccattgc ttttttgact agtcaagtga caaaagaaag
    26581 tcgggttttg attctcgctc cgtcgggttt gatttacaac tgggcagatg agtttcagaa
    26641 atttgctcca cagttggatg tggctgttgt tcatggtttg aaagcaagtc gtgaggagat
    26701 tcttgccgag agccatcaaa tctatgtgac tagctatgcc accttccgtc aggacagtga
    26761 gctttatcag gggatggcct ttgacttcct tttcttagat gaagctcagg tcatgaaaaa
    26821 tgcccagacc aagattgccc agaccttgag acaatttgtg gtgccgtcgg tctttgcctt
    26881 gtcaggaact ccgattgaaa accatctggg tgagttgtgg tctatttttc aaatcgtcat
    26941 gcccggactt ttgccaagca agaaagaatt tatgaaattg ccagcagagc gagtggctca
    27001 gtttatcaag cctttcgtga tgcgacgcaa gaaagaagaa gttctgactg aattgccaga
    27061 cttgattgag gtggtttata aaaatgaact ggaagaccag caaaaggcta tttaccttgc
    27121 ccagttacaa cagatgcgag accatctggc tcaagtgtca gaacaggaat ttcagcgaag
    27181 tcgtgtggaa attttatctg gtttgatgcg cttgcgtcaa atatgtgaca ctcctgccct
    27241 gtttatggaa gattatcagg gagccagcgg caaactagat agtctccgag acctactggt
    27301 acaggtggca gacggcggac accgtgtctt gattttctct cagttcaagg gaatgttgga
    27361 aaaaattgaa caagaactgc cagacttggg cctgacatcc tttaaaatta cgggttcaac
    27421 cccagccaag gaaagacaag acatgaccaa ggcctttaac caaggagaaa gagatgcctt
    27481 tctgatttcc ctcaaggctg gtggggtcgg tctgaacctg acaggtgcag atacagtgat
    27541 cttggttgac ctttggtgga atcctgcggt ggaagcgcaa gccattggcc gtgcccatcg
    27601 gatgggtcag gaagaaacgg ttgaggtcta tcgcttggtg accaagggaa ccattgaaga
    27661 aaaaattcag gaactccaag aacaaaagaa acatctggtg tcacaagtat tggacggcac
    27721 agagtcacgt ggtagtctga ccctagcaga aattagagaa attttgggaa tttctgaagc
    27781 cagcacttga aaaatcaaga caatacgcta taatgaagtg ttgaaaggaa atagaaaatg
    27841 aaacaagaac gatttccatt ggtgtcagat gacgaggtca tgttgactga aatgccagtc
    27901 atgaatctct atgatgagtc tgatctgatc agtaatatca agggtgagta tcgagataaa
    27961 aattatttag aatgggctcc tattgctgaa gaaaaaccag taaaaccgat tgaaaagcaa
    28021 gtagggaaac ctaaaaaagc tcctttaggg gttaaaaaag aaggaaagag ctatgcggag
    28081 gtggcgcgtg aagaagcgcg tgcagacttg aaaaagaaac gctctgctaa ctatctaact
    28141 caggatttca gccttgcgag acgtcattct cagcccagtc tagttagaca gggcaatcaa
    28201 ccgacaactc ctttccaaaa ggaaaatcct ggtgaatttg tcaaatatag ccaaaaattg
    28261 acccagtctc attatatctt ggcggaagaa gttcattcta tccctaccaa gaatgaagaa
    28321 gtgtcagcac ctgctccaaa gaaaaacaat tatgattttc taaagaagag ccaaatctac
    28381 aataaaaaaa gtaaacaaac agaacaagaa cgtcgggttg cccaagagtt gaatctgacc
    28441 agaatgacag aataggggag aaaacatgtc aaagacatat cattttatcg gaattaaggg
    28501 atcagggatg agtgccttgg ccttgatgtt gtaccagatg gggcacaagg ttcagggatc
    28561 agatgttgaa aagtactact ttacccaacg cggtcttgag caggcaggaa ttaccattct
    28621 tccttttgat gaaaagaatc tagacggtga tatggaaatt atcgctggaa atgcctttcg
    28681 tccagataac aacgtcgaaa ttgcctatgc ggaccaaaat ggtatcagct acaaacgtta
    28741 ccatgagttt ctaggtagct ttatgcgtga ctttgttagc atgggagtag caggagcaca
    28801 tggaaaaact tcaacgacag gtatgttgtc tcatgtcttg tctcacatta cagataccag
    28861 cttcttgatt ggagatggga caggtcgtgg ttcggccaat gccaaatatt ttgtctttga
    28921 atctgacgaa tatgagcgtc acttcatgcc ttaccaccca gaatactcta ttatcaccaa
    28981 cattgacttt gaccatccag attatttcac aagtctcgag gatgttttca atgcctttaa
    29041 cgactatgcc aaacaaatca ccaagggtct ttttgtctat ggtgaagatg ctgaattgcg
    29101 taagattacg tctgatgcac caatttatta ttatggtttt gaagctgaag gcaatgactt
    29161 tgtagctagt gatcttcttc gttcaacaac tggttcaacc ttcaccgttc atttccgtgg
    29221 acaaaacttg gggcaattcc acattccaac ctttggtcgt cacaatatca tgaatgcgac
    29281 agccgttatt ggtcttcttt acacagcagg atttgatttg aacttggtgc gtgagcactt
    29341 gaaaacattt tccggtgtta aacgtcgttt cactgagaaa attgtcaatg atacagtgat
    29401 tatcgatgac tttgcccatc atccaacaga aattattgcg accttggatg cggctcgtca
    29461 gaaataccca agcaaggaaa ttgtagcagt ctttcaaccg cataccttta caagaaccat
    29521 tgccttgttg gacgactttg cccatgcttt aaaccaagca gatgctgttt atctagcgca
    29581 aatttatggc tcggctcgtg aagtagatca tggtgacgtt aaggtagaag acctagccaa
    29641 caaaatcaac aaaaaacacc aagtgattac tgttgaaaat gtttctccac tcctagacca
    29701 tgacaatgct gtttacgtct ttatgggagc aggagacatc caaacctatg aatactcatt
    29761 tgagcgtctc ttgtctaact tgacaagcaa tgttcaatag gatgttccca tggaaattcc
    29821 aattaagatc attcaggcaa gcaagtctga tttgcctgag ataggggcac ttcagacctc
    29881 gtcttttcca gctgaaaagc agcaactttc ccatatttta gaagaaagta tccgtaagtg
    29941 tgcggatacc tttcttctag ctagggatga aaatcaactt ttaggctata ttttatcaag
    30001 tccccagtca gacaatccgc aatatctaaa agtacattct ttagtcatcg agtctgacca
    30061 tcagagacag ggcttgggaa cacttcttct tgcagccttg aaagaggtgg cagttgagct
    30121 ggattacaaa gggattcgtt tggagagtcc tgatgagctg ctttcctatt ttgaaatgaa
    30181 cggttttgtt gatgaagaag caactttgct ctatgcaact agccagggct atagtatgat
    30241 ttggtttaat cccttttatc tggaggaaca atgaaaatca gacaagcaag attagaagat
    30301 ttggatcgga ttgttgaact tgaatttgaa aatttttcgg tagaagaagc cattcctcct
    30361 tctgtctttg aagcacattt gagagaaatt cagacctctt ttctggttgc tgaaaaagaa
    30421 ggaagaatca tgggttatat cgaaggacca gttggcctgc accgccatct gcaagaccag
    30481 tcttttacag aagaaataaa agactatagt catgagcctg gtggttatat ctctgtgacc
    30541 tgtctgtcta ttgccaagga ggcacaggga ctcggactgg gtcagaaatt gctgacagcc
    30601 ttgaaagaag ttgctcttga agatgagaga gatggcatta atctaacctg tcatgactat
    30661 ctcatcgcct actatgaaaa acatggattt gtcaacgaag gccagtccca gtcaaccttt
    30721 gcaggggaaa catggtatga tatggtctgg gaaatgaaaa aataagttag gaaaagtatc
    30781 atagattgct ttttttggac ttttaagata taatattatg gattatcaac aaggaggaaa
    30841 aacttttgag tgaaaagtca agagaagaag agaaattaag ctttaaagag cagattctga
    30901 gagatttaga aaaagtaaaa ggctatgatg aagttctgaa agaagatgag gcagtagttc
    30961 gcactcctgc aaatgaacct tcaactgaag aactcatggc tgattccttg tcaacggtag
    31021 aggagattat gagaaaagct cctaccgtgc ctactcaccc aagtcaaggt gtaccagctt
    31081 ctccagcaga tgagattcaa agagaaactc ctggtgttcc aagtcatcca agtcaagatg
    31141 taccttcttc tccagcggaa gaaagtggat caagaccagg tccaggtcct gttagaccta
    31201 agaaacttga aagagaatac aatgaaaccc caacaagggt agctgtttcc tatacgacgg
    31261 cagagaaaaa agcagaacaa gcaggtccag aaacacctac gcctgctaca gaaacagtgg
    31321 atatcatcag agatacatca cgtcgtagcc gtagagaagg agcaaaaccc gttaagccta
    31381 agaaagagaa gaagtcacat gtgaaagctt ttgtgatttc attccttgta ttccttgcct
    31441 tgctctcagc aggtggttac tttggttacc agtacgtgct agattcctta ttacctatcg
    31501 atgctaattc taagaaatat gtgacggttg gaattccaga aggttcaaac gttcaagaaa
    31561 tcggtacgac gcttgaaaaa gctggtttgg taaagcatgg tctgattttt agtttttatg
    31621 ccaagtataa aaattatacc gacttgaaag caggttacta caatttgcaa aagagtatga
    31681 gtacagaaga cttactcaaa gagttgcaaa aaggtggaac agatgaaccg caagaacctg
    31741 tacttgcgac tttgacaatt ccagaaggtt ataccttgga tcagattgct caagctgtgg
    31801 gtcaattgca aggtgacttc aaagagtctt tgacagcgga gactttcttg gctaaagttc
    31861 aagatgagac gtttatcagt caagcagtag cgaaatatcc tactttactg gaaagtttgc
    31921 ctgtaaaaga cagcggtgcg cgttatcgtt tggaaggata ccttttccca gctacatact
    31981 ctatcaagga aagcacaact attgagagct tgattgatga gatgttagct gctatggata
    32041 agaacctatc tccttactat agtactatca aatctaaaaa cttgactgtc aatgagttgt
    32101 tgaccattgc ttccttggtc gaaaaagaag gtgccaagac agaagatcgt aagctcattg
    32161 caggtgtatt ctacaatcgt ttgaatcgtg atatgccact tcaaagtaat attgcaatct
    32221 tgtatgccca aggaaaactg gggcaaaata tcagtctagc tgaggatgtt gcgattgata
    32281 ccaacattga ttcaccttat aatgtttata aaaatgtagg tctcatgcct ggtccagtcg
    32341 atagtccaag tctggatgcg attgagtcaa gcatcaatca aactaagagc gataacctct
    32401 actttgtagc agatgtcaca gaaggcaagg tctactatgc taacaatcaa gaagaccacg
    32461 accgcaatgt cgctgaacat gtcaacagca aattaaacta aacaaactaa aattatgtta
    32521 tacttcacat aattttcttt agaaaatatt atcagaagaa agttgagaaa aatggcagaa
    32581 aaaacatatc ctatgaccct tgaggaaaag gaaaaacttg aaaaagaatt agaagaattg
    32641 aaattggttc gtcgaccaga agtggtagaa cgcattaaga ttgcccgttc atacggtgac
    32701 ctttcagaaa acagtgagta cgaagcagct aaggatgaac aagcctttgt cgaaggacaa
    32761 atctctagct tagaaacaaa aatccgctat gctgaaatcg tcaatagcga cgcagttgcc
    32821 caggacgaag tagcgattgg taaaacagtc accatccaag aaattggtga ggacgaagaa
    32881 gaagtttata ttatcgtagg ttcagctggt gcggatgcct ttgcaggtaa ggtttcaaat
    32941 gaaagcccaa ttgggcaggc cttgattggc aagaaaacag gtgatacagc aaccattgaa
    33001 acgcctgttg gtagctatga tgtaaaaatc ttgaaggttg aaaaaacagc ctaaaaacag
    33061 aaaaaggagt ggggaggcga tgtgcttcac tcactccttt ttccattttg ctattcttcg
    33121 aaaatctctt caaaccacgt cagcgtcgcc ttgccgtatg tatggttact gacttcgtca
    33181 gtttcatcta caacctcaaa accatgtttt gagccgactt cgtcagtttc atctacaacc
    33241 tcaaaaccat gctttgagct gacttcgtca gtttcatcta caacctcaaa accatgcttt
    33301 gagctgactt cgtcagtttc atctacaacc tcaaaaccat gctttgagct gacttcgtca
    33361 gttctatcta caacctcaaa acagtgtttt gagcaacctg cggctagttt cctagtttgc
    33421 tctttgattt ttattgagta ttagatgtat agtgcattga agttaaaata gtacactttg
    33481 atttctaaga cattgttaga aattagatta aattccttaa tcgatttgcg catgttttat
    33541 ttcatttcac tatactttag attggaaaat aaggaatcac ataaatcgca agaaataggg
    33601 aatctgattc gtgtttataa ccgttcaaaa agagaagagg ctgaaagtga gccacttaat
    33661 ctttatgtcg aagatgaaaa gggcaatctc ctggcaggtt tgatagcaga gacttttgga
    33721 aattggctag aaatcgagta tttgtttgta aaagaggaac tgcgagggca aggaatcggt
    33781 tcaaaactat tgcaacaggc agaaagtgaa gctaagaatc gaaattgttg ttttgccttt
    33841 gtcaatactt accagttcca ggcaccggac ttttatcaga aacatggcta caaggaagtt
    33901 ttttctttgc aagactatct ctacattagg caaagatatt attaccaaaa gaatctgtaa
    33961 ggtgagtatg gaggtataat acaaagagag gctcgcacat aagtatggag gtggactgat
    34021 gtatatgagt aactatcgat aaataccagt tataacctag aaattgtgtc tttctagacg
    34081 atattgagga caatataatc gtagccccaa aattaggaat caagacttat caggttaaga
    34141 aaagaagtga tgttgttgat attttaaaca atttatttaa actaaaaact ctctatctat
    34201 taatccgaga ttcccctctc ggattttgtg ttgctttcat taaatttaca ggtaagactt
    34261 gctagcttca gtaaatatac acaagttttt cagaatagag tgaaatccaa aagaaaatgg
    34321 aaataatgaa agctcttgta ggcataagaa aacacctctg tgttatactt gttgttcaac
    34381 cacaaacaca agaaaggcac agagatgcaa gacaattata ctacaaaagc caaacatttg
    34441 acaatcgata gccgtcgctt aatcgaaaga tggaaaaaag aagggaaatc aaatagagaa
    34501 attgcctctc tgcttggaaa agttcctcaa actatccaca ctgaaatcaa gcgtgggaca
    34561 gtccgacaat gtcttggaaa agggcgcttc aaagaggttt attctgccga ctatgctcaa
    34621 cagtcttatg aaaataatcg caagcgctcg gtcaagaaat caagcttgac caaggaacta
    34681 aaggaaaaga ttctccacta tcataaccaa aaattttcgc ctgaaatgat ggtgatggct
    34741 aaaggggtta acgtgggaat ttcaaccatt tactattgga ttcatcatgg aaaattgggg
    34801 ttaagcaaac aggatctgct ttaccctaga aaaggaaaag cgcttaagaa acaggctagc
    34861 accaacttta aacctgctgg tcaatccatc gaacagcggt ctgaagctat caatcttcgc
    34921 ttggagaatg ggcattatga gattgatacg gttctactta cgagagcgaa aaactactgc
    34981 ttgcttgtct tgacggatcg aaagagtaga catcagatca tccgattgat tccaaataaa
    35041 agtgctgagg tggtcaatca ggctctaaaa ctcatcttaa aacaacacaa gattctttcc
    35101 atcacggcag ataatggaac ggaattcaat cgcttgtttg atgtattttc tgaggagcac
    35161 atctattatg cgcaccccta tgcctcttgg gaaaggggaa ctaatgagaa tcacaacagg
    35221 ctcattcgta gatggttacc taagggaacc aagaaaatga ctcccaaaga agtcgcattc
    35281 atcgaaaagt ggattaacaa ctatcctaaa aaatgcttgg actacaagtc acccagagaa
    35341 gacttctgga tggctaactt gaacttgaaa tttagcaaaa tggaaataat ttttattaaa
    35401 cgcttccaat agcggttaaa agttgacaaa tttaaatttt aggactacac taagtaagta
    35461 aattttattt taaaggagaa tttgttatga atttaacatt tttaggctta tgtattgcct
    35521 gtatgggcgt atctgtcggt gaaggtttat tgatgaatgg actgtttaaa tcagtagcac
    35581 gccaaccaga tatgctttct gagtttcgta gtttgatgtt tttaggtgtt gcctttattg
    35641 aaggaacttt ctttgtaact cttgtcttct catttattat caaataaata catggaacga
    35701 gaagaaaagg gaggatttta gatggaagaa agtattaatc caatcatctc tattggtcct
    35761 gttatcttca atctgactat gttagccatg actttgttga ttgtgggagt tatttttgtc
    35821 tttatttatt gggcaagccg caatatgacc ttgaaaccca aaggaaagca aaatgtactt
    35881 gagtatgtct atgactttgt tattggattt acagaaccta acattggttc gcgctacatg
    35941 aaagattact cactcttttt cctttgttta ttccttttca tggtgattgc caataacctt
    36001 ggcttaatga caaagcttca aacgatcgat gggactaact ggtggagttc gccaaccgct
    36061 aatttacagt atgacttaac cttatctttt cttgtcattt tgttgacaca tatagaaagc
    36121 gttcgtcgtc gtggatttaa aaaaagtata aaatctttta tgagtcctgt ttttgtcata
    36181 ccgatgaata tcttggaaga atttacaaac ttcttatctt tggctttgcg gatttttggg
    36241 aatatctttg caggagaggt catgacgagt ttgttacttc ttctttccca ccaagctatt
    36301 tattggtatc cagtagcctt tggagctaat ttggcttgga ctgcattttc tgtctttatt
    36361 tcctgcatcc aagcttatgt ttttactctt ttgacatctg tgtatttagg gaataagatt
    36421 aatattgaag aggaatagaa aggagtaact gatgcacgta acagtaggtg aattaattgg
    36481 taattttatt ttaatcactg gctcttttat tcttttgcta gtcttgatta aaaaatttgc
    36541 atggtctaat attacaggca ttttcgaaga aagagctgaa aaaattgctt cagatattga
    36601 cagagctgaa gaagcccgtc aaaaagcaga agtattggct caaaaacgcg aagatgaatt
    36661 ggctggtagc cgtaaagaag ctaagacaat cattgaaaat gcaaaggaaa cagctgagca
    36721 aagtaaggct aatatcttag cagatgctaa actagaagca ggacacttaa aagaaaaagc
    36781 caatcaagaa attgctcaaa ataaagtaga agctttacag agtgttaagg gtgaggtcgc
    36841 agatttgacc atcagcttag ctggtaaaat catctcacaa aaccttgaca gtcatgccca
    36901 taaagcactc attgatcagt atatcgatca gctaggagaa gcttaatgga caagaaaaca
    36961 gtaaaggtaa ttgaaaaata cagcatgcct tttgtccaat tggtacttga aaaaggagaa
    37021 gaagaccgta tcttttcaga cttgactcaa atcaagcaag ttgttgaaaa aacaggtctg
    37081 ccttcttttt taaaacaagt ggcagtagac gagtcggata aggaaaaaac aattgctttt
    37141 ttccaagatt ctgtgtcgcc tttattacaa aactttatcc aggttctggc ctacaatcac
    37201 agagcaaatc ttttttatga tgtgcttgta gattgcttga accgacttga aaaagaaaca
    37261 aatcgatttg aagtgacgat tacgtctgct catcctctaa ctgatgaaca gaagactcgt
    37321 ttgctccctt tgattgagaa aaaaatgtct ctgaaagtaa ggagtgtaaa agaacaaatc
    37381 gatgaaagtc tcattggtgg ttttgtcatt tttgccaatc acaagacaat tgatgtgagt
    37441 attaaacaac aacttaaagt tgttaaagaa aatttgaaat agaaagtggt gttcttttgg
    37501 caattaacgc acaagaaatc agcgctttaa ttaagcaaca aattgaaaat ttcaaaccca
    37561 attttgatgt gactgaaaca ggtgttgtaa cctatatcgg ggacggtatc gcgcgtgctc
    37621 atggccttga aaatgtcatg agtggagagt tgttgaattt tgaaaacggc tcttatggta
    37681 tggctcaaaa cttggagtca acagacgttg gtattatcat cctaggtgac tttacagata
    37741 tccgtgaagg cgatacaatc cgccgtacag ggaaaatcat ggaagtccct gtaggtgaaa
    37801 gtctgattgg tcgtgttgtg gatccgcttg gtcgtccagt tgacggtctt ggagaaatcc
    37861 acactgataa aactcgtcca gtagaagcac cagctcctgg tgttatgcaa cgtaagtctg
    37921 tttcagaacc attgcaaact ggtttgaaag ctattgacgc ccttgtaccg attggtcgtg
    37981 gtcaacgtga gttgattatc ggtgaccgtc agacagggaa aacaaccatt gcgattgata
    38041 caatcttgaa ccaaaaagat caagatatga tctgtatcta cgtcgcgatt ggacaaaaag
    38101 aatcaacagt tcgtacgcaa gtagaaacac ttcgtcagta cggtgccttg gactacacaa
    38161 tcgttgtgac agcctctgct tcacaaccat ctccattgct cttcctagct ccttatactg
    38221 gggttgctat ggcggaagaa tttatgtatc aaggtaagca tgttttgatt gtatacgatg
    38281 atctatcaaa acaagcggta gcttatcgtg aactatcgct cttgcttcgt cgtcctccag
    38341 gtcgtgaagc cttcccaggg gatgttttct atctccacag ccgtttgctt gagcgctcag
    38401 ctaaagtttc tgatgaactt ggtggtggat caattacagc cctaccattt atcgagacac
    38461 aagcaggaga tatctcagcc tatatcgcaa ccaacgtgat ttctatcact gatggacaaa
    38521 tcttccttgg cgatggcctc ttcaatgcag gtattcgtcc agccatcgat gcgggttcat
    38581 ctgtatctcg tgtaggtggt tctgcacaaa tcaaagccat gaagaaggtt gctggtacac
    38641 ttcgtatcga ccttgcttca taccgtgagt tggaagcctt tactaagttt ggttctgact
    38701 tggacgcagc aacacaggct aagttgaacc gtggacgtcg taccgttgag gtcttgaaac
    38761 aacctgttca caaaccatta cctgttgaga aacaagtaac cattctttat gctttgacac
    38821 atggtttctt ggatactgtt ccagtagatg atattgttcg tttcgaggaa gagttccatg
    38881 ccttctttga tgctcaacat ccagagattt tggaaaccat tcgtgataca aaagacttgc
    38941 cagaagaagc agtcttggat gctgcgatta cagagtttct caatcaatct agcttccaat
    39001 aagaatagag gtgtcagatg gcagtgtctc taaatgatat taaaacaaaa atcgcctcaa
    39061 caaaaaatac gagtcaaatc actaatgcca tgcaaatggt atcggctgct aagttaggtc
    39121 gctctgaaga agctgctcgc aacttccaag tttacgctca gaaagtgcgt aaacttttga
    39181 cagatatcct tcatggtaat ggagctggtg cttcaactaa tccgatgttg attagccgtt
    39241 ctgtgaagaa gacaggctat atcgttatca cttcagaccg cggtttggtt ggaggttata
    39301 attcctctat tttgaaagct gttatggagt tgaaagaaga ataccaccca gacggtaaag
    39361 gttttgaaat gatctgtatc ggtgggatgg gagctgattt ctttaaggct cgcggtattc
    39421 aaccacttta tgaattacgt ggcttggcag accaacctag ctttgatcaa gttcgtaaga
    39481 ttatttcaaa aactgttgaa atgtaccaaa atgaactctt tgatgagctt tatgtttgct
    39541 acaaccacca tgtcaatacg ctaaccagtc aaatgcgtgt ggaacaaatg cttccgattg
    39601 ttgacttgga tccaaatgaa gcggatgaag agtacagctt gacttttgaa ttggaaacca
    39661 gccgagaaga aattctggag cagttgttgc ctcagtttgc agaaagtatg atttacggtg
    39721 ccattatcga tgccaagaca gctgagaatg ctgcgggtat gacagccatg caaacagcga
    39781 cagataatgc taagaaagtc atcaatgatt tgacaattca gtataaccgt gccagacagg
    39841 cggcgattac acaagaaatt acagaaatcg tagcaggtgc tagtgcctta gaataggctc
    39901 tagtccagct cgtatgaaaa tgaacttagg acctagttga gctaggaacc gacagtatct
    39961 tatatagaat aggagaagga gatgagttca ggtaaaattg ctcaggttat cggtcccgtt
    40021 gtagacgttt tgtttgcagc aggggaaaaa cttcctgaga ttaacaatgc acttgtcgtc
    40081 tacaaaaatg acgaaagaaa aacaaaaatc gtccttgaag tagccttgga gttaggagat
    40141 ggtatggttc gtactatcgc catggaatca acagatgggt tgactcgtgg aatggaagta
    40201 ttggacacag gtcgtccaat ctctgtacca gtaggtaaag aaactttggg acgtgtcttc
    40261 aacgttttgg gagataccat tgatttggaa gctcctttta cagaagacgc agagcgtcag
    40321 ccaattcata aaaaagctcc aacttttgat gagttgtcta cctcttctga aatccttgaa
    40381 acagggatca aggttattga ccttcttgcc ccttacctta aaggtggtaa agttggactt
    40441 ttcggtggtg ccggagttgg taaaaccgtc ttaatccaag aattgattca caacattgcc
    40501 caagagcacg gtggtatttc agtatttact ggtgttgggg aacgtactcg tgaggggaat
    40561 gacctttact gggaaatgaa agaatcaggc gttatcgaga aaacagccat ggtctttggt
    40621 cagatgaatg agccaccagg agcacgtatg cgtgttgccc ttactggttt gacaatcgct
    40681 gaatacttcc gtgatgtgga aggccaagac gtgcttctct ttatcgataa tatcttccgt
    40741 ttcactcagg ctggttcaga agtatctgcc cttttgggtc gtatgccatc agccgttggt
    40801 taccaaccaa cacttgctac ggaaatgggt caattgcaag aacgtatcac atcaaccaag
    40861 aagggttctg taacctctat ccaggctatc tatgtgccag cggatgacta tactgaccca
    40921 gcgccagcaa cagccttcgc tcacttggat tcaacaacaa acttggaacg taaattggta
    40981 caattgggta tctacccagc cgttgaccca cttgcttcaa gctcacgtgc cttggcacct
    41041 gaaatcgttg gagaagagca ctatgcagtt gctgctgaag taaaacgtgt ccttcaacgt
    41101 taccatgaat tgcaagatat cattgctatc cttggtatgg atgagctttc tgatgaagaa
    41161 aagaccttgg ttgctcgcgc ccgtcgtatc cagttcttct tgtcacaaaa cttcaacgtt
    41221 gcggaacaat ttactggtca gccaggttct tatgttccag ttgctgaaac tgtacgtggc
    41281 tttaaggaaa tccttgatgg taaatacgac cacttgccag aagatgcctt ccgtggtgta
    41341 ggttctatcg aagatgtgat tgcaaaagct gaaaaaatgg gattttaaga ggtgacctat
    41401 ggctcagtta actgtccaga tcgtgacacc agatggtctc gtctatgatc accatgccag
    41461 ctatgtatcg gttcgaactc tggatggtga gatggggatc ttgccacgac atgaaaatat
    41521 gattgcggtt ttagcagttg atgaagtaaa ggtaaaacgt atcgatgata aagatcacgt
    41581 gaactggatt gcagtaaacg gtggcgttat tgaaattgcc aatgatatga tcacaatcgt
    41641 cgctgactct gcagaacgtg ctcgtgatat cgatattagc cgtgcagaac gtgccaaact
    41701 tcgtgcagaa cgtgcaattg aagaagcaca agacaaacat ttgattgacc aagaacgtcg
    41761 tgctaagatt gctttgcaac gtgccattaa ccgtattaat gtcggaaata gactataaga
    41821 aaaaatgaac ttgaaaatac caagttcatt ttttaggctc tttgtcaact gtagtgggtt
    41881 gaaaaaaagc taagctcgag aaaggacaaa ttttgtcctt tcttttttga tattcagagc
    41941 gataaaaatc cgttttttga agttttcaaa gttccgaaaa ccaaaggcat tgcgcttgat
    42001 aagtttgatg agattattgg tcgcttccaa tttggcgttt gaatagggta gttgaagggc
    42061 gttgacgatt ttctctttgt cctttagaaa ggttttaaag acagtctgaa aaataggatg
    42121 aacctgctta agattgtcct caataagtcc gaaaaatttc tctggttcct tattctgaaa
    42181 gtgaaacagc aagagttgat agagctgata gtgatgtttc aagtcttgtg aatagctcaa
    42241 aagcttgtct aaaatctctt tattggttaa atgcatacga aaagtaggac gataaaatcg
    42301 cttatcactc agtttacggc tattctgttg tatgagcttc cattagcgct tgatagcctt
    42361 gtattcatgg gattttcgat gaaactgatt catgatttga acacgcacac gactcatagc
    42421 acggctaaga tgttg
//
LOCUS       DAVKBK010000013        40847 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVKBK010000013 DAVKBK010000000
VERSION     DAVKBK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.013"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            19..462
                     /locus_tag="VWX69_000748"
     CDS             19..462
                     /locus_tag="VWX69_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9192133.1"
                     /translation="MFCLEADNQEHLFDQVATLLEEREIVTPTYREALITREKSFPTG
                     LDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGKEVEVSLLFFII
                     NNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            500..805
                     /locus_tag="VWX69_000749"
     CDS             500..805
                     /locus_tag="VWX69_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9192134.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            853..2328
                     /locus_tag="VWX69_000750"
     CDS             853..2328
                     /locus_tag="VWX69_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU9192135.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            2678..9379
                     /locus_tag="VWX69_000751"
     CDS             2678..9379
                     /locus_tag="VWX69_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU9192136.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9627..10483)
                     /locus_tag="VWX69_000752"
                     /pseudo
     CDS             complement(9627..10483)
                     /locus_tag="VWX69_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10694..11053)
                     /locus_tag="VWX69_000753"
     CDS             complement(10694..11053)
                     /locus_tag="VWX69_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU9192137.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            11145..12101
                     /locus_tag="VWX69_000754"
                     /pseudo
     CDS             11145..12101
                     /locus_tag="VWX69_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            12085..12642
                     /locus_tag="VWX69_000755"
     CDS             12085..12642
                     /locus_tag="VWX69_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9192138.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12635..12889
                     /locus_tag="VWX69_000756"
     CDS             12635..12889
                     /locus_tag="VWX69_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192139.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12901..14955
                     /locus_tag="VWX69_000757"
     CDS             12901..14955
                     /locus_tag="VWX69_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU9192140.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            15134..15994
                     /locus_tag="VWX69_000758"
     CDS             15134..15994
                     /locus_tag="VWX69_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU9192141.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            16205..16915
                     /gene="ccdA2"
                     /locus_tag="VWX69_000759"
     CDS             16205..16915
                     /gene="ccdA2"
                     /locus_tag="VWX69_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9192142.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16935..17501
                     /locus_tag="VWX69_000760"
     CDS             16935..17501
                     /locus_tag="VWX69_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU9192143.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            17512..18624
                     /gene="msrB"
                     /locus_tag="VWX69_000761"
     CDS             17512..18624
                     /gene="msrB"
                     /locus_tag="VWX69_000761"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9192144.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISEDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            18892..19629
                     /locus_tag="VWX69_000762"
     CDS             18892..19629
                     /locus_tag="VWX69_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9192145.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            19626..21317
                     /locus_tag="VWX69_000763"
     CDS             19626..21317
                     /locus_tag="VWX69_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9192146.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            21433..21996
                     /locus_tag="VWX69_000764"
     CDS             21433..21996
                     /locus_tag="VWX69_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU9192147.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            22018..27687
                     /locus_tag="VWX69_000765"
     CDS             22018..27687
                     /locus_tag="VWX69_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEU9192148.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEALKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADI
                     EVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPY
                     GAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRIS
                     EEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            27748..29469
                     /gene="pabB"
                     /locus_tag="VWX69_000766"
     CDS             27748..29469
                     /gene="pabB"
                     /locus_tag="VWX69_000766"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU9192149.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            29589..31115
                     /locus_tag="VWX69_000767"
     CDS             29589..31115
                     /locus_tag="VWX69_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9192150.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKTKPTVQSGWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYV
                     QNAWVGNYYLKSGGYMAKSEWIYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAK
                     SEWVYDSNYKSYYYLTSEGSYARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK
                     "
     gene            31202..32121
                     /locus_tag="VWX69_000768"
                     /pseudo
     CDS             31202..32121
                     /locus_tag="VWX69_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            32256..33215
                     /locus_tag="VWX69_000769"
     CDS             32256..33215
                     /locus_tag="VWX69_000769"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU9192151.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            33312..34151
                     /locus_tag="VWX69_000770"
     CDS             33312..34151
                     /locus_tag="VWX69_000770"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU9192152.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(34199..34369)
                     /locus_tag="VWX69_000771"
     CDS             complement(34199..34369)
                     /locus_tag="VWX69_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU9192153.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            34490..35374
                     /gene="miaA"
                     /locus_tag="VWX69_000772"
     CDS             34490..35374
                     /gene="miaA"
                     /locus_tag="VWX69_000772"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU9192154.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            35367..36605
                     /gene="hflX"
                     /locus_tag="VWX69_000773"
     CDS             35367..36605
                     /gene="hflX"
                     /locus_tag="VWX69_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU9192155.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            36598..37221
                     /locus_tag="VWX69_000774"
     CDS             36598..37221
                     /locus_tag="VWX69_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU9192156.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            37236..38165
                     /locus_tag="VWX69_000775"
     CDS             37236..38165
                     /locus_tag="VWX69_000775"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU9192157.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            38186..38941
                     /locus_tag="VWX69_000776"
     CDS             38186..38941
                     /locus_tag="VWX69_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9192158.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(38995..39903)
                     /locus_tag="VWX69_000777"
     CDS             complement(38995..39903)
                     /locus_tag="VWX69_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9192159.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            39967..40236
                     /locus_tag="VWX69_000778"
     CDS             39967..40236
                     /locus_tag="VWX69_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU9192160.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            40236..40616
                     /locus_tag="VWX69_000779"
     CDS             40236..40616
                     /locus_tag="VWX69_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9192161.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
BASE COUNT        12676 a         7455 c         9018 g        11698 t
ORIGIN      
        1 ttctttgaca aaaaccttgt gttttgctta gaagcggata atcaagaaca tctctttgat
       61 caggttgcaa ctttattgga agaacgagaa attgtaactc caacttatcg tgaagccttg
      121 atcacgcgtg aaaagtcatt tccaactggt ttagatatgg aatttctagg aaaggacttg
      181 ccaaatgtag cgattcctca cacagatatt gttcataatc tagctgagaa agtggtggtt
      241 gttcgattag aaaaaccagt aacttttcac aatatgattg cgccaggtaa ggaagtagaa
      301 gtatctctac tcttctttat cattaacaat tcaagttcaa gtcaaacgaa cattctggct
      361 cagttgatgg actttttcac aggaaatggt catcttgaag acctatcaaa aatttctgaa
      421 ccagaaaaac tttatgctta cattgctgaa gcaaccgctt aatcttgtct attaaaaaat
      481 aaaatcggag gaaatccaaa tgattaaaat tcttgctgcc tgcggtgcag gtgttaactc
      541 aagtcaccaa attaaaagtg ctctagaaga agaactttca aaccgtggtt atgatgttca
      601 ctgtgatgca gtcatggtga aagatgtaaa cgaagacctt atgaaaggtt acgatatctt
      661 tacaccaatc gctgcaacag accttggttt tgaaccaggt atcccagtta tcgaagctgg
      721 gccaatctta ttccgtatcc cagcaatgag cgctccagta tttgacaata ttgaagcagc
      781 tattaaagaa catggattaa gctaattcta atttgttaac attcatataa cataaaaaag
      841 ggaggaactg ttatggatgc aatctttgac ctaatcggaa aggttttcaa tcccatctta
      901 gaaatgggtg gacctgtcat catgttgatc attttgacag tattggcttt actttttgga
      961 gtgaaattct ccaaagcgct tgaaggtggt atcaaacttg ccatcgctct tacaggtatc
     1021 ggtgctatca tcggtatgct aaatggtgct ttctcagcat cacttgcaaa attcgttgaa
     1081 aacactggta tccaattgag tattacagac gttggttggg caccactcgc aacaatcact
     1141 tggggttctg cttggacact atacttcttg ctcatcatgt tgattgtcaa cgtagtgatg
     1201 cttgctatga agaaaaccga tacacttgat gtcgatatct ttgatatctg gcacttgtct
     1261 atcacaggtc tcttgattaa atggtatgct gataacaatg gtgtgagtca aggggtttca
     1321 ctctttattg ctacagcagc tatcgtcctt gtcggtgtgt tgaaaattat caactctgac
     1381 ttgatgaaac ctacatttga tgaccttctt aacgccccaa gttcatcacc aatgacatca
     1441 actcacatga actacatgat gaacccagtt atcatggttt tggataagat ttttgaaaaa
     1501 ttcttcccag gccttgataa atatgacttt gatgctgcta aattgaacaa gaaaatcggt
     1561 ttctggggat ctaaattctt catcggtttc atccttggta tcgttatcgg tattatggga
     1621 actccacatc caattgcagg tgttgcagat gcagataaat ggcgtcttgt tatcaaagga
     1681 tggttgtctc ttggtttgac tgccggtgta tctttggaac tcttctcact tatcggttca
     1741 tggttcatcg cagccgtaga accactatca caaggtatta caaacgttgc tactaaacgt
     1801 cttcgaggac gtaaattcaa tatcggtctt gactggccat tcatcgctgg tcgtgctgaa
     1861 atctgggctt gtgccaacgt acttgcacca atcatgttga ttgaagcagt gcttctttca
     1921 aaagttggaa atggtatctt gccacttgca ggtatcatcg ctatgggtgt tactccagct
     1981 ctcttggttg taactcgtgg taaattgctc cgtatgatta tcttcggaac actcttgttg
     2041 ccactcttcc ttctttcagg tacacttatt gcaccatttg caacagaact tgctaaaggt
     2101 gtaggtgcct tcccagaagg tgtgagccaa actcaattga ttactcactc tactcttgaa
     2161 ggaccaatcg aaaaacttct tggttggaca attggtaaca ctacaactgg tgatatcaaa
     2221 gcaatccttg gtgcagtagt cttccttgta ttctatatcg gtatctttgc ttggtacaga
     2281 aaacaaatga tcaaacgtaa cgaagagtac gcagcaaaag caaaataatg cgctcctata
     2341 aaatataaac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctaaaa
     2401 acacagtttt gaggttgtag ataagactga cgaagtcagc tcaaaacatg gttttgaggt
     2461 tgtagatgaa actgacgaag tcagctcaaa acatggtttt gaggttgtag atgaaactga
     2521 cgaagtcagt aatcatatct acggcaaggc gacgctgacg aagtttgaat tggattttcg
     2581 cagagtgtaa attgttgaaa ctaggttgtc ataccatgta taccacttgg gctttggtag
     2641 tagctaactg cactaaatat aatataagga gggttttatg gggaaaggcc attggaatcg
     2701 gaaaagagtt tatagcattc gtaagtttgc tgtgggagct tgctcagtaa tgattgggac
     2761 ttgtgcagtt ctattaggag gaaatatagc tggagaatct gtagtttatg cggatgaaac
     2821 acttattact catactgctg agaaacctaa agaggaaaaa atgatagtag aagaaaaggc
     2881 tgataaagct ttggaaacta aaaatgtagt tgaaaggaca gaacaaagtg aacctagttc
     2941 aactgaggct attgcatctg agaagaaaga agatgaagcc gtaactccaa aagaggaaaa
     3001 agtgtctgct aaaccggaag aaaaagctcc aaggatagaa tcacaagctt caagtcaaga
     3061 aaaaccgctc aaggaagatg ctaaagctgt aacaaatgaa gaaatgaatc aaatgattga
     3121 agacaggaaa gtggatttta atcaaaattg gcactttaaa ctcaatgcaa attctaagga
     3181 agccattaaa cctgatgcag acgtatctac gtggaaaaaa ttagatttac cgtatgactg
     3241 gagtatcttt aacaatttcg atcatgaatc tcctgcacaa aatgaaggtg gacaactcaa
     3301 cggtggggaa gcttggtatc gcaagacttt caaactagat gaaaaagacc tcaagaaaaa
     3361 tgttcgcctt acttttgatg gcgtctacat ggattctcaa gtttatgtca atggtcagtt
     3421 agtggggcat tatccaaatg gttataacca gttctcatat gatatcacca aataccttca
     3481 caaagatggt cgtgagaatg tgattgctgt ccatgcagtc aacaaacagc caagtagccg
     3541 ttggtattca ggaagtggta tctatcgtga tgtgacttta caagtgacag ataaggtgca
     3601 tgttgagaaa aatgggacaa ctattttaac accaaaactt gaagaacaac aacatggcaa
     3661 ggttgaaact catgtgacca gcaaaatcgt caatacggac gacaaagacc atgaacttgt
     3721 agccgaatat caaatcgttg aacgaggtgg tcatgctgta acaggcttag ttcgtacagc
     3781 gagtcgtacc ttaaaagcac atgaatcaac aagcctagat gcgattttag aagttgaaag
     3841 accaaaactc tggaccgttt taaatgacaa acctgccttg tacgaattga ttacgcgtgt
     3901 ttaccgtgac ggtcaattgg ttgatgctaa gaaggatttg tttggttacc gttactatca
     3961 ctggactcca aatgaaggtt tctctttgaa tggtgaacgt attaaattcc atggagtatc
     4021 cttgcaccac gaccatgggg cgcttggagc agaagaaaac tataaagcag aatatcgccg
     4081 tctcaaacaa atgaaggaga tgggagttaa ctctatccgt acaacccaca accctgctag
     4141 tgagcaaacc ttgcaaatcg cagcagaact aggtttactc gttcaggaag aggcctttga
     4201 tacgtggtat ggtggcaaga aaccttatga ctatggacgt ttctttgaaa aagatgccac
     4261 tcacccagaa gctcgaaaag gtgaaaaatg gtctgatttt gacctacgta ccatggtcga
     4321 aagaggcaaa aacaaccctg ctatcttcat gtggtcaatt ggtaatgaaa taggtgaagc
     4381 taatggtgat gcccactctt tagcaactgt taaacgtttg gtcaaggtta tcaaggatgt
     4441 tgataagact cgctatgtta ccatgggagc agataaattc cgtttcggca atggtagcgg
     4501 agggcatgag aaaattgctg atgaactcga tgctgttgga tttaactatt ctgaagataa
     4561 ttacaaagcc cttagagcta agcatccaaa atggttgatt tacggttcag aaacatcatc
     4621 agcaacccgt acacgaggaa gttactatcg ccctgaacgt gaattgaaac atagcaatgg
     4681 acctgagcgt aattatgaac agtcagatta tggaaatgat cgtgtgggtt gggggaaaac
     4741 agcaaccgct tcatggactt ttgaccgtga caacgctggc tatgctggac agtttatctg
     4801 gacaggtacg gactatattg gtgaacctac accatggcac aaccaaaatc aaactcctgt
     4861 taagagctct tactttggta tcgtagatac agccggcatt ccaaaacatg acttctatct
     4921 ctaccaaagc caatgggttt ctgttaagaa gaaaccgatg gtacaccttc ttcctcactg
     4981 gaactgggaa aacaaagaat tagcatccaa agtagctgac tcagaaggta agattccagt
     5041 tcgtgcttat tcgaatgctt ctagtgtaga attgttcttg aatggaaaat ctcttggtct
     5101 taagactttc aataaaaaac aaaccagcga tgggcggact taccaagaag gtgcaaatgc
     5161 taatgaactt tatcttgaat ggaaagttgc ctatcaacca ggtaccttgg aagcaattgc
     5221 tcgtgatgaa tctggcaagg aaattgctcg agataagatt acgactgctg gtaagccagc
     5281 ggcagttcgt cttattaagg aagaccatgc gattgcagca gatggaaaag acttgactta
     5341 catctactat gaaattgttg acagccaggg gaatgtggtt ccaactgcta ataatctggt
     5401 tcgcttccaa ttgcatggcc aaggtcaact ggtcggtgta gataacggag aacaagccag
     5461 ccgtgaacgc tataaggcgc aagcagatgg ttcttggatt cgtaaagcat ttaatggtaa
     5521 aggtgttgcc attgtcaaat caactgaaca agcagggaaa ttcaccctta ctgctcactc
     5581 tgatctcttg aaatctagtc aagtcactgt ctttactggt aagaaagaag gacaagaaaa
     5641 gactgttttg gggacagagg tgccaaaagt acagaccatt attggagagg cacctgaaat
     5701 gcctaccact gttccgtttc tatacagtga tggtagtcgt gcagaacgtc ctgtaacctg
     5761 gtcttcagta gatgtgagca agcctggtat tgtaacggtg aaaggtatgg ctgacggacg
     5821 agaagtagaa gctcgtgtag aagtgattgc tcttaaatca gagctaccag ttgtgaaacg
     5881 tattgctcca aatactgact tgaattctgt agacaaatct gtttcctatg ttttgactga
     5941 tggaagtgta caagagtacg aagtagatag ctgggagatt acggaagtag ataaagccaa
     6001 actttcagta gctggatcac gtattcaaat gactggtcag ttagctggag aaactattca
     6061 tgcaaccctt gtggtagaag aaggaaatgc tgcagcacct gtagtgccaa ctgttactgt
     6121 tggaggtgaa gcagtaacag gtcttactag tcgacaacca atgcaatatc gtactctatc
     6181 ttatggtgcc caattgccag aagtcacagc aagtgctgaa aatgctgatg tgacagttct
     6241 tcaagcaagc gcagcaaacg gcatgcgtgc aagcatattt gttcagccta aagatggtgg
     6301 ccctcttcaa acctatgcaa ttcaattcct agaagaagca ccaaaaattg ctcacttgag
     6361 cttgcaagtg gaaaaagctg acagtctcaa agaagaccaa actgtcaaat tgtcggttcg
     6421 agctcactat caagatggaa cgcaagctgt attaccagct gataaagtaa ccttctctac
     6481 aagtggtgaa ggggaagtcg caattcgtaa aggaatgctt gagttgcata agccaggagc
     6541 agtcactctc aaagcggaat atgagggagc taaaggccaa gttgaactca ctatccaagc
     6601 caatactgag aagaagattg cgcaatctat ccgtcctgta aatgtagtca cagatttgca
     6661 tcaaaaacct actcttccaa caacagtaac ggttgagtat gacaaaggtt tccctaaagc
     6721 tcacaaagtc acttggcaag ctattccgaa agaaaaacta gactcctatc aaacatttga
     6781 agtactaggt aaagttgaag gaattgacct tgaagcgcgt gcaaaagtct ctgtagaagg
     6841 tatcgtttca gttgaagaag tcagtgtgac aactccaatc gcagaagcac cacaattacc
     6901 agaaagtgtt cggacatatg attcaaatgg tcacgtttca tcagctaagg ttgcatggga
     6961 tgcgattcgt ccagagcaat acgctaagga aggtgtcttt acagttaatg gtcgcttaga
     7021 aggtactcaa ttaacaacta aacttcatgt tcgcgtatct gctcaaactg agcaaggtgc
     7081 aaacatttct gaccaatgga ccggttcaga attgccactt gcctttgctt cagactcaaa
     7141 tccaagcgac ccagtttcaa atgttaatga caagctcatt tcctacaata accaaccagc
     7201 caatcgttgg acaaactgga atcgtactaa tccagaagct tcagtcggtg tcctattcgg
     7261 agattcaggt attttgagca aacgttcagt tgataactta agcgttggct tccatgaaga
     7321 ccatggagtt ggtgcaccga agtcttatgt gattgagtat tatgttggta agactgtccc
     7381 aacagctcct aaaaacccta gttttgttgg taatgaggac catgtcttta atgattctgc
     7441 caactggaaa ccagttacta atctaaaagc ccctgctcaa ctcaaggctg gagaaatgaa
     7501 ccactttagc tttgataaag ttgaaaccta tgctgttcgt attcgcatgg tgagagcaga
     7561 caacaaacta ggaacgtcta tcacagaggt acaaatcttt gcgaaacaag ttgcggcagc
     7621 caagcaagga caaacaagaa tccaagttga cggtaaagac ttagcaaact tcaaccctga
     7681 tttgacagac tactaccttg agtctgtaga tggaaaagtt acggcagtca cagcaagtgt
     7741 tagcaacaat ggcctcgcta ccgtcgttcc aagcgttcgt gaaggtgagc cggttcgtgt
     7801 catcgcgaaa gctgaaaatg gcgacatctt aggagaatac cgtctgcact tcactaagga
     7861 taagaactta ctttctcata aaccagttgc tgcggttaaa caagctcgct tgctacaagt
     7921 aggtcaagca cttgaattgc cgactaaggt tccagtttac ttcacaggta aagacggcta
     7981 cgaaacaaaa aacctgacag ttgaatggga agaagttcca gcggaaaatc tgataaaagc
     8041 aggtcaattt accgttcgag gccatgtcct tggtagtgat cttgttgctg aggtcactgt
     8101 acgagtgaca gacaaactag gcgaagctct ttcagataac cctaactatg atgaaaacag
     8161 taaccaggcc tttgcttcag caaccaatga tattgacaaa aactctcatg accgcgttga
     8221 ctatctcaat gacggagatc attcagaaaa tcgtcgttgg acaaactggt ctccaacacc
     8281 atcttctaat ccagaagtat cagcgggtgt gatcttccgt gaaaatggta agattgtaga
     8341 acggactgtt gctcaagcca aacttcactt ctttgcagat agtggtacgg atgcaccaac
     8401 taaactcgtt ttagaacgct atgtcggtcc agagtttgaa gtgccaacct actattcaaa
     8461 ctaccaagcc tacgacgcag accatccatt caacaatcca gaaaattggg aagctgtgcc
     8521 ttatcgtgcg gataaagaca tcgcagctgg tgatgaaatc aacgtaacat ttaaagctgt
     8581 caaagccaaa gctatgagat ggcgtatgga gcgtaaagca gataagagcg gtgttgcgat
     8641 gattgagatg accttccttg caccaagtga attgcctcaa gaaagcacgc aatcgaagat
     8701 tcttgtagat ggaaaagaac ttgctgattt cgctgaaaat cgtcaagact atcaaattac
     8761 ctataaaggt caacggccaa aagtctcagt tgaagaaaac aatcaagtag cttcaactgt
     8821 ggtagatagt ggagaagata gccttccagt acttgttcgc ctcgtttcag aaagtggaaa
     8881 acaagtcaag gaataccgta tccagttgac taaggaaaaa ccagtttctg agaagacagt
     8941 tgctgctgta caagaagatc ttccaaaact cgaatttgtt gaaaaagatt tggcctacaa
     9001 gacagttgag aaaaaagatt caacactgta tctaggtgaa actcgtgtag aacaagaagg
     9061 aaaaactggt aaagaacgta tctttacagc gattaatcct gatggaagta aggaagaaaa
     9121 actccgtgaa gtggtagaag ctccgacaga ccgcatcgtc ttggttggaa ccaaaccagt
     9181 agctcaagaa gctaaaaaac cacaagtgtc agaaaaagca gatacaaaac caattgattc
     9241 aagtgaagct agtcaaacta ataaagccca gttaccaaat acaggtagtg cggcaagcca
     9301 agcagcagta gcagcaggtt tagctcttct aggtttgagt gcaggattag tagttactaa
     9361 aggtaaaaaa gaagactaga aattttgata ccttctttat cattaaagac caaagaaaaa
     9421 ctcttgtcct aaatagaaga taaagagtct ggaacaaaat agttctcaac cacaaaaaag
     9481 ctagatattt ccaattgcgg aactctagct ttttaatttt gagtcgttct cttattgtat
     9541 agtagattga aactagagta gtacacttct acttctaaaa cattgttaga aatcgatttg
     9601 actgtcctta tcgatttgtc ctgttcttat ttcatttcac tatgttttag gaggttattg
     9661 gccataagta ccaatcccat gtcaattctc acttgacgct tgcctctcag attacatctc
     9721 ttgtaaccca aacaagcctt tatctgccca aagacaggtt ctacatcaat cttgcgttga
     9781 gcgaaaatct gtctatcttg gggagataaa agcgcctgac attctttagc tttcaagttt
     9841 tgatagcgtt cgttcatata caatcccttt tgaggggctg attcaggttc atcagcgtag
     9901 taaaccttga tttcctgttg aaagtctgtc tgtgttttct ggtacttgat atggtgaaaa
     9961 cgatagcacc agccatcagg atgtatgtag ctatcctcct tgtcattata gtgccaattc
    10021 gctaagtttt tagctgactg tttataccct ctcttttgtt ccttatcaaa catggcatat
    10081 ttaatcagaa ggggagtgat ttcttcttga aaatagactt gtatctgttc ttgaagtttg
    10141 gcggagaatt tctctgtcgt tttcttccac acaaaactat acttgttggc attggattca
    10201 atcttagttc cgtcaataaa caaacaatct aaggtcacta actcttccat ttttcaattt
    10261 ttcgaccaga gaaaatccct tgtgaatagg caaatagaag agtagataca agcattttag
    10321 ggtgataaga cgggcgacca aaggcatgat aggaggtgta gaagtgacgt tcctccaagg
    10381 tattcaccac tttttcaata gtaaagacga gatggtcttg tggtaagaag gaactgattt
    10441 ctagtggtaa agttgtttga tttgtgttat agtgaatatg catgggatag cctttctaaa
    10501 tggtttatta agcaattcta ttttaccaag actatcgtaa ccatgcaaaa aagcaacggc
    10561 aaatccgttg ccttttttgg atataagaga ctattgtccc agactctttt ctttgtataa
    10621 aattgtatag tgttattgtc tatactattt tgtagagaaa gcaaaaatcc ctagaaaatg
    10681 cttagggatt cgactatttc attaagaaca attcaacaat catctctata tacatgataa
    10741 gggttaataa aaatcctgta cgccagaaga atttgatgaa tttaggatag taaaagctgc
    10801 gtttttttaa aaggaagaaa aagacgagaa taatggctag gaacgagagg gctagcccca
    10861 gtctagggag gaaattatgg gtaaaggttt tagctgtaat caagtaatac tcaaatacca
    10921 agactggaaa agccaaatcc gcaaagtttc gtcctagttt ttttaatcta aaaagtttgg
    10981 ttaggataat gcagacgact aaggtcagta tcaataataa aatagatgct aatttcatta
    11041 aaatcatacc catattgtat cataaaaaaa ggctaatgga aacgagaaac agaggaattt
    11101 ataggaaagt caggcttttg agattgtggg tgatttttgt tataatgaaa gttataaaat
    11161 cttatgatac cttgaatgat tattatcgaa aactctttgg agaaaagact tttaaagtcc
    11221 ctattgatgc gggatttgac tgtcccaatc gtgatggaac tgtggctcat ggaggctgta
    11281 ctttttgtac ggtttccggt tctggagatg ccattgtagc cccagatccg cctatccgtg
    11341 agcaatttta taaggaaatt gactttattc atcgtaagtg gccagatgtt cagaagtatc
    11401 tggtttattt tcaaaatttt accaacaccc atgaaaaggt ggaagttatt cgagagcgtt
    11461 atgaacaggc tatcaatgag ccaggtgtgg taggaatcaa tattggaacg cgcccagact
    11521 gtttaccaga cgaaaccatc gaatatttgg ctgagttatc ggagtgcatg catgtgacgg
    11581 ttgaattggg cttgcagact acttatgaag caacctctga cctgattaac cgtgcgcatt
    11641 cttatgaatt gtaggtggaa acggtcaagc gtttgagaaa gtatccaaaa attgagattg
    11701 tttcccattt gatcaatggt ttgcctggtg aaacccatga gatgatggtt gaaaatgtcc
    11761 gccgttgtgt cacggataac gatattcaag ggattaaact gcatttgctc catcttatga
    11821 caaatactcg tatgcaacga gattaccatg agggacgttt acaatcgatg agtcaggacg
    11881 aatatgtcag ggtcatctgt gaccaactgg aaattattcc caaacatatc gtcatccatc
    11941 gaattacagg agatgcgcct agggatatgc tgattggtcc tatgtggagc ctcaataaat
    12001 gggaagtcct caacagcatt gagatggaga tgagacgtcg tggaagtgtt caaggatgca
    12061 aggctgtaaa acaggagttt gaaaatgaaa agaccacttg agatggcaca tgattttttg
    12121 gctgaggtcg tgacaaaaga ggatgtcgta gtggatgcga ctatgggaaa tggtcatgac
    12181 acgctttttt tagccaagct agccaagcaa gtctatgcct ttgatattca gaagcaagcc
    12241 ttggaaaaga cccaagagcg tttgcatcag gctggcttga caaatgccca gttaatcttg
    12301 caaggccatg agacactgga ccagtttgtg acaaaagcta aggcagggat ttttaatttg
    12361 ggctatttgc cgtcagctga taagtctgtc atcacccgac cgcagacaac gattgaggca
    12421 ttagaaaagc tatgtggctt acttgtcaaa ggtggacgaa ttgctattat gatttactat
    12481 ggtcatgaag gaggcgacct cgagagagat gctgtcttgg attttgtgat ccagttgaac
    12541 caacaagagt acacagctgc catttaccga actttaaacc aagtcaacaa cccgccgttt
    12601 ttagtgatga ttgaaaaatt agagagatac agacatggat aaacaatacc tacacgaaaa
    12661 gctggatgcc atgcgccaga attttgttga atcaacctac cacgaacgag cggtgggcgt
    12721 gctagaccaa gcgcatatga gcaaaaaaat gcttaaaatc aagaaaaaat tagttgctct
    12781 tgaaatggaa cggtgccaga gaaaaattga gcacaaagac tgttccaaga ttgaccaaaa
    12841 aatcaaagag cagaaggaga tatttgaatc ctgttgtaaa aaagattaag gaggacgtgc
    12901 gtggaattac tgatttacct catcctattt ttactggtct tgattgtctc aagtacaacc
    12961 aataagctcc tacccttttt gcctctccct ttggtgcaga ttcttttggg aattgtgatt
    13021 ggtctctttt tacccaatac tgactttcac cttaatacgg agttgttttt ggcactggtt
    13081 atcggcccct tgcttttccg agaggctgaa gaagcagatg ttacggctat tttaaaacac
    13141 tggcgaatca ttgtttatct catatttcca gtgattttta tctcgaccct gagtttgggt
    13201 ggcttggccc atcttctttg gttcagcctt cccttggcag cttgcttggc tgttggggca
    13261 gcccttggtc ctacggactt ggtggccttt gcctctcttt cggagcgttt tagctttcct
    13321 aagcgcgtgt ccaatattct taagggcgaa ggactcttga atgatgcttc tggtttggtg
    13381 gcttttcagg tagctttgac agcttggaca actggagctt tttctctggg gcaagctagc
    13441 agttcactca tcttttcaat cctaggcggt tttttaattg gatttttaac agccatgacc
    13501 aaccgcttcc tccatacctt cttgctaagt gtgcgtgcaa cggatattgc cagtgaactt
    13561 ttattagaat tgagtttgcc tcttgtgacc ttctttctgg cagaagaagt tcatgtttca
    13621 ggtattattg ccgtcgtagt tgctggaatt ttaaaggcaa gtcgtttcaa gaaaatcacg
    13681 ctcctcgaag cccaagtgga tacggtgacc gagacggtct ggcatacagt gacctttatg
    13741 ctcaacggtt ctgtctttgt gattttaggg atggagctgg aaatgatagc agaacctatc
    13801 ttgaccaatc caatctataa tcctctactt ttattgctat ctcttatcgc ccttaccttt
    13861 gtcctctttg tcattcgttt tattatgatc tatggctatt atgcctatag aacccgacgc
    13921 ctcaagaaaa agctaaataa gtatatgaag gacatgtttc tcttgacctt ttcaggtgtt
    13981 aagggaacgg tgtcgattgc tacgattctc ttgataccaa gtaatctaga acaggagtat
    14041 cctctcttgc ttttccttgt tgcaggtgtg acgcttgtta gctttttaac aggtctcttg
    14101 gtcttgcctc atctttctga tgaagaggaa gaaagcaagg attatctcat gcatatcgcc
    14161 attttgaatg aagtaacgct agagttggaa aaagagttgg aagacaccag aaataaactt
    14221 tccctctatg cggctattga caattatcat ggacgtattg aaaatctcat tttaagccaa
    14281 gaaaaccagg atgatcaaga agactgggct gctttgaaac tcttgattct tagtattgaa
    14341 agtgatggtt tggaacaggc ctatgaagag gggaatatta gcaatcgtgc ttaccgagtt
    14401 taccaacgtt atctgaaaaa tatagaacaa ggaatcaatc gtaaacttgc ctcaagactg
    14461 acctattatt ttcttgtttc cttgaggatt ttacgttttc tccttcatga agtttttact
    14521 cttggaaaga ccttccgtag ctggaaggac aaggagcaaa gccgtctccg tgctcttgat
    14581 tatgaccaaa ttgcagagct ctatcttgcc aatacagaga tgattattga aagtttggaa
    14641 aacctgaagg gagtctacag acgctctttg attagtttta tgcaggagtc tcgtcttcga
    14701 gaaacagcta ttatcagcag tggtgccttt gtcgaacggg ttatcaatcg tgtcaaaccc
    14761 aacaatatcg atgaaatgct gagaggctat tatctggagc gcaagttgat tttcgaatac
    14821 gaagaaaaac gattaattac aactaagtat gccaagaaat tacgacaaaa tgtaaataac
    14881 ttagagaact attccttgaa ggaagctgcc aataccctgc cgtatgatat ggtggaattg
    14941 gtaagaagaa attagttaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt
    15001 ggattatata tgtgactgac ttcgtcagtt tcatctacaa cctcaaagca gggctttgag
    15061 caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa gattataaat
    15121 gaaggagtat gacatgaaaa agtggtggaa agagctgata gacaagcctt tattaaaagc
    15181 ttttttgcat tattatcaag catcagatag tgagttgacc agtgtcgcag tagcctacta
    15241 ttggttgatt tcgattttcc ccctgctttt ggtggtggtc aatatcctcc cctattttca
    15301 gattcctgtg ggagaatttc tgtgctttat gaaagacgtt ctgcccccaa gcctctatga
    15361 aggtgtggaa aaaatagcca gagaagtttt gacgcaacct tcaacaggtt tattgagttt
    15421 ttctgtttta tcggcgttat ggagtttttc aaaatctatg aatttcttgc aaaaagcttt
    15481 taacaaggct tatggcgtcg aaaagagtcg tggacttatt tcccatcaga tgctaagtct
    15541 cctagtcagt tttggcttgc agctcctctt tgcgtttgcc ttgtttttga tcttatttgg
    15601 tcagatgatt ttggctttac ttgctcatta ttggacaaaa gatggcatta tctatcaggc
    15661 tttacaaggg ttggcaggtc ctctgattta cgccctcctc tttgctatct tggtcatgct
    15721 ttattatttt cttcccaata tatctaacag gaaaattagc tataccctac caggcagtgc
    15781 ctttgttctc ttagtgattt taggtttact aactctgttc tctagttatc tcaattacta
    15841 tgtccatcat ttggtggatg tccgaatttt aggttccgtt cttcttgttg ttatgatgtt
    15901 ttggtttatc ttgattgcta aaattgttat cctaggcgcg gttatcaatg ccagtatgca
    15961 gagtttgaga gatccggtct ttaaaaaaga ctaactattt atccattaca aaagcgcata
    16021 gtatcaaaac tttatagaac cttgatacta tgcgcttttg tgctttgaca gttttttgta
    16081 tagtttttgt ccaagatttc taaatcatct gattaaattc ctattttccc ctatcattgt
    16141 ccctgttttt tcgaaaatgg aaggagtata ataaatctat caataaaatg ataggaggaa
    16201 ctttatgggt catattttct tttttctaag tgtctttttg gcagggattc tatccttctt
    16261 ttctccttgt atcttacctt tgttaccggt ctatacagga gtgttactag atgataagga
    16321 tggtgctcag gcttctagcg gcaaattttc aatctcagtt actagtttat tacgaactct
    16381 ggcctttata gcaggaattt cctttatatt tattttgttg ggctatggag ctggtttttt
    16441 aggcgatttg ctttatgctt cttggttcca atatcttact ggggcaatta ttatccttct
    16501 tggtttgcac caaatggaga ttctacactt taaggggctt tataaggaaa agaggctaca
    16561 actgcaagga caggggcaaa atggtaaggg ctatagtcag gcatttttat tgggcttgac
    16621 ctttagtttt gcttggacgc cttgcgtggg gccggttctg gggtctgttt tggccttggc
    16681 ggcttcaggt ggttcaggag cttggcaggg agctggtctc atgttggtgt atacgctggg
    16741 cttggcgcta ccattcttgc ttctagctct gacctctagt tatgttttga aacatttccg
    16801 aaaacttcat ccctatctcg gaatcctcaa aaaagtgggt ggttttctca ttattgtgat
    16861 gggactcttg gttctgtttg gaaatgcttc aattttaagt caattatttg aataaaatgg
    16921 aaaggaatat caatatgaaa aaatggcaaa catgtgttct tggagcaggt tcgctccttt
    16981 gtttgacggc ttgttcaggc aagtccgtga ctagtgaaca ccaaacgaaa gatgaaatga
    17041 agacggagca gacagctagt aaaacaagcg cagctaaagg gaaagaggtg gctgattttg
    17101 aattgatggg agtagatggc aagacctacc gtttatctga ttacaagggc aagaaagtct
    17161 atctcaaatt ctgggcttct tggtgttcca tctgtctggc tagtcttcca gatacggatg
    17221 agattgctaa agaagctggt gatgactatg tggtcttgac agtagtgtca ccaggacata
    17281 agggagagca atctgaagcg gactttaaga attggtataa gggattggat tataaaaatc
    17341 tcccagtcct agttgaccca tcaggcaaac ttttggaaac ttatggtgtc cgttcttacc
    17401 caacccaagc ctttatagac aaagaaggca agctggtcaa aacacatcca ggattcatgg
    17461 aaaaagatgc aattttgcaa actttgaagg aattagccta ggaggtgtct tatgaatgat
    17521 aagttaaaaa tcttcttgtt gctaggagta ttttttctag ccataaccgg tttctatgtt
    17581 ctattgatac gaaatgcagg gcagacagat gcctcgcaaa ttgaaaaggc ggcagttagc
    17641 caaggaggaa aagcagtgaa aaaaacagaa attagtgaag acgcagactt gcacgaaatt
    17701 tatctagctg gaggttgttt ctggggagtg gaggaatatt tctcacgcgt tcccggggtg
    17761 acggatgccg tttcaggcta tgcaaatggt agaggagaaa caaccaagta cgaattaatt
    17821 aaccaaacag gtcatgcaga aaccgtccat gtcacctatg atgccaagca aatttctctc
    17881 aaggaaatcc tgcttcacta tttccgcatt atcaatccaa ccagcaaaaa taaacaagga
    17941 aatgatgtgg ggacccagta ccgtactggt gtttattaca cagatgacaa ggatttggaa
    18001 gtgattaacc aagtctttga tgaggtggct aagaaatacg atcaacctct agcagttgaa
    18061 aaggaaaact tgaagaattt tgtggtggct gaggattacc atcaagacta tctcaagaaa
    18121 aatccaaatg gttactgcca tatcaatgtt aatcaggcgg cctatcctgt cattgatgcc
    18181 agcaaatatc caaaaccaag tgatgaggaa ttgaaaaaga ccctgtcacc tgaggagtat
    18241 gcagttaccc aggaaaatca aacagaacga gctttctcaa accgttactg ggataaattt
    18301 gaatccggta tctatgtgga tatagcaact ggggaacctc tcttttcatc aaaagacaaa
    18361 tttgagtctg gttgtggctg gcctagtttt acccaaccca tcagtccaga tgttgtcacc
    18421 tacaaggaag ataagtccta caatatgacg cgtatggaag tgcggagccg agtaggagat
    18481 tctcaccttg ggcatgtctt tacggatggt ccacaggaca agggcggctt acgttactgt
    18541 atcaatagcc tctctatccg ctttattccc aaagaccaaa tggaagaaaa aggctacgct
    18601 tatttactag attatgttga ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc
    18661 gccttaccgt atgtagggtt actgacttcg tcagttttat ctacaacctc aaagctatac
    18721 tttgagctga cttcgtcagt tttatctaca acctcaaagc ggtactttga gaaacctgtg
    18781 gctatcttcc tagtttactt tttgattttt attgagtata agaggtcttt cctaagcagt
    18841 tagaggagaa ttttgctata ctgatactag taagtggtaa aggagcagag catgacctac
    18901 acaatcttaa tcgtagaaga tgaatatctg gtaagacaag gtttgactaa actggtcaat
    18961 gtagcagcct acgatatgga aatcatcggt caggctgaaa atggaaggca ggcttgggaa
    19021 ttgatccaaa agcaggtgcc agatatcatt ttaaccgata tcaacatgcc tcatctaaat
    19081 ggcatccagt tggccagtct ggtacgagaa acctatcctc aggttcattt ggtcttttta
    19141 acaggttacg atgattttga ttatgccttg tctgctgtca aactaggtgt ggacgactac
    19201 ctgctcaaac ccttttctcg tcaggatatt gaggaaatgt tggggaaaat caaacaaaaa
    19261 ctagacaagg aagagaaaga agagcagtta caagatttat tgactaatag gtttgaagga
    19321 aacatggccc agaaaatcca gtctcatctg gctgatagcc aatttagttt aaagtcttta
    19381 gccagtgact taggttttag tccgacctat ctgagttcct tgattaagaa agagttgggc
    19441 ttgccttttc aggattatct ggtgagagaa cgtgttaaac aagccaagct cttgctttta
    19501 actacagatc tgaagattta tgagatcgca gagaaggttg gttttgaaga tatgaactat
    19561 tttacccaac gttttaagca gattgcaggt gtgacacctc gtcagtttaa gaagggagaa
    19621 gaccgatgaa gcgttcttct cttttagtta gaatggttat ttccatcttt ctggtctttc
    19681 tcattctcct agctctggtt ggaactttct actatcaatc aagttcttca gccattgagg
    19741 ccaccattga gggcaacagc caaacgacca tcagccagac tagccacttt attcagtctt
    19801 atatcaaaaa actagaaacc acctcgactg gtttgaccca gcagacggat gttctggcct
    19861 atgctgagaa tcccagtcaa gacaaggtcg agggaatccg agatttgttt ttgaccatct
    19921 tgaagtcaga taaggacttg aaaactgttg tgctggtgac caaatctggt caggtcattt
    19981 ctacagatga cagtgtgcag atgaaaactt cctctgatat gatggctgag gattggtacc
    20041 aaaaggccat tcatcaggga gctatgcctg ttttgactcc agctcgtaaa tcagatagtc
    20101 agtgggtcat ttctgtcact caagaacttg ttgatgcaaa gggagccaat cttggtgtgc
    20161 ttcgtttgga tatttcttat gaaactctgg aagcctatct caatcaactc cagttggggc
    20221 agcagggctt tgccttcatt atcaatgaaa accatgaatt tgtctaccat cctcaacaca
    20281 cagtttatag ttcgtctagc aaaatggagg ctatgaaacc ctacatcgat acaggtcagg
    20341 gttatactcc tggtcacaaa tcctacgtca gtcaagagaa gattgcagga actgattgga
    20401 cggtgcttgg cgtgtcatca ttggaaaagt tagaccaggt tcggagtcag ctcttgtgga
    20461 ccttgcttgg ggccagtgtc acatctcttc ttgtctgtct ctgcttagtg tggttcagtc
    20521 ttaaacgctg gattgctcct ttgaaggatt tgagagaaac catgttggaa attgcttctg
    20581 gtgctcaaaa tcttcgtgcc aaggaagttg gtgcctatga actgagagaa gtaactcgcc
    20641 aatttaatgc tatgttggat cagattgatc agttgatggt agctattcgt agccaggaag
    20701 aaacgacccg tcagtaccaa cttcaagccc tttcgagcca gattaatcca catttcctct
    20761 ataacacttt ggacaccatc atctggatgg ctgaatttca tgatagtcag cgagtggtgc
    20821 aggtgaccaa gtccttggca acctatttcc gcttggcgct caatcaaggc aaggacttga
    20881 tttgtctctc tgacgaaatc aatcatgtcc gccagtatct ctttatccag aaacaacgct
    20941 atggagataa gctggaatac gaaattaatg aaaatgttgc ctttgataat ttagtcttac
    21001 ccaagctggt cctacaaccc cttgtagaaa atgctcttta ccatggcatt aaggaaaagg
    21061 aaggtcaggg ccatattaaa ctttctgtcc agaaacagga ttcgggattg gtcatccgta
    21121 ttgaggatga tggcgttggc ttccaagatg ctggtgatag tagtcaaagt caactcaaac
    21181 gtgggggagt tggtcttcaa aatgtcgatc aacggctcaa acttcatttt ggagccaatt
    21241 accatatgaa gattgattct agaccccaaa aagggacgaa agttgaaata tatataaata
    21301 gaatagaaac tagctaactc ccagtcaatt ctgggagttt tatgcgtaat tgggcaaact
    21361 ttctaggttg tctatcttgc taaaaacaag aaaaaacggt atgatagaag agtgacaaca
    21421 gaggtaacag agatgaacga gacacagatt caaagagaaa cacgtcaggt agtggaagat
    21481 gttttagaaa agaccaattt gaagcagggg gccctttttg ttttaggtct atcttctagt
    21541 gaggtgctag gtggtcatat tgggaaagaa tccagtcaag agattggtga gctgatagtg
    21601 gagactatct tggatattct aggtagtaga ggtatccatt tagcagttca aggttgtgag
    21661 catgtcaatc gggctctcgt tgttgaacgt caggtggcag agcagtttgg tctggaaatt
    21721 gtcagtgtcc atcctactct tcatgcagga ggttcggggc agttggcagc ctttaagttt
    21781 atgcaggatc cagttgaggt tgaatttatc aaggctcatg ctggattgga tatcggagac
    21841 actgcaattg gcatgcatgt caagcatgtt caggttccga ttcgccctat tttgagagag
    21901 attggtcatg cccatgtaac ggcactggct agtcgtccaa aattaatcgg aggtgcgcgt
    21961 gcgcactatc cgcaagatgc tattagaaag acctgagaat gaataaagga gataaaagtg
    22021 tttaaaaaag accgtttttc aattcgtaag attaagggag ttgtaggctc tgtatttctt
    22081 ggaagccttt tgatggctcc ttctgtagtg gacgcagcca cctatcacta tgtaaataaa
    22141 gagattattt cacaagaagc taaagattta attcagacag gaaagcctga caggaatgaa
    22201 gttgtatatg gtttggtgta tcaaaaagat cagttgcctc aaacagggac agaagcatct
    22261 gttttgacag cttttggtta tctatcaggt gacatcctca aaacgcttgg cttggacact
    22321 gttttagaag aaacctcagc aaaacctgga gaggtgactg tagtcgaagt tgagactcct
    22381 caatcaacaa caaatcagga gcaagctagg acagaaaacc aagtagtaga gacagaggaa
    22441 gctctaaaag aagaagcacc taaaacagaa gaaagtccaa aggaagaacc aaaatcggag
    22501 ataaaaccta ctgacgacac ccttcctaaa gtagaagagg ggaaagaaga ttcagcagaa
    22561 ccagctccag ttgaagaagt aggtggagaa gttgagtcaa aaccagagga aaaagtagca
    22621 gttaagccag aaagtcaacc atcagacaaa ccaacagagg aaccaaaagt tgaacaagta
    22681 ggtgaaccag tcgagccaag tgaagacgaa caggcaccaa cggcaccagt tgagccagaa
    22741 aagcaaccag aagctcctga agaagagaag gctgtagagg aaacaccgaa accagaagat
    22801 aaaataaagg gtattggtac taaagaacca gttgataaaa gtgagttaaa taatcaaatt
    22861 gataaagcta gttcagtttc tcctactgat tattctacag caagttacaa tgatcttgga
    22921 cctgttttag aaactgcaaa aggtgtctat gcttcagagc ctgtaaaaca gcctgaggta
    22981 aatagtgaga caaataaact taaaacggct attgacgctc taaacgttga taaaactgaa
    23041 ttaaacaata cgattgcaga tgcaaaaaca aaggtaaaag aacattacag tgatagaagt
    23101 tggcaaaacc tccaaactgg ggttacagaa gctgaaaaag ttgcagctaa tacagatgct
    23161 aaacaaagtg aagtaaattc tgagactgca agtcttaaaa cagcaatttc tagattaaat
    23221 acagataaag ttgaactcga aaatcaactt aagattgcac agggaaaaac tgaaactgat
    23281 ttcagcatgg aatcttggac tgttttgagt acagctaaaa ataaagctca ggaagtaaaa
    23341 gataacggaa cagcgaccca agaacaaata aacgaagcag agaaaagttt gaaaacagcc
    23401 cttgctgact tatctgttga caaaacagct ttgggaagcg ctatcgatac agctactaag
    23461 aaaaataaag agaattatac aaatcaaaca tgggcagagt tggaaacagc gcttacagca
    23521 gcaaaatctg taaatactaa cgagtctaaa caaagcgacg ttaacgaagc tgctgaaaaa
    23581 ttaactgcaa ctatggaaaa attggttgaa ttgtctgaaa agccacgttt gactctatct
    23641 attgaaaaga gagacataga tcgaaaagct acggtcacgt atactttgga aaatccagca
    23701 aatactcaaa taaaatcaat aactgcaact ctgaaaaaag gagaggaagt tgttaaggat
    23761 tttgttttaa cagaagaaaa tcttaaaact aatcatttaa ctgctttgtt tgaaaagcta
    23821 gactactaca aagaatacac tctatctacg gatatggtat ataacagagg aaatgatgat
    23881 gagacggaga gtatttcaga agaactaatt cagctgaatc ttaagaaact agaattgaaa
    23941 gatatccaga cagtctctct gatgaaattt gaaaatggtc aagaaagtca ggttacacac
    24001 ttgtctgata aaccgaccga tttgagtaaa ttatacttaa aagttacatc atcaacgtct
    24061 aaggatgctg tgttagccgt tagctctata gaagaagaga ttattgaaaa taaaaaaatc
    24121 tttaaaattc atgcagatac accagaatta gtagttcgta agaaagatgg cagtctttct
    24181 aagggatttg actattacat ggagagagtt atccctcatg atggtgatat ttattatgat
    24241 tttaaagact tgatttcagc tatgacatct aatcctacag gtacgtttat tttagggaga
    24301 gatatttcct cgcgtaatgt aaaaccggat ggaaatggaa aatcttatat caaaggtgaa
    24361 tttaaaggaa aactacttgg tacaaatgat aatgttagac actcgatctt tgacttagaa
    24421 tatccattgt ttgatactat aaaatcagga gtcgtgaaag atattgattt caagcatgtc
    24481 aatatggtat tcccagatag caatcaagga gataacgtag caacaattgc aagagtaatc
    24541 aaagataaga caaaaattga gaatgttaat gttgaaggtt atctcgaggg tcgagatcat
    24601 gtagctggtt tagttaataa tcttgaaggt aattccgaaa ttgaaaatgt atcctttaca
    24661 ggaaagatta agtctaaagg tggtaattct attacagcag gtattgcagg tagaaatatc
    24721 ttatctcgtg ttaaacgtgc ctatgtaaat gcagatatag aggtacatcg atcatctaat
    24781 tctagcatgc ttgttgcagt aaatggaata aacgcagatg caagtggtgg ttggggaacc
    24841 tggggtagac ttactgagtc agttgctaaa ggaacattag aaaccaagca aggagggcaa
    24901 gctggaggag cctcttctac agtctggcct tatggagcaa ttgataatgt tgtcagctat
    24961 gcaaaagtga ccaaagggaa agaattattt ggatcagatg gtgatttaaa ttatgattgg
    25021 tttatgaaaa aaattagtaa tatttttggt gttcaaggca tcagctcagg cgattcgggt
    25081 agtgattcta aatttacgcg tatttctgag gaagaagcaa atcaaaaagt tgcttcttat
    25141 aatattacag ctcccaactt gatgagtgac tcaagtcttt tggtagacag actcaatgaa
    25201 agttggaaaa atactgatca atttgaaagt atacaggatt atcaagccca aaaccaatta
    25261 atttaccaga acttgactaa atttactcct tattacaata aagaatttat tgttcatgaa
    25321 ggaaatgctc tcactcctga acaggaaata ttgaagacta agaaaatcaa atcgattgta
    25381 gggttgaaag gaacagagtt cgttgtagat ggcagtgata ttgatactat catgcttcat
    25441 tttgaggatg gtagtcagaa gcgatataag gtaacctcta ctggtaagtt ttcgataact
    25501 aatttaccgg aatatcaggt tgaagattta aatgtggtgt atacatcaga acatatagta
    25561 catccactag attcgtcact gataaataac cttgttgaag aattgaaaaa agtagaattg
    25621 tatacagagt ctacttacca agttctaggt attgataaag ataatgctaa caaattgaat
    25681 agaactaaga gattattctt agatgagtca ttagatgctg ttaaaacaca attgcctacc
    25741 tttgtaaaaa caatgtttga aaatgagtgg ttgcacatca atggagaatc tagtggagct
    25801 gtcgctgctt tacgacaaaa aatcatggat aataagacgg ctatattgct tgctttgact
    25861 tatatcaatc gttattatga tgttaaattc tcagactata atattaaaaa actgatgctc
    25921 tttaaaccaa ctttccatgg tgaaaagatt gatctattag atcgattaat ccgactagga
    25981 tcatctggag aaaatagatt aaaaggttca gaaaatgcag aaacgttcaa gcagttattt
    26041 gctagcgaaa cgaagcagaa ggatttggtg acttatttag actacaatcg ctctttgttg
    26101 actaattatc aaacaacagg ggaatggttt aaagaaacga ctaaggatta tattcaattt
    26161 gaggaacgtc catccttagt agaggagatt aaagatgcca aatatcgagt ttacgataat
    26221 ttaaccgcac cgtattatca aggatatatc ctacctctct taacgttgaa gaatactcat
    26281 ttagcaattt tatcgaacta tagtactatg acatttgtca gccgtgaaaa acgccctaat
    26341 tggaaaaatg aagattttga taagtgggtg aaatatgtag caactgctca tagaaaccat
    26401 gttgatactt ggtataagat tttacctgat aatatcaaag gtaaaatggt taaagagaat
    26461 gttactgctg tttgggaagg attgagcatc ccaggaagtg aatgggtaga ccagaatgct
    26521 gtagatagaa aaggaagaga ttacgcccca gctcgagaat tctttaatct tgtaggtggt
    26581 cctatgggag gttggtatgc ttaccatggt tatggtgcgc atgctggagg aagaaatcgg
    26641 gttaattatg aggtgtttga tgtattaagt gagtatggta tatcggtctt tactcatgaa
    26701 ttgactcacg ttaatgatac ttggatttac ttaggagggt atggtagacg tgaaaatatg
    26761 ggacctgaag cttatgctca gggattattc cagtctcctg ttccaggtca gccgggttgg
    26821 ggggcgcttg gtctcaatat ggcatttgaa agaaaaaatg atggtgatct aatttataat
    26881 gcctccccaa ctcaatttga aaataggaaa gagttagata gttatatgaa aaattataac
    26941 gatactctca tgatggtgga ctacttggaa ggagatgcag ttatctctaa aggtaaagaa
    27001 gctattacta aatggtttaa aaaagttgaa cctaaggttg ttagtcaaac agctcagtat
    27061 gatacggttc gtcagttgac tgctgaagag aaagaaaaac tttctgtttc tagtgttgat
    27121 gatttagttg atcaaggatt aatgtcagac agagctgtag gaaataatac ctataatcca
    27181 gctgattttg aaacaagtta tattgcgata gattatatga ctggtattta tggtggagga
    27241 aagaatagtg taggttcacc aggtgccttg atgtttaaac ataatacttt ccgtatgtgg
    27301 ggctactatg gttttgaaga aggtgttcta ggatatgctt ctaataaatt taagcaagca
    27361 tctagagatg aaggtcatgc tggacttagt gataacttta ttatttctaa gatttccaaa
    27421 ggggaatttt taactatgga agcatttaaa aagggatatt ttaagaaagt agtagaagag
    27481 ttaaaaacta aaggtattcg tcctgttact atcaatcaaa aaacatatag cacctttgaa
    27541 gaattgcaag aaggatttaa gcaggctgtt gaaagagatt tgaagaaaaa tcagttagat
    27601 gagagggaaa caagaaactt caaattccaa gttttcagac aacttcttca acaaacagat
    27661 agctttaaaa cttctatctt tagataatcg aaatctctca tctgctttgc ggatgagggt
    27721 tttcttattt tatgctatac ttaaagtatg catagaaaaa cagtgattga ttttaggact
    27781 ttgggggaga gatatacctt tacccagcct attaaagagt tgaaaacgag aaatgtagaa
    27841 gaagtggcag atttgctggc acaagtggaa agctaccaag agcaaggtta ttatgtggtg
    27901 gggtatgtca gctacgaggc tgcacctgct tttgaggaaa aattagcagt tcacaaggat
    27961 cccctactgg gagagtacct gctttatttt actgttcatg atagcgtaga aacttcccct
    28021 attcctctga cttatgagga tattgatttg ccctcaaatt ggcaggaagt aacgtctgca
    28081 gcagactatg aaaaggccat tgcccaaatt caccatcatt tacggcaggg agatacctat
    28141 caggtcaact acaccgtcca acttaagcaa aagttaaatg ccaatccttt tgccatctac
    28201 aatcgtatgg tggtagagca ggaggcgggc tacaatgcct atgtggaaca tgacgagatg
    28261 gcagtgattt ccatgagccc agagctcttt tttgagcaaa atgatcgcga gttgacaaca
    28321 cgaccaatga aggggacgac tcagcgtggg gtaactgacc aagaagatct tgaacaggcc
    28381 agttggttgg aacaggatcc caaaaatcgc tctgaaaata tgatgattgt ggacctcttg
    28441 cgcaatgata tgaaccgtat ttctgaagtt gggagcgagc acgtggagcg tctgtgtcag
    28501 gtagagcagt attcaactgt ttggcagatg acttcgacca tcaagagtca gttgcgagag
    28561 gatgtggacc ttgttgaaat cttccactca ctctttcctt gtggttccat aacgggtgca
    28621 ccgaaaattg cgacaatgga gattatcaag gacttggagc ctcaaccgcg tggagtctac
    28681 tgtggaacga ttggtctctt gcttccaaat ggacgacgga tttttaatgt ggccattcgt
    28741 accattcaac ttcacaaagg tcaagccatt tatggagttg gcggagggat tacttgggat
    28801 agcacttggg aatctgaata ccgtgaagtt catcaaaagg cagcagttct ctatcgtaaa
    28861 caagctcgct tccaattaat tacaactgga aaaatcagcc aaaaacaact gatgtttgaa
    28921 gaacaacatc tggaaaggct gagaaaagct agtcggtatt ttgcttatcc ttttgaccca
    28981 gaaattttga gacaaaagat tgaagcagag tgtcagactt gtgatgctaa tcaagattac
    29041 cgcttgcgaa tttctctcag caagtctgga gagatagaat tcagtcgtca aatcttaaca
    29101 cctcttagtc caagtttttg tcaggccaaa ctttgtctgc aagaagcgaa tttgaatcaa
    29161 tcctttacct attttaaaac gacttacaga ccgcatttga gcatagagga acaagagaag
    29221 atttaccata atggaaaagg agaacttctt gaaacctcta tcggaaattt ggttctgaaa
    29281 atcgatggga aactctacac accgcctatc cgacttggaa tcttgccagg aatttatcac
    29341 cagtatttac tagaaacagg acaggtagaa gagaaagtct tgaccttggc agattttgcc
    29401 caagcagaag ctatttacgg ctgtaatgca gtgagaggct tgtatgagtt gcaagtgata
    29461 ggattgtgag ttttagctat taatagtttt taatatatat taaaatatat tggtgtttac
    29521 ttttgatgag atatcatatt tgtgttataa tgtaaccgta aacaatagaa atttaaagga
    29581 gatttttgat gaaatcaaaa atagttttgg gagcttcgct agcgatcgca acacttagct
    29641 tagtatctct tgtcgagatt gaaggactct caccgttttt aatagagaat gttagcgcaa
    29701 atactcattc tgcaaataaa gttattaatc ataaagtaag tatttactta gaaaatgctg
    29761 atgaaggtaa aggtctaact gtaaactttt caacagacag tgttagtcca aatttatttg
    29821 atgagttcga aaaaaagagt ggaattacaa taactactat gttagtgaat gctaagacag
    29881 gtgaagttgt agaaaaaaga ttaacaccaa gcgttttttt acgttccaat gatttaacca
    29941 gtgggaccat atcttcgttt atttttagtg aatatcctga tggagaatat aaatatgttg
    30001 tgtctaaagg agactttatc gatcctaaga ctcagtttaa acatcagtat agaggagaat
    30061 ctccagtttt tagaatacgt aatcgaaaat atgtggagtt gggaacaact gataaaaaat
    30121 tagatgaaag acgtgataat agcgtttata aagatggggt tgttgaacac aaggtaaatt
    30181 taagtttaac aagttatcaa ggaggtaatg gagttactgc aattttttca actgatagtg
    30241 ttaactctaa cttacttaat tcttttggtg aaaaggctaa aaaagttttg attaggtcta
    30301 agttaattaa tgttaagact ggcgaggtta ttgatgaaac gttttctcca aaagtaagtt
    30361 taacctctaa aattttgaaa agtggttcta cagcagtatt ttattttata gatttaactg
    30421 atggcgaata taaatatgtt gcgtatgaaa gccagcaata tactgatcct caaacaacat
    30481 tgactcatca gtatagagga gaatctccta tttttagtat caaagatgga aaattttctg
    30541 gtttagtatc tgcctcaaaa ccagacgaaa acccgaagcc aacgccaaaa ccggatgaga
    30601 aaccaaaacc ttcagcacca caacaggaga aaacaaaacc tacagttcag tctggttggg
    30661 taggttcatc ttattatcaa aatggtaaaa aagtcactag taagtggatt tttgataaaa
    30721 aatataattc atacttctat ctagatgcat caggaaatta tgttcaaaac gcttgggtag
    30781 gtaactatta tctcaaatca ggcggataca tggctaaaag tgagtggatt tatgataaga
    30841 actatggttc atactactat ctaacatcag aaggcagcta cgctcgtaac acttggtcag
    30901 gcaattatta tttgaagtca aatggtaaga tggctaaaag tgagtgggta tacgatagta
    30961 actacaaatc atattactac ttgacatcag aaggaagtta tgctcgtaac acttgggtag
    31021 gcaattacta tcttaaatca aacggtaaaa tggctgttaa tgaacgtaca ccagatggtt
    31081 atcgtgtaga tggttcaggt aaatgggtta aataagaaac taaaaaatag gataataggt
    31141 aatatcagat gaataaaaaa aattattttc atgtgcttta gcattttcaa cgattggaac
    31201 attgtcaacg attgataaat caggagttct tcctttttca gcgcaaacgg tgcaggctga
    31261 catacaaacg cttaccccaa tggcaaaata ttatattatt cttccgaagg atgcagaaat
    31321 atataaaact tggagaggta ctgtcaatat tcccattatt gatgctacaa aaactactcc
    31381 agaattatct tatttcaaag aagatcatcg caactatata gctaatgaga ataagtctgg
    31441 tgccaattac atagagtgga agggaacagt agaagagttt aaagaggcca ttaagaagtt
    31501 gactgataaa aaatcaacta ctgcaacacc aaaaaaggat gaaaagccaa caccaaaacc
    31561 ggatgagaag ccaaaaccaa cacctacagt tcagtctggt tgggtaggtt catcctatta
    31621 tcaagatggt aaaaaagtca ttagtaagtg gatttttgat aaaaaatata attcatactt
    31681 ctatctagat gcatcaggaa attatgttca aaacgcttgg gtaggtaact attatcttaa
    31741 atcaggcgga tacatggcta aaggtgaatg ggtttatgat gccacctatc aagcttggta
    31801 ttatttgaca tcagatggtt cttatgctta cagtacatgg caaggaaatt actatctaaa
    31861 atcggatggt aaaatggctg tcaatgaatg ggttgatggt ggacgttatt atgttggcgc
    31921 tgacggagtt tggaaggaag gtcaagcaag tacagcttct tctagtaatg atagcaatag
    31981 tgaatattct gctgctttag gaaaggcaaa aagttataat tcgttattcc acatgtcaaa
    32041 aaaaaacgta tgtatagaca attaacttct gattttgata aattttcaaa tgatgcagct
    32101 caatatgcca ttgatcatta gatgattaac agatactggt aggcgaaaaa attccttata
    32161 atccatttac gcaaaccttt gcataagtga atggattttg atatactagt actgtaagca
    32221 ttttcaatta ctacacaatg aaaaaggaga atatgatgag tcaaaagatt attgggattg
    32281 accttggtgg aacttctatc aaatttgcaa tcttaacaac agcaggagaa atccaaggaa
    32341 aatggtcaat caagaccaac attttggatg agggaagtca tatcgttgat gatatgattg
    32401 agtctattca acatcgtttg gacttgcttg gattggcagc agcggacttc caaggcattg
    32461 gaatgggatc accaggtgtg gttgaccgtg acaaagggac tgttatcggt gcctacaact
    32521 tgaactggaa aacccttcaa ccaatcaaac aaaagattga aaaagctttg ggcattccat
    32581 ttttcatcga taatgatgcc aacgtagcag ctcttggtga gcgctggatg ggtgctggag
    32641 ataaccaacc agacgttgtc tttatgacac tcggtactgg tgttggtggc ggtatcgtcg
    32701 cagaaggcaa attgcttcac ggtgttgctg gtgcagcagg tgagcttggt cacatcactg
    32761 ttgactttga ccagccaatc tcatgtactt gcggtaagaa aggctgcctt gagacagttg
    32821 cttcagcaac agggattgtc aacttgactc gtcgctatgc cgatgaatac gaaggcgatg
    32881 cagccttgaa acgcttgatt gataatggag aagaagtaac tgctaagact gtctttgatc
    32941 tcgcaaaaga aggagacgac cttgctttga ttgtttaccg taacttctca cgttacttgg
    33001 gaatcgcttg tgctaacatt ggttcaatcc taaacccatc aacaatcgtc atcggtggtg
    33061 gtgtgtcagc tgcgggagaa ttccttctac aaggtgttca aaaagtttac gatgaaaata
    33121 gtttcccaca agtacgcaca tctactaaat tagctcttgc aactctagga aatgacgctg
    33181 gagttatcgg agcagcatca cttgtattgc aataagataa tgagagagga aaatgctaac
    33241 ctagagttag taatgttcct cttttatttt ttatgctata ctagttagga caatgaatga
    33301 ggtgagagta aatgacaaaa gcagatacga tttttaaaga gaatattgaa tgcattctaa
    33361 aggaaggtgt tttctcagag caagctcgtc ctaagtacaa ggatgggact gttgctaatt
    33421 ccaagtatgt aactggtgcc ttttccgagt acgacttatc taaaggagaa tttcctatca
    33481 caaccttgcg tcccattgca atcaaatccg ccatcaaaga agttctctgg atttaccaag
    33541 accagtcaaa tagcttagaa gtgcttaatg acaagtacaa tgttcactac tggaatgact
    33601 gggaagttgg agacacggga accattggtg agcgctatgg tgccgttgtt aagaaacacg
    33661 acattatcaa taagcttctc aaacagttgg aaaccaatcc ttggaatcgc cgcaatatta
    33721 tttcgctctg ggattaccaa gctttcgaag aaacagatgg gctgctcccg tgcgcctttc
    33781 agaccatgtt tgatgtccgg cgtgttgatg gggaaatcta tctggatgcg accttgaccc
    33841 agcgctccaa tgatatgctg gtggcccacc acatcaacgc tatgcagtat gtggctttac
    33901 agatgatgat tgccaaacat tttggttgga aggttgggaa gttcttctat ttcatcaaca
    33961 acctccatat ctatgataat caatttgaac aagctcagga attgctccgt cgggagccgt
    34021 caaactgcca accacgcttg gttttaaatg ttcctgatgg gactaatttc tttgatatca
    34081 aagcagaaga ttttgagttg gtggattatg accctgttaa gccacagttg aagtttgacc
    34141 tagctattta aaagaataga aaaaagaagt tgagaataat cccaacttct tttgtttctt
    34201 aacgtgatac gcggcgacga gctgcttttt tacgattttc ttcgatgaaa gctgcttttt
    34261 gctcttctgg ttcgattact ttctttttaa atgcgtatac tgcacctgca acggcagcga
    34321 cagttcctgc gacacctgtt acaagacctt tagcgaatcc tttagccatg agtcttcctc
    34381 ctttatattc tcaatcagcc agcctcctca agaggtcaca tttttctgac tgaccttttt
    34441 gtgttataat aatagtaacg aaaaaatggg aatttttcaa ggaaaaaaga tgaaaacaaa
    34501 aataattgtg attgttggac cgactgctgt tggaaagacg gctctagcta ttgaagttgc
    34561 aaagcgcttt aatggcgaag tggttagtgg agatagccag caagtctatc gaggacttga
    34621 tattgggacg gccaaggcta gtccagaaga gcaggcagct gttcctcatc atttaatcga
    34681 tgttagagag ataaccgagt cttactcggc ttttgatttt gtttcagaag ctaagatgac
    34741 tattgaggat attcagagcc gtggcaagct agccattatc gccggtggga ctggacttta
    34801 tatccagagc ttgctagaag gttaccacct aggtggggag actcctcatg aggagatttt
    34861 agcttatcga gctagtttgg agccatattc agatgaggaa ttagcccatt tggtggagca
    34921 agcaggcctt gagattcccc agtttaatcg tcgtcgtgct atgcgtgcct tagaaattgc
    34981 ccattttggt caggatttgg aaaatcaaga gatcttgtat gaaccgctga ttatctgctt
    35041 ggatgatgaa cgtagtcaac tttatgagcg tatcaaccac cgagtggatt tgatgtttga
    35101 ggctgggctt ttggatgagg ccaagtggct gtttgaccat tcccctaatg tacaggctgc
    35161 taaaggaatt ggctataagg aactctttcc ttatttccgt ggagagcaga cctttgagga
    35221 agctcgtgag agtcttaaac aggcgacccg tcgttttgcc aagcgtcagc tgacctggtt
    35281 ccgtaatcgc atgcaggtca ccttttatca gattggagaa tctggtgtac aagaccgcat
    35341 tttaagccag atagaggagt ttttagatga ttgaaacgga gaaaaaagag gagcgagtcc
    35401 tgctgattgg tgtggaattg cagggtatgg acagttttga cctctccatg gaagaattgg
    35461 ctagtttagc gaaaacggca ggggcagtcg ttgtagatag ctacagacaa aaacgtgaaa
    35521 aatatgattc caagaccttc gtcggctctg gtaagttgga agagattgcg cttatggtgg
    35581 atgcagaaga aatcactact gtcatcgtca acaatcgtct gaccccaagg cagaatgtca
    35641 atctagagga agttctcggt gttaaggtca ttgaccgtat gcagttgatt ttggatatct
    35701 ttgccatgcg ggctcgaagc catgaaggga agctccaagt ccacctagcc caactcaaat
    35761 acctcttgcc tcgcttggtt ggtcagggga ttatgctcag ccgtcaggca gggggaattg
    35821 gttcccgtgg tcctggtgaa agccaactgg agctgaaccg tcgtagcgtt cgcaatcaaa
    35881 tcacggatat cgagcgccag cttaaggtgg ttgagaaaaa tcgtgcgact gtcagagaaa
    35941 aacgtttgga gtctagcact tttaagattg gtttgattgg ttatactaat gctgggaaat
    36001 caactatcat gaacatcttg accagtaaga cccagtatga agcagatgag ctctttgcga
    36061 ctctggatgc gacaaccaag agtattcatc tgggaggcaa tctccaagta actttgacag
    36121 ataccgttgg ctttatccaa gatttgccga cagagttggt gtccagtttc aagtcaacct
    36181 tggaagaaag caagcatgtg gaccttctgg ttcatgttat cgatgctagc aatccttacc
    36241 acgaggagca tgaaaaaacg gttctctcca tcatgaaaga cctggacatg gaagatattc
    36301 ctcacttgac gctttataat aaagcggatt tggtggagga tttcacgcct acccaaacgc
    36361 catataccct catttctgcc aagtctgagg acagtcgtga aaacttgcaa gcattattgc
    36421 tagataagat taaggaaatt tttgaagcat ttaccctgcg agtgcctttt tcaaagtcct
    36481 acaagattca tgatttagag agtgttgcaa ttctggaaga acgtgattat caggaagacg
    36541 gcgaagtgat tacaggctac atttccgaga aaaataaatg gaggttagaa gaattttatg
    36601 actgatatta aaactttggc tctaaagtat ggaggttata caagtctgga caaggtctat
    36661 ctggatcagc ttctagctgg taaaacagat caggagcagt taacacttat tacacctccg
    36721 ccaagtgttg ttaatgccta ctttgcagaa ctctatcaga aaaagagtcc tcaggctgcg
    36781 acggattatt ttgcagaact cagtcaggaa ctgaatcttt acaatactga gccaagtttc
    36841 accctagaaa ataagccttt tattcggctt aatctgtctg gtaaatcctt tggtttttgt
    36901 tatgagagtg acggccttgg tcggattttc tttgaaaatg aggagaaaat ctcggatgac
    36961 ttgctctttg aaattgcgca aattttcccc catcaattag tctttgaaga gtctggtaag
    37021 atttacatga agcctgtcga ggacgaggaa gttatcagcc tagaaagtct cacagctttg
    37081 actgatttgg aaagattggc tgatggtcga aaacgtctca aaggctacag ccaagaggat
    37141 ttattgcaag aagctgctgc tttttctggc aaacgctatt tccgatcgga aaaccgcaca
    37201 gccatgttat atattgatta attagaaagt atcgaatgga tattcaattt ttaggaacgg
    37261 gggctggtca gccctctaaa gcccgcaacg tttcaagtct cgccctgaaa cttttggatg
    37321 agattaacga agtttggctc tttgactgtg gagaaggtac gcaaaatcgc attctggaaa
    37381 ccacaattcg accacgtaag gtcagcaaaa tctttattac ccatctgcat ggagaccaca
    37441 tttttggttt gccaggtttc ctttctagcc gtgcctttca ggccaatgaa gagcagacag
    37501 atttggaaat ctacggacct caaggaatca agtcatttgt cttaaccagc cttcgtgtgt
    37561 caggttctcg tctgccctac cgcattcatt tccatgagtt tgaccaagat tctctgggta
    37621 aaattcttga aaccgataaa ttcactgtgt atgcagagga gctggaccac actattttct
    37681 gtgttggcta tcgtgtcatg caaaaggatc tagaagggac gctggatgct gaaaaactca
    37741 aggctgctgg tgttccgttc ggcccgcttt ttggtaaaat caaaaacggc caggatcttg
    37801 ttttggaaga cggaactgaa atcaaggcag cagactatat ctcagcgcca cgtccaggta
    37861 agattatcac tattttagga gacactcgaa aaacgggtgc cagtgtgcgt ctggctgtca
    37921 atgcagatgt cctagttcat gagtccactt atggcaaggg tgatgaaaaa attgctcgta
    37981 accatggtca ctcaactaat atgcaagctg cacaagtagc ggtagaagca ggtgccaaac
    38041 gcctcctact caaccatatc agtgcccgtt tcctctcaaa agatattagc aaactcaaga
    38101 aagacgctgc cacaattttt gaaaatgtcc atgtggtcaa agacttggaa gaagtggaaa
    38161 tctagcagtc acagaaagga taagtatgcc tactattctc attaccggag ctagcggtgg
    38221 tctagctcaa gaaatggtca aactcctgcc caatgaccaa ctcatcttgc ttggtagaaa
    38281 taaggaaaaa ttagcccaac tctacggaaa ttattcccat gcagaattga ttgaaattga
    38341 tattaccgac gattcagccc tagaagctct ggtaactgat ctttatctcc gctatggcaa
    38401 gattgatgtc ttgattaaca acgctggtta cgggattttt gagggatttg accagattgc
    38461 tgataaagat attcaccaga tgtttgaggt caataccttt gccctgatga atctgtctcg
    38521 tcaccttgcg gctcgtatga aggaaagcag caaagggcat atcatcaaca tcgtcagcat
    38581 ggcaggtcta atagctactg gcaagtctag tctttactca gcgaccaagt ttgcggctat
    38641 tggtttttca aatgctctgc gactcgaact tatgccctat ggagtctatg tgacaacagt
    38701 caatccaggt ccaatccgaa caggattttt cgaccaagcc gacccagatg gaacttatct
    38761 taaatcggtt gaccgcttcc tgctagaacc agatgcagtg gctaaaaaga ttgtcaagat
    38821 tataggaaaa aacaaacgag aactcaatct cccgattttg ttgaacctag ctcataagtt
    38881 ttataccctc tttcctaagc tagctgataa gttggcaggg gaaactttta attataagta
    38941 aaaagaacca atgtgcaggt tgttgctagc ctacatattg gttcttatca tttctcaact
    39001 atcaaactga acttcttcta ggagatagtc tataaagcgt tcgcccatct tagataggct
    39061 ggttttctca tgctggatat agaccagctc gatcgggtca tcaatatcca gtgggataga
    39121 aacgatattg tctccgttta ggttgctgtt caaaatccct gtcgcaatgg tataaccatc
    39181 caaaccaatc aagagattaa agagggtggc acggtcactg accacaatgg atttcttgtg
    39241 gtgttcttga gaaagaatct cttctgaaaa gtagaaggag ttgtgcgtcc cttggtcata
    39301 gctgaggtaa gggaaattct ccaaatcaga cagtttcacc ttgtctttct ttgccagagg
    39361 gttggtcttg ctgacaaaga tatgtggttg cgctgtgaag agatggtggg ctagcaggtg
    39421 attgtcatcc agcatcttgg ttaaaacatc acggttgtaa ctgtttaaga agaggacccc
    39481 gacctcactg cggaagttct tgacgtcgtc gataatctcc caagtccgag tttcacgaag
    39541 gaagagttcg tatttctcca tatcgctttt cttgagcaaa gagacaaagg cattgaccac
    39601 aaaggcatag tgttgagacg aaacgctaaa tagttcgcgg tgggcgacag gatttttata
    39661 gcgttcctcc agaagctggg tctgctcgac aacctgacgg gcataagaga gaaactccat
    39721 cccatcacgg gtcaaggtga ttcccttggg attgcggata aagatctcaa tgcccatttc
    39781 attttccaaa tctcgcactg cattggagag acttggctga gtgataaaga gttgcttggc
    39841 tgcctcattc atggagccag tttcgacgat tttgataata taatgtaatt gttgaattct
    39901 catgttttta ttgtaccata cttgccttag aatcgctaaa gaagatagga aaataaggag
    39961 cattgtgtga gtctcttctt gaaaaaaaca caaaattttg ctagaatgag tcttatgaaa
    40021 acattctatg atgtgcagca attcctcaaa cgatttggta ttattgttta catgggaaaa
    40081 cgcttatatg atattgaact gatgaagttg gaactatctc ggatttacga tgcagggttg
    40141 atggataaat tagactatct agaggcagaa gcagttcttc gcagagagca caaggtagaa
    40201 ttggattata ttgagaaaaa tggagaaaag aactaatggt tacttggatt ttgtgggcac
    40261 ttatactagc aatgttggcg tggatgggct ttaactatct tcgtattcgc cgtgcggcta
    40321 aaattgtgga caatgaggag tttgaagcct tgattcgtac gggtcaattg attgatttgc
    40381 gcgacccagc agaattccac agaaaacata tccttggtgc acgcaatatt ccttcaagtc
    40441 agttgaaaac tagtcttgca gcccttcgta aagataaacc tgtccttctc tacgagaacc
    40501 aacgtgcgca acgagttaca aatgcagctc tttacttgaa aaaacaaggt ttttctgaga
    40561 tttatatcct ttcttatggc ttggattctt ggaaagggaa agtgaagact agctaacctt
    40621 atttccaaat tagtcgaatg ataggatgaa gctattgttt tatagtataa ttaatttgta
    40681 taaaatttaa ggagttctta gaacataaaa gaaaagaaga aaaatccact ttttgtgggt
    40741 atcttgtcga ttattcttgg tttgttattt ccaattgtag gcctgatttt gggtatcata
    40801 ggattggtct tggctatttc ataccaaaaa gagtcataat tagacta
//
LOCUS       DAVKBK010000014        40235 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVKBK010000014 DAVKBK010000000
VERSION     DAVKBK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40235
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.014"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            5..75
                     /locus_tag="VWX69_000780"
     tRNA            5..75
                     /locus_tag="VWX69_000780"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VWX69_000781"
     tRNA            110..183
                     /locus_tag="VWX69_000781"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VWX69_000782"
     tRNA            266..355
                     /locus_tag="VWX69_000782"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VWX69_000783"
     tRNA            366..439
                     /locus_tag="VWX69_000783"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VWX69_000784"
     tRNA            443..515
                     /locus_tag="VWX69_000784"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VWX69_000785"
     tRNA            528..608
                     /locus_tag="VWX69_000785"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VWX69_000786"
     tRNA            613..683
                     /locus_tag="VWX69_000786"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VWX69_000787"
     tRNA            698..770
                     /locus_tag="VWX69_000787"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            784..855
                     /locus_tag="VWX69_000788"
     tRNA            784..855
                     /locus_tag="VWX69_000788"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:816..818,aa:Gln,seq:ttg)
     gene            865..948
                     /locus_tag="VWX69_000789"
     tRNA            865..948
                     /locus_tag="VWX69_000789"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:899..901,aa:Leu,seq:caa)
     gene            1055..2332
                     /locus_tag="VWX69_000790"
     CDS             1055..2332
                     /locus_tag="VWX69_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU9192162.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2408..3892
                     /locus_tag="VWX69_000791"
     CDS             2408..3892
                     /locus_tag="VWX69_000791"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU9192163.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3953..5233
                     /locus_tag="VWX69_000792"
     CDS             3953..5233
                     /locus_tag="VWX69_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9192164.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5237..5857
                     /locus_tag="VWX69_000793"
     CDS             5237..5857
                     /locus_tag="VWX69_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9192165.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6023..7135
                     /locus_tag="VWX69_000794"
     CDS             6023..7135
                     /locus_tag="VWX69_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9192166.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7458..7883
                     /locus_tag="VWX69_000795"
     CDS             7458..7883
                     /locus_tag="VWX69_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU9192167.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7894..8253
                     /locus_tag="VWX69_000796"
     CDS             7894..8253
                     /locus_tag="VWX69_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU9192168.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8360..9004
                     /gene="pcp"
                     /locus_tag="VWX69_000797"
     CDS             8360..9004
                     /gene="pcp"
                     /locus_tag="VWX69_000797"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU9192169.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(9032..9889)
                     /locus_tag="VWX69_000798"
     CDS             complement(9032..9889)
                     /locus_tag="VWX69_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU9192170.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10019..11161
                     /gene="tgt"
                     /locus_tag="VWX69_000799"
     CDS             10019..11161
                     /gene="tgt"
                     /locus_tag="VWX69_000799"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU9192171.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11259..13076
                     /locus_tag="VWX69_000800"
     CDS             11259..13076
                     /locus_tag="VWX69_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU9192172.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13229..14380
                     /gene="nagA"
                     /locus_tag="VWX69_000801"
     CDS             13229..14380
                     /gene="nagA"
                     /locus_tag="VWX69_000801"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU9192173.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14543..15601
                     /locus_tag="VWX69_000802"
     CDS             14543..15601
                     /locus_tag="VWX69_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU9192174.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15752..16117
                     /locus_tag="VWX69_000803"
     CDS             15752..16117
                     /locus_tag="VWX69_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU9192175.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16193..17134
                     /locus_tag="VWX69_000804"
     CDS             16193..17134
                     /locus_tag="VWX69_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU9192176.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17082..18098
                     /locus_tag="VWX69_000805"
     CDS             17082..18098
                     /locus_tag="VWX69_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU9192177.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18100..18426
                     /locus_tag="VWX69_000806"
     CDS             18100..18426
                     /locus_tag="VWX69_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEU9192178.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18419..18823
                     /locus_tag="VWX69_000807"
     CDS             18419..18823
                     /locus_tag="VWX69_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU9192179.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18828..19088
                     /locus_tag="VWX69_000808"
     CDS             18828..19088
                     /locus_tag="VWX69_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192180.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19051..19512
                     /locus_tag="VWX69_000809"
     CDS             19051..19512
                     /locus_tag="VWX69_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9192181.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19490..19936
                     /locus_tag="VWX69_000810"
     CDS             19490..19936
                     /locus_tag="VWX69_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9192182.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            20039..20626
                     /locus_tag="VWX69_000811"
     CDS             20039..20626
                     /locus_tag="VWX69_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9192183.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKVILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20687..21640
                     /locus_tag="VWX69_000812"
     CDS             20687..21640
                     /locus_tag="VWX69_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9192184.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21691..22881
                     /locus_tag="VWX69_000813"
     CDS             21691..22881
                     /locus_tag="VWX69_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU9192185.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYFAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23030..23401
                     /gene="rnpA"
                     /locus_tag="VWX69_000814"
     CDS             23030..23401
                     /gene="rnpA"
                     /locus_tag="VWX69_000814"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU9192186.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23376..24200
                     /locus_tag="VWX69_000815"
     CDS             23376..24200
                     /locus_tag="VWX69_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9192187.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24219..25205
                     /locus_tag="VWX69_000816"
     CDS             24219..25205
                     /locus_tag="VWX69_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU9192188.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25256..25879
                     /locus_tag="VWX69_000817"
     CDS             25256..25879
                     /locus_tag="VWX69_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU9192189.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26010..27467
                     /locus_tag="VWX69_000818"
     CDS             26010..27467
                     /locus_tag="VWX69_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9192190.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27490..27771
                     /locus_tag="VWX69_000819"
     CDS             27490..27771
                     /locus_tag="VWX69_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9192191.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27848..28333
                     /locus_tag="VWX69_000820"
     CDS             27848..28333
                     /locus_tag="VWX69_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9192192.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGLYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28350..29015
                     /locus_tag="VWX69_000821"
     CDS             28350..29015
                     /locus_tag="VWX69_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU9192193.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29019..29882
                     /locus_tag="VWX69_000822"
     CDS             29019..29882
                     /locus_tag="VWX69_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU9192194.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29884..30588
                     /locus_tag="VWX69_000823"
     CDS             29884..30588
                     /locus_tag="VWX69_000823"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU9192195.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30767..32440
                     /locus_tag="VWX69_000824"
     CDS             30767..32440
                     /locus_tag="VWX69_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9192196.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            32552..33643
                     /gene="ulaG"
                     /locus_tag="VWX69_000825"
     CDS             32552..33643
                     /gene="ulaG"
                     /locus_tag="VWX69_000825"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU9192197.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33757..35733
                     /gene="tkt"
                     /locus_tag="VWX69_000826"
     CDS             33757..35733
                     /gene="tkt"
                     /locus_tag="VWX69_000826"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9192198.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35850..36149
                     /gene="yajC"
                     /locus_tag="VWX69_000827"
     CDS             35850..36149
                     /gene="yajC"
                     /locus_tag="VWX69_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9192199.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36196..36624
                     /locus_tag="VWX69_000828"
     CDS             36196..36624
                     /locus_tag="VWX69_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU9192200.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLCQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36626..37036
                     /locus_tag="VWX69_000829"
     CDS             36626..37036
                     /locus_tag="VWX69_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192201.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37336..39987
                     /gene="adhE"
                     /locus_tag="VWX69_000830"
                     /gene_synonym="adhC"
     CDS             37336..39987
                     /gene="adhE"
                     /locus_tag="VWX69_000830"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU9192202.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12207 a         7212 c         9064 g        11752 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttaacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tattggggta tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga
      841 atccagctac cccagttact atttgccggc gtggcggaat tggcagacgc gctggactca
      901 aaatccagtg tccgcaagga cgtgccggtt cgaccccggc cgccggtata gtatagtgtt
      961 aggaacgttg ttattcttcg ttcctttttt atattatttt tggtataatt atagttattc
     1021 aaattttatt tagattaaga aagtgtaggg gagtatgtct tgttctatcg atttattaaa
     1081 acatcggtat ttgaaaaata ttaaagaaaa tcctgaattg tttgtcggaa ttgagttgga
     1141 gtatcctgtt gcaagtttag aaggggatgc tacagatgtt gaagttatga aggatctatt
     1201 tcattattta gtttctactt tggatctcac cgtagcaaag gtagatgatt ttggcaatct
     1261 gatccagtta gtagatccga taagtcagga tgctatttta tttgaagttt cctatacaac
     1321 gattgagttt gcatttggta aggctgaaac gattcaagag gtcgaaaatc gtttcaataa
     1381 ttatatgaat gtaattcaga gaaagttagc tgaatcaaat catgctattg ttggctgtgg
     1441 tatccatccc aactgggata aaaatgagaa ttgtccagtg gcttatccac gctatcagat
     1501 gttgatggat tatttgaatt tgagtagaaa tattattaaa tcagatttac atcatttccc
     1561 tgaatatggt acttttatct gtgggagcca ggttcagctg gatatttcaa aaaccaacta
     1621 cttacgggtg attaatgctt ttactcaaat tgaagcggct aaggcttatt tatttgcaaa
     1681 ctctgaattt tcgggtgcgg attgggatac gaaaatttca agggatattt tctgggaaga
     1741 atctatgcat ggtatctatc cagagaatgt tggggtcaat gctagactcc ttaatgatga
     1801 agctgatttt tttgactatc taaatcattc tgcgattttt actgcggaac gtgatgggca
     1861 gacctattat ttttatccta ttcaggctgg ggactatttg gctacgtccg aaatccaagc
     1921 atttgctctg aatggggatg aggttattat ttacccccaa gagaaggatt ttgaaactca
     1981 tcgtagttac cagtaccaag atttaacgac tcgaggaaca gttgagtttc gtagtgtgtg
     2041 tacacagcca cttgatagga cttttgcttc tgcagctttt cacttgggat tattggttaa
     2101 tttagacaag ttagaagctt acttagaaac agcacctttc tttaaagtat ttggttatga
     2161 ttacaagtct ttaaggagac aattttctaa gaaaaatctt acagatgagg aagaaactac
     2221 gattattgaa ttttccaaag acttactcct actagctgag gagggactag tggtgagaaa
     2281 taaggaagaa atgacctatt tacagccttt gagagaagaa ttgagcctat aatttctctt
     2341 ataaagggag aattttctga aaaatcatga tataatggac gagactatag ataaaggata
     2401 gagagtaatg acattagttt atcaatcaac gcgtgatgcc aacaatacag taactgccag
     2461 ccaagcaatt ttgcaaggtt tggcgacgga cggcggtttg tttacaccgg atacttatcc
     2521 aaaggtagat ttgaactttg acaaattgaa agatgcttct taccaggaag ttgctaagct
     2581 agttttgtca gcatttttag atgactttac agttgaggag ttggactact gtatcaacaa
     2641 tgcctacgat agcaaatttg atactccagc tattgcacca ttagtgaaat tagatgggca
     2701 atacaatttg gaacttttcc atggttcaac gattgccttt aaggatatgg ccttgtctat
     2761 tttgccatac tttatgacga ctgctgctaa gaaacatggt ttggagaaca agattgttat
     2821 cttgacagcg acatctggtg acacggggaa agctgctatg gcggggtttg cgaatgtgcc
     2881 tggtactgag attatcgtct tttatccaaa ggatggtgtc agcaagattc aagagttaca
     2941 aatgaccact cagactggcg acaatactca tgttattgct attgatggta actttgacga
     3001 tgcgcaaaca aatgtgaagc acatgtttaa cgacgtggct cttcgtgaaa aattgactac
     3061 caacaagttg caattttcat cagctaactc tatgaacatt ggtcgtctgg tgccacaaat
     3121 tgtttattat gtttatgctt acgctcaatt ggttaagact ggtgaaattg tagctggtga
     3181 aaaggttaac ttcacagtac caacaggaaa ctttggaaat atcttggctg ccttttatgc
     3241 caaacaaatt ggtttgccag ttggtaaatt aatctgtgct tcaaatgaca acaatgtttt
     3301 gacagacttc tttaaaacac gtgtctatga caaaaaacgt gagtttaagg taacaaccag
     3361 cccatctatg gatatcttgg tatcttcaaa cttggagcgc ttgattttcc atcttttggg
     3421 aaataatgct gaaaagacaa ctgaacttat gaatgccttg aacacgcaag gacaatataa
     3481 gttgacagac tttgatgcag agattttgga cctctttgca gctgaatatg cgactgagga
     3541 agaaacggca gcagagatca agcgtgtttg tgagttagat tcttatatcg aggaccctca
     3601 tacagctgtt gcttcagcag tttataaaaa ataccaatcg gccactggag atgtaactaa
     3661 gacagtgatt gcttcaacag ctagtccata caagttccca gtagttgcag tagaagctgt
     3721 aactggaaaa gcaggtttaa cagactttga agccttggct caattacatg aaatctcagg
     3781 cgttgcagtg ccaccagcag ttgatgggct tgaaatagct ccaattcgtc acaagacaac
     3841 agtggcagct gctgacatgc aagcagcggt tgaggcttat ttaggacttt aagacagagg
     3901 gagcaaactc ggttgggaaa ccaactgagt ttcttttcat caggaggaga gattgtttaa
     3961 gaaaaataaa gacattctta atattgcatt gccagctatg ggtgaaaact ttttgcagat
     4021 gctaatggga atggtggaca gttatttggt tgctcattta ggattgatag ctatttcagg
     4081 ggtttcagta gctggtaata ttatcaccat ttatcaggcg attttcatcg ctctgggagc
     4141 tgctatttcc agtgttattt caaaaagcat agggcagaaa gaccagtcga agttggccta
     4201 tcatgtgact gaggcgttga agattacctt actattaagt ttccttttag gatttttgtc
     4261 catcttcgct gggaaagaga tgataggact tttggggacg gagagggatg tagctgagag
     4321 tggtggactg tatctatctt tggtaggcgg atcgattgtt ctcttaggtt taatgactag
     4381 tctaggagcc ttgattcgtg caacgcataa tccacgtctg cctctctatg ttagtttttt
     4441 atccaatgcc ttgaatattc ttttttcaag tctagctatt tttgttctgg atatggggat
     4501 agctggtgtt gcttggggga caattgtgtc tcgtttggtt ggtcttgtga ttttgtggtc
     4561 acaattaaaa ctgccttatg ggaagccaac ttttggttta gataaggaac tgttgacctt
     4621 ggctttacca gcagctggag agcgacttat gatgagggct ggagatgtag tgatcattgc
     4681 cttggtcgtt tcttttggga cggaggcagt tgctgggaat gcaatcggag aagtcttgac
     4741 ccagtttaac tatatgcctg cctttggcgt cgctacggca acggtcatgc tgttggcccg
     4801 agcagttgga gaggatgatt ggaaaagagt tgctagtttg agtaaacaaa ccttttggct
     4861 ttctctgttc ctcatgttgc ccctgtcctt tagtatatat gtcttgggtg taccattaac
     4921 tcatctctat acgactgatt ctctagcggt ggaggctagt gttctagtga cactgttttc
     4981 actacttggg acccctatga cgacaggaac agtcatctat acggcagtct ggcagggatt
     5041 aggaaatgca cgcctccctt tttatgcgac aagtatagga atgtggtgta tccgcattgg
     5101 gacaggatat ctgatgggga ttgtgcttgg ttggggcttg cctggtattt gggcagggtc
     5161 tctcttggat aatggttttc gctggttatt tctacgctat cgttaccagc gctatatgag
     5221 cttgaaagga taggaaatgc aaaaaacagc ttttatttgg gatttagacg ggactttatt
     5281 ggactcttac gaagcgattt tatcagggat tgaggagact tttgctcagt tttctattcc
     5341 ttatgataag gagaaggtga gagagtttat cttcaagtat tcggtgcaag atttgcttgt
     5401 gcgggtggca gaagatagaa atctggatgt tgaggtgcta aatcaggtgc gtgcccagag
     5461 tctggctgag aagaatgctc aggtagtttt gatgccaggt gcgcgtgagg tgctagcttg
     5521 ggcagacgaa tcaggaattc agcagtttat atatactcat aaggggaaca acgcttttac
     5581 cattctcaag gacttggggg tggaatccta ttttacagag attttaacca gtcagagtgg
     5641 ctttgtgcgg aagccaagtc cagaagcggc tacctatctg ctagataagt atcagttgaa
     5701 ttctgataat acttattata taggggatcg gactctggat gtggaatttg cccagaatag
     5761 tgggattcaa agcatcaact ttttagagtc tacttatgaa gggaatcaca ggattcaagc
     5821 gttagcagat atttcccgta tttttgagac taagtgataa aaagattgtg tcagttttgt
     5881 gacagagacc taacaaacta tttcaagtaa cctagtttgt tacaaggaat agacagttct
     5941 gttaaatagg cccgagaggg ctttttttct acattttttg tgttatgata gacaggtact
     6001 catttgaaag gaatttgaaa gaatgaagaa aagaatgtta ttagcgtcaa cagtagcctt
     6061 gtcatttgcc ccagtattgg caactcaagc agaagaagtt ctttggactg cacgtagtgt
     6121 tgagcaaatc caaaacgatt tgactaaaac ggacaacaaa acaagttata ccgtacagta
     6181 tggtgatact ttgagcacca ttgcagaagc cttgggtgta gatgtaacag tgcttgcgaa
     6241 tctgaacaaa atcactaata tggacttgat tttcccagaa actgttttga caacgactgt
     6301 caatgaagca gaagaagtaa cagaagttga aatccaaaca cctcaagcag actctagtga
     6361 agaagtgaca actgcgacag cagatttgac cactaatcaa gtgaccgttg atgatcaaac
     6421 tgttcaggtt gcagaccttt ctcaaccaat tgcagaagtt acaaagacag tgattgcttc
     6481 tgaagaagtg gcaccatcta cgggcacttc tgtcccagag gagcaaacga ccgaaacaac
     6541 tcgcccagtt gaagaagcaa ctcctcagga aacgactcca gctgagaagc aggaaacaca
     6601 agcaagccct caagctgcat cagcagtgga agtaactaca acaagttcag aagcaaaaga
     6661 agtagcatca tcaaatggag ctacagcagc agtttctact tatcaaccag aagagacgaa
     6721 aataatttca acaacttacg aggctccagc tgcgcccgat tatgctggac ttgcagtagc
     6781 aaaatctgaa aatgcaggtc ttcaaccaca aacagctgcc tttaaagaag aaattgctaa
     6841 cttgtttggc attacatcct ttagtggtta tcgtccagga gacagtggag atcacggaaa
     6901 aggtttggct atcgacttta tggtaccaga acgttcagaa ttaggggata agattgcgga
     6961 atatgctatt caaaatatgg ccagccgtgg cattagttac atcatctgga aacaacgttt
     7021 ctatgctcca ttcgatagca aatatgggcc agctaacact tggaacccaa tgccagaccg
     7081 tggtagtgtg acagaaaatc actatgatca cgttcacgtt tcaatgaatg gataaacccg
     7141 acttgataac atcattttga cgaatgagat ctagctttcg tgatggaaag cgattctcgt
     7201 tcgttttttc tttgtcatac tcttcgaaaa tctcttcaaa ccacgtcagt tttatctgaa
     7261 acttcaaagc tgtgctttga gcaacctgcg actagcttcc tagtttgctt tttgattttc
     7321 attgagtatc aatttgaatg gaaaatggaa agttatcatc ttgtaatgag ttaagcaaca
     7381 ttcttgcaat ctattttact ttatatcaca attaattagt caaatattga taaatcaata
     7441 aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc cgcttgtctg
     7501 agcaagcgag tacgcaattg tttgaaaaaa ggcttgggat tagtttgaca cggtatcaga
     7561 ttttactgtt tttgctggag cattctcctt gtaaccaaat ggcggttcag gagcgtttga
     7621 aaattgatca ggctgctttg acacggcatt tcaaaatttt ggaaacggaa ggtttggtgg
     7681 agcgtcatcg taatcctgaa aatcagcggg aagtgttggt agaggctgcg aagtatgcca
     7741 aggagcagtt agtggtgaat ccccctctgc aacatatcag ggttaaggaa gagatagaaa
     7801 gtatcttaac agagtttgag agaacagaac tcagccgttt attaaataaa ttggttttgg
     7861 gtattgaaaa tatagaaatt taaggagaaa tagatgtcaa ttattttaac aacgatcgtt
     7921 gctttggagc atttttacat tttttatttg gaaagtattg ccacgcaatc agatgcgact
     7981 agtcgtgtat ttaatatgga aaaggaagaa ttggctcatc cgtcagtaag ttcattgttc
     8041 aaaaatcaag gaatttataa ggctctgcta ggagtctttc tcttgtatgt catttatttc
     8101 tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc tgcgacttac
     8161 ggctctttaa cagcggataa aaaaattatt ttgaaacaag gtggatcagc tattttggcc
     8221 ttgattagta ttttactctt taaatacact tgaaggtcga ttctaatctc gctaatcctt
     8281 tttaatccag aataagggaa atatgttata cttgttttta agaaaaaagt ctcattgaat
     8341 tggttttgag gagttagaaa tgaaagtatt agtgacaggt tttgagccct ttggagggga
     8401 aaagggcaat ccagctttgg aggccattaa aggtttacca gctgaaatcc atggtgctga
     8461 ggtccgttgg ctagaggtgc cgacagtttt tcacaaatct gctcaagtat tggaagaaga
     8521 gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg gaagaactag
     8581 tttgacacct gaacgagtga ccattaatca agacgatgca tgcatttctg ataacgaaga
     8641 taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact ttagtagttt
     8701 gccgattaaa gcgatggttc aagctataaa aaaagagggc ttaccggcct ctgtttccaa
     8761 tacggcaggg acttttgtct gcagccattt gatgtatcag gctctctatt tggtagaaaa
     8821 gaaatctcca tatgttaagg caggttttat gcatattcct tatatgatgg aacaggtggt
     8881 gaacagaccg actactccag ctatgagttt agtggatatt cggcgaggga tagaagcagc
     8941 aatcggcgct ataatagaac atggagatca ggaactcaag ttggtaggcg gagaaactca
     9001 ttgatagaaa aaagcttgag gagaaaaacc ttcaagcttt tggacgtttt cgggccaata
     9061 ctgctcggta aaacataatt ttagtgcatt ggatataagg taggagtgaa aaactagcaa
     9121 tgccaaaggt aatccaattg aggaagtacc aaggaagaag ctgtaaatct aggacaaagt
     9181 gctggaactt gtagcccttc ataaaggaac ggctagtttt taggattcgt cttggtggga
     9241 cctgtcctag gtctagacta taacagagaa gaaattccac ctgtgaatag gcataatact
     9301 gtggaatata gaggatattt cctacaatga tcaagatgag acttgcaaga aagtagagtc
     9361 caaagaccat gaggaaacgc tcggtttcaa ctgatgagag atctagattt ggaaactcag
     9421 gatgtagggt gacgaatttt ttggctaaaa agctactata aaagaggagg taaatcccaa
     9481 gtaaattagg gatactccat aaaaagagat agaaacgttt gagaagtagg gtcaaaaagg
     9541 tttgagaaaa gcgctcctca tcaaagagag ctaggctgtt ttttacagat ggctccgttt
     9601 tagaatcttt catgagtgtc agtgttgcat agacggaact ggtcaaaaga atagtcccga
     9661 taaaggagac tagtagagga aagaggtagg tttgaagtat ttggccaagt atgctgaaaa
     9721 atggctgttc taaaacagtc ccgtggatcc gagataaggg attaagaaaa ccagataaga
     9781 tgaccagcat actgggaagg atatagagga gaaagagacg gggggtgtca gcctgaaaat
     9841 gttttgactc ctgacgaatt gtttttaaat caatttttgg atagttcatt ctcttattat
     9901 accatagttc ttatacatag ttcgtgacag ttcctacttt ttttgataaa atcatacagt
     9961 gtgtccttgg gcacactgta tgaactggga ctgtctttcc cagcttcgga ggtaaaaaat
    10021 gtcagattca ccaatcaaat atcgtttgat taagaaagaa aaacacacag gagctcgtct
    10081 gggagaaatc atcactcccc acggtacctt tccgacacct atgtttatgc cagttgggac
    10141 acaagccact gtcaaaactc agtcacctga agaattgaag gagatgggtt cgggaattat
    10201 cctatcaaac acctatcatc tctggcttcg ccctggagat gaactcattg cacgcgctgg
    10261 tggtctccac aagttcatga attgggacca gcctatcttg acagatagtg gtggttttca
    10321 ggtttattct ttagcagata gccgtaatat cacagaagaa ggagtaacct ttaaaaatca
    10381 tctaaatggt tctaagatgt tcctatcccc agaaaaagcc atctctattc agaataatct
    10441 gggttcagac atcatgatgt cctttgatga atgtcctcag ttttatcaac cttatgacta
    10501 cgttaagaaa tcgatcgagc gtaccagccg ttgggctgag cgtggtttga aggctcaccg
    10561 tcgtccacat gaccaaggtt tgtttggaat tgtgcaaggt gcaggatttg aagaccttcg
    10621 ccgccaatca gctcatgatc ttgtcagcat ggatttctca ggctactcta tcggtggttt
    10681 ggcagtggga gaaacccatg aagagatgaa tgcggtcttg gactttacaa ctcaactgct
    10741 acctgaaaat aaacctcgtt atctgatggg tgtgggagcg ccagatagct tgatcgatgg
    10801 ggtcattcgt ggggtggata tgtttgactg tgtcttaccg actcgaattg ctcgtaacgg
    10861 gacttgtatg accagtcaag gacgtttggt tgtgaaaaat gcccagtttg ctgaggactt
    10921 tacgccactg gatcctgagt gtgactgcta cacatgtaat aactatacac gcgcttacct
    10981 tcgtcacctg ctcaaggctg atgaaacctt tggtatccgc ttgactagct accacaatct
    11041 ttacttcttg cttaacctga tgaagcaagt gcgacaagcc atcatggatg acaatctctt
    11101 ggaattccgt gagtattttg tggaaaaata tggctataat aagtcaggac gtaatttcta
    11161 aaatggaatt gatataaaaa aatcctaagt tttctcttag gatttttctt ctttttttga
    11221 tagaataaag tgtacaatga aaggaagaat aaactcgtat gcgcattaaa tggttttcct
    11281 tgattaggat tataggttta cttttggtac tcttgtatca cttctttcag acgatctttc
    11341 ctggaggatt tttcggggta gatgtctttt tcacattttc aggtttcctg attacagctc
    11401 tactcattga agaattttct aagaacaatg agattgattt gataggattt tttagaagac
    11461 gcttttatcg gattgtgcca cctgtggttt tgatggtctt ggtgaccatg ccttttactt
    11521 tcttggttcg ccaagactat gttgctggaa ttggtggcca gattgcgggc gtcttaggct
    11581 ttatgaccaa cttctatgaa ctcctaacag gtgggagtta tgaatctcag ttcattcctc
    11641 atttgtttgt tcataattgg agtttggcag ttgaggttca ctactatatt ctttggggat
    11701 tggcagtttg gttcttatcc aaacaagcta aatcaaatgg tcagttgaag gggatggtct
    11761 ttctcttatc tgctgctgcc ttcttgatca gtttcttctc catgtttatt ggtagttttc
    11821 tagtgacctc ttattcctct gtttatttct ccagtttaac tcatgtctat ccattctttt
    11881 tgggaagtat gttagcaact attgtaggtg ttcgtcagac gacttccctc gtcaagcagt
    11941 tggataaaat ctgggattta cgaaagactt tggtagtttt tggaggaggc tttggtttcc
    12001 tagttctttt gactttcttt gtcaaattca cttatctttt tgcctatctt atcggcttct
    12061 tgcttgccag tcttgcagct cttgccatga ttctggcggc gcgtgtctta catgaaaaga
    12121 cacatcatat acaggagccg aagattatca gctttttagc ggatactagc tatgcggttt
    12181 atcttttcca ttggcctttc tatatcattt tctcacagtt gacatcaaat cttcttgctg
    12241 tattactgac tctgatttgt tcttatggct ttgccagtct gtcattctat gtattggaac
    12301 cttggattgc aggcaagaac acacctattt tacaaactct tcgtcccctg ccttatattc
    12361 acgcaattct tgtagcaggt acaggaatct tgaccatcat tgtctgcacg gtgaccttgt
    12421 tggcaccaca agtgggagcg tttgagacag acttgactgt caatggcttg aagcaagctg
    12481 caacaaatat tggccagacc aaggtgatgg cagaacgggc agatgcaaac agtttgggaa
    12541 ttgctgatgg cactatgtta attggtgact cagtggcttt aagggcaaat acagcactac
    12601 agacagctct tcctggagca cagattaacg cgcaggtcag cgtaacaacc aagaccgcaa
    12661 atgaaatcat gctaaataat agccagaata aatttttacc taagacggtg gtcattgcga
    12721 ctggggtaaa taatcctgag aattacaagg atgactggga cagtatcgtg aaaaatcttc
    12781 ctaagggaca ccatatgatt ttggtgactc cttatgaggg agataagaca aaagagacct
    12841 atgccatcgt tgagaaggct gctgcctata tgagagaatt ggcagagaag acaccttaca
    12901 ttacgatagc agattggaat caagttgcga aagagcatcc agaaatttgg gctggaacag
    12961 accaggttca tttcgggagt gagagtagca ctatcgaagc aggagcaaaa ttgtatgcag
    13021 atacgattgc cacagctttg cagacagctc aagacaagcc ggttaaatca aaataacttg
    13081 tattaaaaaa gagaagagtt ggagaaatcc agctctttta aaatatctcc aaaaaatagg
    13141 tctataccat ttacaaataa aaaagaaagg tttataatgt aattgacata ataaattgta
    13201 gaatcaatct tttaaggagg ttaacattat gcctaactat attaaagcgg atcagttttt
    13261 ctacccacac ggagttcgtc gaggtggtta cttggaactt gtggacggca agtttgggaa
    13321 acatgtagag cagattcctg aaggggctga ggtgattgac tatacaggtt atagcattgc
    13381 cccaggtctt gtggatactc atattcatgg atatgcaggt gtagatgtga tggacaacaa
    13441 cattgaaggt acattgcata ctatgagtga aggacttctt agtaccggtg ttaccagttt
    13501 cttacccaca actttaacag ccacttatga gcaattgctt gcagtcactg aaaatcttgg
    13561 aaaccattat aaagaagcaa caggtgctaa gattcgtggg atttattatg aaggtccata
    13621 tttcacagaa acttttaagg gggcacaaaa tccaacttat atgagagacc cgggtgttga
    13681 ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt aataaaattg cccttgcacc
    13741 agaacgtgat ggggtggaag actttgttcg tacagttacg ggcgaaggtg tgacggttgc
    13801 tcttggacat tcaaacgcga cttttgatga agccaaaaaa gcagtcgatg ctggagcgag
    13861 tgtttgggtg catgcctata atggaatgcg tgggttgact caccgtgaat tgggtatggt
    13921 tggagccatg taccaattgc cacataccta tgcagagttg atctgtgatg gtcaccacgt
    13981 agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga acagaaaaca tcgctcttat
    14041 cacagactgt atgacagctg ggggattgga agacggagat tatatgttgg gagaattccc
    14101 agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca ggtaacttgg caggttctat
    14161 cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg ggaattgcga atccgcatga
    14221 agcagtcatg atggccagct tcaacccagc taaatccgtt cacatcgatg acgtctgtgg
    14281 ccaaatccgt gaaggctacg acgctgactt catcgtatta gataaagatt tggaattggt
    14341 agcaacctat ctagatggcg taaaacgtta tcaagcataa gagagaaggc agaagttaga
    14401 gactagcttc tgctttttta tacagggtac tttactggta aataaaaagt taaaaaaatc
    14461 acaaaaaaag cttgaagaaa caaagaaaaa ggcttacaat tgaactataa atattacaaa
    14521 taaaaaaacg gaggagtgct ttatgaaagc ctatacttat gttaaaccag gacttgcttc
    14581 ttttgttgat gtagacaaac cagttattcg caagccaaca gacgctattg tgcgtattgt
    14641 aaaaaccact atttgtggaa cagacctcca tattatcaaa ggggatgttc ctacttgcca
    14701 aagtggtacc attcttggcc acgaagggat tgggattgtt gaagaagttg gggaaggagt
    14761 ttccaacttc aaaaaaggcg acaaggtctt gatttcttgc gtctgtgcct gtggtaaatg
    14821 ctactactgt aaaaaaggaa tttatgccca ctgtgaagac gaagggggct ggattttcgg
    14881 tcacttgatt gatggtatgc aggctgaata tctacgtgtc cctcatgcag ataatactct
    14941 ttaccatact ccagaagact tgtcagatga agctttggtt atgctgtcag acattctgcc
    15001 tactggatat gaaattggtg tcttaaaagg gaaagtagaa cctggttgca gcgtagccat
    15061 tattggttca ggtccagttg gattggctgc tcttttaaca gcccaattct attcaccagc
    15121 taaattgatt atggtagacc tagacgataa ccgcttggaa actgccctat cattcggtgc
    15181 gactcataag gttaattctt cagaccctga aaaagccatt aaagaaattt atgatttgac
    15241 agatggtcgt ggtgtggatg tcgctatcga agctgttggt attcctgcaa catttgattt
    15301 ctgtcaaaag attatcggtg tagacggaac ggttgccaac tgtggtgtgc atggtaaacc
    15361 agttgaattc gatttagata aactttggat tcgcaacatc aatgtaacaa ctggtttggt
    15421 atctacaaat acgactccac aattgttgaa agcacttgaa agtcataaga ttgaaccaga
    15481 aaaattggta actcactatt tcaaactcag tgaaattgaa aaagcctatg aagtcttcag
    15541 taaggcagca gaccaccatg ccattaaggt cattatcgaa aacgatatct cagaagccta
    15601 agtagtaaaa atatttttgt acataagtaa atagaaattc agtcatccat cagatggctg
    15661 gattttttat caaaaaatta agaaatgagc atatttcttt ccttgtctgg cggaattggt
    15721 tataatatac ggtacaaagg aatgaatgaa tatgtatcgt gttatagaaa tgtacggaga
    15781 ttttgaaccg tggtggttct tagaaggttg ggaagaagat attgtagcaa gtagaaaatt
    15841 tgaccagtat tatgatgctc tcaaatacta caaaacttgc tggtttagat tggaacaaga
    15901 atcccctctt tataaaagta gaagcgactt gatgaccatt ttttgggacc cggaagacca
    15961 acgctggtgt gatgaatgtg atgagtattt acaacaatac cattctttgg ctcttttgca
    16021 ggatgagcag gttatcccag acgaaaaact acgctcaggc tatgaaaaac aaaccagtca
    16081 ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga aaagtaactt ttttggagtt
    16141 gcttttttta tttttctaac gctttgcgaa tagtataggt gaggaggtaa gtatggttca
    16201 agaaattgca caagaaatca ttcgttcagc tcggaaaaaa gggacgcagg atatttattt
    16261 tgtccctaag ttagacgcct atgagcttca tatgagggta ggagacgagc gctgtaaaat
    16321 tggtagctat gattttgaaa agtttgcagc cgttatcagt cactttaagt ttgtggcggg
    16381 tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc tgtgattatg cctatgacca
    16441 gaagatggcg tctctacgtt tatctactgt aggcgattat cgggggcatg agagtttggt
    16501 tatccgtttg ttgcacgatg aggagcagga cttgcatttt tggtttcagg atattgaaga
    16561 attaggcaag cagtacaggc aacggggact ctatcttttt gctggtccgg ttgggagtgg
    16621 taagacgacc ttgatgcatg aattgtccaa gtcactcttt aaaggacagc aagttatgtc
    16681 catcgaagat cctgtcgaaa tcaagcagga cgacatgctt cagttgcagt tgaacgaagc
    16741 aatcggccta acctatgaaa atctaatcaa actttccttg cgtcatcgac cagatctctt
    16801 gattatcgga gaaattcgtg acagcgagac ggcgcgtgca gtggtcagag ctagtttgac
    16861 aggtgcgaca gtcttttcaa ccattcacgc caagagtatc cgaggtgttt atgagcgtct
    16921 gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt ctgcaaggag tctgctacca
    16981 gagattaatc gggggaggag gaatcgttga ctttgcaagc agagattatc aagaacacca
    17041 agcagccaag tggaatgagc aaattgacca gcttcttaaa gatggacata tcacaagtct
    17101 tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa aaatatcatc accctattta
    17161 acaatctctt ttctagcggt tttcatctgg tggagactat ctccttttta gataggagtg
    17221 ctttgttgga caagcagtgt gtgatccaga tgcgtgcggg cttgtctcag gggaaatcat
    17281 tctcagaaat gatggaaagt ttgggatgtt caagtaccat tgtcactcag ttatctctag
    17341 ctgaagttca tggcaatctt cacctgagtt tgggaaagat agaagaatat ctagacaatc
    17401 tggccaaggt caagaaaaag ttaattgaag tagcgaccta tcctttgatt ttgctgggtt
    17461 ttcttctctt aattatgctg gggctacgga attacctgct cccacaactg gatagtagca
    17521 atattgccac ccgaattatc ggtaatctgc cacaaatttt tctaggcatg gtagggcttg
    17581 tttccgtgct tgccctttta gcactaactt tttataaaag aagttctaag atgagtgtct
    17641 tttctatctt agcacgcctt ccctttattg gaatctttgt gcagacctac ttgacagcct
    17701 attatgcacg tgaatggggg aatatgattt cacagggaat ggagctgacg cagatttttc
    17761 aaatgatgca ggaacaaggt tcccagctct ttaaagaaat cggtcaagat ctggctcaaa
    17821 ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac ctatcctttc tttaggaagg
    17881 aattgagtct catcatagag tatggggaag ttaagtccaa gctgggtagt gagttggaaa
    17941 tctatgctga aaaaacttgg gaagcctttt ttacccgagt caaccgcacc atgaatttgg
    18001 tgcagccact ggtttttatc tttgtggcac tgattatcgt tttactttat gcggcaatgc
    18061 tcatgcccat gtatcaaaat atggaggtaa atttttaaaa tgaaaaaaat gatgacattc
    18121 ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga tgttagtagt cttgctgatt
    18181 atcagcgtgc ttttcttgct ctttgtacct aatctgacca agcaaaaaga agcagtcaat
    18241 gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc aggcagaact ttatagcttg
    18301 gataaaaatg aagatgctac tctgagcaag ttacaaggag atgggcgcat cacggaagaa
    18361 caggttaaag cttataatga atactatact aaaaatggag gggcaaatcg taaagtcaat
    18421 gattaaggcc tttaccatgc tggaaagtct cttggttttg ggacttgtga gtatccttgc
    18481 cttgggctta tccagctctg tccagtccac ttttgcagca gtagaggagc agattttctt
    18541 tatggagttt gaagaactct atcgggaaac ccaaaaacgc agtgtagcca gtcagcaaaa
    18601 gactagtcta aatttagatg ggcagacgct tagcaatggc agtcaaaagt tgacagttcc
    18661 taaaggaatt caggcaccat caggccaaag tattacattt gaccgagctg ggggcaattc
    18721 gtccctggct aaggttgaat ttcagaccag taaaggagcg attcgctatc aattatatct
    18781 aggaaatgga aaaattaaac gcattaagga aacaaaaaat tagggcagtg attttactgg
    18841 aagcagtagt cgctctagct atctttgcca gcattgcgac cctccttttg ggacaaattc
    18901 aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga agaagtcttg agggtagcta
    18961 agatggccct gcagacgggg caaaatcagg taagcatcaa cggagttgag attcaggtat
    19021 tttctagtga aaaaggattg gaggtctacc atggttcaga acagttgttg gcaatcaaag
    19081 agccataagg tcaaggcttt taccttgtta gaatccctgc ttgccctcat tgtcatcagt
    19141 gggggattac tcctttttca aactatgagt cagctcctca tttcagaagt tcgctaccag
    19201 caacaaagcg agcaaaagga gtggctcttg tttgtggacc aacttgaggc agaattagac
    19261 cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca tgaagcaaga tggcaaggac
    19321 atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa ccgatgctag tggacggggg
    19381 tatcagccta tggtttatgg cctcaaatca gctcagatta cagaggacaa tcaactggtt
    19441 cattttcgtt tccagtttca aaaaggctta gaaagggagt tcatctatcg tgtggaaaaa
    19501 gaagaaagtt aaggcaggtg ttctcctcta cgcagtcacc atagcagcca tctttagtct
    19561 tttgttgcaa ttttatttga accgacaaat cgcccactat caagactatg ctttaaataa
    19621 agaaaaattg gttgcttttg ccatggctaa acgaaccaag gataaagccg agcaagaaag
    19681 tggggaacag gtttttaatc taggtcaggt aagctatcaa aacaagaaaa caagcttggt
    19741 gacgactgtt cgtacgtcta agagccaata tgagtttctg tttccttcag tcaaaatcaa
    19801 agaagagaaa agagataaaa aggaagaggt agcgaccgat tcaagcgaaa aagcggagaa
    19861 aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca actataatgc
    19921 gttgaatcca gaatagtcca ctgtagtttc tagaaaattg ctggaaatgg atgttaagct
    19981 ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa ctaaagatat
    20041 gaaacatgat tttaaccaca aagcagaaac tttcgactcc cctaaaaata tcttcctcgc
    20101 aaacttggta tgtcaagcag tcgagaaaca gattgatatt ttatcagaca aagtaatttt
    20161 agatttcggt ggtggcacgg gtctattagc cttgccccta gccaagcagg ctaagtcagt
    20221 tactcttgta gacatttctg agaaaatgtt ggagcaagct cgtttgaaag tggagcagca
    20281 agcaatcaag aatatccagt ttttggagca agatttaccg aaaaatccct tggagaaaga
    20341 gtttgattgc cttgctgtta gtcgggttct tcatcatatg cctgatttgg atgcggctct
    20401 ctcactgttt catcaacatt tgaaggaaga tgggaaactc atcattgctg attttaccaa
    20461 gacagaagct aatcatcatg gatttgattt agctgaactg gaaaacaagc taattgagca
    20521 tggtttttca tctgtgcata gtcagattct ctatagcgct gaagacctgt ttcaaggaaa
    20581 tcactcagaa ttctttttaa tagtagccca aaaatcactc gcctagtcag ggagtgattt
    20641 ttctataagg atggaaaaaa gaagggaaat ttgataagat aggaatatgg attttgaaaa
    20701 aattgaacaa gcttatacct atttactaga gaatgtccaa gttatccaaa gtgatttggc
    20761 gaccaacttt tatgacgcct tggtggagca aaacagcatc tatctggatg gtgaaactga
    20821 gctaaaccag gtcaaagaca acaatcaggc ccttaagcgt ttagcactac gcaaagaaga
    20881 atggctcaag acctaccagt ttctcttgat gaaggctggg caaacagaac ccttgcaggc
    20941 caatcaccag tttacaccag atgccattgc tttgcttttg gtgtttattg tggaagagtt
    21001 gtttaaagag gaggaaatta ctatcctcga aatgggttct gggatgggaa ttctaggcgc
    21061 tactttcttg acctcgcttg ataaaaaggt ggattacttg ggaatggaaa tggatgattt
    21121 gctgattgat ctggcagcta gcatggcaga tgtaattggt ttgcaggctg gctttgtcca
    21181 aggagatgcc gttcgtccac aaatgctcaa agaaagcgat gtggtcatca gtgacttgcc
    21241 tgttggctat tatcctgatg atgccgttgc gtcgcgccat caagttgctt ctagccaaga
    21301 acatacttac gcccatcact tgctcatgga acaagggctt aagtacctca agtcagacgg
    21361 atacgctatt tttctagctc cgagtaattt gttgaccagt cctcaaagtg atttgttaaa
    21421 agaatggctg aaagaagagg cgagtctggt tgctatgatt agtctgcctg aaaatctctt
    21481 tgctaatgcc aaacaatcta agactatttt tatcttacag aagaaaaatg aaatagcagt
    21541 agagcctttt gtttatccac ttgctagctt gcaagatgca agtgttttaa tgaaatttaa
    21601 agaaaatttt caaaaatgga ctcaaggtac tgaaatataa aatagatttt gttataatag
    21661 ttgaaaacgc ttaaaaaggg gtatcatgtt atgacaaaaa caattgcaat caatgcagga
    21721 agttcaagtt tgaaatggca attatactta atgccagaag aaaaagtgtt agccaaaggt
    21781 ttgattgaac gtatcggttt gaaagattca atttcaactg taaaatttga cggccgttct
    21841 gaacaacaaa ttttggatat tgaaaatcat acacaagccg ttaaaatttt attggatgac
    21901 ttgattcgtt tcgatattat caaggcttat gacgagatta caggtgttgg acatcgtgtt
    21961 gttgctggtg gagaatattt caaagaatca acagttgttg agggagatgt tttagaaaaa
    22021 gttgaagagt tgagtttgtt ggctcctcta cacaacccgg ccaatgcagc aggtgttcgt
    22081 gccttcaagg aattgttgcc agacattacc agtgtagttg tttttgatac ttccttccac
    22141 acaagtatgc cagagaaagc ttatcgctac cctctaccaa caaaatatta cacagaaaac
    22201 aaggttcgta aatacggtgc tcatggtaca agtcaccagt ttgtagcagg agaagctgca
    22261 aaactcttgg gacgtccatt agaagacttg aagttaatta cctgtcatat tggtaacgga
    22321 ggctcaatta cagctgtgaa agccggcaaa tctgtagaca cttctatggg gttcactcct
    22381 cttggtggta ttatgatggg aacgcgtaca ggggatattg atccagctat cattccttat
    22441 ttaatgcaat atacagagga ttttaacaca ccagaagata tcagtcgtgt tcttaaccgt
    22501 gaatcaggtc ttttgggagt ttctgctaat tctagcgata tgcgcgatat agaagcagct
    22561 gtagcagaag ggaatcacga ggctagcttg gcttatgaaa tgtatgttga ccgtatccaa
    22621 aaacatatcg gtcagtactt tgcagtgcta aatggagcag atgccattgt tttcacagca
    22681 ggtgtcggtg aaaatgcaga gaatttccgt cgtgatgtaa tctcagggat ttcgtggttt
    22741 ggttgtgatg ttgatgatga aaagaatgtc tttggcgtta caggagacat ctcaacagag
    22801 gcagctaaaa tccgtgtctt ggttattcca acagatgaag aattagtcat tgcccgtgac
    22861 gttgaacgct tgaaaaaata agtgaaacta aaaaaatatt caatacaagg agttgggaaa
    22921 gttatttttc cagcttcttt ttctgatgaa attgtccaaa accttgctat gattggcttt
    22981 tttgaaaaat atggtataat agtagtaatt taatagatgg agttgagttt tgaagaaaaa
    23041 ctttcgtgta aaaagagaga aagattttaa ggcgattttc aaggagggga caagttttgc
    23101 taatcgcaaa tttgtggtct accaattaga aaaccagaaa aaccattttc gagtaggtct
    23161 atcagttagc aaaaaactgg ggaatgccgt cactagaaat caaattaagc gacggattcg
    23221 gcatattatc cagaatgcaa aagggagtct ggtagaagat gtcgactttg ttgtcattgc
    23281 tcgaaaagga gtcgaaacct tgggatacgc agagatggag aaaaatctac tccatgtatt
    23341 aaaattatca aagatttacc gggaaggaaa tgggagtgaa aaagaaacta aagttgacta
    23401 gtttgctagg actgtctctg ttaatcatga cagcctgtgc gactaatggg gtaactagcg
    23461 atattacagc cgaatcggct gatttttgga gtaaattggt ttacttcttt gcgaaaatca
    23521 ttcgcttttt atcgtttgat attagtatcg gagtggggat tattctcttt acggtcttga
    23581 ttcgtacagt cctcttgcca gtctttcagg tgcaaatggt ggcttctagg aaaatgcagg
    23641 aagctcagcc acgcattaag gcgcttcgag aacaatatcc aggtcgagat atggaaagca
    23701 gaaccaaact agagcaggaa atgcgtaaag tatttaaaga aatgggtgtc agacagtcag
    23761 attctctttg gccgattttg attcagatgc cggttatttt ggccttgttc caagccctat
    23821 caagagttga ctttttaaag acaggtcatt tcttatggat taaccttggt agtgtggata
    23881 caacccttgt tcttccgatt ttagcagcag tattcacctt tttaagtact tggttgtcca
    23941 acaaagcttt gtctgagcga aatggcgcta cgactgcgat gatgtatggg attccagtct
    24001 tgatttttat ctttgcagtt tatgcgccag gtggagtcgc cctatactgg acagtgtcta
    24061 atgcttatca agtcttgcaa acctatttct tgaataatcc attcaagatt atcgcagagc
    24121 gcgaggccgt agtacaggca caaaaagatt tggaaaatag aaaaagaaaa gccaagaaaa
    24181 aggctcagaa aacgaaataa ataaggagga atctggtaat ggtagtattt acaggttcaa
    24241 ctgttgaaga agcaatccag aaaggattga aagaattaga tattccaaga atgaaggctc
    24301 atatcaaagt catttctagg gagaaaaaag gctttcttgg tctatttggt aaaaaaccag
    24361 cccaagtgga tattgaagcg attagtgaaa cgactgttgt caaagcaaat caacaggtag
    24421 taaaaggcgt tccgaaaaaa atcaatgatt tgaacgagcc tgtgaagacg gttagtgaag
    24481 aaaccgttga ccttggtcat gtggttgatg ctattaaaaa aatagaggaa gaaggtcaag
    24541 gtatttctga tgaagtcaag gctgaaatct taaaacatga aagacatgcc agcactatct
    24601 tagaagaaac tggtcacatt gagattttaa atgaacttca aatcgaggaa gcgatgaggg
    24661 aagaagcagg cgctgatgac cttgaaactg agcaagatca aactgaaaat caagacttga
    24721 aagagatggg cttgaaggtc gagcaaagtt atgatattgc ccaggtggct acggatgtga
    24781 ctgcctatgt tcaagcgatt gtggatgaca tggatgttga agctacactt tcaaatgatt
    24841 ataaccgtcg tagcatcaat ctacaaattg acaccaacga accaggtcgt attatcggct
    24901 accatggtaa agtcttgaag gccttgcaac tgttggctca aaattatctt tacaaccgct
    24961 attccaaaac cttctacgtt acaatcaatg tcaatgatta tgtcgaacac cgtgcagaag
    25021 tcttgcagac ctatgcgcaa aaattggcga ttcgtgtttt agaagaagga cgtagtcatc
    25081 aaacagatcc aatgtcgaat agtgaacgca agattatcca ccgtattatt tcacgtatgg
    25141 atggcgtgac cagttactct gaaggtgatg agccaaatcg ctatgtcgtt gtagatacag
    25201 aataagtaaa atcagggttg acctgatttt ttgctagcta gaggaggtta aactgatgtt
    25261 gaataagata agagactatt tagactttgc tggtttgcag taccgtaatc ctgataaagc
    25321 gggagcagag cgagagaaga tgctggcatt ccgccacaaa ggacaagagg cccgaaaggc
    25381 ttttacagaa ctggccaaag cctttcaagc aagccatcca gaatggcaac tccaacagac
    25441 tagtcagtgg atgaatcagg cccagcgttt gagaccacat ttttgggttt atctacagag
    25501 agacggacaa gtgacagaac ctatgatggc cttacgtttg tatgggacat ctactgactt
    25561 tggaatttct ttggaagtca gtttcatcga acgtaagaag gatgagcaaa cactgggcaa
    25621 gcaggccaaa gttttagaca ttccaaccgt taaagggatt tattatctaa cctactctaa
    25681 tggtcaaagt caacggtggg aggcgaatga agaaaagcgt cgtactttac gcgagaaggt
    25741 gagaagtcaa gaagttcgaa aagttttagt gaaggtagat gttcctatga cagaaaattc
    25801 gtctgaagaa gaaatcgtag aaggcttatt gaagtcttat tctaaaattc ttccctatta
    25861 tctagctacg agaaaataag ataatttgta aaacatcata aatcatacag tccaagagtg
    25921 aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct ttcgcattat ataataaact
    25981 tacaaaaaca attcaaaagg agaacaatta tggaagtcgt ttcaagtgtt ctaaattggt
    26041 tttctagcaa tattttgcag aatcccgcat ttttcgtagg tttattggtg ttgataggat
    26101 atgcactttt gaaaaaacct gcccatgacg ttttttcagg gtttgttaaa gcaacagtag
    26161 ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac aacctttcgt ccaatcttag
    26221 cagctcttaa ctacaaattc caaattggtg cagcggttat cgacccttac tttggacttg
    26281 ctgcagcaaa caacaaaatt gcagcagagt ttccagattt tgttggaact gcaactacag
    26341 ctctattgat tggttttgga ataaatatct tgctcgtagc tcttcgaaag attacgaagg
    26401 taagaaccct ctttattact ggtcacatca tggtacaaca agctgcaaca gtatctctta
    26461 tggttctatt cttagtacca caattgcgca atgcttacgg tacagcagcg attggtatca
    26521 tctgtggact ttactgggca gttagttcaa atatgactgt tgaggcaact caacgcttga
    26581 ctggtggtgg cggatttgcg attggtcacc aacagcaatt tgcaatctgg tttgtagata
    26641 aagtagcagg acgctttggt aagaaagaag aaagtttaga caatcttaaa ttacctaagt
    26701 tcctctcaat cttccacgat acagttgttg catctgctac cttgatgctc gtattcttcg
    26761 gggccattct tttaatcttg ggtccagaca ttatgtctaa taaagaagtc atcacttcag
    26821 gaactctatt caatcctgct aaacaagatt tctttatgta cattatccaa acagccttta
    26881 ccttctcagt ttacttgttc gttttgatgc aaggtgtccg aatgttcgta tctgagttga
    26941 caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg ttcattccca gcggttgacg
    27001 ttgcagcttc ttatggattt ggttctccaa atgctgtctt gtcaggattt acctttggtt
    27061 tgattggtca attgattaca attgtcttgc tcatcgtctt taaaaatccg attcttatta
    27121 ttacaggatt tgtaccagtg ttctttgaca atgcagccat tgcggtctac gctgataaac
    27181 gcggcggatg gaaagcggct gttatccttt cctttatatc aggtgtcctt caagttgctc
    27241 taggagctct ttgtgtggcc cttctcgatt tggcatctta tggtggctac catggaaata
    27301 tcgactttga attcccatgg cttggatttg gatatatctt caaatacctt ggtattgttg
    27361 gttatgtact tgtgtgtctc ttcttgcttg ttattcctca acttcaattt gccaaagcaa
    27421 aagataaaga gaaatattac aacggtgaag ttcaagaaga agcttagtat ctagaaaagg
    27481 agaaataaaa tggttaaagt attagcagcg tgcggaaatg gaatgggttc atcaatggtt
    27541 atcaagatga aggttgaaaa tgctctccgt aagcttaatc aaacagattt tacagtcaat
    27601 tcatgcagtg tcggtgaagc taaaggttta gcagtaggat atgacatcgt aatcgcttct
    27661 cttcatttga ttcaagaatt ggaagggcga actaatggga agttaattgg acttgataac
    27721 ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag cactacagta aaaggttgga
    27781 gggggctgga cagaaactga gagttatcgt ttctgtcctt ctccctcttt aaataaagga
    27841 ggcagatatg aatttaaaac aagctttaat tgacaatgac tcgatccgac taggtttaga
    27901 ggctaacaat tggaaagaag cagtcaaggt agcagtagat cccttaattg aaagtggggc
    27961 aattttgcca gagtattacg atgctatcat tgaatcgact gaagagtatg ggctttacta
    28021 tatcttgatg ccaggtatgg ctatgcccca cgctagacct gaagctggtg tgcaaagtga
    28081 tgccttttca ttgattacct tacaaaatcc tgttgtattt tcagatggga aagaggtatc
    28141 tgttttgttg gcactagcag caacaagctc aaaaattcac acaagtgtag ccattccaca
    28201 aattattgcc ctgtttgaat tagaagattc tattgcacgt ttacaggctt gccagactaa
    28261 agaagatgtc ttggctatga ttgaagaatc taaggatagc ccttatctcg aaggattgga
    28321 tttggaaagt tagaaagagg aataaagaaa tgacaaaaag aatacctaat ttacaagttg
    28381 cattagacca ttcagacttg caaggagcga ttaaagcagc tgtttctgtt ggtcaggaag
    28441 tagatattat cgaagctgga actgtttgct tgcttcaagt tggaagtgaa ctggctgaag
    28501 tcttgcgtag ccttttccca gataagatta ttgtggcaga cacaaaatgt gctgatgctg
    28561 gtggaacagt tgctaaaaat aatgcggttc gtggagcaga ctggatgact tgtatctgtt
    28621 gtgcaaccat ccctactatg gaagcagctc taaaggctat caagactgaa cgaggagaac
    28681 gaggcgaaat ccagatcgag ctttatggcg attggacttt tgaacaagct cagctttggc
    28741 tagatgcagg tatctcacaa gctatttatc accaatctcg tgatgctctt cttgctggtg
    28801 aaacttgggg tgaaaaagac cttaataagg ttaaaaaact cattgacatg ggcttccgtg
    28861 tatctgtaac aggtggtcta gatgtagata ctctcaaact ctttgaaggt gttgatgtct
    28921 ttacctttat cgcaggtcgt ggaattacag aggctgcgga tccagcagga gcagcgcgtg
    28981 ccttcaagga tgaaatcaaa cgaatttggg ggtaaatcat ggtacgtcca attggaattt
    29041 atgaaaaggc aaccccaaca cactttactt ggctagaacg tttaaatttt gccaaggagt
    29101 taggctttga ttttgtcgag atgtctattg acgaacgtga cgagcgttta gcaagacttg
    29161 actggagtaa ggaagaacgc ttggaagttg tcaaagcaat ctatgaaact ggtgttcgta
    29221 ttccttctat ctgtttttca ggccatcgtc gctacccatt gggttcaaaa gatccagttc
    29281 tagaggaaaa atctctagaa ctcatgaaaa aatgtatcga attagctcaa gacttgggag
    29341 ttcgtacgat tcaattagct ggttacgatg tttactatga ggaaaagtca ccccagacac
    29401 gccaacgttt tatcaaaaat ttgagaaaag cctgtgactg ggctgaagaa gctcaggtgg
    29461 tacttgctat tgaaattatg gatgatcctt tcatcaatag catcgaaaaa tatttggcta
    29521 tagaaaaaga gattgactct cccttcctct ttgtatatcc agatattggt aatgtgtctg
    29581 catggcataa tgatatctat agtgagtttt atcttggtca tcatgccatc gcagctctcc
    29641 atctcaagga tacttatgca gtgacagaaa gttcaaaggg ccagttccga gatgtacctt
    29701 tcgggcaagg ttgtgtcaaa tgggaagaag ctttcgatat tttaaaggaa accaattata
    29761 atggaccttt cctaatcgaa atgtggtctg aaaattgtga aacagtagaa gaaacacgcg
    29821 cagccattca agaggcgcaa gcttttctct atccactcat taagaaagca ggtttgatgt
    29881 aagatgaatc aagtaatcaa tgctatgcgt aaacgagtct gtgatgccaa tcaatcattg
    29941 ccaaaacatg gacttgtcaa atttacctgg gggaatgtat ctgaagttaa tcgcgaactc
    30001 ggtgtcattg ttatcaaacc atcaggcgtg gattatgacg aattgacacc tgaaaacatg
    30061 gtagtgactg atctagatgg taagatccta gaaggggatt taagaccatc ttccgacctc
    30121 ccaactcatg tgcaattata taaggcttgg tcagaaattg gtagtgtggt tcacacccat
    30181 tcgacagaag ctgttggttg ggctcaggca ggtcgtgata ttcctttcta cggaacaacc
    30241 catgcagatt atttctacgg ttcaatccct tgcgcccgta gtttgaccaa ggacgaagta
    30301 gaagtggcct atgaaaaaga tactggcctg gttatcgtag aagagtttga acatcgcgga
    30361 cttaacccgg ttgaagtacc aggaattgtt gtacgcaatc acggtccatt cacctggggc
    30421 aaaaatccag agaatgctgt ttatcactct gtcgtactag aggaagtatc aaagatgaat
    30481 cgctttacag aacaaatcaa tccaagagtt ggacctgctc cccagtacat actagaaaaa
    30541 cactaccaac gtaaacatgg accaaatgct tattatggtc aaaagtaaga acgatgaagg
    30601 aggagaaaaa gataaattta gctcctcttt ttacatttga tttttattga gagtaaagtt
    30661 ggaattgaag taattttaaa agatttttta gaaatagcgc ttgatatata tatggtaaaa
    30721 taaaaagaat tgctgtgata tcaatagatt tgggggattt tttaatatgg tactggataa
    30781 ggcaagttgt gatttgcttc aatatttgat ggatcaagaa acgtccaaaa cgattatggc
    30841 gatttcgaaa gatttgaaag agtcaagaag gaaaatttat tatcacattg acaaaatcaa
    30901 tgctgctctg gttgacgagg cgcttcacat cattagtatt ccacgaattg gtattcactt
    30961 aacggaagag cagagagatg cttgttgtaa actattatcg gaagtagatt cgtacgatta
    31021 tatcatgagt gcgcatgaac gtatgatgat aatgttacta tggataggta tttctaaaga
    31081 acgtattacg attgaaaaat tgatagagtt aacagaggta tctaggaata ctgttctcaa
    31141 tgatttgaat agtattcgtt atcaactaac tttggaacaa tatcaggtga tcttgcaagt
    31201 gagcaagtca cagggatacc accttcatgc ccaccctctt aataaaattc agtatcttca
    31261 atcgcttcta tatcatattt ttatggaaga aaatgccact tttgtatcta ttttagaaga
    31321 taagatgaaa gagaggttag atgatgagtg tttgctttct gttgaaatga accaattttt
    31381 taaggaacag gttcctttag ttgaacaaga tttagggaag aaaataaacc atcatgaaat
    31441 aacttttatg ttgcaggttc taccttattt gctgttaagc tgtcataatg ttgaacagta
    31501 tcaagaaaga catcaggata tagagaaaga attttctttg ataagaaaaa gaatagagta
    31561 tcaggtgtct aagaaattag gagaacggtt gtttcaaaag tttgaaattt ctttgtcagg
    31621 acttgaagtt tctcttgtag ctgttctcct cctctcctat cgtaaggatt tggatattca
    31681 tgcagaaagt gatgattttc ggcaattaaa acttgcttta gaagaattta tctggtattt
    31741 tgaatcacaa atccgaatgg agattgagaa caaggatgat ttgttacgaa atttgatgat
    31801 ccactgtaaa gccttgttat ttagaaagac ttacggtatt ttttctaaaa atcctctaac
    31861 aaaacaaatt cgatccaagt atggagaatt atttttagtc actagaaaat ctgcggaaat
    31921 tttagaagga gcatggttta ttcggctaac agacgatgat attgcctatt tgacgattca
    31981 tattggagga tttttaaagt atacaccatc gtctcaaaaa aatatgaaaa aagtttatct
    32041 cgtttgtgat gaaggtgttg cggtttcgag acttttgctg aaacaatgca aactttattt
    32101 tccaaatgag caaattgaca ctgtatttac aacagaacaa tttaagagtg tggaagatat
    32161 tgcacaagtt gatgtagtga ttactactaa tgatgatttg gatagcagat ttccgatttt
    32221 aagggttaat cctatccttg aagcagaaga tattttgaaa atgctagact atcttaaaca
    32281 caatatattt cgtaataaga gcaaaagttt cagtgaaaat ctttctagtc ttatttcgtc
    32341 ttatattgta gacagcaagt tggctagtaa gttccaagaa gaggttcaaa cacttataaa
    32401 taaagaaata gtagttcaag cttttttgga agatatttga aggacagtcc aatgatgaac
    32461 acaaacctgt gtttttcttg gtctttttta gtgttttgaa gggtggtata ctaatctcaa
    32521 agataacaat tatatccaaa ggaggcaaca tatgccaaac gtcaaagaaa ttacaagaga
    32581 gtcatggatt ttagccactt tcccagagtg gggaacatgg ttgaacgaag aaatcgaaga
    32641 agaagtcgta cctgaaggca actttgccat gtggtggcta ggcaactgtg gtacttggat
    32701 taagacacca gctggtgcta acgttgtcat ggacctttgg tcaaaccgtg gaaaatcaac
    32761 caaaaaagtg aaagatatgg ttcgtgggca ccaaatggca aatatggcag gtgttcgtaa
    32821 gttgcaacca aacttgcgtg ttcagccaat ggttatcgat ccatttgcta tcaacgaact
    32881 agactattac ttagtttcac acttccacag tgatcatatc gacccataca cagctgcagc
    32941 aattctcaac aatcctaagt tagagcatgt taagtttatc ggtccttacc actgtggacg
    33001 aatctgggaa ggatggggtg ttccaaaaga acgtatcatc gttgttaaac caggtgacac
    33061 tatcgaatta aaagatatga agattcatgc agtagaatca tttgaccgta cttgcttggt
    33121 aactctccca gtgaacggtg ctgatgagac aggcggtgaa cttgctggct tggctgttac
    33181 agatgaagaa atggctcaaa aggctgttaa ctatatcttt gaaacaccag gtggaaccat
    33241 ctatcatggt gcagattctc acttctcaaa ctattttgca aaacatggta aagactttaa
    33301 aattgatgtt gctttgaata actatggtga aaatccggta ggtatccaag acaaaatgac
    33361 atctatcgat cttcttcgta tggcagaaaa tctgcgtacc aaagtcatta tcccagttca
    33421 ctatgatatc tggtctaact tcatggcttc tactaatgag attctagaac tttggaaaat
    33481 gcgaaaagat cgcttgcaat acgatttcca tccatttatc tgggaagttg gcggtaagta
    33541 cacttatcct caagatcaac acttagtaga ataccatcat ccacgtggtt ttgatgattg
    33601 ttttgaacaa gactctaaca ttcaatttaa agctttgcta taatataaaa atattctttg
    33661 gaggttatcc gtatgttgca tgatacggat aattttcata taatagtaaa atagaatgtg
    33721 tgattcaata atcacctcaa atagaaagga aattctatgt caaatctatc tgttaatgca
    33781 attcgttttc taggtattga cgccattaat aaagccaact caggtcatcc aggtgtggtt
    33841 atgggagcgg ctccgatggc ttacagcctc tttacaaaac aacttcatat caatccagct
    33901 caaccaaatt ggattaaccg cgaccgcttt attctttcag caggtcatgg ttcaatgctc
    33961 ctttatgctc ttcttcacct ttctggtttt gaagatgtca gcatggatga gattaagagt
    34021 ttccgtcaat ggggttcaaa aacaccaggt cacccagaat ttggtcatac ggcagggatt
    34081 gatgctacga caggtcctct agggcaaggg atttcaactg ctactggttt tgcccaagca
    34141 gaacgtttct tggcagccaa atataaccgt gaaggctaca atatctttga ccactatact
    34201 tacgttatct gtggagacgg agacttgatg gaaggtgtct caagcgaggc agcttcatac
    34261 gcaggtttgc aaaaacttga taagttggtt gttctttatg attcaaatga tatcaacttg
    34321 gatggtgaga caaaggattc ctttacagaa agtgttcgtg accgttacaa tgcctacggt
    34381 tggcatactg ccttggttga aaatggaaca gacttggaag ccatccatgc tgctatcgaa
    34441 acagcaaaag cttcaggcaa gccatcttta attgaagtga agacggttat tggatatggt
    34501 tctccaaaca aacaaggaac taatgctgta cacggcgccc ctcttggagc agatgaaacc
    34561 gcatcaactc gccaagccct cggttgggac tacgaaccat ttgaaattcc agaacaagta
    34621 tatgctgatt tcaaagaaca tgttgcagac cgtggcgcat cagcttatca agcttggact
    34681 aaattagttg cagattataa agaagctcat ccagaactgg ctgcagaagt agaagccatc
    34741 atcgacggac gtgatccagt cgaagtgact ccagcagact tcccagcttt agaaaatggt
    34801 ttttctcaag caactcgtaa ttcaagtcaa gatgccttga atgttgtggc agctaaatta
    34861 ccaaccttcc taggtggatc agctgacctt gctcactcaa acatgactta tatcaagacg
    34921 gatggacttc aagacgatac caatcgcttg aatcgtaaca ttcagtttgg tgttcgtgaa
    34981 tttgcaatgg gaacaatctt gaacgggatg gcccttcatg gtggacttcg tgtatacggt
    35041 ggaactttct tcgtcttctc tgactatgtg aaggcagctg tccgcttgtc agccttacaa
    35101 ggacttcctg tgacttatgt ctttacccat gattcaatcg cagttgggga agatggtccg
    35161 actcacgaac cagttgagca tttagcaggt cttcgtgcta tgccaaatct aaatgttttc
    35221 cgtccagcag atgcgcgtga aacgcaagca gcttggtacc ttgcagtgac aagtgagaaa
    35281 acaccaactg cccttgtctt gacacgtcaa aacttgactg ttgaagatgg aacagacttc
    35341 gacaaggttg ctaaaggtgc ttatgttgta tatgaaaatg cagccgactt tgataccatc
    35401 ttgattgcga caggttcaga ggttaatctt gctgtctcag ctgctaaaga attggctagt
    35461 caaggcgaaa aaatccgcgt agtcagcatg ccatctacag atgtctttga taaacaagat
    35521 gcagcttaca aggaagagat tcttccaaat gcagtccgcc gtcgtgttgc agtcgaaatg
    35581 ggtgcaagtc aaaactggta caaatatgtt ggtctcgatg gtgccgttct aggtattgat
    35641 accttcggag cctctgcccc agcaccaaaa gtattggcag aatatggctt tactgtagaa
    35701 aatcttgtaa aaattgttcg aaacttgaaa taatcctaaa aatcagggcg taagctctgg
    35761 tttttcttac cagaaaagta aggtacaatc ttgtaaaagt agctgaaatt tgatatagta
    35821 gtcctatgta aaagacaaag gagaaaacaa tgaatccaaa tattactttt ttaatcatgc
    35881 ttgtaggtat gatggccttg atgttcttta tgcaacgttc tcaaaagaaa caagctcaaa
    35941 agcgtatgga aagcttaaat aaactacaaa aaggctatga agtgattaca atcggtggac
    36001 tttatggaac agtcgatgaa gtagatacgg agaagggaac aatagttctt gacgtagatg
    36061 gagtttactt gacttttgaa ctagctgcta tcaagacagt attaccgctg aaagaaacag
    36121 cttcactaga aggcgcaatt gaaaaataag acgggatcac gaactcccgt ttttctataa
    36181 aagaaaggaa atgggatgaa aaaattagtc tttgtctgtc tgggaaatat ttgccgtagc
    36241 cctatggccg agtttgttat gaaatcaatg acagataact acgaaatcca aagtcgagca
    36301 acttcctctt gggaacatgg caatccgatt cataagggga ctcagggaat ttttcaagag
    36361 tatgagattc cttatgacaa gaacaagaca tcgcttcaga ttagtaagga agattttgaa
    36421 gcctttgatt atattatcgg aatggacgct tcaaatattt ctgacttatg tcagatgtgt
    36481 ccagtagact gtcaagataa gatttactca ttttcatctg aaagtgttcc agacccttgg
    36541 tatacaggag attttgaaga aacctatcga cgtgttcaag agggctgtca agcttggtta
    36601 gaacgtttag aaaaggagag ttaaggtgga aaatcttacg aatttttacg aaaagtatcg
    36661 tgtctatctg actcgtccac gtttagagct tttggcagta gttaccattg ttttttgtgc
    36721 tgtactcgtc ttttttctaa atattccagg aaaaggtgtc ttaaaactcg ataatggaac
    36781 gattgtttat gatggcagtc ttgtccgtgg taaaatgaat ggccaaggta ccattacctt
    36841 ccaaaatgga gaccaatata caggtggctt caacaatgga gccttcaacg gaaaaggtac
    36901 ctttcaatct aaagaaggct ggacctacga aggtgatttt gtaaatggtc aggctgaagg
    36961 aaaagggaaa ctaacaacag aacaagaagt cgtttatgaa ggaactttta aacaaggcgt
    37021 ttttcaacaa aaataaagcc tccttatcaa aggaggtatt attagaatca caaggtaagc
    37081 gcttacctgt aaatcccttt ctttccaaat ccctcttcca agcaagtttg tgaaataaaa
    37141 aatatttgaa ataaatttca caaacttcaa agataaaact tgataagaaa agaaaatgag
    37201 aaaagtttca caagagttta aaaattcttt gtgaaatgtt tatgaaactg tttacaaagt
    37261 tgaaataatg cgttataata aacttgtgaa aaaattaaca aaggatatcg ttccttgaaa
    37321 gctatggagg aaaatatggc tgataaaaaa actgtgacac cagaggaaaa gaaactcgtt
    37381 gctgaaaaac acgtagatga gttggttcaa aaagctctag ttgcccttga agaaatgcgt
    37441 aaattggatc aagaacaagt tgactacatc gttgccaaag catcagtagc agctttggat
    37501 gcccacggag aattggcttt acatgccttt gaagaaacag gacgtggtgt atttgaagac
    37561 aaagcaacta agaacttgtt tgcttgtgaa cacgtagtaa acaatatgcg ccacactaag
    37621 acagttggcg ttatcgaaga agacgatgta acaggattga ctcttattgc tgaaccagtt
    37681 ggtgttgttt gtggtattac tccaacaaca aacccaacat caacagcaat cttcaaatca
    37741 ttgatttcat tgaagacacg taacccaatc gtctttgcct tccatccatc agcacaagaa
    37801 tcatctgctc atgcagctcg tatcgtccgc gatgcagcta tcgcagctgg tgctcctgaa
    37861 aactgtgtgc aatggattac tcaaccatct atggaagcaa caagtgccct tatgaaccac
    37921 gaaggtgttg cgacaatcct tgcaacaggt ggtaatgcca tggttaaggc ggcttattca
    37981 tgtggtaaac cagctcttgg ggtaggtgcc ggaaacgttc cagcttatgt tgaaaaatca
    38041 gcaaacattc gtcaagcagc acacgatatc gtcatgtcta aatcatttga taacggtatg
    38101 gtctgtgcat ctgaacaagc agttatcatt gataaagaaa tttacgatga atttgtagca
    38161 gagttcaaat cttaccacac ttactttgta aacaaaaaag aaaaagctct tcttgaagag
    38221 ttctgcttcg gcgtcaaagc aaacagcaaa aactgtgctg gtgcaaaatt gaacgctgac
    38281 atcgttggta aaccagcaac ttggattgca gaacaagcag gatttacagt tccagaagga
    38341 acaaacattc ttgctgcaga atgtaaagaa gttggcgaaa atgagccatt gactcgtgaa
    38401 aaattgtcac cagttattgc agttttgaaa tctgaaagcc gtgaagatgg tattactaag
    38461 gctcgtcaaa tggttgaatt taacggtctt ggacactcag cagctatcca cacagctgac
    38521 gaagaattga ctaaagaatt tggtaaagct gttaaagcta ttcgtgttat ctgtaactca
    38581 ccttctactt ttggtggtat cggggacgtt tacaatgcct tcttgccatc attgacactt
    38641 ggatgtggtt cttacggacg caactcagtt ggggataacg ttagtgccat taacctcttg
    38701 aatatcaaaa aagtcggaag acggagaaat aacatgcaat ggatgaaact tccttcaaaa
    38761 acatactttg aacgtgattc aattcaatac cttcaaaaat gtcgtgacgt tgaacgtgtc
    38821 atgatcgtta ctgaccatgc catggtagag cttggtttcc ttgatcgtat catcgaacaa
    38881 ctggaccttc gtcgcaataa ggttgtttac caaatctttg cggatgtaga accggatcca
    38941 gatatcacaa ctgtaaaccg tggtactgag attatgcgtg ccttcaaacc agataccatc
    39001 atcgcactcg gtggtgggtc tccaatggat gctgccaaag taatgtggct cttctacgag
    39061 caaccagaag tggacttccg tgaccttgtc caaaaattca tggatatccg taaacgtgcc
    39121 ttcaagttcc cattgcttgg taagaagact aaattcatcg cgattccaac tacatctggt
    39181 acaggatctg aagtaacacc atttgccgtt atctctgata aagcaaacaa ccgtaaatac
    39241 ccaatcgctg actactcatt gacaccaact gtggcaatcg tagatcctgc tttggtattg
    39301 acagttccag gatttgttgc tgctgatact ggtatggacg tattgactca cgcgacagaa
    39361 gcatacgtat cacaaatggc tagtgactac actgatggtt tagcacttca agccattaaa
    39421 ttggtctttg aaaatctcga aagctcagtt aagaatgcag acttccactc acgtgagaaa
    39481 atgcataacg cttcaacaat cgctggtatg gcctttgcca atgccttcct aggtatttct
    39541 cactcaatgg cccataagat tggtgcgcaa ttccacacaa tccacggtcg tacaaatgct
    39601 atcttgcttc catacgttat ccgttacaac ggtacacgtc cagctaagac agcaacatgg
    39661 cctaagtaca actactaccg tgcagatgaa aaataccaag atatcgcacg catgcttgga
    39721 cttccagctt ctactccaga agaaggggtt gaatcttacg caaaagctgt ctacgaactc
    39781 ggtgaacgta ttgggatcca aatgaatttt agagaccaag gaattgacga aaaagaatgg
    39841 aaagaacatt ctcgtgaatt agccttcctg gcttatgaag accaatgttc accagctaac
    39901 ccacgtcttc caatggtaga ccatatgcaa gaaatcatcg aagatgcata ctatggctac
    39961 aaagaaagac caggacgccg taaataattg tttatcagtc tagaagcaag acaaaaactc
    40021 aatttgaggg aaagatccag taatttttct atgataaaag gcatcctatc aaggtttttg
    40081 aacacctgat aggatgcctt tttatgatat tgaggccttt ttgccctttt tgaaaaacta
    40141 gaatagaaac aaaatatata atagattgaa actggaatag tacacttctg cttctaaaac
    40201 attgttagaa ttcgatttga ctgtcctgat cgatt
//
LOCUS       DAVKBK010000015        39107 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVKBK010000015 DAVKBK010000000
VERSION     DAVKBK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.015"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(73..882)
                     /locus_tag="VWX69_000831"
     CDS             complement(73..882)
                     /locus_tag="VWX69_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9192203.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(884..1687)
                     /locus_tag="VWX69_000832"
     CDS             complement(884..1687)
                     /locus_tag="VWX69_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9192204.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1697..3184)
                     /gene="tacF"
                     /locus_tag="VWX69_000833"
     CDS             complement(1697..3184)
                     /gene="tacF"
                     /locus_tag="VWX69_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU9192205.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIIKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3520..4227
                     /locus_tag="VWX69_000834"
     CDS             3520..4227
                     /locus_tag="VWX69_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU9192206.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4232..5254
                     /locus_tag="VWX69_000835"
     CDS             4232..5254
                     /locus_tag="VWX69_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9192207.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5271..6140
                     /gene="licA"
                     /locus_tag="VWX69_000836"
     CDS             5271..6140
                     /gene="licA"
                     /locus_tag="VWX69_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU9192208.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            6130..7008
                     /locus_tag="VWX69_000837"
     CDS             6130..7008
                     /locus_tag="VWX69_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU9192209.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7020..7709
                     /locus_tag="VWX69_000838"
     CDS             7020..7709
                     /locus_tag="VWX69_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU9192210.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7805..8653
                     /gene="dprA"
                     /locus_tag="VWX69_000839"
     CDS             7805..8653
                     /gene="dprA"
                     /locus_tag="VWX69_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU9192211.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9542..10585
                     /locus_tag="VWX69_000840"
     CDS             9542..10585
                     /locus_tag="VWX69_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU9192212.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10752..12839
                     /gene="topA"
                     /locus_tag="VWX69_000841"
     CDS             10752..12839
                     /gene="topA"
                     /locus_tag="VWX69_000841"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU9192213.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            12945..13304
                     /locus_tag="VWX69_000842"
     CDS             12945..13304
                     /locus_tag="VWX69_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU9192214.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13397..14029
                     /locus_tag="VWX69_000843"
     CDS             13397..14029
                     /locus_tag="VWX69_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU9192215.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            14073..14729
                     /locus_tag="VWX69_000844"
     CDS             14073..14729
                     /locus_tag="VWX69_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU9192216.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14748..15380
                     /locus_tag="VWX69_000845"
     CDS             14748..15380
                     /locus_tag="VWX69_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU9192217.1"
                     /translation="MNFQLAKYSLLKKFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     CSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            15408..15842
                     /locus_tag="VWX69_000846"
     CDS             15408..15842
                     /locus_tag="VWX69_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU9192218.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15854..16891
                     /gene="leuB"
                     /locus_tag="VWX69_000847"
                     /pseudo
     CDS             15854..16891
                     /gene="leuB"
                     /locus_tag="VWX69_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            16888..17157
                     /locus_tag="VWX69_000848"
     CDS             16888..17157
                     /locus_tag="VWX69_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU9192219.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17161..17520
                     /gene="leuD"
                     /locus_tag="VWX69_000849"
     CDS             17161..17520
                     /gene="leuD"
                     /locus_tag="VWX69_000849"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU9192220.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17682..18305
                     /locus_tag="VWX69_000850"
                     /pseudo
     CDS             17682..18305
                     /locus_tag="VWX69_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            18471..20402
                     /locus_tag="VWX69_000851"
     CDS             18471..20402
                     /locus_tag="VWX69_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU9192221.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSINSRQNLSVNYDSGVSGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            20389..21705
                     /locus_tag="VWX69_000852"
     CDS             20389..21705
                     /locus_tag="VWX69_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU9192222.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFFHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            21880..22866
                     /locus_tag="VWX69_000853"
     CDS             21880..22866
                     /locus_tag="VWX69_000853"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU9192223.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCVKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            22930..23001
                     /locus_tag="VWX69_000854"
     tRNA            22930..23001
                     /locus_tag="VWX69_000854"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22963..22965,aa:Arg,seq:ccg)
     gene            23184..23882
                     /locus_tag="VWX69_000855"
     CDS             23184..23882
                     /locus_tag="VWX69_000855"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU9192224.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            23873..27412
                     /gene="smc"
                     /locus_tag="VWX69_000856"
     CDS             23873..27412
                     /gene="smc"
                     /locus_tag="VWX69_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU9192225.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSHQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            27409..28203
                     /locus_tag="VWX69_000857"
     CDS             27409..28203
                     /locus_tag="VWX69_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9192226.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            28203..29021
                     /locus_tag="VWX69_000858"
     CDS             28203..29021
                     /locus_tag="VWX69_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9192227.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            29025..30302
                     /gene="ftsY"
                     /locus_tag="VWX69_000859"
     CDS             29025..30302
                     /gene="ftsY"
                     /locus_tag="VWX69_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU9192228.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(30348..31835)
                     /locus_tag="VWX69_000860"
     CDS             complement(30348..31835)
                     /locus_tag="VWX69_000860"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU9192229.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWD
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(31984..32724)
                     /locus_tag="VWX69_000861"
     CDS             complement(31984..32724)
                     /locus_tag="VWX69_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9192230.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(32724..34889)
                     /locus_tag="VWX69_000862"
     CDS             complement(32724..34889)
                     /locus_tag="VWX69_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9192231.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            35062..36015
                     /locus_tag="VWX69_000863"
     CDS             35062..36015
                     /locus_tag="VWX69_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9192232.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLQQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSSLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            36092..38080
                     /gene="uvrB"
                     /locus_tag="VWX69_000864"
     CDS             36092..38080
                     /gene="uvrB"
                     /locus_tag="VWX69_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU9192233.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            38090..38653
                     /locus_tag="VWX69_000865"
     CDS             38090..38653
                     /locus_tag="VWX69_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192234.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            38619..39107
                     /locus_tag="VWX69_000866"
     CDS             38619..39107
                     /locus_tag="VWX69_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192235.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
BASE COUNT        12175 a         6827 c         8490 g        11615 t
ORIGIN      
        1 tgtatttcat tttctactaa aattatgttt ttgaataacc tctatcttag tagtttgtat
       61 aatccccctc aatcagtttt tgcgataagc tttaatgcta tgactatacc actcttgcat
      121 ttcttttgat ggtggtgtca tataatcgcc atacatctgg gttaaaaatt ggtcatattt
      181 tttgggaaca ggcaacatac ggccctcaaa ctcagttaaa atcagttctt taaaggtatc
      241 aactgggaag atttctttca tcccttcctt accgatccca actcctcctt catattgagg
      301 aatgttggtt acagcatttt tgactagttg atcaattttc ttgtaaaagt agcgaggatt
      361 gacaaatcgg agagcgtacc agctacataa tctaagaaaa tcttttagtt tgctatcacc
      421 gtgaactgct cgtgattttt tgatataagc tagttgacga agagccacat acttatagct
      481 cttgtcgaca atgctcaagt ctgtaaatcg atcaattggg aagacatcga tgaaaaggct
      541 ggtatcatga cgcttgtact taacatggtc ttctataaca gtagaagtgt ccaaaatcga
      601 tgcgaaatta tggaagtacc aagaagatgt atcgtaggaa agaaccttgt agcgagggtg
      661 attttcttct tcaataatct tcagtaaacg ctcataatcc tcacgataaa gggaaatatc
      721 aatatcatca tcccaaggaa tcataccttt gtggcggatg gctccaagca tggttccata
      781 actgagaaaa taaggaatat catgtttctt acaagtctca tcaatatagt ccagcagggc
      841 tagttgaatt tctttaattt cttttttttc taaatattgc atcctaatcc tccaatttat
      901 aagcgtgaaa ttcatgactg tagaagcgtt tttcttctgg tggtagggtc atataatctc
      961 cataaaattg tgtcaaaata gtatcaaatt tttcaggtgc aggaaggctt aaattctcaa
     1021 agggtaaatc gattgtttta tcaaaggtac cacttgggaa gacttccttt tccttaaatt
     1081 ttgaagggat aaaagccata tactgcccat tttcacgact atatttttga atttctttct
     1141 cgattttatt tgcaaaataa cgaggagaaa ctggtcgaag gagcaaccaa aaggctgttc
     1201 gtatccaatc ttttaaaagg ctatccttat agacaatatt tttatgttta ctgaaagaca
     1261 gcagtttgaa gctttccagt ttataacaag tatcaatgac cttaggatca tcaaagcgat
     1321 ccatagggaa aatatcgata aagataccag actcataggt ttttgtattt cgagtatcaa
     1381 taattttagt cgtactgtcg gttatcttga taaagttgtt aaagtagttc ttatcagttt
     1441 ctaaggatag gagttcatac ttgctttttt ccttttgaaa aatgttaata aatcgttggt
     1501 agtcttctct aggcatggat aaatcaatat cgtcgtccca agggataaag ccctcatgtc
     1561 gaaccgcccc aatcagagta ccgtagttaa taatatagtt gatattgtgc tttttacaga
     1621 gagtatcaat ataatccaaa atttctaatt caatttgttt ggcatcttca acggttagtt
     1681 gtttcatttt aaactcctat gattttttaa atttattttt taaggctaga acatggttta
     1741 aaaattcata gaaaatgcta tcttttgtga agacaagtag actaatataa gagatagctg
     1801 atagcaagat aatcaaacca gtattaatca aaaatggcaa attaatgacc atatccacag
     1861 gatacacgaa attaatcagg aaataaattg ctacaaagga aagtgaaaag agagagtatc
     1921 gaacagtata gctaaagata tgtcccaagt ggatgagttg ttttctatgg atgaaaatga
     1981 tatagaaaac aagtagagaa gcctctgata acatagttgt cagtaagtag tattcgggag
     2041 ccacgatacg gttgaaaaag aggagactat tcaagcccaa attgagtagc ccagcaaaga
     2101 ctgtataaac tgtgatacgt ttttcatagc cattggtaaa gagaatttgg gaaccaagaa
     2161 tggtatctaa ggccaggata atcgtacgaa aagcgaagag agaggtcaag atgccgcctc
     2221 cgatatattt ttcactaccg taaagtagga tggcatttgg tcctaaaacc atgagtccaa
     2281 aactcagtgg aatgataaag aagttaaaga ttcgactacc tctattaacc agagaaacat
     2341 aggcttcttt gtctcctttc cccagatagt aactgagacg aggcacactc actccaattg
     2401 cacctgttac aaccccagct ataacggtca caattcgctg agctatggta tagtaactaa
     2461 cgttgacatc aatccctgtt ttaacgagga agaggcgatc taaaaaagtg aagagcatat
     2521 tggcattggc aaagactaac atggctgtca gagggagaaa gagtggttta aaatcactta
     2581 ggtgaatctt aacaagtttg atgtctcttt taatccaaaa ataactaatc aggtagttaa
     2641 tcagcgtcga taaactcatc acaagtgtat agacaacaat atcgtgttca tttttaacaa
     2701 ataagaaaat agagaccagc atcaggatac ggatgaaggc agttttgtaa aagagaaaac
     2761 tgtaattttc cagagcttca ttgacccatt cgattgaaaa aatctgggca atgagttgaa
     2821 tccccataac aaggtagacc tttttgatga ttggattatc agtaaagaag agaggatagg
     2881 ctaggatata gacagcagtg gtcaaaatcg tacaagcgat gcacaaataa aaaagactag
     2941 aaaaggttct gttaagatct tttttgttat ccttgacatt actgatagcc cttaaaccgt
     3001 agttatagac accataagtt gcaaagggca agaaaaatga caaaatagtg tcgactgagt
     3061 tgaagtaacc atagtcagtt cggtccaaga cacgcgcgac ataggttcca gttaggatgg
     3121 gaaaaataat attcaagaca cgaattccca tgtaagatag agcatttaat tttatacttt
     3181 tcattcaatt tacctcgttt ttcattatat cataaagtta gctaataaga aatgaagggc
     3241 agtaagccaa gcaatcactt tgaagtttca aatcttaaat tttaagtttt ctttaaggaa
     3301 agtatattat tctgaaggac tctaaaattt cgcagtcatt tattagtaat tgctacagaa
     3361 ttcctagtca ttactagaaa tggactagtt tctttgaata atagaactgc ataattctcc
     3421 tattctagaa ggggaggacc agtatttctt ttatgatagg actagattgt ggtataatag
     3481 agagaataag tttttttagt aagacaaagg agaaaataga tgatttatgc aggaattctt
     3541 gccggtggaa ctggcacacg catggggatc agtaacttgc caaaacaatt tttagagcta
     3601 ggtgatcgac ctattttgat tcatacaatt gaaaaatttg tcttggagcc aagtattgaa
     3661 aaaattgtag ttggtgttca tggagactgg gtttctcatg cagaagatct tgtagataaa
     3721 tatcttcctc tttataagga acgtatcatc attacaaagg gtggtgctga ccgcaataca
     3781 agtattaaga aaatcattga agccattgat gcttatcgtc cgcttactcc agaggatatc
     3841 gttgttaccc acgattctgt tcgtccattt attacacttc gcatgattca ggacaatatc
     3901 caacttgccc aaaatcatga cgcagtggac acagtggtag aagcagttga tactatcgtt
     3961 gaaagtacca atggtcaatt tattacagat attccaaatc gtgctcacct ttatcaagga
     4021 caaacacctc aaacattccg ttgcaaggac ttcatggacc tttatggatc tctttctgat
     4081 gaagagaagg aaatcttgac agatgcatgt aaaatctttg tgatcaaagg aaaagatgtg
     4141 gccttggcca aaggtgaata ctcaaatctg aagattacaa ccgtaacaga tttgaagatt
     4201 gcaaaaagta tgattgagaa agactagtaa aatgattaat caaatttatc aactaactaa
     4261 gcctaagttt atcaatgtca aatatcagga agaggctatt gaccaagaga atcatatcct
     4321 tatccgtccc aactacatgg ctgtctgtca tgcggatcag cgttactatc agggaaaacg
     4381 tgatcccaag attttgaata aaaagcttcc aatggcaatg attcacgagt catgtggaac
     4441 cgtcatttct gacccgaccg gaacctacga ggttggtcaa aaagttgtca tgattcccaa
     4501 tcagtctcct atgcagagtg atgaagaatt ctatgaaaac tacatgacag ggacccattt
     4561 cttgtctagt ggatttgatg gctttatgag agagtttgtt tctctcccta aagatcgtgt
     4621 ggtggcttat gatgctattg aagatacggt tgcagccatt acagagtttg tcagtgtggg
     4681 catgcacgct atgaatcgtc tattgactct tgctcatagc aagcgggagc ggatcgccgt
     4741 tattggagat ggaagtttag cttttgtggt tgccaatatt atcaactata ctttgccaga
     4801 atcagagatt gtggttattg gtcgtcattg ggaaaagttg gaactcttct catttgccaa
     4861 agaatgctat attacggata atattcctga agagttggcc tttgaccatg cttttgaatg
     4921 ttgtggtggt gatggtactg gaccagctat taatgacttg attcgctaca ttcgtcctca
     4981 gggaacgatt ctcatgatgg gagttagcga atataaagtc aatctcaata ctcgcgatgc
     5041 cttagaaaag ggcttgattt tggttgggtc atctcgttct ggtcgcattg attttaaaaa
     5101 tgctatccaa atgatggaag tcaagaaatt tgccaatcgt cttaaaaata tcctttatct
     5161 agaagaacct gtaagagaaa ttaaagatat tcatcgtgtc tttgcaaccg atttaaacac
     5221 agcctttaaa acagtgttta agtgggaagt ataagtactg gaggttaatt gtggagaaaa
     5281 tcattaaaga aaaaatttct tccttactta gtcaagaaga ggaagtcctc agtgttgaac
     5341 aactgggtgg aatgaccaat caaaactatt tggccaaaac aacaaataag caatacattg
     5401 ttaaattctt tggtaaaggg acagaaaagc ttatcaatcg acaagatgaa aagtacaatc
     5461 ttgaactact aaaggattta ggcttagatg taaaaaatta tctttttgat attgaagctg
     5521 gtatcaaagt aaatgagtat atcgaatctg cgattacgct tgattcaacg tcaatcaaga
     5581 ccaagttcga caaaattgct ccaatattac aaactattca tacgtctgct aaggaattaa
     5641 gaggagaatt tgctcctttt gaagaaatca aaaaatacga atccttgatt gaagaacaaa
     5701 ttccttatgc caactatgaa tctgttagaa atgcagtctt ctccttagag aaaagactgg
     5761 ctgacttagg tgttgacaga aaatcttgtc atatcgattt ggtgcctgaa aactttatcg
     5821 aatcacctca aggacgactt tatttgattg actgggaata ttcatcaatg aatgatccaa
     5881 tgtgggattt ggctgccctc tttttagagt ctgaattcac ttcccaagag gaagaaactt
     5941 tcttatctca ctatgagagt gaccaaacac cggtttctca tgaaaagatt gctatttata
     6001 aaattttaca agatactatt tggagtctat ggactgtcta taaggaagag caaggtgaag
     6061 attttggtga ctatggtgtg aatcgttacc aaagagctgt taaaggtttg gcttcttatg
     6121 gaggttcaga tgaaaagtaa aaacggagtt ccttttggcc ttctctcagg tattttctgg
     6181 ggcttgggtc taacggttag tgcttatatc ttttcgattt ttacagattt gtcacccttt
     6241 gtggtggctg cagctcatga ttttttgagc atctttatct tactagcttt tctcttggta
     6301 aaagaaggga aagttcgcct ctcaattttc ttaaatattc gcaatgtcag tgttatcatc
     6361 ggagccttgc tagcaggccc tatcggtatg caggccaatc tttatgcagt taagtatatc
     6421 ggaagttctt tagcttcatc tgtatcggct atttaccctg cgatttcagt tctattggct
     6481 ttcttctttt tgaagcacaa gatttcgaaa aatactgtat ttgggattgt cttgattatt
     6541 ggagggatta ttgctcagac ctataaggtt gaacaggtta attctttcta cattgggatt
     6601 ctttgtgctt tggtttgtgc tattgcatgg ggaagtgaga gtgttcttag ctcttttgcc
     6661 atggaaagtg aattgagtga aatcgaagcc ctcttaatcc gtcaagtaac ttcgttcttg
     6721 tcctatcttg tgattgtgct cttctctcat cagtcattta ctgcagtagc caatggacaa
     6781 ttgctaggtc tcatgattgt ttttgcagcc tttgatatga tttcctactt ggcttattat
     6841 atcgctatca atcgcttgca accagccaag gctacaggct tgaacgtgag ctatgtagta
     6901 tggacggtct tgtttgcagt tgttttcttg ggtgcaccgc tagatatgct gaccattatg
     6961 acgtcacttg tcgtcattgc tggagtttat attattatta aagaataaag gagattcgtg
     7021 tgaaagccat tatcttagca gcgggattgg gaactcgctt gcgtcctatg actgaaaata
     7081 cccctaaagc cttggttcag gttaatcaaa aacctttgat tgagtaccaa attgagtttc
     7141 tcaaagaaaa aggaatcaat gacatcatca tcattgttgg ttatcttaaa gaacaattcg
     7201 attacttgaa agagaaatac ggtgttcgtc tcgttttcaa tgataaatac gctgactaca
     7261 ataactttta ctctctctat cttgtaaaag aagaattggc caacagctat gttattgatg
     7321 ctgacaatta tctctttaaa aatatgttcc gcaatgattt gacacgttcg acttatttta
     7381 gtgtttatcg tgaagattgt accaacgaat ggttcttggt ttatggagat gactacaagg
     7441 ttcaagacat tattgttgat agcaaggcag gtcgcatcct tagtggtgta tccttctggg
     7501 atgctccaac tgcagaaaag attgtcagct ttatcgacaa ggcttatgta agtggtgaat
     7561 ttgttgatct ctattgggac aatatggtta aggataatat caaagagcta gatgtctatg
     7621 ttgaagaatt agaaggcaat agcatttatg agatcgatag tgtccaagac tatcgtaaat
     7681 tagaagaaat tcttaaaaac gaaaattaaa gattccaaca tctgacaaaa tagtcggatg
     7741 ttttttgatt ttttacgaac ttttacgaat agatagatga gtagaaaaag aaatggagtt
     7801 atttatgaaa atcacaaact atgaaatcta taagttaaaa aaatcaggtt tgaccaatca
     7861 acagattttg aaagtgctag aatacggtga aaatgttgat caggagcttt tgttgggtga
     7921 tattgcagat atctcaggtt gccgtaatcc agccgttttt atggaacgtt attttcagat
     7981 agacgatgcg catttgtcga aagagtttca aaaatttcca tctttctcta ttttagatga
     8041 ctgttatcct tgggatttga gtgaaatata tgatgcgcct gtacttttat tttacaaggg
     8101 aaatcttgac ctcctgaaat tcccgaaggt agcggtcgtg ggcagtcgtg cttgtagcaa
     8161 acagggagct aagtcagttg aaaaagtcat tcaaggcttg gaaaatgaac tggttattgt
     8221 cagtggtctg gccaagggca ttgacacagc agctcatatg gcagctcttc agaatggcgg
     8281 aaaaaccatt gcagtgattg gaacaggact ggatgtgttt tatcctaaag ccaataaacg
     8341 cttgcaagac tacatcggca atgaccatct ggttctaagt gaatatggac ctggtgaaca
     8401 acctctgaaa tttcattttc ctgcccgtaa tcgcatcatt gctggacttt gtcgtggtgt
     8461 gattgtagca gaggctaaga tgcgttcagg tagtctcatt acgtgtgagc gagcaatgga
     8521 agaaggacgc gatgtctttg ctattcctgg tagcatttta gatggactat cagacggttg
     8581 ccatcatttg attcaagaag gagcaaaatt agtcaccagt gggcaagatg ttcttgcgga
     8641 atttgaattt taaaaatgac ctaagctaga attctaagaa aaaatcaatt ttaagagaaa
     8701 atgaacccaa catttccata ataaaacgca tattagcaag tttttaacac ttgataatat
     8761 gcgttttttc taagtggatt agtagagtag aggatttttc tcatataata ctcttcgaaa
     8821 atctcttcaa actacgtcag cttccatctg caacctcaaa acagtatttt gagctgactt
     8881 cgtcagtctt atctacaacc tcaaagcagt gctttgagca acctgtggct agcttcctag
     8941 tttgcgcttt gattttcatt gagtataagg gaaagtatag tgaattgaaa taagatgtga
     9001 acaactctat caggaaagtc aaattgattt atagaaatat tttagcagcc aaggtgcact
     9061 gttatagatt caatacacta taatttagtg taattgagaa aggagaaatg attgtgattg
     9121 atgttggcta ggttatgttc aatgattcct accgtctcaa atcttgtcag taaggaaaaa
     9181 taaattcttc aaaagtagag attacaaggc ttgtttaaga aagaattcaa agaccttgac
     9241 aaataaaaat aaaatggtta ttataaaaaa tggtctgaaa tagatgatga tacttttcga
     9301 aaatctcttc aaactacgtc agctcagctt tgccttgctg tgttttgagc aagctacggt
     9361 tagcttccga gtttgatttt catttactag aaatgaaact gatgagagat atcagtagac
     9421 atttgagtca ggatattatg gaaaatgata aaaagagctc gtgagattgg catatcagac
     9481 tactaaagta ttgagtttgt taggatttta gcgactagtt agctgggaaa ggaagatatt
     9541 tgtgacaaat aataaactgt attcgttgat agaatttaga aataaaatat atgaagaatt
     9601 agaactttcc agaagtgatt tagcgatttt actatgtgcc atgcttatcg cctctatcgg
     9661 attaaatatg gattcgactc ccgtgattat tggagccatg ttaatctctc ctttgatgac
     9721 acctattctg ggagtggggc tctctctagc tatatttgat tttaaattgt taagaaaatc
     9781 ttttaaaata ttagctattc aaattcttgc cagtctaata gcttcaacac tttattttta
     9841 tctttctccc atttcgtatg ctagttcgga gattgttgct agaacctctc cgactatttg
     9901 ggatgttctc attgcttttg taggagggat agcaggtatt attggtgcta ggaaaaaaga
     9961 gaccaataat attgttcctg gtgttgctat tgcaaccgcc ttgatgcctc ctctttgtac
    10021 agtaggttat gctattgctt ctgctaatct aaaatttatc ataggctcct cttacctatt
    10081 cctcatcaat tgtagcttta ttgtcattgc gacttatata ggtgttaggt tgatgatggt
    10141 taagaaacat tattttaaag ataatgaaga agactctaaa atgcgtagga ttttgcttct
    10201 agttgctgtt ttgctgatga ttccgagttt catctctgca acgactttag tgagagaaac
    10261 gttgaaaaaa gagtccctta agaaatttat atcagagcag tttcaggggt ataatatttt
    10321 gaaaaaaacc tattctaaaa agactcatac cctaaagcta accatttcag gaaattattt
    10381 gacagaagaa gaactcgata tgatttcaag taagagaggt gactatggtt taagtgatgt
    10441 ttctgttcaa gtttcacaat tgtctgattc agaacaactt agtaaggaag agctggtgga
    10501 gtatttcttc cagtatatca aggataagga agcaaaagaa aaggagaaag ccaataaatt
    10561 tgatacagag tctgaggagc aataatttct tgagaatagc tggtttctct cgtgagtctt
    10621 ctatgtatat caaaggaaga ctgaggtttt aagtataaaa cttttcttct attatagtag
    10681 ctaagtcttg acagggttca aaaaatggtt tacactttat aaagtttatt actttgaaaa
    10741 ggtgtgatac tgtggctacg gcaacaaaaa agaaaaaatc aacagttaaa aaaaatctag
    10801 tcatcgtgga gtcgcctgct aaggccaaga cgattgaaaa atatctaggc agaaactaca
    10861 aggttttagc cagtgtcggg catatccgtg atttgaagaa atccagtatg tccgtcgata
    10921 ttgaaaataa ttatgaaccg caatatatta atatccgagg aaaaggccct cttatcaatg
    10981 acttgaaaaa agaagctaaa aaagctaata aagtttttct cgcgagtgac ccggaccgtg
    11041 aaggagaagc gatttcttgg catttggccc atattctcaa cttggatgaa aatgatgcca
    11101 accgtgtggt cttcaatgaa atcaccaagg atgcagtcaa aaatgctttt aaagaacctc
    11161 gtaagatcga tatggacttg gtcgatgccc aacaagctcg tcggatcttg gatcgcttgg
    11221 tagggtattc gatttcgcct attttgtgga agaaggtcaa gaagggcttg tcagcaggtc
    11281 gcgttcagtc cattgccctt aaactcatca ttgaccgtga aaatgaaatc aatgccttcc
    11341 agccagaaga atactggaca gttgatgctg tctttaaaaa gggaaccaaa caatttcatg
    11401 cttccttcta tggagtagat ggtaaaaaga tgaaactgac cagcaataac gaagtcaagg
    11461 aagtcttgtc tcgtctgacg agtaaagact tttcagtaga tcaggtggat aagaaagagc
    11521 gcaagcgcaa tgctccttta ccctatacca cttcatctat gcagatggat gctgccaata
    11581 aaatcaattt ccgtactcga aaaaccatga tggttgccca acagctctat gaaggaatta
    11641 atatcggttc tggtgttcaa ggtttgatta cctatatgcg taccgattcg actcgtatca
    11701 gtcctgtagc gcaaaatgag gcggcaagct tcattacgga tcgttttggt agcaagtatt
    11761 ctaagcacgg tagcaaggtc aaaaacgcat caggtgctca ggatgcccat gaggctattc
    11821 gtccgtcaag tgtctttaat acaccagaaa gcatcgctaa gtatctggac aaggatcagc
    11881 ttaagctata tacccttatc tggaatcgtt ttgtggctag ccagatgaca gcggccgttt
    11941 ttgataccat ggctgttaaa ttgtctcaaa aaggggttca atttgctgcc aatggtagtc
    12001 aggttaagtt tgatggttat cttgccattt ataatgattc tgacaagaat aagatgttac
    12061 cggacatggt tgttggagat gtggtcaaac aggtcaatag caaaccagag caacatttca
    12121 cccaaccgcc tgcccgttat tctgaagcaa cactgattaa aaccttagag gaaaatgggg
    12181 ttggacgtcc atcaacctat gcgccaacca ttgaaaccat tcagaaacgt tattatgttc
    12241 gcctggcagc caaacgtttt gaaccgacag agttgggaga aattgtcaat aagctcatcg
    12301 ttgaatattt cccagatatc gtaaacgtga ccttcacagc tgaaatggaa ggtaaactgg
    12361 atgatgtcga agttggaaaa gagcagtggc gacgggtcat tgatgccttt tacaaaccat
    12421 tctctaaaga agttgccaag gctgaagaag aaatggaaaa aatccagatt aaggatgaac
    12481 cagctggatt tgactgtgaa gtgtgtggca gtccaatggt cattaaactt ggtcgttttg
    12541 gtaaattcta cgcttgtagc aatttcccag attgccgtca tacccaagca atcgtgaaag
    12601 agattggtgt tgagtgtcca agctgtcatc agggacaaat tattgagcga aaaaccaagc
    12661 gtaatcgcct cttctatggt tgcaatcgct atccagaatg tgaatttacc tcttgggaca
    12721 agcctgttgg tcgtgactgt ccaaaatgtg gcaacttcct catggagaaa aaagtccgtg
    12781 gtggtggcaa gcaggttgtt tgtagcaaag gcgactacga ggaagaaaag attaaataag
    12841 aggaggggcc cgaaagtaaa tttcaggctc cttttggtta gaacttgaca aaatacatca
    12901 ttttatgcga aactagaaga agattatttt aactaggaga agttatgcgt cttatctatc
    12961 tgataattgg ttttttatca ctggccttgg ctattgttgg ggttgtttta cccttgttgc
    13021 ctacaacacc tttccttttg ttgtctattg cttgtttctc cagaagttcc aagcgattcg
    13081 aagactggct ttatcatacc aagctctatc aaacatatgt agctgatttt cgcgagacta
    13141 agtctattac gcgtgaacga aagaaaaaaa tcatcgtatc catttacatt ttgatgggga
    13201 tttctattta ttttgcccct ctcttaccag tcaaaatcgg tctgggtgct ttgaccatct
    13261 ttatcactta ttatctcttc aaggtcattc cagacaaaga atagttaaaa cagtagttat
    13321 ttaccttgat aaaattgaaa gcatattcat aacaatatga tataataaat ttgaagtaat
    13381 attcaaggag aatcaaatga tttacgaatt ttgtgctgaa aatgtgactt tacttgaaaa
    13441 agcgatgcag gctggagctc gtcggattga actctgtgat aatctagcag ttggtgggac
    13501 aacacctagc tatggagtga ctaaggcagc ggttgaactg gcagctaact acgatacaac
    13561 catcatgacc atgattcggc cacgtggtgg tgactttgtc tataatgacc tagaaattgc
    13621 tatcatgcta gaagacattt gtttgactgc tcaggctgga agtcaagggg ttgtatttgg
    13681 agctttaact gctgataaaa agttggataa gcctaatctg gaaaagttaa ttgctgcatc
    13741 aaaaggaatg gaaattgtct ttcacatggc ctttgatgaa ctaagtgatg aagatcaacc
    13801 ggaagctatt gactggctca gtcaagccgg tgtcactcgt atcctaactc gtgctggtgt
    13861 gtctggcgac tccttagaaa aacgttttgt tcactatcac agaattttgg agtacgctaa
    13921 aggtaaaatt gaaattctac caggtggggg gattgacctt gacaaccgtc aaacctttat
    13981 tgaccaggtg ggggtaacac aattgcatgg tactaaggtt gttttttaaa aaatagaaag
    14041 gaactgctag ccttgggtag cagttttcac ttatgtttga aatttttaaa tcctatcaat
    14101 ttaatcaaga aaaggctcat gattatggtt ttatagaaaa tagcgaagtc tggacatata
    14161 gttgccagat tttgcaaggt gactttgtca tgactgtgtc catcactgct gataatgtga
    14221 actttcaagt ctttgaccaa gagactggtg acctctatcc tcacgttcat atggaaagca
    14281 tgaggggaag ttttgtcgga aatgtccgtg aggcttgtct ggagattctt taccagattc
    14341 ggaaggcttg ttttgatgtg caagatttta tctgtcatca gactaagcgt atcatgactc
    14401 aagttcagga aaagtatgga aaccagttgg agtatctgtg ggaaaaatcg cctgatacag
    14461 ctgtattgcg ccatgaaggc aatcaaaagt ggtatgccgt cttgatgaaa atctcttgga
    14521 ataagctgga aaagggcaga gaaggacaag tggaagcagt caacctcaag catgaccaag
    14581 tagctaattt gctttcacaa aaggggattt atccagcctt ccatatgagc aagcgctact
    14641 ggattagtgt gtcccttgat gatactttat cagatgaaga agtactggaa ttgatagaaa
    14701 aaagttggaa cttaacctct aaaaaatgaa atattttaat aattttcatg aactttcaat
    14761 tagctaaata ttctttactg aagaaatttt tagaaaatat aggatttacc acactagagg
    14821 aatatggtgc catcttcaaa tacctgattg agaatgtcaa gacggatcgt cagatcatct
    14881 gttcgcctca ctgtcatgat gacctcggaa tggcagtggc aaatagcctt gctgctgtca
    14941 agaatggtgc aggacgtgtt gaagggacta tcaatggtat tagggagcga gctgaaaatg
    15001 ctgctttgga agaaattgca gtggctctca atattcgcca agattactac caagtagaaa
    15061 ccagtattgt cctaaatgag accatcaata cgtcagaaat ggtttctcgc ttctctggta
    15121 ttccagttcc taaaaacaaa gccgtcgttg gtggcaatac cttctcccac gaatctggta
    15181 ttcaccaaga tggagtcctt aaaaatcctc tcacttatga gatcatcaca cctgaattgg
    15241 ttggtgttaa gattccgctt ggaaaattat ctggtcgcca tgcttttgtt gagaaactga
    15301 gagaattggc cctagatttt acagaagagg atatcaaacc actctttgct aagttcaagg
    15361 cactggccga taagaagtaa gaaatcacag atgcagatcc tcgagctttg gtagctggaa
    15421 ccatggttga aaatccagaa ggcttccact ttgatgattt acaacttcaa actcatgcag
    15481 ataatgacat tgaagcgctc gttagcctag ccaatatgga tggtgagaaa gtcgaattta
    15541 atgcgacagg gcaaggttcc gttgaagcaa tctttaacgc tatcgataag ttctttaacc
    15601 aatctgttcg tttggtgtcc tacactatca atgcggtaac agatggaatc gatgcccagg
    15661 atcgggtttt ggtcactgtt gaaaacagag atacagaaac catctttaat gcagcagggc
    15721 ttgattttga tgtgttgaag gcttctgcta ttgcctatat aaacgctaat acctttgttc
    15781 aaaaagagaa tgcaggtgag atgggacgca gtgtttctta ccacgatatg cctagtgtgt
    15841 aaaggagaag gctatggcaa agaaaatagt agctctagta ggagacggaa ttggcccaga
    15901 aatcatgtag gctggtttag aagttctgga ggctctagct gaaaaaacag gttttgacta
    15961 tgagattgac agacgaccgt tcggaggtgc agatattgat gcagcaggac ctcccttacc
    16021 tgatgaaacc cttaaggcaa gtagggaagc agatgctatc ctactagcag ctatcggtag
    16081 tcctcagtat gatggagcag cggttcgccc tgaacaaggc ctgatggctc tccgtaagga
    16141 actcaatctt tacgctaata ttcgtcctgt aaaaatcttt gacagtctca agtatttgtc
    16201 accactcaaa ccggaacgaa tttctggtgt agactttgtc gtggtgcgtg aattgacagg
    16261 cgagatttac tttggagatc atattcttga agagcgcaaa gcgcgtgata tcaacgacta
    16321 tagctatgag gaagtggagc ggattattcg caaagccttt gaaattgcaa gaaatcgcag
    16381 aaaaatcgtt actagtatcg ataagcaaaa tgttctagcg acctcaaaac tctggcggaa
    16441 agtagctgag gaagtcgcac aggatttccc agatgtaacc ttggaacacc agctggtaga
    16501 ctcagctgct atgcttatga ttaccaatcc tgctaagttt gatgttattg taacggagaa
    16561 tctttttgga gatattttat ctgatgaatc aagcgtctta tctggtacac ttgaggttat
    16621 gccatcagcc agtcattctg aaaatggacc aagtctctat gaacctattc acggttcagc
    16681 acctgatatt gcaggtcaag gaattgccaa tcctacttcc atgattttat cagttgccat
    16741 gatgttgaga gatagtttcg gacgttatga ggatgcagag cgtatcaaac atgctgttga
    16801 gacaagtctg gcggcaggaa ttttaacgag agatatagga ggtcaggctt caacaaagga
    16861 aatgacggaa gctattattg caaggttatg aagttagacg aaaaaattac tctagtcctt
    16921 ttgatttgga atgtcatcat tttcttgatt tatggcattg acaaattcaa ggcaagaaga
    16981 agaacttggc gcatccaaga gaaaatctta ctcattttag cccttacttg tggtggtttt
    17041 ggggcctggt tagctggaat cacttttcac cacaagactc gaaaatggta ctttaaaaca
    17101 gtttggtttc ttgggatggt gaccacacta gtagccttat attttatttg gaggtaatgg
    17161 atggcagggt cttcgaggga acacgctgct tgggttctag cggactatgg ttttaaggtc
    17221 gtgattgcag gatctttcgg tgacattcat tacaataatg aactcaataa tggcctgttg
    17281 ccaatcgttc agcctagaga ggttagagag aaactagccc agctaaaacc aaccgaccag
    17341 gtaactgtgg acttggaaca acaaaaaatc atctcaccag ttgaagaatt caccttcgag
    17401 atagatagcg agtggaaaca taaactccta aatagtttgg atgatatcgg tattaccttg
    17461 cagtatgaag agttgattgc tgcttatgaa aaacaacgac cagcctactg gcaggattag
    17521 aaaaaataga aaaggaaata tagtaaactg aaataagatg taaacaaatg aattagagct
    17581 taacatccat ttccagcaat tttttagaaa ctacagtgga ctattctgga ttcaacacat
    17641 tataaaatta tgacaaaaca cattcacaag aaggctacga cattttaaaa ggtgagggcg
    17701 gatgtatcgt ttgccctact aaagttggtt acattatcat gaccagcaac aaggcaggac
    17761 ttgagcgtaa gttcgcagcc aaagaacgta agcgtaacaa accaggtgtt gttctctgcg
    17821 gtagcatgga tgaacttcgc gctttagcgc aactcaaccc agaaattgaa gcattctact
    17881 aaaaacattg gatgaagata ttcttcttgg ttgtatcctt ccttggaaac cagaagcctt
    17941 tgaaaaactc aaagcatacg ggaatggccg tgaagaactt atgactgatg tacgtggtac
    18001 tagctgtttt gttatcaagt ttggaaaagc aggtgaacaa ttggctgcca agctttggga
    18061 agaaggtaaa atggtctacg cctcatatgc ttcaatgaca aaacgattga aactcgctat
    18121 gagagcaagg tgtaatggtg tctatggtcg ataaggacgg caaactcatc ccagaacaag
    18181 gaggagcacg ttcaacttca ccagcaccag ttgtgatccg taaagggctt gacattgata
    18241 aaatcatgat gcacctgtca gatactttta actcatggga ctaccgtcag gttgagtatt
    18301 attaagataa aaaaagaagt ctagtgttat gagatattaa agctcctaac actggacttt
    18361 ttgtttagaa tttcttttct ttttctatag gatatggtat tctatgtaga aaatatatgt
    18421 taataagtaa tgccaatatt taaacatcat tagtaaaagg agttagattg atgaataaaa
    18481 gaaaagttag tttagaagat ttttataaat ggtatagtct aaataaagaa gagttattaa
    18541 ataaggcaac tgttggtgaa aagtttaatg ataaattaaa agaagagttt ctccaggaat
    18601 ggcctttgga taggatttta acaatgtcaa tcgatgaata tgtaatagga aagggacagc
    18661 aaaataagtc tttatgctac gctcttgaga agggaaaata caaaaatcta tttcttggaa
    18721 tttctggtgg ctcagcttca aaatttggta tttattggaa taaaaaaaca aacaaatata
    18781 aagatcaagc taataatgag atttcagagt tggatcagcg attttcaaaa ttaaaatcag
    18841 atttgtatga aattatcaaa gaaggtattc gttttaactt tgaaaatcct atttttgata
    18901 tgaaaagatc aacaaatgaa tttattggtc gttctgctat ggtgacaaaa ttactttgta
    18961 tctatactga gggagatcct ttctttggtg taaatattaa tagtcagaaa gaattttgga
    19021 accactttgt ttctcagaca aatcaaggtg gaccttatct gcaaaatcat aaaataattg
    19081 aactagtgtc caaaacttat cctgagttgg agccatcgaa attaggaact atgctttttg
    19141 agtattctaa gctttttatg gaaaataagg aagacaatag tacaatggat tcatcaaaca
    19201 attttcgtca tcaattaact caatctctat taaagtctcc aaacctcatc ctccgtggtg
    19261 ctcctggcac aggaaagact tatcttgcta aagaaattgc caaagaatta acggatggca
    19321 acgaagacca aatcggattt gtacaatttc acccatccta tgattatacg gattttgtag
    19381 aaggtttaag accagtatca aatggggatg gagctattga gtttaggcta caggacggta
    19441 tttttaaaga tttttgtcag aaagcaaaag aaacccaatt gattggagga caagataatt
    19501 ttgatgaggc ttgggattct tacttagaat atataaatgt tgctgaagaa aaagaatata
    19561 taacaaaaac atcttactta tctattaata gtagacaaaa tttgtcagta aattatgata
    19621 gtggtgtttc aggatggtca ctacctagca aatatgttta cgagttgtat aaagataaaa
    19681 attataataa gcaagaatac tacaaaagtg gtggaaaaac tgtcctagaa acattgagaa
    19741 agagatttgg tttgaaagac tatgtttccc caacagaaat tgatactgat aagaaattcg
    19801 tcttcatcat cgatgaaatc aatcgtgggg agatttctaa gatttttggc gaactctttt
    19861 tctctatcga ccctggctat cgtggtgaaa aaggaagtgt ttctacccaa tatgcaaatc
    19921 tacacgaaac tgatgaaaag ttctatatcc ccgaaaatgt ttacatcatc ggaactatga
    19981 atgatattga tcgttcagtg gatacctttg attttgctat gcgtcgtcgt tttcgttttg
    20041 ttgaagttac tgccgagggt caagttggca tgttggataa agagctgaat atccatgcag
    20101 aagaagcaaa aattcgtcta agaaacttga acgctgctat cgaaaatgtt caggaattaa
    20161 acagtcatta tcatattgga ccaagttatt ttcttaagtt gaaggatgta gattttgact
    20221 atgaattact ctggtctgat tatattaagc ctctcctaga agactacttg cgaggttctt
    20281 atgatgaggt tgaaactttg gaaactttga aaaaagcatt tgaactgaca aataatgagc
    20341 aaaaagatca ggcagtagct gatgacaatg aaggtgatga aaacgatgat gcggattact
    20401 gataatcaac acaagattat taaagaaaaa tttgttgaag aatatcctaa actaagcaat
    20461 cttcttttag acagaacctt ggaaagtcta tcccaagatg aacgtatttt catttttcca
    20521 aatgatttga ctcatactcc tgatttggat aaggaccaaa agatttttga aacagtcaat
    20581 cagaaaatca agacagggaa cgtgattggt tttcttggat atggtcagga aagattaacg
    20641 atttcctcac gattttctga tgagagtaat gaccattttt tgcattatct cttaaacaag
    20701 gttctttata tcaatctcac tagtttagat gttgctttgt ctcgtgaaga gaggctttat
    20761 caacttttga tgtatctctt ccccaagtat ctacaagctg ctattcgaaa aggtctttat
    20821 aaggaatatc atcgattttt tcataacgac agtaatgtta agggagtgat tgatgtaaga
    20881 agccatctca agaaaaatct tcctttcacg ggaaatattg cctacgcaac gagagagttc
    20941 acctatgata atcccctcat gcagttggtc cgtcacacta ttgaatacat taagaatcag
    21001 aaaagcattg gtcaaggggt actagataat ctctcaacta gtcgtgaaaa cgtatctgaa
    21061 atcgtgcgtg taacgccctc ttataaacta gctgatcgtg ctaagattac tcggagaaat
    21121 caatctaaac ctatacgtca tgcatacttt cacgagtaca gaaacttaca agaactttgt
    21181 ctgatgatcc taaaccaaga aaagcacggt ttagggtatc aagatcaaaa aatctatggt
    21241 attctctttg atgttgcctg gctttgggaa gagtatgttt acaccttgtt gccaaaaggt
    21301 tttgtacatc ccagaaataa ggataagacg gatggaattt cagtattttc tgttgggaaa
    21361 cgaaaagtat atccagattt ttatgacaga gaacgaaaga ttgttctaga tgcaaaatat
    21421 aaaaaactgg aattgactga aaaaggaatc aaccgtgagg acttattcca gctgatttcc
    21481 tattcttata ttttaaaagc tgagaaggct ggactgattt ttcctagtat ggagcagtca
    21541 gtaaatagtg aaataggaaa agtagctggc tatggagctc aattgaagaa gtggtctatt
    21601 cgaatccctc agaatgcctc atcctatagt gcattttgta aaatgatgga aaattcagaa
    21661 gaaaatttta aagcgattat tgatgaagaa gtggggagaa aataatttcc cctctttctt
    21721 ttatttttaa cacaagtaaa acccgaacga tatattttaa ttcataaaaa aaattgacaa
    21781 aaactgtact ttggtttata ataaattaag gaaacgtcgg aaaaggcgta gtgatgcgag
    21841 agcataggta ggtcattaca aaagaaacga gacatcgata tgttaaatga atttccaatt
    21901 tttgattacg aagatattca attgattcca aataaatgtg tcattaaaag ccgtgcagaa
    21961 gcggatacaa gtgtcacttt aggaaatcac acctttaaac tacctgttgt gccagcgaat
    22021 atgcagacga ttttggatga aaatgtagca gagcaactgg ctaaaggtgg ttacttctac
    22081 attatgcacc gttttgatga ggcaggacgc attcctttta ttaaacgaat gcacaatcaa
    22141 gggctcattg cttccatatc tgtcggtgtt aaggactatg agtatgattt cgttagacag
    22201 ctcaagactg atgctcctga gtatatcact attgatattg ctcatggtca tgcggatagc
    22261 gtgatttcta tgattcaaca catcaagaaa gaattgccag atacctttgt cattgctgga
    22321 aatgtgggaa caccagaagc tgtgcgtgaa ttggaaaatg ctggtgcgga tgctactaag
    22381 gtcggaatcg gtcctggtaa ggtttgtatc accaaggtta agactggttt tggtacaggt
    22441 ggttggcagt tggctgctct acgctggtgt gtcaaggctg cgcgtaaacc gattatcgct
    22501 gatggaggaa ttcgtactca cggtgatatt gccaagtcta tccgcttcgg tgctagcatg
    22561 atcatgattg gttccctctt tgcaggacat attgaaagtc cagggaaaac gattgaagtc
    22621 gatggtgaac agttcaaaga atattatggt tcagcctcac aatatcaaaa aggtgcttac
    22681 aaaaatgtgg aaggcaaacg tatcttgctt cctgctaaag gtcatctgca agacacttta
    22741 actgagatgg aacaagacct tcaaagtgct atttcttatg caggtggacg tcaggttgct
    22801 gaccttaaac acgttgatta tgtgatcgtg aaaaactcca tctggaatgg ggatgcttcc
    22861 cactaagacg gggtctttga ctaaaaaact tgttattaga gcaaatttct gttataataa
    22921 aacaagtttc cacccttagt gtaatggata tcacgtaaga ttccggttct tgagatgggg
    22981 gttcgattcc ctcagggtgg atgtaaacat tctaaaaagc ctttaatagg gcttttttct
    23041 ttacactgct ctaaatttac cgctaaaact gagaatctct gtctaaagaa tttccaaatg
    23101 ctttccagtc ccgttttaga gtgactcagg gggctttttt tgatataata aaaaggactg
    23161 ttatcagtta gaaagaggtt ggtatgaaag aattacaaac tgtactaaag aaccattttg
    23221 caatcgaatt tacagacaaa aagttactgg aaactgcctt tactcatacg agttatgcca
    23281 atgagcaccg cctcttaaaa atttcacata atgaacgctt ggaattttta ggagacgctg
    23341 ttctacagtt attgatttca gaatatctgt ataaaaaata tcctaaaaag cctgaaggtg
    23401 acctatcaaa actccgtgct atgattgtcc gtgaggagag tttagctggt tttgcgcgtg
    23461 attgccagtt tgaccagttt atcaagttgg gtaaagggga agaaaaatct ggtggtcgca
    23521 atcgtgacac cattcttggt gatgcctttg aagcctttct tggtgccctt cttttggata
    23581 aggatgtggc caaggtcaag gaatttatct atcaagtcat gattcctaag gttgaagcag
    23641 gcgaatttga gatgattaca gactataaaa cccatctcca agagttactt caggtcaatg
    23701 gtgatgtggc tattcgttat caggtgattt ctgaaacagg gcctgctcac gataaggtct
    23761 ttgatgtaga agttcttgtt gaaggtaaga gtatcggtca aggccaaggt cgttctaaga
    23821 aattagcaga gcaggaagct gccaaaaatg ccgttgagaa ggggctggat tcatgtattt
    23881 aaaggaaatc gaaattcagg ggttcaagtc ttttgctgat aagaccaagg tcgtttttga
    23941 ccaaggtgtg acggcagttg ttggaccaaa tggatctgga aagtccaata ttacagaaag
    24001 tctgcgttgg gctttggggg agtctagtgt caagagtctc cgtgggggca agatgccgga
    24061 tgtcatcttt gctggaacag aaagtcgcaa accgctcaat tatgcttctg tagttgtgac
    24121 tctggataat catgacggat ttatcaagga tgcaggtcaa gaaatcaggg tggaacgcca
    24181 tatctatcgt agtggagata gcgaatacaa gattgacggc aagaaagtcc gtctgcgtga
    24241 tattcatgac ctcttcttgg atactggatt gggacgagat tccttctcta ttatttccca
    24301 agggaaggtt gaggagattt ttaattccaa gcctgaggaa cgacgagcta tttttgaaga
    24361 agctgctgga gttttaaaat acaagactcg cagaaaagaa accgagagta aactgcagca
    24421 aactcaggat aatctggacc gcttagagga cattatctac gagttggata atcaaatcaa
    24481 gcctcttgag aagcaagctg agaatgcccg taagttttta gacttggaag gacaacgtaa
    24541 ggctatttat ttagacgttc tggttgctca aatcaaggaa aataaggctg aactagagtc
    24601 gacagaagaa gagttggctc aggttcaaga actcttgatg agttattacc aaaagcgtga
    24661 aaaattagaa gaagaaaatc aaactcttaa aaagcaacgc caagatttac aggctgaaat
    24721 ggccaaagac caaggcagtt tgatggattt gaccagtctg attagtgact tagagagaaa
    24781 attagcccta tcgaaactgg aatctgagca agtagccctc aatcaacagg aagcacaagc
    24841 ccgtttggct actttggagg ataagagaag ttcactcagc caagaaaaat ctgataaaga
    24901 aagctcttta gccctcttgg aagaaaatct agtccaaaat aatcaaaaac tcaatcgatt
    24961 agaggctgaa ttgctagctt tttcagatga tcctgatcag atgattgagc tcttacgtga
    25021 acgctttgtg gcccttttac aagaagaagc agatgtctca aaccaactga cccgtattga
    25081 gaatgagttg gaaaatagtc atcagctttc tcaaaaacaa gcagatcaac tagaaaagct
    25141 gaaagaacag ttggctacag ctaaagagaa ggctggtcag caaaaggctg agcttgaaac
    25201 tgccaaggag caggttcaga aattattggc cgactatcaa gtctgtgcta aggagcaaga
    25261 ggagcagaaa acttcctatc aagctcaaca aagtcaactc tttgaccgtc tggatagtct
    25321 caaaaacaag caggctagag cgcaaagttt ggaaaatatc ctgagaaatc atagtaactt
    25381 ttatgcaggt gttaagagtg ttctccaaga gaaagatcgt ctaggtggga ttattggagc
    25441 agttagtgag cacctgacct ttgatatgca ttatcaaact gccctagaaa ttgcgcttgg
    25501 agcgagtagt cagcacatta ttgtagaaga tgagaatgcg gcaaccaaag ccattgattt
    25561 actcaaacga aacagatctg gtcgtgcaac cttccttcct ttgaccacta tcaaggctcg
    25621 tacgatttct agtcagaacc aagatactat tgctgcaagt ccaggatttc tgggcatggc
    25681 agatgagctg gttactttcg atactagact ggaagccatt ttcaagaatt tgctagctac
    25741 aacggccatt tttgataccg tggagcatgc gcgtgcagca gcgcgccagg ttcgttatca
    25801 ggttcgtatg gtgacattgg acggaacaga gctgcgcaca ggtggttctt atgcaggtgg
    25861 agctaatcgc cagaataaca gtattttcat caagccagaa ctggagcaat tacaaaaaga
    25921 aattgctgaa gaagaagcaa gtttgcgttc agatgaagtg agtttgaaga acttgcaaga
    25981 tgagctagct agattgacag aaagattaga agccatcaaa tctcagggag agcaggctcg
    26041 tattcaggag caaggcttgt ccctcgccta tcagcagacc agtcagcaag ttgaagagct
    26101 agaaactctt tggaaactcc aagaagagga attaaatcgt ctttctgagg gagaatggca
    26161 agcggataag gaaaaatgcc aagagcgcct tactacaatc actagtgaaa agaataatct
    26221 ggaagctgag attgaagaga ttaagtctaa taaaaacgcc atccaagaac gttatcaaaa
    26281 cttgcaggaa gagctagctc aagctcgtct acttaagaca gaactgcaag ggcaaaaacg
    26341 ttatgaagtt gctgatattg aacgcttagg taaggaacta gataatcttg atattgagca
    26401 agaagaaatt cagcgccttc ttcaagaaaa ggttgacaat cttgagaaag ttgatacgga
    26461 tttgctcagt caacaggctg atgaagccaa aactcaaaaa acaaatctcc aacaaggttt
    26521 gattcgcaag cagtttgagt tggatgatat tgagggtcaa ctggatgata ttgctagtca
    26581 tttggatcag gctcgccagc agaatgaaga gtggattcgc aagcaaactc gtgctgaagc
    26641 caagaaagaa aaggttagcg agcgcttgcg ccatctacaa aatcaattaa cagaccagta
    26701 ccagattagc tatactgaag cactagaaaa agcgcatgag ttggaaaatc tcaatctggc
    26761 agagcaagag gtgcaggatt tagagaaggc tattcgctca ctgggacctg tcaatttaga
    26821 cgctattgaa cagtacgaag aagttcacaa ccgtctggat ttcctaaata gccaacgtga
    26881 tgatattttg tctgcgaaaa acctgcttct tgaaaccatc acagagatga atgatgaggt
    26941 caaggaacgc tttaaatcaa cctttgaggc cattcgtgag tcctttaaag tgaccttcaa
    27001 gcagatgttt ggtggaggtc aggcagactt gatattgact gagggcgacc ttttaacagc
    27061 tggtgtggag atttctgttc aacctccagg taagaaaatc cagtcgctta acctcatgag
    27121 tggtggtgaa aaagctctat cggctcttgc cttgcttttc tccattattc gtgtcaagac
    27181 cattcctttt gtcatcttgg atgaggtaga ggctgcgcta gacgaagcca atgttaaacg
    27241 tttcggggat tatctcaacc gctttgataa ggacagtcaa tttattgtcg taacccaccg
    27301 taaggggacc atggcagcgg ccgattctat ctatggagtg accatgcaag aatcgggtgt
    27361 ttcaaagatt gtttcagtta agttaaaaga tttagaaagt attgaaggat gacaattaaa
    27421 ctagtagcaa cggatatgga cggaaccttc ctagatggga atggacgctt tgatatggat
    27481 cgtctcaagt ctctcttggc ttcctacaag gaaaaaggga tttactttgc ggtggcttcg
    27541 ggtcggggat ttctgtctct ggaaaaatta tttgctggtg ttcgtgatga cattattttc
    27601 atcgcggaaa atggcagttt ggtagagtat caaggtcagg acttgtatga agcgactatg
    27661 tctcgtgact tttatctggc aacttttgaa aagctgaaaa cgtcacctta tgtagatatc
    27721 aataaactgc tcttgacggg taagaagggt tcatatgttc tagatacggt tgatgagacc
    27781 tatttgaaag tgagtcagca ttataatgaa aatatccaaa aagtagcgag tttggaagat
    27841 atcacagatg acattttcaa atttacaacc aacttcacag aagaaacgct ggaagctggt
    27901 gaagcttggg tcaatgataa tgtccctggt gtcaaggcta tgacaactgg ctttgaatct
    27961 attgatattg ttctggacta tgtcgataag ggtgtagcta ttgttgaatt agctaaaaaa
    28021 cttggtatca caatggatca ggtcatggct tttggagaca atcttaatga cttacatatg
    28081 atgcaggttg tgggacatcc tgtagctcct gaaaatgcac gacctgaaat tttagaatta
    28141 gcaaagactg tgattggtca ccataaggaa cggtcggtta tagcttatat ggagggctta
    28201 taatggcaga tataaaattg attgcattgg acttggacgg gaccttgctg actactgata
    28261 aaaggctgac ggatcgtacc aaggaaacct tgaaagctgc gcgtgatcgt ggtatcaagg
    28321 tcgtattgac aactggtcgt cccttaaaag ccatggattt ctttctccat gagttaggga
    28381 ctgacggtca ggaagatgag tataccatta cttttaatgg tggattagtt cagaaaaata
    28441 caggagaaat ccttgataaa acagtctttt catatgatga tgtggcacgt ttgtatgaag
    28501 aaacagagaa attatcactg cctctcgatg ccatctcaga aggaacagtt tatcaaatcc
    28561 aatcggacca agaaagtctt tatgccaaat tcaatccagc tttgaccttt gttccagtgg
    28621 actttgaaga cttatctagt caaatgacct acaacaaatg cgtgactgcc tttgctcaag
    28681 aacccttgga tgcagccatt cagaagattt ctccagaatt gtttgaccaa tatgaaatct
    28741 ttaaatcacg tgaaatgttg ctagaatggt caccaaagaa tgttcataaa gcaacaggtt
    28801 tggcaaaact aatcagccat cttggaatcg accaaagtca agtgatggct tgtggtgacg
    28861 aggccaatga cctctctatg attgaatggg caggtcttgg tgttgctatg caaaacgctg
    28921 ttcctgaagt aaaggcagcc gcaaatgtag tgacgccgat gaccaacgat gaggaagctg
    28981 tcgcctgggc tatcgaagaa tatgtgctaa aggagaacta agatatggga ttgtttgacc
    29041 gtctattcgg aaaaaaagaa gaacctaaaa tcgaagaagt tgtaaaagaa gctctggaaa
    29101 atcttgattt gtctgaagat gttgatccta ccttcacaga agttgaggaa gtttctcagg
    29161 aagaagcaga ggttgaaatt gttgaacaag ctgtgttcca agaagaggaa atccaagaca
    29221 cagttgaaga aagtctggat ttagagccag ttatagaagt ttctcaaaaa gaagtcaaag
    29281 aatttccaca ctcagaagaa gggaatactg agtttctaga gactgtagaa gaaaataatt
    29341 ctgaaattct tgaagcagaa aggcctcaaa cagaagaaac tgttcaggaa aaatatgacc
    29401 gcagtcttaa gaaaactcgc acaggtttcg gtgcccgctt gaatgccttc tttgctaact
    29461 tccgctctgt tgacgaagaa tttttcgagg aactggaaga actgttgatt atgagtgatg
    29521 ttggtgtcca agtcgcttct aacttaacgg aggaactacg ttacgaagcc aagcttgaaa
    29581 atgccaagaa acctgatgca cttcgtcgtg tcatcattga gaaattggtt gagctttatg
    29641 aaaaggatgg tagctacgat gaaagcatcc acttccaaga taacttgaca gttatgctct
    29701 ttgttggtgt gaatggtgtt gggaaaacaa cttctatcgg aaaactagct caccgctaca
    29761 aacgagctgg taagaaggtc atgctggttg cagcagatac cttccgtgcg ggtgcagtag
    29821 ctcagctagc tgaatggggc cgacgagtag atgttccagt agtaactgga cctgaaaaag
    29881 ctgatccagc cagcgtggtc tttgatggta tggaacgtgc cgtggctgaa ggtatcgata
    29941 ttctcatgat tgatactgct ggtcgtctgc aaaataagga taaccttatg gctgagttgg
    30001 aaaagattgg tcgtattatc aaacgtgttg tgccagaagc accacatgaa accttcttgg
    30061 cacttgatgc atcaacaggt caaaatgccc tagtacaggc caaagaattt tcgaaaatca
    30121 cacctttaac gggaattgtt ttgactaaga ttgatggaac tgctcgagga ggtgtggttc
    30181 tagccattcg tgaagaactc aatattcctg taaaattgat tggttttggt gaaaaaatcg
    30241 atgatattgg agagtttaac tcagaaaact tcatgaaagg tctcttggaa ggtttaatct
    30301 aatcagaagc aaaaatcctg caaggcataa acttgcagga aattttttta ttctaagcga
    30361 ccatcttgac gataggcgat atctggttgc caagtccatt tggcaccgaa tttttcaagt
    30421 aggtcaaagc tggcttgagg tcccatgctt ccagctttat agtcatgaag tggggcacca
    30481 ttttcatccc agagctcttc aatacggtca atcaacttcc atgatgcacc aacttcatcc
    30541 cagtggctaa agttagttga gttgttattt aggacatcat aaatcaattt ctcgtatggt
    30601 tctggagaag caccagttgc agtcgcatct gtacggtaat caagtgagtt aggagccaag
    30661 ttaaattctt ctcctacttg cttcccattt aggctaagag agaagccttc tgttggttga
    30721 atatagatgg tcaaaatatt tggagcaagt ggttctccaa agatagaatc catttgttta
    30781 aagacgatgt tgacatgagt tcctttttca gtcagtcgtt tacctgtacg gaaaaagaaa
    30841 ggaacactac ggaatcgatc gctgtctaca aagaaggcac cagatgtaaa ggtttcagtt
    30901 gttgattctg gattcacatt tggctcgcta cgataagaga tgtatttcat gccatcaatc
    30961 ttaccagagc ggtattgccc acggataaag tgttctttga gttcttcatc agttggatga
    31021 tagaggtttt taaagacctt aatcttttca gcacgaatct cgtcttttgt gaagcttgct
    31081 ggtttgtcca tggcgaggag cgaaagaagt tgtagagtgt ggttttggac catgtcacgg
    31141 agggcaccgg attggtcata gtagccacca cgttcttcta cacccaagcg ctccgcaaag
    31201 gtaatttgaa cattgtcgat aaaatccttg ttccaaacgt tttcaaaaat caagtttgca
    31261 aagcgaactg caaagatgct ttggatcatt tccttaccaa gataatggtc gatacggaaa
    31321 atttgttctt cgtcaaatgt tgctaggagt tcgtcattca acttgcttgc agttgcgtaa
    31381 tctgtaccaa atggtttttc aacgatcaag cgctcaaaac ctttgccatc gacaatgttt
    31441 tcagatttga ggtgtttggc aatggttcca aagaactgag gtgccataga caagaagaag
    31501 agcttattgt gttcagcttg gtatttttca ttaagctcag cttgtaattg acgcaaagca
    31561 atataatgtt ccgaatcatt gacatcatgg ctttgatagt agaagtggct agcaaattct
    31621 tgggcttgct cggtactatc tgccaaatca aggatggact cgacaactac agattcaaaa
    31681 tattccttac tccaaggtct acgggcagtt ccaataacgg caaagtgctt ggaaagattg
    31741 ccggatttat atagtctaaa aagggaaggg tagagcttgc gtttagccag gtctccactc
    31801 gcaccgaaaa ttgtaacaat aaccttagat gacatctagc tacctaattt ctatttttat
    31861 tcctagtctt gctaggtatg aggaaacctc atttcataaa cttaattcta acataatttt
    31921 ccgaaaaatc aaaaattcca atacgaagta gaaaaactgc aaggaaatcc ttacagtttg
    31981 agtttagacg tttaagacct tatctaagaa ctctttcaga cgagggtgtt gtgggttatc
    32041 aaagatttgg tcaggtgttc cgtcttcaag gaactcgcca tctgcagtaa agataacgcg
    32101 gttggcaacc tgacgagcaa atcccatctc atgggttacg ataatcatgg tcataccttg
    32161 ctcagccaat tccttcataa cgttaagtac gtctccaacc atctcagggt caagggcaga
    32221 agttggttca tcgaagagca tgatgtctgg attcattgct aggccacgag cgatggccac
    32281 acgttgtttt tgaccacctg ataggctatc tggattggca ttagctttat ctgctagtcc
    32341 aaccttttca agcaactcca ttcccaattc ctcagcttct tccttagtca tcaacttgtg
    32401 ctcaatagga gcaaaggtga tgttgtccaa tacagacata tgagggaaga ggttgaagtg
    32461 ttggaatacc atgccgatat tttcacggac gtggtcaaca ttggttgttt tttcagttaa
    32521 atcatagccg ttcacagtga tgtgaccgct agtgacttct tctaaaagat tgaggctacg
    32581 gaggaaagtt gacttaccag aacctgaagg accgatgata caaacaacat ctccttcata
    32641 gaacttagtc gtaattcctt ttaggacttc attttttcca tagtgcttgt gtaaatcatt
    32701 tacatcaatt tttaattttg ccattaacga atcctctttt ctaagcgttt cgctagtcta
    32761 gtcaaaagtg tgataattac aagatagaag atagcaagga ttgcatacat cttgaaactt
    32821 tggtagttac gagcaatgat aatcttacca gtttggaaga gttcaaccaa accgatagca
    32881 gatacgatag ttgtatcttt aagagcgata acgaattggt tgacaaagtt tggcaacatc
    32941 aatttagttg cttgtggcaa gataatctta cgcatggttt ttccataaga gatacccaag
    33001 cttcggctgg cttccatttg gccaactgga acggcctgaa taccaccacg aacgatttca
    33061 gcgatataag cagccgcatt gagtgagagg gcaatggttc cagctacaaa gtcgttaatt
    33121 gggctttgtt ggcctgtgat agactcgatg aagtttggaa ttccccagaa gatgaaggct
    33181 gcaagaatca tcaatggaat accacgaata acgtcaacga aaatctcaga gatgacgcga
    33241 agagatttgt atgggctaac gctaaacata ccgaagataa ttccgatgac aatggcaata
    33301 gcaaatgaga taagagctag agcaagagtg ataccaagac cgctaaggag ttgtttgtag
    33361 ttgttttgaa gcaagcccca gagcgttgtt tcgtcaacag tacttgttga agcagttgaa
    33421 gattcgctag ctaggtattt gtcaagaatc ttttggaatt caccgtttgc tttaaggttt
    33481 gcaagtccgt tgttgaacat ttcaatcagt tctggatttg ctcctttttt aacggcaaag
    33541 gctgtttcac cgattggagt tccagagatt ggagttttca atttttgacc ttggctgata
    33601 gaatatttga gaacaggttc atcatccata acggcatcaa tggcaccagt gtttaaactg
    33661 tcatacattg aagaaccatc agcaaaggtt ttgattttgt aaccgtattt gctttgattt
    33721 tctgttagga aggtttgaga agcagttccg tttttaacac cgactgtctt tccttttaga
    33781 tcttcataag aagcaatatt gcttgattct ttgacaccaa gaatggtatt agcagtgtag
    33841 tatgattctg agaagtcaaa agttgcctta cgagcatctg tgacagacat cccagcaatg
    33901 ataccatcgg cttgaccagc ttggacagca ctgatagcag catcaaaacc agggttggtg
    33961 atttcaattt caaaaccttg gtctttagcg attgccttaa tcaattccat atcaatacca
    34021 gtgtattggt tgcttgaatt ttggaaaaca aaaggtgcaa aagaagaatc gctggcaatg
    34081 atatatttag ccttaacagg aatagctttt aatcctgcga gagtagttgt agttggcact
    34141 gctgaagatg atgaagcagt ccatttcttg ataattttat caagactacc atcttttttc
    34201 atttcagcca aggcttggtt aaattcagta accaggtgct cgtatttact tccttttttc
    34261 acaccgaaag caaaacttcc tacagcttca ccatccattt caatatggag atcttgacct
    34321 tggttaatgg catattcgat aacaggtttg tcatccatca tggcatcgat ggcaccagca
    34381 ctcaagctgt tgttcattaa atcaccagtg tcaaatgttt taatagtaaa gccgtattta
    34441 tctttgattg tttcaaggaa acgttgagcg gcagttccgt ttttaacacc aacggttttg
    34501 ccagttaatt ggtcgtactt gctaattttg tgtgactttg tagtagcaat gacaactttt
    34561 gtatcatagt aagtatcaga catggtgaag actttttcac gttctttagt ctttgtcatc
    34621 cctgccatga tagcgtcggc ttgcccagct tgaaccgcat tgactgctgc gtcaaatcca
    34681 ggataggaca tctgaatgtt ccagccttta atctcagcga ctttgttaat aatgtcaaca
    34741 tcaattcctt tataagtttg atctgaatct ttaaactcaa aaggtgcata ggcggtatca
    34801 gaaacaatct taatcgtttc tgctttggca atacctaatg agaaaattgg gaataaaatt
    34861 agcaaaaatg ctagaaattt tttcttcatt tttagtctcc ttttccgaat attctctcat
    34921 tatatcagaa aaagtaaaaa aaggcaaatt gttatatttt tcgtgtcaga aaatataaca
    34981 ttgatttttc cttttctttc ttgaattgct attaaaaagt gctataataa tagtatatat
    35041 agaagaaaag aggacgggga tatgaagaac aaaagaatat ttaaagactt ccaagcttca
    35101 aaaatgagtt taaacattta cacaagcccc ttgttagcct ttgtttttgt cttcatagga
    35161 gagtttgtgg cttttacttt gtatggtatt ggcttgttag ctctcatcgg acttgctaga
    35221 aattttggag aggctggtca aaatcttgca agctacttgc agaccttgca acagagcttg
    35281 acggataaaa caagtgactt tcgtttaatt ttaggattac tggcctttgg ttttattctt
    35341 aacactgtgt tcagatggac aagaaaagtt gagaaaagac ctattcgaac cttgggattt
    35401 tatagagaga atttcctcag caatcttctg aaaggattta gtctaggctt ggcacttttt
    35461 cttctgacct tgttaggttt agtggtctta ggtcaatatc gtttggaatc cattcacttg
    35521 aatccttatt ctcttgcctt tgtcgtcttt actatcccat tttggatttt acaggggaca
    35581 gcagaagaag tggtggcccg tgcttggcta cttcctcaat tggcctcaag aaccaatcta
    35641 aaactagcta ttcttatatc tagcctgttc tttaccctgc ttcatatggg caattctagc
    35701 ctcacccctc tatctctagt aaatctcttt ttattcggag ttgccatggc tctttatctt
    35761 ctcaaaactg atacagtttg gggtgttgca ggtattcatg gtgcttggaa ttttgctcag
    35821 ggtaatctct ttgggatttt agttagtggt caaccgtcag gaacgtctct gatgaccttt
    35881 ttaccacaag gcaatcaaga ttggctatca ggtggttctt ttggcataga aggttccatt
    35941 atgacaagtc tggtattact actgctgatt gtctatcttg ctaataaatt aaagaaagaa
    36001 aatgaaagga tgtgacttcg gtccgtcctt ttcttcgtga aaatactata agtatgctaa
    36061 aataggaata gcacatggag agaggattct tatgatcaat cacattacag ataatcaatt
    36121 taaactagta tcaaaatatc aaccatcagg agatcaaccc caagctatcg agcagttggt
    36181 ggataacatt gaggggggag aaaaagctca gattctgatg ggggcgactg gaacagggaa
    36241 gacctatact atgagtcagg tcatttctaa agtcaataaa ccaactctgg ttattgccca
    36301 caataaaact ctggctggtc agctctatgg ggagtttaag gaatttttcc ctgaaaatgc
    36361 agttgagtat ttcgtatcct actatgatta ttaccagcca gaggcctatg tcccttctag
    36421 cgatacctat attgagaagg atagttctgt caatgacgag attgacaagc ttcgccactc
    36481 agctacctca gcccttttgg agcgtaatga tgttattgtc gtggcctcag tctcttgtat
    36541 ctatggtttg ggttcgccca aggaatacgc tgatagtgtc gttagtctcc gtcctggtct
    36601 agagatttct cgtgataaac tcttgaatga cttggtcgat attcagtttg aacgtaatga
    36661 tattgatttc caacgcggaa gatttcgtgt tcgtggggat gtggtagaga ttttcccagc
    36721 ttcccgagat gaacatgcct ttcgagtaga attttttgga gacgaaattg accgtattcg
    36781 tgaagttgag gctctgacag gtcaggtgtt gggagaagtg gatcatttag cgattttccc
    36841 agcgacacac tttgtgacca atgacgacca catggaagtt gccattgcaa agattcaggc
    36901 cgagttggag gagcagttag ctgtctttga aaaggaaggt aaactgcttg aagcccagcg
    36961 tttgaaacag cggacagagt atgatatcga aatgttgcgt gagatgggct ataccaatgg
    37021 ggttgaaaat tattctcgcc acatggatgg acggagcgaa ggagagcctc cttatacgct
    37081 tctcgacttc ttcccagatg atttcttgat tatgattgac gagagtcata tgaccatagg
    37141 gcaaatcaag ggcatgtaca atggagaccg ttcgcgtaaa gaaatgctgg ttaattatgg
    37201 tttccgtttg ccgtctgctt tggacaatcg tcctctccgt cgggaggagt ttgagagtca
    37261 cgttcatcag attgtttacg tttcagcgac acctggtgac tatgaaaatg aacagaccga
    37321 gacagtgatt gagcaaatca ttcgtccaac gggactcttg gatccagagg tggaagtccg
    37381 tccgactatg ggacagattg atgacctctt gggtgaaatc aatgcccgcg ttgaaaaaaa
    37441 tgagcgtacc tttatcacaa ctttgaccaa gaaaatggca gaggacttga ccgactactt
    37501 caaggaaatg ggtatcaagg tcaagtacat gcactcggat atcaagacct tggaacggac
    37561 ggagattatc cgtgacctgc gcttgggtgt ctttgatgtc ttggtcggaa ttaacctgct
    37621 ccgtgaagga attgacgttc ctgaagtgag cctcgtagct attctcgatg ctgacaagga
    37681 aggtttcctt cgcaacgaac gtggactcat ccagactatt ggacgtgctg ctcgtaacag
    37741 tgaaggccat gtcatcatgt atgcagacac ggttacccag tctatgcaac gtgctatcga
    37801 tgaaactgcc cgccgtcgga aaattcagat ggcctataat gaagagcatg gtatcgtacc
    37861 acagacaatc aagaaagaaa tccgtgacct gattgccgtg accaaggcag ttgctaagga
    37921 agaggacaag gaagtcgaca tcaatagcct caacaaacaa gagcgtaaag aactcgtcaa
    37981 gaaactagaa aaacaaatgc aagaagccgt cgaagtgctt gactttgaac tggcggctca
    38041 gatccgtgat atgatgttgg aagtcaaggc cttggattag gggaatagta tgatttattt
    38101 aagaaagtta aagagagaag atttgatgtc tttatgggaa atggcttatt cacaacttaa
    38161 tccagtttgg aaacagtatg atgctcccta ttatgatgat tatcagtatt tttcaaattt
    38221 taaagaattc gaactacaaa aatcagaatc cattttaagc aactcaaatc gccttggtat
    38281 ttttgttgat gataaactag ttgggactgt ttcgcgttat tgggtatgta aacaaacaag
    38341 atggatggaa ttgggaattg gtatttatga taaaaaattc tggaacactg gtattgggaa
    38401 agttgctatg ttgcagtgga tagataggac gtttcaggat tacttggagt tggagcatct
    38461 gggtttgaca acttggtcag ggaatcttgg tatgatgaaa cttgctgaaa aattaagaat
    38521 gaaaaaagaa gctcatattc caaaagttcg ttattatcaa ggtaaatatt ttgatagtat
    38581 taaatatggt attttgagag aagactggga gaaaataaat gacggttatt atcaaatcaa
    38641 tggaaactcc taaagagata gaaggtaaat cccttgttca ctggcaaatg tggagagagg
    38701 cttatgatga ccttttgcct gcagaatttc aggagacaat gacattagaa agatgtcgac
    38761 tctttagtca aaagtatcca gaaaatacat tgattgcgat aggtgatctg aaggtagttg
    38821 gttttatcag ttatggtaac tttcgtgatg agactatgca agctggtgaa attattgctt
    38881 tatatgtttt aaaagactat tatggaaaag gtatcgcaca aaagttaatg aaagcagctt
    38941 tgactgctct taatcatttt tctgaaattt tcttatgggt attgaaagat aacaagcgcg
    39001 ccattgcttt ctatcaaaaa atgggtttta cttttgatgg acaagaaaaa atacttgaac
    39061 ttggaaagcc tataaaggaa aaacgaatgg tgttctattc taaataa
//
LOCUS       DAVKBK010000016        38457 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVKBK010000016 DAVKBK010000000
VERSION     DAVKBK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.016"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            221..502
                     /locus_tag="VWX69_000867"
     CDS             221..502
                     /locus_tag="VWX69_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU9192236.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            634..1578
                     /gene="manA"
                     /locus_tag="VWX69_000868"
     CDS             634..1578
                     /gene="manA"
                     /locus_tag="VWX69_000868"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU9192237.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1600..3075)
                     /locus_tag="VWX69_000869"
     CDS             complement(1600..3075)
                     /locus_tag="VWX69_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEU9192238.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMNFLVPNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLE"
     gene            3241..3405
                     /locus_tag="VWX69_000870"
     CDS             3241..3405
                     /locus_tag="VWX69_000870"
                     /inference="COORDINATES: protein motif:HMM:NF024803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU9192239.1"
                     /translation="MVPLKSENGYRTYSQEDLERLQVILYYKYLGFSLEKIAELLKEE
                     RTDLLLHLTR"
     gene            3406..3912
                     /locus_tag="VWX69_000871"
     CDS             3406..3912
                     /locus_tag="VWX69_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TipAS antibiotic-recognition domain-containing
                     protein"
                     /protein_id="HEU9192240.1"
                     /translation="MDYLTRERQHLDTLISTLQKTIQEQKGERKMTIEEKFTGFSYQD
                     NQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAFNQVFQTLAQNLQVGLPATATENQ
                     EQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEFKENIDKFGSETAQYTSDAIAAYV
                     QTNAEKIG"
     gene            complement(3932..4387)
                     /locus_tag="VWX69_000872"
     CDS             complement(3932..4387)
                     /locus_tag="VWX69_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9192241.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4407..5582)
                     /locus_tag="VWX69_000873"
     CDS             complement(4407..5582)
                     /locus_tag="VWX69_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9192242.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFTGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5641..6486)
                     /locus_tag="VWX69_000874"
     CDS             complement(5641..6486)
                     /locus_tag="VWX69_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9192243.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6611..7168
                     /locus_tag="VWX69_000875"
     CDS             6611..7168
                     /locus_tag="VWX69_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9192244.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7187..7654
                     /locus_tag="VWX69_000876"
     CDS             7187..7654
                     /locus_tag="VWX69_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU9192245.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7743..8372
                     /gene="upp"
                     /locus_tag="VWX69_000877"
     CDS             7743..8372
                     /gene="upp"
                     /locus_tag="VWX69_000877"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU9192246.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8546..9136
                     /gene="clpP"
                     /locus_tag="VWX69_000878"
     CDS             8546..9136
                     /gene="clpP"
                     /locus_tag="VWX69_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU9192247.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9215..9463
                     /locus_tag="VWX69_000879"
     CDS             9215..9463
                     /locus_tag="VWX69_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU9192248.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9564..10724
                     /locus_tag="VWX69_000880"
     CDS             9564..10724
                     /locus_tag="VWX69_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9192249.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10992..11861
                     /locus_tag="VWX69_000881"
     CDS             10992..11861
                     /locus_tag="VWX69_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9192250.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11865..12821
                     /locus_tag="VWX69_000882"
     CDS             11865..12821
                     /locus_tag="VWX69_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9192251.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12821..13585
                     /locus_tag="VWX69_000883"
     CDS             12821..13585
                     /locus_tag="VWX69_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192252.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13585..14295
                     /locus_tag="VWX69_000884"
     CDS             13585..14295
                     /locus_tag="VWX69_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192253.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14709..15365
                     /locus_tag="VWX69_000885"
                     /pseudo
     CDS             14709..15365
                     /locus_tag="VWX69_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
     gene            15473..16568
                     /gene="prfB"
                     /locus_tag="VWX69_000886"
     CDS             join(15473..15544,15546..16568)
                     /gene="prfB"
                     /locus_tag="VWX69_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU9192254.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16586..17278
                     /gene="ftsE"
                     /locus_tag="VWX69_000887"
     CDS             16586..17278
                     /gene="ftsE"
                     /locus_tag="VWX69_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU9192255.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17271..18197
                     /locus_tag="VWX69_000888"
     CDS             17271..18197
                     /locus_tag="VWX69_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9192256.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            18483..20663
                     /locus_tag="VWX69_000889"
     CDS             18483..20663
                     /locus_tag="VWX69_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9192257.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20715..21530
                     /locus_tag="VWX69_000890"
     CDS             20715..21530
                     /locus_tag="VWX69_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9192258.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21670..23013
                     /locus_tag="VWX69_000891"
     CDS             21670..23013
                     /locus_tag="VWX69_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9192259.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23229..24419
                     /locus_tag="VWX69_000892"
     CDS             23229..24419
                     /locus_tag="VWX69_000892"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU9192260.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSEEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIKK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24972..25907
                     /locus_tag="VWX69_000893"
     CDS             24972..25907
                     /locus_tag="VWX69_000893"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU9192261.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25941..26978
                     /locus_tag="VWX69_000894"
     CDS             25941..26978
                     /locus_tag="VWX69_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU9192262.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27151..27756
                     /locus_tag="VWX69_000895"
     CDS             27151..27756
                     /locus_tag="VWX69_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU9192263.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELTAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27913..28443
                     /locus_tag="VWX69_000896"
     CDS             27913..28443
                     /locus_tag="VWX69_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU9192264.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28464..29366
                     /locus_tag="VWX69_000897"
     CDS             28464..29366
                     /locus_tag="VWX69_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HEU9192265.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVSCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDID
                     AACGQLRFNTMKRDRQKAVAAVNP"
     gene            29366..29848
                     /locus_tag="VWX69_000898"
     CDS             29366..29848
                     /locus_tag="VWX69_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9192266.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQPL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29850..31391
                     /locus_tag="VWX69_000899"
     CDS             29850..31391
                     /locus_tag="VWX69_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9192267.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31447..32250)
                     /locus_tag="VWX69_000900"
     CDS             complement(31447..32250)
                     /locus_tag="VWX69_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU9192268.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32334..32547)
                     /locus_tag="VWX69_000901"
                     /pseudo
     CDS             complement(32334..32547)
                     /locus_tag="VWX69_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(33026..33235)
                     /locus_tag="VWX69_000902"
     CDS             complement(33026..33235)
                     /locus_tag="VWX69_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192269.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33405..33677
                     /gene="rpsP"
                     /locus_tag="VWX69_000903"
     CDS             33405..33677
                     /gene="rpsP"
                     /locus_tag="VWX69_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU9192270.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33697..33936
                     /locus_tag="VWX69_000904"
     CDS             33697..33936
                     /locus_tag="VWX69_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU9192271.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34513..35301
                     /locus_tag="VWX69_000905"
     CDS             34513..35301
                     /locus_tag="VWX69_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9192272.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPKMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            35332..35850
                     /gene="rimM"
                     /locus_tag="VWX69_000906"
     CDS             35332..35850
                     /gene="rimM"
                     /locus_tag="VWX69_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU9192273.1"
                     /translation="MNYFNIGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            35840..36559
                     /gene="trmD"
                     /locus_tag="VWX69_000907"
     CDS             35840..36559
                     /gene="trmD"
                     /locus_tag="VWX69_000907"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU9192274.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDDPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36571..36909
                     /locus_tag="VWX69_000908"
     CDS             36571..36909
                     /locus_tag="VWX69_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192275.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(36940..37260)
                     /locus_tag="VWX69_000909"
     CDS             complement(36940..37260)
                     /locus_tag="VWX69_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192276.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAKKNR
                     FKKE"
     gene            37358..37573
                     /locus_tag="VWX69_000910"
     CDS             37358..37573
                     /locus_tag="VWX69_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU9192277.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(37642..37728)
                     /locus_tag="VWX69_000911"
                     /pseudo
     CDS             complement(37642..37728)
                     /locus_tag="VWX69_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(37779..38315)
                     /locus_tag="VWX69_000912"
     CDS             complement(37779..38315)
                     /locus_tag="VWX69_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU9192278.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
BASE COUNT        11832 a         7081 c         8339 g        11205 t
ORIGIN      
        1 acattgttag aaatcgattt gactgtcctg atcgatttgc cctgttcttg tttcgtttta
       61 ctatagaacg atttgaaggc gtttatgata tttagctgta cgagagtctt taaaaagtgt
      121 tttgatggtt tggatttctt ctttagttga tttcatatca ctattatata atgctttttg
      181 attttagtat agtattatcg tagaaaatgg actcggtgct atggatacac cggatgagaa
      241 tggttatgta gcagatgact atcggattac ttacttagag gcccacatca aggccatgcg
      301 agatgccatt tacaaagacg gggttgactt gcttggttat acgacatggg gctgtatcga
      361 ttcggtttca gctggcacag gggaaatgaa taagcgctat ggttttatct atgtagatcg
      421 agataatgta ggaaatggga ctctcaaacg tagcaagaag aagtccttct attggtacat
      481 gtcatttata gcaatggtgt aagcatcgag tagagcacat ttgtttacta tttttataaa
      541 atcttctccc tgctttataa gatgtaaaaa agagttcaat tcgaactctt tttttgctat
      601 aatgagggga gaaaaatcag acaggagatt aagatgtcag aaccattatt tttacaatca
      661 gttatgcaag aaaaaatctg gggtggtacc aagctacgtg atgagtttgg ctacgacatc
      721 ccaagtgaaa aagtcggaga gtactgggct atctcagctc atctaaatgg tgtttctaaa
      781 gttgccaatg gtcgttacga gggaacagat cttgctactt tgtatgcgga acaccgtgaa
      841 ttatttggca atcgtcctga gcctgtattt ccgcttttga ctaagatttt ggatgctaac
      901 gactggctca gcgttcaagt tcacccagac gatgcttatg gactagagca tgaaggcgaa
      961 cttggaaaaa cagaatgctg gtacatcatc gctgcggatg aaggttcaga gattatctac
     1021 ggccacaatg ccaagtcaaa agaagaactc cgccagcaaa tcgaggataa gaactgggat
     1081 gcgctgttga caaaagtgcc agttaaagca ggagatttct tctatgtacc aagcggtacc
     1141 atgcacgcta tcggggcggg tatcttgatt cttgaaaccc agcagtctag cgataccact
     1201 taccgtgtct atgactttga ccgtaaggat gacaagggca atttacgtga acttcacctt
     1261 gaaaaatcta tcgatgtctt gaacattggt gaacccgcaa atagccgtcc agtgacaatc
     1321 aaagcagatg atctacgttc cactctcctt gtatccaatg atttcttcgc agtttacaaa
     1381 tgggaaatta ctggaaaagt taactttgaa aagacagctg actacagctt gttgagtgtc
     1441 ttggctggtc aaggtcaact aactgttgac gggaaaaact atccaatcca aaaagggaga
     1501 cactttatcc taccaagtga tgttgaagct tggactctgg aagggcaaga tttagaatta
     1561 attgttagtc atccataaaa aagaaagggc ctgagttcat tactcaagtc ctttttgatt
     1621 acataaattg ggcgatgaag accacgatga tgattggaat gacggaacga agaaacgaag
     1681 aaggaagagc cagacttgga acagtccttg tttccatgct ctttcatcga gatggagttc
     1741 ctccattgca agagcctttt taaagatata gcctgtaaaa agtgaaaggt agagagctcc
     1801 aaatggcatg aggagattgg gaaccaagaa gttcatagcg tcaaagaagg tcttaccaaa
     1861 aatgtgaaca tccgccatga caccgtaaga tagggctgaa ggaatgccaa agacaaaggt
     1921 caaaattcct aaaataacac tccatttggc acgtttgctg ttatcctggt tggtgatatt
     1981 gcccacattg atctccagca tcacgacaga agaagtgaca gtcgcaaaga ggaagaggac
     2041 gtagaaaatg gttccaaaag gcatcttgtc aaagagttga ggcaagacga taaagagcaa
     2101 gctcggtccc ccttcagact ggatattgaa gggggaccga gcttggaaaa tggctagacc
     2161 tgccatgatg gatatcgaga tattcatggc tacgatggag attcctgact ggactagatt
     2221 ggttttcttg tccaagtaag aagcataggt caacatgact gtaaccccta gtgagagggc
     2281 aaagaaagat tgtcccagag catagaggag accagcgcta gtcagttttg aaaagtctgg
     2341 tttgaggaag taaagaaccc cttccatggc atttggcaaa ctgagagagc gaccgatgat
     2401 aacaacaaag atgataaaga gcaggggcat catgactttc gaagctcttt caatcccttt
     2461 ttgaacccca cgtgatacaa taaagatatt taataagata aaggctgctt gagctcctag
     2521 ggcaatggct ggatttgaaa tgattgaagt aaataactga gcataatcac ccgttccacc
     2581 aagttggaac aatttcccaa actcaatacc tagatagact agaatccatc ctccgataac
     2641 actgtaaaaa gataagagga taaagagggc aaaggcgcca atccaaccga taaagttgta
     2701 cttgttattc ttgcccagtt ttccaaaggt tttgatagcg gaaacgccag cactacggcc
     2761 aagggcaaac tcagccagca ggagagggaa accgattaaa atagtggaaa tgagaaagat
     2821 tagtaaaaag cctccaccgc cattagcagc agtcatgtag ggaaacttcc aaacggaacc
     2881 aagcccgatg accgagccag cagatgctag aataaagcca agtttcgacc cccattgtga
     2941 tttttctgac atagttaaac tctgatctcc tttttcaaaa taagaaaaag ctacttgagt
     3001 tgtcaaatag ccttctgttt gattgataga cttgactatc ctattatgtt ttctaaggtc
     3061 tgtcaagaaa acaattttca agttttcaca cctttctcaa aaacgcttga ctctgaccta
     3121 aggggagggg ttatactatc attgtaagga ggaaatcatg taccatataa aagaagctgc
     3181 gcagctttca ggtgtctctg tcaagaccct gccctgcatc actatgacaa gataggactc
     3241 ttggtcccct taaagtcgga aaacggctat cgaacctata gtcaagagga tttggaacgc
     3301 cttcaggtca ttctttacta caaatatcta ggcttttctt tagagaaaat agcagaactg
     3361 ttaaaggaag aaaggacaga tttattgctc catttgacta ggtagttgga ctatctaact
     3421 cgcgaaaggc aacatctgga taccttgatt tccaccttgc aaaaaactat tcaagaacaa
     3481 aaaggagaaa gaaaaatgac cattgaggaa aaattcacgg gatttagcta tcaagacaat
     3541 caaaaatacc accaagaagc ggtagagaaa tatggtcaag aagtcatggg acaagcgctc
     3601 gaacgccaaa aaggtcacga agacgaggct acggccgcct ttaaccaagt ctttcaaact
     3661 ttggcacaaa atcttcaagt tggtttacct gcaacagcaa ccgaaaacca ggagcaagca
     3721 gccaagctct tgcaagccat tcgcacttat ggatttgact gctctattga ggtattcggt
     3781 catatcggta aaggttacgt ctacaaccca gagtttaagg aaaacattga caagtttggt
     3841 tctgaaacag cccagtacac gtcagatgcc attgcggctt acgttcagac aaatgcagaa
     3901 aaaataggct aggaatttcc tagcctattt tttacttcaa atcataaagc cagtcgtcac
     3961 cgtttttgta gtaaaagaat tcactgagat cttcttctag aaacacacga agcatatcag
     4021 acatatcatc ggttgcaagt tttagatgag aaagattttc aaagtcctcc caccaaactt
     4081 tcccttcgtc tgaagactgg agttcaccag taaagtgttc tgtcttgtaa aaaaggacga
     4141 cataacgata atccttgtcg tcataccagt ttttgatacc acagagttgg ggtttggaaa
     4201 tgatcagacc agtttcttct ttcacttcac gaatgacagc atcgacaaag gattcgccac
     4261 gttcaacatg accaccagga aaagtaatgc cagaccagtc gggactaact cggtcttgga
     4321 ccaggacctt atctccgttt ttaatcatac acatgttaac aaattcgact gcctctcttc
     4381 tgttcattct tcacaacctt taatctttaa tcataatgca gacttcccgc cacccagccg
     4441 gtacagaggg cagaagtgat gttaaagcca cccgtgtggg cattgatatc cataacttcg
     4501 cctgtaaagt ggaggccagg taccagctta ctttcaaggg ttttaggatt gatttccttg
     4561 agactgactc cacccttggt aacaaaggac tttgcaaggg acatttttcc agttacagga
     4621 attttaagtt ctttaatgga ctggacaagt tgttctcgtt ccttttcagt cagttgtttg
     4681 actttttcag gatatccttg tacaaaaaat tcggccaagc gttctggtaa caaggttttt
     4741 aaagcgtttt tcaaggattt ttcccgattt tcttctagaa atgtaaccaa gtccttctca
     4801 gaaagttgag gcaaaacatc gagtgagaga acctccccac ctttgacaaa gctagacatg
     4861 cgtagggcag caggacctga caaaccaaag tgggtaaaga gtaaatcatg agtgatgaca
     4921 tgcttaccat aacttagggt cacatcgtcc agagaaatcc cttgtaaggc tttatgtgga
     4981 aaatctgtta ataaaggact ttcagcagcc tcaagatcgg tgatggtatg cttaaaatgg
     5041 cgagcaatct cgtgaccaaa accagtcgaa ccagtcgaag gataagactt accacctgtt
     5101 gtgacaatga gtttctcaca agtgaaggtt tgatccgctg acttaaggac aaactggtca
     5161 tctacttttt taacagaaac gatttctatt tgagtagcaa cttgaccacc tagttcggtg
     5221 attttctttt ccaaagcttc gataatagtc cgagacttgt cactggctgg aaagacgcgt
     5281 ccgtggtctt cgaccttaag tttaacacca ttttctgtaa aaaagttgat gatgtcatga
     5341 ttatcgaact gggagaaaac actgtaaaga aagcgtccgt ttccaggaat tccagctagc
     5401 aggttgtcta agctaccatt gttggtcaca ttgcaacgtc ccccaccagt cccagctaat
     5461 ttttttccaa gtttccgatt tttttcgatg aggagggttt tctgtccata aaagctactg
     5521 gaaatcgtag ccatcatacc agcaggtccc ccaccgatga caatagtatc aaaatgtttc
     5581 atagctctat tgtaccacaa aaaaacaaga gatgatggtc acctcttgtc aagaatgcaa
     5641 ttaatcaatt tcatagccca tcagcaaacc gccctcttct gcatagaaac tgcagagacc
     5701 agaggttggt agaattttaa tatccgcttg tgggaaggtt tcacggattc gctctgagag
     5761 ctgttgacaa catttttcgt tattgcgttg ggccatgaca atacggccac cagcatatcc
     5821 agcttttact aactcatcat aggcagcttg aactgatttc tttgatcccc ttgctttttg
     5881 tagcaattcg agagttccag tttcactagc ttttccgacc atacgaatgt tgagaaggcc
     5941 aacgaccgta ccgataagct tgctcaaacg gccgttcttc accaagttat cgactttggc
     6001 taggacaaag agcaacttag ttttttcttg ataggcagtg atagcttcaa ccacttcttc
     6061 aaaagacaag ccctggtcaa tcaagtcatt caatttttct acgagtaggt caacttcacc
     6121 accagcagat aaactatcaa tcacatgaat cttagtgtca ggatggtctt ctagataaat
     6181 attctttgct agttgagcac tattgtgact gccagaaagg gtacctgtga tggttactag
     6241 gaaaatgttt ttggcacctt caaatgctcg caaatagtca tctgggcttg gacaagccga
     6301 ttttgaagct tctgcagttg catacatggt ttccatcatt tggtcaatat cgagactggc
     6361 gtcatcaaca aagacctgat cagctacttg aatggttaag gggacactta caaaggttgt
     6421 gttaatagct ggtgttggca gttgacgata atcacaacca gagtcagcaa taattttcca
     6481 agtcatagaa attctccatc tttgtcagtt atacattgac aaaggttctg tcttttttta
     6541 caattatatc atgaaaaccc ttgaaacaaa agcatcatcc gtctgttgtg acaagtagaa
     6601 agaaaatgtt atgtctgaac gtagaatctc tgaaaagtct cttgaaaatc tcagaaaatc
     6661 aaaccaagaa tccaatttat taaccagaga agccattgaa acagccctct tgcaactctt
     6721 ggaaaaaaag gagctgacca agattagtat ttctgaattg gtcaaacgtg caggtgtttc
     6781 gcgtgcggcc ttttatcgca attatgactc caaagaggaa attttagaga gcgtctttaa
     6841 acgaactgtc cacaatatta tggaacagct gcatcattac gatttaaaga cagaccttta
     6901 tttggtttgg gttcaccttt tccgggaggc cagaaaggaa gctagagtga ttcaattggc
     6961 cttggattac catctggaaa aaatctttgt ccaagccatg caggaatttc tagaaaaata
     7021 ccatgggaaa tcaaaaggtg tcagctctta tcttcattcc ttctggagct cagccatcgt
     7081 ctctgtcctt ctaaaatgga tcaaggatgg catgaaggta ccagctgaaa agattgcaga
     7141 tttaggttta ccatttttta aaaaatagag aaaaaggaga aaagagatga ctgaaaaaag
     7201 actggcctgg gatgagtatt ttgcagccca agccctacta attgcgaatc gttccacttg
     7261 taaacgtgct aaagtgggcg cgattctggt aaaagataat aaggttattt ccactggtta
     7321 caatggttcg gtgtcaggga ctgagcattg tattgatcac gaatgtttgg tcattgaagg
     7381 ccactgtgtt cgcacccttc acgctgaggt caatgctatc cttcaaggtg ctgagcgtgg
     7441 tgttcccaaa ggctttacag cctatgtaac ccattttcct tgtctcaact gtacaaaaca
     7501 attgcttcag gtcggctgca agcgcgtggt ttatatcaac cagtaccgaa tggacgacta
     7561 cgcccaatac ctttatcaag aaaaagggac agaattgacc catttaccac ttgagacagt
     7621 acagacagct cttaaagagg ctgatctaat gtaaaaatta tcaaaaataa atggcttaga
     7681 aagattttta aaccgttttt tggtataata agaagaataa attgaaagaa ggaattccaa
     7741 aaatgggaaa aattgaagtt attaatcacc cactgattca acacaaattg tcaatcttgc
     7801 gtcgtacaga tacttctaca aaagcttttc gtgagctagt agatgagatt gcaatgttga
     7861 tggggtatga agtacttcgt gatcttccac tagaagatgt ggaaatcgaa acaccaatta
     7921 caaaaacagt tcaaaaacaa ttggcaggta agaaattggc catcgtccca atcttgcgtg
     7981 caggtatcgg gatggttgat ggtctcttga gcttggttcc agctgctaaa gttggccaca
     8041 tcggtatgta ccgtgatgaa gaaacacttc aaccagttga atacttggtg aaattgcctg
     8101 aggacattga ccaacgtcaa atttttatag tagacccaat gttggcaaca ggtggctcag
     8161 caatcttggc tgttgattct cttaaaaaac gtggcgcatc aaatatcaaa tttgtctgcc
     8221 ttgtatctgc tccagagggt gtaaaagccc ttcaagaagc tcatccagat gtagaaatct
     8281 ttacagcagc cttggatgaa cgtttgaacg aacacggtta tatcgttcca ggtcttggag
     8341 atgctggaga ccgcttgttc ggtacaaaat aagatcgaaa agaagaatga cttggaaaag
     8401 tatttccagt cacgaaagga ggttgggttt ttgtttctgt ctaatgaaag cagagcaaaa
     8461 atttgacctt ttttgaccaa gatattataa tagtcttatc ttcagtcatt tgaccaacaa
     8521 aattaaaact caaaaggaga aatgaatgat tcctgtagtt attgaacaaa caagccgtgg
     8581 agaacgttct tacgatattt actcacgtct tctcaaagac cgcatcatta tgctgacagg
     8641 tccggttgaa gacaatatgg ctaactctgt tattgcccaa ttgcttttct tggatgccca
     8701 agatagtaca aaagatattt acctttatgt caatacacca ggtggttctg tttcagctgg
     8761 tttggcaatc gtagatacca tgaactttat caaggcagat gtccaaacca ttgttatggg
     8821 aatggctgca tctatgggaa cagtcatcgc atcaagtgga gcaaaaggca aacgtttcat
     8881 gcttccaaat gctgaataca tgattcacca accaatgggc ggtacaggtg gtggtaccca
     8941 acaaactgat atggctatcg ctgcagaaca cttgctcaaa actcgtaata ccttggaaaa
     9001 aatcttggct gaaaattcag gtcagtcaat ggaaaaagtc catgcagatg cagaacgtga
     9061 taactggatg agcgcccagg aaacacttga atatggcttt attgatgaaa ttatggccaa
     9121 caattcattg aactaatgat gatagaaggc aaactcgact gggtttgctt tttttggtat
     9181 aatagggaga gatttcttag aaagaggatt tatcatgttt gaaaaagtca atcgctctgg
     9241 cttgattatc tatctttact ataatcgtga tgccaaaaaa ctgcaggatt atggagatat
     9301 tacctatcat tccaagaaac atcgttactt acaactctat gttccaactc aagaagtgga
     9361 gcaattggtc ggacgcttga gcaaggaaaa atttattaaa aaagttaggg tttgtcatat
     9421 ccaagagttg gaaacaccct ttgtgggcaa tctttatcga taggaaaacg ttatcatcga
     9481 aaaagttcaa ggaaaacatt gacaattttc tgataattcg gtatattctt aacagactat
     9541 ttaagaaata aggagacaaa aagatgaaga aaaaatttgc cctatcgttt gtggcgcttg
     9601 caagtgtagc acttcttgca gcctgtggag aagtgaagtc tggagcagtc aacactgctg
     9661 gtaactcagt agaggaaaag acaattaaaa tcgggtttaa ctttgaagaa tcaggttctt
     9721 tagctgcata cggaacagct gaacaaaaag gtgcccaatt ggctgttgat gaaatcaatg
     9781 ccgcaggtgg tatcgatgga aaacaaatcg aagtagtcga taaagataat aagtctgaaa
     9841 cagctgaggc tgcttcagtt acaactaacc ttgtaaccca atctaaagta tcagcagtcg
     9901 taggacctgc aacatctggt gcgactgcag ctgcggtagc gaacgctaca aaagcaggtg
     9961 ttcccttgat ctcaccaagt gcgactcaag atggattgac taaaggtcaa gattacctct
    10021 ttattggaac tttccaagat agcttccaag gaaaaattat ctcaaactat gtttctgaaa
    10081 aattaaatgc taagaaagtt gttctttaca ctgacaatgc cagtgactat gctaaaggga
    10141 ttgccaaatc tttccgcgag tcatacaagg gtgaaatcgt tgcagatgaa actttcgtag
    10201 caggtgacac agacttccaa gcagccctta caaaaatgaa agggaaagac tttgatgcta
    10261 tcgttgttcc tggttactat aatgaggctg gtaagattgt aaaccaagcg cgtggtatgg
    10321 gaattgacaa accaatcgtt ggtggtgatg gattcaacgg tgaggagttt gtacaacaag
    10381 caactgctga aaaagcatca aacatctact ttatctcagg cttctcaact actgtagaag
    10441 tttcagctaa agctaaagcc ttccttgacg cttaccgtgc taagtacaat gaagagcctt
    10501 caacatttgc agccttggct tatgattcag ttcaccttgt agcaaacgca gcaaaaggtg
    10561 ctaaaaattc aggtgaaatc aaggataacc ttgctaaaac aaaagatttt gaaggtgtaa
    10621 ctggtcaaac aagcttcgat gcagaccaca acacagtcaa aactgcttac atgatgacca
    10681 tgaacaatgg taaagttgaa gcagcagaag ttgtaaaacc ataatagaaa aatgttgaaa
    10741 tagggaatga gcctttgact cactccctgt ttcgatattt aatactcttc gaaaatctct
    10801 tcaaactgcg tcaacgtcgc cttggattat atatgtgact gacttcgtca gtcttatcta
    10861 caacctcaaa gcagtgcttt gagcaacctg cggctagttt cctagtttgc tctttgattt
    10921 tcattgagta taagaaccta tcaaaaagtg agggaaaccc ctcggaatta taaatagaaa
    10981 gagtgaatct tatgctccaa caactcgtaa atggtttgat tctaggtagt gtttacgcgc
    11041 tgttagccct aggatatacc atggtttacg gaattatcaa gctcatcaac ttcgcccatg
    11101 gtgatattta tatgatggga gcctttatcg gttatttctt gatcaattct ttccaaatga
    11161 atttctttgt agcgcttatt gtagctatgc tagcgacagc tattcttggt gtcgtgattg
    11221 agtttcttgc ttaccgacct ttgcgccact ctactcgtat tgctgttttg attacggcta
    11281 ttggggtttc tttcctattg gagtatggaa tggtctatct ggttggtgcc aatacccgtg
    11341 ccttccctca agcgattcaa acagttcgat atgatttggg accaattagc ttaacaaatg
    11401 tgcagttaat gattttggct atttccttga ttttgatgat tttgttacaa gtcattgtcc
    11461 aaaagactaa gatggggaaa gccatgcgtg cagtatcagt agatagcgac gcggcgcaat
    11521 tgatggggat caatgtaaac cgtacgatta gctttacctt cgctttgggt tctgctcttg
    11581 cgggtgcggc tggtgttctg attgctcttt attataactc tcttgagcct ttgatggggg
    11641 ttactccagg tcttaaatct ttcgttgccg cagtacttgg tggtatcgga attattcctg
    11701 gtgcggctct tggtggcttt gtgattggtc tattggaaac ctttgcgact gcctttggga
    11761 tgtcagattt ccgtgatgcc attgtttatg gaatcttgtt gttgatcttg attgtccgcc
    11821 cagctggtat ccttggtaag aatgtgaaag agaaggtgta aacgatgaag gaaaatttaa
    11881 aagttaatat tctatggtta ctccttttgt tagctggcta tagcttgatt agtgtactgg
    11941 tttcagtcgg agtacttaat ctattctatg tacagatttt acagcaaatt ggaattaata
    12001 ttattttggc tgttggtctc aacttaatcg ttggtttttc aggacaattt tcacttggtc
    12061 atgctggttt catggcgatt ggtgcctatg cagcagctat tattggttct aaattaccaa
    12121 cctacggtgc cttctttgga gctatgcttg taggggcttt gctttcagga gcagttgcct
    12181 tacttgtcgg cattccaacc ttgcgcttga agggggacta tcttgcggta gcaactctgg
    12241 gtgtttctga aattatccgt atctttatca tcaatggtgg aagccttaca aatggtgcgg
    12301 caggtatctt agggattcct aactttacaa cttggcaaat ggtttacttc tttgtcgtga
    12361 ttacaaccat tgcaaccttg aacttcttgc gtagcccaat tggtcgttca accctctctg
    12421 ttcgtgaaga tgaaatcgct gctgagtcag ttggggttaa tacgactaaa attaaaatca
    12481 tcgcttttgt ctttggtgcc attactgcaa gtattgctgg gtcacttcag gcaggattta
    12541 tcgggtctgt tgtaccgaaa gattacacct tcatcaactc aatcaacgtt ttgattattg
    12601 ttgtatttgg tggactcggt tccattacag gtgcgattgt ttcggctatt gttctgggaa
    12661 ttttgaatat gcttctccaa gatgttgcta gtgtgcgtat gattatttac gctttggcct
    12721 tggtattggt aatgattttc agaccaggtg gactccttgg aacatgggaa ctgagcctat
    12781 cacgtttctt taaaaaatct aagaaggagg aacaaaacta atggcattac ttgaagtaaa
    12841 acagttaacc aaacattttg gtggtctaac agctgttgga gatgtgactc ttgaattgaa
    12901 cgaaggggaa ctggttggat taatcggtcc aaacggagct gggaaaacca cccttttcaa
    12961 ccttttgacc ggtgtttatg aaccaagcga gggaacagta accctagatg gtcacctttt
    13021 gaatgggaaa tcaccttata agattgcctc tttgggactt ggacgtactt tccaaaatat
    13081 ccgtctcttt aaagatttaa cagttttaga caatgttttg attgcttttg gaaaccatca
    13141 caaacaacat gtttttacta gtttcttacg cttaccagct ttttacaaga gtgaaaaaga
    13201 attaaaggct aaagctttgg aattgttgaa aatctttgat ttagatggtg atgcagagac
    13261 tcttgctaaa aatctttcct acggacaaca acgtcgtttg gaaattgttc gtgcccttgc
    13321 tacggaacct aaaattctct tcttagatga accagcagca ggtatgaacc cacaggaaac
    13381 agccgaattg actgagttaa ttcgtcgtat caaagatgaa tttaagatta caatcatgtt
    13441 gattgaacac gatatgaatc tggtcatgga agtaacagaa cgtatctacg tacttgaata
    13501 tggccgttta attgctcaag gaactccaga cgaaattaag accaataaac gcgttatcga
    13561 agcttatcta ggaggtgaag cctaatgtct atgttaaaag ttgaaaatct ttctgtgcat
    13621 tacggtatga tccaagcagt ccgtgatgta agctttgaag ttaatgaagg agaagttgtt
    13681 tcccttatcg gtgccaacgg tgcaggtaag acaactattc ttcgcacctt gtcaggtttg
    13741 gttcgaccaa gttcaggaaa gattgaattt ttaggtcaag aaatccaaaa aatgccagct
    13801 cagaaaattg tggcaggtgg tctttcacaa gttccagaag gacgccacgt ctttcctggc
    13861 ttgactgtta tggaaaatct tgaaatggga gctttcttaa agaaaaatcg tgaagaaaat
    13921 caagctaact tgaagaaggt tttctcacgc tttcctcgtc ttgaagaacg taagaaccaa
    13981 gatgcagcta ctctttcagg aggggaacaa caaatgcttg ccatgggacg cgctcttatg
    14041 tcaacaccaa aacttcttct tttagatgaa ccatcaatgg gacttgcccc aatcttcatc
    14101 caagagattt ttgatatcat tcaagatatt cagaagcaag gaacaaccgt cctcttgatt
    14161 gaacaaaatg ccaataaagc acttgcaatc tctgaccgag gatatgtact ggaaacaggg
    14221 aaaatcgtcc tatcaggaac aggaaaagaa ctcgcctcat cagaagaagt cagaaaagca
    14281 tatctaggtg gctaaaacaa tccagtggat tgttttagtc ggcagatgaa gattacgaag
    14341 taatcatcat tatagtctgg gagactagtt taggttgcag ataaagattg cgaagcaatc
    14401 atcaaatcca gtggattgtt ttagtcggca gatggagatt acgaagtaat catcaatata
    14461 gtccggggga cctttttagt cggtagattg agattgcaaa caaatctgca tctacattga
    14521 aagcttaatt tctaataatt gaaaaaatcg aatgaaaaat ttcttacctt cattcacaga
    14581 gctcgatttc agagctcttt ttgctagctt attcatactt ttctgaattt cgaaaaagaa
    14641 atgtaagcgt ttgatagatt tacaaaaaga ttgtataata gggataagaa tagaaaagga
    14701 gaagtctcat ggcagttaaa gattttatga cccgcaaggt agtttatatt agtccagata
    14761 caacagtatc tcatgcagca gatttgatga gagagcaagg tttgcaccgt ctgcctgtta
    14821 tcgaaaatga tcaattagtt ggtttggtga ctgagggaac cattgcacaa gcaagtccat
    14881 ctaaagcaac aagtctttct atctatgaga tgaattatct tctgaataag acaaaagtaa
    14941 aagatgtcat gattcgcgat gttgtcactg tctcaggcta tgctagtcta taagatgcaa
    15001 cttatctgat gttgaaaaat aagattagta ttctccctgt cgtagataac catcaagtat
    15061 acggagttat tactgaccgt gacgttttcc aagcctttct tgaaattgca ggttatggcg
    15121 aagaagggat tcgtgtacgc tttgttacag aagatgaagt tggtgttctt ggaaaaattg
    15181 tttctttgat tgtagaagaa aatttgaata tctcccatac agtcaatatt ccgcgtaagg
    15241 atggtaaggt gattatcgaa gtgcaaatcg atggatcaat tgatttacca gccttgaaag
    15301 aaaaatttga agcaaatggt attcaagtgg aagaaatcgc tcgcacttca gcaaaagtct
    15361 tgtaagaagg gaagcccaaa ggcttctttt ttcatgaaaa ggggattaga gaaaaagatg
    15421 gaaagaaatg ataaaatatg ctataatgaa ataatgtaaa aaaggagtat ttatggacat
    15481 ttcagtaatt cgtcagaaaa ttgacgcaaa tcgtgaaaaa ttagcttctt tcagggggtc
    15541 tctttgacct cgaagggcta gaggaggaga ttgccatctt ggaaaacaag atgacagaac
    15601 ctgatttttg gaacgataat attgcagccc aaaaaacgtc gcaagaatta aatgaattaa
    15661 aaaacactta caataccttc cataagatgg aagagttgca ggatgaagtc gaaattttat
    15721 tggatttttt ggctgaagac gagtcagtgc atgatgaact ggtagcgcag ttagccgaac
    15781 ttgataagat aatgaccagc tacgagatga ctctactctt gtcagaacct tatgaccaca
    15841 acaatgccat cttggaaatc catccaggtt ctggtggtac tgaggcgcag gactggggtg
    15901 atatgttgct tcgtatgtat actcgttatg gtaatgctaa aggctttaaa gtggaagtgt
    15961 tggattacca agcaggtgat gaggctggta ttaagtcggt aactttatca tttgaagggc
    16021 ctaatgccta tggtctcctc aagtcagaaa tgggtgttca ccgcttagtg cgaatctcac
    16081 catttgactc tgccaaacgt cgccatacct ctttcacatc tgtagaagtg atgccagaat
    16141 tggatgatac tattgaagtg gaaatccgtg aagatgatat caagatggat accttccgtt
    16201 caggtggtgc cggtggacaa aacgtcaata aggtttcaac aggtgtacgt ttaacccaca
    16261 ttccaactgg aattgttgtc caatcaacag tggatcgtac ccagtatgga aatagagatc
    16321 gtgccatgaa gatgttgcag gctaagctct atcaaatgga gcaagagaag aaggctgcag
    16381 aggtagattc tctcaaaggt gagaaaaagg agatcacttg gggaagccaa atccgttctt
    16441 atgtcttcac gccttatact atggtaaaag atcaccgaac tagctttgag gttgctcagg
    16501 tagataaggt tatggatggg gacttagatg gttttatcga tgcttatctc aagtggcgaa
    16561 ttagctaaga tagaaaggaa ctcacatgtc aattattgaa atgagagatg tcgttaaaaa
    16621 atacgacaac ggaacgactg ctctacgcgg tgtttcggtt agcgttcaac cgggggaatt
    16681 tgcttacatc gtaggacctt caggagcagg gaagtcaact tttattcgtt ctctgtatcg
    16741 tgaagtaaaa atcgataaag gaagcctatc agttgctggt tttaatctgg ttaagatcaa
    16801 aaagaaagat atcccgcttc tacgtcgtag tgttggggtt gtcttccagg attataaatt
    16861 gttaccaaag aaaactgtct atgaaaatat tgcttacgct atggaagtaa tcggggaaaa
    16921 tcgccgtaat atcaaaagac gagtgatgga agttttggac ttggttggat tgaagcataa
    16981 ggttcgttct ttcccaaatg aactctcagg tggggagcaa cagcggattg cgattgcgcg
    17041 tgcaattgta aataatccca aagtattgat agctgatgag ccaacaggaa atctggatcc
    17101 ggataattca tgggaaatta tgaatctttt ggaacggatt aacctacaag gaacaactat
    17161 tttgatggcg actcataata gccagattgt aaataccttg cgccaccgtg tcattgccat
    17221 tgaaaatggc cgtgtcgttc gtgacgaatc aaaaggagag tatggatacg atgattagta
    17281 gattttttcg ccatttattt gaagccttaa aaagtttgaa acgaaatggt tggatgacag
    17341 tagctgctgt cagttcagtc atgattactt tgaccttggt ggcaatattt gcatctgtta
    17401 ttttcaatac agcgaaacta gctacagata ttgaaaataa tgtccgtgta gtagtttata
    17461 tccgaaagga tgtggaagat aatagtcaga caattgaaaa agaaggtcaa actgttacaa
    17521 ataatgacta ccacaaggta tatgattctt tgaagaacat gtctacggtt aaaagtgtta
    17581 ccttttcaag taaagaagaa caatatgaaa aattaaccga gataatggga gataactgga
    17641 aaatctttga aggagatgcc aatcctctct atgatgccta tattgtagag gcaaacactc
    17701 caaatgatgt aaaaactata gccgaagatg ctaaaaaaat tgaaggtgtc tctgaggttc
    17761 aagatggcgg tgccaataca gaaagactct tcaagttagc ttcatttatc cgtgtttggg
    17821 gactagggat tgctgctttg ttaattttta tcgcagtttt cttgatttca aataccattc
    17881 gtattaccat tatttcccgc agtcgcgaaa ttcaaatcat gcgcttggtc ggagctaaaa
    17941 acagttatat ccgtggaccg ttcttgttag aaggagcctt tatcggttta ttgggagcta
    18001 tcgcaccatc tgttttggtc tttattgttt atcaaattgt ttaccaatct gtcaacaaat
    18061 cgttggtagg gcaaaatcta tccatgatta gtccagattt atttagtccg ttgatgattg
    18121 ccctactatt tgtgattggg gttttcattg gttcattggg atcaggaata tccatgcgcc
    18181 gattcttgaa ggtttaggta aaatagctgc ttttatgagg agattgtaaa atctcctttt
    18241 ttgctacaag agtttttgaa aagagatgcg cagaagaaaa gagcttccaa agaagtcccc
    18301 cagagaagac ttcttgatgg ctaatttgaa cttgaaattt ggcgcactag aaatttttta
    18361 gaaaaaagtg taattttttt ataaaagcct ttacaaaaaa aattaaagtg gtataattaa
    18421 atcatagaaa gtgcaaacgt tttcgtaaaa cgtttgccta aataaaaata aaggagattt
    18481 gaatgatgaa agatacattc aaaaatgtct tgtctttcga attttggcaa aaattcggta
    18541 aggctttgat ggtagttatc gcggttatgc cggctgctgg tttgatgatt tcaatcggta
    18601 agtctatcgt gatgattaac ccaacctttg caccacttgt catcacaggt ggaattcttg
    18661 agcaaatcgg ttggggggtt atcggtaacc ttcacatttt gtttgcccta gccattggag
    18721 gaagctgggc taaagaacgt gctggtggtg ctttcgccgc tggtcttgcc ttcatcttga
    18781 ttaaccgtat cactggtaca atctttggtg tatcaggcga tatgttgaaa aatccagatg
    18841 ctatggtaac tactttcttt ggtggttcaa tcaaagttgc tgattacttt atcagtgttc
    18901 ttgaagctcc agccttgaac atgggggtat tcgtagggat tatctcaggt tttgtagggg
    18961 caactgctta caacaaatac tacaacttcc gtaaacttcc tgatgcactt tcattcttca
    19021 acgggaaacg tttcgtacca tttgtagtta ttcttcgttc agcaatcgct gcaattctac
    19081 ttgctgcttt ctggccagta gttcaaacag gtatcaataa cttcggtatc tggattgcca
    19141 actcacaaga aactgctcca attcttgcac cattcttgta tggtactttg gaacgtttgc
    19201 tcttgccatt tggtcttcac cacatgttga ctatcccaat gaactacaca gctcttggtg
    19261 gtacttatga cattttaact ggtgcagcta aaggtactca agtattcggt caagacccac
    19321 tatggcttgc atgggtaaca gaccttgtaa accttaaagg tactgatgct agtcaatatc
    19381 aacacttgtt agatacagta catccagctc gtttcaaagt tggacaaatg atcggttcat
    19441 tcggtatctt gatgggtgtg attgttgcta tctaccgtaa tgttgatgct gacaagaaac
    19501 ataaatacaa aggtatgatg attgcaacag ctcttgcaac attcttgaca ggggttactg
    19561 aaccaatcga atacatgttc atgttcatcg caacacctat gtatcttgtt tactcacttg
    19621 ttcaaggtgc tgccttcgct atggctgacg tcgtaaacct acgtatgcac tcattcggtt
    19681 caatcgagtt cttgactcgt acacctattg caatcagtgc tggtattggt atggatatcg
    19741 ttaacttcgt ttgggtaact gttctctttg ctgtaatcat gtactttatc gcaaacttca
    19801 tgattcaaaa attcaactac gcaactccag ggcgcaacgg aaactacgaa actgctgaag
    19861 gttcagaaga aaccagcagc gaagtgaaag ttgcagcagg ctctcaagct gtaaacatta
    19921 tcaaccttct tggtggacgt gtaaacatcg ttgatgttga tgcatgtatg actcgtcttc
    19981 gtgtaactgt taaagatgca gataaagtag gaaatgcaga gcaatggaaa gcagaaggag
    20041 ctatgggtct tgtgatgaaa ggacaagggg ttcaagctat ctacggtcca aaagctgaca
    20101 ttttgaaatc tgatatccaa gatatccttg attcaggtga aatcattcct gaaactcttc
    20161 caagccaaat gactgaagca caacaaaaca ctgttcactt caaagatctt actgaggaag
    20221 tttactcagt agcagacggt caagttgttg ctttggaaca agtaaaggat ccagtatttg
    20281 ctcaaaaaat gatgggtgat ggatttgcag tagaacctgc aaatggaaac attgtatctc
    20341 cagtttcagg tactgtgtca agcatcttcc caacaaaaca tgcttttggt attgtgacgg
    20401 aagcaggtct tgaagtattg gttcacattg gtttggacac agtaagtctt gaaggtaaac
    20461 catttacagt tcatgttgct gaaggacaaa aagttgcagc aggagatctc cttgtcacag
    20521 ctgacttgga tgctatccgt gcagcaggac gtgaaacttc aacagtagtt gtcttcacaa
    20581 atggtgatgc aattaaatca gttaaattag aaaaaacagg ttctcttgca gctaaaacag
    20641 cagttgctaa agtagaattg taatatactt gaggttggaa gctgtattcc aacctcttat
    20701 tttgggagaa aagaatgaaa tttttaacac tcaatactca cagttggatg gagaaagaag
    20761 cagaggaaaa attccagatt ttgcttgaag atattcttga aaaggactat gatttgattt
    20821 gtttccaaga aatcaatcag gagatgacct cgtcagaggt ggaggttaat gacctttatc
    20881 aagctttgcc agcagctgag cctattcacc aagaccatta tgttagactc ttggttgaaa
    20941 agttgttaga gcaagggaaa aattactact ggacctgggc ttataaccat atcggctatg
    21001 accgctacca cgaaggtgtg gctatcttgt ctaaaacacc tattgaagcc agagaaattt
    21061 tggtttcaga tgtggatgat ccaacagact atcatactcg ccgtgttgcc ctagctgaaa
    21121 ctgtagtcga tggcaaggag ctagcagttg ccagtgttca tctctcttgg tgggataaag
    21181 gtttccaaga agaatgggca cgatttgagg ctgtcttgaa aaaattgaac aagccacttt
    21241 tactagctgg agattttaac aacccagcag gtcaggaagg ttaccaagct attttagcta
    21301 gtccattagg cttacaagac gcatttgaag ttgctcaaga gaaaagtggt agctatactg
    21361 ttccgcctga aattgatggc tggaaaggga acactgaacc ccttcgaatc gattatgtct
    21421 ttactaccaa agagttagcg gtggaaaatt tacatgtcgt atttgatggt aacaagagtc
    21481 cacaagtgag tgatcactat ggcttgaatg ctatattaaa ctggaaataa taactgaaaa
    21541 gaggttggaa ctataaaatt ccagcctttt cttactagag aagctactgg aaatagccta
    21601 aataagtgag actactgtaa tggaataaaa tatggtataa ttgataaggt agatagaatc
    21661 gaggatgtta tgtcatttac gaaatttcaa tttaaaaact atattagaga agccttgaag
    21721 gagttaaaat ttacaactcc aacagaggtg caagacaagt tgattcctat tgttttggca
    21781 ggtcgtgacc tagtaggaga atcaaaaaca ggttcaggta agactcatac tttcttgtta
    21841 ccgattttcc agcaattaga tgaagctagc gatagtgtac aagcagtgat tactgcaccg
    21901 agtcgtgagt tggctactca aatttaccaa gtagcgcgtc agatttcagc tcactcagat
    21961 gtcgaagttc gtgtggttaa ttatgtgggt ggtacggata aggctcgcca gattgagaaa
    22021 ttggcaagca atcagcctca tattgttatt ggaacaccag gccgtatcta cgacttggtt
    22081 aaatctggtg atttagctat tcataaagcc aagacatttg ttgttgatga agcagatatg
    22141 accttggata tgggattctt ggaaactgtt gataagattg ctggcagtct tccaaaagac
    22201 ttgcaattca tggtcttctc agcgactatc ccacaaaaac tgcaaccatt cttgaaaaaa
    22261 tacttatcaa atcctgttat ggagaaaatt aagaccaaaa cggttatttc tgacaccatt
    22321 gataattggt tgatttcgac caagggacat gataagaatg ctcaaattta ccagttgact
    22381 cagttgatgc agccgtattt ggcaatgatt tttgttaaca ctaaaacacg tgctgatgaa
    22441 ttgcattcat atctgactgc tcaaggcttg aaggttgcaa aaatccatgg agatattgcc
    22501 cctcgtgaac gcaagcgaat catgaatcag gtgcaaaatc tggattttga gtatattgtc
    22561 gcaacagatt tggcagcgcg tgggattgac attgaaggtg tcagccatgt catcaatgat
    22621 gccattccgc aagacttatc tttttttgtt catcgtgttg gtcgtactgg acgaaatggc
    22681 ctaccaggta cagctattac cctttatcag ccaagtgatg actcggatat ccgtgagttg
    22741 gagaaattgg gaatcaagtt tagtcctaag atggtcaaag acggggaatt tcaagatacc
    22801 tatgaccgtg atcgtcgtgc caaccgtgag aaaaaacaag ataaacttga tatcgaaatg
    22861 attggtttgg ttaaaaagaa aaagaaaaaa gtcaaaccgg gttataagaa gaaaattcaa
    22921 tgggcggttg atgaaaagcg ccgtaaaacc aagcgtgctg aaaatcgcgc tcgcggtcgt
    22981 gcagagcgta aagctaaacg ccaaacattt taatagaaat tgttggagta ttgagctcca
    23041 acttttttat ttatgagaac gaactatcta aaccgaaaca ctacattaaa gactgcaaat
    23101 tgcgattaaa aatggtataa tgataaagtt atatagtccc gataagatgg taggtattta
    23161 ttacgaagag ttttcctatc agtactttgt aactctataa caatattttt taaggggggg
    23221 acatttttat gtcagagcgt aaattattca cgtctgaatc tgtatctgag gggcatccgg
    23281 ataagattgc agaccaaatt tcagatgcga ttttggatgc tattttagca aaggatccag
    23341 aggcgcacgt tgctgctgaa acagctgtat atactggttc tgtccacgtt tttggtgaaa
    23401 tttctacaaa tgcctatgtg gatattaacc gtgtggttcg tgataccatt gcagagattg
    23461 gttataccaa tacagaatat ggattttctg ctgagacggt gggagtacac ccatctttgg
    23521 tggaacaatc tcctgacatc gctcaaggtg ttaacgaagc cttggaggtt cgtggaaatg
    23581 ctgatcaaga tccactggac ttgattggag caggtgacca agggctcatg tttggatttg
    23641 cagtagatga aacagaagag ctcatgccat tgccaattgc actcagtcat aaattggttc
    23701 gtcgtctggc agaacttcgt aagtctgaag aaattagcta tctccgtcca gatgcaaaat
    23761 cacaagttac agttgagtac gatgaaaatg accgtccggt acgtgtagat acagtcgtta
    23821 tttctactca gcatgatcca gaggccacta atgaacaaat ccatcaagat gtgattaaaa
    23881 aggtcatcaa agaagttatt ccatcttctt atcttgatga taagacaaaa ttctttatca
    23941 atccgacagg tcgttttgta atcggtggtc ctcaagggga ctcaggtttg actggtcgta
    24001 agattattgt agatacttat ggtggctact ctcgtcatgg tggtggtgcc ttctctggta
    24061 aagatgcgac taaggtggat cgttcagcct cttatgcggc tcgctatatt gccaagaata
    24121 tcgttgcagc agaccttgct aagaaggcag aagtgcagtt ggcctatgct atcggtgttg
    24181 cgcaacctgt ttctgttcgt atcgatactt tcggtacagg aacagtagct gaaagtcaac
    24241 ttgaaaaagc ggctcgtcaa atctttgacc ttcgccctgc agggattatc caaatgctgg
    24301 acctcaagcg tccaatttac cgtcaaacat cggcttacgg tcacatggga cgtacagata
    24361 ttgatcttcc atgggaacgt ttggataagg tagatgcttt gaaagaagca gtaaaataag
    24421 attttaagag gggaacgtcc tctctttttt atagttttta actatactgg gatactgttc
    24481 tgaaaatcca ttttgtgaaa gtagagattt acatgtatag tagattgaaa ctagaatagt
    24541 acacctcaac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatt gatttctcct
    24601 gttcttgttt cattttacta tatttcttta aaaatgataa aggttgagat ttctcctcgt
    24661 aatagataat catggggata tttcaatcca aagttttatt cgttatcact tgactattgc
    24721 aaggttttct agagcaacag agtcatggaa tggactcatg gttgagattt ctccttgttg
    24781 cttggacttc attcaaaagt ctgttaccca agccttgttc aaacttccaa tacactagct
    24841 gtttccatag catgacttct gtactagact ttcttttccg aataaataga tagaaccaca
    24901 gaatctagta aacctagaat taaaattatg gtataatatt agcaataaaa gaaatctgga
    24961 ggattagaat catggtatca acgaaaacac aaattgctgg ttttgagttt gacaattgct
    25021 tgatgaatgc agcaggtgtg gcttgtatga cgatagagga gttagaagag gtcaaaaact
    25081 cagcggcagg aacctttgtt actaagacag cgaccttgga cttccgtcag gggaatcctg
    25141 agccacgcta ccaagatgtt ccacttggtt ccatcaactc tatgggcttg ccaaataatg
    25201 gcttagacta ttatttggat tatcttttag atttgcagga aaaagagtcg aaccgaactt
    25261 tcttcttatc tctggtcggc atgtctccag aggaaaccca tactattttg aaaaaagtcc
    25321 aagagagtga ttttcgtggt ctgactgagc taaatctttc ctgtccaaat gttccaggta
    25381 aacctcagat tgcctatgat tttgagacaa cagaccggat tttggcagaa gtgtttgctt
    25441 acttcaccaa acctcttgga attaaattgc caccttattt tgatattgtt cactttgatc
    25501 aagcggcagc tattttcaac aaatatccgc tcaagtttgt caactgcgtt aactctatcg
    25561 gaaacggcct ctatatagaa gacgaatctg tcgttattcg gcctaagaat ggttttggtg
    25621 gaattggtgg agaatacatc aaaccgactg ctctagccaa tgttcacgcc ttttatcaac
    25681 gtttaaatcc tcaaatccaa attatcggaa caggtggcgt tctgactggt cgagatgcct
    25741 ttgaacacat cctctgtgga gcaagtatgg tgcaggtggg aacgaccctt cacaaagaag
    25801 gtgtcagtgc ttttgaccgc attaccaatg aactgaaagc aatcatggtg gaaaaaggct
    25861 acgagagctt agaagatttc cgtgggaaat tgcgctatat tgactaaatt aaatcgaaaa
    25921 atctgaagaa aggagagacg atgctagcca ttgaagaaag tcagaagttg actttatcaa
    25981 atttaccgag cctgagccta tttacaggga cagatcaggg tcagtttgaa gtgatgaaga
    26041 gtcaagtgtt gaaacagatt gggtatgatt ctgctgacct caactttgcc tactttgata
    26101 tgaaagaagt agtttacaag gatgtggaac tggagttggt cagccttcct ttctttgcgg
    26161 atgagaaaat cgtgatatta gattatttta tggatatcac gactgctaag aaacgctttt
    26221 tgacagatga tgagcttaag tcatttgagg aataccttga caatccttct ccaacaacca
    26281 agttgataat ctttgcagaa ggaaagctgg atagcaaaag acggttagtc aaattactta
    26341 agcgtgatgc caaggtcttc gatgcagtag aagtaaaaga acaagaattg cgccagtatt
    26401 tccaaaagtg gagtcagaaa caaggtctgc agtttaccaa tcattctttt gaaaatctcc
    26461 tcatcaagtc ggggtttcaa tttagcgaaa tccagaaaaa tcttctcttt ttacagtcct
    26521 ataaggcgaa ttctgttatc gaggaagagg atattgttaa cgcaattccc aagaccttgc
    26581 aggacaatat ttttgattta actcagttta ttctgactaa aaagatggat caggcgcgcg
    26641 atttggtgag agacttgacc ttgcaagggg aagatgaaat caaactgatt gcagtcatgc
    26701 tgggacaatt tcggactttt actcaggtga agattttggc ggagtctggc caaacagaat
    26761 cgcagattgc aagtagttta ggtagttatc tgggacgtaa cccaaatcct tatcaaatca
    26821 agtttgcatt aagagattcg agaggacttt ctttgagctt tctgaagcaa gctatttcct
    26881 atttgattga gacagactat cagattaaga caggtcttta tgaaaaaggt ttcctttttg
    26941 aaaaggcact cttacagatt gctagtcagg tcaattgaca tttgttgaaa ctacaaccca
    27001 cgtcaggatt atcttgtcgt gggtttcttg ctgatttgct tattttatta gaaagtatgt
    27061 cagtgatttc cttatctata agcaaaaaac ttgaaaaaag tgaatgtttg cgttatcatt
    27121 ttcatataga aagaaaaaga ggtattacag atggctatta tcttaccaga acttccatat
    27181 gcatacgacg ctttggaacc atacatcgat gcggaaacaa tgcatttgca ccatgacaaa
    27241 caccatcaaa cttatgtcaa caatgccaat gcagctttag aaaaacaccc tgaaatcggt
    27301 gaagaccttg aagccttgct tgctgatgta gaatctatcc cagctgatat ccgtcaagca
    27361 cttatcaaca atggtggcgg acacttgaac cacgctcttt tctgggaatt gatgactccc
    27421 gagaaaacag ctccttcagc agaactgaca gcagcaatcg atgcaacatt tggttcattt
    27481 gaagaattcc aagcagcctt cactgcagca gcaacaactc gttttggttc aggttgggca
    27541 tggttggttg tcaacaaaga agggaaactt gaagtgactt caacagcaaa ccaagacaca
    27601 ccaatctcag aaggtaaaaa accaatcttg ggcttggacg tttgggaaca tgcttactac
    27661 gtgaaatacc gcaacgtgcg tcctgactat atcaaagctt tcttttcagt aatcaactgg
    27721 aataaagtag atgaattgta cgcagctgct aaataatgat agttggaggg aagaattgtt
    27781 cttctctttt ttaggttata agattctggt ctgacaaaat cgtcagactt ttttcatttt
    27841 tatgagaaac gtgctaactg ctagaaatta tggtagaata aagtattaag taatcgtgga
    27901 aaaaggatat ctatgcgaaa agaaattgca cctgaattat acaactataa caagtttcct
    27961 ggtccggagt tccatttaca cggggacaag gtcgaaacgg aagggatagc tttttccttg
    28021 gttgaaaata tcaaggatgc ctttgatgtg acgactttta atcagcgttt ttcagaagta
    28081 ttaaccaagt ttgattatat cgtgggggac tggagcaacg aacagcttcg cctacgaggt
    28141 ttttacaagg atgaccgaac agaagaaaaa cttgaaaaaa tcagtcgttt acaagactac
    28201 cttttagagt attgtagtta tggttgtgcc tattttgtct tagaaaatga agcccctaag
    28261 cgagcatcat ttgacaagaa aatgcgtaag acggaagaag aaacaccttc tagaaaagga
    28321 aagaaaccga ctcaaactaa acgaaagtcg aatgcagata agaaaaatag acgtcgtcag
    28381 aaagaccaac attctcagaa agaggacaag gaacaacgtc attttgtcat tcgtcagaag
    28441 tgagtagaga ataaggagaa gaaatgaaac cctcaattca tagtttggca catcaaacca
    28501 tgcaggaatg ggtattggag cagggagaaa agaaattccg tgcagatcaa atctgggaat
    28561 ggctctaccg taaacgtgtg cagtcatttg aagaaatgac caacctttcc aaggatttga
    28621 ttgctaagct caatgaccag tttgtggtca atcccttgaa acaacgtatt gtgcaagagt
    28681 ctgctgatgg tacagtcaaa tatctctttg aattgcccga cggtatgtta attgagactg
    28741 tactcatgcg tcaacactat ggtttatctg tctgtgtgac cactcaggtc agctgtaata
    28801 tcggttgtac cttctgtgcc tctggtttga ttaagaagca gcgtgacctc aataacggtg
    28861 aaatcgtagc gcaaatcatg ctggttcaga aatactttgc tgatgaaggg gttcaggtca
    28921 atcttgccgt gtctcttcac gcacccaaca atgaacttcg ttcaagtatc atgaaaatta
    28981 accgtgcctt tccgattgaa aaactctttg ctgctattga atactacatt gagacaacaa
    29041 accgtcgtgt aacctttgaa tatatcatgc ttaatgaagt caacgacggt gtagaacaag
    29101 ccttggaatt ggctgaattg ctcaagaaca tcaagaaatt gtcttatgta aacttgattc
    29161 cttataaccc agttagtgag catgaccaat atagccgtag tcccaaagag cgcgtgttgg
    29221 ctttctatga tacgcttaag aaaaaagggg gcaactgtgt ggttcgtcaa gagcatggta
    29281 cagatattga cgcagcttgt ggacaattgc gctttaacac aatgaaacgt gaccgccaga
    29341 aggcagtcgc agcggtaaat ccttaatgat gaagaagact tataatcata ttttggtctg
    29401 gggagtcatt ttctatagca tttgcattgt ctatttttgc tttactcctc aagaacaatc
    29461 taccgtggga gtgggaactc cagatattca gcctcttgga cgcctggttt ttcttttgac
    29521 tcctttcaat tctctctgga aactgggcga agtgagtgac attggacaat tatgttggat
    29581 ttttttacaa aatatcctca atgtcttctt gttttttcct ctgattttcc aactccttta
    29641 tctatttcca aatttgcgga aaacaaaaaa ggtccttctt tttagttttc ttgtgagtct
    29701 tggaatcgag tgtacgcaat taatcttgga ctttttcttt gattttaatc gcgtctttga
    29761 gattgatgat ttgtggacca acactttggg tggctatctg gcttggctcc tttataaacg
    29821 attacataaa aacaagataa ggaattaaaa tgagtatttt agaagttaaa aatctgagtc
    29881 acggttttgg tgaccgtgca atttttgaag atgtgtcctt ccgtctcctc aagggagaac
    29941 atatcggcct ggtcggtgcc aatggtgaag gaaaatcaac ctttatgagt atcgtgactg
    30001 gtaaaatgct gccagatgaa ggaaaggttg agtggtccaa atatgtgacg gctggttact
    30061 tggatcagca ctctgtcctt gctgaaagac agtcggtgcg tgatgttctc cgtacggctt
    30121 ttgatgagct tttcaaagct gaagctcgta tcaatgacct ctatatggaa atggctgaag
    30181 acggtgcgga tgttgatgct ctcatggaag aagtgggaga acttcaagac cgtctggaga
    30241 gtcgtgattt ctataccttg gatgctaaga ttgacgaagt agcgcgtgct cttggtatta
    30301 tggactttgg catggatacg gatgtaactt ctttgtcagg tgggcaaaga accaaggtgc
    30361 ttttggcaaa acttctcctt gaaaagcctg atattttgct gttggacgag ccgaccaact
    30421 acttggatgc tgagcatatt gattggctca agcgctatct ccaaaactat gagaatgcct
    30481 ttgtcctcat ttcgcacgat attccattcc tcaatgacgt tattaatatt gtctatcatg
    30541 tggaaaatca acagctgacg cgttactctg gtgactacta ccagttccaa gaagtttatg
    30601 ctatgaagaa atctcagcta gaggcagcct acgaacgcca gcagaaagag attgcagacc
    30661 tcaaggactt tgtggctcgt aataaagccc gtgttgcaac tcgtaatatg gctatgtctc
    30721 gtcaaaagaa attggataag atggatatta tcgaactcca aagtgagaaa ccaaaaccat
    30781 cctttgattt caaaccagct cgtacaccag ggcgctttat cttccaagcc aagaacttgc
    30841 aaattggtta cgaccgtcct cttactaagc ctttaaatct taccttcgaa cgcaatcaaa
    30901 aggttgcgat tattggtgct aatggtattg gaaaaacaac tctcttgaag agtctcttag
    30961 gcattatctc gccaatcgct ggggaagtgg agcgtggaga ttatttagaa cttggttatt
    31021 ttgagcagga agtagaaggc ggtaatcgcc aaactcctct tgaagctgtc tggaatgcct
    31081 ttcctgccct taatcaagca gaagtccgtg cagcccttgc ccgttgtggt ttgacaacca
    31141 aacatattga aagccagatt caagtattat cagggggaga gcaagccaag gttcgtttct
    31201 gtctcttgat gaatcgtgaa aacaacgttt tagtgctgga cgagccgacc aaccatttgg
    31261 atgtggatgc aaaggatgag ctcaaacgcg ctctcaaaga atatagggga tctatcctta
    31321 tggtctgcca cgagccagac ttttatgaag gctggataga ccaaatatgg gattttaata
    31381 atttaactta agaatgagag taaaagaaat acagtaccga atgtggatac tgtatttttt
    31441 tggtttttaa gatttaaaat cgtagtcttt caccacttcg atgctgtcga ttgtgatagc
    31501 agtagttggc ttgtcttttt catctttttc ggccttagca atcttatcca caacatccat
    31561 accgtcaatc acttgaccaa agactgggtg tttgccatct agactagggt ttccaccttc
    31621 tttgtaggct tcgataattt tctgtggata cttgcttgta gggagtttag aagaggtatc
    31681 tgtagagttt tggttgatga agaactggct gccattggtg tttggttgac cagtattagc
    31741 catagcaaga gcaccacgga tgttatacaa ataaggagta atctcgttct tgaaaccagt
    31801 tcctttgtct ttagtcttat ccttgtcatg ccagatggac tgaccacctg taccgtcccc
    31861 ttttggatct ccagtttgga ccataaagcc atcgatgaca cggtggaagg taataccgtt
    31921 atagtagcct tctttggcgt gagtgaggaa attttcaacc gctagaggag cgagtttagg
    31981 gaagagttta atgcgaatat caccttggct tgtgtggaga atcacttcgg cttcatcttc
    32041 agcaacttcc ttagatagtt gtgggaaatt ggcgttttcg tttgttaaag catcgtttaa
    32101 ctccttggca gattgggcag ctactttgga actttcttca gcagcaagac tggaatcaac
    32161 ataatcatca ccacgcagac tgcgttggac gctgctacac ccagctaggg ctacagtaga
    32221 cagtaaaaga agggttgcta gttttttcat tctgatcctc tcaaaaattc atttataacc
    32281 attgtaccct aaaaggaagt ggatttcaaa tattagtagt ttacagaact ggcttagata
    32341 atagttggga tttcatcatc atcttgaaaa tcttcaactt cttccccagt aaatggtttc
    32401 tgaaaagaac ttagtataaa acgggcaatt ggttcaacaa ttaggaaatt tagaggaaga
    32461 gctgcaataa agtttacgaa ccaggcgctt agataggtat tgggtgtgat agcaatgcca
    32521 ttgtaaaaaa agtccataga aggacatgaa agtgaccagc taattcttct tctgaaaaat
    32581 gctcatgaag ggcttgatcc aggtcgcaag atttcatttt agaaagtcca gtaactccct
    32641 tcttcttcag gatattcttt ttcatggtag tatttagatg gtcaagtgag tcaaaagaag
    32701 tttcgacaag agcataccct ttttctacca gagtttttag atgtttaggg gcatcaatac
    32761 cataagtgta ctcaaagtat tttggaaacc agatcttaag aaagctcgta aagctagcca
    32821 gttctctaaa cgctaagaac tagctacaac acagcattta caacacttca tggttcacac
    32881 catggggtgt tttttaatga ttttaagcaa aattcacact taattgaaag ttatttaaat
    32941 tagatgaaaa tttatttttt gaaaaagtgg gaaaacattg attctaagcg aattttgaat
    33001 catattcgaa tgggagtttt taaaatcatg tttcagtggt aaaagtacca aactggattc
    33061 tccatagtaa aatgatatct cctgctagtg aatcatctac taataagtcc atatttcgct
    33121 tgggaacggg cttgggactt agaagccaag tatccaactc tcgttcaggc gatatgaagg
    33181 gtttgacttg gtgttcttta taaaattttt ctaaaatagt attcacggat agcatctttc
    33241 aaacatttat ttcctattct aacaaatttc taaatacttt aagaaattta tagtctgtca
    33301 agtttttttc ttgacacatg tcagaaatct gctataatag aacatgtgct aaatagctca
    33361 gctatttcac cgaaataaaa aattaaagaa atgagacttt aaaaatggca gttaaaatcc
    33421 gtttgactcg tatgggttct aagaaaaaac ctttctaccg tatcaacgta gcagattcac
    33481 gttcaccacg tgacggacgt ttcatcgaaa cagttggaac ttacaaccca cttgttgctg
    33541 aaaaccaagt aactttgaaa gaagaccgcg ttcttgcatg gttggctaat ggagctcaac
    33601 cttcagacac agtacgtaac atcctttcaa aagaaggcgt attgaaaaaa ttccacgatt
    33661 ctaaattttc aaaataagtt taaagtaggt tgacagatgg atacgattga aaatctcatt
    33721 attgcgattg tgaaaccctt aatttcacaa ccagatgcct taactatcaa gattgaggat
    33781 acaccagaat ttttggaata tcatttgaat cttgatcaaa gcgatgtggg tcgtgtaatc
    33841 ggtcgtaagg gtcgcactat ttctgcgata agaacgattg tctactctgt cccaactgaa
    33901 tacaaaaaag taagaatcgt tattgacgaa aaataagaag ggcgggacgg atgtctcgct
    33961 tttttgtgtg gaatagaaga tatagtaaaa tgaaacaaga acaggacaaa tcgatcagga
    34021 cagtcaaatc gatttctaac aatgttttag aagtaaaggt gtactattct agtttcaata
    34081 tactataaaa gattgaacgt ttaggcaatt ccaagactac ttaatcgaac attaacagca
    34141 gtctcggact gatgaaggtc tctttatgaa gttagtggag gaagtcggaa aagtagccga
    34201 ggttttgaat aggcgctctg gtcgaaaaga agggatagga ttcgaacgag gaacttgcca
    34261 gagaactggc tgatatcatt tactacaccg tcgcaatcgt agctattaat catattgacc
    34321 ttaccaagac tgtctttgag aaagacaaaa ccgcagccgt taattaccaa cataaacata
    34381 atttggaagg attattgaag ggaaagtaga gatgttgtcc ccttcctcca acttgagaaa
    34441 atccttggaa cgtgataaaa taaaggataa tgatttttaa taattcatta tatagaatga
    34501 gtggatttct ttatgaagag gtttgaagta tctacagaaa ttggtagcct ctctgttact
    34561 tatcaaaagc aaaagaaagt gctagtttgt ctaaacggag caggtttgct accaagttat
    34621 gaaaattttt cacttatact tgaaaaacct cctcctacaa ttggttattt gacaattgat
    34681 tttccgaaca caggtaggag tccgattcat gaccaagctg gaaaaaatct agataatctt
    34741 gcagatgcgg tttatgaagt acttgaagaa ttaggaattt ctgaatatat actttgtgca
    34801 catagttgga gtggaatttt agcttgcaaa ttactcgaga aaccaattaa gcgtcagact
    34861 ttagtagcaa ttgaaccgac aactaaaaaa gtcatgtttg ctgatttttc agaaaatcct
    34921 tatccaaaaa tggaagagca gatgaggctg attgacgagt gtggtcctga actttatttt
    34981 aagaacttaa ctcaagcaac atttagtcct gaaacgaata aaaaaatctg ggaattaatg
    35041 caagaaaaag gcttagagtt ggaaaatcaa gatccagaat ttcagatatc tggagagatt
    35101 actgaggaag attttgagaa tttgtcgata gaatctcatg tccctgtttt tattttttgt
    35161 cagacttata gagaaaaaga gtacagagaa tcagaatatt ggacttccaa tactaaactc
    35221 attttaggag ggaatcacca ttatttacaa tggtcagaat cggaaaaaat tgcggctatt
    35281 attcgagaat tgtcagaata agatggaaaa aaggagatta caggagacaa gatgaactac
    35341 tttaatattg ggaaaatcgt taatacgcag ggattacagg gtgagatgcg agtcttgtct
    35401 gtgacggatt ttgcagaaga acggtttaaa aaaggagctg agctggcttt gtttgatgaa
    35461 aaagatcagt ttgtccaaac agtgaccatc gctagccacc gtaaacagaa gaactttgac
    35521 attattaaat tcaaagatat gtaccatatc aatactatcg aaaagtacaa gggatacagt
    35581 ctcaaggtcg ctgaggaaga tttgaatgac ctagacgatg gtgaatttta ctatcacgag
    35641 attatcggtt tggaagtcta tgagggtgat agcttggttg gaaccatcaa ggaaatcctg
    35701 caaccaggtg ctaatgatgt ctgggtggtc aaacgaaaag gcaaacgtga tttgctttta
    35761 ccttatatcc caccagtggt tctcaatgtt gatattccaa ataaacgggt cgatgtggaa
    35821 atcttagaag ggttagacga tgaagattga tattttaacc ctctttccag agatgttttc
    35881 tccactggag cactcaatcg ttggaaaggc tcgagaaaaa gggctcttgg atatccagta
    35941 tcataatttt cgagaaaatg ctgaaaaggc ccgtcatgta gatgatgatc cctacggagg
    36001 cggtcagggc atgttgctca gagcacaacc tattttcgat tcctttgatg ctattgaaaa
    36061 gaaaaatccg cgcgttattc tccttgatcc tgctggaaag cagtttgatc aggcttatgc
    36121 tgaagatttg gctcaagagg aagagctaat ctttatctgt gggcactatg agggttatga
    36181 tgagcgcatt aagaccttgg taacagatga gatttcccta ggcgactatg tcctcactgg
    36241 tggagaattg gcagctatga ccatgattga tgctacagtt cgcctgattc cagaagtgat
    36301 tggcaaggag tctagccacc aagatgatag tttttcttca ggtcttttag aatatcctca
    36361 gtacacacgt ccctatgatt atcgaggcat ggtcgtgcca gatgtattga tgagtggcca
    36421 ccatgaaaag attcgtcagt ggcgattgta cgagagttta aagaaaacct acgagcgcag
    36481 accggattta cttgaacatt atcaactgac agtagaagaa gaaaaaatgc tggcagaaat
    36541 caaagaaaac aaagaataaa ggagaaacct atgcaagtaa tcaaacgtaa tggcgaaatt
    36601 gctgaattta atccagataa gatttaccaa gccatcttga aggcagccca aactgtttat
    36661 gttttgacag atgatttgcg tcaaaatctt gctcaagtca ctaagaaggt agttttggat
    36721 ttacaagaag ccaaggtgga acgtgcgact atcagtatga ttcaatctat ggttgaacat
    36781 cgtttattgg gcgcaggtta cattaccatt gcagaacact acatttccta tcgtttacaa
    36841 cgtgacttgg aaagaagtgg ttatggagat catatcgcag ttcatttaca ttttgaacaa
    36901 attcgctaag aaaaaagagt gggatgaagc aactacatct cactctttct taaatctatt
    36961 ttttttggct gtttggacag ttgaggggac aaatcgcagg cgttgaatat cgcttatacg
    37021 gataatccgg ctcacatttt tggcaaaatt tttcacgata atttgctggc cttgctgatc
    37081 atatttgatg atatcacctg taaagcttgt ctcagacaag ataaggtgaa cagcggtttg
    37141 tttctggata gcctcttcaa tagtggctgt aagggagttg gtttcagtct ggtcaggttg
    37201 gtcatgtcca tttaaaaaat catgtatttt atctagaact tgctggaatt tatgtctcat
    37261 attggcctcc cttcttctat atcaatatta tataaaattt tcctaaaatc tacaagattt
    37321 tacgaataaa ctaatgaaac taaaaaagga gaagaaaatg gcagaattta catttgaaat
    37381 cgaagagcac ttgttgactc tttctgaaaa cgaaaaaggt tggaccaagg aaattaaccg
    37441 tgtgagcttt aatggtgccc ctgcaaagtt tgatattcgt gcttggagtc cagaccatac
    37501 taaaatgggc aaagggatta ctctctcaaa tgaagaattt caaacgatgg tggatgcctt
    37561 taaaggcaac taatactctt cgaaaatctc ttcaaaccgc atcagctttg ccttgccgta
    37621 tgtatggtta ctgacttcgt cagtttcatc cacaacctca aaacagtgtt ttgagcagcc
    37681 tgcggctagc ttcctagttt gctctttgat tttcattgag tataagtttt caaaataaaa
    37741 aaaaaggata ttgagtcatg ataactcgat atcctttttt agttagtaaa gtaagcctga
    37801 tttttaaggc gttgaagtag gggacggcta ataaaactaa tagccagaag tttgccaagg
    37861 tctggaatga taaagggaag aacccccaca acaagagctt tttcaaatgc cattccagct
    37921 aggaaatgca agctgagaat cccgccgaca aagacaaggg catcacccaa gaggtttgca
    37981 agaaaaatct taacaacacc actcttgctg ttggttagag aggaagtaag tccagagtaa
    38041 acgagataaa accaaagata gcctgcagta gggccaacta aagcctgaaa accagctcca
    38101 cctcctgcaa agacaggaag accgatagca cctagaagaa gatagagtcc agcagaaagt
    38161 acagcctctc tcggtctaaa gacagtagca atcaagccga ttgcaaagtt ttgcagagtg
    38221 aagggaacag gtccaattgg aagactgatt tgtgccaaaa cagcaatgag agcagcccca
    38281 atagcaggga tagcataaac gtgagctttt ttcaaaatag ttaacctctt ttctaatgta
    38341 tagtaactat tatactcata taggagtcga tgtcaaccat tttttaaaaa caaggtaaca
    38401 aaaactgtaa cagccgattt tcgtgactag tcaagttgga taattttttt gttgatt
//
LOCUS       DAVKBK010000017        37904 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVKBK010000017 DAVKBK010000000
VERSION     DAVKBK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.017"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            147..281
                     /gene="rpmH"
                     /locus_tag="VWX69_000913"
     CDS             147..281
                     /gene="rpmH"
                     /locus_tag="VWX69_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU9192279.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            565..1458
                     /locus_tag="VWX69_000914"
     CDS             565..1458
                     /locus_tag="VWX69_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU9192280.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATLEY
                     KLETIPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            1763..2536
                     /locus_tag="VWX69_000915"
     CDS             1763..2536
                     /locus_tag="VWX69_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU9192281.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            2536..3096
                     /gene="rnmV"
                     /locus_tag="VWX69_000916"
     CDS             2536..3096
                     /gene="rnmV"
                     /locus_tag="VWX69_000916"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU9192282.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            3168..4067
                     /locus_tag="VWX69_000917"
     CDS             3168..4067
                     /locus_tag="VWX69_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9192283.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            4387..4683
                     /locus_tag="VWX69_000918"
     CDS             4387..4683
                     /locus_tag="VWX69_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9192284.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            4760..6790
                     /locus_tag="VWX69_000919"
     CDS             4760..6790
                     /locus_tag="VWX69_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9192285.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     LGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            6792..7433
                     /locus_tag="VWX69_000920"
     CDS             6792..7433
                     /locus_tag="VWX69_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192286.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            7426..7719
                     /locus_tag="VWX69_000921"
     CDS             7426..7719
                     /locus_tag="VWX69_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192287.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            7970..8842
                     /gene="rsmA"
                     /locus_tag="VWX69_000922"
     CDS             7970..8842
                     /gene="rsmA"
                     /locus_tag="VWX69_000922"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU9192288.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLMPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            8844..9722
                     /gene="rsgA"
                     /locus_tag="VWX69_000923"
     CDS             8844..9722
                     /gene="rsgA"
                     /locus_tag="VWX69_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU9192289.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            9733..10389
                     /locus_tag="VWX69_000924"
     CDS             9733..10389
                     /locus_tag="VWX69_000924"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU9192290.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            10352..11014
                     /locus_tag="VWX69_000925"
     CDS             10352..11014
                     /locus_tag="VWX69_000925"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU9192291.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            11016..12272
                     /locus_tag="VWX69_000926"
     CDS             11016..12272
                     /locus_tag="VWX69_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU9192292.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            12262..13203
                     /locus_tag="VWX69_000927"
     CDS             12262..13203
                     /locus_tag="VWX69_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU9192293.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            13470..14297
                     /gene="purR"
                     /locus_tag="VWX69_000928"
     CDS             13470..14297
                     /gene="purR"
                     /locus_tag="VWX69_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU9192294.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            14364..15614
                     /locus_tag="VWX69_000929"
     CDS             14364..15614
                     /locus_tag="VWX69_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU9192295.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            15740..16534
                     /gene="pflA"
                     /locus_tag="VWX69_000930"
     CDS             15740..16534
                     /gene="pflA"
                     /locus_tag="VWX69_000930"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU9192296.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(16609..17535)
                     /gene="yidC"
                     /locus_tag="VWX69_000931"
     CDS             complement(16609..17535)
                     /gene="yidC"
                     /locus_tag="VWX69_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9192297.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(17613..17891)
                     /locus_tag="VWX69_000932"
     CDS             complement(17613..17891)
                     /locus_tag="VWX69_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU9192298.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            17925..18665
                     /locus_tag="VWX69_000933"
     CDS             17925..18665
                     /locus_tag="VWX69_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU9192299.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            18721..19404
                     /locus_tag="VWX69_000934"
     CDS             18721..19404
                     /locus_tag="VWX69_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU9192300.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            19517..20509
                     /locus_tag="VWX69_000935"
     CDS             19517..20509
                     /locus_tag="VWX69_000935"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU9192301.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            20574..21113
                     /gene="rsmD"
                     /locus_tag="VWX69_000936"
     CDS             20574..21113
                     /gene="rsmD"
                     /locus_tag="VWX69_000936"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU9192302.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            21103..21591
                     /gene="coaD"
                     /locus_tag="VWX69_000937"
     CDS             21103..21591
                     /gene="coaD"
                     /locus_tag="VWX69_000937"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU9192303.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGRDIACYVPESILEEIRNEK
                     KD"
     gene            21575..22612
                     /locus_tag="VWX69_000938"
     CDS             21575..22612
                     /locus_tag="VWX69_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU9192304.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            22670..22900
                     /locus_tag="VWX69_000939"
     CDS             22670..22900
                     /locus_tag="VWX69_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU9192305.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            22924..24207
                     /gene="murA"
                     /locus_tag="VWX69_000940"
     CDS             22924..24207
                     /gene="murA"
                     /locus_tag="VWX69_000940"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9192306.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            24200..24388
                     /locus_tag="VWX69_000941"
     CDS             24200..24388
                     /locus_tag="VWX69_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9192307.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            24427..25251
                     /gene="endA"
                     /locus_tag="VWX69_000942"
     CDS             24427..25251
                     /gene="endA"
                     /locus_tag="VWX69_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU9192308.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            25480..26811
                     /locus_tag="VWX69_000943"
     CDS             25480..26811
                     /locus_tag="VWX69_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU9192309.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRIAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(27009..27079)
                     /locus_tag="VWX69_000944"
     tRNA            complement(27009..27079)
                     /locus_tag="VWX69_000944"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27045..27047),aa:Cys,seq:gca)
     gene            27495..31106
                     /gene="rpoB"
                     /locus_tag="VWX69_000945"
     CDS             27495..31106
                     /gene="rpoB"
                     /locus_tag="VWX69_000945"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9192310.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            31139..34816
                     /gene="rpoC"
                     /locus_tag="VWX69_000946"
     CDS             31139..34816
                     /gene="rpoC"
                     /locus_tag="VWX69_000946"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU9192311.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            34927..35340
                     /gene="ndk"
                     /locus_tag="VWX69_000947"
     CDS             34927..35340
                     /gene="ndk"
                     /locus_tag="VWX69_000947"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU9192312.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(36269..36901)
                     /locus_tag="VWX69_000948"
     CDS             complement(36269..36901)
                     /locus_tag="VWX69_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192313.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(36903..37670)
                     /locus_tag="VWX69_000949"
     CDS             complement(36903..37670)
                     /locus_tag="VWX69_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9192314.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
BASE COUNT        11171 a         7272 c         8720 g        10741 t
ORIGIN      
        1 agggcttgca ttcgaaaaag ctggaaacat ttgcctagag ctattgacaa aagtgaaaga
       61 atcagataga atagtaaagt atgtttagta actgatcact ttatagccgg ctaaacgaat
      121 acaaaatcta tgaggaggta ttcatcgtga aacgtactta tcaaccaagt aaacttcgtc
      181 gtgcgcgtaa acacggattc cgtaaccgta tgtcaactaa aaatggtcgt cgcgtattgg
      241 cagctcgtcg tcgtaaagga cgcaaagttt tggctgcata atccaaacga attctatcaa
      301 aaatcagtag gaactcgagt ctactgattt ttatttttgt aaaaaagttc agtagatgca
      361 aatggattcg gaagcgatgt tatagtagat tgaaactaga atagtacacc tctgtttcta
      421 aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcctgttat tattttattt
      481 tactataaag ttgaagtagg tggagatggt acagcaacaa tcgtctttaa agatggttca
      541 gctattacaa ttccaggaaa tcaattggta gcacaagatc caaaagcaca agatagcact
      601 aaaccgactg ctgaaaaatc aactgttaaa gcacctgctc aaagagtaga tgtaaaagat
      661 ataactcatt taacagatga agaaaaagtt aaggttgcta ttttacaagc aaatggttca
      721 gcattagacg gagcgacaat caatgtagct ggagatggta cagcaacaat cacattccca
      781 gatggttcag tagtgacgat tctaggaaaa gatacagttc aacaatctgc gaaaggtgaa
      841 tctgtaactc aagaagctac actagagtat aagctagaaa ctataccagg tggagataag
      901 ggaggcaata ctggaagctc agatgctaat gcgaatgaag gcggtggtag ccaggcgggt
      961 ggatcagctc acacaggttc acaaaactca gctcaatcac aagcttctaa gcaattagct
     1021 actgaaaaag aatcagctaa aaatgccatt gaaaaagcag ccaaggataa gcaggatgaa
     1081 atcaaaggcg caccgctttc tgataaagaa aaagcagaac ttttagcaag agtggaagca
     1141 gaaaaacaag cagctctcaa agagattgaa aatgcgaaaa ctatggaaga tgtgaaggaa
     1201 gcagaaacga ttggagtgca agccattgcc atggttacag ttcctaagag accagtggct
     1261 cctaatgctg ctcctaagac aacaagtgca ccgcaagcaa ctgcaggaac aatgcaagat
     1321 gttacctacc agtcacctgc tggcaaacaa ttacctaaca caggttcagc atcaagtgca
     1381 gcacttgcta gtcttggtct agtggtggca acaagtggtt ttgctttgct aggaagaaag
     1441 actagacgta gaaaatagaa cagctagaaa attctattct ctacttaaag ttagattata
     1501 agggggattt tgagaagtca tcaatcctag tgatgggtga gaaaagtgag aacccaagat
     1561 aatcacatac tttagctgaa taggaatatt ctatcaatgt agccaatctc ttctgtctct
     1621 aactgtggaa taggagatgg gcaatatcgg atagaaaaga tagcagaata gctctctatt
     1681 gaagagagga ggggaaaccg aaaaattagg tgcccctcct cttttttggt ataatagaag
     1741 atagaaaacg aggttagaag agatgatttt tgatacacat acacacttga atgtagaaga
     1801 atttgcaggt cgtgaggcag aagaaattgc cttggctgct gagatgggtg tgatacagat
     1861 gaatattgtt ggttttgata aaccgacgat tgagcgtgcc ttggagttgg tagatgagta
     1921 tgagcagctc tatgcgacta ttggttggca tcctacagaa gctggtactt atacagagga
     1981 agttgaggct tacttgttgg ataagttaaa acattccaag gttgtggctt taggtgaaat
     2041 tggcttagac taccattgga tgacagcgcc caaagaggtg caggagcagg tttttcgccg
     2101 tcagattcag ctatctaagg acttggattt gccttttgtt gtccataccc gtgatgcgct
     2161 ggaagatacc tatgagatta tcaagagtga gggcgttggt cctcgtggtg gtatcatgca
     2221 ttcattttca gggacgcttg agtgggcaga gaagtttgtg gatcttggta tgaccatttc
     2281 cttctcagga gtggtgactt tcaagaaggc aactgacctc caagaagcag ctaaagagtt
     2341 acctttggac aagatgttgg tggaaacaga tgcgccttac ttagcacctg tacccaagcg
     2401 tggtcgtgaa aataaaacag cctatactcg ctatgtggtc gactttatcg ctgacttgcg
     2461 tggtatgacg acagaagagc tggcggtagc aacgactgca aatgcagaac gaatttttgg
     2521 attggacagc aagtaatgaa agagaaaatt tctcaagtta tcgtggttga aggtcgctat
     2581 gatacggtca atctcaagcg ttatttcgat gtggagacct atgagacacg aggttctgcc
     2641 atcaatgatc aggatataga gcgaattcag cgtctacacc aacgtcatgg agtcattgtc
     2701 tttacagacc cagattttaa tggggagcgg attcggcgca tgattatgac ggccattcca
     2761 acagttcagc atgcctttct caagcgagat gaagctgttc ccaagtccaa gaccaagggg
     2821 cgttctctgg gaattgagca tgccagctat gaagacctga aaacggctct agctcaggtg
     2881 acagaacaat ttgaacatga gagtcagttt gacattagtc gtagcgactt gattcgcctt
     2941 ggttttctag caggggcaga cagccgtaag cgtagagaat atctcggaga gactctccga
     3001 atcggctatt ctaatggcaa gcaactcctc aaacgcctag agttgtttgg ggttactttg
     3061 gcagaagtgg aagaagctat gaaatcttat gagtaggaaa gatgtagccg ttacaatttt
     3121 ttaagtttca cagtattttt cgaagcaggt agaagaggag gcgtctgatg ttaattggtc
     3181 aaaaaattaa agagattcgg atagaaaaag gaattagtcg tccagatttt tgtggagatg
     3241 agcaagaact gacagttcgt caactgtcgc gaattgaaag tggagcttcg caaccgagtt
     3301 tgcccaagtt agcctatatt gctcgccggc taggagttcc agtttatagc cttatgccgg
     3361 atttttcagc tcttccttct gcttatttag aattgaaata ccagatttta cgtgaaccaa
     3421 tctatggtaa agaagaggag tatgataaga aagaagcgtg tttggaagag atttataaaa
     3481 catactttga taatcttcct aaagaagaac aattagcatg tgaagtattg caggcgtgtt
     3541 tggatacttc tagaactaga aggcctgaat atgcagagtt aatacttgag gaacatatgt
     3601 ctcagatcat agaaaaagaa gtttattcaa caaatgatat gttgttgatt cgtttgtttt
     3661 tttatcaaat gctcattaga aaagatcttg ccaaatttat aaatcaaatc gaaaagctaa
     3721 tgctctttct tttggaacag aaaaaggtaa ctaaattaga aaacttcttt ataattagag
     3781 atactcttat ttcaggaatg tgttgtcttg aaaaggtagg agtaactgat tgttttaatg
     3841 attatctatc gtgtttacaa gaaattatgg ataaaactca agattatcaa aagaaacctc
     3901 ttgtatttat gtttttgtgg aagcaagcat taagagtaga aagagatttt agtttagctg
     3961 aatcatttta tcagtcttct aaaacatttg cgaagctaat tggagatgga tttctagtaa
     4021 agaaattgac agaggaatgg caagaggatg tcaaaaaata tttataaaca tagtgaatca
     4081 gtgacaaaaa tgtccttgtc ctcgtatcaa aacagttcta aagttcgtct ttagaactgt
     4141 ttttttagat ataagctaaa aataatatga aatagttaga ttttaaggac attgatgtcc
     4201 ttgatagtgt gataaagatg gagtataatg actataaaag ttcatttcag ggtgctattt
     4261 tgacaattta gagaaaaaca aataatttta gaatatcatt tggtaatata atagtatcaa
     4321 cgttgataat ggaaagagga gcaagtaact caacaatctt gtaatcaaaa atagaggagt
     4381 atcaatatga aacaaacagt taaaaagtta gctcttgtag cgagcattgc agcaacatta
     4441 ggtggaggtg tatcagttgc ctctgcagcc gttcaatacc cagaaggtgg tgtttggact
     4501 tatggttcag gtaacggtgg tgcttactca aactactatc acccttcaaa ataccatagt
     4561 tcaacagttg ttagcagaaa aactggttca tctgacaagg gatatgctgg tgctggaggg
     4621 acttctcgtg catggattcg tacttcttgg ggagagaaag ttgcattcta ctataatgtt
     4681 tagaatggta tagccctatt gtttagcttt acttggtcac cttctcacta agtgaccaag
     4741 taactttttg gaggaaatga tgaaacgttt atttattttg atttcaatgg tattggtatc
     4801 gctttatatg gtgataactt ccgttgacca tcgagaagag attttatttg gtaactatcc
     4861 ttctgttgat gtgacaggaa tgatgataaa tcaaccagta gctagtcgcg aagaggtgac
     4921 agaggctttg agtcacttgg cggtagagca taatagtctc atcgcccgtc gaatcgttga
     4981 gccaaatgaa gctggagaaa cactctttac ctatgccact tatggtgagg gagagcttcc
     5041 agaaggtctg accatttcct ccaaggagag tgcagaaacg agtgatttat tagggtctta
     5101 cttgattgtg tcaggaagtt tggatggagt gagcttacag accaccttga aagagcttgg
     5161 ttatcaaggc tttgtttcga atggagaaga tccattttcg atagtcttac tattggcggc
     5221 cacccctatg gtgctactga gtttagctat ttttctgctg acctttatga gtctgaccct
     5281 gatttatcgg atcaaatccc ttcgtcaggc agggattcgc ttaatagctg gtgagagctt
     5341 gtttggagtt gctctcagac cagtgttaga agatgtgaga cagcttatct gctcagtgct
     5401 ggtatccagt cttttgggat tggggattct ctggtatcaa ggtgccttgt ttatggcaac
     5461 ggtacaactg gtcatcattg ctcttctact ttatggattg accttggcag ggatttctac
     5521 cttactaagt gtcgtctatc tacttggttt acaggaaaat agtctggtgg atctattgaa
     5581 agggaaactc cctctcaaac gtatgatgac attgatgatg gtggggcaac tcttagctgt
     5641 attggtggtc ggatcgagtg cgacagctct cctaccccac taccgtgaaa tgcaggaaat
     5701 ggagagagct agcaataaat ggagccagtc ctcagaccgt taccgtctat cctttggttg
     5761 gtctagtgca tttgccgatg aagaaggaac gcgtaaggat aatcgtgagt ggcagacatt
     5821 tactgaagaa cggttagcca atacagactc tttttatatt atgagcaatg ttgacaattt
     5881 ctcagatgga gcagaagtgg acctagatgg caatcgtctc agtgactaca caccgttagg
     5941 gaatgttatc tatgtctcgc cgcgctatct gatagaagaa aagattaccg tttcttcaga
     6001 gtttatggac aagatgcaaa acttgtctga gggagagttt gggctgatct tgcctgagag
     6061 cttgcgagag cagtctgcct actaccaagg attgtttaca gattacctgc aaaacttttc
     6121 atctgaaagt gtagaagtga cgagtcagaa acactacctc ccacaggtaa ggctagcttt
     6181 tacagaaaca ggacaggaac gtttcctcta taatgatggg tacaagacaa cacgccagta
     6241 cctaaaagat ccgattattg tagttctaac gccgcaagcg actggaacaa gacctgttgc
     6301 agggatgttg tggggaacta cggctaatag tgccttgaaa ctagatcgat atggagacag
     6361 catcacagct ctaaaagagc aaggtctgta tcacaaggtt tcttacttgg taaaaagcca
     6421 gctatttttt gccaaggtac taaatgacaa acgggtggag ttttactctc tccttattgg
     6481 gacgattttg accctgtcta cggctatctt gttatttgat tccatgaatc ttctctattt
     6541 tgagcagttc agacgggaac ttatgattaa acgtcttgct ggtatgacaa tctatgagct
     6601 tcatggcaag tatttactgg cgcaaggagg agttctcttg cttggcctag tcctatctag
     6661 tattttgaca agagatggtt tgattagcgc tctagttgta gctttgttta cgcttaacgc
     6721 cctcttgatt ttagtaaggc aggataaaaa agaagaagct ggtagcatgg cagtattgaa
     6781 aggaaaataa gatgattgat attcaaggat tggaaaagaa atttaatgac cgcgcgattt
     6841 tctctggttt gaatctcaag ctggagaagg gcaaggttta tgccttaatc ggaaagagtg
     6901 gaagcggaaa gacgacgctg ctgaatatct tgggaaagct agaaaagata gatggtggaa
     6961 gggttctcta tcaggggaaa gatttaaaaa ccattcctac tcgtgagtat tttcgagacc
     7021 agatgggcta tctctttcaa aatttcggcc tcttagaaaa ccaatcaatc aaagaaaatt
     7081 tggatttggg ttttgttggt cagaaaatct caaaagtaga acgtttggaa aggcaagtgg
     7141 gggctttaga aaaagttaat ctagggtatt tggatttaga acaaaaaatt tatactttat
     7201 ctgggggaga ggcccaacga gttgcccttg ctaagactat tttgaaaaat ccacccttga
     7261 ttttggcaga tgaaccaaca gcagctcttg atcctgaaaa ttcagaggag gttatgaatc
     7321 tcttggtgga tttgaaagat gaaaatcgaa ttatcatcat tgcgacccat aatcccctag
     7381 tctggaataa ggctgatgaa atcattgata tgaggaaact tgctcatgtg tgaaaaaatc
     7441 cgtattcgca gggtatctga ttatcctagt gccagaggtg gtttagaaga tatcctcatc
     7501 atggaaaata tgaccaatca tctccttttg gttcaaatcc gagtgcatgg ctatttgctt
     7561 gattttgcta gtattgaagg gcaaaggcaa aagcattatc gtttgaaaaa tttacctcag
     7621 acggttgaac tgacagtgga tgatgtggag gaggatgtgg atttgaccct acccgaaaat
     7681 cgaagttatc aagaagctga tttttttgat actcaatgaa aatcaaagag caaactagga
     7741 agctagccgc aggctgtact tgagtacggc aaggtgaagc tgacgtggtt tgaagagatt
     7801 ttcgaagagt atgaacgtat gtttcgagag aagcactaag tccctcttta aagatttcca
     7861 agactatctt tcttcatgag gaaagatagt tttttggtat gattttcatt cccaaaatac
     7921 aaggggaatg tgttacaata gtagtaacag ataatagaaa agagaataga tgagaattgc
     7981 agattatagc gtgaccaagg cagtgttgga gcgtcacggt tttaccttta aaaagtcctt
     8041 tgggcaaaat ttcttgacgg ataccaatat ccttcaaaaa attgtggata cggctgaaat
     8101 tgatgatcag gtcaatgtca tcgaaatcgg gccaggtatt ggtgccttga cagaattttt
     8161 ggctgagcgt gcagcccaag tcatggcttt tgagattgac caccgtttga tgccaatttt
     8221 ggcagatact ctgcgtgatt ttgataatgt gaccgtagtt aacgaagata ttctcaaggt
     8281 tgatttggcg caacatatcc aaaattttaa aaatcctaac ctgccaatca aggtagtggc
     8341 taatttgcct tactacatca cgacgcctat tctcatgcac ttgattgaga gtggcattcc
     8401 tttttgtgag tttgtggtca tgatgcagaa agaagtagcg gaccgcattt cagcccagcc
     8461 taacaccaag gcttacggta gcttgtctat cgccgtgcag tattacatga cagccaaggt
     8521 tgcctttatc gtgcctcgta cggtctttgt gccagcgcca aatgtggatt cagccatctt
     8581 gaaaatggtg cgtcgtccag agccagccgt agcagtagaa gatgagaact ttttctttaa
     8641 ggtttccaag gctagtttta cccatcgccg caagaccttg tggaataact tgacaggtta
     8701 ctttggtaag actgaagagg tcaaggacaa gctgaccaag gctttggacc aggcaggctt
     8761 gtcaccaagt gtgcgtgggg aagctctcag cttggcagaa tttgccggtc tagcagacgc
     8821 acttaaaggg caaggactct aagatgcagg gacaaatcat taaagccttg gcaggtttct
     8881 actatgtgga gagtgatggc caggtttatc aaacacgcgc gcgtgggaat ttccgtaaaa
     8941 aaggccatac cccttatgtt ggggactggg tagatttctc tgccgaggaa aattcagaag
     9001 gctatatcct caaaattcac gaacggaaaa acagtctggt tcgtccgcct attgtcaata
     9061 tcgatcaagc tgtagtaatc atgtccgtca aggaacctga ttttaacagc aatttgctgg
     9121 atcgtttctt ggttcttttg gagcacaagg gcatccatcc cattgtctat atttccaaaa
     9181 tggatttgtt ggaagatagg ggagaactgg atttttacca gcagacctat ggtgacatcg
     9241 gctatgactt tgtgaccagt aaagaggaac tcctgtcttt gttaacaggc aaggttacgg
     9301 tctttatggg gcagacaggt gttgggaagt caactcttct caataaaatc gcaccagacc
     9361 tcaatcttga aacgggagaa atttcagaca gtctaggtcg cggtcgccat accactcgag
     9421 ctgttagttt ttacaatctc aacgggggta aaatcgcaga tacaccaggc ttttcatctc
     9481 tggactatga agtatcaagg gctgaagacc tcaatcaggc ctttccagag attgctactg
     9541 ttagccgaga ttgtaagttc cgtacttgta cccataccca tgagccgtct tgtgccgtca
     9601 aaccagctgt tgaagagggt gttattgcaa ccttccgttt tgacaattac ctgcaattcc
     9661 ttagtgaaat tgaaaatcgt agagaaacct ataaaaaagt cagcaaaaaa attccaaaat
     9721 aaggagaaac ctatgtctca atacaagatt gctccgtcaa ttctggcagc agattatgcc
     9781 aactttgaac gtgaaatcaa acgtctagaa gcaactgggg cagaatatgc ccatatcgat
     9841 atcatggaca gtcattttgt accgcaaatc agttttggtg caggtgtggt cgagagcctt
     9901 cgtcctcata gtaagatggt tttcgattgc cacttgatgg tgtcaaaccc tgagcatcat
     9961 ctggaagatt ttgcgcgtgc aggtgcagac atcatcagta tccatgtaga agcaacgcct
    10021 catattcatg gcgccctcca aaaaattcgt tcactcggag ttaagccttc agtcgttatc
    10081 aatcctggca catcagttga agccatcaag cacgtccttc atctagttga ccaagtttta
    10141 gtcatgacgg ttaatccagg ttttggtggg caagcctttc tgccagaaac catggataag
    10201 gttcgtgagt tggttgctct tcgtgaggaa aaaggtttga actttgaaat cgaagtggat
    10261 ggtgggattg atgaccaaac tattgcccaa gccaaagaag ctggtgcgac cgtttttgta
    10321 gcaggttcct atgtctttaa gggagatgtc aatgagcgag tacaaactct cagaaaacaa
    10381 ctggactagg gttgccgttt ttgcaggcgg agaccgcggt cattatcgga cagattttga
    10441 tgcttttgtt ggggtggatc gaggctcgct ctgggtcttg gaagaagact tgcttcttgc
    10501 tctagcagtt ggggattttg attctgtgac cgaagaagag cgacaggtga ttcaaaaacg
    10561 tgcccagcat tttgtccaag cccgaccaga aaaagatgat accgatttgg aattggctct
    10621 cttaaccatc tttgagaaaa atcctcaggc tcaggttact attttcggtg ccttgggtgg
    10681 ccgtattgac catatgttgg ccaatgtctt tctgcctagc aatcctaagt tggcacccta
    10741 tatgcatcaa atagaaattg aggatgggca aaacttgatt acttattgtc cagaagggac
    10801 cagtcagcta gaacctcgtt cagactacga ctatctagcc tttatgccag ttcgggatag
    10861 ccagctgact attcttggag ccaagtatga gttgacagag gaaaattttt tctttaaaaa
    10921 agtgtacgct tctaacgaat atatagatag ggaagtgtcg gtaacttgcc cagatggtta
    10981 tgtggtcgta ctgcatagca aggacaggag gtaggatgga aagtttactt attctattat
    11041 taattgccaa cctagctggt ctctttctga tttggcaaag gcaggatagg caggagaaac
    11101 acttaagtaa gagcttggag gatcaggcag atcatttgtc agaccagttg gattaccgct
    11161 ttgaccaagc cagacaagcc agccagttag accaaaaaga tttggaagtg gttgtcagcg
    11221 accgtttgca agaagtgcgg attgaattgc accaaggtct gacccaagtc cgtcaagaaa
    11281 tgacagataa tctcctccaa actagagaca agacagacca acgtctccaa gccttgcagg
    11341 aatcaaatga gcaacgtttg gaacaaatgc gccagacggt cgaggaaaaa ctagaaaaga
    11401 ccttgcagac acgcttacag gcttcctttg agacagtttc taaacaactg gagtctgtca
    11461 atcgtggcct tggagaaatg cagacagttg cccgtgatgt cggagctctt aacaaggttc
    11521 tctctggaac caagacgcga gggattctgg gagaattgca actggggcaa attattgaag
    11581 acatcatgac acctgcccag tacgaacgag aatacgcaac ggttgaaaac tctagtgaac
    11641 gagtggagta tgccatcaag ttacccggac aaggcgacca agaatacgtc tatctgccaa
    11701 ttgactctaa gtttccactg gcagattatt accgcttgga agaagcctat gagacaggtg
    11761 acaaggatga gattgaacgc tgtcgtaagt cactcctagc aagcgtcaag cgctttgcca
    11821 aggatatcaa gagcaagtac atagcaccgc ctcggacgac caattttgga gttttgtttg
    11881 ttccgacaga aggtctttat tcagagattg tgcgcaatcc ggtcttcttt gatgatttga
    11941 gacgggaaga acagattatc gttgcaggac caagtaccct atcagccctt cttaactccc
    12001 tatcagttgg tttcaagacc cttaatatcc aaaagagtgc cgaccatatc agcaagactc
    12061 ttgccagtgt caagaccgag tttggcaagt ttggtggtat tctggtcaag gcacaaaaac
    12121 atctccaaca tgcctctggc aatattgatg aattattaaa ccgtcgtacc atagctatcg
    12181 agcggacgct ccgtcacatt gagttgtcag aaggcgagcc tgcgcttgat ctactccatt
    12241 ttcaagaaaa tgaggaagaa tatgaagatt agtcacatga aaaaagatga gctatttgaa
    12301 ggcttttacc taatcaaatc agctgacctg aggcaaactc gagctgggaa aaactaccta
    12361 gcctttacct tccaagatga tagtggcgag attgatggga agctctggga tgcccaacct
    12421 cataacattg aggcctttac cgcaggtaag gttgtccaca tgaaaggacg ccgagaagtt
    12481 tataacaata cccctcaagt caatcaaatt actctccgcc tgcctcaagc tggtgaaccc
    12541 aatgacccag ccgatttcaa ggtcaagtca ccagttgatg tcaaggaaat tcgtgactac
    12601 atgtcgcaaa tgattttcaa aattgaaaat cctgtctggc aacggattgt ccgaaatctc
    12661 tacaccaagt atgataagga attctactcc tatccagctg ccaagaccaa ccaccatgcc
    12721 tttgaaacgg gcttggccta tcatacggcg accatggtgc gtttggcaga cgctattagc
    12781 gaagtttatc ctcagctcaa taagagcctg ctctatgcgg ggattatgtt gcatgactta
    12841 gctaaggtca tcgagttgac ggggccagac cagacagagt acacagtgcg aggtaatctt
    12901 cttggacata tcgctctcat tgatagcgaa attaccaaga cagttatgga actcggcatc
    12961 gatgatacca aggaagaagt cgttttgctt cgtcatgtca tcctcagtca ccacggcttg
    13021 cttgagtatg gaagcccagt ccgtccacgc attatggaag cagagattat ccatatgatt
    13081 gacaatctgg atgcaagcat gatgatgatg tcaacagctc ttgctttggt ggataaagga
    13141 gagatgacca ataaaatctt cgctatggat aatcgttcct tctataaacc agatttagat
    13201 taataattta agaaaaatga gcatttttta ggataagaat gttcgttttt ttatgtgaat
    13261 atggtataat aagtaaaaga caaaaatgaa tactcttcga aaatctcttc aaactagggt
    13321 agtatcgcct tgtcgtatgt atatatgcag gtatattaca gggtttgtca gttctattga
    13381 caatctcaaa acagtgtttt gaaccaccag cgaccagctt tctagtttgc tttttgattt
    13441 tttgaataaa aatggaatag gaaatagaaa tgaaattaag aagaagtgat cggatggttg
    13501 tcatttccaa ctatttgatt aataatcctt ataaactaac tagtctcaat acttttgctg
    13561 aaaagtatga gtctgctaaa tcatccatct cagaagatat cgtcattatc aaacgcgcct
    13621 ttgaggaaat tgaaatcggt catatccaga cagtgactgg ggctggcgga ggtgtcatct
    13681 tcacaccgtc tatttcgagt caggatgcta aggaaatggt tgaagacttg cgtaccaagt
    13741 tgtcagaaag tgaccgtatc ttgccaggtg gttatatcta tctgtctgat ttgcttagca
    13801 caccagccat cttgaaaaat attggtcgta ttattgccaa aagctttatg gaccaaaaaa
    13861 ttgacgcggt tatgaccgta gcaactaagg gtgtgccact tgcaaatgca gttgccaatg
    13921 tcctcaatgt ctcttttgtc attgtgcgcc gtgacctgaa aattaccgaa ggttcaactg
    13981 ttagcgtcaa ctatgtttca ggttcaagtg gtgaccgtat cgagaaaatg ttcctttcaa
    14041 aacgtagtct taaggcaggt agccgtgtct tgattgtgga tgacttcttg aaaggtggcg
    14101 gaacggtcaa cggtatgatt agtctcttgc gcgagttcga ctcagaactg gcaggtgtag
    14161 cggtctttgc ggacaatgcc caagaagaac gtgaaaagca gtttgactac aagtcactct
    14221 tgaaggtaac taatattgat gtcaagaacc aagccatcga tgttgaggtt ggcaatatct
    14281 ttgacgaaga taaataagag atagaactaa aggttggaac gattgtccca gcctttcttt
    14341 gcaaacagaa tagaaggaag cttatgaaaa caccatttat caatagagaa gagttagaag
    14401 cgattgttgc cgagttcccg actccctttc acttgtatga tgagaagggg attcgtgaga
    14461 aggcaagagc cgtcaaccaa gctttttcgt ggaacaaggg ctttaaggaa tattttgcag
    14521 ttaaggctac tccaactcca gctattttga aaattctcca agaagaaggt tgtggtgtgg
    14581 actgctctag ttatgtagag cttttgatga gccataaact ggactttctg ggttctgaga
    14641 ttatgttctc ttccaacaac acgccagaca aggaatacgc ctatgcacgt gaattgggtg
    14701 cgaccattaa cttggatgcc tttgaagata ttgaacatct ggagagagta gcaggcattc
    14761 cagaaatcat ctcttgtcgt tataatcctg gaggcgtttt tgaactgggg acagacatta
    14821 tggacaatcc tggggaggct aagtttggca tgaccaagga ccagctcttt gaagcctttg
    14881 ctatcttgaa ggaaaaagga gccaagactt ttgggattca ctccttccta gcgtccaata
    14941 ccgtgaccca tctctattat ccagagttgg ctcgtcagct ctttgaactg gctgttgaaa
    15001 tcaaggaaaa gttgggcatt tggctagact ttatcaatct ttctggcggt attggtgtta
    15061 attatcgtcc agaccaggag ccgaacgata tcgccttgat tggtgaggga gttcgtaagg
    15121 tgtatgaaga agttcttacg tcagcaggtc ttggtcaggt caagattttc accgaattgg
    15181 gtcgttttat gctggcacct cacggtgctc tagtcacaag agtgactcat aagaaggaaa
    15241 cctaccgtac ctatctaggt gtggatgcct cagcagtcaa cctcatgcgt ccagctatgt
    15301 acggagctta ccatcatatt agcaacgtga cccatccaga tggaccagct gaagcggtag
    15361 atgtggttgg ttcactctgt gaaaacaatg ataaatttgc agtcaatcgc gaactgcctc
    15421 atacagaaat cggtgatttg ctggtaattc atgatacagg tgcccacgga ttttcaatgg
    15481 gctaccagta taatgccaaa ttacgttctg cggaaatcct ctataccgaa gaaggtaaag
    15541 cccgtcaaat ccgccgtgca gagcgccctg aggactattt tgcaacctta tatggcttcg
    15601 attttgaaga ataatctgat aatagattga aaatgaaatt gaaaaacaga ttgctttcta
    15661 aaaaataggc aaaaatcttg tttttccttc aagtcgtgat ataataaaac tataaaacgt
    15721 tttcaaggaa ggtaacgata tgtctgaaga aacaattgat tatggacaag tgacaggaat
    15781 ggtgcattcg acagaaagct ttgggtcagt agatgggcct ggtattcgct ttattgtctt
    15841 tttgcagggc tgtcacatgc gttgccagta ttgccacaac ccagacactt gggctatgga
    15901 gtccaataag tcacgtgaac ggacggtaga tgatgtcttg acagaggcct tgcgctaccg
    15961 tggtttctgg ggaaataagg gtgggattac agtcagtgga ggagaagctc tcttgcagat
    16021 tgatttcctg attgctctct tcaccaaggc taaggaacaa ggaatccact gtaccttgga
    16081 tacctgtgct cttcctttcc gtaataaacc acgttacctt gagaagtttg acaaactcat
    16141 ggctgtcact gacttggttc ttttggatat caaggaaatc aacgaagaac agcacaagat
    16201 tgtcactaga caaaccaata aaaatatctt ggcttgtgcc cagtatctat cagatattgg
    16261 aaaacctgtc tggattcgcc acgtgctagt tccaggattg acagacagag atgatgactt
    16321 gattgaactt ggtaagttcg tcaagaccct caaaaatgtt gataagtttg aaattctacc
    16381 ttatcacacc atgggtgagt tcaagtggcg tgaacttgga attccatatt ccctcgaagg
    16441 agtcaaacca ccaacagcag atcgcgtcaa gaacgctaaa aaactcatgg ataccgaaag
    16501 ttatcaagat tatatgaaac gtgtacatgg atagaaaaga agcctgatgg aaacatcggg
    16561 cttttgattt gcaaaaagac ttagcaaatc agctaagcct ttttcttctt atctcgaacg
    16621 ttgttttcca gcgttgcgat ttttgtgttt tttcttgctt gtgatagcag ttggttgttc
    16681 aggggtaacg tcttttcgtc cacttggttt agagaaagca cttgcttttg gtgggttctt
    16741 ggctagttct tcacggactt ttttgcgaag ttttggacga acgatatagt tgacgataaa
    16801 ctgttggaga atcatcatga aaccaccgac aacccagtaa agtgtgacac tagctggtga
    16861 gaagagggag aagacgacga tcatgagtgg gctcatgtaa atcattttct tgatttgttc
    16921 tctttgcatt tcatcttcta ctccgtgaag tgaaaggagc gattgaagat agtaaaggac
    16981 accagcacag gcaaccaaaa tcatacttgg agaacctaga ggaatgccta ggtagcttgc
    17041 ttgagcaacc ccttcagtat gttgggcagc aaagtagata gcagagaaga aaggcatttg
    17101 aaggaggata gggaaacatc ctacaccgcc aaacatgctg ataccgtgct ctttttgagc
    17161 agcaaagaga gcttgttggg cttcgagttt ttcttcttga gtagtcgctt ctttgagacg
    17221 cgtttggtgt ggctcaagga cgtgcttgag ggcgttcatc ttttcagagt gaagcgttgc
    17281 cttccatgat tggtagatac caagtggcaa gataatcaag cgcacgataa tggttacgat
    17341 gatgatagcg acaccaaagc ctagaccttt atcagtagcg aagtacttga tagcttcagc
    17401 cataggggct ccgatggtat tccaaataaa tcctgttggc tgacctgtgg ttttatcgac
    17461 attgacacaa ccagtcaaga caagcaacat agccgctccc atagctgaga gtgcaaaacg
    17521 tttaatagat ttcactgttt ttattccttc tttaaaaatt atacctttct attctactgt
    17581 ttttttacaa aatatacaat agttctggag acctaatttg cgattttaaa gtcagagtag
    17641 ggaggaaagt tgcttagttt gacatctaag tagcttactt ttgaaaaagg tgtcggtcct
    17701 tttcggattt cttggataaa ttttgccatg atagcagatg agtctgcttg ggctaagatt
    17761 tccactgtgc catcgtcgtt attccatact cgacctgtga tgccaccaat ttcaagtgcc
    17821 aagctgtaaa caccccaacg aaagccgact ccctgtaccc taccttgggc aatcattcta
    17881 accttttgca taccaaaccc ctttgattgt gttataatat ttctatgact attataacct
    17941 caaaagccaa ttctgtggta aaaaatgcca agaaattacg ccaaaaaaaa taccgcaagt
    18001 ctgcctactt gattgaaggc tggcacttgt ttgaagaagc tgtccaagct ggagtgacga
    18061 ttgagaaaat ctttgcccta gaaaattatc gagatcagtt agctactttt tcgcaaactg
    18121 tctgggtgtc agaggatatt ttgctagatt tggcggattc tcagactcca cagggaattg
    18181 ttgccgtggt tcaaaaagaa gaagtaggac aagctgattt gagtcagggc aagttcttgt
    18241 ttttggaaga tgtgcaagat cctggtaatg taggaactat cattcgaact gcggatgcag
    18301 caggttttac aggagtgatt gtttcagata agtcggcaga catctacagt ctcaaaaccc
    18361 tacgttccat gcaaggtagt catttccatc tgcccattta ccggatgact agtcaagcgc
    18421 ttcttgacga aactaaaaag gtagctatcc cagtgctagc aacaacccta tctaaagatt
    18481 ctgttgatta cagagaactg ccttctatag aaaattttgt actagttatg ggaaatgagg
    18541 gtcaaggaat tagtcccctt atggctgaaa gtgcagacca gttggtccat attagcatga
    18601 aggggcaggc cgagagtttg aatgttgcgg ttgcagccgg tattttaatc ttccatttaa
    18661 gctaatttta actttttttg ttataatcaa ggaaagatgt tcacagaaaa ggagaaatgg
    18721 atgaatcaca ctattataca tgaccgtgca ggtctcaatc aattttacgc taaggtttat
    18781 gcctttgttg gtctgggaat cggactatct gctttggtat caggccttat gttgacggtc
    18841 tttcagtctc agttggttta ctttttgatg caggggcgtc tctggttgac cattgctact
    18901 tttgcggagt tggctttggt tttcgttgcc agtagcatgg cttcaagaaa tagtccagct
    18961 gctcttccag tatttttact ttactccgtt ttaaacggct ttacccttag ttttgtggtg
    19021 gctttctata ctccgggtac agttttatct gcctttgtat cgagcgccct tctcttcttt
    19081 gtcatggcgg cagttggtat ttttaccaag aaagacttga gtgggattgg tcgagcaatg
    19141 atggcagctc tcattggttt actgattgct atggtagtca atattttctt ggctagtggc
    19201 ttctttgatt atatgattag cgtagccatg gttttggttt tttcagggtt gattgcttgg
    19261 gataaccaaa agattcgcct cgcctatgaa caatcacaag gtcgtgtagc gacaggctgg
    19321 gtggtgtcaa tggctctcag catctatctt gattttatca atcttttcct aagtattcta
    19381 cgtatctttg gtcgcaatga ctaaaaggtc tatgaaatca gtgttttgag tgacactgat
    19441 tttttttaaa attttctctt ttcttttctt ggaaataggt gtataatacg tttattaaat
    19501 ttttgaggag ttgtctatga agaaaagttt tatccatcaa caagaagaaa tttcctttgt
    19561 caaaaacact tttacccagt atttgaaaga taagctagaa gttgtcgaag ttcaaggtcc
    19621 tatcttgagt aaggtcggtg acggaatgca ggacaacctg tctggtgtgg aaaatccagt
    19681 atcggtcaag gttctccaaa tccctgatgc tacttatgaa gtggtgcact cacttgctaa
    19741 atggaaacgc cacaccttgg ctcgttttgg ctttggtgaa ggagagggtc tctttgtcca
    19801 catgaaagcc cttcgtccag atgaggattc cttggatgca acccactctg tttatgttga
    19861 ccagtgggac tgggagaagg ttatcccaaa tggtaagcgt aacatcgttt atctaaaaga
    19921 aacagttgag aagatttata aggctattcg cctgactgag ctagctgttg aagcccgcta
    19981 tgacatcgag tctatcttgc caaaacaaat cacctttatc catacagaag aattggtaga
    20041 acgctaccca gacttgacac cgaaagaacg tgaaaatgcg atttgtaaag aatttggagc
    20101 cgtctttttg attggtatcg gtggcgagtt gccagatggt aaaccgcacg atggacgtgc
    20161 accagactat gatgactgga caagcgagtc tgagaatggc tacaagggtc taaatggtga
    20221 tattcttgtc tggaatgagt ctttaggtgg agcctttgag ttgtcttcta tgggaattcg
    20281 tgtagatgaa gaaactctta gacgtcaggt ggaaattaca ggtgatgaag accgcttgga
    20341 attggaatgg cacaagtctt tgttgaatgg tctattccca ttgacaatcg gtggaggaat
    20401 tggacaatct cgtatggcca tgttcctact tcgcaagaga cacatcggag aagtgcaaac
    20461 aagtgtttgg cctcaagaag tccgcgatac ttacgaaaat attttgtaga gaatcgaacc
    20521 gcaaggttcg gttttctttc tctttttgtc tataatttgg tataataaac agtatgaaaa
    20581 tcgtatcagg aatctatggg ggacgtcccc tcaagacact agaaggcaag acgacaagac
    20641 ctacttcgga taaggttagg ggagccattt ttaacatgat tggtccctac tttgaagtgg
    20701 gacgagtctt ggacctttat gcaggtagtg gtggtttatc tatcgaagca gtatcgcgtg
    20761 gcatgtccag tgctgttttg gtggagcgag accgtaaggc tcagaccatc gtggctgaaa
    20821 atatccagat gaccaaggaa gttggaaaat ttcaactcct aaagatggat gcagaaaggg
    20881 cattggaaca ggtatctggg gaatttgacc tcgttttctt agaccctccc tatgccaagg
    20941 aacaaatcgt agcagatatt gaaaaaatgg ctgagagaga gcttttttct gaagatgtta
    21001 tggttgtgtg cgagacggat aaagccgttg aacttccaga agaaattgcc tgtctgggta
    21061 tctggaagga aaagatttat ggaattagta aggtgacagt ctatgtcaga taagattggc
    21121 ttattcacag gctcatttga tccgatgaca aatgggcatc tggatatcat tgaacgggcg
    21181 agcagacttt ttgataagct ttatgtgggt atttttttta atccccacaa acaaggattt
    21241 ctccctcttg aaaatcgtaa acgggggcta gaaaaggctt tgggacattt ggaaaatgtt
    21301 gaagtcgtgg cttctcatga tgaattggtg gtcgatgttg caaaaagatt gggtgctact
    21361 tgtctagtgc gtggtttgag gaatgcgtcg gatttgcaat atgaagccag ttttgattac
    21421 tacaatcatc agctgtcttc tgatatagag actatttatt tacatagtcg acctgaacat
    21481 ctctatatca gttcatcagg cgttagagag cttttgaagt ttggtcggga tattgcctgc
    21541 tatgttcccg agagtatttt ggaggaaata agaaatgaaa aaaaagatta gatggccctt
    21601 atacgtcatt gcggccttga ttgtgacttt cttggcattt gtagtgccct tgccttatta
    21661 tatagaggtt ccaggtggtt cggaagatat tcgccaagtc cttaaaataa atgacacaga
    21721 agataaggaa gctggtgcct atcaattcgt tacggttggt gttcaacatg ccactttagc
    21781 tcatatgatt tatgcttggt tgacaccttt tacagatatt cgtagtgctc aggagactac
    21841 aggtggttct tccgatgttg aatttatgcg aatcaatcaa ttctacatgc aaacatcgca
    21901 aaatatggcc aagtatcaag gactaaaaac agctggtaag gatatcgaac tcaagtactt
    21961 tggagtttat gttttgaatg tgacggataa ttcaaccttt aaagggattc tcaatatctc
    22021 tgatacagtc acagcagtca atgatcagac ctttgatagt tccaaagact tgattgatta
    22081 cgtcagttct caaaaattag gggattccgt caaggtcacc tatgaagagg atgggcaaac
    22141 caagtctgca gaaggaaaga ttatcacctt ggaaaatggc aaaaatggaa ttggaatcgg
    22201 cttgattgac cgtacagagg taatcagcaa tgtcccaatt agcttttcaa cagctggtat
    22261 tggcggtcca agtgctggtc tcatgtttag tctagctatc tatactcaaa tagctcaccc
    22321 agatcttcgt aatggtcgta ttgttgccgg tacaggtacc attgaccgcg atggtaatgt
    22381 gggagacatt ggaggtattg ataagaaggt tgtagcttcg gctagggcag gtgctgctat
    22441 tttctttgct cctgataacc ctgttagcga agaagaacaa aaggcgcatc cggacgcgaa
    22501 aaacaactac caaacagccc tagaagcggc taaaacaatc aagacggata tgaaaatcgt
    22561 gcccgttaaa accctacaag atgcgattga ttacttgaaa aacaatccct aatttttgag
    22621 tgaagtttcc aaactagcgc acaaacagag aagatggtat aatagtcaaa tggttcaatt
    22681 attattcact ctaagtagtc atatgctctt tatttatgtg agtttttacc ttttaaagga
    22741 tcttgttaga tgggagaagg ttttaaaagt gacagatgag aatacaagaa aagttcgttt
    22801 attagtagcc ttttttagca ttgtcatagg ctacatcctg agttctttct ttattagcct
    22861 gtatcatttg tggcaagaag cgcttagagg attattatga aatcaagagt aaaggaaacg
    22921 agtatggata aaattgtggt tcaaggtggc gataatcgtc tggtaggaag cgtgacgatc
    22981 gagggagcaa aaaatgcagt cttacccttg ttggcagcga ctattctagc aagtgaagga
    23041 aagaccgtct tgcagaatgt tccgattttg tcggatgtct ttattatgaa tcaggtagtt
    23101 ggtggtttga atgccaaggt tgactttgat gaggaagctc atcttgtcaa ggtggatgct
    23161 actggcgaca tcactgagga agccccttac aagtatgtca gcaagatgcg cgcctccatc
    23221 gttgtattag ggccaatcct tgcccgtgtg ggtcatgcca aggtatccat gccaggtggt
    23281 tgtacgattg gtagccgtcc tattgatctt catttgaaag gtctggaagc tatgggggtt
    23341 aagattagtc agacagctgg ttacatcgaa gccaaggcag aacgcttgca tggcgctcat
    23401 atctatatgg actttccaag tgttggtgca acgcagaact tgatgatggc agcgactctg
    23461 gctgatgggg tgacagtgat tgagaatgct gcgcgtgagc ctgagattgt tgacttagcc
    23521 attctcctta atgaaatggg agccaaggtc aaaggtgctg gtacagagac tataaccatt
    23581 actggtgttg agaaacttca tggtacgact cacaatgtag tccaagaccg tatcgaagca
    23641 ggaaccttta tggtagctgc tgccatgact ggtggtgatg tcttgattcg agacgctgtc
    23701 tgggagcaca accgtccctt gattgccaag ttacttgaaa tgggtgttga agtaattgaa
    23761 gaagacgaag gaattcgtgt tcgttctcaa ctagaaaatc taaaagctgt tcatgtgaaa
    23821 accttgcccc acccaggatt tccaacagat atgcaggctc aatttacagc cttgatgaca
    23881 gttgcaaaag gcgaatcaac catggtggag acagttttcg aaaatcgttt ccaacaccta
    23941 gaagagatgc gccgcatggg cttgcattct gagattatcc gtgatacagc tcgtattgtt
    24001 ggtggacagc ctttgcaggg agcagaagtt ctttcaactg accttcgtgc cagtgcagcc
    24061 ttgattttga caggtttggt agcacaggga gaaactgtgg tcggtaaatt ggttcacttg
    24121 gatagaggtt actacggttt ccatgagaag ttggcgcagc taggtgctaa gattcagcgg
    24181 attgaggcaa gtgatgaaga tgaataagaa atcaagctac gtagtcaagc gtttactttt
    24241 agtcatcata gtactgattt taggtactct ggctctagga atcggtttaa tggtaggtta
    24301 tggaatcttg ggcaagggtc aagatccatg ggctatcctg tctccagcaa aatggcagga
    24361 attgattcat aaatttacag gaaattaggc tggagaacca gcctttttct aaagataagg
    24421 agaaatatga acaaaaaaac aagacagaca ctaatcggac tgctagtgtt attgcttttg
    24481 tctacaggga gctattatat caagcagatg ccgtcggcac ctaatagtcc caaaaccaat
    24541 cttagtcaga aaaaacaagc gtctgaagct cctagtcaag cattggcaga gagtgtctta
    24601 acagacgcag tcaagagtca aataaagggg agtctggagt ggaatggctc aggtgctttt
    24661 atcgtcaatg gtaataaaac aaatctagat gccaaggttt caagtaagcc ctacgctgac
    24721 aataaaacaa agacagtggg caaggaaact gttccaaccg tagctaatgc cctcttgtct
    24781 aaggccactc gtcagtacaa gaatcgtaaa gaaactggga atggttcaac ttcttggact
    24841 cctccaggtt ggcatcaggt caagaatcta aagggctctt atacccatgc agtcgataga
    24901 ggtcatttgt taggctatgc cttaatcggt ggtttggatg gttttgatgc ctcaacaagc
    24961 aatcctaaaa acattgctgt tcagacagcc tgggcaaatc aggcacaagc cgagtattcg
    25021 actggtcaaa actactatga aagcaaggtg cgtaaagcct tggaccaaaa caagcgtgtc
    25081 cgttaccgtg taacccttta ctacgcttca aacgaggatt tagttccctc agcttcacag
    25141 attgaagcca agtcttcgga tggagaattg gaattcaatg ttctagttcc caatgttcaa
    25201 aagggacttc aactggatta ccgaactgga gaagtaactg taactcagta aaagataagc
    25261 ctaaactcct atgtcactta tggatgtagg agttcttttt actagtttaa gcagggctag
    25321 aacaggtact aagaaaaaat agcaacttct aaaactaact tccagttttg ggagagagat
    25381 ggaagttact ttgagaagtt acggtaagaa aaaataatat gtattggatt aaattttgtg
    25441 atataataaa ggataagata ctattttagg agaagaacta tggaagaccc aagtagtcag
    25501 aatttgttgc tacaatttgt tttattgttt atcttgacgg tattaaatgc ctttttctca
    25561 gccacagaaa tggccatggt ttctcttaat cgtgcccgag ttgaacaaaa ggcggaagaa
    25621 ggagacagac gctacatccg cctgctgaag gtactagaaa atcctaacca ctttttatca
    25681 accattcagg taggaatcac cctgattaca atcttatcag gggcgagttt aactaatact
    25741 ctaggacgtg tgattgcctc ttggcttggg aatggcgaaa cagcacaagc cgtggcaact
    25801 tttctatcct tggcattttt gacctatatt tccatcgttt ttggggaatt atatcctaag
    25861 agaatcgctc ttaatctaaa ggatgccttg gcaattcgta tagcgccggt tatcattggg
    25921 atcggaaaac tagtcagtcc ttttgtttgg cttttagctg cttcgaccaa tttcttgagc
    25981 catttgactc ctatgtcatt cgatgatgcg gatgaaaaga tgacccgtga tgaaattgcc
    26041 tatatgctga caaatagtga agaaacattg gatgctgatg agattgagat gctacaaggt
    26101 gtcttttcgc tcgatgaact gatggcacga gaggttatgg ttcctcgaac ggatgccttt
    26161 atggtggata ttcaggatga tagtcaagcc attatccaaa gtattttaaa acaaaattat
    26221 tctcgtatcc cggtttatga tggggataag gacaatgtaa ttggaatcat tcacaccaag
    26281 agtctcctta aggcaggctt tgtggacggt tttgacaata ttgtttggaa gagaattttg
    26341 caagatccac tttttgtacc tgaaactatt tttgtggatg acttgctaaa agaactgcga
    26401 aatacccaaa gacaaatggc aatcttgctg gatgaatacg gtggtatggc tggtttggtg
    26461 actttggaag acctcttaga ggaaattgtt ggtgaaattg atgatgaaac ggacaaagca
    26521 gcaatagatg ttcatcagat tggcgaggat acctacattg ttcaaggaac tatgaccctc
    26581 aatgatttca ataattactt tgatgttgaa ctggaaagtg atgacgttga taccatcgct
    26641 ggttattatt tgacaggagt gggaactatt ccaacgactg agaaactcag ctatgaattg
    26701 gttagccaaa acaaacagtt tatcttaacc aatgataaag tgaagaatgg acgtgttacc
    26761 aaggtaaaag tccaaatcac agaagtcgaa atagaagaag aaacagaata aactagaggc
    26821 ttttgtcacc aggcgtgacg aagctttttt caattgattt caaaagggaa ttatgccatg
    26881 gaaagaactc tgccacaaac tcgctccaaa agtttttaaa gttatacgta tttattcgag
    26941 ggaaaataaa aaaagccctt caaattgggc tttctgttca tttgaaacct gataaatcaa
    27001 gttatagaag gcggtagacg gatttgaacc gacgatcaag cttttgcaga gccgtgcctt
    27061 accacttggc tataccgcct taacgtttat tattatacct tgaaaatgat tttcagtcaa
    27121 tagttttttc agttttttgt accatagcgt gattcgaatg tgatgccaag ttttctatgg
    27181 gaaaaaattt accaaaaacc tactaaaacc ccttgaaaaa tctagctaaa tagggtataa
    27241 tatgggtaat catttgtcgt aggttttgtc tgaaatattg tccagacaag gctcacagca
    27301 gttaaatctt ctgaaaaagt cagatttagc tgctcttttt gtgctttttt tcaagatttt
    27361 gagcatttgt aacagaggct taaagattct gaaaattcgt caagaggaca cggtgataag
    27421 gggtttacaa ccatatgacg attagaaaag cctgattgac aaggcttgga acttatttac
    27481 aaaggagaat catcttggca ggacatgacg ttcaatacgg gaaacatcgt acccgtcgta
    27541 gtttttcaag aatcaaagaa gttcttgact taccaaattt gattgaaatt caaactgact
    27601 cattcaaagc tttcctagac cacggtctta aggaagtgtt tgaagatgta ttgccaattt
    27661 caaacttcac agacacaatg gagttggaat ttgttggata tgaaatcaag gaaccaaaat
    27721 atacgctaga agaagctcgt atccacgatg ctagctactc agcaccaatt tttgtaacct
    27781 tccgtttgat caataaagaa acaagcgaaa tcaagaccca agaagttttc tttggtgatt
    27841 tcccaatcat gacagaaatg ggtactttca tcatcaatgg tggtgaacgt attatcgttt
    27901 ctcagttggt ccgctcacca ggtgtttact ttaacgacaa agtagacaaa aatggtaagg
    27961 tgggctatgg ttcaactgtt atccctaacc gtggagcttg gttggaactt gaaagcgact
    28021 caaaagatat cacctacact cgtatcgacc gtactcgtaa gattccattt acaaccttgg
    28081 ttcgtgctct tggtttctca ggtgatgatg aaatctttga tatctttggt gacagcgaat
    28141 tggttcgcaa cactgttgaa aaagatatcc acaagaatcc aatggactct cgtacagacg
    28201 aagccttgaa agaaatttac gaacgccttc gtccaggtga gcctaagacg gctgaaagct
    28261 cacgtagctt gcttgtagct cgcttctttg acccacgtcg ttatgacttg gcagcagttg
    28321 gtcgttacaa aatcaataaa aaactcaatg ttaaaacacg tttactcaac caaaccattg
    28381 cagagccatt ggtagaccct gaaactggag aaatcttggt agaagctggt acgattatga
    28441 ctcgtagcgt gattgaaagc attgaaagcc atttggatgg cgacttgaac aagattgtct
    28501 acatcccaaa cgatgcagcc gttgtgactg agcctgttgt tcttcaaaaa ttcaaggtta
    28561 ttgctccaac tgatccagat cgcgtcgtaa cgatcattgg taatgctaac ccagatgaca
    28621 aggttcgtac ggtgactcct gcagatatcc ttgctgagat gagctacttc ctcaacttgg
    28681 ctgaaggact tggccgtgta gatgatatcg accaccttgg aaatcgtcgt atccgtgcgg
    28741 ttggtgaatt gcttgccaac caagtacgtt tgggactttc tcgtatggaa cgtaatgtcc
    28801 gtgaacgtat gtctgttcag gacaatgaag tcttgacacc acaacaaatt atcaatattc
    28861 gtcctgtaac agctgcagtt aaagaattct ttggttcatc acagttgtca cagttcatgg
    28921 accaacacaa cccgctttct gagttgtctc acaaacgccg tttgtcagcc ttaggacctg
    28981 gtggtttgac tcgtgaccgt gctggatatg aagtgcgtga cgtgcactac actcactatg
    29041 gtcgtatgtg tccaatcgag acacctgaag gacctaacat cggtttgatc aataacttgt
    29101 catcttacgg acacttgaac aaatatggtt ttgttcaaac accataccgt aaggttgacc
    29161 gtgaaacagg tgttgtcacg aacgaaattg tttggttgac agctgatgaa gaagatgaat
    29221 atactgtagc tcaggctaac tctcgtctga atgaagatgg aacctttgct gagaagattg
    29281 tcatgggacg tcaccaaggg gtcaaccaag agtatccagc taatattgtt gactacatgg
    29341 acgtttcacc aaaacaggta gttgccgttg cgacagcatg tattcctttc ttggaaaacg
    29401 atgactccaa ccgtgccctc atgggagcca atatgcaacg tcaggctgtg ccactgatta
    29461 atcctcaggc accttacgtt ggtactggta tggaatacca agcagcccac gattctggtg
    29521 cggctgtgat tgctcagtat gatggtaaag ttacttacgc agatgctgac aaggtagaag
    29581 ttcgtcgtga agatggttca ttggatgttt accacatcca aaaattccgt cgttcaaact
    29641 caggtactgc ttacaaccaa cgcactctcg taaaagttgg tgatgtcgtt gaaaaaggcg
    29701 atttcatcgc tgacggacct tctatggaaa atggagaaat ggcgcttgga caaaacccaa
    29761 tcgttgccta catgacttgg gaaggttaca acttcgagga tgccgttatc atgagcgaac
    29821 gcttggtgaa ggacgatgtc tacacatctg ttcaccttga agaatacgaa tcagaaacgc
    29881 gcgatacaaa gcttgggcct gaagaaatca ctcgcgaaat tccaaacgtt ggtgaagatg
    29941 ccctcaaaga ccttgacgaa atggggatta tccgtattgg tgctgaggtt aaagaaggtg
    30001 atattcttgt aggtaaagta acacctaagg gtgagaaaga tctttcagct gaagaacgtc
    30061 tcttgcacgc tatctttgga gacaagtctc gtgaagtgcg tgatacttct cttcgtgtac
    30121 cacacggtgc cgatggtgtc gttcgtgatg ttaagatctt tacacgtgta aatggagatg
    30181 agttgcaatc aggtgttaac atgttggttc gtgtttacat cgctcaaaaa cgtaagatta
    30241 aggtcggaga taaaatggcc ggacgtcacg gaaacaaagg ggttgtctct cgtatcgttc
    30301 ctgtagaaga catgccttac cttccagacg gaactccagt cgacatcatg ttgaacccac
    30361 ttggggtacc atcacgtatg aatatcggtc aggttatgga gcttcacctt ggtatggcag
    30421 ctcgtactct tggtattcac atcgctacac cagtctttga tggagcaagt tctgaagatc
    30481 tttggtcaac tgttaaagaa gcaggtatgg atagcgatgc caaaacgatc ctttacgatg
    30541 gacgtactgg tgaaccgttt gataaccgtg tttctgtcgg agtcatgtac atgatcaaac
    30601 tccaccacat ggttgatgat aaattgcacg cgcgttcagt cggaccatac tcaactgtta
    30661 cccaacaacc actcggaggt aaggctcagt ttggtggaca acgtttcggt gagatggagg
    30721 tttgggctct tgaagcctac ggtgcgtcaa atgtccttca agaaatcttg acttacaagt
    30781 cggacgatat caacggacgt ttgaaagcct atgaagctat tacaaaaggc aaaccaattc
    30841 caaaaccagg tgttccagaa tccttccgag ttcttgtcaa agaattgcaa tctcttggtc
    30901 ttgacatgcg tgtcctagac gaagatgacc aagaagtgga acttcgcgac ttggatgaag
    30961 gaatggacga agatgtcatc cacgtagatg accttgaaaa agcccgcgaa aaagcagccc
    31021 aagaggctaa agcagccttt gaagctgaag aagctgagaa agcaacaaaa gcggaagcaa
    31081 cagaagaagc tgctgaacaa gaataagcag ttcacttaga atagaaaggg aagaaatagt
    31141 ggttgatgta aatcgtttta aaagtatgca aatcacccta gcttctccaa gtaaagtccg
    31201 ttcatggtct tatggagaag tcaaaaaacc tgaaacaatc aattatcgta ccttgaaacc
    31261 agaacgtgaa ggactctttg atgaagtgat ctttggtcct acaaaagact gggaatgtgc
    31321 ttgtggtaag tacaaacgca ttcgttacag aggaattgtt tgtgaccgct gtggggttga
    31381 agtaacgcgt acgaaagttc gtcgtgagcg tatgggacat atcgaattga aagctcctgt
    31441 atctcacatc tggtacttca aggggattcc aagccgtatg ggcttgaccc ttgatatgag
    31501 ccctcgtgcc ctcgaggaag ttatctactt tgcggcttat gtggtgattg atcctaagga
    31561 tacaccactt gagcacaagt ctatcatgac agagcgcgaa taccgagagc gcttgcgcga
    31621 atatggttat ggttcatttg ttgctaagat gggtgcggaa gccatccaag accttttgaa
    31681 gcaagtagat cttgaaaaag aaattgctga actcaaagaa gaattgaaaa ctgctactgg
    31741 acaaaaacgt gtcaaagcca tccgtcgttt ggatgttttg gatgcctttt acaagtctgg
    31801 aaacaaacct gaatggatga ttcttaacat ccttccggtt atcccaccag atcttcgtcc
    31861 aatgttgcag ttggatggtg gccgttttgc ctcatctgac ttgaatgacc tttaccgccg
    31921 tgttatcaac cgtaacaacc gtttggctcg tttgcttgag ttaaatgcac caggtatcat
    31981 cgttcaaaat gagaagcgta tgcttcaaga agcagttgac gctttgattg acaatggtcg
    32041 tcgtggtcgt ccaatcacag gaccaggtag ccgtccattg aaatcattga gccacatgct
    32101 taaaggtaaa caaggacgct tccgtcaaaa cttgctcggt aaacgtgttg acttctcagg
    32161 acgttccgtt atcgccgttg gtccaactct taagatgtac caatgtggtg tgccacgtga
    32221 aatggcgatt gaactcttta aaccatttgt catgcgtgaa atcgttgccc gtgatatcgt
    32281 gcaaaacgtc aaagcagcta aacgcttggt ggaacgcgga gatgagcgta tctgggatat
    32341 ccttgaagaa gtgattaaag aacacccagt gcttttgaac cgcgcaccga cccttcaccg
    32401 tttgggtatc caagccttcg agccagtctt gattgatggt aaggctcttc gcttgcaccc
    32461 acttgtctgt gaagcctaca atgctgactt tgacggggac caaatggcca tccacgtacc
    32521 actttcagaa gaagcacaag cagaagctcg tatcctcatg ctagctgctg agcacatctt
    32581 gaacccgaaa gatgggaaac cggtagttac tccatctcag gacatggttt tgggtaacta
    32641 ctacttgacc atggaagaag ctggtcgcga aggtgaagga atggtcttca aagaccgtga
    32701 cgaagcggtt atggcttacc gcaatggtta tgttcacctc cactcacgtg ttggtatcgc
    32761 aacagacagc ctcaacaagc cttggacaga agagcaaaga cataaggtct tgcttacaac
    32821 agttggtaaa attctcttca acgatatcat gccagagggg ctaccatact tgcaagaacc
    32881 aaacaatgcc aacttgacag aaggtgttcc agctaaatac ttcttgccac ttggtggagc
    32941 tatcaaggaa gctatcagca atcttgagct caaccctcca ttcaagaaga aaaacctcgg
    33001 aaatatcatc gctgaaatct tcaaacgttt ccgtacgaca gaaacttctg ccctacttga
    33061 ccgcatgaag aacctcggtt accaccactc aactcttgca ggattgacag tgggtattgc
    33121 cgatatccca gtcgttgatg acaaggctga aatcattgaa gaatcacaca aacgtgtcga
    33181 acaaatcacc aaacaattcc gtcgtggtat gatcacagac gacgagcgtt acaatgctgt
    33241 tacagctgaa tggcgtgctg cccgtgaaaa acttgagaaa cgcttgattg ctaatcaaga
    33301 tcctaagaac ccaatcgtta tgatgatgga ctctggagcc cgtggtaaca tctcaaactt
    33361 ctcacagctt gccggtatgc gtggtctgat ggctgctccg aatggacgta tcatggaatt
    33421 gccaatcctt tcaaacttcc gcgaaggttt gtcggtattg gaaatgttct tctcaactca
    33481 cggtgctcgt aaaggtatga ccgatacggc ccttaagaca gccgactcag gttacttgac
    33541 tcgtcgtttg gtcgacgttg cccaagacgt tatcatccgt gaggacgact gtggaactga
    33601 ccgtggtctc ttgatccgtt ctatcgcaga aggaaaagag atgatcgagt ctctcgaaga
    33661 gcgtctcaac ggtcgttaca ctaagaaaac tgttaaacat ccagaaactg gtgcagtgat
    33721 tattggtcca aatgaattga ttacagaaga caaggcgcgt gaaattgtca atgctggtgt
    33781 ggaagaagtg actatccgtt ctgtatttac atgtaacact cgtcacggtg tctgccgtca
    33841 ctgttacggt atcaacttgg cgactggtga tgcggttgaa gttggtgaag cagttggtac
    33901 aatcgctgcc caatctatcg gggaacctgg tacacagctt acaatgcgta ccttccacac
    33961 aggtggggtt gcctcaaata ccgatatcac tcagggtctt cctcgtgtcc aagaaatctt
    34021 tgaagcccgc aatcctaaag gggaagcggt tattacagag gttaaaggac aagttactgc
    34081 tatcgaagaa gatgcatcaa ctcgtaccaa gaaagtcttt gttaagggtg aaactggcga
    34141 aggtgaatat gtcgttccat ttacagctcg tatgcgtgtc gaagttgggg gccaagtagc
    34201 gcgtggtgct gctctgacag aaggttctat ccaaccaaaa cgtctccttg cagttcgtga
    34261 tgtcttgtca gttgaaacgt accttctcgg tgaagtacaa aaagtttacc gtagccaagg
    34321 ggtagaaatc ggtgacaaac acatcgaggt aatggttcgt caaatgatcc gtaaagtccg
    34381 tgtcatggat ccaggtgata cagatcttct catgggtacc ctcatggata tcaatgactt
    34441 tacagatgcc aacaaagatg tccttatcgc aggtggagtt ccagcgacag gtcgcccagt
    34501 ccttatggga attaccaaag cctcacttga aacaaacagt ttcttgtcag cggcttcctt
    34561 ccaggaaaca actcgtgtcc ttactgacgc agctatccgt ggtaagaaag accatctcct
    34621 tggacttaaa gaaaatgtta tcatcggtaa gatcatccca gctggtactg gtatggcccg
    34681 ttaccgtaac cttgaaccac atgctgtcaa cgaagaagaa taccttaatc ctccagtaga
    34741 ggaagaagga aatgaagaaa caacagaagt agttgtggat actgccgttg aaactgtgga
    34801 agaaacagta gaataagaga gaatgagaga acccgagggt tctctcattc tctcttctga
    34861 aaactttctc catttttcca cgaaatgtgg taaaataaaa gaaagaagct gacaaaggag
    34921 acgggtatgg aacaaacatt ctttatcatc aaaccagatg gtgtaaaaag agggctagtg
    34981 ggtgaagtgt taaagcgcat cgaacaacgt ggatttacaa tcgaaaaatt ggagtttcgt
    35041 tcacaggttt cagaagagtt gattgaccag cactatcagg acttggttgg tcagagtttt
    35101 tacccaccga ttcgtgaatt catgacttca ggtccagttc ttgtgggtgt catttctggt
    35161 cccaaagtaa tcgaaacttg gcggaccatg atgggtgcaa ctcgtccaga agaagcttta
    35221 ccaggcacta ttcgaggtga ttttgcaaaa gctgctggag aaaatgagat tatccaaaat
    35281 gttgtacatg gttcagattc agaagagtca gctaagcgag aaattgctct ttggttttaa
    35341 gagtggattg gctcaatcaa ttggttaaaa gctcatttga atagaaagta tagtcaatta
    35401 gtttaagaca tgacgcatga tatcaaactt tttagttttt gatatggtgc gttttttgat
    35461 taagtgacta ttagtttgtc tcgctccgtt aggtgcgaga caaaaaaaac acccgctatg
    35521 cgggtgtgcg tcgaaggtta taccaaaaaa actccaaacg cgatacaata aaggtgttca
    35581 atccaattgt aaagcgaaag gagaaaaata tggcacaaaa ggttctttta tcctgttctt
    35641 gtttcaattg actatatttc tatacttttt cttcctttct ctgtgaaaat cgcaagtttt
    35701 tcccaccttt tctcaatact gaaacaacat ctttccagaa cttcaataat ttctttttgt
    35761 gttaaatcat tatttaacta aatctttgga ggcaatacgt tttcaaagct acttttttac
    35821 cataggtttt gagccttcaa cacagattac taagccaaaa atgctctaaa tttttgaaat
    35881 tctaacaaat tccactcaac tttatcatca tctttgactt tcacaatatc ttcctcaaaa
    35941 taacatggaa taaagatagt tttcttttaa aacggttgta ggaggaaaat ctctcctaca
    36001 ctattattga ttctgagaga aaattgcaaa atatcatcta ccaaactttc aattattaag
    36061 attttttgca gtttatctga attagaatcg caaggcttct caataatata attgtcgaat
    36121 tttttcattc taacttcctc tccattattt cttcctttat caagaaaaag ttacctcaat
    36181 attaataaag tacaattcta aattaactcc aattcttgat tcatgataat atttcagtaa
    36241 ctcatcgtgc aattaaaaac aaggattttt atttcagatg atccatcgtg aacacttcat
    36301 cagccatctc ccaaattgcc ggattatgtg ttgcgataat gattagccta ttatcatctc
    36361 gaagagatag caaaatctcc ataatcaact gagaggttgc tgggtctatt gaagctgttg
    36421 gctcatctgc cagaataaag ggtggattct ttaagataat ttttgccaag gcaacccgtt
    36481 gcgattctcc gcccgataac tcaaagatgc gcttatctag gtcaagataa accaggccga
    36541 cctgttctaa agcctgcttc tgcctcaacc gctgttccga ccgactcaac ttttgaccaa
    36601 tgagacctag cttaaggttt tcttcaatac tttggttttc aattaagcca aagttctgga
    36661 agaggtagcc caattcgtga cggaaaaaat cacttgattt ataattggcc aagtctttac
    36721 ctcggtaaaa aatcgtccca tcataaggtt ctaatttccc aatcatgttc atcaaggttg
    36781 tttttccgct accacttgaa ccaattaagg catagacttt tccagcctca aatgtcattg
    36841 aaagattcga aaataactct cgttctccaa aagatttact cacctgttta agttcaatca
    36901 tattaacctc ccttcaaaac aagcatggac atcttgtttt ctttctgcat ttggacatgt
    36961 aactgtaaaa gagatagacc agtaaagagt aacaagacta agaaagcaac tcctatctct
    37021 acctgaagaa atacactcgc aacaaatccc agtaaaaaca cacccagttg agcaaagaga
    37081 taagtgcgat ggatttctaa gaacctgaga cctgcaatgc gtttgataaa aatggcacgt
    37141 ctaaattctt caaagtagag cctattcata gtgttaaaca acaagattga agttgcaatc
    37201 ccaagcacag ctcctgctag cattacccaa cgttccctct ggatattatc caataatgtg
    37261 atgtagttgt ggtaacctgt ttgcatttct gagacccaat tttcaatgcc ttgtctctgg
    37321 ataagctcct gggcatcaga caattgatta aagagaacgt agttctgtac tgcgtctatc
    37381 caaaacaaaa tggactgtgg accagttgat tggggtgtta taacaatgat gattggatct
    37441 ttcaaaaact gctggtaaga aataggggtc gtattataca caaaacgatc ctgacctgat
    37501 tctaaataac ctaccgtagc agtcatttgc tgtcgttcat cttgactaga tatgcgactg
    37561 gttaagtcgt cttcaaaaac agatttataa tgttcttcct ctgaacggag gtgttcaggc
    37621 agcaataaga caaactcccc tacatcaagg tgattcatct tttgactcat tttagttgaa
    37681 ctgtaggact tactttttca gagggctcca aattttattt tcatttactt tttttagccc
    37741 ataaaatatt taccatactt ataaaaagta gtaatactcc aactaaactg acttgtaatg
    37801 aattatatgt attttctgaa gtgttaggta aataattttg agagtaccct tctcgggcaa
    37861 tagtaataat attgtgtgtg tttatttgtt taattccaat agta
//
LOCUS       DAVKBK010000018        36843 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVKBK010000018 DAVKBK010000000
VERSION     DAVKBK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36843
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.018"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            178..1407
                     /gene="arcA"
                     /locus_tag="VWX69_000950"
     CDS             178..1407
                     /gene="arcA"
                     /locus_tag="VWX69_000950"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU9192315.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            1465..2481
                     /gene="argF"
                     /locus_tag="VWX69_000951"
     CDS             1465..2481
                     /gene="argF"
                     /locus_tag="VWX69_000951"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU9192316.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            2646..3593
                     /gene="arcC"
                     /locus_tag="VWX69_000952"
     CDS             2646..3593
                     /gene="arcC"
                     /locus_tag="VWX69_000952"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU9192317.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            3804..5315
                     /locus_tag="VWX69_000953"
     CDS             3804..5315
                     /locus_tag="VWX69_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU9192318.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            5337..6668
                     /locus_tag="VWX69_000954"
     CDS             5337..6668
                     /locus_tag="VWX69_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU9192319.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(7073..7363)
                     /locus_tag="VWX69_000955"
     CDS             complement(7073..7363)
                     /locus_tag="VWX69_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192320.1"
                     /translation="MGALGYYEGFVPYVSNQYQNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(7351..7602)
                     /locus_tag="VWX69_000956"
     CDS             complement(7351..7602)
                     /locus_tag="VWX69_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9192321.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            7806..7883
                     /locus_tag="VWX69_000957"
                     /pseudo
     CDS             7806..7883
                     /locus_tag="VWX69_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8001..8885)
                     /locus_tag="VWX69_000958"
     CDS             complement(8001..8885)
                     /locus_tag="VWX69_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9192322.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(9030..10181)
                     /locus_tag="VWX69_000959"
     CDS             complement(9030..10181)
                     /locus_tag="VWX69_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU9192323.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(10327..12093)
                     /locus_tag="VWX69_000960"
     CDS             complement(10327..12093)
                     /locus_tag="VWX69_000960"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU9192324.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(12150..15266)
                     /locus_tag="VWX69_000961"
     CDS             complement(12150..15266)
                     /locus_tag="VWX69_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9192325.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(15276..17570)
                     /locus_tag="VWX69_000962"
     CDS             complement(15276..17570)
                     /locus_tag="VWX69_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9192326.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELCIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(17629..18429)
                     /locus_tag="VWX69_000963"
     CDS             complement(17629..18429)
                     /locus_tag="VWX69_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9192327.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(18426..19199)
                     /locus_tag="VWX69_000964"
     CDS             complement(18426..19199)
                     /locus_tag="VWX69_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9192328.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(19224..19694)
                     /locus_tag="VWX69_000965"
     CDS             complement(19224..19694)
                     /locus_tag="VWX69_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9192329.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(19685..20116)
                     /locus_tag="VWX69_000966"
     CDS             complement(19685..20116)
                     /locus_tag="VWX69_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9192330.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(20109..20549)
                     /locus_tag="VWX69_000967"
     CDS             complement(20109..20549)
                     /locus_tag="VWX69_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU9192331.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(20561..21199)
                     /locus_tag="VWX69_000968"
     CDS             complement(20561..21199)
                     /locus_tag="VWX69_000968"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU9192332.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(21314..22717)
                     /locus_tag="VWX69_000969"
     CDS             complement(21314..22717)
                     /locus_tag="VWX69_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU9192333.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            22893..23666
                     /locus_tag="VWX69_000970"
     CDS             22893..23666
                     /locus_tag="VWX69_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9192334.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(24837..26342)
                     /gene="adcA"
                     /locus_tag="VWX69_000971"
     CDS             complement(24837..26342)
                     /gene="adcA"
                     /locus_tag="VWX69_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU9192335.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYTEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(26352..27158)
                     /locus_tag="VWX69_000972"
     CDS             complement(26352..27158)
                     /locus_tag="VWX69_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9192336.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAVVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(27151..27855)
                     /locus_tag="VWX69_000973"
     CDS             complement(27151..27855)
                     /locus_tag="VWX69_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9192337.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(27855..28295)
                     /gene="adcR"
                     /locus_tag="VWX69_000974"
     CDS             complement(27855..28295)
                     /gene="adcR"
                     /locus_tag="VWX69_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU9192338.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(28450..29718)
                     /gene="dltD"
                     /locus_tag="VWX69_000975"
     CDS             complement(28450..29718)
                     /gene="dltD"
                     /locus_tag="VWX69_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU9192339.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLQQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(29711..29950)
                     /gene="dltC"
                     /locus_tag="VWX69_000976"
     CDS             complement(29711..29950)
                     /gene="dltC"
                     /locus_tag="VWX69_000976"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU9192340.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(29964..31208)
                     /gene="dltB"
                     /locus_tag="VWX69_000977"
     CDS             complement(29964..31208)
                     /gene="dltB"
                     /locus_tag="VWX69_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU9192341.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(31205..32755)
                     /gene="dltA"
                     /locus_tag="VWX69_000978"
     CDS             complement(31205..32755)
                     /gene="dltA"
                     /locus_tag="VWX69_000978"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU9192342.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNAHIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFENLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(32776..32907)
                     /locus_tag="VWX69_000979"
     CDS             complement(32776..32907)
                     /locus_tag="VWX69_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU9192343.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(33221..34399)
                     /locus_tag="VWX69_000980"
     CDS             complement(33221..34399)
                     /locus_tag="VWX69_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9192344.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            complement(34855..36132)
                     /gene="ltrA"
                     /locus_tag="VWX69_000981"
     CDS             complement(34855..36132)
                     /gene="ltrA"
                     /locus_tag="VWX69_000981"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEU9192345.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGISTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVVSEAAAKRMMYSVSRFIEKRLGLKANMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
BASE COUNT        11238 a         7769 c         6362 g        11474 t
ORIGIN      
        1 tatatatgta ttccatccta tgttgtgtat aataacataa aattgtgcta aatatcataa
       61 tttatattat tttccgagaa attatagcca ttgacattac ctaggaattg cgttataaca
      121 tacatgtaag cggtacccaa aatggtgcca agtcaaaatt tttaaggagg aaaatacatg
      181 tcttcacatc caattcaggt cttctcagaa attgggaaac tgaaaaaagt tatgttgcac
      241 cgtccaggca aggagttaga aaacttgttg ccggactatc ttgaaaggct tctttttgat
      301 gatattcctt tcttggaaga tgctcaaaaa gaacatgatg catttgccca agctcttcgc
      361 gatgaaggaa ttgaggttct ctacctagaa caactcgctg ctgaatcatt gacctctcca
      421 gaaatccgcg atcaatttat cgaggaatac ttagacgaag ccaacatccg tgatcgtcaa
      481 actaaggttg ctattcgtga attgcttcac ggcatcaagg acaaccaaga attggttgaa
      541 aaaacaatgg ctgggattca aaaagttgaa ttgccagaaa ttcctgacga agctaaagat
      601 ctaactgact tagttgaatc agattatcca tttgcaattg acccgatgcc aaacctctat
      661 ttcactcgcg acccatttgc aacaattgga aacgccgtat cgcttaacca catgtttgca
      721 gacactcgta accgtgaaac actctacggt aagtatatct tcaaatacca cccaatctat
      781 ggcggaaaag tggatttggt ctacaaccgt gaagaagata cgcgtatcga aggtggagac
      841 gagctagttc tttctaaaga cgtccttgca gtaggtatct ctcaacgtac agacgcagct
      901 tctatcgaaa aacttttggt caacatcttc aagaaaaatg ttggcttcaa gaaagttttg
      961 gcctttgaat ttgctaacaa ccgtaaattc atgcacttgg atactgtctt cactatggta
     1021 gactatgaca agttcactat tcacccagaa atcgaaggcg accttcacgt ttactcagtt
     1081 acttacgaaa acgaaaaact taaaattgtt gaagagaaag gtgacttagc tgaacttctt
     1141 gctcaaaacc ttggtgtaga aaaagttcat ttgattcgtt gcggtggtgg caatatcgta
     1201 gcagctgcgc gtgaacaatg gaacgacggt tctaacactt tgaccatcgc acctggtgtg
     1261 gtagttgttt atgaccgcaa taccgtgacc aataagattt tggaagaata cgggcttcgc
     1321 ttgattaaga ttcgcggaag tgaattggtt cggggccgtg gtggacctcg ttgtatgtct
     1381 atgccatttg aacgtgaaga agtgtaatcg ctgttcggta ttcgtcaata gaaaatgtaa
     1441 aaaatagaaa gaggaaataa taaaatgaca aattcagtat tccaaggacg cagcttctta
     1501 gcagaaaaag actttacccg tgcagagtta gaatacctta ttggtctttc agctcacttg
     1561 aaagatttga aaaaacgcaa tattcaacac cactaccttg ctggcaagaa tatcgctctc
     1621 ctatttgaaa aaacatctac tcgtactcgt gcagccttta caactgcggc tatcgacctt
     1681 ggtgctcacc cagaatacct cggagcaaat gatattcagt tgggtaaaaa agaatctact
     1741 gaagatactg ctaaagtatt gggacgtatg tttgacggga ttgaattccg cggattcagc
     1801 caacgtatgg ttgaagaatt ggcagaattc tcaggcgttc cagtatggaa cggtctaact
     1861 gacgaatggc acccaactca aatgctcgct gactacttga ctgttcaaga aaacttcggt
     1921 cgcttggaag gcttgacatt ggtatactgt ggtgatggac gtaacaatgt tgccaacagc
     1981 ttgctcgtaa caggtgctat ccttggtgtc aatgttcaca tcttctcacc aaaagaactc
     2041 ttcccagaaa aagaaatcgt tgaattggca gaaggatttg ctaaagaaag tggcgcacat
     2101 gttctcatca ctgaagatgc tgatgaagca gttaaagatg cagacgttct ttacacagac
     2161 gtttgggtat caatgggtga agaagacaaa ttcgcagaac gtgtagctct tcttaaacct
     2221 taccaagtca atatggactt agttaaaaaa gcaggcaatg aaaacttgat cttcctacac
     2281 tgcttgccag cattccacga tactcacact gtttatggta aagacgttgc tgaaaaattt
     2341 ggtgtagaag aaatggaagt aacagacgaa gtcttccgca gcaagtacgc tcgccacttc
     2401 gatcaagcag aaaaccgtat gcacactatc aaagctgtta tggctgctac acttggtaac
     2461 ctttatattc ctaaagtata attttagata ataaaccgtc taccaacagc tatgagggct
     2521 gcgactaata gctttagtcc ggtcctcttt tatataatgg taatctatta tttcttataa
     2581 aatatgtgaa aaatcattaa attgaaatct aaacgcattc tattgagtgt gataaaggag
     2641 aatttatggc aaatcgtaaa attgtagtag ctttgggagg aaatgcgatt ctttcttctg
     2701 acccatcagc aaaggctcaa caagaagctt tagttgaaac agctaagcat cttgtaaaat
     2761 tgattaaaaa tggagatgat ctgattatca ctcacggtaa tggacctcaa gttgggaatc
     2821 tcttgctcca acatttggca tcagactctg aaaagaaccc tgccttccca ctcgactcac
     2881 ttgtcgctat gacagaaggt agcatcggtt tctggttgaa aaatgctttg caaaatgctc
     2941 tcttggatga aggcatcgaa aaaaatgttg cctctgttgt aacgcaagtt gtcgtagata
     3001 aaaatgatcc agcttttgtt aacttgagta aaccaatcgg tcctttctat tcagaagaag
     3061 aagcaaaagc agaagccgaa aagagcggag cgactttcaa ggaagatgct ggccgtggct
     3121 ggcgtaaggt cgttgcctca ccaaaacctg ttgacatcaa agaaattgaa accatccgta
     3181 ctcttttaaa taatggtcaa gtcgtcgtag ctgcaggtgg tggcggtatt cccgtcgtca
     3241 aagaaaacaa tggacatttg actggtgtcg aagcggttat tgataaagac ttcgcttccc
     3301 aacgtttggc agaattggtt gatgcagacc tcttcatcgt tttgacaggt gtagattatg
     3361 tatttgttaa ctacaacaag ccaaaccagg aaaaattgga acatgtgaat gttgcccagc
     3421 tggaagaata tatcaaacaa gatcagtttg caccaggtag catgcttcca aaagtagaag
     3481 cagctatcgc ttttgtcaat ggtcgtccag aaggaaaagc agttattact tcccttgaaa
     3541 atctaggcgc cttgattgaa tctgaaagcg gaacaattat tgaaaaagga taagttgttt
     3601 tactaataag atgtattcta tttctagtat ctttatatca aattagaaat tattcttgaa
     3661 aacatgtaca atatttcaaa agatattagt tttttagact ttaatatggt aaaacaaata
     3721 taaatagaaa gcgttttctt aaatgtttat ttaagaaagt agttggtttt ttacactttg
     3781 ttagacatca ggaggaaaaa caaatgagtg aaaaagctaa aaaagggttt aagatgcctt
     3841 catcttacac cgtattattg ataatcattg ctattatggc agtgctaact tggtttatcc
     3901 ctgcgggggc ctttatagaa ggtatttacg aggctcagcc tcaaaatcca caagggattt
     3961 gggatgtcct catggcaccg attcgggcta tgctaggtac tcatccagag gaaggttcgc
     4021 tcattaaaga aacgagcgca gcgattgatg tagccttctt catccttatg gttggtggtt
     4081 tccttggcat tgtcaacaaa actggtgctc ttgacgtagg gattgcctct atcgtgaaga
     4141 agtataaggg ccgcgaaaaa atgttaattt tggtactgat gcctttgttt gccctcggtg
     4201 gtacaactta tggtatgggg gaagaaacaa tggccttcta tccactcctt gtgccagtta
     4261 tgatggccgt tggttttgat agcctgactg gtgttgcaat tattttgctc ggttctcaaa
     4321 tcggctgttt ggcatctact ctgaatccat ttgcgacagg tattgcttca gcgactgcgg
     4381 gagttggtac aggggacggt atcgtacttc gtctgatttt ctgggttacc ttgactgctc
     4441 ttagtacttg gtttgtttac cgttatgcgg ataagattca aaaagatccg actaagtcac
     4501 tggtttatag tactcgcaaa gaagatttga aacactttaa cgtagaagaa tcttcatctg
     4561 tagaatctac acttagcagc aaacaaaaat cagttctctt cttatttgtg ttgacattca
     4621 tcttgatggt attgagcttc attccatgga cagaccttgg cgttaccatt tttgatgact
     4681 ttaatgcttg gttgactggt cttccagtta ttggtaatat tgtcggttca tctacttctg
     4741 cactaggtac ttggtacttc ccagaaggcg ccatgctctt tgcctttatg ggtatcctga
     4801 ttggtgttat ttatggtctt aaagaagata agattatctc ttccttcatg aatggtgctg
     4861 ctgacttgct cagtgttgcc ttgatcgtag cgattgctcg tggtattcaa gttatcatga
     4921 acgacggtat gattaccgat acaatcctca actggggtaa agaaggcttg agcggtctat
     4981 cttcacaagt ctttatcgtt gtaacttata tcttctatct acctatgtca ttcttgatcc
     5041 catcttcatc tggtcttgcc agcgcaacta tgggtatcat ggctccactt ggagaatttg
     5101 taaatgtccg tcctagcttg attatcactg cttaccaatc tgcttcaggt gtcttgaact
     5161 tgattgcacc aacatctggt attgtgatgg gagctcttgc acttggacgt atcaacattg
     5221 gtacttggtg gaaattcatg ggcaaactcg tagtcgctat tattgtagtg accatcgccc
     5281 ttcttctcct tggaaccttc cttccattcc tataaaatag tgagtgaggt gattccatga
     5341 aaatagatat aacaaatcaa gttaaagatg aatttcttat atcattaaaa accttgattt
     5401 cctatccttc agtactcaat gaaggagaaa atggaacacc ttttggacaa gcaatccaag
     5461 atgtcctaga aaaaacttta gagatttgtc gagacatagg tttcactacc tatcttgacc
     5521 ctaaaggtta ttacggatat gcagaaatcg gtcagggagc agagcttctg gccattctct
     5581 gtcatttgga tgttgttcca tcaggtgatg aagcagattg gcagacaccg ccatttgaag
     5641 caactatcaa agacggctgg gtattcggac gtggtgtcca agatgataaa ggcccttcgc
     5701 tcgcagctct ctatgcagta aaaagcttgc tggaccaagg tattcagttc aaaaagcgcg
     5761 tacgctttat ctttggtacc gatgaggaaa ccctctggcg ctgcatggca cgctacaata
     5821 ccatcgaaga acaggccagt atgggctttg cacctgactc atcttttcct ctgacctatg
     5881 ctgaaaaagg gcttctacag gtcaaacttc atggcccggg atcggatcaa ctagagcttg
     5941 aagtaggagg cgcctttaac gttgtaccag acaaggccaa ctaccaaggt ctcctctatg
     6001 aacaggtttg taacggtctc aaagaagctg gttatgatta ccaaaccact gaacaaaccg
     6061 taacggttct cggagtgcca aagcatgcta aggatgctag tcaaggtatc aatgctgtca
     6121 tccgactagc taccattctt gctcctctcc aagaacaccc tgctctcagt tttcttgcaa
     6181 cacaagcagg tcaagacggc acaggaagac aaatctttgg tgatatagca gatgaacctt
     6241 ctggtcacct atcctttaat gtcgcaggtc tcatgatcaa tcatgaacgt tctgaaatcc
     6301 gtattgacat tcggactcct gtcttagctg acaaggaaga actagtagag ttgcttacaa
     6361 gatgtgcaca aaactaccaa ctccgctacg aagagtttga ctatctagcg cctctatacg
     6421 tcgcaaaaga cagtaaactc gttagcacac tgatgcaaat ctaccaagaa aagactggcg
     6481 ataacagtcc tgctatttca tccggtggtg ccacttttgc tcgcaccatg ccaaattgtg
     6541 tagccttcgg cgccttattc ccaggagcga agcagacaga acatcaggca aatgaatgtg
     6601 ccgttctaga agatttgtac cgtgctatgg atatttatgc cgaagccgtc tatcgacttg
     6661 caacttaatc aggcaactgt ttctacaaaa aaaatcgacc gattaatgaa ctgcacccca
     6721 aaagttagac agaataaatc taacttttgg ggtgttttat tatgaaattg agttatgaag
     6781 ataaagttca gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa
     6841 gatttggtgt ggatgtttct ggtctaaagt catctgaatc tttgagatga gctttataaa
     6901 ttgctttttt cagtttttgc actggtattt cgataaactc aaacttttta gccgtggtat
     6961 tgcctgattt tatagtatat tgaaactaga atagtacacc tctacttcta aaacattttt
     7021 agaaatcgat ttgactgtcc tgatcgattt gtcctgttct tatttcattt tactatattt
     7081 gagccacttc gtctttaacg gctttattca taagctcttg taatttttct ttactatcaa
     7141 ttacttctga ttttccgttg taatttattg taataggttt taacttacct aatttctcga
     7201 cacgctcatt aatttgatct tttttgaagg ctgcatatgt ttttcctaag attttttcga
     7261 aaatatattt atcagatagc ggtttgtatt cttcttcagc ttggttttgg tattgatttg
     7321 aaacataagg aacaaatcct tcatagtaac ctaatgctcc cataagttca aaagcttgtt
     7381 ttctaattca aaccattgca actcagattt cagcttttca gataaatcct gctcatccaa
     7441 ataatgactt gaaattagtg ctgaactcgt ttctgtatcc tgtacaggct gagcacccat
     7501 accagcaaaa aataaactcg ttcctagcaa gaccgaacaa gctcctattg catatttcct
     7561 caaagaaaaa cgctgctttc tctcaaattg aaattctttc atcccatctc ccatcattca
     7621 ttattactgt atattttgta tatcagaaat agtttgtatt cacaaatctt tctagttatt
     7681 cccttatcat tcctaattaa gggagataac atacaataat ttttagttaa atgtatatcg
     7741 atgttttttg tttttcttaa taaacgcaat acaaaaagag cctgttgcca agctctttat
     7801 actcaatgaa aatcaaagag caaactagga aactagctac aggttgctca aaacaccgtt
     7861 ttgaggtagt agataagact gacgaagtca gctcaaaaca ctgttttgag gttgcagata
     7921 gaactgacga agtcagtaac atctatacgg caagacgacg ctgacgtagt ttgaagagat
     7981 tttcgaagag tattagtcta ttatttcttc tcagcgcgaa gggctgacaa gatttgtgta
     8041 cggatatcat ccacaccatt tggagtattt ggtaaaaaga tggtttgatt tcctttagag
     8101 gcaaaggtat tcaaggtatc caaatactgg ttggtcaaga ggatagacat gatttgttct
     8161 tctgtcatgc caacattggc ttccttgagt tcggtgatag actctgccaa tccatccaca
     8221 atcgccttac gttgttgggc aatccccaca ccatgaaggc ggtctttttc tgcttcggct
     8281 tcagctgcag tgacaatttt aatcttgtca gcttccgcca attcttgtgc tgcgacccgc
     8341 ttacgttgcg ccgcattgat ttcattcata gattgcttaa cttctgcatc tggttcgacc
     8401 ttggtaatca aggttttcac gataatgtag ccgtaagtgg tcatttcttc tgctacttgg
     8461 tgttgaacct caagggcaat ctcatctttt ttctcaaaca attcatccaa ggttaatttt
     8521 ggaacagaag agcgaagagc atcttcgata taagatttaa tctgagattc tggacgtatg
     8581 agtttatagt aagcatctgt cacgctctgc tcgttgacac ggtactgagt cgctacattc
     8641 atcataacga acacattgtc cttggtctta gtctcaacca caatatcact ttgcaacaag
     8701 cgcaactgaa tccgtgctgc aatcgagtca atcccaaaag gcaagcgaat atgaataccg
     8761 ctattagcaa ccttttggta tttcccaaag cgttcaataa tcgccaccga ctgctgacga
     8821 accacataaa ctgtactcag tgtgactatc accaatagga gcacacaaac aatcagaaaa
     8881 atcatgaaaa atattgccat aatggaacct ccacaagtat ttttctagta ttatagcaca
     8941 tttaaagaag gctgtgccgt ttttactgcg atttttcctg aaatgtcaat aattagaggt
     9001 gaattgtcct attgtcgtcc aatctcttgc taaaataact ctttataaaa ggcaatcgtt
     9061 tcttctaagg ttggcataaa tggatttcct ggtgcgcagg catcaatcaa ggcattctta
     9121 gaaaggtatt caaagtcgaa atctttttct tcaataccaa gttcagtcag tttcttagga
     9181 atacctactg tctcagaaag cttctcaatc tcagcaatcg cataatcggc acattcttga
     9241 tctgatttac cttctacatg aagtcccaag gctttggcaa cattgcggaa agcttctggt
     9301 acacgtttag cattttcacg ttctataact ggtagcaaca tggcacagca cacgccatgt
     9361 ggcaaattat atactgcacc gagttggtga gccattgagt gaacatagcc aagaccagca
     9421 ttattaaagc tcataccacc aaggaagatg gcattgacca taccttcacg cgcttcaata
     9481 tcatgtccat tttctacagc acgaggaaga tattccttga taagctcaat agcaccaata
     9541 gacagtttct tggttacatc ataagcacca ggtgttacca aagcttcaac agcatgagtc
     9601 agagcatcca taccagtagc agcagtcagg cctttaggtt tggaaagcat gagttcaggg
     9661 tcattgacag aaatcaaggc aaggctattc ttgtcaacca ttaccatctt aaccttgcgt
     9721 tcttcatcag taatcacata gttaatggta atttctgctg atgtacctgc cgttgtattg
     9781 atagccacaa ctggcaaacc ttttttagca gacttatgaa gcccttcata atcctgtggt
     9841 tttccaccat ttgtagccat gatagaaata caactagctg catcctgtgg agaacccccg
     9901 ccaagactga tgataaagtc acagccatgt tcttgcaaag cagctacccc atctgtgaca
     9961 tttttacaag tagggtttgg ctctacatcg ctaaagatga catattcgat tccttctgta
    10021 tccagtggtt ttaaagtctt aggtaaaata tcactgcctt cgatgtactt atctgtcacc
    10081 aaaagtgcct ttttatagcc aagttccttg atataaggac ccacttcatt tacaacacct
    10141 tttccaataa ggttgactgc cggaacataa aatatagcca tataattttc ctcctgcgcc
    10201 tccgcgctat ctatttaaca tcattatatt actttttgta ttcgttttca attatttgtg
    10261 aattgtttaa caaatctttt taaaaggata ggagggacgt aagttcacct cctatataaa
    10321 caagttttat ttatgtagtg gtcccaacaa ctgacatgca cgatagtctg ctgattctag
    10381 atcttctgtt ccaaataagg accaattttt aggtctaaag atatcttcct caggtacatt
    10441 atgcatattg acaggaattc tcaacataga agccaaggta atcaagtctg ctccaatgtg
    10501 tccatatgtt atggctccgt gattagctcc ccaattattc atgacgtcat agacagactt
    10561 gaaagcacct tttcctgtca aacgtggagc aaaccaagta gttggccatc ctgaatctgt
    10621 acgattatct aaagtatggt gaacatcttc aggaagttca agtgtgtaac cttctgcaat
    10681 ttgtagcact ggaccaaccc cttttagaag attgagacgt accattgtta ctggcatatc
    10741 ccccttcgtc aagaaacgag ttgagaatcc tcctccacgg aagtactcgc ggtttgctgg
    10801 tgggaagtct gtattttcaa gcatagcctg tacttcactt tcatccaact cccagaatgg
    10861 tttcataaca ggtttgccat ctcgagtagc ttgacctgta ccatccaatg tacaagaacc
    10921 agagttgatt agatgtaaga agccagctgc agcacgaccc tctaaagtat atcctgttac
    10981 acgttcaaca gcctctggac tccaataagt acgcacatca gcaaagattt gtggagtatt
    11041 tgttagtaga taattaaaga gcatagacac accatttagt gaatcattct ctgtcgcaaa
    11101 tacaaatggt tttcgaatac cattccagtc aaactgagta ttgaggaaag tttccataaa
    11161 atctccattt ggaaaatggt ctgtccactg acgttgacct tggaaaccag ctactaaagc
    11221 atggtgacca actgcttctt cctcaaaacc aagttcagca agtcttgggt taccaaccat
    11281 taagtcacgt ccaatcatga acatcttaat aacaaattcc cattgttttt ctttctcttc
    11341 tttagaaaga atcaaatcct cacgatttcg gtcaactcct tctttgatat gttcttttac
    11401 ccaaaccata gcacgttcaa actcttcagg gtcgtaaata ccacggtcca tacggcgtgt
    11461 gaactccgtc atatctaccg attcatttcg cattcctaag tattcttgga agaaatccgg
    11521 atttacaata gaaccaccaa tccccatcga aacactaccc attgataggt aagcagtgtc
    11581 tctcatcaag ccagttgcaa gagctgcacg cgcataacgt aaaagttttt ctttgacatc
    11641 ttctggaata tctgtatcat tagcttcctg aacatctcta ccataaatcc caaaggctgg
    11701 aatccctttt tgagcatgtg aagctagtac agctgcaaga tagacagctc ctgggcgttc
    11761 tgtcccatta aatccccaaa tagcatgagg aatatctgga gacatatcca tagtttcact
    11821 accataacac cagcatggtg taactgtaat tgttgcgcaa acatttgatt ttttaaacaa
    11881 ctcatgggaa gctgcagcct ctggaacacg accaatggta gatggagaaa tcacacattc
    11941 cacaggttcc ccatctggat atttcaatgt gcttgaaatc aaatctgcca cacttttagc
    12001 catgttcatt gtttgtactt caagtgattc gcgtacacct tgacgacgac catcaatagt
    12061 cggacgaata ccaatacgtg gatgttgaat catactattt tcctcttatt tttctgtttc
    12121 tttcatacta ccgatgataa tttttaaaat tacttataag tataaacctc tacctctgcc
    12181 aaacttaaag gaattcctgc gtttctcaaa gaaattctaa ccttttttcc cttcagccct
    12241 tttaagtcta tggatagatt attgctttct aaactgtcaa tatgttgttt aaaaacttca
    12301 tgattatttg aatcatatat aataatatca aaatttgata atctctgaat ttcagcatct
    12361 gttctattat aaataattaa cttttctaat tcttcggttt gtgctaaatc tatctcccac
    12421 catgaaggag aatctccttt ggtatgagtc actgaatgat gaccataatc tccgttttta
    12481 tttccatcaa ctgctagacg agaaaaacca ttgtaatccg ttgaactctg tcgagtttct
    12541 ttggttaatg caatattaga aagtttcttc ggagttctct ttgaaccata gacttcaact
    12601 tccgctaaac ttaacggaat agctgctgat tttaattcta ttttgactag cttagcccct
    12661 acagaaggta cttttaaaga taacaaacca tcaactactt tatcaaaatg tcttctaaaa
    12721 acttcttctc ctgatgaaga tagaaaaata acatcaaaat tagataaacg ctgaggttcg
    12781 gcatctgttc tattataaat atcaacttta gaaaccgtaa actcttctcc cagatcgacc
    12841 tgccaccaag cgttagaatc tgccttagta tgagtcaccg aatgatgtcc gtaatctcca
    12901 tctttattac catcaactgc taaagcagct acaccctcat aattggttga actttgagta
    12961 gctaccttat ttgtagagac tactttatct tctgttattt tatctatatc ctcttcagat
    13021 tgcttaccat ctgattctct aaaaacctct acttctgcta aactcaaagg cactccactc
    13081 gttagtaatt taactttaat ataccttgct cctttttctt tgaaatctag actaacagat
    13141 tcacccgaca aattattaac atgtttctta gcaacttcgt ttctattatt gtcatataga
    13201 atcacatcaa aattagatag acgttgagtc tcagcatctg tgcgattata aattttaaca
    13261 agcccaactt tatccatttt tttcaaatcg acttcccacc aagagggatt atctgcccta
    13321 gtgtgtgtta ccgaaccaga gttaaaatta ccatttctgt taccatccac agctctatta
    13381 gggtctccat tgtaatctac agaactttgt gttgttggtt ttgcatatgc tatattcaaa
    13441 ttaccatcat taaatttatc tggtgttgga aaagggactg ggcctgtccc ttcagtattt
    13501 atagacatct ctaccattcc attatgatta accgtaatgg tataaacatg ggtattctca
    13561 tcccaatttt ctgtataagt ataatgattt ttatcgccac ttatatttat ctgaggttta
    13621 tgaccagtat gcccttttaa tgtaagtgtt gttgtcctaa agtcattatc tacaggattg
    13681 atggaataat ttttgcttat ccagttcgct aactctaatt cttctttctt ccaacttttt
    13741 gatgcatcaa aatttcctga taatgcccac atagctgtct tatctgtcct gtaattgttc
    13801 aataaaatat gtaaattatt tggattttct ttaacaacag cgtaagtatg tggcgtcaaa
    13861 tctaacgata acgactttgt attattagta tacataggca acattacttg ctgattttta
    13921 ttgatattag cattactatt ataaatatac caggaattac ctacacgctg agcataccca
    13981 tctccttcat aaagttttgg ataaagcgag tttaaatagt tgactttact agacaattcc
    14041 tcactatttt tagtcaaaat ttttgcatta gggaatatag atgaaatctt ttccttatca
    14101 attttctcat gtattacagg aagaatatga tatctcccat tattatataa aggcattgtt
    14161 tcatcattcg aataaagtcc ttgataaaat ccgtttaatg aactaatcct accttctcca
    14221 ttccaaaata cagcttttgt tctatttaca acttcttcct tacttggagc tggattttgt
    14281 atagcatgtc taaagaaagg aataatacct ttagtaaatg ctggagttgg tacatcattt
    14341 gtcataaatg tatacgcggc acattcaaaa ttataaactg tgcctccccc agtatataca
    14401 ttcatcattt ccatagcaat cattgattct ggttccgatg cataggatct catatcccta
    14461 gctcttccag tttcaaatgt gtttgtataa tgtttttccc accatttcca tgtatctgtt
    14521 gatgagcccc agttatcaca taagccactc aaccaaaatc cactaacgat agaatctgta
    14581 cccgcatcat ctcttattgg cgtattttta gttgccaaca ccaaattttt atgatatttt
    14641 tgactcgctt caaagaatgt cggatcattc ataatagttt cccagaacca tttttcatga
    14701 tcatgccaga taaaatgcgc tccatatttg gcacaaactt ccaaatattt agcactatgc
    14761 ggagctaact ggttattgta aatccaataa ttctcaatat ttaaaacacc ttttaacaca
    14821 ctatactttt ggaattgttc atctaaccac tctggaggaa ctgtattacg ctctccagcc
    14881 gacataataa ccaagaaaac tggaatgttt agactttgag cttcctccaa catcttgaca
    14941 taccattctc tcaattcttt cgtatctcgt ggaatacaac ttgttggttt acagactttt
    15001 gcaggatgaa gttcaatcgc tgcatatggc tttacatctt caggaatagc ttcccatgct
    15061 cccttcaatg tgttccccca ccataatccg ttaccattat cattgccata caacggagaa
    15121 agcaacaatg gcgattcatt attaatcgtc gttctcattt gaacacgatt atcagcctta
    15181 actcctgcta acaatccaaa acataacatc ccaatacata caaacaatat tgtgattaat
    15241 tttcttttta ttttttcttt attcatgact tatacctaaa aatttaactc aataattttt
    15301 tctgaattaa ataccaattc aatattttgt acatcagtat ttttgccata tattcttact
    15361 cttacttttt gatctttgtt tcctccttcc aattttagga atgttatatc cccatttttc
    15421 caagcaaacg ataccttata tcctcctctt actctgaaac ctttcacttc tccttctgac
    15481 caagcagaag gtaaagctgg aattagtgat aaccaattat gatggctctg tactaataat
    15541 tcacaaattc cactcaccaa acctaaatta ccatcaattt gaaatggtgg atggtcaaga
    15601 aataaattgc caagagtcgc attatttaac aaaccattaa tctggttata agcaggttca
    15661 ccttgatata gtctcgcaaa aaaatgaatc agccatgcag cactccaacc tgtttgtgta
    15721 ctagcatgca aaccacttac taaccaatta ttaatcgctt gctccctatc ctgtgaagat
    15781 aaaaagttag cgtttgataa tctcctattg atagtgattt tagctgcttc tgctaattcc
    15841 ggagttttat gaatatcaat ctcattataa ggataaagcc caaatagagg tgaaatgtgt
    15901 ctatgaccag gctctacttc ttcataatcc tctagccatt cttgtatttg cccattacta
    15961 cctatttttg ttctaggtaa tttctttttt aactccttca cacgactaat aaaatccgaa
    16021 ttgtctccta attgttttgc aatgccaatg catgaatcac aaaaatatct tagaatttga
    16081 ttatcaattg tagatgatag acaagcattt ccttcaatac cattttttaa gcgatattta
    16141 ttttccggtg agacacttgg acctgtcatc aagtagccat ccacctcaaa taaataatct
    16201 tcaaagaaaa gaaatgcttc ttttatcatt tcaaaatgtt ccgtaagaat acgctcatct
    16261 tggaaatata aatagtgttc ccaaatatga gtacataacc atggaatagt taatacccaa
    16321 attgcagccc ccatggcatg agattgggga gccgtatcgc caaaaccatc cgtattatga
    16381 tgtgctgtaa aacctctagc tccatacatt ttcttagcgg ttagtcttcc cggttctctc
    16441 attctttcga gcatatcaaa taatggatat tctacttctg gtaaatcaca tggacctacc
    16501 atccaataat tcatttgagt attaatatta atcgtatatt tagaacccca aattggattt
    16561 aattcatcac accatattcc ttgaagattg gcaggtaaac cattcggttg actagacgat
    16621 attaacagat atcttccata atgaaataac aagttagtca agtagttact atacttttta
    16681 gtgttttcaa gaagtagatt cgttggaatg ctaagacaac ctttactata gtctagttta
    16741 aaatcaactc tattaaattg ctcctgatat ttttttacat gttcatcttt ttctgtaaag
    16801 taatcaatac tactaaattc tccctgaaga gaagaaatat ctatatttcc ccaataatcc
    16861 gtcattgatt tgagataaag aaatacctct gtagcattcc gaataactat tgtctctccc
    16921 aatacactta cttcaccatc cgtaacctta gaatgacata ctactttaaa ctgaacacct
    16981 tttctacctc cagcagaggc cgacattaaa attgtacttg aatccagttt agatacttcg
    17041 tcattaaacc gtttatttct acccaaatta atgtttaaat ttaatgtgtt ttgaactgat
    17101 gacactatac ggcaacataa aatattctta ttaaaactcg taaaatattc tctttttatt
    17161 tgtaaattac aactattagg ctcaaacaca acattagaaa tagctgtatc taaatctagc
    17221 tctctttcat acaatgaaag agcacaagac tgaatatcta tatgctcaat gcaaagttcc
    17281 ccaagtaatt catagtggct ttgatctctt ggggtagcaa acattgttaa ctttatcaat
    17341 tcttcggctt tctgaatttc tccatctaaa agatattccc gaattttttt aagatgcaat
    17401 agtgagtctg gattatttct atctgacttt cctctatacc aaatagtctc atcgtttagt
    17461 tgaatacatt cttttgtagc tgaaccataa atcataccac ctaaatgacc gttcccaatc
    17521 ggcaaggctt cattccaatt tgcggcagct ttcttatacc ataatttcac tctttacctc
    17581 tcttccaaaa tggaggtgat atcccaaata ccacctccac actttctact acttcaaaat
    17641 tcctaaaaca actaggataa ctccaatagc cataacacta aagattagta caaccggatt
    17701 ctttcctttt ctaattaatt tacacattaa taaagtcaaa gccataggga taaatcctgg
    17761 aattaatttt gtaatcattt cttgaacaga aataacaagt tccccctgct taaattctaa
    17821 tccaaaatta ataccaacca ttgatggaat caaaccaccc actagtacta gccctaatgc
    17881 tgtcgccata ctcgtaacgc gattcaatgt tccttttgta ttattttctt ggataagact
    17941 agaaccctta gtatacccat atttcaaacc gaaatattta acaggaatat taataatatt
    18001 aaacaatatt aaggcgataa agatacctaa agcaccgccg tctttagaat aagacgcacc
    18061 aatactaaaa cagataggaa ctagtgtcag ccagaacaaa ctatctccta gaccagccag
    18121 tggccccatc aagccaactt taataccagt aattgaagct gcaccttcat ttccttcttg
    18181 ttcttccata gcggaagtaa ctccaagaat aaatggtgcc gctgtttgat gagtattgaa
    18241 aaactcaagg tgacgtttca ttgcaggaga agctgaatct ttgtctgggt atagtttttt
    18301 caatactgga agaattgtat atagaaaacc taggttctgc attctctcat agttccatga
    18361 agaaccatac ataaaacttc gtttgaaaac ttttttaagt tcaactttag ttactttatt
    18421 attcatcata gatcaagatc ctcctcaaca tcactacttg aagttgtttc ttgtggttta
    18481 cttccaatca tatcgtagaa gtatgctacc gcaataccaa ctagtgagat cccaatggtt
    18541 gacattcctc catacacaga acaaatgaat ccaatcaaca agaataccca catatttttc
    18601 ttgagcatca tatttaaaag cataccaaaa ccaattgaag gtagtaaagc acctgcagag
    18661 ttaagtccct gcataacgat tggtggaacc ttagcaaaca agtctgccac atattcccct
    18721 ccaagcataa tagctaggaa aattggtaca attttaaata aagtgattaa aaccaaactt
    18781 gaataatgat aaaaaccgat ctttgaataa tctccgtttt tagcatcatt atcagctttt
    18841 ttcacaaaat aaacatctaa agtttttgca agaacatcca actgttgagt agcaactgca
    18901 attggaactg ctatagcgat accagcagtt tctccttgac cagacaaaat accaaatgca
    18961 gtaccaataa tcgcacctga aatagtatct ggtggagtgt aacctccaat acctgttaca
    19021 ccgagccaag ttaattcaag agctgaacca ataagaacac cttgggtgaa atctcctaag
    19081 actaagccaa ccattgcact tgtaactaac ggacggtgaa tcataaataa cggtccatta
    19141 tagtcaatag tggcaataat cccaactaat gtcaccagta atgcttgtgt gaatagcata
    19201 tactgtacct ccttaaatta tttttataaa aatttttcca acattgtaac tttatcatta
    19261 ggaaccattt gaatttcaac tctcgttccc ttatcaacta ttttcttaaa ataatatttg
    19321 tcttcttcac ctagagctac acctcccgtt accttttcat tttcctccgt tttactcatc
    19381 tgtcctacat tgaggtactc caattttaaa tttccttcaa tagaatcata cacatctttt
    19441 ggatttgtat atatcagcat tgttctcttt tttattggca cagagtttaa aacttccaca
    19501 aaccgtttta cactaaagaa aacaattttt aaacctaccg gtgcagaaat ctttaaaata
    19561 gattgtcgtg ttttatcttc tgagatgcga tcattaacaa tgataacttg ctcaatatca
    19621 tactttttta gccacgtagt gacaacttga ccatgtacca gacggtcatc aatacgaaca
    19681 aactctatag acataaatcc tcttcctcct ctacgttaag ttgttgttta acattaaaca
    19741 aactattttg agcattttga acaatttctt ctaaattgat ttttgaatca taacttgata
    19801 ttaattccac taggagaggg atattaaacc ctgttacaat atcaactgaa tccaaattta
    19861 aaaaccgtga caaagccaca ttattaggac ttcctccaat caagtcagtc aaaacgataa
    19921 cctcttgatt tgagtctaac agttcattta cttgattttt aaaataatgt tcaaactcta
    19981 caatattctc tccaggcatc aaacctaatg tcctaactct atcatttgtt gtctcaccaa
    20041 caaacatttc tgcggtcatg agagctccgc tagcaaaatt accatgactg gcaactaaaa
    20101 ttcctctatt aaacattttc tctttcaaca actactcctt tcttaaggat aatattagca
    20161 taaagtgaag tttctcctgt agcaacaata gcataagctt tcttactacg ttcataaaag
    20221 tcttctcttc taagataagt aatcgtttta agatctgtac catgaccttc aatcatctgt
    20281 ctataggtac cccatatctt aggaatatca tcacccgaaa caacgttcat aaactgaatt
    20341 gaactatcga cgtaactatc taatggcatt aaatacagaa tggaatctaa taattctgga
    20401 atatttacgc catcacaacg aattagctta tttgcacatg aggcagaagg ataattcgcg
    20461 tcagctaata ctatttcatc tccatgtccc atttccatta aagtcttcaa taaatctgga
    20521 gaaatatttt tcggtatatg ttttaacatt aatatcctcc ctattttctc tgaccgtatg
    20581 ttttaaattt ttctgccatt aaatccatct cctcatcagg aagaactact ggctctccaa
    20641 aattcttagc taaacaataa atttttgcac aatattcaac ttcttcaaca atattaaatg
    20701 cattcaataa attttgtgca cctgctaaaa ttccatgatt cgctagtaaa actgctctac
    20761 gaccttccat tgctttagct gcattcacag ccaattcttt cgtaccatat gttgcatact
    20821 cagctacccg aacatctttc cctgccactg caatcatata atgactagcc ggaagtggtt
    20881 ctctgagaca agctaatact gttgcataag ttgtatgagc atggataatt gcatcgatat
    20941 catcacgagt ttgatattga atcaaatgca tataccattc gctagatggc aagcgttctc
    21001 cctctacaac atttccatta atatccatca ctacaatatc ggattctttg atttcaaaga
    21061 aatcaatacc cgacggggta attgccatca attgtttttc acgatcgaaa acactgagat
    21121 tcccacctgt tcctttcgtc aaatctgttt ctactagctt cttgccatac ttaattaatt
    21181 cttgttttac atctgacatt cttgtcctcc tcatatcaaa acactaaata tttttcaatt
    21241 caccaattat ccccccttct tgtacaaaac ttaagaaggg ggagggaggc aaatttacaa
    21301 actctcaatc tttttaattc ttttgggagt aataactctc taattgtaga aactcctcaa
    21361 taacatggtg agcttcttcc atccctttta attgtcccat agctatgagc tgcacaacaa
    21421 tattccccac agctgtaccc tcagtcgaac ctgtaagaac ctctttacca gttctatcag
    21481 caatcatttg gttaaagtaa ctggctctag cacctcctcc aatcacatat atcctcttat
    21541 aaaccttatg agttagttct tctagtaact ctatcgcttt cctatacgtt tcagctaggc
    21601 tttcataaac aatcttaaat agttgtccat ctgtccactc tctagtttca tgatgataag
    21661 ctagatattc tgtcaaagtc ttgtgcatat cagattctgt tgcaaattca gttgattcag
    21721 tatcaatcag aggaagattt tctttttctt tctccaccat tgtcctaata tcatcaaaag
    21781 aataggcttt ccctcttcgt tcaaatgaac gtcttagttc ctctatgatc cacaaccctg
    21841 tacaattctt cagaaatgta atctctccat ctttaccgac ttcatttgta aatccataac
    21901 tgaaggattc ggtagtaaga atcggtgaag taagttccac tccaaccaaa gaccaagtac
    21961 ctgatgaaat aaataaacta ccttctgtct taggtactga gacaatcgca cttgctgtat
    22021 catgactaca aacattcaca acaggaatat cgcctaaacc atactccttt tttatccttc
    22081 caagaacatt tccctctgaa acaatttcag gaagtaaaga tgaatccaat tcaaatagtt
    22141 ttaagatatt ctgattccaa ttttgactcc taggatcaaa taattgagtt gttgaagcaa
    22201 tgcttttttc tgtagcaaac ttacctgtca agagataatt aaacaaatct ggcattaaaa
    22261 gaatcttatt ggtcttatag aaagagtcag gagattcttg acgtgcctta aagagttgaa
    22321 acaaggtatt tatctccata atctgatttc ctgtctctga atacagtttt tctaattcag
    22381 tcatttcaga tatttccttt aacactccct ttgttctttc atcacgataa tgaacaggtt
    22441 gtgataacag cttaccttca ttatcaatca gtccaaaatc aactccccat gtgtcaatac
    22501 cgatagataa aatcttgtaa ctagtattag ccaagcggat actttcaaga attttagcta
    22561 gtagaaagtc aatatcccaa gataaatgcc cttttactct aataggtaga ttagaaaagc
    22621 gatttatttc ttccattact agtttatttt cagaaaggta accaacgatt gctcttccag
    22681 aagtcgcacc taaatctatt gctaaaaccg cttccatttt tcttctctct tcgtccttga
    22741 ttaactttat tataatcccc acattttatt ttttcaatat gtgaacgctt acttgaataa
    22801 tgttcaaatg ttaacccaat attcataaaa ataattcaaa ttcctccaat ttgtgctata
    22861 atatagttga aatgataaat taggaggagc ttatgataaa agatgaacgt gtacttgaat
    22921 tgattgaaat tattaaaaag aaaaaaagaa ttgccgtaaa agagctggca gaaatcactt
    22981 tctccagcac aagtacctta cgtcgtgatt taattttctt agaaaatcaa ggtcttatca
    23041 aaagaaagca cggatacgtg accctgtcct ctatgaacac aattgaactt tctcatcaaa
    23101 tacgggaagg agaaagtact aggcaaaaaa gactaatcgc tagtctcgct aaagacttta
    23161 ttcggtctgg tatgtgtgtt tatctggatt ccagtactac tgtctacgaa ctttgtccct
    23221 atctttctga acttgataat ttgattattt ttacaaatgg tttacatact gcacaaaccc
    23281 tatctgaaac tgttaaagat agctccaaaa tctttatcac atctggcgag gtcaaacatc
    23341 aatcctgttc cgtggtcaac tatgataagg aaaattcttt attagatcat tttaatatcg
    23401 atttagcatt ttgttcagca agaggtattg atgaccaata tgtttatgaa gcttctctca
    23461 gccaagctat ttcaaaaaag aatattattg acaaagccca tgaaaccatc ttactgattg
    23521 atagttctaa attttacaag actggatttt ttaaaattaa tcccctctcc aaatacacaa
    23581 cctttatttc agacaccgtg ccagatcaaa aattattaga cgcagtcgaa ttatttgatg
    23641 gagaatgggt ttctgatatt caatgaaaat caaataggaa gctagtctca gcttgctcaa
    23701 agtacagatt tgaaaactga taaagtcagc tcgaaacact gttttgaggt tgtagataga
    23761 actgatgaag tcagtcacat atatacggaa agacgaagct gacatgatgt gaagagattt
    23821 tcgaagagta ttcgttctgt ctgctgactg atttacaaat attcaccaca tgacattatt
    23881 ttctcagcaa ccctaaaaac agaggctgga caaaaactca atttcaggag aaaatggagt
    23941 aaaccttccc acaataaaac gcatagtatc aagtttttgc acacctgata ttatgcgttt
    24001 ttctgatttt aaagactttg tcgcctaaac cctatatttc aagaattaag tgaccttgat
    24061 gatctaaatg tattgtggta tactattttt gtcatcggtt accgattacg ttcctatggg
    24121 ttcgtgagag gaggtgaaac taatgagcct tatcatagag ctcgctctta ctattatagc
    24181 ggatgttata gctggaatta tcttgtattt cgtctgcaga tggctagata gtaagaagta
    24241 gaccgagtga ctagcctata aacacccgtt aaatcgctaa gatacgtcaa aaaagccctt
    24301 aactacggcc atagttaggg gctttggtgt tctaatgaac cttatcaatt aactacattt
    24361 tagcatataa tctacaatag ttcaagcatt aagtgaggtt gatgatctaa atttagtgtg
    24421 atataatact tttgtcatcg gttaccgatt acgttcctat gggttcgtga gaggaggtga
    24481 aactaatgag ccttatacca gagcttgctc ttactattat agcagatgtt atagctggaa
    24541 ttatcttgta tttcgtctgc aaatggctag atggtaagaa gtagaccgac tgactagcct
    24601 ataaacaccc attaaatcgc taagatacgt caaaaaagcc cttaactatg gcactagtta
    24661 ggggctttgg tgttctaatg aaccttatac actaactaca ttctagcata taagtccaga
    24721 tatttcaaga gttttattta ttttttcagg ttcccttagt tctgaaaggt ctataatgaa
    24781 gttagccatc tagtatcaaa aaaccgacta gctcttatga actagtcgat ttctcatcaa
    24841 tgcgccaaca tttcttgggc gatttcttgg ccagataggt tatctgggta gtaggttggc
    24901 caattatcca tttcttcaaa tagagcttct tggcttgtac ctccaaaaaa gatatggaaa
    24961 tgttctgcct taactggggc aacattgtgg tcactaaact gaacatattt gaattgtcca
    25021 gcgtcagcat ctgtggcttc aaagaggaaa cgcacgccac gattgccttt cttgtaagtc
    25081 aaaattttct taccgacata cttgtaagtg tatttcttgc tttgtccacc ttgaacaaat
    25141 tccatagtat tatcagtaat gttaatctta gtcacatctg tctgatagcc ttttgtatag
    25201 taagccttgt actcagcctg ggtcatctta ccagtcaact tagccttgta gtcaaagact
    25261 tggtcaaacg tgccgtcttc aaggaaagga taaactgatt gccagttacc tgcatagtca
    25321 ctcaaggtgc ggtccttgac agctgcatcc tcgaagtaac cattttggac tgtcttggta
    25381 tcctctgcct tttcaggttc gattgctggg ccttcttggt ctgttgtttg tttcaaagcc
    25441 ttgaggtttt tctccatcac ggaaatgtag ttttctccag ccttggtgtc ctcttctgtc
    25501 agactttcta aaggattgag gacatcagtt ttgacacctg cttcttttga aagtgtgtta
    25561 gcaagggctt gtgaggcatt ttcttcaaaa tagatatagg cgattttatt tttcttgaca
    25621 tactctgtca attctgccaa gcgagcagct gatggctctg catctggaga aaggcctgag
    25681 attgcgactt gtttgagtcc atagtccaag gcaagatagt taaaggctgc gtgttgagtc
    25741 acaaagctct tttgttttgc ttgagacaag ccttctgtgt aagccttatc caaggcttgc
    25801 aatttttcga tataggcagc tgcattcttc tcaaaggtct cttttttatc aggataatct
    25861 gctgacaagc tgtcgcggat gtgctctact agtttaatgg cacgaactgg tgataaccaa
    25921 acatgggggt caaactcatg gtgatgacct tcttctccat ggtcatggtc tccctcttct
    25981 tcctcgccac ctggcaagag caacatatcg cctgtcgcct tgatggtttt cacttttttc
    26041 ttatccaagg tatctagcaa tttaggtacc catgtttcca tgttttcatt ttcataaacg
    26101 aaggtatctg catcttggat tttggcaact gccttggcag atggttcgta ttcatgaggt
    26161 tctgtcccag caccgattag gagttctaca ttagccgtat ctcctgcgac ttgcttggta
    26221 aattcataga cagggtaaaa ggttgtcacg atattgagtt taccatctgc ctgtttttga
    26281 ttggaacaag ccactaaaaa caaggcacat agactggcta gtaataagct aatttttttc
    26341 acgttcgtct cctatttgat aaaacgtctt actaaactga ttagtataaa gacagttaca
    26401 aaaataatgg taatacttgc acttgcaggt gtttctgcat agtaggaaat gtaaagtcct
    26461 gctaccattc ccaaaaagcc aatcgcactg gcaagcagca taaccgattt aaagtttttc
    26521 cccagacgca gggcaatact agctggcaag accataatgg tcgataccag aagagctcct
    26581 gctgcaggaa tcataagggc aatagccacc cctgtcacca tgttaaaaag aatggacatg
    26641 gtacgaactg gcaagccatc cacaaaggcc gtatcttcgt caaaagttaa gatatacata
    26701 ggacgaagaa agagaaaggt caaaatcaaa acaaccaccg caatgacaaa gagggaaatg
    26761 acctgttctt cactgatagt cacgatcgaa ccaaagagat attggtccaa actcattgaa
    26821 ctcgagcttt tacccttgct catgacaatc agagaaacag ccagacctgt tgacatgagg
    26881 atagctgtcc cgatttccat aaagctcttg taaaccgtac ggagatactc cagaaagacc
    26941 gccgcaatca agacaatggc aatagtagaa acagttggag aaatccccaa aaccagacca
    27001 aaggctacac ctgaaagtga gacgtggcta agggtatcac tcatcaaact ctgacgacgc
    27061 aagatgagga aggttcccaa taccggtgag aaaagactca tagcaataac cgccaaaaag
    27121 gcgcgctgta taaagtcgta agataataaa ctaagcatgg cccacctcct ggccattctc
    27181 atgaacattg aaacaacgcc atggcgagtc ttggttacgg actagatgaa tattgcgatc
    27241 cgcataatcc ttaacttctt cagggtcatg ggtaatcatc aaaacagcct tgccatgatg
    27301 atgggcgctg tggtgcatga gttcgtaaaa ttcattttta cttcctgcat ccatccccgt
    27361 tgtcggctcg tctaggataa acacatcagg gtcagaagca aacatacgcg caattaccgc
    27421 tcgctgcttt tgtcccccag atagagaccc caagcgtttg tctcgatgtt cccacatgcc
    27481 aactgagtcc agactagcct tgatatgctc ctcatcatga gcattcaaac gacggaacca
    27541 gccttttctc ggatagcgac ccgacttgac aaattcatag accgtacttg gaaaaccagc
    27601 attaaaactg gcaatttgtt gaggaagata ggctattctc aatttcttac cttgcgtatt
    27661 tgtctttgaa atagccacct ttccaatgcg tggttgcaga attccaagac tagccttgat
    27721 gagcgtcgtc ttagccgctc cattttcccc agtcaaggta acaaattccc cactatcaac
    27781 acaataattg atatgttcaa gaacaggctc cttatcataa tagaaggaca aatcctctac
    27841 cgtaatatat ctcattattt gatttctcct actaaagcag tcaaaaaccg ctgaatcact
    27901 ttttgttcat ttggagtaaa ctgagtcgcc acttgttcat aggttaaaag tgtatgctca
    27961 tggtgatggt ggtgctcctc agcgattgga cgagccaagt cagtcaactg ataaaaaatc
    28021 acacgcgcat ctttagaatc tttagatgtt tccaacatcc cttccttgac caaagactta
    28081 atggccttgg taactgccgc ctgactgaca ttgagacgac gagccaattc tgaatttgtt
    28141 aaagattcct ctgacaagag cataaggata tgctcctgag tattggtcag ggccacctcg
    28201 ctagtgcaat gacctattag gatttcatgc tgattttccg cctgcaaaat cacctcattc
    28261 aaaaaagcat tgatatcctt tgctagctgt ctcatatctg actcctttcc ttttagactt
    28321 ctctttttta agagaaaaat actattcttt gacattttgt ttaccagtta attatatcac
    28381 aagcaaaaaa agagtcaaga aaaaacgtga aaactagttt cattcttgaa ctcttctata
    28441 ttatattatc tattgaaatt ctttgacatc tccatcataa gtcgcccaat ctttgctgaa
    28501 aaagcgctca ttcagatggt aagtcggagc tggtgtggga ttggatagga aaggatcaac
    28561 tgccttgtca aaagccaacc aacccaacca accaaggtga atggtgtcct tcataaagaa
    28621 aggctccccg ccgtccttag aaaaatctgc tatattggta aaaccttgac tttctaactg
    28681 gtagcgaatc ttctgcaccg tttgttggta catatcctct cgtagaccag catagtccat
    28741 ccatttttta ttaacaggtg gaatgataaa aatcgggttt accttagatt tagaaaactg
    28801 tgttaaaacc aactgcaagt cattatactc tggcgacttg agataggtaa agcttttctg
    28861 agaatccttt aatttcttca aatccttctt gatctgctca ttatagaaat aattttccat
    28921 tcccatctca ttattggaag tatttttttc agcatctgct ttgacaacat cttctattgc
    28981 ttgataagaa aactggtctg gcaagatttt taaatactta gctacatgct tatcgtagtt
    29041 aacatagcct ctaaccgaaa actgaccaaa aaaggaggcc tggcgttcat taaaacgagc
    29101 caataattca atcatttcat tgtctgctgt cgacaattct tctttacttg ccaacttctg
    29161 aaccaggtcc ttcatagcta cgtttgggaa ctgttgcagt aagcgagtcg ctgcatattg
    29221 actagcctga tccccagatt gatgtttcag aaaactagtc aactggtctc cattaaaata
    29281 ctgctggaag gctgctggat catagccatt tttactgaac cactgaggtg agataacata
    29341 cacaacttgt ttattctcca gctgttgtaa catctgttgc attccaaaat attggttaag
    29401 cgatgcagct cccccctgtc ctaaaagata aggacggtag gaacgattgt atttctcagc
    29461 taataccgca ggatgagcac cgtcaaaacg aagccattca ctagagccaa agaagggaac
    29521 aaaacgcaca tttggatcag atagtgctct gactttttga cttcgctcct taaaactatc
    29581 gatagtagta gccactgctg aacgcttttc agctcctaga ttatgatgca tctcagtagg
    29641 ataaaagaaa atgagcagaa aaaccaacaa accagcgatc aagaccggtc cgaagatcat
    29701 ccataagcgt ttaagcattt tgtagctcca caataccagc tataatttta ttagctgtat
    29761 tccagtcgtc acgaccaaac tctgttacag ggacacgaat gtcaaaacgg ttctcaatct
    29821 ccacaatcaa ctcaaccgtt cccatactat ccaagacacc tgcatcaaaa agatcttcat
    29881 ccatcatgtc agaaacatct tccataaaca actcatcaat aatttcgata acttctgatt
    29941 tgatatccat attttatttc cttttatttt ttaaaccata gattattcaa gaatccagaa
    30001 aagattaaga atgacaacat gacaacatgg aaagtgacaa ccatgccaag caactgaatc
    30061 cagcgattct caggtagggc agccttccct gcttttttcc gttccttatt gagcgttttt
    30121 ttcttgcgaa cccaggcatc attgatgacc aaacctagtc catgaaagag tccataggcg
    30181 atatagtacc aggtcacgcc atgccaaaat cccataatca gcatatttac aatgtaggcc
    30241 atgcttgagg ttacattacg atttttaaag actttctttc tggttaacac catcaccatt
    30301 cgcataaaga caaagtcacg gaaccagaag gacagactca tatgccagcg attccaaaac
    30361 tcctttaaat cccttgataa aaagggcttg ttaaagttga tagggctacg gattcccatc
    30421 aagtttgaga tggccaaagc aaacatagaa taacctgcaa agtcaaagaa gagctccaga
    30481 ccaaaagtat acataactgc caaggcatag agattaaaga agccacctga ctgcaaggct
    30541 aaattcttca gaggaggtag taaggtctct cctaaaacat gagctaggat aaacttatac
    30601 aaaaagcccc gcatgatata gcggacagat tcatccagca tatccatcaa ctcatctcgc
    30661 tcaggaatgg tctgataatt ttcattaaat cgcttaaagc gatcgattgg accactcgag
    30721 aaagttggca tgaagagaag gaaacggagg aattcccaga gggtaaaatc cttaatcact
    30781 ccatctctca gctcgatgat aatcccaacc gaacgaaagg tcaggtaaga aattcccaag
    30841 aacccaagca aagactgcgt tccattgata gctggttgca ccttgacaaa gataatcgga
    30901 agtagggaca gaaaactaac taagtagaag acccacttgc catccttgct ttttcgataa
    30961 tgcttgtaga aaagcaggag caatatttcc cagcaaaggt aaatacccaa ggcagctagt
    31021 tgattggtct ttccacccac caacatggtg acaataaaga agagacttac caacacttca
    31081 taccaggcaa agcgtttctt gaaaaagagg cctataaaga tgggcaaggt tgcagcaatc
    31141 acataaacaa aatactgagg attaccatat ggctctaaat gaggaagctg ttgaaaaaac
    31201 tccatcatct cttattcacc tcgttaatca atcctttgat gtcaatcttt ccatttggag
    31261 ttagtggcaa actgtctcgg taaaggaatt tagatggcat catgtaggac atcatgatgt
    31321 ctgtcaggtc ttccttgatg gccttggtaa tatcgatatc tcgctcaaac tgctcacgaa
    31381 caccgtcttt taagatgaca taagccaata gattttgtac cttgtggtcc ttgttatagc
    31441 gcggtactgc gacagcagat tcgataaagc gagacttgtt gaggttttga gagacatctt
    31501 ctaactcaat gcggtaaccg ttgaacttaa tctggaagtc catgcgtccg ccgtagagaa
    31561 gcaagccctc atctgtcatg gttcccacat cgcctgtgtg ataggctggc agattttcaa
    31621 actcaaagaa ggcttctgct gttttttcag gattgttcat ataacctttt gaaacagctg
    31681 gcccagaaac aatgatttct ccctgctcac catttggcag tttatttcct tcctcgtcaa
    31741 tgataaaggt tggagaatca gccttggtat agccgattgg taggcgtttg agagtcgcta
    31801 acatctcgtc tgtcacggca actgctgaca gagctactgt cgcttctgtt gggccgtaag
    31861 cattgatgat atgggcattt gggaaacgct cgcgcagttt ttgagctgtt ttgaccgtca
    31921 attcttcacc atcaaagtag aaatgagtga ttccaggcat tttctcactg ttgaagtatt
    31981 cagacaacat ggccatatct gcaaaggatg gtgttgatgt ccagatagcg attggcaatg
    32041 aaaagatagc cgcaaagagt tgcttaaagt cctgagtgat gactgaagga agagtgaaaa
    32101 gcgtaccacc aagtgccaag gtcggtgccc aatacatgac agacaagtca aaagaataag
    32161 gtggctgtgc cagcatttgc ggacgactcg gtgtcgcaaa ttccttatcc gtaatcatcc
    32221 agtttgtaaa gctgaggaga ttatcatgtg aaatctgcac tcccttaggc ttaccagtcg
    32281 taccagaagt aaagataatg tagtaattat catctccctt gactggatgc gtgatttcat
    32341 agttattccc ttgggcaaag gcttcttgaa cctgagctag atttatcatt ggtgtagaaa
    32401 cctgctccaa gggaaaggct gaaatggcaa taatcaagct tggctctgct acttctaaaa
    32461 tagctgaaac tcgctccaag gccgaatggc tatcaattgg aatgtaggca tgacctgact
    32521 tagtcagcgc tacaaaggtt gccaacattt catattcttg gccaccaaaa acaaccacag
    32581 gagacttctc aggcaagcct agttggtcaa tgactgcagc caaactatcc gaatcagcct
    32641 ttaaatcgcc ataagtgtgt tcctgcccca aaacattata gacaggatag ctaggctgtg
    32701 tctgagcaaa atgctcaatg gtttcaatca tatctgctat tggtttattt gacacaatag
    32761 ggattctcct tcaagttaaa attcattata gataaagctt ccttgaccct gaccaagata
    32821 gctaaagaag taaagcagcc ctagaaagat aagaaaatac aaggctgtcc gaccaagaaa
    32881 gaggtacaat tcttttctct gtttcatcaa gaaaaaccat tcatttctgt aatttttcgc
    32941 taaaataaga gtgattctta ctagcttatt tttctaccat tgtaccactt tatatagtat
    33001 cttttcaatt gtttaccgta tgtttccaat agatttcagc ttattttaag gattatacag
    33061 tttttctatg tatattttca aatagagtga tcctgcttca aaactccatt tcaggagaca
    33121 atgaagtaaa tcttcccata ataaaacaca caatatcaag ttttttcaac acctgatact
    33181 atgcgctttt ctgattttta aagacttttt aaccactctc tcatttaaaa taatctcgtc
    33241 tgatataaat taaaatagct tctatcatca gacaaatggc tgatagccaa aaactgatgc
    33301 taataccaaa actctcagta atatagctca ttagcaaaac aaatactgaa aatgctaatg
    33361 tagaaatcac ttcaagaacg gaatagacat taactaaatg attttcctct actgtttcct
    33421 gaagaaatac actttcagga acttctttta gttgcgataa cataccaact aaagctgaaa
    33481 ataataaaaa catctgtgcg tttggaaaat atagaatagt cagtgtcact attgccatag
    33541 ctacaagagg aaaaagaata ctttcccatt tagcagcaag gaacttttca gatagcctaa
    33601 aagcaattaa gccactaatt ataataccaa tagagtatgc tgtattagaa tatccccagt
    33661 aactttccgt tttatttaat aactccgtta caaaaacaag tataatggaa gaaacccaaa
    33721 tcgtatttga aaaaatttcc aataaatttg ctgatacaaa aagtcttaat ctaggatttc
    33781 tagcaactaa cttccaacct ttgagcaaaa tttcaagatt agtttctgac tctaacacct
    33841 ccacttcagc gttaggaaga aataacatca gaaagctaga aatgatatac aagactaaaa
    33901 tgataaacgt ggtaggtaac agaccaattg ttgcaaacaa gagtccacct aatccccaac
    33961 ctatcaattg aacagcttca ccagtcattg ataaggctga attagcctta cccaaatcgg
    34021 tcgcatagcg tggcacaata gcataggaaa caggtgctgc aaaaccatct agtatggaaa
    34081 ttgcaacaac aaatagatag gtcaccaaag gcgctacgga ttgcattacg gtaaacattc
    34141 ctaccagtat cgccaataat atagtctttc caaattgaga taaagataaa accctattta
    34201 gcgctaacct tttagtaacc aacggaacta aaagactcgc aacaaaagag gatattccta
    34261 ttaagatagg aactagtgat gtggcaatta ctgattttga aataatgtat atgttagcaa
    34321 tgattgttac tctaaagaaa atatctgcta aatttgcaaa taattgagag actaacaact
    34381 tgacaaatga attagacatg tagcgctccc cctttagtta caaactttgg aattaaattt
    34441 gatttttaat attttagcat aaaatagcag aaaacaaaag tgaggttttt tacatgaaaa
    34501 aacaaaaact attgccttta ttattcctaa ttttaggagg aattatgatt atcgttgttg
    34561 gctagtacta agaagttagt tagttagtag aataattaca tcttcaatcg aaaaagagac
    34621 tggaaaaagt cttaaaaatc agaaaaacgc tcaaatcctt tggcgctcta agcttttcta
    34681 atgatagatt tagatagtca aaaaaatatc tgaaaagttc ccaggatcgt cgtctcagca
    34741 tcaaaaatac gtgaaatttg cataattaaa ataaatttca ggggagttaa tcgagtaggg
    34801 gataatctct agcccctctc acaccaccgt acgtgccgtt cggcatacag cggttcaact
    34861 aacttttaac gcatgtcgtt caaggtaata atccaaacac gaaaccagtc cacgtttttc
    34921 caggactggt tttgatatag cacgtttaag taccgacttc tgagctacta attgataatg
    34981 gtcgccccag ccagatacct tatctgctat ccatttagga acccctaact taagcaatcc
    35041 ccataatcgt ctcgatttct tcttccattg cttccagata atcactcgta ggcgagtacg
    35101 caagcgctca tctatgctgg cgactatact tttcatattt cccaatgaga aatagtttat
    35161 ccatcctcga atagacaaat tcagttgctc aatacgtctt gttaggtcta tactccattt
    35221 cctctgtgtt agtttcttca atttaagctt aaatctccga acactatctt gatgtggacg
    35281 acttttccaa ccatctgatg atttccagaa cccaaaacct agatatttca actctcttgg
    35341 tctggtaatc ttagtcttgg tcatgtttgc tttcaaacct agccgttttt caataaaacg
    35401 actgactgaa tacatcatac gcttagcggc tgcctcgctt acgaccgtaa tcacacaatc
    35461 atctgcgtag cgcacaaatc gaagtcccct cttttctaat tccttgtcca attcattaag
    35521 catgatattg gataagagag gagataaatt tcctccctgt ggtgtaccaa ctagtgtttt
    35581 ataacgttga ccattaatga taacacctga atgaagatac ttacgaatca aggattccgt
    35641 atctccgtct tcgataatgt tatgtactaa ggacatcaat ctatcttgag gaactgtatc
    35701 gaaaaatttc tctaggtcta tatccactat ccactcatag ccgtcattta agtattctaa
    35761 gagcttcatg atggcttttt cacatgacct atttggtctg aaaccataac tcgtatctga
    35821 gaaatggggt tcacaaatgg ggctcatgac ttggacaatg gcctgttgaa tcattctatc
    35881 cataactgtt gagattccta gttgacggat gcctccgtct ggtttaggta tctcaacttt
    35941 aagaactggt tgaggcttat attttctctg ttttatcagt tccttagtca agcgccagtt
    36001 ttgtctgaga taattatcca tctcttcgat agtcattcca tcaatcccag ctgagccttt
    36061 attggatttt acttgattgt aggcttccag catattttcg cgtgataata tcttatctag
    36121 cagttttgac atgtgcgtat tcctttcttg ttttggtgcc tgagggacat cttatattgg
    36181 tgaaccttca tctagtcatt acgtgtcaaa gtccagttct atcagaccac tcattttaca
    36241 gacacaagtg aagtaggatt acttcgatct gtcgttttct ctttctagcg acagacctca
    36301 aacagtctct ccccagactg tttgagtatt caccccttcg ctccacttcc actacagaag
    36361 tttcctcact actatgggct cggctgactt ctcatgattc gttgttacta cgctttcagc
    36421 gctcatgaaa cctcacggga taagtcgtac atctttcctc gtttatacaa gatatgagga
    36481 cgttaaaagg ttacagtgaa aataggaaat ctgacgcaga gtctttagac tctagaaaga
    36541 tttatctttt tcacacaaac cttagtccga attcaattac tctcgtgatt tacacatata
    36601 ggttacgact acctttttgg actttagagt ttgaagcctc cttatccgct atatacgcct
    36661 tactatcacg ttcctgttcg tagagccacg atttcgctat cccttcctct gacgattctt
    36721 atttcctgcg tcagacttaa aacggtctat ccccagaccg ttttaatccg ctacctcacg
    36781 atagtcaggc ttgggaatcg ctattgggtt caccggtagc aggtgcccac cgaggactta
    36841 cac
//
LOCUS       DAVKBK010000019        33619 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVKBK010000019 DAVKBK010000000
VERSION     DAVKBK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.019"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(68..418)
                     /gene="tnpB"
                     /locus_tag="VWX69_000982"
     CDS             complement(68..418)
                     /gene="tnpB"
                     /locus_tag="VWX69_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9192346.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(399..584)
                     /locus_tag="VWX69_000983"
                     /pseudo
     CDS             complement(399..584)
                     /locus_tag="VWX69_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(888..2450)
                     /gene="guaA"
                     /locus_tag="VWX69_000984"
     CDS             complement(888..2450)
                     /gene="guaA"
                     /locus_tag="VWX69_000984"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU9192347.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CLYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2592..3290
                     /locus_tag="VWX69_000985"
     CDS             2592..3290
                     /locus_tag="VWX69_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9192348.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3333..4229)
                     /locus_tag="VWX69_000986"
     CDS             complement(3333..4229)
                     /locus_tag="VWX69_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU9192349.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(4238..5173)
                     /locus_tag="VWX69_000987"
     CDS             complement(4238..5173)
                     /locus_tag="VWX69_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU9192350.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5170..5895)
                     /locus_tag="VWX69_000988"
     CDS             complement(5170..5895)
                     /locus_tag="VWX69_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU9192351.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(5979..6614)
                     /locus_tag="VWX69_000989"
     CDS             complement(5979..6614)
                     /locus_tag="VWX69_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU9192352.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(6616..7443)
                     /locus_tag="VWX69_000990"
     CDS             complement(6616..7443)
                     /locus_tag="VWX69_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9192353.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7465..7800)
                     /locus_tag="VWX69_000991"
     CDS             complement(7465..7800)
                     /locus_tag="VWX69_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEU9192354.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7801..8517)
                     /locus_tag="VWX69_000992"
     CDS             complement(7801..8517)
                     /locus_tag="VWX69_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEU9192355.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRAQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            9030..9641
                     /locus_tag="VWX69_000993"
     CDS             9030..9641
                     /locus_tag="VWX69_000993"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9192356.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9686..10414
                     /gene="rlmB"
                     /locus_tag="VWX69_000994"
     CDS             9686..10414
                     /gene="rlmB"
                     /locus_tag="VWX69_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU9192357.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10453..11364)
                     /gene="trxB"
                     /locus_tag="VWX69_000995"
     CDS             complement(10453..11364)
                     /gene="trxB"
                     /locus_tag="VWX69_000995"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU9192358.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11430..11654)
                     /locus_tag="VWX69_000996"
     CDS             complement(11430..11654)
                     /locus_tag="VWX69_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU9192359.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11732..12475)
                     /locus_tag="VWX69_000997"
     CDS             complement(11732..12475)
                     /locus_tag="VWX69_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9192360.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12475..13275)
                     /locus_tag="VWX69_000998"
     CDS             complement(12475..13275)
                     /locus_tag="VWX69_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9192361.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13433..13789)
                     /locus_tag="VWX69_000999"
     CDS             complement(13433..13789)
                     /locus_tag="VWX69_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU9192362.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13802..14314)
                     /locus_tag="VWX69_001000"
     CDS             complement(13802..14314)
                     /locus_tag="VWX69_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU9192363.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(14314..14808)
                     /locus_tag="VWX69_001001"
     CDS             complement(14314..14808)
                     /locus_tag="VWX69_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192364.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14943..15389
                     /locus_tag="VWX69_001002"
     CDS             14943..15389
                     /locus_tag="VWX69_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU9192365.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15386..16033
                     /locus_tag="VWX69_001003"
     CDS             15386..16033
                     /locus_tag="VWX69_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU9192366.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(16054..16635)
                     /gene="pdxT"
                     /locus_tag="VWX69_001004"
     CDS             complement(16054..16635)
                     /gene="pdxT"
                     /locus_tag="VWX69_001004"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU9192367.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16636..17511)
                     /gene="pdxS"
                     /locus_tag="VWX69_001005"
     CDS             complement(16636..17511)
                     /gene="pdxS"
                     /locus_tag="VWX69_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU9192368.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17663..19042)
                     /locus_tag="VWX69_001006"
     CDS             complement(17663..19042)
                     /locus_tag="VWX69_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU9192369.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19336..20259
                     /locus_tag="VWX69_001007"
     CDS             19336..20259
                     /locus_tag="VWX69_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU9192370.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20319..20924
                     /locus_tag="VWX69_001008"
     CDS             20319..20924
                     /locus_tag="VWX69_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9192371.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20943..22187
                     /locus_tag="VWX69_001009"
     CDS             20943..22187
                     /locus_tag="VWX69_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9192372.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSS
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22410..22667)
                     /locus_tag="VWX69_001010"
     CDS             complement(22410..22667)
                     /locus_tag="VWX69_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU9192373.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22709..24745)
                     /locus_tag="VWX69_001011"
     CDS             complement(22709..24745)
                     /locus_tag="VWX69_001011"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU9192374.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGQETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKASLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(25005..25922)
                     /gene="glyQ"
                     /locus_tag="VWX69_001012"
     CDS             complement(25005..25922)
                     /gene="glyQ"
                     /locus_tag="VWX69_001012"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU9192375.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(25941..26702)
                     /locus_tag="VWX69_001013"
     CDS             complement(25941..26702)
                     /locus_tag="VWX69_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9192376.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26975..27817)
                     /locus_tag="VWX69_001014"
     CDS             complement(26975..27817)
                     /locus_tag="VWX69_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU9192377.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLESLKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTTAVQSGAPRVD
                     DVDF"
     gene            complement(27932..29323)
                     /locus_tag="VWX69_001015"
     CDS             complement(27932..29323)
                     /locus_tag="VWX69_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU9192378.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29558..29935)
                     /locus_tag="VWX69_001016"
     CDS             complement(29558..29935)
                     /locus_tag="VWX69_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9192379.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            30150..31127
                     /locus_tag="VWX69_001017"
     CDS             30150..31127
                     /locus_tag="VWX69_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9192380.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            31124..32206
                     /locus_tag="VWX69_001018"
     CDS             31124..32206
                     /locus_tag="VWX69_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9192381.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTINLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(32270..33300)
                     /locus_tag="VWX69_001019"
                     /pseudo
     CDS             complement(32270..33300)
                     /locus_tag="VWX69_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10001 a         7484 c         6022 g        10112 t
ORIGIN      
        1 ttgactttcc tgatagagat gttcatatct tatttcaatt cactatacta aaaagaaagt
       61 cctcatttca atagaaatca cgactttctg ataaatttat tttgggagtg atagaaaagc
      121 ccttcataag ccaatctact tgttcaggtg tgagagcttt gacatccttt tctgtactgg
      181 gccaagtcag tctgccgttc tcaaagcgtt tatatagtag ccaaaatcct tgaccatccc
      241 agtaaagggc tttaaagcgg tctttacgtc caccacaaaa gagaaaaact tgaccggaga
      301 aaggatccaa ttcaaagtgg gttttaacca gataagccag tgaatcgatt ccttgtctca
      361 tatcagtctt cccacacacg agatagacct gccctaggct agatagatga attgtcatag
      421 agcaacacct tatccaaaag ctgttctacc atttcgagat tgagagattg aaaaaaactt
      481 acttcaagct tgccaatacg aatttaaagc agaatatcat ttctcttttt agaatcaaaa
      541 ggacgagatt gtggaatctc tacaggaaca ataggttgtg gcattaaaat atcctccaat
      601 agttttactt tactaatagt atacaggagg aactccatga atgatagata ccttgttatg
      661 acgcgcttac tatattagaa agttggctct ctaattaaat taattctcat tatatatatc
      721 aaaagaccgc agtttgaaaa ctacggtcta attttttgtc caaatgtaaa tcacttggaa
      781 ctattattca atttattctt tttagtaaat gttcccgttt taatcccagt tacagttttt
      841 aatcctctgt aaccgttgat tttacaaagc ttttaatttt tttgcgatta ctcccactca
      901 actgttgcag gtggtttact tgtaatatcg tagacgatac ggttaacatg atccacttca
      961 tttacgatac gtactgagat tttttgaagt acttcccatg gaattttggc aaaatcagca
     1021 gtcataccat cgatagaagt gatagcacgg attgcaatcg tgtagtcata cgtacgaccg
     1081 tcacccataa caccgactga acgaacgcct gtgttaacag tgaagtattg ccaaatatcg
     1141 cggtcaagtc cagctttagc gatttcttca cgaagaatag cgtctgattc acgaacggtt
     1201 tcaagtttct cttcagtgat ttcacccatg acacggatag caagtcctgg tcctgggaat
     1261 ggttggcgcc atacgatatg gtctggcata ccaagctctg taccaagagc acgaacttca
     1321 tccttgtaaa gagtattgag tggttcaatc aattcaaact gcatatcttc tggaagacca
     1381 cctacgttgt ggtgtgactt gatagtttga gctgtatccg taccagactc gataacatct
     1441 gtatataaag taccttgagc aaggaatttc acatctttga gcttgcttgc ttcgtcatcg
     1501 aatacataga caaactcgtt accgatgatt ttacgttttt gttcaggatc agaaacgcca
     1561 gcaagtttgt caaggaaacg tttagcagcg tctgctttga cgatattcaa accaaactta
     1621 ccaccgagca tgtccataac ttgatcagct tcgcctttac gaagaagacc gtggtctacg
     1681 aagatacaga tcaattgatc gccaatcgct ttttggagaa gaaccccaac gacagatgag
     1741 tcaacaccac ctgatagacc aagaaggaca cgtttatcac cgacggtttc acgaattttt
     1801 ttgatctgca tgtcaatgaa attatccatt gaccagtcac ctttagcctt acaaatgtta
     1861 agggcaaagt tacgaaggat atcatttccg tatacagaat gacgaacttc tgggtggaat
     1921 tggataccgt aaatgtgttt atctgggttt tcgatggctg cgtataggca gtcagctgat
     1981 gtacctgtac gaacaaagtc agcaggaatc tcagtaaccg catcaccatg gctcatcaaa
     2041 acagtctgtt catcaggtgt tgattcaaaa agcgctgatg gtgtgtgagt tagggttgat
     2101 tgaccgtatt cacgatttcc agcatcacct gcaggaacaa cttttcctcc aagtttatgg
     2161 gtcaataact gcataccata acagattccc aaaattggaa ttccgagttc gaagatttct
     2221 gggtcaatat caaatgaacc atcttcatat acagaatttg gaccacctga tagaataatt
     2281 cctacaggat tgacttcacg aacttcagca gctgaaattt tatggctttt tagttctgaa
     2341 aaaacaccaa tctcacggat acggcgtgaa atcagctggt tgtactggct accatagtcc
     2401 aatacgatga ttttttctac atcttgcaaa tcagttgaaa tgttgctcat ctttttcctt
     2461 tctcaaaaga aatatctttt ctcaatattc tatcacaaat aagggcgaat taccaactaa
     2521 acaaggcgaa gtttgacttt ttctagttta ttggggtaca atagagaaaa gatagaaatg
     2581 aagtgaaaaa tatgctacct gcttatatga aaatccatga tcagataaaa aaggatattg
     2641 acgagcaccg ttgggctatt ggtgagaggc ttcccagtga aagagattta gctgagcagt
     2701 ttgcggtcag tcgcatgacc ctccgccaag ccgtatctct attagtcgaa gaaggcgtct
     2761 tagagcgccg tgtaggaagc ggcacctttg tttccagtac tcgagtacaa gaaaagatgc
     2821 gagggacaac cagttttact gaaattgtca aatcccaagg taaagttccc tctagccagc
     2881 tcatttccta caaaaaaacc attcccaatg agcaagaagt tgccaagcta ggaatttttc
     2941 caacggacaa tattatccga atggagcggg tccgctatgc cgaccaagtt cccctagttt
     3001 atgaagttgc ttctattcct gaaaaattca ttaaggactt taaaaaagaa gaaatcacca
     3061 gtcatttctt ccaaaccttg caaaaacatg gctatcgtat cggcaaatct caacagacca
     3121 tctatgctcg ccttgctaaa gaaaagattg cccactattt ggaagttgaa aaaggacatg
     3181 ctattcttgg attgacccag gtttcctacc tagaagatgg tactgctttt gaatacgtaa
     3241 aaagtcaata tgtaggcgaa cgctttgaat tttatcttga aaataattag attaccacgc
     3301 aaaaactctc tgtcacggac aaagagtctt ttttattttt ctaagaataa atctttcaaa
     3361 gaaatcaaag ttacagcaaa caatatcatt gccataccaa taaaatcaat gggataaaat
     3421 tgttcattca ttattaagaa ggcaaagaaa accgccgata ttggctcaat tgaagccaac
     3481 aagcttgact tgaccggtcc tatcagactg gctcctttaa ggaaagctgt ataggcaaag
     3541 acagtcccga taaggataat gcctgcaaac gcaaggagaa aatcaagact agtcgggata
     3601 tcggcctgta gaacccctgt aaaaggaagg gcgaccaaac ctgctatgac catccccaca
     3661 ccaatgacca agctgctccc ccacttttta atcaaggcta tgggtaaaat gatatacaaa
     3721 gcataagtca aggcagaaaa gagaccccag aacaggccag caggtgtcat ggataactgg
     3781 tccaactgcc catgtgttgc gatcaggaag gttcctccga tggcgaatat gatggaaact
     3841 atctctccca gtgtcggtgc caccctatcc ttgatacagc tataaattaa aattccgaca
     3901 ggacaaacat actgaagcac cgtcgctgtt cccgcattgg tctcctgaat agcagacaga
     3961 taggcgaatt ggttgagaaa aagaccaatc agagcaaaaa taagaagaga cagcaaactc
     4021 tttctatcct ttaaaaagac cagtatttta tcctttgcag tagcataagc caagagcatg
     4081 agaattccac cagcgattaa aagacgcaag ttggtcaaga ccagagccga aattccgtgt
     4141 gccattaggt attggccact cgttcctgac aacccccaag caataccagc cacaactgtt
     4201 agtaaagtcc cttttaaact atttgacatg tctctcctta ctcttctttg cgaatcaagt
     4261 tcatcacttg attgcggtct aatatccatt gagctctctc gtccttttca taggtacgat
     4321 tcgataggaa aatagtggct tcttgcttct gacgattcca catgataaag gtacctgtat
     4381 agcccgtatg gtctagccaa tctccttcca aattccatgc taaagaacgt tccttgtcat
     4441 ccaaaggaga aaaattttga tttaagtctc ttgcaaaatc atctgctaaa tagtgttcta
     4501 aaaagatttg taaatccttt atagtcgaaa ataaaccagc actcccagca tgtctaccca
     4561 ggagacgagc cttgggatca tgcactatgc ctgcctctac acctctaact gttggaacag
     4621 caagctcaac tggcccaaac ttggtttccg tcattcccca aggtttccag acttgatcct
     4681 ttaaaatcac atccaaatct tgattaaaaa ttctttccaa aataaagccc aacagcaaaa
     4741 aatggacatc cgaataaaga aaggctggct gacttcgtct gttgagatga aacatcgctt
     4801 cctttaattc aggggctgtt aaaagatcac gattaggaat aaaaggatca aggtctgttg
     4861 catgagtcaa gagctggcga atagtgatgt ctggataatc actctcaggt aaaaaatcta
     4921 ttaccagtct atcaatatct aattgaccta tttcccacaa gaaggtacaa actgtgccaa
     4981 ccccaacaac cttgctgaca ctagctaggt cataaactag tcctgcctca gtctgcaagc
     5041 catgctctgg gtcactctgg cctaaataga actctgtcca ttgattgtcc ttaaaatacg
     5101 caaaagaggc tccgggataa attcctgcct cgatttgttc ttctattttt ttaataatct
     5161 tggtccactt catacttctt caaaccacaa ttcaacatta tttctatctt tacaaaggaa
     5221 gaatttttca gacttaggaa taaaatattc agtagactca aacttctggc gaagacttgc
     5281 tatgtctaat tcattgacca agaacttgag catagataag tcccaggtaa ccgtattgtc
     5341 cacagtcaaa tcctgcccct gagctggaat aaaatcaagg gatgccccaa tttcagatga
     5401 ttccaagaaa ctttcgatat cagttgggag atgtaattcc atagaaatct caaatttact
     5461 taaagaaatt gatgccaaat ctgtttgaaa ttcaggcttt tctcctactt ctactagact
     5521 tgctatgtca tcttccgcat gaatcaaaat caaatcatct tctggtgaga aaatttcaaa
     5581 agcgtagcca ttttgacctt tatataatcg atgaatcgaa tctgttttag ataagattcc
     5641 ttcaatttct aagggatttt ccaccttgac aatcaatcta gctagttttt ttcttccctc
     5701 taccttacga gtacgcatac tgggagcttc ttctaaaacc agcttttcaa gacccgtttg
     5761 gtcacctagt gacagaaagg ccgattcttc taacaaggcc ttcattccaa gggtttcaat
     5821 ataaaatgtt tcatttaatt ttctattatt agcttttaaa gtaggaataa tccgtacaat
     5881 ctgatttaca ttcataaatt cctccgtcac tttttatttt aaaggatttt agaatttttt
     5941 acaagatatt atgctcaaat ttaacattat ttagctattt agtaaagata gtctttcaag
     6001 gattttgaca aagcctgata accagcaata ctgaggtgca gtccatcagt tgtatattct
     6061 tttttgagtt ggcctgcttg gtctgtcaaa caatcaaata ctggcacaaa ttccacctgc
     6121 atataggcag atgcaagctc ttgataggct tgattccagt tctgaatttt ttcattcgag
     6181 cggatataga ctgcctgctg gtactcctct ctctcattga caggcaaaat ggaaagcaat
     6241 ttaatctctg tcaatggata atcgcgagca acggattgaa tgatagcttc gagattattg
     6301 agagcctcat tcacaggaac atcctttccg atatcatttg tcccaatcag aagaaaaatt
     6361 ttatctactg ctccaccata tagatgagca tcaaggttct ctagtaacag tcctgtctga
     6421 tagccacgaa ttcctcgatt gacaatcgtc tttgaagtcc caaatagctc ctgtagagga
     6481 taatactcga caatggaatc cccaataaaa agaatgtttg gttctacaac agaaatgtga
     6541 tttaggtgac gatacttagt ttgaattttt tcttgttcct ttaggagcca attttctaat
     6601 aactgtactg ccacttcatt ctcctttttc taaccagttt tccaagactt gataaactcc
     6661 tccttggctg ttggctggtg ctagagcagt cgccacagct ttggctttct catcagcatt
     6721 ttccatcgca taggcaattc cagccatttc aagcatttca acatcatttt cactatcacc
     6781 aaaagccatg atttcttggg atttcaagtc ccagcgcttg agtaattcct ccaagcccca
     6841 tgctttatga atcccagctt ggaggatatc aatgcaacca tagccactgg atacagctcg
     6901 gacacggcca tcaaagagag cattgatttc ttccaaaacc gaactcaaac gttcctcacc
     6961 aacaaccatg ctcatcttga gcacaccacc aaagaggtca gatgttaatt catccacaaa
     7021 ttgcatccgt tggtagaatt tttcaatcat ttctggagtc ataaaacttt caagatctgt
     7081 aaaaatcgta ccttccttga caaaatcacc cttcatcccc gttacaacaa actggtcctg
     7141 acacgctcga cccttgaaat gagtcaaagc cttgttgaca atggcgtcat cccatgtctg
     7201 agcctgaatc aattcattgt tttcaaaaat acgagcgcca ttagcaacaa ccagaaccac
     7261 tcgatccacc aagggactca gtagttgtct catgcggtga atttcattgc ccgtcgcaat
     7321 gacaaaacga atgccccttt gatccaactg atctaaaatc ttttccaatc gtgggagatc
     7381 aagctgacct ctagcatcca gcaaggtccc atccatatct gtcgcaatta ccttaatcat
     7441 catttacttt cctctggatt caagctaata ccacttcaat cccacatgtt cattcatttc
     7501 tttataggct gtatcaattc gttccttagt cgcttcatct aactggtcac gatgactgcc
     7561 atcctctata aaatcttcca aaatataagt ttggtaatga tacaagggat atccttctgg
     7621 tgaaaaggtt ccctttggtg ttcgattgac ccaagtagga tgagctttag ctgttccgat
     7681 agttgttttt ccatccttct tcttgatggt gacatccatg agaacaccac gttcagtcca
     7741 cttagcattc tcttcatctc ccatagattc aattcgttga ttggaaatga agttccccat
     7801 ttaatagaca atgagctttt tatctccatc tttttccacc gtttcagatg gttcaacaac
     7861 gtgaggatgc cctccaaaga taatatccgc tccccaatca atcatcttgt gataaagagc
     7921 tttttgttct tcagttggtt ccaatcgata ctcaacaccc atctgaggca tgataatggt
     7981 gatatctgct tccttctctg cccgttcaac ttcagccttt atcttatctt cgtttaaatc
     8041 tgaaagataa cgattatagt cttcctgaga aatatactgc tcaattccat tgaaaccata
     8101 ggaataggct aacaatgcaa ccttgatagc attcacttcc ttaatgacca gcggagcctg
     8161 agcacgtggt tcgtgcgtat aaactccgat tggagtgatt ccagctttct caataatatc
     8221 ggccattgaa ataactccct caatttgcga atccaaaata tgattatgag ctaaatccag
     8281 cacatgataa cctgcctcct taatagcatc cataacttca acaggagcat taaagagaag
     8341 ataacccgct aaataatgat ccttattaat ggttccttca aaatcaccaa tagctaaatc
     8401 tgcttgcttg agccaaggag tcacatactc aaaattttca tgaaagtcat aggtaccgtc
     8461 ttctttttta gctgaaaaga aaagtccatc gtggtagagc aaatccccgt gggccataat
     8521 tctggcagtt ttttcctctt cctactcctg agacttttgc ttagtcccct cttgagaaat
     8581 agtatctcgt ttttgactag tcaagggatt ccttggaagc tttcaaacaa caagaccaag
     8641 cccattgata aaccaactgc tagcaagagt atcgccacaa atcccttatt gctccacttg
     8701 cgataactcc taaaaagttt accaagccct tcataaaacg aaaagctgaa ccaccctgat
     8761 ttcgattttg tcttctttgt atcttcgttc tccctacttt cttatgcaag ccttttcttt
     8821 ttattatatc acagataagt atttctttca caattgaatt gaacttccta tctattttct
     8881 ataaatccta aatgccataa tgctttcaat tcttgtcatt ttgtgatatc atgtagagga
     8941 aatgaactaa tccacagtgg cttattccaa gtataccact tgggctttgg cagtagctaa
     9001 ctgcactaaa cataatataa ggagagaaaa tgtctgcaat agaacgtatt acaaaagctg
     9061 ctcacttaat tgatatgaac gatattatcc gtgaagggaa tcctactcta cgcacggttg
     9121 ctgaggaagt cactttcccc ctatctgacc aggaaatcat cctaggcgaa aagatgatgc
     9181 aattccttaa acattcccaa gatcctgtca tggctgaaaa aatgggactc cgcggtggtg
     9241 ttggactggc tgctccccag ttagatatct caaaacgcat tatcgctgtt ttggtaccta
     9301 atattgttga agaaggcgaa actccacagg aagcctacga tttggaagcc attatgtaca
     9361 atccaaaaat cgtctctcac tctgttcaag atgctgctct tggcgaagga gaaggttgcc
     9421 tgtctgttga ccgtaacgtg cctggctatg ttgttcgcca tgcccgcgtt actgttgact
     9481 actttgacaa agatggagaa aaacaccgta tcaaactcaa aggctacaac tccattgttg
     9541 ttcagcatga aattgaccac attaacggta tcatgtttta cgatcgcatc aatgaaaaag
     9601 acccatttgc agttaaagat ggtttactga ttcttgaata aagaaaatcc cgttgcaaga
     9661 cggggttttg tgttataata gaggcatgaa aacaaatgat attgtctatg gtgtccacgc
     9721 tgttaccgaa gccctccttg caaatacagg aaacaaactc tacctccaag aagatctccg
     9781 aggtaagaat gttgagaaag tcaaggaact agctacagaa aagaaggtgt ccatttcttg
     9841 gacatcaaaa aaatctctct ctgagattac tgaaggtgct gttcatcaag gttttgttct
     9901 acgagtgtct gaatttgcct atagcgagct agattacatc cttgcaaaaa cacgccaaga
     9961 agaaaatcca cttctattga ttctagatgg tctaaccgat ccccataatc tgggttctat
    10021 cttgcgaaca gccgatgcga ccaatgtttc aggtgtcatc attcccaagc accgtactgt
    10081 cggagtaact cctgtcgttg ccaaaacagc cacaggtgct attgaacacg ttccaattgc
    10141 ccgagtgacc aacctcagtc aaaccttaga taaacttaag gatgaaggtt tctggacctt
    10201 tggaacggat atgaacggta ctccttgcca caagtggaat acaaaaggga aaatcgccct
    10261 catcattgga aatgaaggaa aaggtatctc tagcaacatc aaaaaacagg tcgatgaaat
    10321 gattaccatt ccgatgaatg gacatgttca aagccttaat gccagtgttg ctgcggccat
    10381 tctcatgtac gaagttttcc gaaatagact ataaaaaagt ttccagtcat ctgattggaa
    10441 acttttttat gattaactat gttctgtaat gaatttatag gcttcttgac cagcgatagc
    10501 tccatctcca accgctgttg ttacttggcg aaggtctttc aagcgaacat ctccaactgc
    10561 aaagataccg tcgactgcag ttttcatgtg gttatctgtc acaatccatc ctgcctgatc
    10621 ttggatattc aattctttaa caaaatcgct aagagggtcc aaaccaacat agataaagac
    10681 accaccgaag gcttgttctg tcacttgacc tgttttcaca ttttcaaata cgactgattc
    10741 tactcggttt tcacccttga tttcccttac tacagaatcc cagataaagc tgattttttc
    10801 attcgcaaag gcgcgatctt gtaaaacctt ttgggcacga agttggtcac gacggtgaac
    10861 aatggtaaca gtcttagcaa aacgagtcaa gaagagggct tcttcaacag ctgaatctcc
    10921 accaccaact accaataaat cttggtcacg gaagaaagca ccatcacaca cagcacagta
    10981 agaaacacca cgactgttca gttcttcttc tccaggcact cccaaaggac ggtgtttaga
    11041 accagttgct acgataactg tacgtgtttc atatgtttgg tcatcagtca tcactttctt
    11101 aaaatcacca tggtcttcga cattttcaac ataaccataa atgtgctcaa caccaagatt
    11161 ttcaagtggt tcaaacatct tttcagccaa ttcaggtcca ctaatattag cgtatcctgg
    11221 gtaattttcg atatcagatg tattattcat ctgaccacct ggcagaccac cttcaatcaa
    11281 agctactttt agattgcttc gagcagcata caaggccgca gtcatccctg caggtccagc
    11341 accgataata atagtatcgt acatatagat tccttctttc ttgttgtaac tatctttatt
    11401 ctaactcttt cttgtcaatc acgcaaggat tatgccttga aaacaagaat taaactcata
    11461 accgcaaagg ataatactgg gacaaccaag actccaatca taatcatatc atagagatgg
    11521 gcttggcgag ccctggctgt cttatcaact cccgacatgg ctctcagacc aatccaaatc
    11581 cctaaaaaaa tcagaacaag gatggtggtc aagatcaaac tctcgaaata taaagaaaat
    11641 agttgcagta gcatgatttc tctcatttct atctttttta aagagtaaac tcagctagtc
    11701 caactaactg agttttcctt tatctattat atcaaatata agtccgtttg taactagcga
    11761 agaattcttt tgtccgctct tctttagggg tgtggataat ctcatccgga gttccagact
    11821 cgatgatttt ccccttatct aagaagagaa ttttatccgc aacttgggct acaaaggaca
    11881 tgtcatgact gaccaaaatc atggtctgac ctgacttagc agcatctgca atagactttt
    11941 ctacttcacc gaccaattct gggtcaaggg ctgaagttgg ttcgtctaag agcaaaacat
    12001 ctggtttcat agcaagcgca cgcgctaggg caacccgttg cttctgtcca cctgataaat
    12061 ggcgaggata atggttttca cggtccgaaa gcccaacctt agccaactct tccttggcaa
    12121 tcttagtcgc ttcttggtca gataatttct tgacaacaac caagccttct ttcacattat
    12181 caagtgctgt tcggcgttca aataaattaa actgttggaa aaccatagac aacttacggc
    12241 gtagggcaag gatttcttct tgagtgattt tagaaaaatc aactgaaaaa ccatcaatct
    12301 gaatagagcc actgtcaggt gtttcaagat aattgagact gcgaagaaag gttgattttc
    12361 cagctcctga agaaccaatc aaggctacga cttctccttt ttgaatatcc aagttcagat
    12421 gatccaagac agtctgtcct gaaaaggatt tgcttaaatt cgaaatctta atcattaacg
    12481 aaggtctcct ttcacatctg tttgcactgt atcaggtgca gaaatagcca tttttctctc
    12541 gatgaaacga ccgaggcttt caattccgat attgactacc caataaacaa gggcaacgga
    12601 gatgaagcgt tcaaaatagc gataatcagc tccacctaga atctgagctt gggcaaagac
    12661 ttccacaaca cccgcactaa aagctagaga tgttcccttg gtcaaaccga tgagggaatt
    12721 aatcaaggtt ggagtagcta ccaccgctgc attaggaata atcactcgtc gataaacttg
    12781 cgctcgggtc atacccagac tgcgtgccgc ctcaatctca ccaggattaa ctgagagaat
    12841 ggctgcacga atggtttcac tagcataagc tgcctcatta aaggcaaaag cgacaatcgc
    12901 aaaagctgca gctggaatcg cattgatatt gagaccagtt ccccattgct gattgagggc
    12961 tttcaaagcc aaagggattc cgtagtaggt caacatgagt tgcaccaaaa tcggtgtccc
    13021 ttttaagaaa ctaacaaaga aggcctgcaa gggatataaa atcttgacac gattgatctt
    13081 cacaatggca aaaagaagcg ccaaaaccaa gccaaaaagg gcaccaccaa ttgtcaacat
    13141 aattgttgtt ggaagttgtt ggacaattct agggattcca tcaaagaccg aacgtaggct
    13201 aaacagcttg ccatccggaa tcaattgcat caagttttgg taccaatctg atgctaaaat
    13261 cgttgtaaca ttcataaaaa catcctcttc tgataatgat tcattctacc atgcttctgc
    13321 cgtcaatgaa attatttgct acggtcagat acagactttg tctacctact agtttatcat
    13381 actttgaaac agggaagtta tatattttat ctatcaaaga gatagataaa aactatttca
    13441 gtcccagttc ttcataagat tttcgataac cgatttgctt aacagttcca ttttctacta
    13501 aaatgggccg ttttaacaac ataccgtcac ttgctagcaa ctcagccgct tcttggtttg
    13561 acaaacttcc taccttatct tttagcccta attcacggta tttgatacca ctggtgttga
    13621 aaaattgctt caattcaaat cctgaggttt ctagccaatt caaaatgact tcttggctag
    13681 gtgtttcttc cacgatatgg acggctttat agtccacacc taattgattt aattcttgtt
    13741 ttgctttttt acaagttgaa catttggggt attcgataaa ttctaacatg tgcttctcct
    13801 tctatttgtt tatatcttta aaatctacgc cttcatgctc caagagccaa gctttctttt
    13861 ccactcctgc agcatagcct gtcagacgct tgcctgctcc caacacacga tgacaaggta
    13921 ctaggataga ccaaggattg cgtcccactg ctccaccaat tgcttgagca gaagccactt
    13981 gcaggtcttg agcaatttgt ccataggtca ctgtctgacc ataaggaatg ccctgtaaat
    14041 agtcccaaac tctcttttca aaattcgttc cgattggcgc caagagcaag ttggataaat
    14101 cctgaggctt gcctttaaag taatcatcta agcaagcaat aactgggtct aaaataggat
    14161 gactaacaac ttcttctatc gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct
    14221 gaacccaaat tccatacaaa taatggtcat cagctacaag tgatagaata ccaattggtg
    14281 aggagtagag tatttttaca tacttctttt gcattatttc tttaattttt gataggccaa
    14341 gcgttcgcca tctactggca ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg
    14401 ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa tcaagataat caaaaccttc
    14461 aatcaagccc tctaagaagg tttgagcaac tccttttccc tgcacatctg ctgccacagc
    14521 aatacggtga aagactagat actctgactc tccagcttgc cagtttccct cataaatagc
    14581 ttcataggcc tcctctggac tcttggtcac agcagcatag gctagcagtt ctccctcttc
    14641 caaggctacg taggcttgcc ctgagatgat atcatcgata ataacatctg catttggata
    14701 gccattttgc cactggtcac taccagcatc tgctaaacat tttttggcat cctccatcac
    14761 ctgcatgatg gcatctactt catttggaaa agctaaacga atttccatct tttttcctca
    14821 tttctgacta gtttctccca tcatagcata atttaagtat ttctacaagc agttaaaact
    14881 tgactttgtg tttttgttat tttataatct agttatcaaa actatataaa aaggagttaa
    14941 aaatgaaaac taccttttcc tacccaaaat gggcagaaat tccaaacatt gacctctatc
    15001 tggaccaggt tttgctctat gtcaatcagg tctgcgcccc tatctctcct aataaagaca
    15061 agggcctaac agcatctatg gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg
    15121 acaaaaaaaa ataccaacgc caacagattg cccgtttgat tgctatcaca accctcaagt
    15181 ctgtattttc tattcaagaa atagcccaga cacttaatac tctacaaact caagcaagtt
    15241 cagaccaact ctacgatgct tttgtggact acatgaacca aggaattgac ccagctaacc
    15301 ctattatcca aaccagctgc caaaccgtta aactctatca tcaaactcta gacttaatcg
    15361 atcatactca agaggaggta atccaatgaa cactagtctt aaactcagca aacaactcag
    15421 ttttggagag gagattgcta atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat
    15481 cttgctgcct atttcatcca tctatagtta tgaagcacac ggatttttat cctctatcgg
    15541 cgtttccatt ttcgtcatca gtctctttct catgttccta tcatccacca tttatcactc
    15601 tatggcctat ggttcgaccc acaaatatgt tttgcgaatc attgaccatt ctatgattta
    15661 cgttgccatt gccggatcat acacgcccgt tgtcttgacc ttgatgaata actggtttgg
    15721 ctatctgatt attgtcatcc aatggggaac gaccatcttt ggtattctct ataaaatctt
    15781 tgctaaaaag gtcaatgaga aatttagcct tgctctttac ctgattatgg gctggttggt
    15841 tctggctatc attcctgcca ttatcagtca aacgacaccc gttttctgga gtctcatggt
    15901 aactggcgga ctctgttata cagttggagc tggattttat gccaagaaaa aaccttattt
    15961 ccacatgatt tggcatctct ttatcctagc tgcgtccgca cttcaataca tcgctattgt
    16021 ttattacatg taaaaaagtt gagaaattca atctcaactt ttttctttac acatattgat
    16081 aaagtactgg tgcaagcgca catcatcagt caattctgga tgaaaagaac ttaccaacat
    16141 atttttttct tgggctgcaa caatttgatt gttcactgtt gctaaaattt ctacaccctc
    16201 accaacacta ctgataatcg gaccacggat aaaggtcatt ggaatcttgc caactccctt
    16261 acattctgct tccgtgtaga aacttcctaa ttggcgccca taagcattac gctcgaccac
    16321 catatccata gttcctagat gactctcttt ctgagaagtg atttccttag ccagcaaaat
    16381 taagcccgca caggtcccaa acactggtaa gccagataga atggcttctc ggatgggaag
    16441 tagcatgttc tggtcacgta agagcttgcc catggttgta gactcaccac caggcaaaat
    16501 caaacccgac aagtcactct gatcttgctg aaaatcatct agatttctga gttctacact
    16561 ctcgacacct aattgatcta gcacttttgc atgttctgca aaggcccctt gcaaggccaa
    16621 tattccgatt ttcatctatt ttcctcgttc agccatgaga atttggattt cattttcatt
    16681 aataccaacc atggcttctc ctaaatcttc agagatttga gctaggattt gaggattacg
    16741 gaagttagtc acagccttaa caatggcact cgctcgttta acaggatctc ctgacttgaa
    16801 aatacctgaa ccgacaaaga ccccctctgc ccctaattgc atcattaacg cagcatctgc
    16861 tggcgttgca acacctccag cagcgaaatt tacaactggc aattttccat gttcatgaac
    16921 atattggacc aattctacag ggacttgcaa atccttggca gcaacataaa gctcgtcctc
    16981 acgtaagttt tgaatgcggc gaatttcctg attcatcata cgcatatgac gaacagcttg
    17041 gacgatatcc cctgtccctg gttctccttt ggtacgaatc atggaagcac cttcagcgat
    17101 acgacgcaag gcttcaccca aatccttagc accacagaca aaaggaactt ggaattcttt
    17161 cttgtccaca tggaaacggt catcagctgg agatagaact tcactctcgt cgatataatc
    17221 aatttcaata gcctctaaaa tctgagcttc aacaaaatgc ccgattctga ccttagccat
    17281 tactggaata ctaaccgctt cttggatttc cttaatcatc tttgggtcgc tcatgcggga
    17341 aactcctcca gctgcacgaa tatcagccgg aattcgttcc aaggccatca cagctgccgc
    17401 accagcagct tctgcgatac gagcctgttc aggattctgc acatccataa taacaccacc
    17461 cttgagcatc tgtgccaagt ttttatttag ttcataacga ttttcagtca tttgttttat
    17521 cctcatcatt tgtattggta gctacctttt cattttaagt cagaacagaa tgaagcacaa
    17581 gataaaaaaa ctataattgt atggggacaa attagctaaa aactatctga ccttaactta
    17641 aggccagata gctcattcat ttttattttt cagccgtaag ggcagccatt gtgatgtagt
    17701 tgtatggttt gttgaagtgt ggcaagaaga agaggtctgt caatgccaat ttatcaattg
    17761 tcacatgctc ttggatagca agtgagaaca tgtggattcc catgctaatt gcaatatcat
    17821 gtgaaaccat ttgggcacca agaatttcac ggctatcttt gtcaaagaca atcttaattg
    17881 ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg aagatcgtta aagcctgttt
    17941 cagttgcgtt gtaaccagca gctttcgctt tttcaagagt caaaccagtt gaaaccatgt
    18001 gaagaccgta gattgagata ccatttgaac cttgaacacc gattccttcc aattcatgtc
    18061 cacaagcatt gtaggcacca acgataccag tgcgaacagc atttgaagca agagcgatat
    18121 agcttgtatc tttacgagca ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgt
    18181 ctgggataga tgtttcttgt ttcttgtcta caaggaaggc accgttgcgg aagagttcga
    18241 tcttaccacc tgcaagggct gtgtttggac ggaaaccaac tgcaaggata accatatcca
    18301 cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt accgtcacct tcgattgctt
    18361 taacagtttg acctagagcc aagcggatgt tgtgatcttc caagttcttc gccatcattt
    18421 gtgtgaagtc tttgtcatag taaccgttca agacagtatc aacgatatca acaaggacaa
    18481 cttcttttcc aagacgttca aaggcttcag caagttcaac accgatgtaa ccaccaccaa
    18541 caacggcgat acggtcgagg tgttggctct tgtcagaaag tttattgata acttcttcag
    18601 cattttggta caatttcacg aattgtacgt tttcaagagt tgctttaaat tcgcggtttc
    18661 ctttaacaat ttcaacacct tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa
    18721 tcaatttttc gtatgattct ttgtgctctt ttccttcaac ttccgctgta actactttgt
    18781 tatcatagtc gattgaaaga acaggtgagt tcatgtaaac tttagcacct ttagcttcca
    18841 atttttcttt atcagaatag aacaagcctt cagcaccgtc aatttgttca ccaatccaaa
    18901 gagccattcc acatcctagg aaagagatgt tagagttttg gtcaaataca acaatttcgt
    18961 tctcatttcc aaaattatcc aacatggtat tgatacatgc tgtaccagcg tggttagcac
    19021 cgactacaac gattttactc ataaaaattt cctgccttca ttctaaattt accttactag
    19081 tataccattt accgttagcg tttacaaggg gggtactatt atttcagcat tttttatcaa
    19141 aaataattcc ccatttatcc tgttttcaag cctgatgaat tttatgagca tatttcttga
    19201 ctttttccaa attttgtttg tgaaaattct aactttatgg tattataata acatgaaaat
    19261 gaaatgtaag ggcttcaatt tagatgatta tttgatatta caacttattt tctataagag
    19321 aaaggagttg gtagcttgac tcttcgttca cattctgaac ggctaatggg gactactatc
    19381 actatttcat tagtggatga gcaagccgat atctttctcc aaaaatcctt tgacttgctc
    19441 aaagaacttg aataccgctt caacgccaat agtcaagaat ctgagttgat ggaaatcaat
    19501 tatcaagcag gaatagcccc cgtcacggtt catccagacc tgtttgagct gatttcactt
    19561 gggttagagc atagcctagc gctctctagc cacctcaata tcagcattgg tcccttaatt
    19621 caaacctggc gtatcggttt ttcagatgcc aaggtcgccc agcctcaaga aattgaatcg
    19681 gtgctgcctc taatcaatcc tcatggtatc gagttagatt cttctacttc tactgtgttt
    19741 ttaaaacaga aaggaatgaa gatcgatcta ggttgtttag ccaaaggata cagtgcggat
    19801 aaggttgccc aatttcttag gaaagagggg gtgacttctg ccttgatcaa tctgggaggg
    19861 aatatcctga ccattggaaa aaatcaggca agaggggata acccatggca aatcgggatt
    19921 caagacccag ccaatcctag gggaaatcat ttaatgacca tccctgttgt caataaatct
    19981 gtcgtgactt caggcattta tgaacgtcac ctgaccgtcg atggacaaga ttaccatcac
    20041 atttttgaca gtcaaacagg atatcctgtt gaaacggaac tagcgagtct aacaatcatc
    20101 tctgataaat cagtcgatgg cgaaatctgg acgactcgac tctttggaga aagacctgct
    20161 tctatcctct ggcaagtcga aagtttggag ggcatcgaag tcatcctcat cgataaagaa
    20221 ggccacctaa gctgttcttc aggaattcct actctataga gacaactgtt tcaatggaat
    20281 tttaaaattg tattatgtaa aaagagaaag gaaatctcat gttaaaactt attgctattg
    20341 ttggaacaaa ttcaaaacgt tctacaaacc gtcaattgct tcaatacatg caaaaacact
    20401 ttactgacaa agctgaaatt gaacttgttg aaatcaaggc cattcctgtc ttcaacaaac
    20461 cagctgacaa gcaagtacct gctgaaatat tggaaattgc tgctaaaatc gaagaggcag
    20521 atggcgttat tatcggtact cctgagtatg atcactctat tccagctgtt ttgatgagcg
    20581 ctcttgcttg gttgtcttat ggtatttacc cacttttgaa caaaccaatc atgattacag
    20641 gtgcttctta cggtacgctt ggttcatctc gtgcccaatt gcaacttcgt caaatcttga
    20701 atgctcctga aatcaaggca aatgttcttc cagatgaatt cttgctctca cactctcttc
    20761 aagcatttaa cccaagtggc gacttggttg accttgatgt tatcaagaaa ttggatgcca
    20821 tctttgatga cttccgtatc tttgtaaaaa tcacagaaaa attacgtaat gcacaagaat
    20881 tacttcgcaa agatgctgaa gactttgact gggaaaattt gtaagatagg agaccaaaaa
    20941 gaatgaaatt tgttggactt gttggatcaa actacgatca atcatataac cgtaagctct
    21001 tggaatttat ccgtcgctac ttcaaactca aatttgaatt agaagttctt gaaattgacg
    21061 aagttccaat gtttaaccaa gatgaaaaat gggatgaaag tttccaatta cgttatttat
    21121 ataacaaaat tactcgtgca gatggtgtta tcattgctac tcctgagcat aaccacacta
    21181 tctcagcttc actcaaatct gtacttgaat ggctttcata cgaagttcat ccatttgaaa
    21241 acaagcctgt tatgattgtg ggtgcatcat actatgacca aggaacatca cgtgctcaag
    21301 ttcaccttcg taaaatcctt gatgctccag gtgttaatgc ctacacgctt ccaggtaacg
    21361 aattccttct tggtaaagct aaggaagctt ttgataacaa cggaaatatc accaacgaag
    21421 gcactgttaa attccttgaa acttgcttag ataactttgt taaatacgta ggagtcgttt
    21481 cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt ggattgtgga aaaccaatcg
    21541 ctacaaccat cacagaagtt gaccctgacg atccagaatg ggtagaaaaa gttgcagcat
    21601 tcactggtgc tgtttctggt gatacctatg tcaaattgga ccacggtatc ctaacagtta
    21661 accaaattga tatgttcttg aaagctatgc catttgaatt gacatacgct gacgacaaca
    21721 accaattcct ctactacaac aacgctcacc aagatccaga cactatgttc gctaaacgtg
    21781 taccacctca atcaggtagc cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta
    21841 tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta
    21901 cgatcgttcc aggttctcct gcaggtgtta tcaacactca caactaccaa gcaatgtact
    21961 atcctgatgg atcatacgct ggtatcaatg aaatcgtctt taacttccaa ccatggcttg
    22021 actggtacct aaaagagact ggtcaacgtt tggtgggtgg tagcggacca tttgctcctg
    22081 ctgccggagg tcatggagac gccgatgcta cttctagcgc ttctgattca ggggatgctg
    22141 gaggccacgg tggtgacgca gacgctacag ccggtgcaag ttactaatga tagtttttag
    22201 gaactattat ggttcctttt ttagcgaaaa aagactagca aacacaaact gctagtctct
    22261 ttgttatcgt ttcatctatc tttgttaaaa gaaagaatac atatactcaa tgaaaatcaa
    22321 agagcaaact aggaagctag ccgcaggctg tacttaagta cggcaaggtg aagctgacgt
    22381 ggtttgaatt tgattttcga agagtattat tatgaatttg gatcatcaag actacggcca
    22441 tgtaatcctt tttcacgttg tacttggcgt agtttttctg gtgtaacatc gtttccttct
    22501 tcgtccacaa ttttgattcc ttcaatgtgg tgacgaacag cgcggcgata accttcgatg
    22561 tactcctcac gtagtttggc ttgttccact ttttcttctg gtgttaagcc ttctgttttt
    22621 ttctttttag caagctcatt gatacgagca atttttttcg gatccatttc ttctcctttg
    22681 taataagata aagtccgttt atcaaatttt atttagtgtt aatttggtta aaacaagcaa
    22741 acttagctgc tttcttggtt agttgtgaca agattgccaa acgattttga cggacagcct
    22801 gatcttcagc cattaccata gtattttcaa agaaagcatc aatgactggg ctaagcgcaa
    22861 aaagttgttt caattgctga cttgcaggtc ctgataaaat gagtgtttct actgcttctg
    22921 ccaaagcttt ttcttggtca ttctcaaata gtgctgaatc aaccgtagca accccttctg
    22981 ccttctcggc caggttaaag gcacgagaaa gtgattcaac agatggttta aaatcttctt
    23041 ccttgcttac ttctacgaga gcacttgctg cttccaacat atctgccaca acaaagtttg
    23101 aacctgcaag aactgcttcc ttgatatctt ttggagtaga gcccatcatc ttatcaacac
    23161 gagccttgat aaagtccata acctctgctt tattttcata agtcaaactg tcaaatttca
    23221 atgcataaag gctatcaatc agctcatcca tagcaatgtg ccaaccaaag gcatccaaga
    23281 tacgaaccac accttgagtt gcacgacgaa gggcataagg gtcattagaa cctgatggaa
    23341 tcaatcctac tgagaagaaa ctcaaaatcg tatccaattt gtctgcaatg gctagaactg
    23401 cgccgacctt gctctctgga agttctcctt cagctgatgt aggcatgtag tgttcacgaa
    23461 tagcagctgc caccgctgga gtttcaccag caagaagggt gtatttttca cccataattc
    23521 cttggagttc gtcaaattca ccaaccatac ctgtcaacaa gtcaaacttg taaatggctg
    23581 ctgcacgagc aaggtcaact gtttcatcca ctgacaaact agctttttct gccaaaagta
    23641 cagtgatttg acccgtacga atcatgtgtt cacgaaggga accaatcttc tcatggaagg
    23701 tgacattgtt taatttttca acaagatctg aaatcaccaa tttttggtct tcacgccaga
    23761 agaattctcc gtcttccaag cgggctacca agactttttc atttcctttg atgacatttt
    23821 tcaaacgctc tgcgtttccg ttacgaacag aaatgaagtt tggcaagagt tttccatctt
    23881 gatcacgaac aacaaagtaa cgctggtgtt ccttcataga agtcaccaag acttcttctg
    23941 gaacttcaag gtatttagca tcaaaacttc ccatgaaggc agttgggtat tcaaccaaat
    24001 tcaagacttc attcagcaaa tccgcatcaa tttcgatacg tacaccatgt tttgcctcaa
    24061 tttccttgat ttggtcaaca atcatttgct cacgttcaca tggatctgcg attacaaact
    24121 gcttacgaag gtcttcttca tagctcaatg ctgactgaat cttggtttct tgtcccaaaa
    24181 aacgatggcc acgactcaca cgacttccct tgatatcaag gaaatccaag tcaaactctt
    24241 gctcatccaa gagaacagtt aaagtgtgaa cagggcggat gtattcaaag ctatttcccg
    24301 cccagtgcat gctgacaggg aaagtcagtg acttcaagac atccacaatg cctggaacaa
    24361 tggcttcaac tgcttgacca atttcttcct tagtgacata gacatattct tcacccttga
    24421 tttcacggaa ttcgatatct tcaacagtca aacctttccc acggacaaat ccttgagctg
    24481 ctttggtgaa gtttccatca ctatctaagg caattttctt tgctggaccc ttgaaatctt
    24541 ctgttaaatc agactgtttg tctgcaagac cagttacacg aacagccaaa cgacgtggtg
    24601 ttgagaaagt ttgaatggct tcaaaagaca ggcgttttcc cttgaggaag gctgccattt
    24661 tttcgcctag ttgtttttca cttggcgtaa caacataggc tggtaattct tcaagaccga
    24721 gttctactaa taagtttttt gtcatgtttt ttcctttaca ttttcttcaa tcttttttga
    24781 tatgcacctt aggtactggg gacgtcgcta actaactctg tgagtctgta tggaaatcca
    24841 atgctaaatt tatcaagatt tccaacaatc tcatcaaagt ggatttagct gactgatttt
    24901 tgaacctaag gtttcaaaaa tccccacata acagtacagc ggtgcatatc cctctagcaa
    24961 gtcttcgact tgcctctaac gattttagag tacagtatta ctcactattc tgcgtcttct
    25021 gctaaaagtt taactcgtgt ttcttcatcc aaaagtgggt aacctaggcg tttgcgttct
    25081 gcaacaaagg ttttggctac aacacgggcc aagttacgga tacgagcgat atagcctgca
    25141 cgctctgtta cagatacggc accacgcgcg tcaagcagat taaaggtatg tgaacatttg
    25201 agaacatagt cataggcagg gtgtaccaag ccttcttcta atgcacgacc agcttctttt
    25261 tcaaacttat caaaattttc aagcaacatt tcttggtccg aaatttcaaa tgaatatttt
    25321 gagtgctcat actcaggctg gataaagatt tctccgtatt ttacaccatc agcccactcg
    25381 atatcataga cagagtctac ttcttgaatg taagaagcca agcgctccaa accataggta
    25441 acttccgcag tcacagggct agttgccaat ccaccgactt gttggaaata agtgaactga
    25501 gtgatttcca ttccgtcaag ccaaacttcc caaccaagac cagctgaacc agttgatggg
    25561 ttttcccagt tgtcctcaac aaaacgaata tcgtgctcca aaggattgat tcccaatttt
    25621 tccaaagact caaggtaaag ttcttggata tttgatggag aaggcttcat gaccacctgg
    25681 aattggtggt gttggtagag acggttaggg ttttccccat aacgaccgtc agcaggacga
    25741 cgtgatggct ctacataagc tgcattccat ggctcaggtc cgatagcacg aaggaaagtg
    25801 taaggactca ttgttcccgc acctttttca ttatcataag cctgcataag catacaacct
    25861 tggtcattcc aaaattgttg caaagtaagg atgatttcct ggaaagtcaa tttcttagac
    25921 attgtttact cctttagttt ttatatttct ttttcaatta atttctgctg aacaaaccaa
    25981 tctaacaagg gaaaagtttt ttctgtattt gcccataaat gataagaatc taagaccgct
    26041 tgtacactac ctaaattttc taccaactta tctactgtca aaaagctgcg ccagtattca
    26101 taaaaaatac ttgcatagtt cttatcataa gtcgaagaac caaaatcatt caatgaatgc
    26161 caaccatact tcttctgaaa aagttctacg agagattgat tacaaatttt ttccgcttga
    26221 aattcctctt ctgtcaagaa atacttgcga ctaatatatt caaccatccc ctcttcgaac
    26281 cagatataag agtcataacc atcaaaatca tctaaaaaat gctccgacca atgagctaac
    26341 tcatgtccta caatctgtaa gaggaaattt tcagataaag aatgatagtg actttctatt
    26401 gcttgagttt gctcagaaca ctcgtagtcc atcaattgat acaaatacaa ctctttccaa
    26461 acagctaaat caggcgccat aaccattcgt ctattatttg tataggctgg aacagcgctt
    26521 tccctaataa tctgtgtagc agcattaaaa tctgaccaaa taacggcttg cggtaaatca
    26581 cagactgcaa gttcattctt taaaaaagat tgataatctt tcaacttttc agtatttctt
    26641 actacaaaat cacgaaatgt agctagttga ctatcgtctt ttacaagata aaggttgtcc
    26701 acggctctcc tttctttcac acaatagact gaataagcaa aagaaccaca tctgacaatc
    26761 ctaggttgat ttaacctagg ggcgtcagaa acgcggttcc accctaattt attacttcat
    26821 tgtttttgaa aatactacag aaagcgccag ctcattattt tgccctactt ggctcccact
    26881 gtcccaagct cgcttgaaga acgccataag actttctttc ctgctgacta ttatatcaaa
    26941 aattagaata atgtacaatt ctttttatga ttttctagaa atccacatca tcaactcgtg
    27001 gagcccccga ctgaacagca gtcgttttta aggtttctct ctcctcatga ctcagttcaa
    27061 ttccaaaaca atcaagatta gcttgaatac gagaggttgt gacagatttt ggaagtggta
    27121 aaaatccttc tgccaagctc caggccaagg ctatctgagc aaccgatttt ccgtgatttg
    27181 ctgcgatttc ttggacttgc ttgctatcaa acagttctcc ttgtccaaaa ggcccccaag
    27241 cttccaataa aattcccttt tcacgacagt aagctacgac ttcctcttga tacacacctg
    27301 gcgccaagcg aacttgattg accgcaggaa cgatagttgc agtttcaagc aaggcatcca
    27361 aatgatgggg aagaaaattg ctaacgccga tagcacggat tttcccttct tgatagaggt
    27421 cttccatcgc tctccaaact tccgcattgc gagttttcca tgcgtcattt tctctgagcg
    27481 gttttgggtt cggccaatga atcaaataca aatccaaata atccaagccc agtttttcta
    27541 tagatttttc caaagcttga cgagtttgct cataggtttg ctgactattc caaagcttgg
    27601 tagttacgaa catttcttca cgtggaactc cgctatcttt gattgcttga ccaacacttt
    27661 cttcattctg ataaatcgcc gccgtatcaa tatgacgata accagccttc aaggattcta
    27721 acactgcacg ataggcttct tctccatcct tagccttaaa agttccaaat cccaatactg
    27781 gaatttctac tccattattt aattgatagg tattcatatg cttctccttc tatatttatt
    27841 catcaattat agcataaaac attttttaag tagtactatc ttctgtaaaa aataagtctg
    27901 tcaaatatct aacagaccta ttttttcttg cttattcatc acgactatag tacagctcat
    27961 gagcttttag gcgagtattg agcatctctg gtatggtcac aaaggtataa ccttgatttt
    28021 tcaaatactc aatgaccctt ggcaaggcat tgactgtcgg actgtgaata tcatgcatca
    28081 aaacgataga gccgttagct acttgatgct gaatttctgt caaaatagat gcttcatttt
    28141 tactcttcca gtccagacta tccacatccc acatgataaa gctcaaatcc aagctattgc
    28201 gaatatcatc tgtaatagca ccataaggtg gacgcatgag tttagaacta gaacccagca
    28261 ctttagttag cacatcctca gtatcagtaa tctgcttttt agcttcatca agagagagtt
    28321 gcgagagaat cggatggctc caactatggt ttccaacaac atgaccttca gattttatcc
    28381 tcttcaccaa gtcctcattc ccagaaacat ttttcccaag cacaaagaaa gtcgctttaa
    28441 tatcatattt agctagggtc tctaatacct gcggggtcgt tgctggattt ggaccatcat
    28501 caaaggttag agcgacaact ttttgatatt tcttatcaaa gtaagattgg tacaaggccg
    28561 catctttttc gagtaagtac gaagattgga taacatcaaa gaaagcagat actggcaagg
    28621 ctatctcttc taaattttca accacaggac ttggataaag gataatctga ctatccttgt
    28681 aatcaaaatt ccatgcagac aagtcttggt cagagaagtt ttttacaatc tgctcactct
    28741 ggtcttgctc tattttttta tcctctatga aggaggtcaa ctcttttatc agctgttcct
    28801 tagccttact agcatctgaa aacagttggt caagtgtaaa aggttgccca tcttctgtta
    28861 agtgaacctt tcctagactg gtcttttcag tctcttcaac cttaaaagca actaaatcat
    28921 agatttgttt ggtcacatta cgattaacga ctccctttaa acctgactct tcttgctctg
    28981 tatagtagaa aacaagattg tccttacttt ctagcttgtc cttaacatct tgatttatca
    29041 actccctaac agaggaaatc actttctccc cttggagagg ataataggca atcacttcgg
    29101 cttgcccctg acgaaaatgc tccttctgat ttccctcact caattgatca tctttctctt
    29161 ttttgagcga ttcaatcttt tgctcaaaac ttttttgctg gtagatctta aaagcaataa
    29221 atccgcctaa taggcaaata gaaattgcta aaataccaat caaagccaat aatacatgtc
    29281 tcgttttccc gtgtctgcca cgtcctagtc tacttttatt catatttata tcataacaaa
    29341 tttgagcaat aatttcaatg atacaatttg gcaatccaca attcctctag caagccaaag
    29401 catcttacat caactccaac atccgtatct gtagagatta tgtagttttc tatctatgga
    29461 atttctagta gattgaagct agaatagtag acctatactt ctaaaacatt gttagaaatc
    29521 gatttgattg tcctgatcga tttgtcctgt tctcatttca ttttactata aaactatgaa
    29581 aagctaggtc atctgagaag taattactat cgacaattgc gatagcgtat actggtgcga
    29641 tttgtttgta gctctggtgg gtatcacctt cacgttggcg aattttttct aggttttgat
    29701 taacctgact gcacagataa gcccataggc gattgatgaa aaaattctga tgatgaacct
    29761 gaatttcgat gataacttgg attccattat ctaactccgc caagacgtct atactagtat
    29821 agaaatcctg cgctgagtag ggcatggaag gcaagacgtg aatgttactt ccctccaaaa
    29881 tcgtcacatt ttttgctggc aagtccagca tatcgcggat aaattgacaa atcattagtt
    29941 gggctgatac ccggatgtct gagaatcctc cttttcctcc ttctattata gcacattttt
    30001 aaatctaggt ttgctagatt ctatgcttct atctatttat tcggaaaaga aagctaatag
    30061 cttatttgaa attttctcct ctctgttgga tagtcccgtc tatctatgtt ataatgaaag
    30121 aaggatttaa aatcggaaaa ggagtattta tgctaaaatt aggtgtcatc ggaactggcg
    30181 ctatcagcca tcatttcata gaagcagccc ataccagtgg agaataccaa ctggtcgcaa
    30241 tctattctag aaaactagaa actgcagcaa cctttgcttc tcgctatcag aatatccaac
    30301 tattcgatca attagaagtc ttcttcaaat cttcttttga tttagtctat atcgccagtc
    30361 caaactcctt acattttgct caggcaaaag ctgccttgtc tgctggtaaa catgttattc
    30421 tcgaaaagcc agctgtcact caaccacaag aatggtttga tttgattcaa acagctgaaa
    30481 aaaataactg ttttatcttt gaagcagctc gtaattacca cgagaaagcc tttactacta
    30541 tcaaaaactt tttagcagat aagcaagtgt taggagcaga tttcaactat gccaaatact
    30601 cttccaagat gcctgacttg ttgactggac aaacaccaaa tgtcttttca aaccgttttg
    30661 ctggtggagc cctcatggat ttggggattt atcccctcta tgctgctgtt cgtctttttg
    30721 gaaaagccaa tgacgcgact taccatgctc aacagcttga caatagcatt gacctaaatg
    30781 gagatggtat cctcttctac ccagactatc aagttcacat caaggctgga aaaaacatca
    30841 cttccaatct tccttgcgag atttatacaa cagatggaac cttgactctc aacacgattg
    30901 agcatattcg ctcagctatt tttaccgacc accaaggaaa tcaagtccag cttcctatcc
    30961 aacaggctcc tcatacgatg actgaggaag tcgctgcatt tgcacacatg atccagcaac
    31021 cagatctgaa tctctaccaa acttggctgt atgatgcagg ctctgttcat gagctactat
    31081 ataccatgcg ccagactgct ggcattagat ttgaggcaga aaaatgaaaa ccaaactacc
    31141 gactgaatgg caagaactga gtgaccaact cggtttccaa gaattcaccc ccattcaaac
    31201 tcaactattt gagccccttc ttgctggaga aaacctccta ggagtgagcc aaaccggaac
    31261 tggtaagacc ctagcgtatc tcctaccaag tcttctcaga ctacaaaaga aaaaagccca
    31321 acaactcttg attctagcac caaacacgga acttgctgga cagatttttg atgtatgtaa
    31381 aacgtgggca gaagctatcg gattgactgc tcaactcttc ctttcaggtt caagtcagaa
    31441 acgacaaatt gaacgcctta aaaaggggcc agaaattctg attggaactc ctggccgtat
    31501 ctttgaactc attaaactta aaaaaatcaa gatgatgaat gtggaaacca tcatcctgga
    31561 tgaatttgac caattactag atgattctca gattcacttt gtagaaaaaa tcactcacta
    31621 cgcacctcgt gaccaccaac tggtctacat gagtgccacg accaagtttg accaagaaaa
    31681 gattgtgccg aatacacgca ctattaatct ctctgaccaa aaattggaca atatccagca
    31741 tttctacatg caggtagacc aacgtcatcg agtggatatg ctacgaaaac tggctcatgt
    31801 agaggatttc cgtggtctag tcttcttcaa tagcctgtca gaccttggga atgccgagga
    31861 aaaactacag tatcgtgata tattgactgt ttccctcgct agtgatgtta atgttaaatt
    31921 tagaaaaatc atcttagaaa agtttaaaga taaccaacta accctgcttc ttgcaactga
    31981 ccttttggct cgtggaattg atatcgatag cctagaatgt gtcgtaaact ttgatattcc
    32041 tagagatagc gaaacctaca cacaccgtgc tggccgtact ggccgtatgg gcaaggaagg
    32101 atatgttatt actctcgtca ctcatccaga agaaatcaaa aaacttaaaa agtttgcaag
    32161 tatccgagaa attgtcctaa aaaaccaaga actctatatc aaataaagcc ccattgctct
    32221 atacacatcc agtgtatgga gcttttttat aagcaattca attttatact catctgcttt
    32281 caaaaagcat tctattccat ctccgattaa cgatggactt tatcacctcc ttctccagtc
    32341 cttgtatgac atcttggagt tgattcatga catcttccaa agttcgaaag gctttattct
    32401 taaatccacg tttacgaatc tctttccaca cttgttcaat gggttcatct ctggtgtgta
    32461 tggaggaata aaggtaaaat caatattagt cggaatcttt aaggtacttg atttatgcca
    32521 tatagcattg tccataacga gtaaaaaata atcatctgga taagcttgtg aaagctcttc
    32581 taaaaagacg ttcatccact cagtattaca tccaccagct attaagaaaa atgattcgcc
    32641 tgtatggggc atcaacagct ccataacaat agcgaaattc tcgtatatag tgactatgga
    32701 catgtggacc tactcctatt ggagaccaac aagatcccag tttactgatt ctaccgaaac
    32761 cagcctcatc ttggtacatc aagcgaacct tatgaaaagg tctactggtt ttaaagcgct
    32821 ttcttgtctt cttgaattga gattttattt ttagacgcga caatggtttg agcgtctgct
    32881 ttcctaggat gttctggacg tggcataata tttcgccaac catggtgctt caacagttga
    32941 tagaaggcat cacgtgtgta ggaacgatat aagcctgaaa taaggtattg taacaaattc
    33001 tcctgcctct gtagccttca aatggcgggc aagaaaggct ttctcttcct caactgtcat
    33061 atatgcatgg ttacgaccac cacgtgtttc ttgaaggaga gagtcgagtc cgaactcctc
    33121 atattttttt acatttcgcc aaatcgttgt ttgattacag tctaaaagat ctataatctc
    33181 tttataagat ttgcccatca gacgaaatag aacgatttga aggcgtttat gatatttagc
    33241 tgtacgaaag tcttttaaaa gtgttttgat ggtttggatt tcttctttag ttgatttcat
    33301 attactattg tataatgctt tttgatttga gtctagtatt atactcttcg aaaatctctt
    33361 caaaccgcgt cagcttcgcc ttgtcgtata gaatgttact gacttcgtca gttctatcta
    33421 caacctaaaa acagtgtttt gagcagtctg cagctaactt tctataacaa aatgaaataa
    33481 gaacaagaca aatcaatcaa gacaatcaaa tcgatttcta acaatgtttt agaagtagat
    33541 gtgtactatt ccagtttcaa tatattatag tttgctcttt gattttcatt gagtattagt
    33601 tcaatatcta aaaaaagag
//
LOCUS       DAVKBK010000020        32887 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVKBK010000020 DAVKBK010000000
VERSION     DAVKBK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.020"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..395)
                     /locus_tag="VWX69_001020"
     CDS             complement(<1..395)
                     /locus_tag="VWX69_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192382.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWI"
     gene            complement(392..724)
                     /locus_tag="VWX69_001021"
     CDS             complement(392..724)
                     /locus_tag="VWX69_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU9192383.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(780..1682)
                     /locus_tag="VWX69_001022"
     CDS             complement(780..1682)
                     /locus_tag="VWX69_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192384.1"
                     /translation="MMRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(1688..2005)
                     /locus_tag="VWX69_001023"
     CDS             complement(1688..2005)
                     /locus_tag="VWX69_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192385.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGDWNTFKNNIKGLARASSGFRF
                     AARETGLWAAIWSTRVYSYTYVVSAFAPILGSVAAVNAALAVIGGISVAGITYALWTR
                     KFY"
     gene            complement(2150..3502)
                     /locus_tag="VWX69_001024"
     CDS             complement(2150..3502)
                     /locus_tag="VWX69_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEU9192386.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQALQNELLQLQQQGDSPSLSDTTSADNKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLLPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(3499..3966)
                     /locus_tag="VWX69_001025"
     CDS             complement(3499..3966)
                     /locus_tag="VWX69_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9192387.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(3959..6178)
                     /locus_tag="VWX69_001026"
     CDS             complement(3959..6178)
                     /locus_tag="VWX69_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU9192388.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIMEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            6644..7507
                     /locus_tag="VWX69_001027"
     CDS             6644..7507
                     /locus_tag="VWX69_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9192389.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            complement(7796..9187)
                     /gene="argH"
                     /locus_tag="VWX69_001028"
     CDS             complement(7796..9187)
                     /gene="argH"
                     /locus_tag="VWX69_001028"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU9192390.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAYHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TTGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(9216..10413)
                     /locus_tag="VWX69_001029"
                     /pseudo
     CDS             complement(9216..10413)
                     /locus_tag="VWX69_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(10430..11236)
                     /locus_tag="VWX69_001030"
     CDS             complement(10430..11236)
                     /locus_tag="VWX69_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9192391.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLVTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYSVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(11443..12084)
                     /locus_tag="VWX69_001031"
     CDS             complement(11443..12084)
                     /locus_tag="VWX69_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192392.1"
                     /translation="MIELENITKTIGGKVILDRLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            complement(12081..14189)
                     /locus_tag="VWX69_001032"
     CDS             complement(12081..14189)
                     /locus_tag="VWX69_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9192393.1"
                     /translation="MKKISHLCMLLLLLCTTFFVLNVNVTREIVRIQEMGKTTYSFDL
                     YLKDVTKPTETILQFFEEVASQDKVSIIKVDNGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLFSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSLPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     ALASRMEKRSLVELLKGGIL"
     gene            complement(14244..14537)
                     /locus_tag="VWX69_001033"
     CDS             complement(14244..14537)
                     /locus_tag="VWX69_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9192394.1"
                     /translation="MIGEINHEKISVASLMVCSILASTSVLAVWVDGGQWNYGVGWSG
                     NFGYSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            14943..15263
                     /locus_tag="VWX69_001034"
     CDS             14943..15263
                     /locus_tag="VWX69_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9192395.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(15315..15902)
                     /locus_tag="VWX69_001035"
     CDS             complement(15315..15902)
                     /locus_tag="VWX69_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9192396.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            16144..16815
                     /gene="sdaAB"
                     /locus_tag="VWX69_001036"
     CDS             16144..16815
                     /gene="sdaAB"
                     /locus_tag="VWX69_001036"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU9192397.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            16824..17696
                     /gene="sdaAA"
                     /locus_tag="VWX69_001037"
     CDS             16824..17696
                     /gene="sdaAA"
                     /locus_tag="VWX69_001037"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU9192398.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            17718..18350
                     /locus_tag="VWX69_001038"
     CDS             17718..18350
                     /locus_tag="VWX69_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9192399.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            18376..18474
                     /locus_tag="VWX69_001039"
                     /pseudo
     CDS             18376..18474
                     /locus_tag="VWX69_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(18656..20506)
                     /locus_tag="VWX69_001040"
     CDS             complement(18656..20506)
                     /locus_tag="VWX69_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9192400.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(20548..21705)
                     /locus_tag="VWX69_001041"
     CDS             complement(20548..21705)
                     /locus_tag="VWX69_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9192401.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENVEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            21763..22929
                     /locus_tag="VWX69_001042"
     CDS             21763..22929
                     /locus_tag="VWX69_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU9192402.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            23068..23394
                     /locus_tag="VWX69_001043"
     CDS             23068..23394
                     /locus_tag="VWX69_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9192403.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            23381..23974
                     /locus_tag="VWX69_001044"
     CDS             23381..23974
                     /locus_tag="VWX69_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU9192404.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            23967..24878
                     /locus_tag="VWX69_001045"
     CDS             23967..24878
                     /locus_tag="VWX69_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU9192405.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            24941..26005
                     /locus_tag="VWX69_001046"
     CDS             24941..26005
                     /locus_tag="VWX69_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192406.1"
                     /translation="MKQEWFESNNFVKTTSKNKPEEQAQEVADKAEETIADFDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(26077..26937)
                     /locus_tag="VWX69_001047"
     CDS             complement(26077..26937)
                     /locus_tag="VWX69_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU9192407.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDDSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILV
                     QDFKTLAQEK"
     gene            complement(27059..28045)
                     /locus_tag="VWX69_001048"
     CDS             complement(27059..28045)
                     /locus_tag="VWX69_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU9192408.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(28317..29792)
                     /locus_tag="VWX69_001049"
     CDS             complement(28317..29792)
                     /locus_tag="VWX69_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU9192409.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(30050..30973)
                     /locus_tag="VWX69_001050"
     CDS             complement(30050..30973)
                     /locus_tag="VWX69_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9192410.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(30987..31916)
                     /locus_tag="VWX69_001051"
     CDS             complement(30987..31916)
                     /locus_tag="VWX69_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9192411.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(32235..32456)
                     /locus_tag="VWX69_001052"
     CDS             complement(32235..32456)
                     /locus_tag="VWX69_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192412.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            complement(32410..32670)
                     /locus_tag="VWX69_001053"
     CDS             complement(32410..32670)
                     /locus_tag="VWX69_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192413.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT        10104 a         6998 c         5658 g        10127 t
ORIGIN      
        1 tttatccaag gagattgaga caccttgctt ctaaactgac taattttctt atattcgtta
       61 gtcaatttag tagcaaaatc ttccccaatt aaatgaaaga ttgctaactc taggataaaa
      121 acacttatta atacggtata agtcaaaaaa ctttctggga aaaacttatt gattaaaatg
      181 gggaaactca ttaacagaat cgaatttatg gctagacaga tagatactat tttatttttc
      241 acagaatata gaggtagtga tactattgag tagataaaag ctaaaaaaat aagcaaaaaa
      301 tactccgtgt catttataat cgccctgaat gataaaaata tatacatcca acatacgata
      361 atatgtattt ttcgaatctt atctacatta ttcatcttac tgtcgcagat ataaatccat
      421 cccaaggata agggttcccg ctaatatcac aacctctatt aagagcacca tatccaatac
      481 agtaagctat ttttcctgct gctgcaccaa taagccagcc tccaagacct ccaaccttaa
      541 tatagtttat tagttttttg gttaaaactg cagctccagc taatgctata aaagttcctg
      601 aactcatagc taaagctacg caaattcctt gacaagcacg cttgcttaaa taagctcccc
      661 catcaagata catcatttct tcttcatcaa tcacaacata attatttggt aatacaagtt
      721 ccatttgttt tctcctcctt agttgaaatt gtttcatttg ttttacaaat aggacgaact
      781 taaactatct ttttattact cagtaataat ttccgagatt tcattttatg atactctcta
      841 ttcatacaga aatcaaaatt ttgccttaac caacttgtat aatagaaaaa atctaattga
      901 tttattctga tgagctgtat tctaatttta tcaacctttt cttgccagtt gttattgtta
      961 ctaatagaaa tctcatacag cagtaactcg acaagacctg tacacagaag ggtgttatga
     1021 gaatcttcaa ttttactcag aatatcctca aaaagttcac tatccgttaa aaaggtggat
     1081 tgattcatcg catcatacag ctgaagagac attaagtcag aataactgag atctgatttt
     1141 tgtattttat cctttaacgt atttgtcaaa tcactttcaa acgaatcttc tttttcccat
     1201 ttattttgat tgaaaagaaa ttccgtctta ttaaaaacga gatgattgat atccattata
     1261 gtccaaaaaa atattgtagt aagcataatg atgacaaaag gaatttttaa aataaatact
     1321 aggataatag caatttcaag aataaaactc catataatcc tagatcttaa atcatcaggc
     1381 gacaaacttt tacgatggaa tgaaaaatag ggcgagaacc tcacatttac tttcttcctg
     1441 cctataaaaa taaaaggaaa aatcgtaata agagcttctt tcttgtacaa atctttcaat
     1501 gcgtatagta tgtctaaaac tatttttgat aaaatcaaac tacagaaagc aagactcata
     1561 ctaatcacaa aatcaagggg agattctaga ttcaatagta agttattcac taggacatgc
     1621 aactctagcc acaagacaaa aagagggagc attagtaaga aaacaattag tttacgcatt
     1681 ataacaatta gtaaaattta cgcgtccata aagcatacgt aattcctgca actgaaatac
     1741 ctccaattac agccaatgcc gcattaacag ctgctactga ccctagtatt ggagcgaaag
     1801 cagaaacaac ataagtataa gaatacactc ttgtagacca tattgcagcc cataaaccag
     1861 tttctcttgc ggcaaaccta aatcctgagg aagctctcgc taaacctttt atattatttt
     1921 taaatgtgtt ccagtctccc ccatcaaggt acatcatctc ttcttcatca atcacaacat
     1981 aattatttgg taatacaagt tccatttgtt ttctcctttt tattaagcat ggttaggatg
     2041 gtttcctaac aagtaatcgt cgtctgtgtt tctatcactt agctacctag ataagatatc
     2101 ctttctctac cttatttgtt tttataggtt acctaaggtt taaaaccaat tattgcttga
     2161 aacttaacat ttctaaaatc caatcaagat aggtttcttt atcatagaca atccgcactt
     2221 caactggcat atccttttgg aggacgactg tctcacttcc atgttttaga gttaaggttt
     2281 ctaattctat catgacttta taaagactaa tattgccttc tttcgtttct tgggaaattg
     2341 ttcctgaatc aatctgtctg acttgtccct ttagtgttcc atatttttga ctatttacac
     2401 cagtaatagc aacatcagct tttgctcctt tcgaaacacg agaaatatca ctcgcaagta
     2461 caaaagcttc tacatagtaa cctttttctt tccctgaaac ttctgctatc gtttgcccct
     2521 gctgaataga cattccttgt ttcaaaggta acagataatg cagagtacct tcatttggcg
     2581 ctaatatact atgagcttta tcttgacctg ttgccactcc aagattagcc tcaagctctg
     2641 taatactttt attgttgttt gaacgagcag tacctaactc actaactaat tgagcataaa
     2701 tattataagc ctgagaagtt ggatcattat aggtacggtt catatcctta atattgcttt
     2761 gttgactatc aatctcgcta ttcttagaag taatatttgt ttttaatgct tcgatttttg
     2821 ttgttatttc tgatatctta gtttctaact tagctttgtt atcagctgat gtcgtatctg
     2881 atagagaagg tgagtctcct tgctgttgaa gttgaagcaa ttcattttgt agagcttgca
     2941 agtcggcatc taactgattt ctttcagctg ttattttatt caacttcgta tattcatcct
     3001 gaatctttga atactgggta ccattattat aattttccga atttaactga gataggtagt
     3061 attcaacttt cccataatat tcctgttctt caccagaatt agataaatga ttgtatttct
     3121 catttaatga ttgttcaaat ttttgaaaga tagcttcttt tgcacgtaac ttctccaatt
     3181 gtttatttaa agagctcgct tgtaaacctt cttgcccact tgataacgaa ataatgacat
     3241 ctccagcatt taccatatct ccttctgact tatgtaaagt aactaccttc cctgaaccaa
     3301 ttgctgatag gaactctgta cctgttataa ctgaatttcc attcgctttt acaatatagt
     3361 ttttgggtat ataagctgcg ccaaccaatg caccgcttaa gataatagca gttgaaataa
     3421 tgagaataaa cgcaaaagct ggtggtctct tatcaaagaa aatacgagaa taacgtaatt
     3481 ctgatttatt atataatttc ataggcttac aattggtcta aaaatatcta ctaccatttt
     3541 ttcaggagaa gaattaacat aaactgtata gacaatccca tccgtttgaa tatcattttc
     3601 atagacatat agatccaatt tagaatacgc atactgtaga tactctggac tgtcttcaaa
     3661 acgaacatat aaacaatatg gaacagagat agaatcctgt acatcataaa tgttactgta
     3721 ctgttgagca ttatgagctt gaatataaaa ctcaaaatca gtcgttatta atccatcatc
     3781 atgaatagta gtaccacaac tttttacaat taatggacca aaaatttgtg cttttaacaa
     3841 ctgcaaatgt tgatgaaatt tattaatttc ctgatctaca tcttctactt ttgtatcatg
     3901 taacttttta cagataactg actttagtac cagtttttta ttatctttta cctctaactt
     3961 agccataagt aacctcctct gtatctaaca cagcctgtga ctgaatttgt tgattcactt
     4021 gaacgctctg caaaccaacc attctagcat actttccatt tttcgccatt agttcttcat
     4081 gagtaccata ttccataata gtcccatttt ctaaaaagca tatcttatca catcgaagaa
     4141 ttgtagacag cctgtgggct actacaattg ttgtcttatc cattatttta ttaaagatta
     4201 aatcctgaat aatctgttca ctaaatgaat ctaagttaga ggttgcctca tcaaatatat
     4261 acaaatcagc tttactcagt agtgctcttg caatagccaa tcgttgtttc tctccacccg
     4321 agaaattttg accgccttct tctacaaagg agccataacg attttgaaga cgttgaatcg
     4381 tatcatgaat accaacaata cgacaaactc tcaccatatc ctcatatgta acagaaggat
     4441 taccaatttt tagattatca ataattgtcc ctgtaaagag ttctatggtc tgaggaatgt
     4501 aggaaatttt cttacgtagt ttaccatagt caagatctga taagtcattt tctcctatac
     4561 gaattttccc ctcactcgga tttataaatc ttaataacaa acgaactagc gtactttttc
     4621 ctgctccgct ttctccaaca aaagctattt tttctccttg tttaattcgc aaattaaagt
     4681 ccttgataac aggagggcgt gaaccatagg caaatgttac atctttaaat tcaatgtcat
     4741 cacataaggt gaagtctcta atactataat ccaaggcaat gtcttcacga tctacttcca
     4801 tcaattcttg aagccgacta accgcaacct gtacctcttg aaaggttaac tgcaagccaa
     4861 ctaaattctg aataggttct gtaaaatatt gacttaatgt ctgaaaaacc aagaggtccc
     4921 caatagtcat ttttccatca atgataaata aggcgcccac tcccataaat aataacccac
     4981 ccatggttga ggtcattgaa gatattgtag attgaatatt ctgcaaaaca ccctctttat
     5041 aaccaatttc taaagtatga acaaattttt cttcaatttt gtttaaacgt tgttcctcat
     5101 catgctgaga cttaatggta tcaatgttac gaatagattc aattaactgt gaattaagaa
     5161 gtccatttgc ttccatttgt tcatgattaa tttttttata aggcttttta aaacagtata
     5221 taagaatgat gttaacaata accataaaaa ctaatatcag aaataaagat tgattaatag
     5281 tccaaaggac aaccgcacta ataactgaca aggtgatatc catgactaat gaaatagaga
     5341 ctgacgtaaa cacattcttt atcgtcatcg catcttgaaa tcttgttaaa acatcaccaa
     5401 ctctacgact tccaaaaaaa ctataaggaa gatgaataat atggtcataa tatcccatta
     5461 aaaccggtat atcaattttt cgagatagaa acaaaagaac gtgctgacga aatgcagata
     5521 gaagagtctg taagaacgac actattccaa atactatcaa aaacatatac agactatttt
     5581 ttaaagcata tggaatcacc tcgtccatga taacttttga aaagagactc gataaaatac
     5641 caatgatact taaaacaaag gaagctaata tgactgtact aatcaatcct ttttgattaa
     5701 aaattaacct tccaaataaa tcaagaagtc cttttccctt tagtttccct ctttcaaaat
     5761 ccgaatttgg aaccataaaa agagtaatac cttgataaat ttctcccagt tcgtcacttg
     5821 acatcttgcg tatgccacta gcagggtctg ctacgtagaa cttactattc cttttgatac
     5881 tatgtagtac cacaaaatga ttttgaccta aatcattctt aacttgaaga atcgcaggaa
     5941 atgttaattt tggagtcaaa tcttccagtg ctactcgaac agcttttact gtaaaattca
     6001 acttattcag acctgaaaca ataccactga cagtcgttcc atacatgtct gtaccaataa
     6061 tttccctaat cttcatgatt gatagttcct ttttgtaaga taaaagaact gttgaaacaa
     6121 ctgccgcagc acaatctgac tggtcatgtt gcatcgtaca aggatatttt tttaacatag
     6181 aaatactcaa ttctttagaa ttaatctaac ttttctttga tgtcacccaa acctcaatca
     6241 ctgcccagta gttcttgaat taatttattt tcaaccgtat cattctttgt tcttgatatc
     6301 tttccaagca ttgtagtaca gcagattttt gcccaaggac tgagcctcct ttaacaactc
     6361 aaactccctt acattatatc ggccagcccc atggaaagat tatagccaga ctaatcaatg
     6421 atataataca tactagaata caaaatattt ttttattcat actttttctc ctatctttat
     6481 tttctaccta catagtacct cttattaagc tcattttaaa attacgttaa cttttttcac
     6541 aaatttattt cgactttctt ttttactttt tacattgcta tgatacaata tttttaacaa
     6601 aattttattg tttgttaact tttttcacga aaaggagaaa atcatgcgtt atgatttcgg
     6661 aaaggtctat aaagaaatac gtgagtcaaa ggggctgacc caagaagagg tctgtggggg
     6721 tgttctctca agaaccagct tatcaaaaat cgaaagtggc aagacaaccc caaaatatga
     6781 aaatatggaa tttcttctcc gtcaaatcaa tatgagtttt gaagagtttg aatatatctg
     6841 tcaactttat caaccaagtc aacgcacaga gattatgcaa acctatctca atatgcgttc
     6901 cattatcggg accagcgatc ttgtcaattt atttcaaaaa tgccaagact acctcaagac
     6961 ccaccacgat ctccctatag aagaaatcag agatatgctt gaagttgtta tttatctccg
     7021 tcaacacggg gcaggggaac tatcaaaaca cgcagaacag gttgtcaaaa aactttggaa
     7081 aaaaattgaa aaacaagata catggtatga gagtgatcta aaaatcctca ataccattct
     7141 tttcagtttt cccattgaat acctccatct catcactgga aaaatattgc aacgcctaga
     7201 agtctataaa aactatcaac atttatatga cttgcgaatg acaattctat taaacctttc
     7261 cacactctat ctatacaatc aagataaaaa catgtgtaag caaatctgct acactttact
     7321 ggaggacgcc aagaataaga aaagctacga taggctggct atctgctatg tccgtattgg
     7381 gatttgtagg gatgatgcga aacttatcca aaaagggttc tcccttctgg agctaaccga
     7441 ggaaacttct atactgtctc atctcaaaaa agaagtagag atctattacc aagcgaagga
     7501 aagataaaaa agccgaggga tttcctcgac tctttacata ttatttgttc gttagttctt
     7561 aataccagcc attgttaaac cagaagtttt tagctctgcc aagccacata gtgtgtttac
     7621 tactatgtgt ccatgtcacc atgaatcgcc gaacgattta acgagaaagt atgactttta
     7681 cgtttatccc aactcaatta tgacattttt ttcaaaagtc aatatatctc actttttcaa
     7741 cgacaagaaa gaggctgcca atcgaccaac ctcttattct gaacccatca ctccatcact
     7801 ttttagcttc attcgctttc ttagcgactg caatctggta ttcgacttgg tcaaaccctg
     7861 tgcctcccaa ggaatttcgt ctttgaacag cagttttagg ttgcaagtag acatagatat
     7921 cctcggtaat gagagaatga taggtttgta attcctccaa agtccaatct tgaagatttt
     7981 tagcagactt gatagagtct agcactaatc ttcccacaac ctcatgagct tctctaaatg
     8041 gcaagccttt ccctgccaaa taatctgcca actcagttgc atttgaaaag tccttctctg
     8101 ttgattcttg cattttttcc ttgtttacct gcaaactaga taacatacct gccaacacat
     8161 cgagggaatt taaaatcgtt tcgaccgtat caaacattcc ttccttatct tcttgcaaat
     8221 ccttattata agctaaaggc aaggacttca tgactgtcaa cagtccaaac aaatgcccat
     8281 aaactctgcc agtctttcct cgaatcaact cagccatatc tggatttttc ttttggggca
     8341 taatagagga acctgttgta aacgtatctg acaaggtaat gaattggtac tcaaaactac
     8401 accaattgat catttcttcg caaaaacgac tcatatgcat catgagtatg ctggcatttg
     8461 atagaaattc taagataaaa tcgcggtcac taacagcatc caaagaattt gtataaggtt
     8521 gcttaaactc cagcaaatcg ctagacaatt ggcgatcaat ggggaaagtc gttcctgcca
     8581 aagctgccgc acctaaaggg cataggtctg tatgcttctg gttaaattca aaacgttcac
     8641 tgtctctttg aaacatattg tagtaagcca tcaggtggta ggcaaaacta ataggctggg
     8701 catgttgcag atgggtatag cccggcatga tcgtcgccac atgattttcc gccaagtcta
     8761 ataaaacacc cttaagatga gccagtttat ctaggacata gcctagttgt tccttgagat
     8821 acaagtgcat atctgtcgca acttggtcat ttcgagaacg agccgtatgt aacttccctg
     8881 caaggggacc aattttttct gtcagcaaca cttccatatt catatgaata tcttcgtttg
     8941 cgatatcaaa gtcaagttga cctgcctcta gctcttctaa aagctctttc aagcctactt
     9001 gaatcttttc tgactcctcc aaactcaaaa tgcccgtctg acccaacatc tgaacgtggg
     9061 ctaaagaacc aatcacatca aatttagcta atttctggtc aaaagatata ctcgcaccaa
     9121 agcgctctac ccagtcttcg acagtacctt caaagcgacc accccataat tttgtattct
     9181 tagccatatc acatccacct ctctatccaa tcgtcctatt tggcgctttt ttgaacctca
     9241 gaatgaacct tggttggaag tccccataac tcaataaagc caacagccgc atcttggtca
     9301 aaggtatctg cactagtata cgtcgccaaa ttttcatcgt aaagagaatt tggtgatttc
     9361 cgagccacga cctgagcgct cccccttata cagtttgact tttgcagtcc cattgacaac
     9421 tttttgagtc tctttaatat aagcaatcaa ggcttgtgta gccgaactaa accacaaagc
     9481 attataaatg agatttgata attcattttc tatgattggt ttaaaatgag ccacttctct
     9541 cacaagcgtc aagtcctcaa tttccttatg agctgtcagc agggtcactg cacctggaca
     9601 ctcatagatt tctcttgatt taatcccaac caagcgattt tccacgtggt caatccgtcc
     9661 aaccccatgt tttccagcta tttcattgag tttttgaatc aaatctgcca attttaacac
     9721 ttctccattg agggaaactg gaacaccttc actaaactca atctcaatgt attctggcat
     9781 atctggagct tgctctggag aagttgtgat gccaaaggct tcttctggag cctgattcca
     9841 tggattttcc aaaataccac actcattggc acgtccccaa agattttggt cgacagagta
     9901 gggattgtca aggtcagcag gaacaggcac cccatttttc ttggcataat aaatttcttc
     9961 ctcccgagac catttccatt cacgaactgg agcaatcact tttaaattgg gatccaaggc
    10021 tgcaatcgat acttcaaaac gtacttggtc attcccctta ccggtacaac catgagcaat
    10081 tgtagtcgct cctatctgat gcgctatttc aaccaatttt ttagaaatca gagggcggct
    10141 caaggcagat accaagggat acttttgttc ataataggca tgtgactgat gagccactag
    10201 cacataatct gtagcaaatt cgtccttaac atcaatgaca taagattcta ctgccccaac
    10261 cttaagagcc ttatcatgga tgaaatctaa gtctttccct tcacccacat ccatacaaac
    10321 tgaaacaaca tcatagtctt tctttaacca ggtaatagca actgatgtgt ccaaaccgcc
    10381 agaataggcc aaaattactt tttctttact catgttcttt tccttctttc tatttttcaa
    10441 tggatgcttt aaaggcatcc tcaatgagtt tgtctaattc cccagactcc ttcaactttt
    10501 gaatagtttt atcgactgcc tctttcaatt ccttactatc ttttttcatg gctaccgagt
    10561 aggaatcatc ttgctctttt tcaaaattga ggtctgcgat tgctaaatca ggattatttt
    10621 ccacaaagcc cttggcaact ggttcttcaa agataacggc atccacttgt cctgatttta
    10681 aatctgtgat taaattccca tttttaggca gagatacgag ggaagaattt tgtagcaaat
    10741 ctttcgccat cgtctcttga atcgaacctt tctgggctcc gaccttcttc tgcgctaagt
    10801 cgttgacaga ctgataagtg actaaatcag attttttgac aatgagttta ttttttgcag
    10861 tatagtaggg aatggaaaag tcaaacacct tgctccgttc atctgtctta gaaacacctg
    10921 atatggcaag atcagctttt cctgattgaa cactagccag tacattgtca aaactcatgg
    10981 gagatagttc caattcgaca cctagttctg ttgcgatagc cttggctaat tcgatatctg
    11041 aacccacaat ctgatttttc ccatcaacca ctttttggta ttcaaatgga gcaaaatctg
    11101 gattgagggc tacaaccaat tttcctttgg acttgatggc ttcaattcca gccgattgat
    11161 tgttactaca agcaaatagt agggggagca tcactaaacc aaacatcgtc atcaacacct
    11221 tcttcatctt attcataaca aagcctcctt tatgtttatt ccttttgttt gtataaataa
    11281 tacacctatc ttcatccttt gtcaagccta aattgtaatt tttttcaatt taaaacagaa
    11341 aaacctagga aaattacata aaaatgtcat tcctaggcgt atttatgcta ttcctctctg
    11401 gaaaatatga gtattcagtc agtcaaaaga agctgaacga actcattttc cctcgcccaa
    11461 ttcaataatc cgatgacatt gttgggctac ataagcatcg tgggtcacaa taatgactgt
    11521 tttcccttct cgattcatct ctaagagaaa cttcaagacc aaatctctat tttcaggatc
    11581 cagcgaacct gtaggttcat cggctaaaat cagctggctg ggttttaaga tggctctagc
    11641 aactgcaatt cgttgttgtt cgccaccaga caactcggag accttttgat gcaaagtagc
    11701 tgacaaacct actctctcta aaatctcttc cacctttttg agcttatctt tcttagacaa
    11761 ttttacatat ttcagcgcca gcataagatt gtactcgacc gtttcatcat caatcagggc
    11821 aaaattttga aacagataag agatatgttc acggattatt gtttgcgact tagcagaatt
    11881 gaccgctaga tttgtctgac caaaaatctc ataccgtccg ctataatcac catctatcaa
    11941 acccaataaa tttaacaagg tcgacttccc actaccactc ttaccaacaa tggcaaccaa
    12001 atccccctga tcaatcctga gagacaagcg atccaaaatc actttccccc caatggtttt
    12061 ggtaatattt tccaactcaa tcataagatg ccccctttca ataactctac tagacttctt
    12121 ttctccatcc tagaagccaa ggctagcaca aatagtatat ccaaacatgt aaagcctgca
    12181 aacagcagga gtggcaagaa cgcatgggca aagaaaatca agactagaag agggagacta
    12241 tagcccagca agagcagaac gaggagagga cggtagcgat cgaccagttt ccaccccata
    12301 aacttcttgg taataatatc cctgcgcttc aataagaaag ttattactag taagaagtag
    12361 gaaatcatca tgctaaagag accaaacaaa gcaaagagta ggttaaaatt ccgaacagca
    12421 tctcgataag aatccacttt ctcttgttga atggcttgaa tagatgaaaa ttttaaataa
    12481 tttccatctg acaatttctc aactaactct gtaatctctt tttgatgttg aaccgtattt
    12541 tcaattttaa tcggattatt taagccagtt gttgacaggg aggctttctc atcccacatc
    12601 atatcagaat cattgaccaa gctaataatt ggattggaga gattttcctt tcgcttatca
    12661 ctatatggga aaaatgacca atctccttca taataggcaa tctcgacatc catctcctct
    12721 atcgttcgtt tttgctgctc ttcatacttc atcgaatgaa aggcaattaa cttccccaag
    12781 agctgatttt tatcttcttc acctttcgta cttgctggca tcaaaataac ttttttaata
    12841 ccagtatctg gtagcttgaa tcccttgctc tttagaaaat tgcgattggc atagtaaaca
    12901 tccaccgtat ctgttaactg atattgctga atctgttctg attggacaaa attttttaca
    12961 ggaagactgc tactctgcac atagcccgcc tgcgtttttt ctactaaatc ctgataaaat
    13021 cgatagaaat aatccaatgc cttccctgag cctgccaact gctcttgcca caagttgtca
    13081 ttgagttgga aagtttctaa ggtcagataa tttccttggc tgatccactg tttctggtaa
    13141 tccaactctt tgttttcttg ctccaaactt tttcctaccc caactagcaa gactgtcagt
    13201 aaaatggtag ttccaatttt catcaaataa ttaaagagta gaccaaattt gaaagatgaa
    13261 aaacctttca gcagagagct gattgtcatt ttttggatta agaggtaagt caaccaactg
    13321 ataaagagat aaagctgcaa cagcaaaaaa tgagacaacc acagcatagg aaacaaatct
    13381 tttggcttat aatcaagcaa gaaaaacacg cctagattga tcacaagagc cccacctagg
    13441 aggaggtaaa ggttgccttt tacaacatca gctaaaacag ccctatcttg aaaaccaagt
    13501 aatttttgta ccccaactcg tttcatctcc atcatcggtt gatacactgt cactaacaca
    13561 agaagcaaaa tagccaagac aaaaacaatg gcagataaaa gcaaatctcg atttatgact
    13621 tccactgcac ttttgtaggt cggctctagc aaggtagcct ggtctatctt gaaaaaatcg
    13681 ctccatttct gtacaatcct atccttgtcc atctcttgtg tagaagttat cgtatagcga
    13741 ccatttaaac tacgagatgt atccttgata taggtttgaa aagtcataag ctgaataggt
    13801 ttggctttta gaaaggtcgg aatcgtacca agtttattgg aaatttcttt attactatag
    13861 actccttcac catctgtggt aaaatcaaga gaagaaatcc caaactcttg gtaggggaag
    13921 gtatctttat caaaaacacc agacttgacc acctcatcgc cattatctac tttgataata
    13981 gagaccttgt cttggcttgc aacctcttca aaaaactgga gaatcgtttc tgtcggttta
    14041 gtgacatctt tcaagtacaa gtcaaatgaa taagttgtct tgcccatctc ctgaatccgc
    14101 actatttctc gtgtaacatt tacattcagg acaaaaaacg tagtacacag caagagcagg
    14161 agcatacaaa gatgactgat ttttttcata gagatacctc ccgtgaagaa actccctctc
    14221 caaaagggga gggagaattt taattaaaat ccatagaaat attccattcc cgttggtggg
    14281 aatttgaaga ttgaagcccg agcccacgcc tcagcttctg cacgatcctt agagaattta
    14341 tttccatctt taacagttgc tgtatgagag cgagtagaat gtaaataatc agaataacca
    14401 aaatttcctg accatcctac tccatagttc cattgaccac catcaaccca tactgccaaa
    14461 acacttgtag aagcaagtat actacatacc attaaagatg caacactaat tttctcatga
    14521 tttatttctc ctattatcga gagctattcc gtagaaacag ctatagtaat ttatcaacaa
    14581 gtatcgtagt ccattggact caccttcctt ctatctcatt tcatttttaa acaacgaact
    14641 tactcttaac taggagaata gttctcttct gtatcaggtc tttgaacaac cagagtagta
    14701 ttaatcacac tctaactatt actcaagaat cagcccaata aacaatatgg atagcgcttt
    14761 caaattttta aactctatcc catcctttta tctatattat gagcgaaaat ataataactg
    14821 tcaagtaatc gaagtgaatt ttataaaaaa aattacaagc caaatttgca aagtttacaa
    14881 taagccgcta gggcaatcgt ctatcagaat gtccgtttat ttgtcaataa tccgagaaaa
    14941 tcttgcaacg cttagaagtc tataaaaact atcaacattt atatgacttg cgaatagcaa
    15001 tcctgctcaa cctttccaca ctctatctat acaatcaaga taaaaacatg tgtaagcaaa
    15061 tctgctatac tttactggag gacgccaaga ataagaaaag ctacgatagg ctggctatct
    15121 gctatgtccg tattgggatt tgtacagacg attctaaact tatccaaaaa gggttctccc
    15181 ttctggagct aaccgaggaa acttctatgc tgtctcatct caaaaaagaa gtagagatct
    15241 attaccaagc gaaggaaaga taaaaaagcc gagggatttc ctcgactctt tacatattat
    15301 ttgttcgtta gttcttaata ccagccgttg ttaagccaga agtttttagc agctgtccat
    15361 gaaccgtaac gtcctgcaac gtaggcatct gctacacgtt cttggttttc agctgagtag
    15421 tcaccgttca ggtatgaatc tgttaattgg taacgtccga tataacgtcc atttgtagct
    15481 gtatagctac cacctgattc tttttgagca atccattctt tggcttctgc ttcagatccg
    15541 cttacagttg aaacaactgt ttcacttact actggagttt ctgctactgg agctgaaaca
    15601 gtttcatctt gagcggctgg tgccgcataa gtagctggcg ctggtgttgc aacaggcgct
    15661 acagggccat cgataaccaa ctcttgacca acataaatca aatgaatgtt atcaatgtgg
    15721 ttgttttctg ccaatttttc aactgttgtg ttgtgagttt cagcgatttc tgaaagtgta
    15781 tcaccttctt taacagtgta agttgatgat tcttgagcag atacaaatga tggagcaaat
    15841 actgcaaaca aggcagctac tcctgcaaga gttgctttaa tctttttagt tattgatttc
    15901 atattcgaaa attctccttc tttctatagt tctatcatac cctttaaata ttaccgtttc
    15961 ttgacacttt tatgtagaaa tattacaaaa ttatttttta tttccctaaa taaggtgttt
    16021 tttgtcataa aagatactat ttttatgcta tttgaggtat tagaaaggtt ttcatccaca
    16081 attaaagcca agcccctcat tctttgatat aatagagata agaattttta taaggggaaa
    16141 ctgatgaaat cacttcgttt tcaatctgtc tttgatatca tcggaccagt tatgattggc
    16201 ccatctagta gccatactgc tggtgctgtt cgtattggga agattgtctc ttccattttt
    16261 gatgatactc cgacagaagt tgaattccaa ctttttaact catttgccaa gacctatcgt
    16321 ggtcacggaa cagacctagc ccttgttgca ggtattttgg gaatggatac agatgatcct
    16381 gaaattccaa atagtctgga aattgcccac aagcgtggta tcaagattgt ctggaccatt
    16441 cagaaagaca gcaatgcccc tcaccctaac accactaaaa ttactgttaa aaatgcccac
    16501 aagaccatca gcgtgactgg tatttctatc ggtggaggaa atattcaggt aaccgaactc
    16561 aatggttttg ccgtctctct caatatgaat acaccgacta tcatcatcgt tcatcaagat
    16621 attccaggta tgattgccct tgttacagag gcgctttccc gctatggtat caatatcgcc
    16681 cagatgaatg tcactcgtga aaaagctggt gaaaaagcca ttatgattat cgaagttgac
    16741 agtcgcaact gtgatgaggc tatcgaagaa attcgaaaaa tccctcatct ccacaatgtc
    16801 aatttcttta aataggagga agcatgtttt attctatcaa agaattggtc gagcaagcag
    16861 atctggactt tcaaggaaat gtcgcagaac tcatgattac aacagagttt gaattgaccg
    16921 gtcgcgaacg tgaagaagtc ttccttctca tggaacgcaa tctggaagtt atgaaagcct
    16981 ctgtccaact tggcctcaat gaaaataaat ctcgtagtgg cctgacaggt ggagatgctg
    17041 ccaaattgga tcactacatc gaaaacggaa aaactttatc agattacacg attctctctg
    17101 ctgcccgaaa tgctatcgca gtcaatgaac acaatgctaa aatgggcttg gtctgcgcta
    17161 ctcctaccgc aggaagtgcc ggttgtctcc cttccgttct cactgctgct attgaaaaat
    17221 tagacctcag ccacgagcaa caattggatt tcctctttgc tgctggtgcc tttggactag
    17281 tcatcgcaaa caatgcctcc atctcaggtg ctgagggtgg gtgtcaagct gaagttggtt
    17341 cagcctctgc tatgagtgct gccgccttga ctctggctgc aggtggaaca ccttatcagg
    17401 ccagtcaagc tattgccttt gtcattaaaa atatgctagg cctcatctgt gaccctgttg
    17461 caggtttggt cgaagttccc tgtgtcaaac gtaatgccat gggagctagc tttgctttca
    17521 tcgcagcaga catggccttg gcaggtatag aatctaaaat ccctgtggat gaagtgatcg
    17581 atgccatgta ccaagtagga gcaagcatgc caactgcctt tcgtgaaaca gctgaaggtg
    17641 gactcgctac cacccctact ggtcgtcgcc tccaaaaaga aattttcgga gaataagctt
    17701 atcaaatagg agaaaccatg acctctatca cagcgatttt tttcgatttg gatggaaccc
    17761 tcgttgatag ttctatcggg attcacaatg cctttaccta tacctttaaa gagctggggg
    17821 tgcctagccc tgatgccaaa actattcgtg gttttatggg accacctctc gaaagtagtt
    17881 ttgcgacctg cctgtccaaa gaccaaattt ctgaagccat gcagatatat cgttcttact
    17941 ataaggcaaa aggcatctat gaagctcaac tctttcctca gattatagac ttgcttgagg
    18001 agttatcgag cagttatcca ctctacatca ccacgacaaa gaatacatct actgctcaag
    18061 acatggccaa aaacttggaa atccatcatt tctttgatgg catttatggt tctagccctg
    18121 aagcacccca taaggcagat gtcattcacc aagccttaca gacacatcaa ctagcaccag
    18181 aacaagccat catcatcgga gataccaagt ttgatatgct gggagctcga gaaacaggta
    18241 ttcagaaatt ggccgtcact tggggatttg gagagcaagc agatctacta aactatcaac
    18301 ctgattatat cgctcacaaa cccttagaag ttttggcgta ttttcaatag catagactgg
    18361 gcgacaactc tatttcagaa gaaaatgaag taatactcaa tgaaaatcaa agagcaaact
    18421 aggaaactag ctgcgggctg ctcaaaacac tgttttaagg ttgtagatgg aactgacgaa
    18481 gtcagctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag taacatatac
    18541 atacggcaag gcgacgttga cgtggtttga agagattttc gaagagtata agtctctaca
    18601 taataaaacg catattacca aggttgtgta acttgatact atgcgttttt cttttttatt
    18661 caatgtgggt tgtttgatta gcaaaggcga taatagcttg cttcaactca tctccactga
    18721 gagtgcggaa ctctccaatc ttttgattga tggattctaa aggcatgaca ttaaccttac
    18781 caacgaaaat cttatccata acttgattat caacgagttc ggttgatacc aagagttctt
    18841 cgtagagttt ttcacctggg cggattccaa cttcaacgat tggaatttca ctttcagtgt
    18901 ggccacttag aagcaccatc ttcttggcca agtcataaat cttgactggt ttgcccatat
    18961 caaggataaa gacttcccca tctttggcat aagcaccagc atggataacc agacggctag
    19021 cttctggaat ggtcataaag taacgggtca tgcggaagtc tgtcaccgtt acaggcccac
    19081 cttcagcaat ctgacgttca aagactggaa tgacactacc acggctacca agaacattcc
    19141 caaaacgaac tgcacagtag gttgattggc tacgttggtt aaagccagtg acaatcaact
    19201 ccgccacgcg cttggttgct cccataacat ttggtggatt gactgcctta tctgtcgaaa
    19261 tcataaccat cttagacact ttagcttcat caacagcctt agcaacattg taagttccac
    19321 ggatattgtt tttgaaggct tcttttggat tgcgctccat cataggaaca tgcttgtggg
    19381 ctgccgcatg ataaacaata gcaggtttgt actgctcaaa gacttgcaac aaacgatcat
    19441 agtcttgaat gtccgcaatc acaggtacat aatcaatccc ttggaactta cgaatcaatt
    19501 catgataaac aaggtagatt gagttttccc catgaccgag taagacaatg cgttcaggat
    19561 tgaagcgact aacttgacga cagatttcag aaccgattga acctccagct cctgtgacta
    19621 agatggtctt acctgtcagt tctgcaccca gacgcgattc gtcaagacgg atttcctgac
    19681 gacccaaaag gtccgtaata tcaatttttt ggaagccagt acctgcttgg tgaaggccct
    19741 gaacaacagt ttcaacctta ggcatcttgt aacatttgac acccagctta ttacacatct
    19801 gcaagatacg ctcatattct gacggatcca gcgacggaat cgcaacgatg acacgctcga
    19861 tttgatggcg tttggctaat tcaggcagat tgtcataaga gcccaaaaca ggaataccac
    19921 caagtttttg accctttttc ttagaatcct tatccaaaat accgaccagt tctaattcac
    19981 tggttggatg ttggtaacta tccataaaga gagccccacc atcaccggca ccaatcaaga
    20041 aggtccgacg gtgttctcca tcaccactac cttttttgcg tctggagtag attaactgcc
    20101 aagtaatccg tggcaataaa atcaagaagg tactcaacaa gataaagaga atgatgaaac
    20161 ggatggagaa gagtggcaag aaggcataac agatactata tgacaagaca ctgctagcag
    20221 tcacaccaaa aaagattttc atgaaatccg taatcttgct gtaacgacta atgctcgcgt
    20281 tcaaccccca aaaaccaatc atcaattgat agaacaagaa ggccaaactc gtatagataa
    20341 tgtagtcaac aggtgctgga ttaatcagcc cataaaataa aatataagat acaattatgg
    20401 aaaccaccat actgaaaata tcaaatattc cccagaaaac ctgcttttgt tgtttattta
    20461 aaatttccac cagatcaatc acataatctg ttagtttttt attcatagaa atctactcct
    20521 ccttaaaaga gttttactat attgttatta tagcatattt ttatttattt ggcttatttt
    20581 atccaaataa attattgttc tcttgtactc cttcttccat ttaaatcctc taattaaacc
    20641 tacaatcgtc ccaaggccat aagcaaagtg aatggaaaat aaaagaaagg gcatcacaat
    20701 tagaaatcca tttttatgtt ttaataaagt cagcaaagtg agtaatgaca aaagtagaaa
    20761 ataggcacct aatagtaaag ttatgaatac gaatgtgatc ggtaacaatg ctagactaaa
    20821 cacaagactc aaaacaaata aacaaggaac atagtgaaat aatgataaac acttaaactg
    20881 aacatgactt gtcaagccaa tccacaaacc atttgaatac ttttgatgca gcattttctt
    20941 gaatgttggt cgaatatact gataagatag aatacttggg ctatagcgga ttttataacc
    21001 atgttctcga attctataat gaatatcatt atcttcagtt cggccaagtt gctcatttac
    21061 taaaccaacc ttctggaaaa cctctcgttt atacatccca tgaaaaatag aagaaacata
    21121 tctatcctcg gaactatttc gataattggc aatgctactg ccaaacatat tttcctcaac
    21181 aagatgcaag gtctctgccc attttccttt tccttcgaca atcgtcggtc taggcccccc
    21241 acagacaaat tcaccttgtt gaataatagc cacattgttc attacaaaac tctcagtaac
    21301 ttttgaatga gcatcaattt ttaaaataag gtcccctaca gaatgtttaa ctcccaggtt
    21361 aaaaccacta gcttgatttt tcttaggatt gttatacaat ctaattgagt taaactctgt
    21421 atcttccttt ataaattgct gaatgatagc tgtggtccca tctgtggaca tagcatttat
    21481 aaatagaatt tcaacattct ctttaggata ggtttgattt tttaagtctt caattagacc
    21541 aggcagatat ttttcttcat tgtatgcact gattacaatg gatacgagaa gactttcaac
    21601 attttgagtc actactactc tcctgaattt ttccttccac cattctatca taattttcaa
    21661 gactttccca tttttatctt gaaagccaga aaccttactt gacattatag tgaaaaagcc
    21721 ttaaaataag ctgttattaa aatcagctag aagaggtatt atatgaaaaa gcaatcactc
    21781 ttttttgttc caggtattat cctgattggt gtttccttgc gaactccttt tactgtttta
    21841 cccattattt tgggaaatat ttcgcaaggt ctggaggtag aagttagttc gcttggtgtc
    21901 ttgaccagcc tgcctctcct tatgtttacc ctcttttcac cattttctac ccgactggct
    21961 cagaaaatcg gcttggagca tctcttcacc tacagcctct tcttcttgac catcggctca
    22021 ctcattcgac taatcaatct gcccctgctc tatctaggaa ccttgatggt tggggcaagt
    22081 gtcgcagtca tcaatgtcct gcttcctagt cttatccaag ccaatcaacc aaagaaaatt
    22141 ggttttctga ccaccttata tgtaacgtct atggggattg caacggctct ggcttcctat
    22201 ctagctgtgc ccattacaca agccagttct tggaaaggac ttatcctcct cctcacgtta
    22261 ctctgtctag caactttttt ggtctggctc ccaaatcacc gctataatca tagactagct
    22321 ccacaaacca aacaaaaaag tcaaataaag gtcatgcgta ataaacaggt ttgggcaatt
    22381 attatctttt caggttttca atccttgatc ttttacaccg tcatgacctg gttacctacc
    22441 atgtctatcc atgcaggtct atccagtcac gaagctggct tgctgacttc tatcttatct
    22501 ctgattagca ttcctttttc aatgaccatc ccaagcctga caaccagttt atctactcgc
    22561 aaccgtcagc tcatgctcac tctggtttca ctagctggtg tggtcggcat ttccatgctc
    22621 tttttcccaa tcaataattt catttactgg cttaccatcc atctcctcat cggaaccgca
    22681 accagcgccc tcttccctta tctcatggtc aacttttcac tcaagacaag cgcccctgaa
    22741 aagacagccc aattgtccgg cctatctcaa acaggaggct atatcctagc agcctttggg
    22801 ccaaccctct ttggttacag ttttgacctg ttccactctt gggtaccagc tgtagctgcc
    22861 ctcttgctca tctatatcct gatgactgtg gccctcttta cagtggacag agcggataag
    22921 atcctttaaa cttctagttt tagctagaag ttttttatat ataaaaattt tacacatttc
    22981 tcttgacagg gctttctttt agatgtacaa tgtatgtgta gaaaaattat atataaaaat
    23041 cttacacatt agaaaaggag gtttcccatg tactttccaa catcctctgc cttgattgaa
    23101 tttctcatct tggctgtact ggagcagggt gattcttatg gttatgagat tagccaaacc
    23161 attaagctga tcgctaatat caaagaatcc acactctatc ccattctcaa aaaattggaa
    23221 ggcaatagct ttctgacaac ctattctaga gagttccaag gtcgcatgcg caaatactac
    23281 tccttgacaa acggtggtat agagcagctc ttgaccctaa aagatgaatg gacactctat
    23341 acagacacca tcaatggcat catagaaggg agtatccgcc atgacaagaa ctgaatacct
    23401 gactcagcta gaactctatc tcaagaaact acctgaagct gaccgtatcg aagccatgga
    23461 ctatttcaga gagctctttg acgatgctgg agtcgaagga gaagaagaac tcatcgctag
    23521 tttgggaact cccaaagaag cggcccacga agttctatcc aatcttctcg ataaaaaaat
    23581 caatgaagca cccgctcaaa aaaataaccg acaaatttta catatcgcct tgttagccct
    23641 ccttgcagca cctatcggca ttcctctggg aatcgccatc ctcgtgaccc tgttcgcaat
    23701 ccttgtagcc gctttgactg tcattctggc tttctttgca gtttccatac tgggtatcat
    23761 cggcggattc ctatttttag ttgaaagttt cactgtcctc gcccaagcca aatcagcctt
    23821 tatcttgatt tttggttctg gtttactggc tatcggtgct tcttcgctag ttttacttgg
    23881 catttcctat gtaactcgct tcttcggtct actcattgtt cgtctggtac aatttgttct
    23941 taaaaaagga aagagaggta accagcatgc gtaaatggac aaaaggattt ctcatctttg
    24001 gtgtggtgac taccgttatc ggctttatcc tgctttttgt aggtatccaa tctgacggga
    24061 ttaagagcct actttccatg tccaaagaac ctgtctatga tagccgtacg gaaaagctaa
    24121 cctttggcaa ggaagtcgaa aacctagaaa ttactctcca ccaacacacg ctcaccatca
    24181 cagactcttt cgatgatcaa atccacattt cttaccatcc atctctttct gctcaccatg
    24241 atcttatcac caatcagaac gatagaactc tgagtctcac tgataagaaa ctgtctgaaa
    24301 ctccgtttct ctcttctgga attggtggga ttcttcatat cgcaagtagc tactctagtc
    24361 gttttgaaga agttattctc cgactaccaa aagggagaac tctaaaaggg atcaacatct
    24421 cagccaatcg cggacaaacc accatcataa atgctagcct tgaaaatgcg accctcaata
    24481 caaacagcta tatcctccga attgaaggaa gtcgtatcaa aaacagtaaa ctcacaacac
    24541 ccaatatcgt taatatcttt gatacagttc ttacagatag tcagctagag tcaacagaga
    24601 atcacttcca cgctgaaaat atccaagtcc atggtaaggt tgaactgact gccaaagatt
    24661 atctcagaat catcctagac cagaaagaaa gccaacgaat taactgggac atctcaagca
    24721 actatggttc tatcttccaa ttcacaagag aaaagcctga atcaagaggt acggaattaa
    24781 gcaaccctta caaaactgaa aaaaccgatg tcaaggatca actcattgcg agatctgatg
    24841 ataatattga tctaatatcc acaccaagca gacgttgaca aaaacgctta catctgctac
    24901 tatggaagca tatttatcta actaaaaagg aggttctacc atgaaacaag aatggtttga
    24961 aagtaataat tttgtaaaaa caacaagcaa gaacaagcct gaagagcaag ctcaagaggt
    25021 tgcagacaag gctgaagaaa cgatagccga tttcgataca ccaattgaaa aaaatactca
    25081 gttagaggag gaagtctctc aagctgaagt cgaactggaa agccagcaag aagagaaaat
    25141 tgaaactcct gaaggcggtg aagcgagaac agaaatagaa gaaaagaagg catctaattc
    25201 tactgaagaa gagccagacc tttctaaaga aacagaaaaa gtcactatag ctgaagagag
    25261 ccaagaagct cttcctcagc aaaaagcaac cacgaaagag ccacttctta tcagtaaatc
    25321 tttagaaagt ccttatatcc ccgaccaagc tccaaaatct agggataaat ggaaagagca
    25381 agtgcttgat ttttggtctt ggctagtgga agcgatcaaa tctcctacaa gtaagttgga
    25441 aacaagtatc acacacagtt acacagcctt tctcttgctc attctgtttt ctgcatcttc
    25501 ctttttcttt agtatctatc acatcaaaca tgcttactat ggacatatag caagcattaa
    25561 cagtcgcttc cctgagcagc tagctccttt aactcttttt tctatcatct ctatcctagt
    25621 agcgacaaca ctcttcttct tttcattcct cttgggtagt ttcgttgtga gacgatttat
    25681 ccaccaggaa aaggactgga cgctagacaa ggttctccaa caatatagtc aactcttggc
    25741 aattccaatc ttcctcactg ctattgctag tttctttgct ttctttgata gcctacgatt
    25801 tacagctctc ttgtgtgtga ttagcattgg aatcattctg cttgccagtc tccatatcat
    25861 tacaagacca agtcaagcaa gtgaaaccga ctccttctat caattattct tgtctgtcct
    25921 tgtgaacgga gttattatcc tcctcttctt tgtagctgaa gtggcactga ttggagatta
    25981 tcttcgtatc ttggcctttc tttaaaattc aatcctgtca tccttggcag gattttttct
    26041 atgtcaaaaa agcaagtcga ttgacctgct tctgctttac ttttcttgtg ctaatgtttt
    26101 aaaatcttgt actaggatgg gttgtatttc tatttgattg gcgtctagtt ggtggtaaaa
    26161 agatgggggt aatacctcta agaattttgc atagtccaag cgagctatgg attcatagtc
    26221 ttctggttta gagtcgtctc ctgtgatttg aaccaagtca atctcccact ggacttcctt
    26281 atccaccaat tgctcaatat aggctgcagg aacaaacggt tctctcggta aaactgtctt
    26341 gactccttga gctagatggt aaacgccatg cacttttcct tctccatcct gatagaagga
    26401 aactctcgca aagtaggcat ctgtctcttg aaccgcacgc acacgcgctt caaactgagc
    26461 caagccatct gcctctaaaa agcttttcaa gttctcacga ctaaagaaaa taggattaaa
    26521 aattccttgg caaatcgtaa aacgagctac agggtctgct agataggctt gaatacttgc
    26581 ttggaaataa gcttcaaaat caaaaccatc tagcccttca atatcagtcc ctgtataagc
    26641 aagcaaagca tctaaaaatg acttgataat ctgccagtct gtctttgtta gtaggtcagg
    26701 aagatcgaca cggtaagcct tttgaccatc agcataactg accttaaaaa gaaattgtga
    26761 ttgccccact atcgcacact caatatactc gagacgatta agaggctgac ggagatagac
    26821 tacatcatag ctatgtgact ccaaaccgtc tagcaaggcc aagatcgact tggcattcaa
    26881 aatctcttgt tctcctaaaa tgctctgttt atttggaata aaaaatgttt tcgccataac
    26941 tggactcctt tgaaatcgtt tacatacagt ataccttatt tttctgaaag atacaaaaac
    27001 aaactttaga tttttgagta caaagcatag aaaaacagcc cctgaggact gtttgatctt
    27061 atacagtagc tgcctgatcc aagctttcac cgatagcggc taggcgctca atcacttcag
    27121 cttgtgtcaa ttcatttttt gaaacatagc ggttacgtgg gtgaacacgg cactcgtgtg
    27181 agcatccacg aaggtacttg tcttcatttt cttctgatgt caagatacga cggttacaga
    27241 agggatttcc acagttgaca taacgttcac atggtgttcc atcaaaccag tctttcccta
    27301 cgatggttgg gttgacatgg ttgacatcaa cggcgatacg ctcgtcaaat acgtacattt
    27361 ttccatccca aagctcacct tgaacttctg ggtctttacc gtaagttgcg attcctccgt
    27421 gcaattggcc gacatctttg tagccttcac ggaccatcca gcctgagaat ttctcacagc
    27481 gaacgccacc tgtacagtaa accacgacac gcttgtccat gaatttttcc ttgttatcac
    27541 ggacccattg tggtaactca cggaagttgc gaatatctgg gcgaatagct ccacggaaat
    27601 gtcctaggtc gtactcataa tcgttacgtg tgtcaaggac aacggtatct ttatcaagaa
    27661 gcgcttcttt gaactctttt ggagacaagt aagcacctgt tgtttcaagt gggttgatgt
    27721 cattgtcaaa gtcgttgtct tccaaaccaa ggtggacaat ttctttcttg tagcgaacaa
    27781 acatcttctt gaaggcttgt tcattttctt cgtcaatctt gaaccagagt tcttccattc
    27841 ctggaaggct gtgaacgtag tccatgtatt tttgagttgt ttcatagtca cctgaaactg
    27901 ttccgttaat tccctcgtca gcgactagga tacggccttt aaggccgatt gatttacaga
    27961 aagccaagtg gtctgcagca aattgctctg cattttcaat tggagtataa aggtagtaaa
    28021 gtaagacacg aatatctttt gccataagat ttgttctctt ttctattctt aaattttcta
    28081 aattttttat ttatctacac tagtatacct gcttgagaaa acgaatgcaa tttatttgac
    28141 tggaaattgt agagggttct cgaaatttcc tgaatggtta aaataaggac aagagaaaac
    28201 atggatatct atatccttgt gccaaaaaaa ccactgccct ccccagacca acctgaggaa
    28261 agcagtgatt cttattttag gagttaggaa tgaatacacg aaatcaattt agctgattat
    28321 tttttgtttt tcaagaattc atcgtattgt ttttgcattt cgttcaatac tttttcgtag
    28381 gcaccttcag atttcaattt ttccatcaat tctggaatcg ctttatctgg gtctacagta
    28441 ccagtgttga tagctgtatc aaattgttgc attgtgttag caatagctga gatttcagat
    28501 ttcacattgt cagtattgaa gataaatcca agcgctggag attctttagc ttctgccaat
    28561 tctttcttag aattttcgat ttgttggtct gtaacgtttt cgttgatgta aaggatccag
    28621 ttgttaccag tgttccatcc acccatgtga gtgtttcctt tgtagccatc aagaacgcga
    28681 acacggtttt ctttaccttc aattttttcc cagttcttgc cttctggacc gtaaacaaga
    28741 ccgttcaaga gttctggatt cgtattcaag aggttcaaga tttccattga tttttctttg
    28801 ttcttagagt tgtttgagat gacaaagtta gcaacttgtg ttgtttggtt tttcttgatg
    28861 aagttagtaa ttggtttgat ttggatatct ttgttggcaa cacgtgaaag caagctgtta
    28921 ccgtagtcag ctggtcctac tgtttcttca cgaacgaacc aagtatcttg ttgaaggtca
    28981 aaggaagtat cgcttgttgc gacatctttt ggaatgtagc cagcttcata gaatttgtga
    29041 agagtcttca agtgttcttt gaaacgaggc acttcgtaac ggtttacaac tttagtagta
    29101 tcgccttcaa ggtcaataac gaatggaagc ccgtttgcta ctgggtagtc aaagttatca
    29161 gatgggatga aaactttacc aatagcaaat ggtactacgt ctggagcttt ttctttaatt
    29221 tgtttcaaga ctggctcaag agtttcgtaa gaagtaacac ctgaaatatc gataccatat
    29281 ttggcaagga gagttccgtt gaaggcaaag ttttgagatg atgcaacgtt ggctgcaact
    29341 ggaacagcgt aaattttacc gtttacagta ttacccttga tgtaagctgg gtcaagtgcc
    29401 ttgtaaaggt ctttaccttc ttttttgtac aattctgtca agtcagcata agcacctttt
    29461 tgagcattta caatatagtt atctgcaaag gcgatatcat agttttcacc agatgatgtg
    29521 ataactgaca ttttcttacc atagtcaccc cagccaaggt attggatatc caatttagca
    29581 ccaacttttt cttcgatgat tttgttggca tttgctaaca attcatccaa gttatctggt
    29641 ttgtcaccga tttggtacat tttgataaca ggtttgtcac ctgaatcagc agcttttttg
    29701 ctgttacctg tcaagttgcc acaagcagca agacctgcag ccagagcgac tacactagca
    29761 gatgcaaaag catatttttt ccagtttttc atgataaaaa ctcctttttt tatttttaaa
    29821 cttataaaca atgtaatgat cttatactca atgaaaatca aagagcaaac tagaaaacta
    29881 gccgcaggct gctcaaagca ctgttttgag gttgtagata agactgacga agtcagttac
    29941 atatatctac ggcaaggcga cgttgacgcg gtttgaattt gattttcgaa gagtattaac
    30001 ttcacacaag ggaagttggg aactgagaaa tgttcttttt caataagcac tattctttca
    30061 caccaccgat agtcaaacct tttacaaagt agcgttggaa gaatggatat aaaatcgcga
    30121 ttggaagggt tgcaaccaca accatggcca tacgacctgt ttctttcggt agagcaactc
    30181 ccagttgacc agtcaagccg accgctttgg caatgtagtc catattttgt tggatttgca
    30241 tgagcaaata ttgcaatgga tacaagttat cactcttgat gtaaagaagg gcgttgaacc
    30301 agtcattcca gaaaccaaga gctgtcaaaa gcgtgatggt tgcgatacct ggtagtgaca
    30361 atggcaaaca gatttggaag aaaatccggg cctcactggc accatcgata cgagccgatt
    30421 cgagaatggc ttctggaatg gtcttcttga agaaggaacg catcaagatg atattgaatg
    30481 gtgagagaag cattggaaca atcaaggccc aaacagtgtc cccaagctga agtacacggg
    30541 tcaccatgat ataacctggt accaaaccag cgttgaacaa catactgaga aggacgaaga
    30601 tggtaaaaaa tctgcgatac ttaaaggttg tccgtgaaat agcgtaggca taggttgttg
    30661 tgataaagac atttgtcaat gtcccaacta cggttacaaa gacagagatg aagagggctt
    30721 gtaggatttt atccttaaac tgtgccaaaa actcaaaacc gtctaagcca aattgggatg
    30781 ggaagaagct atagccgtat tggaggaggc ttttctcgtc tgtcactgaa ataatgataa
    30841 cgaatacaaa aggtaggata caagagaggg caatcaaacc cgaaatgata ctgaagaaga
    30901 tatctgcttt cttactgaag gagtgaatgc cgacattatc aattttttct tttttaattt
    30961 tcttttttgc catattctcc tcctttctag aacaaagctg agtttggatc gactcgtctt
    31021 gcaagcaagt ttgataggat aaccagaatc aaaccaacaa cggattggta aagaccggct
    31081 gctgcagcca taccgatatc tgctgtctga gtcaaaccat taaagacata tacgtccaaa
    31141 acgttggtta cattgtaaag ctgaccagca ttgtgtggga tttgatagaa gagaccgaag
    31201 tctgcgcgga agatatttcc gactgcaagg atggtcaata cagttacaag cggagtcaac
    31261 tgaggaatgg ttacgttgcg aatacgttgc cacttgctag ctccgtccac tgtcgctgct
    31321 tcgtagtagg ttggatcaat tcccatgatc gtcgcatagt acatgacact gctatatcca
    31381 aatcctttcc aaatacctag gaaaagtagg agatagggcc agatgcccag gtcagcgtag
    31441 aaattgactt ctttgagacc aagactttcc aatagatgat tgaacacccc tttatcaata
    31501 tttaggaagg catctgtaaa gaaactgatg ataacccaag acaagaagta agggaacaac
    31561 atagaagttt gaaaaatctt caccattctc ttagaacgga gctcgctgag gataatggcg
    31621 atccctacag atacaactaa acctagaaag ataaagccaa gattgtagag gacagtattt
    31681 cgtgtgataa taaaggcgtc tcttgaacta aataagaatc taaaattatc gagtccgacc
    31741 catttactat ttatgatact atctatgaaa ccattactgg tcatgtggta gtctttgaag
    31801 gcaaccacgt tcccaaatac tggaatgtaa aagaatagaa tcaaccagag tgcccctggc
    31861 aaaaccatca agagaaagat ccagttgtct ctcaatgttt ttgaaaactt tttcataatt
    31921 tcctcccttt ttattttgat atccatctaa aaattctttt ttagactttt gataacgatt
    31981 acattattag tatactccta tttgcaggtt aggttaaact cctaattata gaaaaaactc
    32041 cacaaattat gtagcagatt taaaacttta tcaccactat caaacaaatg tcctaaatca
    32101 attgtttatt ttatctctat tagcccagtg atggcgtcac tctgttataa gcatccaaca
    32161 acggggtata ctgaaaaatc tccagactag ggaactcagc gatagttcct aatctggaga
    32221 tttttaatat gttattaggc gtttgctttc aacttagcaa taacctcttt aagattatca
    32281 atcaactctg ctgcagtatg ctcagagcct ttttcatctg ccaagaacaa aactgctttt
    32341 tgaagttctt tttgagagtt ttcaaggaca tccttatcta ctgtttcaag gtttgagtct
    32401 ttaagaagtt tacttaattc cttggctaat ttcttgagtt tgatttgcag actcatcttc
    32461 tcctgctgtt tctttgcccg ctgtttgtcc tccatcctta gttgctgact ggctttcctt
    32521 aatggactct agggaagcaa tggcatcttt gactgtttgc aagatatcac gtaaaccttg
    32581 ctctgtcaaa ctatcatctg taagagcttt cttagcctct gccaaaacca gacgtgctga
    32641 atctgtggta ggattcgata cacctgtcaa tgatctcaaa agattttcta aggtttgagt
    32701 ctgcttacta atactagact aaaatcaaaa agcattacat aacagtgata tgaaatcaac
    32761 taaagaagaa atccaaacca tcaaaacact tttaaaagac tctcgtacag ctaaatatca
    32821 taaacgcctt caaatcgttc tatagtaaaa tgaaacaaga acaggacaaa tcgatcagga
    32881 cagtcaa
//
LOCUS       DAVKBK010000021        29209 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVKBK010000021 DAVKBK010000000
VERSION     DAVKBK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.021"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            195..692
                     /locus_tag="VWX69_001054"
     CDS             195..692
                     /locus_tag="VWX69_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU9192414.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            692..2347
                     /gene="dnaX"
                     /locus_tag="VWX69_001055"
     CDS             692..2347
                     /gene="dnaX"
                     /locus_tag="VWX69_001055"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU9192415.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2375..2569
                     /locus_tag="VWX69_001056"
     CDS             2375..2569
                     /locus_tag="VWX69_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU9192416.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2719..3489
                     /gene="sufC"
                     /locus_tag="VWX69_001057"
     CDS             2719..3489
                     /gene="sufC"
                     /locus_tag="VWX69_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU9192417.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEGDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3517..4779
                     /gene="sufD"
                     /locus_tag="VWX69_001058"
     CDS             3517..4779
                     /gene="sufD"
                     /locus_tag="VWX69_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU9192418.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4790..6016
                     /locus_tag="VWX69_001059"
     CDS             4790..6016
                     /locus_tag="VWX69_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9192419.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6003..6443
                     /locus_tag="VWX69_001060"
     CDS             6003..6443
                     /locus_tag="VWX69_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU9192420.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6497..7909
                     /gene="sufB"
                     /locus_tag="VWX69_001061"
     CDS             6497..7909
                     /gene="sufB"
                     /locus_tag="VWX69_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU9192421.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8108..9349)
                     /locus_tag="VWX69_001062"
     CDS             complement(8108..9349)
                     /locus_tag="VWX69_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU9192422.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9452..10561
                     /locus_tag="VWX69_001063"
     CDS             9452..10561
                     /locus_tag="VWX69_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9192423.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11207..11554
                     /gene="ssrA"
                     /locus_tag="VWX69_001064"
     tmRNA           11207..11554
                     /gene="ssrA"
                     /locus_tag="VWX69_001064"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11737..11824)
                     /locus_tag="VWX69_001065"
     tRNA            complement(11737..11824)
                     /locus_tag="VWX69_001065"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11788..11790),aa:Ser,seq:gga)
     gene            11987..12727
                     /locus_tag="VWX69_001066"
     CDS             11987..12727
                     /locus_tag="VWX69_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9192424.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12724..13635
                     /gene="pfkB"
                     /locus_tag="VWX69_001067"
     CDS             12724..13635
                     /gene="pfkB"
                     /locus_tag="VWX69_001067"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU9192425.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13632..15584
                     /locus_tag="VWX69_001068"
     CDS             13632..15584
                     /locus_tag="VWX69_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9192426.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHSYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQVP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15748..17973
                     /locus_tag="VWX69_001069"
     CDS             15748..17973
                     /locus_tag="VWX69_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU9192427.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(18124..18552)
                     /locus_tag="VWX69_001070"
     CDS             complement(18124..18552)
                     /locus_tag="VWX69_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192428.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            18690..19832
                     /locus_tag="VWX69_001071"
     CDS             18690..19832
                     /locus_tag="VWX69_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9192429.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19841..21055
                     /gene="thiI"
                     /locus_tag="VWX69_001072"
     CDS             19841..21055
                     /gene="thiI"
                     /locus_tag="VWX69_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU9192430.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21190..22014
                     /locus_tag="VWX69_001073"
     CDS             21190..22014
                     /locus_tag="VWX69_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9192431.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            22027..23193
                     /locus_tag="VWX69_001074"
     CDS             22027..23193
                     /locus_tag="VWX69_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9192432.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(23684..25354)
                     /locus_tag="VWX69_001075"
     CDS             complement(23684..25354)
                     /locus_tag="VWX69_001075"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU9192433.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIYVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            25584..26273
                     /gene="coaB"
                     /locus_tag="VWX69_001076"
     CDS             25584..26273
                     /gene="coaB"
                     /locus_tag="VWX69_001076"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU9192434.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            26285..26836
                     /gene="coaC"
                     /locus_tag="VWX69_001077"
     CDS             26285..26836
                     /gene="coaC"
                     /locus_tag="VWX69_001077"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU9192435.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            26820..27383
                     /locus_tag="VWX69_001078"
     CDS             26820..27383
                     /locus_tag="VWX69_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9192436.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            27661..28188
                     /locus_tag="VWX69_001079"
     CDS             27661..28188
                     /locus_tag="VWX69_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9192437.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            28200..28715
                     /locus_tag="VWX69_001080"
     CDS             28200..28715
                     /locus_tag="VWX69_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU9192438.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(28712..29179)
                     /locus_tag="VWX69_001081"
     CDS             complement(28712..29179)
                     /locus_tag="VWX69_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9192439.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGSLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
BASE COUNT         8588 a         5657 c         6227 g         8737 t
ORIGIN      
        1 atatgattct ttctaatgag ttgttttgtt gcttttcatt ataggtcata tgggactttt
       61 tttctacaca aaataggctc cataatatcc ataggggatt tacccactac aaatattata
      121 gagcccaaaa tcctttgttt actaaacaag ggatttttct tttgtctctg ctcctttttt
      181 gatataatag ttctatgtta aaatcagaaa aacaatcacg ttatcaaatg ttaaatgaag
      241 aattgtcctt cctattggaa ggcgaaacca atgttttggc taatctttcc aacgccagtg
      301 ctctcataaa atcacgtttt cctaataccg tatttgcagg cttttatttg ttcgatggaa
      361 aggaattggt tttaggcccc ttccaaggag gtgtttcctg catccgtatt gcactaggca
      421 agggtgtttg tggtgaggca gctcactttc aggaaactgt tattgttgga gatgtgacga
      481 cctatctcaa ctatatttct tgtgatagtc tagctaaaag tgaaattgtg gtgccgatga
      541 tgaagaatgg tcagttactt ggagttctgg atctggattc ttcagagatt gaggattacg
      601 atgctatgga tcgagattat ttggaacaat ttgtcgctat tttgcttgaa aagacaacat
      661 gggactttac gatgtttgag gaaaaatctt aatgtatcaa gcactttatc gaaaatatag
      721 aagtcaaaac ttctcccagt tagttggtca agaagttgtg gctaagactc ttaaacaagc
      781 ggtggagcaa gagaaaataa gtcacgctta tcttttttct ggtcctcgtg gaacgggaaa
      841 aaccagtgtt gctaaaatct ttgccaaggc tatgaactgt cccaatcaag tgggtggcga
      901 accttgcaat aactgctata tttgtcaagc agtgacggac ggtagtttag aagatgtcat
      961 tgaaatggat gcagcttcta ataatggggt agatgaaatt cgcgaaattc gtgataaatc
     1021 tacctatgcg cctagccttg ctcgttataa ggtttatatc atagatgagg ttcacatgct
     1081 gtctacaggg gcttttaatg ccctcctaaa gacgctggaa gaaccaacac agaatgtagt
     1141 ctttattttg gccactactg aattgcacaa gattcctgct actattctat cccgtgtgca
     1201 acgttttgag tttaaatcaa ttaagacaca ggatattaag gaacatattc actatatctt
     1261 agaaaaagaa aatatcagtt ctgaaccaga ggctgtggaa atcattgcca ggcgggcgga
     1321 aggtggaatg cgggacgcct tgtctatttt ggatcaagcc ctgagtttga cacagggaaa
     1381 tgagctgacg actgctatct ctgaagaaat tactggcacc attagcctat cagccttgga
     1441 tgattatgtg gcggccttgt ctcaacagga tgttcccaaa gctttgtctt gcttgaatct
     1501 tctttttgac aatggtaaga gcatgactcg ttttgtgacc gatcttttgc actatttaag
     1561 agacttgtta attgttcaaa cagggggaga aaatactcat catagttcag tctttgtaga
     1621 aaatttggca cttcctcaaa aaaatctgtt tgaaatgatt cgcttagcaa cagtgagttt
     1681 agcagatatt aagtctagtt tgcagcccaa gatttatgct gaaatgatga ccgtccgttt
     1741 ggcggaaatc aagcccgaac cagctctatc aggagcggtt gaaaatgaaa ttgctacgct
     1801 gagacaggaa gttgcccgtc tcaaacaaga gctttctaat gtaggtgcgg ttcctaaaca
     1861 agttgcacca gctcctagtc gaccagctac gggcaaaaca gtctatcgtg tcgatcgcaa
     1921 taaagtgcaa tctatcttac aagaggccgt cgaaaatcct gatttagcac gtcaaaatct
     1981 aattcgtttg cagaatgcct ggggagaggt aattgaaagt ctaggtgggc cggacaaggc
     2041 tctgctagtt ggttctcaac cggttgctgc caatgaacac catgctattc ttgcttttga
     2101 gtctaacttc aatgctggtc aaactatgaa acgagacaat ctcaatacca tgtttggtaa
     2161 tatcctcagt caggcggcag gtttttcacc tgagatttta gctatttcca tggaggaatg
     2221 gaaagaagtt cgcgcagcct tttcagccaa agccaaatct tctcaaactg aaaaagaagt
     2281 agaagaaagc ctgattccag aaggatttga atttttggct gataaagtga aggtagagga
     2341 agactaaaga aagatttcat gatacaataa gtttatgaat aaacaacaat ttattattat
     2401 ggcgctgttt acagctgctg agacctattt tttcaatgaa gcctggatga ctggccgcta
     2461 tattatggca gccttttggg caattttact ctttagaaat ttccgagtca gttatgtgat
     2521 gggcaaaatc gttgatgtca tcgatcagca ttttaatagg aaagactagc cctcagcttc
     2581 cagacaaaat caaagccttt taggcttttt tttgttatac tagaaaagta tatttataga
     2641 atttttgctc tatttctggg gaaatcagac gtttttctag taagtactgt aaaagttttg
     2701 aaaaagaaag gaactatcat gtcagtatta gagattaaag atcttcacgt tgagattgaa
     2761 ggaaaagaaa ttttaaaagg ggttaacctg accctgaaaa caggagaaat tgccgctatc
     2821 atgggaccaa atggtacagg taaatcgact ctttctgccg ctatcatggg aaatccaaac
     2881 tatgaagtaa ctaaaggtga agttttgttt gatggcgtaa acatccttga gttggaagtg
     2941 gatgagcgtg cgcgtatggg acttttcctt gctatgcaat acccatcaga aatccctgga
     3001 attaccaatg ctgagtttct tcgtgccgct atgaatgcgg gtaaagaagg tgatgagaag
     3061 atttcagttc gtgagtttat tactaagcta gatgaaaaaa tggaattgct caacatgaaa
     3121 gaagaaatgg cagagcgtta cctcaacgaa ggcttctctg gtggtgagaa aaaacgcaat
     3181 gaaattcttc aacttttgat gttggagcca acatttgctc ttttggacga gattgactca
     3241 ggtcttgata ttgacgctct taaagttgtg tctaaaggtg tcaatgccat gcgtggtgaa
     3301 ggttttggtg ctatgatcat cactcactac caacgtcttt tgaactatat cacacctgat
     3361 gtggtacacg tgatgatgga aggtcgtgtt gtcctttctg gtggtccaga attggctgcg
     3421 cgtttggaac gtgaaggata cgcaaaatta gctgaagaac ttggctacga ctacaaggaa
     3481 gaattgtaat ttcctcgtat cttttaggag aagtaaatga ctagagaaaa tattaaactt
     3541 ttttcagaaa tgcacgctga accaagctgg ttggctgatc tccgtcaaaa agcttttgac
     3601 aagattgaga ctttggaatt accagttatt gagcgtgtca aattccaccg ttggaatctg
     3661 ggtgatggaa cgattacaga aaatgagcca tcagcaaatg ttccagattt cacagcttta
     3721 gatcatcact tgaagttggt gcaagtagga actcaaactg ttttcgaaca aactccagtt
     3781 gagttagctg aacagggtgt tgtcttcaca gactttcact cagctttaga agaaattcca
     3841 gagctgatcg aagaattctt catgtcatct gttaagtatg atgatgacaa gttggcggct
     3901 taccacacag cttactttaa cagtggtgct gtactctata ttccagataa cgtagaaatc
     3961 acagagccaa ttgaaggaat tttctaccaa gatagcgata gcaatgtgcc gtttaacaag
     4021 catattatga ttatcgctgg taaaaattct aagattagtt atctggagcg tttagagtca
     4081 cgcggtgaag gaagtgacaa agcaactgcc aatatcacag tggaagtgat tgcacgttct
     4141 ggtgcgcaag tcaagtttgc tgctattgac cgtctaggtg aaaacgtcac tgcctacatt
     4201 agccgtcgtg gtaaattagg caacgatgca agtattgact gggctatcgg tgtcatgaac
     4261 gaaggaaatg tcgttgctga ttttgatagt gacttgattg gtaatggtag ccatgctgac
     4321 ctcaaggttg tagctctttc aagtggtcgt caggtacaag ggattgatac tcgtgtaact
     4381 aactatggct gcaactctat cggaaatatc ctacaacatg gggttatcct tgaaaaagca
     4441 actttgactt tcaatggtat cggccacatc atcaagggtg ctaagggagc agatgcccaa
     4501 caagagagcc gtgttctcat gctttcagac caagcgcgtt cagatgctaa cccaattctt
     4561 ttgattgatg aaaatgacgt cactgcagga catgcagcct ctattggtca ggtagatcca
     4621 gaagatatgt actacctcat gagtcgtgga ttggataagg caactgcaga gcgtttggtt
     4681 gttcgtggtt tccttggatc tgttatcgtg gagattccag tcaaggaagt tcgtgatgaa
     4741 atgattgcaa ctatcgaaga gaaattgtca aaacgctaag gggaagccta tgttagatgt
     4801 agaagcgatt cgcaaggatt ttccaatttt agatcagatt gtcaatgatg aacctctggt
     4861 ctatctggac aatgctgcga cgacacaaaa accactagta gttctgaaag ctattaacag
     4921 ttactatgag caggacaatg ccaatgttca ccgtggtgtc cataccttag cggaacgagc
     4981 gacagcttct tatgaagctg ctcgtgaaac cattcgtaag tttattaatg caggctctac
     5041 aaaggaagtt ctctttacca gaggaacgac aaccagcctt aactgggtgg cacgctttgc
     5101 tgaggaaatt ctcactgagg gagaccaggt cttgatttca gtaatggaac accattctaa
     5161 tatcattcca tggcaggaag cttgtcgaaa gactggagca gagcttgtct atgtctatct
     5221 taaagacggt gccttggata tggaggattt gcgagctaaa ttgactgata aggttaaatt
     5281 tgtttcccta gctcatgcct ccaatgttct tggtgtggtc aatccgatca aggaaatcac
     5341 tcaattagcc caccaagttg gggcaatcat ggtagtggat ggtgctcaat ctacacctca
     5401 tatgaagatt gatgtccagg acttggatct ggactttttc gccttttcgg gtcacaagat
     5461 ggctggtccg actggtatcg gtgtccttta cggcaaagaa aagtatcttg agcaaatgtc
     5521 tccagtagaa tttggcggcg agatgattga ttttgtctac gagcaatctg ctagttggaa
     5581 ggaattgcct tggaaatttg aggctggaac gccaaatatg gcaggagcta ttggacttgc
     5641 gactgcagtt gattatctgg aaaagattgg tatggatgcc gttgaagctc atgaacagga
     5701 attgattgcg tacgtctatc caaaactgca ggcaattgag ggattgacca tttacggttc
     5761 tcaggatttg gctcaacgtt cgggtgttat tgcctttaac ctaggtgatc tccatcctca
     5821 cgatcttgcg acagctctgg attatgaagg agtggctgtt cgtgctggtc accattgtgc
     5881 gcaacccttg cttcagtatt tggaagtccc agcaacagct cgtgcaagtt tttatatcta
     5941 taataccaag gcagattgcg acaaactagt cgatgcccta caaaagacaa aggagttttt
     6001 caatggcact ttctaaacta gatagccttt atatggcagt ggtagcagac cattcgaaaa
     6061 atccacatca ccaagggaag ttagaagacg ctgagcaaat cagtctcaac aatccgactt
     6121 gtggagatgt catcaatctc tctgtcaagt ttgatgcaga ggaccgtttg gaagatattg
     6181 cttttctaaa ttcaggatgc acgatttcaa ctgcttctgc tagtatgatg acagatgccg
     6241 ttttaggaaa aaccaaacaa gaaattttag aactggcgac tattttttct gaaatggttc
     6301 aagggcaaaa agatgagcgt caagaccaac ttggagacgc ggcattcttg tcaggtgttg
     6361 ccaaattccc tcaaagaatc aagtgtgcaa ccctagcttg gaatgccctt aagaaaacaa
     6421 ttgaaaatca agaaaaacag taagacaagt ttcttttgtc ttatgaatta ttagaaatga
     6481 agaaagaaag gatattatgg ctgaagaaag agtagaacca aaaccaattg accttggtga
     6541 atataaattt ggtttccatg acgatgtaga gcctgtctta tcgacaggaa aaggactcaa
     6601 cgaaggtgtt attcgtgaat tatctgctgc taagggtgag cctgagtgga tgttggagtt
     6661 ccgtttgaag tcttatgaaa ccttcaaaaa aatgcccatg caaacttggg gagcagactt
     6721 gtcagagatt gactttgatg acttaatcta ctaccaaaaa ccatctgaca aaccagcccg
     6781 ttcttgggat gatgtacctg aaaagattaa agaaaccttt gaacgtatcg ggattccaga
     6841 agctgaacgt gcttatttag caggggcttc tgcccagtac gagtcagaag tggtttacca
     6901 caacatgaag gaagagttcc aaaaattagg tattatcttt acagatacag attccgcact
     6961 caaggaatac ccagacttat ttaatcaata ctttgcgaag ttggtaccgc cgacagataa
     7021 caagttggca gccctcaact cagcagtatg gtcgggtgga acttttatct acgtgccaaa
     7081 aggtgtcaag gtagatattc cacttcaaac ttatttccgt atcaataacg aaaatatagg
     7141 tcagttcgaa cgtaccttga ttatcgttga tgagggagca agcgtccact acgtagaagg
     7201 atgtacagca ccaacatatt caagcaatag cttacacgct gccattgtag aaatttttgc
     7261 tttggacgga gcttatatgc gttatacaac tatccaaaac tggtctgata acgtctataa
     7321 cttggtaaca aagcgtgcta aggctcaaaa ggatgccact gttgagtgga ttgatggaaa
     7381 cttgggtgcc aaaacgacta tgaaatatcc atctgtttac cttgatggag aaggagcgcg
     7441 tggtaccatg ctctctatcg cctttgctaa tgcagggcaa caccaagaca cgggtgctaa
     7501 gatgattcac aatgctccac ataccagctc gtctattgtg tctaaatcca tcgctaaagg
     7561 tggaggaaag gttgactacc gtggacaagt cacctttaac aagaactcta agaaatctgt
     7621 ttcccacatt gaatgtgata ccattatcat ggatgacttg tcagcatcag atactattcc
     7681 atttaatgaa attcacaact cgcaagtggc tttggaacac gaagccaaag tatctaagat
     7741 ttcagaagag caattgtatt atctcatgag ccgtggattg tcagaatctg aggcaactga
     7801 aatgattgtc atgggatttg tagaaccctt tacaaaagaa cttccaatgg aatacgcagt
     7861 tgagctgaac cgcttgatta gctatgaaat ggagggatca gttggataaa atttgatttt
     7921 atactcttcg aaaatctctt caaaccacgt cagcatcgcc ttaccgtatg tatggttact
     7981 gacttcgtca gtttcatcta caacctcaaa acagtgtttt gagcaacctg cggctagctt
     8041 cctagtttgt tctttgattt tgaagatgaa cttgtatcaa aaaatcgcgg tttaaaatcg
     8101 cgatttttta taatttctcg ttaacaaagc ggacaaactg attccaccaa acttttaaga
     8161 agaaggcttt ttcaattttc ttgtctgcta ccatttcgaa actagggcgc tctgtggtga
     8221 tgtaaccttg accaatcaag tccttgtctt cataagtcaa atggccaacc actgttccag
     8281 cttcaagtgg tgctgggatt gctttggaat caggtgtgaa ttgaacagat tgggaagatt
     8341 gattcccaac acgttctatt agatagatat cctctggagc cactgcagtt actgtatctt
     8401 cttttccatc ttgtacaggg gttttgctat cttgataggc atcgccttgt tgaacgattt
     8461 tgcgaagtgt aaatgtagaa gaaatataat ccattaggga agatgtagct gtaaatcgag
     8521 cgtaaggatt attgtcttga tgatctgcat ttaaaacaac tgtgatgact ctcatgcctt
     8581 tttcgacagt agtaccaaca aaagactctc cagccttatc tgttgttcct gtttttagcc
     8641 catcaaaacc accacggtaa gcaggcatac cttctaacat gtagttggtt gaagtgattg
     8701 tcatcccagc aaaagtagaa gaaggttttt tggtgatttc taagacttgt gggtattttt
     8761 tgatgaggtt gcgagcaacg atagcgacat cataagcact aagcttattt tcctcatctt
     8821 ttttagaacc tgggtaaatg ttatccccta gagtttcatt gttaagacct gtcgtattga
     8881 caacagtggc atcctgaatt ccccattcca agagttttgc ccgcatcata tcgacgaaat
     8941 ctttttctga gccagcaatt ttctcagcta gggcaatagc ggcgctgttg gcactagata
     9001 ccagagttgc ttcaagcaac tcttcgacag tataattacg ggcctccata ggaatattac
     9061 tggcttcaga atttgtcgtc aattgataag gataatcaga aatatctaca ggagtggaga
     9121 gggtaatact tccgttttcc aaagcttcat agaccagata aacagtaatc aattttgtta
     9181 tggaagcaat ttcgacaggt tgcgttgcat ccttctcata gagaatttta ccagtatttg
     9241 cctcaacagc aatcgcatgt ttagcggcaa tggtaaaatc ttgagcaaca gcagtagaag
     9301 caccccctaa aagagagaca gttaacaaag ttaaaaatat ttttttcata gtagtcttat
     9361 tctatcataa agaaaaaaaa tattcttgct ttaataattc atctgttaag ctttttgaaa
     9421 atatggtaaa ataaagtgag ggaggtaact catgtttcgt agaaataaat tatttttttg
     9481 gaccacagaa attttactct taaccatcat cttttaccta tggagacaga tgggatcttt
     9541 gattaaccct tttgttagcg tgcttaatac aattatgatt ccatttttat tagggggctt
     9601 tctttattat ttgacaaacc ctattgttac tttcttaaat aaagtctgta aactcaatcg
     9661 tttgcttggt attttaatta ccttgtgtac tttggtctgg ggaatggtca taggtgttgt
     9721 ctatctctta cctattttga ttaatcagtt atctagtttg attatatcta gtcaaactat
     9781 ttatagtcga gtacaagact taatcataga cttatctaat tatcctgcgc tccagaattt
     9841 ggatgtagaa gctacaattc agcagttaaa cttatcctat gttgatattc ttcaaaatat
     9901 cctaaatagc gtatcaaata gtgtggggag cgtcttgtca gctcttatca gtactgtttt
     9961 gattttgatt atgactccag tttttttggt ttatttctta ttagatggac ataaattctt
    10021 gcccatgctt gaaagaacga ttctaaagag ggatcgcttg catattgcag gcttattaaa
    10081 gaatttaaat gcgacgattg ctcgctatat tagtggagtt tcgattgacg caatcattat
    10141 aggttgtttg gcttatattg gctatagtat tattggttta aaatatgctt tagtttttgc
    10201 cattttttct ggtgtagcca atttaattcc ttatgtgggg ccaagtattg gtttgattcc
    10261 tatgatcatc gcaaatatat tcactgatcc ccatagactg ctgattgcag tgatttatat
    10321 gcttgttgtt cagcaggtag atggcaatat cttatatcct cgaattgtag gaagtgttat
    10381 gaaggttcat ccaatcacga ttttagtttt acttttgttg tcaagcaata tctatggtgt
    10441 agttggaatg attgtcgcag tgccaaccta ttctatcttg aaagaaattt ctaagttctt
    10501 atcccgtttg tatgaaaatc ataaaataat gaaagaacga gaaagagaat tagctaagta
    10561 aaagtcagga gaaccctgat ttttctttac tggaagtggc ctttagatta gaagactgaa
    10621 aataagttaa agtcttaaac taattttcac agctaagaat agtagaagtt aatctgataa
    10681 aaatcgaaaa aaccagtgga attccgtgtc agggtaagtt ccactggttt tcatagtcta
    10741 ttaaagttcg aatgaaacct atttataata tattgaaact agaatagtac acctctaatt
    10801 ctaaaacatt gttagaaatc gatttgactg tcctgatcta ttcgtactat tcttatttca
    10861 ttttactata ttttggtgca ataagtgaaa agtagtccga ataatataag gattgatttt
    10921 atagttttta aactcaaatg aattaaaata aagagagtac gaaaattctc atctgaaagt
    10981 attttagaat aattctcttc gtgaatttct tcaaaacaga tagcttcatc ttaggtatgt
    11041 gttaattgga tttcgtaagc tctatttaca atcgtaaagt tatgcactga gaaagttgta
    11101 gttagtcttc cagtttgcta aatttctcga atagtatctt ttttaggtat gtgatttctt
    11161 tttgcatttt tgagttagat aaggtataat ggttttattg tcttttgggg tcgttacgga
    11221 ttcgacaggc attatgaggc atattttgcg actcgtgtgg cgacgtaaac gctcagttaa
    11281 atataactgc aaaaaataac acttcttacg ctctagctgc ctaaaaacca gcaggcgtga
    11341 cccgatttgg attgctcgtg ttcaatgaca ggtcttatta ttagcgagat acgattaagc
    11401 cttgtctagc ggcttgataa gagattgata gactcgcagt ttctagactt gagttatgtg
    11461 tcgaggggtt gttaaaataa tacataacct atggttgtag acaaatatgt tggcaggtgt
    11521 ttggacgtgg gttcgactcc caccggctcc attattcctt tgcattcttt tgcattcctt
    11581 ggtaaaacgt tgttaaatca acgtttttta tttttatctt tggtattcct ttgcattctt
    11641 ttgctaaaaa gggagtcaca aacagaccct attttaaaaa aaggatagaa aaaaggatac
    11701 aacatttgtc gcatcctaga aataatcttt tttcgacgga agacatggga ttcgaaccca
    11761 cgcacgctat tacacgccta ccgcgtttcc aacacggcct cttaagcctc ttgagtaatc
    11821 ttccaatact tactcaaata gtctaccata aaggctctta tcttgcaata aaaattctag
    11881 aaataagaaa aaatgataga ttttgaaaga aaatgataaa aaatgcttga cttcgaaaga
    11941 aagtatgata gaatgaatag tgtaaacgat aacaggaggt gattcagtgt taaaaacaga
    12001 acgtaaacaa ctaattttag aggagttaaa tcaacatcat gtagtttctc tagaaaaatt
    12061 agttagtttg ctagaaacgt cagaatcaac ggttcgaaga gacttggatg agttggaagc
    12121 ggaaaacaag cttcgtcgtg tgcatggtgg agcagaactc ccccactcct tacaggaaga
    12181 agaaaccatt caagaaaaat ctgtcaaaaa ccttcaagaa aagaagttgc tggctcagaa
    12241 agcagcctct ctcattaaag aaaaagatgt catctttatc gatgctggaa caacaactgc
    12301 ttttttgatt catgaattgg tcaataagaa tgttacagtt gtgaccaact ccattcacca
    12361 tgccgctcag ttggttgaaa agcagattcc aactgtcatg gttggaggaa acgtcaagac
    12421 ggcgacagat gctagtatcg ggggcgttgc tcttaaccag attaaccaat tgcactttga
    12481 ccgtgccttt atcggaatga atggtgttga cgatggctat tatacgactc ctgatatgga
    12541 ggaaggagct gtgaaaagag ctattttgga gaatgccaag cagacctacg tcttggtgga
    12601 ttcgtcaaaa attggacaaa cttgctttgc caaggtagca ccactcaaac gcgctatcgt
    12661 tatcactagt caagggcatg agctcttgca ggttattaag gagaaaacgg aggtaataga
    12721 agtatgattt atacagtcac actcaatcca tccattgact atatcgttcg tttggaccaa
    12781 gtcaaagttg gtagtgtaaa tcgtatggac agtgatgata agtttgctgg tgggaaagga
    12841 atcaatgtca gccgtgtctt gaaacgtttg aatataccaa atacagcgac gggatttatc
    12901 ggtggcttta ctggtaaatt tatcacagat actttagcag aggaagaaat cgagacacgt
    12961 tttgtccagg tggcagaaga tactcgtatc aatgttaaaa tcaaagcaga ccaagaaaca
    13021 gaaatcaacg gaacgggtcc aactgttgaa ccggttcagc tagaagaatt gaaagctatt
    13081 ttatctagtc tgacagcaga agatacagtt gtctttgcag gttcaagtgc taaaaatcta
    13141 ggcaatgtta tctataagga tttgatttcc ttgacgcgcc agactggtgc gcaagtggtc
    13201 tgtgactttg aaggacagac cttaattgat agtttggact accagcctct tcttgtaaaa
    13261 ccaaacaatc atgaacttgg agcgattttt ggggttaaac tcgaaagttt agatgaaatt
    13321 gagaaatacg ctcgtgagtt actggctaag ggtgctcaaa atgttattat ctctatggct
    13381 ggtgatggcg cccttcttgt cacatctgag ggagcttact tcgctaaacc aatcaaagga
    13441 acagtcaaaa attcagttgg agctggtgat tctatggttg ctggattcac aggtgaattt
    13501 gtcaaatcaa aagacgcagt agaagccttc aaatggggag tggcttgcgg aacggcaact
    13561 accttctcag atgacttggc aacggcggaa tttattaaag aaacatatgg aaaagttgag
    13621 gtagaaaaaa gatgaaaatt caagacctat tgagaaaaga tgtcatgttg ctagatttgc
    13681 aggcaactga aaaaacagct gtcatcgacg agatgattaa aaatttgaca gagcacagtt
    13741 atgtaacaga ttttgaaaca tttaaagaag gaattttggc gcgtgaagct ttgacttcta
    13801 ctggtttggg tgatggaatc gcaatgcctc acagcaaaaa cgctgctgtc aaagaagcga
    13861 cagttctatt tgctaagtca aataagggtg ttgactacga gagcttggat ggacaagcaa
    13921 ctgacctctt cttcatgatt gcagctccag aaggtgccaa tgatactcac ttggcagcct
    13981 tggcagaatt gtctcaatac ttgatgaaag acggttttgc agacaaactt cgtcaagcaa
    14041 catctgcaga ccaagttatc gaactttttg accaagcttc agaaaaaact gaggaacttg
    14101 ttcaagtacc tgctaatgac tctggtgact ttatcgtagc tgttacagct tgtacaacag
    14161 gtattgccca cacttacatg gcccaagaag cccttcaaaa agtagctgct gaaatggggg
    14221 ttggtatcaa ggtcgaaacc aacggtgcta gcggtgttgg aaatcaacta actgcagaag
    14281 atatccgtaa ggctaaagct attatcattg cagcagacaa ggccgttgaa atggatcgat
    14341 ttgatggaaa accattgatc aatcgtccag ttgctgacgg tatccgtaag acagaagagc
    14401 taattaactt ggctctttca ggagatactg aagtctaccg tgccgctaat ggtgcaaaag
    14461 ctgcaacagc ctctaacgaa aaacaaagcc ttggtggtgc cttctacaaa cacttgatga
    14521 gtggtgtatc tcaaatgtta ccattcgtta tcggtggtgg tatcatgatt gcccttgcct
    14581 tcttgattga cggtgctttg ggtgttccaa atgaaaacct tggcaatctt ggttcttacc
    14641 atgagttagc ttctatgttc atgaaaattg gtggagctgc ctttggtttg atgcttccag
    14701 tctttgcggg ttatgttgcc tactctattg ctgaaaaacc aggtttggta gcaggtttcg
    14761 tggctggtgc tattgccaaa gaaggttttg cctttggtaa aattccttat gccgcaggtg
    14821 gtgaagcaac ttcaactctt gcaggtgtct catctggttt cctaggtgcc cttgttggtg
    14881 gatttatcgc aggtgccttg gttcttgcca tcaagaaata cgttaaagtt cctcgttcac
    14941 tcgaaggtgc taaatcaatc cttctattgc cacttcttgg aacaatcttg acaggatttg
    15001 ttatgctagc tgtgaatatc ccaatggcag caatcaacac tgctatgaat gacttcctag
    15061 gcggtcttgg aggaggttca gctgtccttc ttggtatcgt ccttggtgga atgatggctg
    15121 ttgacatggg tggaccagtt aataaagcag cttatgtctt tggtacaggt acgcttgcag
    15181 caactgtttc ttcaggtggt tctgtagcca tggcagcagt tatggctgga ggaatggtgc
    15241 caccacttgc aatctttgtc gcaactcttc ttttcaaaga taaatttact aaggaagaac
    15301 gtaactctgg tttgacaaac atcatcatgg gcttgtcatt tatcactgag ggagcgattc
    15361 catttggtgc cgctgaccca gctcgtgcga ttccaagctt catccttggt tcagcagtag
    15421 caggtggact cgttggtctt actggtatta aactcatggc gccacacgga ggaatcttcg
    15481 ttatcgccct tacttcaaat gctctccttt acctcgtttc tgtcttggta ggagcaatcg
    15541 taagtggtgt ggtttatggt tacctacgca aaccacaagc ataaaaaata gaaaaatgaa
    15601 aagattggac cgtttggtgc agtctttttc tctttccgaa atgcctgtga aatatggtat
    15661 aatagaagaa tggcaaacaa gaatacaagt acaacaagac ggagaccgtc taaagcagaa
    15721 ctggaaagaa aagaagcgat tcaacgaatg ttgatttcgt taggaattgc gattttattg
    15781 attttcgcag ccttcaaatt aggggctgca ggtataaccc tttataattt aattcgcttg
    15841 ctagtgggta gcctagctta tctggcgata ttcggcctat taatctatct cttttttttc
    15901 aagtggatac gaaaacagga aggactctta tctggctttt tcaccatatt tgctggctta
    15961 ctcttgattt ttgaagccta cttggtttgg aaatatggtt tggacaagtc cgttctaaaa
    16021 gggaccatgg ctcaggttgt gacagatctg actggttttc gaacgactag ttttgctgga
    16081 gggggcttga tcggggtcgc tctttatatt ccaacagctt ttctcttttc aaatatcgga
    16141 acttacttta ttggttctat cttgatttta gtgggttctc tcctagtcag cccttggtct
    16201 gtttacgata ttgctgaatt tttcagtaga ggctttgcca aatggtggga agggcacgag
    16261 cgtcgaaaag aggaacgctt tgtcaaacaa gaagaaaaag ctcgccaaaa ggctgagaaa
    16321 gaggctagat tagaacaaga agagactgaa aaagccttac tcgatttgcc tcctgttgat
    16381 atggaaacgg gtgaaattct gacagaggaa gctgttcaaa atcttccacc tattccagaa
    16441 gaaaagtggg tggaaccaga aatcatcctg cctcaagctg aacttaaatt ccctgaacag
    16501 gaagatgact cagatgacga agatgttcag gtcgattttt cagccaaaga agcccttgaa
    16561 tacaaacttc caagcttaca actctttgca ccagataaac caaaagatca gtctaaagag
    16621 aagaaaattg tcagagaaaa tatcaaaatc ttagaagcaa cctttgctag ctttggtatt
    16681 aaggtaacag ttgaacgggc cgaaattggg ccatcagtga ccaagtatga agtcaagccg
    16741 gctgttggtg taagggtcaa ccgcatttcc aatctatcag atgacctcgc tctagccttg
    16801 gctgccaaag atgtccggat tgaagcacca atccctggga aatccctaat cggaattgaa
    16861 gtgcccaact ccgatattgc cactgtatct ttccgagaac tatgggaaca atcgcaaacg
    16921 aaagcagaaa atttcttgga aattccttta gggaaggctg ttaatggaac cgcaagagct
    16981 tttgaccttt ctaaaatgcc ccacttgcta gttgcaggtt caacgggttc agggaagtca
    17041 gtagcagtta acggcattat tgctagcatt ctcatgaagg cgagaccaga tcaagttaaa
    17101 tttatgatgg tcgatcccaa gatggttgag ttatctgttt acaatgatat tccccacctc
    17161 ttgattccag tcgtgaccaa tccacgcaaa gccagcaagg ctctgcaaaa ggttgtggat
    17221 gaaatggaaa accgttatga actctttgcc aaggtgggag ttcggaatat tgcaggtttt
    17281 aatgccaagg tagaagagtt caattcccag tctgagtaca agcaaattcc gctaccattc
    17341 attgtcgtga ttgtggatga gttggctgac ctcatgatgg tggccagcaa ggaagtggaa
    17401 gatgctatca tccgtcttgg gcagaaggcg cgtgctgcag gtatccacat gattcttgca
    17461 actcagcgtc catctgttga tgtcatctct ggtttgatta aggccaatgt tccatctcgt
    17521 gtagcatttg cggtttcatc aggaacagac tcccgtacga ttttggatga aaatggagca
    17581 gaaaaacttc ttggtcgagg agacatgctc tttaaaccga ttgatgaaaa tcatccagtt
    17641 cgtctccaag gctcctttat ctcggatgac gatgttgagc gcattgtgaa cttcatcaag
    17701 actcaggcag atgcagacta cgatgagagt tttgatccag gtgaggtttc tgaaaatgaa
    17761 ggagaatttt cggatggaga tgctggtggt gatccgcttt ttgaagaagc taagtctttg
    17821 gttatcgaaa cacagaaagc cagtgcatcc atgattcagc gtcgtttgtc agttggattt
    17881 aaccgtgcga cccgtctcat ggaagagctt gagatggcag gtgtcattgg tccagctgaa
    17941 ggtaccaagc caagaaaagt attgcagcaa taaaaaatag cttctttcca aggttggaag
    18001 gagctatttt actggctatt gattactttt atactcttcg caaatctctt caaaccacgt
    18061 cagcttcgcc ttgccgtact caagtactgt ctacggctag cttcctagtt tgctctttga
    18121 ttttcattga gtattatttt ctgaagttgg agtattgggc tgtttttcat tttcagtggc
    18181 aggtttactt gtagcaggtg tagtagagtc ctgagttgct gttttctgat cttctttttt
    18241 ctcttccttg acgctagatt ttggcgtttc ttcttgttgt gttttttctt gagaagtgtt
    18301 attttcctta tttggagtag tattttcctg aggggattct ttttgaattt ctttgacaaa
    18361 ggttgtcgtc tggcttgtcg taggttcttt tttagtattt ttattattat tatccaaggc
    18421 gttcatgatc gtgatacccg cggtaatcaa accaaggata ctaccgatag tagtaatggt
    18481 tttttgaaaa acagtaaagc cttttttgat atgttctgtt ttcggttttg aagttctacg
    18541 atagttagac atacattctc tcctttgatt atgatttatt atactctgtt tctttaaaaa
    18601 aatcttaaaa aaagagaaat tgccctttct tgtcgcaggc tccgtttcat gatacaatag
    18661 aaggagtgat tttagaaagc gtgagaaaca tgatttactt tgataattcg gcgacgacca
    18721 ggccctatcc agaagccctt gaaacctata tgcaggtggc ttcaaaaatt ttaggaaatc
    18781 catctagtct ccatcgtttg ggagaccagg caacacgaat tttagatgct tcccgtcaac
    18841 agattgcaga tttaatcggt aagaaaagtg atgaaatctt ctttacatct ggtgggacag
    18901 aaggggataa ctggatcatc aagggagtag catttgaaaa agcccagttt ggcaagcaca
    18961 tcatcgtatc agccattgaa catccagcag ttaaggaatc agccctctgg ttgaaagctc
    19021 aaggttttga agtggatttt gctccagttg ataacaaagg atttgtggat gttgaggcgc
    19081 tagaagattt gataagacct gatacgaccc tcgtttccat catggctgtg aacaatgaaa
    19141 tcggctctat ccaacctatt gaggctattt cagaattctt ggcagacaag ccaactattt
    19201 ccttccacgt tgatgcggtt caggcgcttg ccaagattcc gactgaaaag tatctgacag
    19261 aacgagtgga tttcgcgact ttctctggtc acaagttcca cggaatccgt ggtgttggtt
    19321 ttatctatat caagtctggc aagaagatta cgcctctttt aacaggtggt ggtcaggaac
    19381 gtgattaccg ttcgacaact gaaaatgtgg caggaattgc agcgaccgct aaggctctcc
    19441 gtttatctat ggaaaagcta gatatcttta ggagcaagac tgggcagatg aaggcagtga
    19501 ttcgtcaagc acttctggac tatccggata tatttgtctt ttcagatgag gaagacttcg
    19561 cccctcatat tctgactttt ggaatcaagg gtgttcgtgg tgaggtcatt gttcacgcct
    19621 ttgaagacta tgatattttc atctcaacga cctcggcttg ttcgtccaag gctgggaaac
    19681 cagccggaac cctgattgct atgggagtgg acaaggataa ggctcagtca gctgtgcgtc
    19741 ttagtctaga ccttgaaaat gatatgagtc aggtcgagca gttcttgacc aagctaaaat
    19801 taatttacaa tcaaactaga aaagtaagat aggagcattc atgcagtatt cagaaattat
    19861 gattcgctac ggtgagctgt caaccaaggg caaaaatcgt atgcgtttca tcaataaact
    19921 tcgcaataat atttcagacg ttttgtctat ctatccccaa gttaaggtaa cagcagatcg
    19981 cgaccgtgcc cacgcttacc tcaatggagc agattacaca gcagtagcag aatcgctcaa
    20041 acaagtattt ggaattcaaa acttttcccc tgtttataag gttgaaaaat ctgtagaagt
    20101 tctgaagtct gctgtccaag agattatgca ggacatctac aaggaaggca tgacctttaa
    20161 aatctctagc aagcgtagcg accacacctt tgaattggac agtcgtgaac tcaaccaaac
    20221 gcttggaggg gctgtattcg aagccattcc aaacgtacaa gctcaaatga aaagtcctga
    20281 catcaatctt caggtggaga tacgtgaaga agcagcctat ctttcttatg aaaccgttcg
    20341 aggggcaggt ggattaccag tgggaacttc tggtaagggc atgctcatgt tgtcaggggg
    20401 aatcgattcc cctgtagctg gctatctagc gcttaaacga ggggtagata tagaggcagt
    20461 tcactttgcc agcccacctt acacgagtcc tggtgctctt aaaaaagccc aagatttgac
    20521 ccgtaaatta accaaatttg ggggaaatat ccagtttatc gaagttcctt ttacagagat
    20581 tcaagaggaa atcaaagcca aagcgccaga agcctacctt atgaccttga cgcgtcgttt
    20641 tatgatgcgt attactgacc gtattcgtga ggtacgaaat ggtttagtta tcatcaatgg
    20701 ggaaagtcta ggtcaagtag ccagccaaac ccttgaaagt atgaaggcta tcaatgctgt
    20761 taccaacact cccatcattc gtcctgtggt taccatggac aagttggaaa tcattgacat
    20821 cgcccaggaa atcgatacct ttgacatttc aatccaaccg tttgaagact gttgtactat
    20881 ttttgcacca gatcgtccaa aaacaaatcc taaaattaag aatgcggagc agtacgaagc
    20941 gcgtatggat gttgaaggct tggttgagcg agcagtggct ggaatcatga ttactgaaat
    21001 cacacctcaa gccgaaaaag atgaagttga tgacttgatt gacaatctgc tctaattcag
    21061 aaaatccaaa agaatagcga aaatcagtaa aaaaagttag ttttttctct aaaaacaggt
    21121 aaaaaactaa ctttttttat ttttatgata taatgatata aaattttgaa tatagagagt
    21181 tttctgacaa tgaatcaatc ctacttttat ctaaaaatga aagaacacaa actcaaggtt
    21241 ccttatacag gtaaggagcg ccgtgtacgt attcttcttc ctaaagatta tgagaaagat
    21301 acagaccgtt cctatcctgt tgtatacttt catgacgggc aaaatgtttt taatagcaaa
    21361 gagtctttca ttggacattc atggaagatt atcccagcta tcaaacgaaa tccggatatc
    21421 agtcgcatga ttgtcgttgc tattgacaat gatggtatgg ggcggatgaa tgagtatgcg
    21481 gcttggaagt tccaagaatc tcctatccca gagcagcagt ttggtggtaa gggtgtggag
    21541 tatgctgagt ttgtcatgga ggtggtcaag ccttttatca agcacaaaac aggttggttt
    21601 gatggcatga tgacgacagg ttgctctatg ggagcctatc atgcactcaa tttcttcctc
    21661 cagcatccag atgtctttac caaagtgatt gctctcagtg gtgtttacga cgcacgtttc
    21721 tttgtcggcg attactacaa cgatgatgct atttaccaaa actcgccagt agattatatt
    21781 tggaaccaaa acgatggctg gtttattgac cgttaccgtc aggcagagat tgtgctgtgt
    21841 acggggcttg gagcctggga acaagatggt ttaccatcct tttacaagct caaagaagcc
    21901 tttgaccaga aacaaattcc agcctggttt gctgaatggg gacatgatgt cgcccacgac
    21961 tgggaatggt ggcgtaaaca aatgccttat ttcctcggta atctctattt ataaaaggag
    22021 ttacctatga attaccttgt tatttctccc tactatccac aaaactttca acagtttacc
    22081 atcgaactag ctaataaagg catcacagtc ttgggaattg gtcaagagtc ttacgagcaa
    22141 ttggatgagc ccttgcgcaa tagcttgacc gagtattttc gtgttgataa tcttgagaac
    22201 atagatgaag tcaaacgtgc agttgctttt ctcttttata aacatggtcc aattgaccgc
    22261 atcgagtctc acaatgaata ctggcttgag ctagacgcaa cactcagaga acaattcaat
    22321 gtttttggtg ccaaaccaga ggatctcaaa aagacgaaat ataagtctga aatgaagaaa
    22381 cttttcaaaa aagcaggtgt tcctgtggta cctggagctg ttatcaagac ggaagcagat
    22441 gttgatcaag cagtgaaaga aatcggtctt ccaatgattg ccaaacctga taatggagtg
    22501 ggagcagccg caacctttaa acttgagaca gaagacgata tcaatcactt caagcaagaa
    22561 tgggaccatt caacccttta tttctttgaa aaatttgtca cttccagcga aatctgtacc
    22621 tttgacgggc tcgtggacaa ggatggaaag attgtcttct caacaacctt tgactacgcc
    22681 tatacaccgc ttgacctcat gatttataag atggacaatt cttattatgt gctcaaggat
    22741 atggatccta aactgcgcaa gtatggggaa gcaattgtca aagaatttgg tatgaaagaa
    22801 cggtttttcc atattgagtt cttccgtgag ggggacgatt atattaccat cgagtacaat
    22861 aaccgccctg caggtggttt taccattgat gtttataact ttgctcattc cttggacctt
    22921 tatcgtggct atgcagctat tgtcgcagga gaggagttcc cggcgtcaga ctttgaaact
    22981 cagtattgtt tggctacttc tcgccgtgca aatgctcact atgtttattc agaagaggat
    23041 ttgcttgcca aatatagcca gcagttcaag gttaaaaaag tcatgccagc tgccttcgcg
    23101 gaacttcaag gagattacct gtatatgctg acaactccga gtcgacaaga aatggatcag
    23161 atgattgctg atttcggaca acgtcaagaa taagaactat cggattaagg aaattcactc
    23221 ccttaatcct tttgttttgt ctggtaaaaa ataagagcat cctaacaagg tagctatcat
    23281 aaaacttgtt cgataactat ttgaagcagg attaggtggc tagaaattga attttaacat
    23341 ttcaatttag tcatagtatt gtgttttcgt atccttaaat cagctaaaag gatccatgac
    23401 gacacctata cgatatagtt ttcaggatac caaaccagtc tattaatact caatgaaaat
    23461 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cactgttttg aggttgtgga
    23521 tagaactgac agagtcagta tcatatacct acggcaaggt gaagctgacg tagtttgaag
    23581 agattttcga agagtataaa tcttattgat gaactgcttg cagtctgaga aaaaatgagc
    23641 ttggatatta tttccaaact cacttaaagt caatttcaat ccactagaac aagcctagta
    23701 cagttccatc gctttcaaca tccatgttga gagctgctgg acgttttgga agacctggca
    23761 tggtcataac atcaccagtt aaggcaacga tgaagcctgc acctaatttt ggtaccaatt
    23821 cacgaatggt aatttcaaag ttttctggtg ctccaagcgc atttggattg tctgagaaac
    23881 tgtattgagt tttagccata cagattggca atttgtccca accgttttga acgatttgag
    23941 caatttgtgt ttgagctttc ttctcaaagt tcactttgct accacgatag atttcagtga
    24001 caattttttc aatcttttct tggacagaaa gggcattatc gtacaaacgt ttatagttag
    24061 ctggattttc agcaattgtc ttaacaactg tttcggcaag tgctactcca ccttctgctc
    24121 catcagccca gacactagcc aattcaactg gtacatagat tgaggcacag agttctttta
    24181 agactgcaat ttcagcttct gtatcagata caaattcgtt aatagctaca actgctggaa
    24241 taccgaactt acggatattt tcaacgtggc gtttcaagtt agcaaaacct gcacgaactg
    24301 cctctacatt ttcttcagtc agagcgtctt tagccacacc accattcatc ttaagggcac
    24361 gaagggttgc gacaatgaca actgcatctg gagatgttgg caagtttggt gtcttgatat
    24421 caaggaattt ctcagcacca aggtccgcac caaaaccagc ttcagtaaca gtgtaatcag
    24481 ccaagtgaag ggctgttgtc gtcgccaaaa cagagttaca gccatgagcg atattggcaa
    24541 atggaccacc gtgtacaaag gcaggtgtac cgtaaattgt ctgaaccaag tttggcttaa
    24601 tagcatcctt caaaatcaaa gccaaggcac cctcaacctg caaatcacct acagaaacag
    24661 gcgtacggtc atagcgataa ccaataacga tattcgccaa acgacgtttc aagtcctcga
    24721 tgtccgttgc caagcaaaga attgccatga tttctgaagc aactgtaata tcaaaaccat
    24781 cctcacgtgg aataccgttt agaggaccac caagaccaac agtcacatgg cggagcgcac
    24841 ggtcgttcaa gtccacaacg cgtttccaga ggatacgacg ttgatcaatt tccagctcat
    24901 tcccttggtg caagtggttg tcaatcaagg cagaaagggc attgttggca gttgtaatag
    24961 catgcatatc tccagtaaag tggaggttga tgtcttccat tggcagaact tgtgcatacc
    25021 caccaccagc agcaccaccc ttgatcccca tgactggacc aagagacggt tcgcggatag
    25081 caatcatggt tttcttgcca atcttgttca aggcatccgc aagaccaatg gtaagcgtcg
    25141 actttccttc acctgcaggt gttgggttga tggcagtaac caagatcaat ttaccgactg
    25201 gattgctctc aactgcacga attttatcaa agctgagttt agccttgtac tttccgtaca
    25261 actccaaatc gtcataagaa ataccaagtt tctctacaac atcaacaatt ggcttcaact
    25321 caatactctg tgcgatttca atatctgttt tcattcaaaa ttcctctaac ctcttatatg
    25381 ataattcatt atatcacaaa acaagatttt taacatccta aaactctcta aacgttcgta
    25441 aatatctctg tttttaaggc ttttagagtc ctttcttaaa ttttatatgg ctttatagtt
    25501 tgaaactata gtaaatcttc gtttttacca aaaatttatc actttcattt tacttaccgc
    25561 ttatttttgt gtacaatagt gctatgaaaa ttttagttac atcgggcggt accagtgaag
    25621 ctatcgatag cgtccgctct atcactaacc attctacagg tcacttgggg aaaattatca
    25681 cagagacttt gctttctgca gggcatgaag tttgtttaat tacgacaaaa cgagctctga
    25741 agccagagcc tcatcctaac ctaagtattc gagaaattac caataccaag gaccttctaa
    25801 tagaaatgca agaacgtgtt caggattatc aggtcttgat ccactcaatg gctgtttctg
    25861 actacactcc tgtttatatg acagggcttg aggaagttca ggctagctcc aatctaaaag
    25921 aatttttaag caagcagaat catcaggcca agatttcttc aactgatgag gttcaggttt
    25981 tgttccttaa aaagacaccc aaaatcatat ccctagtcaa ggaatggaat cccactattc
    26041 atctgattgg tttcaaactg ctggttgatg ttaccgaaga tcatctggtt gacattgcac
    26101 gaaaaagtct tatcaagaat caagcagatt taatcatcgc gaatgacctg actcaaattt
    26161 cagcagatca gcaccgagct atatttgttg agaaaaatca gcttcaaaca gtccagacta
    26221 aagaagaaat tgcagaactc ctccttgaaa aaattcaagc ctatcattct tagaaaggaa
    26281 aactatggca aacattctct tggctgtaac gggttcaatc gcctcttata agtcggcaga
    26341 tttagtcagt tctctaaaaa aacaaggcca tcaagtcact gtcttaatga ctcaggctgc
    26401 tacagagttt atccaacctt tgacactaca ggtactctca cagaatcctg tccacttgga
    26461 tgtcatgaag gaaccctatc ctgatcaggt caatcatatc gaacttggaa aaaaagcaga
    26521 tttatttatc gtggtacctg caactgctaa cactattgca aaactagctc acggatttgc
    26581 ggacaacatg gtaaccagta cagctctagc cctaccaagt catattccca aactaatagc
    26641 tcctgctatg aatacaaaaa tgtatgacca tccagtaact cagaataatc tgaaaacatt
    26701 agaaacctac ggctatcagc tgattgctcc taaggaatcc ctactagctt gtggagacca
    26761 cggacgagga gctttagctg acctcacaat tattttagaa agaataaagg aaactatcga
    26821 tgaaaaaacg ctctaatatt gcacccattg ctatcttttt tgctaccatg ctcgtgatac
    26881 actttctgag ctcacttatc tttaaccttt ttccatttcc aatcaaaccg accattgttc
    26941 atattcctgt cattattgcc agcattattt atggtccacg agttggggtt acacttggat
    27001 ttttgatggg attacttagc ttgacggtta acacgattac gattctaccg acaagctacc
    27061 tcttctctcc cttcgtacca aacggaaaca tctactcagc tatcattgcc atcgtcccac
    27121 gtattttgat tggtttaact ccttacttag tctataaact gatgaaaaac aagactggtc
    27181 tgattttagc tggagccctt ggttccttga caaatactat ctttgtcctt ggaggaatct
    27241 tcttcctatt tggaaatgtt tataatggaa atatccaact tcttctggca accgttatct
    27301 caacaaattc aattgctgaa ttggtcattt ctgcaattct aaccctagcc attgttccac
    27361 gactacaaac cttgaaaaaa taaaaacaat ctccgctttc aaacctgaag gtggagattt
    27421 tgctctatac agtttctttt taatgaaatc tttactatag taaaacgaaa taagaacagg
    27481 acaaatcgat caggacagtc aaatcgctaa caatgtttta gaagtagagg tggactattc
    27541 tagtttccat ctactataac ttttaactaa aaaatgatct ataaacccaa gtaaattctt
    27601 gctttattgt ctggtttatt gtaccatact agtgtatatg cagttaaaaa ggagattctt
    27661 gtgaatacac ggaaaaagac acaatttatg acaatgacag cccttttaac ggctattgcg
    27721 attttgattc caattgttat gcctttcaag attgtcattc cacctgcttc ctatactttg
    27781 gggagccaca tcgctatttt tatagccatg ttcttgtcgc ccttgatggc agtttttgtc
    27841 atcctagcct ctagttttgg atttttgatg gctggctatc ccatggttat cgtttttcgg
    27901 gctttttccc atatatcttt tggtgcttta ggagctcttt acctacaaaa attccccgat
    27961 accctagata aaccaaaatc ttcctgggtt ttcaattttg ttttggctgt tgttcatgcc
    28021 cttgctgaag tattagcctg tgtccttttt tacgcaactt cgggtaccaa tgtagaaaat
    28081 atgttctatg ttctatttgt actagttgga tttggcacaa ttatccatag tatggtagac
    28141 tatacattag cactagctgt ctataaagtg cttcgaaaac gccgttaaaa ggaaaagcta
    28201 tgacaaaaga tcgcaaacaa gccctgctcc aactcttgaa agaagctcct aaagccctta
    28261 atggccaaag tttggcggaa cattttcatg tcacacgtca ggtcattgtg caggatattg
    28321 caattttgag agccgatggc gctcctatcc tatccaccaa tcgtggctac atctataagc
    28381 aaattgatac caatccttat gttcacaaac ttttcaaagt gaaacatgaa gttgaagaaa
    28441 tcggtcagga actccttgct attgtcgata atggtgggca tgtccagaat accttgattg
    28501 accatcccgt ttatggagaa attgaaacct tgcttaaact gtcttgtcgc agagatgtgc
    28561 aacattttct agaacaagtc gagcattctg actttagacc tctatctgaa ttgacagatg
    28621 gcatccatta ccacctagtc gaagccgaaa cacaacaaga cctccactat atcgaggagg
    28681 ccttggatca gctaggttat ttagtaaaag actagaagat tttcttttcc caatcgtctt
    28741 ctgtacggcg agggtagaaa aactctgact tgtcgggagc ttccatcatt tccatcaatg
    28801 gtagcatatc ataggccaga tccaagtttg gaatctggtc tttttgcacc caagaaactt
    28861 ctccttcatc tgaagaccga aggctaccag agaactcagt cgccttataa caaatgacaa
    28921 tatagcgccc acctgtatct agtggccaat ttttaatgcc gacaagttga ggattttgga
    28981 tagtcaaccc tgtttcttcg tagatttcac gaatgacaga ctccgcaaaa gcctcatcat
    29041 tttctacatg acctccagga aaggcataac cagaccagcg attgttttca ggggcgcgat
    29101 actgcatcac cacgcgctga gtttcgaggt cttcaatcag acagatattt gttaaaattg
    29161 ttaattggga acgggacata aatttactcg ctttctaatt tattaaatt
//
LOCUS       DAVKBK010000022        29134 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVKBK010000022 DAVKBK010000000
VERSION     DAVKBK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.022"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            226..6660
                     /locus_tag="VWX69_001082"
     CDS             226..6660
                     /locus_tag="VWX69_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU9192440.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            7292..7767
                     /locus_tag="VWX69_001083"
                     /pseudo
     CDS             7292..7767
                     /locus_tag="VWX69_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            7805..8107
                     /locus_tag="VWX69_001084"
     CDS             7805..8107
                     /locus_tag="VWX69_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9192441.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEARPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            8115..8916
                     /locus_tag="VWX69_001085"
                     /pseudo
     CDS             8115..8916
                     /locus_tag="VWX69_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            8965..9429
                     /locus_tag="VWX69_001086"
     CDS             8965..9429
                     /locus_tag="VWX69_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU9192442.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            9586..10011
                     /gene="lacA"
                     /locus_tag="VWX69_001087"
     CDS             9586..10011
                     /gene="lacA"
                     /locus_tag="VWX69_001087"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU9192443.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            10042..10557
                     /gene="lacB"
                     /locus_tag="VWX69_001088"
     CDS             10042..10557
                     /gene="lacB"
                     /locus_tag="VWX69_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU9192444.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            10568..11497
                     /locus_tag="VWX69_001089"
     CDS             10568..11497
                     /locus_tag="VWX69_001089"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU9192445.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQDLYDQLIVKEV"
     gene            11499..12479
                     /gene="lacD"
                     /locus_tag="VWX69_001090"
     CDS             11499..12479
                     /gene="lacD"
                     /locus_tag="VWX69_001090"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU9192446.1"
                     /translation="MALTEQKRARLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            12714..13550
                     /locus_tag="VWX69_001091"
     CDS             12714..13550
                     /locus_tag="VWX69_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9192447.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAEHQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALAQGRYKDSNLPDISTKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILKNVEEVLKEYAIQRTKENNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            13585..13902
                     /locus_tag="VWX69_001092"
     CDS             13585..13902
                     /locus_tag="VWX69_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9192448.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFAKADILVE
                     EAGSCIAEAHHAQTSLLTKEAAGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            13902..15593
                     /locus_tag="VWX69_001093"
     CDS             13902..15593
                     /locus_tag="VWX69_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9192449.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDDVVNLLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            15808..17214
                     /gene="lacG"
                     /locus_tag="VWX69_001094"
     CDS             15808..17214
                     /gene="lacG"
                     /locus_tag="VWX69_001094"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9192450.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            17304..17516
                     /locus_tag="VWX69_001095"
     CDS             17304..17516
                     /locus_tag="VWX69_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU9192451.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(17795..18556)
                     /locus_tag="VWX69_001096"
     CDS             complement(17795..18556)
                     /locus_tag="VWX69_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9192452.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(18844..19806)
                     /gene="nrdF"
                     /locus_tag="VWX69_001097"
     CDS             complement(18844..19806)
                     /gene="nrdF"
                     /locus_tag="VWX69_001097"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU9192453.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(19994..22153)
                     /gene="nrdE"
                     /locus_tag="VWX69_001098"
     CDS             complement(19994..22153)
                     /gene="nrdE"
                     /locus_tag="VWX69_001098"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU9192454.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIDHNYIETAFIKKYRPEFLEELSQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLESMEDRVFFNALYFADGNESVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVELEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVDFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYAKGSYFDKYVTGEFVPKSDRVKELFKDVFIPSAADWAELRDKIQ
                     ADGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKKENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(22234..22452)
                     /gene="nrdH"
                     /locus_tag="VWX69_001099"
     CDS             complement(22234..22452)
                     /gene="nrdH"
                     /locus_tag="VWX69_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU9192455.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVEYKEINLDEQPEYIDQVKE
                     LGFSAAPIIQTPTEVFSGFQPGKLKQLA"
     gene            22802..23065
                     /locus_tag="VWX69_001100"
     CDS             22802..23065
                     /locus_tag="VWX69_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU9192456.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            23071..24804
                     /gene="ptsP"
                     /locus_tag="VWX69_001101"
     CDS             23071..24804
                     /gene="ptsP"
                     /locus_tag="VWX69_001101"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU9192457.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETISVEDTNAEEARL
                     DVALEASQNELSLIREKAVGTLGEEAAQVFDAHLMVLSDPELIGQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEVVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            25059..27509
                     /gene="phtA"
                     /locus_tag="VWX69_001102"
     CDS             25059..27509
                     /gene="phtA"
                     /locus_tag="VWX69_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEU9192458.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            27667..>29134
                     /locus_tag="VWX69_001103"
     CDS             27667..>29134
                     /locus_tag="VWX69_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9192459.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         9841 a         4959 c         5902 g         8432 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 ttagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca gttattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 acatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgca gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctattcgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagact taaagaaact cattaaaaag
     4441 aaatttagag aagttgatga ttttacaagt gaaactggta agagaataga ggaatacgat
     4501 tataaatacg atgataaggg aaatattatt gcttatgacg atggtagtgc cttacaatat
     4561 gaaactgaaa aacttgacga aataaaatca aaaatttatg gcgttctaag cccatctaaa
     4621 gatggacact ttgaaattct tggaaagata agcaatgttt ctaaaaatgc caaggtatat
     4681 tatggaaata gctataaatc gatagaaatc aaagcgacta agtatgactc acattcaaaa
     4741 acgatgacat ttgatttata cgctaatatt aatgatattg tggatggatt agcttttgct
     4801 ggagatatgc ggttttttgt taaagatgat aatcgaataa aagctgaaac taaaattaga
     4861 atgcctgaaa aaaataagga aactaaagca gaatatccct atgtatcaag ttatgggaat
     4921 gtaatcgaat taggagaagg agatctttca aagaacaaac cagacaattt aactaaaatg
     4981 gaatctggta aaatctattc tgattcagaa aaacaacaat atctgttaaa ggataacatc
     5041 attctaagaa aaggctatgc actaaaagtg actacctata atcctggaaa aacggatatg
     5101 ttagaaggaa atggagtcta tagcaaggaa gatatagcaa aaatacaaaa ggccaatcct
     5161 aatctaagag tcctttcaga aacaacaatt tatgctgata gtagaaatgt tgaagatgga
     5221 agaagtaccc aagctgtatt aatgtcggct ttggacggct ttaacattat aaggtatcaa
     5281 gtgtttacat ttaaaatgaa cgataaaggg gaagctatcg ataaagacgg aaatcttgtg
     5341 acagattctt ctaaacttgt attatttggt aaggatgata aagaatacac tggagaggat
     5401 aagtccaatg tagaagctat aaaagaagat ggctccatgt tatttattga taccaaacca
     5461 gtaaaccttt caatggataa gaactacttt aatccatcta aatctaataa aatttatgta
     5521 cgaaatccag aattttattt aagaggtaag atttctgata agggtggttt taactgggaa
     5581 ttgagagtta atgaatcggt tgtagataat tatttaatct acggagattt acacattgat
     5641 aacactagag attttaatat taagctgaat gttaaagacg gtgacatcat ggactgggga
     5701 atgaaagact ataaagcaaa cggatttcca gataaggtaa cagatatgga tggaaatgtt
     5761 tatcttcaaa ctggctatag cgatttgaat gctaaagcag ttggagtcca ctatcagttt
     5821 ttatatgata atgttaaacc cgaagtaaac attgatccta agggaaatac tagtatcgaa
     5881 tatgctgatg gaaaatctgt agtctttaac atcaatgata aaagaaataa tggattcgat
     5941 ggtgagattc aagaacaaca tatttatgta aatggaaaag aatatacatc atttgatgat
     6001 attaaacaaa taacagacaa gacactaaac attaagattg ttgtaaaaga ttttgcaaga
     6061 aatacaaccg taaaagaatt cattttaaat aaagatacgg gagaggtaag tgaattaaaa
     6121 cctcataggg taactgtgac cattcaaaat ggaaaagaaa tgagttcaac gatagtgtcg
     6181 gaagaagatt ttattttacc tgtttataag ggtgaattag aaaaaggata ccaatttgat
     6241 ggttgggaaa tttctggttt cgaaggtaaa aaagacgctg gctatgttat taatctatca
     6301 aaagatacct ttataaaacc tgtattcaag aaaatagagg agaaaaagga ggaagaaaat
     6361 aaacctactt ttgatgtatc gaaaaagaaa gataacccac aagtaaacca tagtcaatta
     6421 aatgaaagtc acagaaaaga ggatttacaa agagaagatc attcacaaaa atctgattca
     6481 actaaggatg ttacagctac agttcttgat aaaaacaata tcagtagtaa atcaactact
     6541 aacaatccta ataagttgcc aaaaactgga acagcaagcg gagcccagac actattagct
     6601 gccggaataa tgtttatagt aggaattttt cttggattga agaaaaaaaa tcaagattaa
     6661 gacaaaagct atagaaaaaa atggtttatg tactgagatt agatagtgag gtgatgacat
     6721 agttttgtga aaacggccat ttataactca attatttagt ttacttcact tcactattga
     6781 tactatttgg agttattaac ggacttagtt tagataacta atgaattgat tgaaagggtt
     6841 agtattgaca atattggtca tattgattag aaaatagagt ctatcaaaat ttaaaggcta
     6901 atagaggtga tgagacaatt tcaaggaatt aagtagcgtt tggttgctta attccttttt
     6961 atttggaagg aagtttttcg taaccgccca ataacgaagt ctattggacg gttacgatat
     7021 gatcactgac ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag caacctgcgg
     7081 ctagcttcct agtttactct ttgattttca ttgagtatta gaacagaaaa aatgcttgga
     7141 gtatttgttt gtgtgtttat ttttatataa caaactataa acacaacaaa aatataaaaa
     7201 aagagacaaa aaagaacaga aagtaattaa caacgatttc atatagtgtt atacttatag
     7261 cataaagtta atggaaagaa gggaaaacct tatggtatta gattatttct ttgacaaaaa
     7321 ccttgtgttt tgcttagaag cggataatca agaataactc tttgatcagg tagcaagctt
     7381 gttggaggaa cgagaaattg taactccaac ttatcgtgaa gctttgatca cgcgtgaaaa
     7441 gtcatttcca actggtttag atatggaatt tctaggaaag gacttgcaaa tgtaatgatt
     7501 cctcacacag atattgttca taatctagct gagaaagtgg tggttgttcg attagagaaa
     7561 ccggtgactt tccataatat gattgcgcca ggtaaggaag tagaagtatc cttgctcttc
     7621 tttatcatca ataattcaag ttcaagtcaa acgaacattc ttgctcagtt gatggacttt
     7681 ttcacaggaa atggacatct tgaagaccta tcaaaaattt ccgaaccaga aaaactttat
     7741 gcttatatag atgaagcaat cgcttaatct tgtctattaa aaaataaaat cggaggaagt
     7801 ctatatgatt aaaattcttg ctgcctgcgg tgcaggtgtt aactcaagtc accaaattaa
     7861 aagtgctcta gaagaagaac tttcaaaccg tggttacgat gttcactgtg atgcagttat
     7921 ggtgaaagat gtaaacgaag accttatgaa aggttacgat atctttacac caatcgctgc
     7981 aacagacctt ggttttgaac caggtatccc agttatcgaa gctaggccaa tcttattccg
     8041 tatcccagca atgagcgttc cagtatttga caatattaga cttcctgcga aacaaaatat
     8101 ggtatagtag ttctatgaat gatgaagcaa gtaaacaact aactgatgca cgatttaagc
     8161 gtcttgttgg tgttcagcgt accacttttg aagagatgtt agctgtatta aaaacagctt
     8221 atcaacttaa acacgcaaaa ggtggacgaa aacctaaatt aagcctagaa gaccttctta
     8281 tggccactct tcaatagtgc gagaatatcg aacttatgaa caaattgcgg ctgattttgg
     8341 tattcacgaa agcaacttta tccgtcggag ccaatgggtt gaagtaactc ttgttcaaag
     8401 tggtgttacg gtttcaagaa ctcctctcag ctctgaggac acggtaatga ttgatgcgac
     8461 ggaagtacaa atcaatcgcc ctaaaaaaga attagcgaat gattctggta aaaagaaatg
     8521 ccacgctatg aaggctcaag cgattgtcac aagtcaaggg agattgtttc tttggatatc
     8581 actgtgaact attgtcatga tatgaagttg ttcaaaatga gtcgcagaaa tatcggacaa
     8641 gctggtaaaa tcttggctga cagtggttat caagggctca tgaagatata tcctcaagta
     8701 caaactccac gtaaatccag caaactcaag ccgctaacag ttgaagataa aacctataac
     8761 catgcgctat ctaaggagag aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt
     8821 aaaatgattt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
     8881 attgctggca ttatcaatca tgaactagga ttctagtttt gcaggaagtc taataaagaa
     8941 actagcaagg tcaggcctta ctttattggt ggacatccag gatttaattg tcctctactt
     9001 gatgatgaag tctatgaaga ttattatcta gagtttgaga aagaagagac ttgctctgtt
     9061 ccacgtcctt tcccagaaac aggtatgttg gatttccaag atagaagtcc atggctagag
     9121 ggacaaaaag aaatagatct tagttatgat cttttcagca aagatgcagt gactttggat
     9181 gaattgcaat ctcgaacaat tgcccttcgt tctcttaaac atgatagggg attgaaagtg
     9241 cattttgcag aatttccaaa cctcatcatc tggtcaactt tgaacaaggg acctttcatt
     9301 acctttgaac catggtctgg cttgtcaaca ttccttgaag aaggagatca tttagaagat
     9361 aagaagaatg tttgtctctt agaagccaat caggttgaag aattagggtt tgagatagaa
     9421 gttttataaa aaagtaaaaa ataaataaca aaaacaaaca caaactgttg acttcttcaa
     9481 acaatagtag tatattatgt ttgtgaggac taattgactg ttttttaaag acagccaata
     9541 cactgctgga atccagcata gaaaaaataa aaaggagtat acaatatgtc tattgttatc
     9601 ggtgcagatg ctgcaggttt gagattgaaa gaagttgtga aagacttctt agaaaaagaa
     9661 aacttccacc ttgtggatgt tacagctgaa ggtcaagact ttgttgatgt gactctcgct
     9721 gttgctgcag aagtaaacaa agaagaacaa aaccttggta tcgtgattga tgcttatgga
     9781 gctggtccat ttatggttgc aactaagatc aaaggaatgg ttgctgcaga agtttctgat
     9841 gaacgttcag cttatatgac tcgtggccac aacaactcac gtatgatcac tatgggtgca
     9901 caacttgttg gtgatgaatt ggctaaaaac atcgctaaag gatttgttaa tggtaaatac
     9961 gacggtggtc gtcaccaaat ccgggttgac atgttgaaca aaatgggcta attagattat
    10021 agtaagaaag gtaagttaaa aatgagaatt gcaattggat gtgaccacat cgtaacagat
    10081 gaaaaaatgg cggtttcaga atttttgaaa tcaaaaggat atgaagtcat tgactttggt
    10141 acatatgacc atacacgtac tcactaccca atctttggta aaaaagtagg ggaagctgta
    10201 actagcggtc aagctgatct tggagtatgt atctgtggta ctggtgttgg tatcaacaac
    10261 gctgtaaata aagttccagg tgttcgttct gccttggttc gtgatatgac aacagccctt
    10321 tatgctaaag aacaattgaa cgctaacgtt attggttttg gtggtaaaat tactggtgaa
    10381 ttgcttatgt gtgatatcat cgaagctttc atccatgctg aatacaaacc aactgaagaa
    10441 aacaaaaaat tgattgcgaa aattgaacat gttgaaagtc acaatgctca acaaacagac
    10501 gcaaacttct tcactgaatt ccttgaaaaa tgggatcgcg gagaatacca cgactaagag
    10561 gtaacctatg attttaacag ttacaatgaa cccatccatt gatatttcct atcccttgga
    10621 tgagttgaag attgatactg tcaatcgtgt ggtggatgta accaaaacgg ctggtggtaa
    10681 gggactcaat gttacccgag tactttcaga atttggcgat tctgttcttg ctactggttt
    10741 agtgggtggc aaacttggtg agtttttggt tgaacatatc gataatcaag taaagaaaga
    10801 tttcttctca attcagggag aaactcgtaa ctgtatcgct attctccacg gagacaacca
    10861 aacagaagtt cttgaaaaag gtcctgaagt attggaacag gaaggtcaag actttttgga
    10921 acatttcaaa aaactcttgg agtcagttga agtagtggcc atctcaggta gtctgccagc
    10981 tggccttcca gttgattact atgcgagctt ggtagaactt gctaatcaag ctggcaagcc
    11041 tgtagtcttg gactgctcag gtgcagcact tcaggctgtt cttgaatcac cccataaacc
    11101 aacagtcatc aaaccaaata atgaagaatt gtctcagctt cttggaagag aagtttctga
    11161 ggatttggat gaattaaaag aagtacttca agaacctttg tttgcaggga ttgaatggat
    11221 tatcgtttca cttggtgcca acggtacttt tgccaaacat ggtgacactt tctacaaggt
    11281 agatattcct agaattcagg tggtaaatcc tgttggatct ggagactcta ctgtggcagg
    11341 aatttcttca ggacttcttc acaaagaatc ggatgcagaa ttactcatca aggcaaatgt
    11401 ccttggtatg ctcaatgctc aagaaaaaat gactggtcat gtcaacatgg ccaactatca
    11461 agatctatat gatcaattaa tagtaaaaga ggtataaaat ggctttaaca gaacaaaaac
    11521 gtgcacgctt agaaaaactt tctgacgaaa atggtatcat ctcagctctt gcatttgacc
    11581 aacgtggtgc tttgaaacgc ctcatggctc aacaccaaac agaagaacca actgtggctc
    11641 aaatggaaga actgaaagtc ttggtagcag atgaattgac taaatacgct tcatctatgc
    11701 ttcttgatcc tgaatatggg cttccagcga ctaaagctct tgatgaaaaa gctggtcttc
    11761 ttcttgctta tgaaaaaaca ggttatgaca caacaagtac aaaacgcttg ccagactgct
    11821 tggatgtttg gtctgcaaaa cgtattaaag aagaaggtgc agatgcagtt aaattcttgc
    11881 tttactatga cgtagatagc tcagacgaac tcaaccaaga aaaacaagct tacatcgaac
    11941 gtatcggttc tgagtgtgtg gctgaagata ttccattctt ccttgaaatc cttgcttacg
    12001 atgaaaaaat tgctgatgca ggttctgtag aatacgcgaa agtaaaacca cacaaagtta
    12061 tcggtgctat gaaagtcttc tcagatccac gttttaacat tgatgtcttg aaagtagaag
    12121 ttcctgttaa cattaaatat gttgaaggct ttgctgaagg tgaagtagtt tatacacgtg
    12181 aagaagcagc agccttcttt aaagcccaag atgaagcaac taacttgcca tacatctact
    12241 tgagtgctgg tgtatcagct aaactcttcc aagatactct tgtatttgct catgaatcag
    12301 gtgcaaactt taacggagtt ctttgtggcc gtgctacatg ggctggatca gttgaagcat
    12361 acatcaaaga tggtgaagca gcagcacgtg aatggcttcg cacaactgga tttgaaaata
    12421 tcgatgagct caataaagtt cttcaaacaa cagcgacttc atggaaggaa cgcgtgtaag
    12481 aaagtccttc tagtttcgga acatgaatct aaaaaatttt ttaaaaaagt tacatgtaaa
    12541 ggtttacaaa ataacttact tgtgctatac ttaaatcaca agttaataca aggtgagtgt
    12601 tactaagtaa tattaggcat gatcacaggt gaattagaaa tcggctgatt ttctagttca
    12661 tttgtggtca ttttttgtac tcatatacct ttaagatata aaaggaggtt gacatgtatc
    12721 gaattctaaa tccaatgaat cacaatgtct cgcttgtcag aaatgataaa ggagaagagg
    12781 tgattgtaat tggtaagggg attgcattcg gaaagaagaa gggggatttg attgctgaac
    12841 atcaggttga gaaaatcttt cggatgaaga ccgaagagtc cagagaaaac tttatggctc
    12901 tcctcaaaga tgttccgctt gattttatca cagtgaccta tgagattatt gataagcttt
    12961 ccaagaaata tcattatccg attcaagagt atctctatgt aaccttgaca gatcatattt
    13021 actgttctta ccaagctcta gcacaaggaa ggtataagga tagtaatctg ccagatattt
    13081 ccactaagta tcctgtcgct tttcaaatcg caaatgaagc ttttgaaatt taccgtcaga
    13141 agctagcaga tcatttccct gaggatgaaa ttattcggat tgcttatcat ttcatcaatg
    13201 ccgaaggtga aaatgaagtg gaacttgtgg agtcgattga taagaggaaa gaaattctca
    13261 agaatgttga ggaagttcta aaggaatatg caattcaacg aaccaaagag aataatcatt
    13321 tctatgatcg ttttatgatt catctgaatt atttcttgga ttatttagac agatctaggg
    13381 atgataacca atcgcttctt gatatggaag atcatatcaa acaatcctat ccaaaagcgt
    13441 tcgagattgg ttccaaaatc tatgatgtga ttacacaaca tacgggtctt gatttgtata
    13501 aaagtgaacg agtttatcta gttctacata tccaacgttt attatcataa aaattattta
    13561 aaattatata aggagaattc tatcatgaat agagaagaag taacattgtt aggttttgaa
    13621 atcgtagcct atgctggcga tgctcgttca aaattattgg aagccttgaa agctgctgaa
    13681 gccggcgatt ttgcgaaagc ggatatctta gtcgaggaag ctggtagctg tatcgctgag
    13741 gctcaccacg cacaaacaag tctattgact aaggaagcag ctggcgaaga tttggcttat
    13801 agtgtaacca tgatgcatgg tcaagaccac ttgatgacaa ctatcttgtt aaaagatttg
    13861 atgcatcact taattgaact ttacaagaga ggagttaagt aatgaacaaa ctaattgcat
    13921 ttatcgagaa aggaaagcct ttctttgaga aattatctcg taatatctat cttcgtgcta
    13981 ttcgtgatgg tttcattgca ggtatgcctg ttattctctt ctcaagtatc tttatcttga
    14041 ttgcttttgt acccaactca tggggcttta aatggtctga tgatgttgtt aatctcctca
    14101 tgaaacctta tagctattca atggggattc tagctctctt ggtagctggt acaacagcta
    14161 agtcattgac cgactcagta aaccgtagca tggagaaaac aaatcaaatc aactatatgt
    14221 caacattgtt ggcagcaatt gttggtttgt tgatgttggc agctgaccct atcgaaaatg
    14281 gtctagctac tggattcttg gggacaaaag gtttgctttc agcattcctt gctgcctttg
    14341 ttactgtagc aatctataag gtttgtgtta agaacaacgt cactattcgt atgcctgacg
    14401 aagttccacc aaatatctca caagtcttta aagatgtgat tccattcact ctatctgttg
    14461 tttctcttta tgctcttgac ttattagcac gtcattttgt tggtgcaagt gtggcagaat
    14521 caatcggtaa attcttcgca ccactcttct ctgcagctga tggctatctt ggtattacca
    14581 ttatctttgg tgcctttgcc ttcttctggt ttgttggtat ccatggtcca tctatcgttg
    14641 aaccagccat cgcagctatt acctatgcaa atgctgaagt caacttgaac cttcttcaac
    14701 aagggatgca cgctgataag attcttactt ctggtacaca aatgtttatc gttaccatgg
    14761 gtggtactgg tgcgacactg gttgttccat tcatgttcat gtggttaaca aaatcaaaac
    14821 gtaaccgtgc aatcggacgt gcttcagtag ttcctacctt ctttggtgta aatgaaccaa
    14881 tcttgtttgg tgcaccactt gtattgaacc caatcttctt cattccattt atctttgctc
    14941 caatcgcaaa cgtttggatc tttaaattct tcattgaaac tcttggaatg aattcattta
    15001 ctgctaatct accatggaca actccagctc cactgggtct agtgcttggt acgaacttcc
    15061 aagtgctatc attcattctt gctgctcttc taattgtggt tgacgtagtc atttactatc
    15121 cattccttaa agtctatgat gaacaaattc ttgaagaaga acgttcaggt aaatctaatg
    15181 atgaattgaa agaaaaagtt gctgcaaact tcaacactgc aaaagcggat gctattcttg
    15241 aaaaagcagg tgtcgatgca gcacaaaata ccatcactga agaaacaaat gtcctcgttc
    15301 tctgtgctgg tggaggtaca agtggactcc ttgcaaatgc tttgaataag gcagcagcag
    15361 aatacaatgt ccctgtgaaa gcagcagcag gcggctatgg tgctcaccgt gaaatgttac
    15421 cagagtttga tttggttatc cttgctcctc aagttgcttc aaactttgaa gatatgaagg
    15481 cagaaacaga taagctcggt attaaactag cgaaaacaga aggcgctcaa tacatcaaat
    15541 taactcgtga tggaaaaggt gccctagcat tcgtacaaga acaattcgat taaggctagg
    15601 aactgtgaaa cagtctccta tcgttacgga aatcgctatg gcgaatttcc taatcgcctt
    15661 attaattcgt cggtaaaaag atatcgtttt tacctcctca tgtcacaatt cggtgacttg
    15721 gtacaagaag tgagatggag aaggatggct cactgactcc tctcctctca cttttacttt
    15781 atttaaatca agaaataggt gaaaaaaatg acaaaaacac ttccaaaaga ctttattttt
    15841 ggtggcgcaa cagctgccta tcaagcagaa ggtgctacac atactgatgg taaaggacca
    15901 gtagcgtggg ataaatatct tgaagataac tactggtaca ctgcagaacc agccagtgat
    15961 ttttacaatc gatatccagt tgatctcaag ctagcagaag agtatggtgt caatggcatt
    16021 cgaatttcta ttgcctggtc acgtattttc ccgactggtt atggtcaagt aaatgctaaa
    16081 ggtgttgagt tttatcataa tttatttgca gagtgtcaca aacgtcatgt tgagcccttt
    16141 gtaactcttc atcactttga cacgccagaa gctctccact caaatggaga cttcttaaac
    16201 cgtgaaaata tcgaacattt tgtagactac gctgccttct gttttgaaga atttccagaa
    16261 gtaaactatt ggacaacctt caatgaaatt ggaccaatcg gtgatggtca atatttggtt
    16321 gggaaattcc ctccaggtat ccagtacgac cttgccaaag tctttcaatc acaccacaat
    16381 atgatggtgt ctcatgcatg cgcggtaaaa ttgtacaaag agaaaggcta taaaggggaa
    16441 attggtgttg ttcacgccct gcctactaaa tatcctctag atcctgaaaa tccagcagat
    16501 gttcgtgcag cagagttgga agatatcatc cacaataaat tcatcttaga cgcaacttat
    16561 ctaggtcgct attcagctga aaccatggaa ggtgtcaacc atatcttatc agtcaatggt
    16621 ggtagtttgg atcttcgtga agaagatttt acagcattag aagctgcaaa agacttgaat
    16681 gatttcctag gaatcaacta ctatatgagt gactggatgg aagcctttga tggagaaact
    16741 gaaattatcc ataatggtaa aggtgaaaaa ggaagctcta agtatcaaat caaaggtatt
    16801 ggtcgtcgtg tagctcctga ctatgtatca cgcacggatt gggattggat tatctaccct
    16861 caaggtttgt atgaccaaat catgcgtgtg aagaaagatt atcctaacta caagaagatt
    16921 tacatcactg aaaatggtct cggctataaa gatgagttcg ttgataacac tgtttacgat
    16981 gatggtcgta ttgattacgt gaaacaacac ttggagatct tgtctgatgc gattgcagat
    17041 ggagctaatg taaaaggtta cttcatttgg tcattaatgg atgtcttctc atggtcaaac
    17101 ggttatgaga aacgttatgg tctcttctac gtagattttg aaactcaaga acgttatcct
    17161 aagaaatcag ctcactggta caagaaagta gcggaaactc agattataga ctagtagaat
    17221 tagtcattag atatagaatt ttagtgagtc aaaaagatgt tcaaagattt tatccaatct
    17281 atttatgaaa aaaagtttat attataaatt tcgaaaaatg ctctcaaata ccgtgtttga
    17341 cgagtgaaga attgaaaagt cttggaaaat ggtatgtctc gactggtaaa gaatggattt
    17401 gtcattcaga tgatgagctg gaagaattta aaaatctatt tttaaatttt atcaatcctg
    17461 aagaatggga tactatctcc tttgattcag attttatgcc gtttcaacaa tcgtaaccaa
    17521 tttctcaaaa aagttaaatc ttatatttag tactctgtaa aactcttatc taatcacgtt
    17581 gcttatactc aatgaaaatc aaagagcaac tttaaactag gaagcgagtc gcagatttct
    17641 caatgcatag ctttgaggaa ttgggcaaaa agtctttgat atagaaaaaa gcatagtatc
    17701 aggtgttgaa acacctgata ctatgctttt tattgtggga agatttactt tttttcttct
    17761 gaaattgagt tgttacccag gctctttcag tttattaagg cttgatgact ttaatgtgtt
    17821 tagatagctt aaaaaggatt gaatcactta gtttagaatc tgaaacaata gtatcaagat
    17881 ttgatatatt ataaaaagta taaaaatcaa acttattgaa cttactatga tctgcgagta
    17941 aatatttttt attagaatta tttaaagcga tgcgttgagc ctctccctct tcctcgctaa
    18001 aagtagctag agctccgttt tgaataccat tacagctaac gaaagcttta gaaaattgga
    18061 gattagagag attttgtagg gtcaatgtgc caacaaaagc acctgtaata tcgcgataat
    18121 ttccacctat caaaatcaaa tctgttaatt ttcgttcgct taaaatcaga aaaacaggta
    18181 gactgttggt tacgacgcgg atattgtcaa taggcaactc acgcgcaaaa aactctaatg
    18241 ttgttcctgg tccaatgaaa atagtttctc tttcttctac tagactgcct gcaaaatggg
    18301 ctatttcttg tttttctgcc gtttggaggg cttgtttttc aatatttgat cgctcattag
    18361 tcaaaaggga gttggttcga agtttttcag ctccaccatg cacacgaatc agcaaatctt
    18421 tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc tgaaacggct atttcgtcca
    18481 taatctgttt aactgttatg gttcctttac tatttactat ctctaaaatt ttggttaatt
    18541 tttcttgttt gagcatatta tcacctcgtt tcctactact atcttaccat aaacaaactc
    18601 atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa aaatatcgaa gtttgttttc
    18661 aaaactttcg atatttttgt tgggttatta ttttgttgtt tctagtttac tttttgatgg
    18721 ttaagagtgg tggagaatta tactcaatga aaatcaaaga gcaaactagg aagctagccg
    18781 caggctgtac ttgagtacgg caaggcgaag ctgacgtggt ttgaatttga ttttcgaaga
    18841 gtattagtcc aaaccgtagt tgtagtcatc atcttgcatg gcttcaactt cgccaagaag
    18901 gtaaccattt ccgacttgag agaagaagtc atggttggaa gttcctgttg aaataccgtt
    18961 cataacgatt gggttgacat cttcagctga atctgggaaa agtggatctt gtcccatgtt
    19021 catgagagct ttattggcat tgtagcgaag gaaggtttta acctcttcag tccaaccaac
    19081 accgtcataa agactctctg tgtagccttc ttcattttca taaagagtat agagtaggtc
    19141 gtacatccat tctttgagtt tttcttgctc ttcttcaggc aattcattga aaccaagttg
    19201 gaatttgtaa ccaatgtagg ttccgtgaac agactcgtca cgaataatca atttaatgat
    19261 ttctgcaacg ttggctagtt tgttgttacc gagatagtag aggggagtga agaaaccaga
    19321 gtagaagagg aaggtttcga ggaagacgct ggcaactttc ttttcaagtg ggctgccgtt
    19381 taggtagatt tcgttgacaa tctcagcctt cttttgtagg taaggattgg tattggtcca
    19441 ttcgaaaatt tcttcaatct cagccttagt attcaaggta gaaaagattg atgagtaaga
    19501 tttagcgtgg acagattcca taaattggat gttattgaaa acagcttcct catgtggtgt
    19561 acggatgtct gcgcgaaggg cttgaacccc agtttcagat tgcatagtgt caagaagggt
    19621 taaaccacca aaaacttttc caactaagtc tttttctttg ttagatagct ttctccagtc
    19681 atccaagtcg tttgacaagg gaatacgtgt atcgagccag aattgctccg tcagtttttc
    19741 ccaagttgat ttatcgatga catcttcgat ggcattccag ttaatggctt tgtagtaagt
    19801 ttccatttga aatctctttc tgtgtttagt attgcgaact cacaattatg tctatttcac
    19861 cataattcta taggagtatc gcacaaaaag tcggaagccc gacttttaaa atgttacata
    19921 aattatgtta tgacctagta gatttgattt tatcagtgct gcttagggaa aaatagtgtt
    19981 tctatgctag aaactaaatc acacagcttt cacattggtt agcaccgact tctccaccat
    20041 catctgtaaa ggtacggacg tagtagatag acttgatacc cttgttaaag gcgtagttgc
    20101 gaaggataga caagtcacgt gtcgtttgtt tattttcctt cttccattcg taaaggcctt
    20161 ttggaatgtc actacgcata aagagtgtga gtgaaagtcc ttggtccacg tgctctgttg
    20221 cagcggcgta aacatcaatc actttacgca tatccatgtc gtaagccgaa gtgtagtaag
    20281 gaatggtttc tgttgacaag ccagcagcag gatagtagat tttaccaatt ttcttttctt
    20341 gacgttcctc gatccgttgc gtaatcgggt ggatagaagc agaaacgtcg ttgatgtaac
    20401 tgatcgaacc atttggagca acagctagac ggttttggtg gtaaagacca tctgcttgaa
    20461 tcttgtcgcg aagttcagcc caatcagcag cactagggat aaagacatct ttgaagagtt
    20521 ctttaacacg gtctgatttt ggaacaaatt cgccagttac atacttgtcg aagtagcttc
    20581 ccttagcata gtctgatttt tcaaagttat ggaaggtaat accacgttca cgcgcaatat
    20641 tgtttgactc aaccaaagtc cagtagttca taagcataaa gtagatgctt gtaaagtcaa
    20701 cagactcagg tgatccatat tcaatcaatt gttgggcaag gtagctgtga agtcccatgg
    20761 cgccaagacc aaaggtgtga gcttggctat ttccatggtc aatcgtaggg acagctacga
    20821 tgtgtgaact atctgtaacg aaagttaaag cacgaaccat agcacggata gaacgaccaa
    20881 agtcaggtga agtcatcatg ttgactacgt tggttgaacc aaggttacat gaaacgtccg
    20941 ttcccatttg aaggaattct tgagcatcgt tgatcaagct tggttcttgg acttgaagaa
    21001 tctcagaaca caagttactc atgataatct taccatcaac aggatttgca cggttagccg
    21061 tatcaatgtt gacgacataa gggtagccag attcttgttg caatttagag atttcagttt
    21121 ccaaatcacg cgccttgatt tttgtcttgc ggatatttgg atttgcgact aattcatcgt
    21181 atttttcagt gatgtcaatg tagttgaatg gcacaccgta ttcaagctct acagagtaag
    21241 ggctgaagag gtacatttct tcatttttac gagccaattc gtagaattta tctggtacta
    21301 caacaccaag tgaaagggtc ttgacacgaa ctttttcatc ggcgttttct ttcttagttg
    21361 aaaggaaggc gatgatatct ggatgaaaga cattgaggta aaccacccca gcaccttgac
    21421 gttgccccaa ttggttggag taagagaaac tgtcttcgaa gagtttcata actggaacga
    21481 ctccagaagc tgctccttca tagcctttga taggtgcacc agcttcacga aggttgctga
    21541 gggtaattcc cacaccacca ccgatacgtg aaagttgaag agctgagttg atagaacgtc
    21601 cgatagagtt catatcatcc gtcacttgga ttaggaaaca agataccaac tccccacgac
    21661 gagcacgtcc agcattcaag aaggaaggag tagcaggttg gtagcgttgg tggatgattt
    21721 cattggcaat atcgattgca acagattcat tgccatcagc gaaataaagg gcgttaaaga
    21781 agacacggtc ttccatactt tcaagataat attcaccgtc gttagtcttt aaggcatatt
    21841 gattgtaaaa tttataagct gccatgaaag acttgaattg gaagttttgg tctttgataa
    21901 attgtgacaa ttcttccaag aactctggac ggtatttctt gataaaggct gtttcgatgt
    21961 agttgtggtc aatgaggtag ttgattttat ctttaattga atcaaaaacc atagtgtttg
    22021 gaacgacatt ttctttaaag aaggcatcca aggcttcctt atctttatga agcatgattt
    22081 gtccattgac aggacggttg atttcgttat tgagacggaa gtaagtcacg tcttcaagat
    22141 gttttaatcc cataaaattt cccttatcta attacaaaag aaaggcttct aagctagccc
    22201 tagaagcagt ttcttctgga tgatgtacta agattatgct aattgtttca gttttcctgg
    22261 ttggaaacct gaaaagactt cagttggtgt ttggataata ggagctgcgc taaaaccgag
    22321 ttctttgact tgatcgatgt actcaggctg ctcatcaaga ttgatttctt tatattcaac
    22381 gttattactg tccaagaaac gcttggtcat tttacattgg acacaattgt ttttagaata
    22441 aacggttacc attgtgtaac tcctcttcaa aatttaatac tatcttagta tatcagaaaa
    22501 taaaaatttg tcaatgattt aaactaaata tagtggtcta tttttctagt caagctcaca
    22561 aaacacaata tgtagtgttt ggtttataaa atagcaatga ttatcctata aatcgttttt
    22621 aaagaaacta tatcctgtgt tttgttatct aggacagaag attttcagca agttatctga
    22681 aaggaaattg aaggaaaatc cagaaaatgc ttgaaaaaaa tcctagaaga tgatataata
    22741 ccaaattgta agggttatca catataactc aaaaaagaaa gaacaaaagg agagtcaaac
    22801 tatggcttct aaagatttcc acgtagtggc agaaacaggt attcacgcac gtccagcaac
    22861 attgttggtg caaactgcta gcaaatttgc ttcagatatc actcttgagt acaaaggtaa
    22921 atcagttaac cttaaatcaa ttatgggtgt tatgagtctt ggtgttggcc aaggtgctga
    22981 cgtaactatc tcagctgaag gtgcagatgc agatgacgct atcgctgcaa tctcagaaac
    23041 aatggaaaaa gaaggattgg cataagggaa atgacagaaa tgcttaaagg aatcgcagca
    23101 tctgacggtg ttgcagttgc aaaagcatat ctactcgttc aaccggattt gtcattcgag
    23161 actatttcag tcgaagatac aaacgcagaa gaggctcgtt tggatgttgc tcttgaagct
    23221 tctcaaaacg agctttctct tatccgcgag aaagctgtag gtacgcttgg tgaagaagcg
    23281 gctcaagttt ttgacgctca tttgatggtt ctttctgacc cagaattgat tggtcagatt
    23341 aaagaaacaa ttcgtgctaa gaaagtcaat gcagaagcag gtcttaaaga agtgactgat
    23401 atgttcatca ctatctttga aggcatggaa gacaacccat acatgcaaga acgtgcagcg
    23461 gatatccgag acgtgacaaa acgtgtattg gcaaaccttc ttggtaagaa attgccaaac
    23521 ccagcttcta tcaatgaaga agtaatcgtg attgcgcatg acttgacacc atctgataca
    23581 gctcaattgg acaaaaactt tgtaaaagct tttgtaacaa acatcggtgg acgtacaagc
    23641 cactcagcta tcatggcacg tacacttgaa attgcagctg tattgggaac aaataacatc
    23701 actgaagtgg tgaaagacgg tgatatcctt gccgttaacg gaattactgg tgaagtgatt
    23761 atcaacccaa cagatgaaca agcggcagaa tttaaagcag ctggtgaagc ttatgctaaa
    23821 caaaaagctg aatgggcact tttgaaagat gctcaaacag tgactgctga cggtaaacac
    23881 ttcgagttgg ctgctaacat cggtactcca aaagacgttg aaggtgttaa caacaacggt
    23941 gcagaagctg ttggacttta ccgtacagag ttcttgtaca tggattctca agacttccca
    24001 actgaagatg agcagtatga agcatacaag gctgttcttg agggaatgaa tggtaaacca
    24061 gtggttgttc gtacaatgga tatcggtgga gataaggaac ttccttactt tgatatgcca
    24121 catgaaatga acccattcct tggtttccgt gctcttcgta tctctatttc tgaaactgga
    24181 gatgcaatgt tccgtacaca aatccgtgcc cttcttcgtg cttctgttca tggtcaattg
    24241 cgtatcatgt tcccaatggt tgccctattg aaagaattcc gtgcagctaa agcagtcttt
    24301 gacgaagaaa aagcaaacct tcttgcagaa ggagttgcag ttgcggatga tatccaagtt
    24361 ggtatcatga ttgaaatccc tgcagcagcg atgcttgcag accaatttgc taaagaagta
    24421 gacttcttct caattggtac aaacgacttg atccaatata caatggcagc agaccgtatg
    24481 aatgagcaag tttcatacct ttaccaacca tataacccat caatcctacg cttgattaac
    24541 aatgtgatca aagcagctca cgctgaaggt aaatgggctg gtatgtgtgg tgagatggct
    24601 ggtgaccaac aagctgttcc acttcttgtc ggaatgggct tggatgagtt ctctatgtca
    24661 gcaacatctg tacttcgtac acgcagcttg atgaagaaac tcgacacagc taagatggaa
    24721 gagtacgcaa accgtgccct tacagaatgc tcaacaatgg aagaagttct tgaacttcaa
    24781 aaagaatacg ttaattttga ttaatcgaaa agtccctgca actcagttac agggactttt
    24841 tttgatattt taaaaagaat tttcaagaaa atctttctta taaaaagtcc aaccttgaaa
    24901 aagtagtggt cagaacaaaa aatacttaaa tggttcataa aattcttgac aagttggaga
    24961 tttaggagta aactattaac cagttaagta atagagagga gtttctgcaa tttagaaatg
    25021 aattgcaact agaaatatca aatagaaaga gagtttcgat gaaaattaat aagaaatacc
    25081 ttgttggttc tgcggcagct ttgattttaa gtgtttgttc ttacgagttg ggactgtatc
    25141 aagctagaac ggttaaggaa aataatcgtg tttcctatat agatggaaaa caagcgacgc
    25201 aaaaaacgga gaatttgact cctgatgagg ttagcaagcg tgaaggaatc aatgctgagc
    25261 aaatcgtcat caagataaca gaccaaggct atgtcacttc acatggcgac cactatcatt
    25321 attacaatgg taaggttcct tatgatgcga ttttcagtga agaattactc atgaaagatc
    25381 caaactataa gctaaaagat gaggatattg ttaatgaggt caagggtgga tatgttatca
    25441 aggtagatgg aaaatactat gtttacctta aggatgctgc ccacgcggat aacgtccgta
    25501 caaaagagga aatcaatcga caaaaacaag aacatagtca acatcgtgaa ggtgggactc
    25561 caagaaacga tggtgctgtt gccttggcac gttcgcaagg acgctatact acagatgatg
    25621 gttatatctt taatgcttct gatatcatag aggatactgg tgatgcttat atcgttcctc
    25681 atggagatca ttaccattac attcctaaga atgagttatc agctagcgag ttggctgctg
    25741 cagaagcctt cctatctggt cggggaaatc tgtcaaattc aagaacctat cgccgacaaa
    25801 atagcgataa cacttcaaga acaaactggg taccttctgt aagcaatcca ggaactacaa
    25861 atactaacac aagcaacaac agcaacacta acagtcaagc aagtcaaagt aatgacattg
    25921 atagtctctt gaaacagctc tacaaactgc ctttgagtca acgacatgta gaatctgatg
    25981 gccttgtttt cgacccagcg caaatcacaa gtcgaacagc tagaggtgtt gcagtgccac
    26041 acggagatca ttaccacttc atcccttact ctcaaatgtc tgaattggaa gaacgaatcg
    26101 ctcgtattat tccccttcgt tatcgttcaa accattgggt accagattca aggccagaac
    26161 aaccaagtcc acaaccgact ccggaaccta gtccaggccc gcaacctgca ccaaatctta
    26221 aaatagactc aaattcttct ttggttagtc agctggtacg aaaagttggg gaaggatatg
    26281 tattcgaaga aaagggcatc tctcgttatg tctttgcgaa agatttacca tctgaaactg
    26341 ttaaaaatct tgaaagtaag ttatcaaaac aagagagtgt ttcacacact ttaactgcta
    26401 aaaaagaaaa tgttgctcct cgtgaccaag aattttatga taaagcatat aatctgttaa
    26461 ctgaggctca taaagccttg tttgaaaata agggtcgtaa ttctgatttc caagccttag
    26521 acaaattatt agaacgcttg aatgatgaat cgactaataa agaaaaattg gtagatgatt
    26581 tattggcatt cctagcacca attacccatc cagagcgact tggcaagcca aattctcaaa
    26641 ttgagtatac tgaagacgaa gttcgtattg ctcaattagc tgataagtat acaacgtcag
    26701 atggttacat ttttgatgaa catgatataa tcagtgatga aggagatgca tatgtaacgc
    26761 ctcatatggg ccatagtcac tggattggaa aagatagcct ttctgataag gaaaaagttg
    26821 cagctcaagc ctatactaaa gaaaaaggta tcctacctcc atctccagac gcagatgtta
    26881 aagcaaatcc aactggagat agtgcagcag ctatttacaa tcgtgtgaaa ggggaaaaac
    26941 gaattccact cgttcgactt ccatatatgg ttgagcatac agttgaggtt aaaaacggta
    27001 atttgattat tcctcataag gatcattacc ataatattaa atttgcttgg tttgatgatc
    27061 acacatacaa agctccaaat ggctatacct tggaagattt gtttgcgacg attaagtact
    27121 acgtagaaca ccctgacgaa cgtccacatt ctaatgatgg atggggcaat gccagtgagc
    27181 atgtgttagg caagaaagac cacagtgaag atccaaataa gaacttcaaa gcggatgaag
    27241 agccagtaga ggaaacacct gctgagccag aagtccctca agtagagact gaaaaagtag
    27301 aagcccaact caaagaagca gaagttttgc ttgcgaaagt aacggattct agtctgaaag
    27361 ccaatgcaac agaaactcta gctggtttac gaaataattt gactcttcaa attatggata
    27421 acaatagtat catggcagaa gcagaaaaat tacttgcgtt gttaaaagga agtaatcctt
    27481 catctgtaag taaggaaaaa ataaactaat gaaaaatgaa agtctcgata aagaggcttt
    27541 catttttatt atgtatatat gtaaaattct tgacaagcaa tattaaaaag agtaaactat
    27601 taactagtta attaaccggt ttattacttt atagtgaatc aaatatactt aagaaaagag
    27661 gaaagaatga aaatcaataa aaaatatcta gctgggtcag tagctacact tgttttaagt
    27721 gtctgtgctt atgaactagg tttgcatcaa gctcaaactg taaaagaaaa taatcgtgtt
    27781 tcctatatag atggaaaaca agcgacgcaa aaaacggaga atttgactcc tgatgaggtt
    27841 agcaagcgtg aaggaatcaa tgccgaacaa atcgtcatca agataacaga ccaaggctat
    27901 gtcacttcac atggggacca ctatcattat tacaatggta aggttcctta tgacgctatc
    27961 atcagtgaag aattgctgat gaaggatcca aactaccagc taaaggacga ggatattatc
    28021 agtgaaatca agggtggtta tgtgattaag gtagatggaa aatactatgt ttaccttaag
    28081 gatgcagctc atgcggataa tgtccgtaca aaagaagaaa tcaatcggca aaaacaagaa
    28141 catagtcagc atcgtgaagg agggacttca acaaacgatg gtgcggtagc ctttgcacgt
    28201 tcacaaggac gctatactac agatgatggt tatatcttta atgcttctga tatcattgag
    28261 gacacgggtg atgcttatat cgttcctcac ggcgaccatt accattacat tcctaagaat
    28321 gagttatcag ctagcgagtt agctgctgca gaagccttcc tatctggtcg gggaaatctg
    28381 tcaaattcaa gaacctatcg ccgacaaaat agcgataaca cttcaagaac aaactggcta
    28441 ccttctgtaa gcaatccagg aactacaaat actaacacaa gcaacaacag caacactaac
    28501 agtcaagcaa gtcaaagtaa tgacattgat agtctcttga aacagctcta caaactgcct
    28561 ttgagtcaac gccatgtaga atctgatggc cttgttttcg acccagcgca aatcacaagt
    28621 cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat cccttatgaa
    28681 caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta tcgttcaaac
    28741 cattgggtac cagattcaag accagaacaa ccaagtccac aatcgactcc ggaacctagt
    28801 ccaagtctgc aacctgcacc aaatcctcaa ccagctccaa gcaatccaat tgatgagaaa
    28861 ttggtcaaag aagctgttcg aaaagtaggc gatggttatg tctttgagga gaatggagtt
    28921 tctcgttata tcccagccaa ggatctttca gcagaaacag cagcaggcat tgatagcaaa
    28981 ctggccaagc aggaaagttt atcgcataag ctaggagcta agaaaactga cctcccatct
    29041 agtgatagag aattttacaa taagacttat gacttactag caagaattca ccaagattta
    29101 cttgataata aaggtcgaca agttgatttt gagg
//
LOCUS       DAVKBK010000023        26381 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVKBK010000023 DAVKBK010000000
VERSION     DAVKBK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.023"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            584..2737
                     /locus_tag="VWX69_001104"
     CDS             584..2737
                     /locus_tag="VWX69_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU9192460.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKANMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2750..4099
                     /locus_tag="VWX69_001105"
     CDS             2750..4099
                     /locus_tag="VWX69_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU9192461.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4269..4976
                     /locus_tag="VWX69_001106"
     CDS             4269..4976
                     /locus_tag="VWX69_001106"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU9192462.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            5033..8758
                     /locus_tag="VWX69_001107"
     CDS             5033..8758
                     /locus_tag="VWX69_001107"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU9192463.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            8851..10293
                     /locus_tag="VWX69_001108"
     CDS             8851..10293
                     /locus_tag="VWX69_001108"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU9192464.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10330..11352
                     /locus_tag="VWX69_001109"
     CDS             10330..11352
                     /locus_tag="VWX69_001109"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU9192465.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11349..11894
                     /gene="purN"
                     /locus_tag="VWX69_001110"
     CDS             11349..11894
                     /gene="purN"
                     /locus_tag="VWX69_001110"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU9192466.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            11978..12487
                     /locus_tag="VWX69_001111"
     CDS             11978..12487
                     /locus_tag="VWX69_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9192467.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12512..14059
                     /gene="purH"
                     /locus_tag="VWX69_001112"
     CDS             12512..14059
                     /gene="purH"
                     /locus_tag="VWX69_001112"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU9192468.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQEFIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14181..15443
                     /gene="purD"
                     /locus_tag="VWX69_001113"
     CDS             14181..15443
                     /gene="purD"
                     /locus_tag="VWX69_001113"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU9192469.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            15836..16324
                     /gene="purE"
                     /locus_tag="VWX69_001114"
     CDS             15836..16324
                     /gene="purE"
                     /locus_tag="VWX69_001114"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU9192470.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16311..17384
                     /gene="purK"
                     /locus_tag="VWX69_001115"
     CDS             16311..17384
                     /gene="purK"
                     /locus_tag="VWX69_001115"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU9192471.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVGEF"
     gene            17407..19794
                     /locus_tag="VWX69_001116"
     CDS             17407..19794
                     /locus_tag="VWX69_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9192472.1"
                     /translation="MFEKIKGINIKSGIFEDETKLELFEGNFEGTNPVQNDRASLLFG
                     RNGSGKSTIARGINQLKNGEIGTDRVSFIDKNNNNIVLSDTERKSIFVFNEHYVDQKV
                     KIAQEGLDTIVILGEQVDIDEELDRLRTQLSESQIESQDYYAEYEEYLDEKNEKSPDF
                     WKKEMTDSLKGVGNWAERDREIKGNRAASPVHNNTFQNFVDLQPILDKNELEVEFNNK
                     KARYFSIRDSAVTINNELSLPDINFDSNELSTLLSEKIEEPELNSRDKYLLTLLSDST
                     KGERHLREVKDFFEDEHQKKCPFCTQSVSEDVKVELTNGITKLLSRAVEEHQSALRGK
                     KIDEINQDFSGYEQIDPILIQSYQNSINALNAKFNEINSIIDKKIDNPYNIVELPNIS
                     FSQELSQAEHDIEKINQAIIKHNSEISGIQKLKVDLLQINNELAFYEIQDAYKKFQEK
                     TNKKAICENNYNNSSKRVKDYEKQISDLEDKKLNIDIAVDEINKSLNYIFFSKNRLAI
                     QNQNGKYYLLSRGKSVVPSRVSVGERNALALCYFFTEIIQQRELADAYSHEYFIVIDD
                     PISSFDMENKVGITSYLKYCLTRFFKGNSNTRVLLMTHDKQTIYDFDIFLKEIMESCK
                     EEEGGQKSKYKKLELVSGKLQEFKTSTHDYTELLEIVFGYALGNSTPTSESFVGNAMR
                     KILEAYGSFNYKKGIAELTTDPLIVEKIDKEYRTYFENLMYRLVLNGESHFKDPVKTL
                     SIDFFDTISDEERKKTARDLLVLLYLLDDLHVLKHLEGVSNAENRLEQWKCEILE"
     gene            19967..21265
                     /gene="purB"
                     /locus_tag="VWX69_001117"
     CDS             19967..21265
                     /gene="purB"
                     /locus_tag="VWX69_001117"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU9192473.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEINEIFNPIYYTKRVDDIFERLGLGD"
     gene            complement(21320..25258)
                     /gene="strH"
                     /locus_tag="VWX69_001118"
     CDS             complement(21320..25258)
                     /gene="strH"
                     /locus_tag="VWX69_001118"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9192474.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPRLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(25573..26289)
                     /locus_tag="VWX69_001119"
     CDS             complement(25573..26289)
                     /locus_tag="VWX69_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9192475.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
BASE COUNT         7481 a         5029 c         6100 g         7771 t
ORIGIN      
        1 tctaaaaata taaccttaag ttttagcatt ttactttgtt atttatttaa tccatcggat
       61 ataaagtttg cctatttcag cgtattgaca gtattactaa ttgggataac aaattatgcg
      121 agatttaaaa atttaagatt gacagtagtg ttttctgtac catttttatt taatgctata
      181 atgtctatta taaatagttt ttagaaatac taaaattttt ttctttactt aataatgata
      241 tgaaatcatt tcggttttgt taacttgtaa ttcttatatt ttctaggtag aacgtttgtt
      301 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
      361 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
      421 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
      481 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
      541 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
      601 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
      661 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
      721 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
      781 agccattaag gcgaatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
      841 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
      901 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
      961 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     1021 tcataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     1081 cttgattgcc aatatcgttt tggcaacact cttggtaacc gtgattaaca ttgtgggttc
     1141 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     1201 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     1261 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     1321 caagcatgtt tttcacctcc ctatgtcctt ctttgcgaca cgcaggacag gggagatcgt
     1381 gtctcgtttt acagatgcta acagtatcat cgatgcgctg gcttcgacca tcctttcgat
     1441 tttcctagat gtgtcaacgg ttgtcattat ttcccttgtt ctattttcac aaaataccaa
     1501 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     1561 gaagccgttt gaaaagatga atcgggatac catggaagcc aatgcggttc tgtcttcttc
     1621 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     1681 ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     1741 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttgctta atgtcggcat
     1801 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     1861 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     1921 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     1981 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag atatgacctt
     2041 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     2101 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     2161 ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     2221 caatctcaat cagattgata aaaaagccct gcgccagtac atcaactatc tgcctcaaca
     2281 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     2341 gacacaggaa gatatcttac gggcggtcga attggcagag attcgagagg atatcgagcg
     2401 catgccactg aattatcaga cagaattgac ttcggatggg gcagggattt caggtggtca
     2461 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     2521 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcattgc
     2581 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     2641 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     2701 acagggaggc ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     2761 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     2821 tgtacccatg gcccttttgc tcgtgttttt acttggcttt gcaactgttg cagagaagga
     2881 gatgagtttg tccactagag ctactgtcga acccagtcgt atccttgcaa atatccagtc
     2941 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     3001 ggatcttttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     3061 tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa agagcctgca
     3121 agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca cctttcgcga
     3181 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     3241 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     3301 agaggctaaa attcgcgatt accagacagc taagtcagct attgaaacag gtacttcctt
     3361 ggccggtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     3421 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     3481 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     3541 agggttaagc agtcaattgg aatcccttaa atcccaacac ttggcaaagg ttggtcagga
     3601 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     3661 tcttttagac aaggggaaaa ttacggcaag tgaggatggg gtgcttcatc ttaatcctga
     3721 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     3781 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     3841 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aactttttct
     3901 agattctact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     3961 taaaatcgag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     4021 ggaaggccgt ctacagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     4081 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     4141 aagattcttc ttgcagtttt ttctttacaa tttttgaaaa acatctgcta tttattcggt
     4201 taaattcttg tgttttttgg ttttttgtgg taaaatgtgc tcaagtaata cgaaaggcga
     4261 actttaaaat gtcaaaacaa ttgatctatt cgggaaaagc taaagatatc tatacaactg
     4321 aggatgaaaa tcttattatt tcaacttaca aggaccaggc gactgctttc aatggtgtca
     4381 agaaggagca gattgcaggt aagggagtct tgaataatca gatttcatct tttatttttg
     4441 agaaattaaa tgcggctggt gtggcgactc actttgtgga gaaactttca gacacggaac
     4501 aactcaataa aaaggttaag attattcctt tggaagtcgt gctccgcaac tatactgctg
     4561 gttccttttc aaaacgtttt ggtgtggatg agggaatcgc cttggagact ccgattgtcg
     4621 aattttacta caaaaatgat gatttggatg atccatttat caatgatgag catgtaaaat
     4681 tcctacagat tgcggatgac cagcagattg cctacttgaa ggaagaaacg cgtcgtatca
     4741 atgaactatt gaaagtctgg tttgctgaga ttgggcttaa attgattgac tttaagctag
     4801 agttcggttt tgacaaggat ggcaagatta tcttggcaga cgaattttca ccagataact
     4861 gccgcttgtg ggatgctgat ggcaaccaca tggataagga tgttttccgt agaggattgg
     4921 gagaactaac cgacgtttat gagattgttt gggaaaagtt gcagggttta aaataacaac
     4981 ctcaaggctg tttgggaata ttgcaagagc tgaaataaag gaataagaat tgatggataa
     5041 acgtattttt gttgaaaaaa aggctgattt tcaggtcaag tcagagagtt tggttagaga
     5101 gctccagcac aacttgggac tgtcaagctt gaaaagtatt cgtattgtgc aagtatatga
     5161 tgtatttgac ttggttgagg acttgtttgc acctgcagag aagcacattt tctctgagca
     5221 ggtaaccgac catgttttag atgaagtatc tgtgcaggcg gatcttgcta actatgcttt
     5281 ctttgccatt gaaagtctac cagggcagtt tgaccagcgt gcagcttcgt cacaggaagc
     5341 cttgcttttg ttgggaagtt cgagtgacgt gacagtcaac acagcccaac tttacttggt
     5401 gaataaagat attgatgcga ctgagttgga agctgtcaaa aactacctgc tcaatccagt
     5461 tgattctcgt ttcaaggata tcacgatagg gattgccaag caggagtttt cagagtcaga
     5521 caagaccatt ccaaaattgc ctttctttga aagctataca gcagaagact ttgctcgcta
     5581 caaggccgaa caagggatgg ccatggaagt ggatgatttg ctctttatcc aagactactt
     5641 taagtcaatc gggcgcgtgc caactgagac tgaactcaag gttttggaca cttactggtc
     5701 tgaccactgc cgtcatacga cttttgagac agagttgaaa cacatcgact tttcagcttc
     5761 taaatttcaa aagcaattgc agtcaaccta tgacaagtat attgccatgc gcgaggaatt
     5821 aggtcggtct gaaaaaccac aaaccttgat ggatatggcg actattttcg gtcgttatga
     5881 gcgtgctaat ggacgattgg atgatatgga agtctctgac gaaatcaatg cctgctcagt
     5941 tgaaattgaa gtggacgttg atggtgtcaa ggaaccttgg ctcctcatgt ttaaaaacga
     6001 aactcacaac catccaacag aaattgagcc atttggtgga gcggctacct gtatcggtgg
     6061 agctattcgt gatccgttgt caggccgttc ctatgtttac caagccatgc gtatttcagg
     6121 tgctggtgat attacagcac cgatttcgga aactcgtgct gggaaattgc cacaacaagt
     6181 catttctaaa acagcaactc atggttattc ttcatatggt aaccagattg ggcttgccac
     6241 aacctacgtt cgtgaatact tccacccagg ctttgtagct aaacgtatgg aacttggtgc
     6301 cgttgttggt gcggctccca agggcaatgt tgtccgtgaa aaacctgaag caggtgatgt
     6361 gatcatcctt ctcggaggta aaacaggtcg tgatggtgtc ggtggtgcga cgggctcttc
     6421 taaggttcaa acagttgagt ctgtagagac tgctggtgct gaggttcaaa aaggaaatgc
     6481 catcgaagaa cgcaagattc agcgcctctt ccgtaatggc aatgtcactc gtctgatcaa
     6541 gaagtccaat gactttgggg caggcggtgt ctgtgtggct atcggtgaat tggcagacgg
     6601 tcttgaaatc gacctcaaca aggtgcctct taaataccag ggcttgaatg gtacagaaat
     6661 tgccatctct gaatcacaag aacggatggc ggtcgtggtt cgtcctgaag atgtggatac
     6721 cttcgttgcc gaatgtaaca aagaaaatat tgatgctgtt gtggtggcga cagtaactga
     6781 aaaaccaaat cttgtcatgc actggaatgg tgagacaatc gttgacttgg agcgtcgttt
     6841 ccttgacatc aatggtgtgc gcgtggttgt cgatgccaaa gttgtggaca aggatgtcaa
     6901 actcccagaa gagcgtcaaa catctgctga aacactggaa tcagataccc ttacggttct
     6961 atctgacctc aaccatgcaa gtcaaaaagg attacagact atctttgact gctctgttgg
     7021 acgctcaacg gttaatcacc cacttggtgg tcgttaccaa ctcacaccaa ctgaggcatc
     7081 tgtgcagaaa ttgccagttc aacacggtgt gactcatact gcgtcggtca ttgctcaagg
     7141 tttcaaccca tatgtagctg aatggtctcc ataccacggt gctgcttatg cggttatcga
     7201 agcaactgct cgtttggtgg ctgctggtgc caactggtcc aaggctcgtt tctcttacca
     7261 agaatatttc gagcgtatgg acaagcaagc agagcgtttt ggtcagccag tagccgctct
     7321 tctaggctct attgaagctc agattcaact tggcttgcca tctatcggtg gtaaggactc
     7381 catgtctggt acctttgaag aattgaccgt tccgccaacc ttggttgcct ttggggtgac
     7441 gacggcagat agccgtaagg tgctctctcc agaatttaaa gctgttgggg aaaatatcta
     7501 ctacatccca ggtcaagccc tctctgcaga gattgatttt gacttgatta agaaaaattt
     7561 tgctcagttt gaagcaagcc aagctgacca taaagtgaca tctgcatcag ctgtcaaata
     7621 cggtggtgta gttgaaagtt tggctcttgc tacctttgga aactatattg gtgcagaggt
     7681 gaccttgcct gaacttaaaa cagctttgac agctcaatta ggcggctttg tcttcacatc
     7741 tcctgaagaa attgctggag tagagaagat tggacaaacg aaagcagact ttacactgac
     7801 tgtcaacggt gtgaagctag atggacacaa gcttgacagt gcatttcaag ggacattgga
     7861 agaagtttac ccaacagaat ttacccaagc gaaagaacta gaagaagtac cagctgtggc
     7921 atcagatgtt gtgattaaag ccaaagaaaa ggttgaaaaa cctgtggttt acatcccagt
     7981 ctttccagga accaactcag aatatgattc agctaaggcc ttcgaaaaag aaggtgcaga
     8041 ggtcaatttg gtgccattcg tgaccttgaa tgaagaagct attgtcaagt cagttgaaac
     8101 tatggttgac aatatcgaca agactaatat tctcttcttt gctggtggat tctcggctgc
     8161 ggatgaacca gatggttcag ctaagtttat cgtcaatatc ctgcttaatg aaaaagtgcg
     8221 tgtggctatt gatagcttta tcgcccgtgg tggtttgatt atcggtattt gtaatggatt
     8281 ccaagcctta gtcaaatcgg gtctcctacc ctacggaaac tttgaagatg ctaacaatac
     8341 tagcccaacc ctcttctaca atgatgccaa ccaacacgtg gccaagatgg tggaaactcg
     8401 cattgccaat accaactcac catggttggc tggtgtgcaa gtgggcgata tccacgctat
     8461 tcctgtttcg cacggtgaag ggaagtttgt cgtgacggct gaggaatttg cagagctccg
     8521 tgacaatgga caaattttca gccaatacgt tgactttaac ggtaaaccaa gtatggattc
     8581 taagtacaat ccgaatggtt ctgtccatgc catcgaagga attaccagca agaatggtca
     8641 aatcatcggt aagatgggcc actcagaacg ttatgaggat ggtcttttcc aaaatatccc
     8701 aggcaataaa gaccaacacc tgttcgcatc agcggttaaa catttcactg gaaaataaga
     8761 cttacagatt ttctaataga tagtatcagt aatgtaaaag tcatgtaaat ctagctcttg
     8821 atgattacaa atgaaaatta ggtataaaaa atgacatacg aagtaaaatc tcttaatgaa
     8881 gaatgtggtg ttttcggtat ttggggacat ccagatgctg ctaagttgac ctattttgga
     8941 ctccacagtc ttcaacaccg tggtcaggag ggggcaggaa tcctctccaa tgatcaagga
     9001 caactgaagc gccatcgtga catggggctt ttatcagaag ttttcagaaa tccagccaat
     9061 ttggataaat tgacaggagc tggtgcgatt gggcatgtgc gttatgcgac tgctggcgaa
     9121 gcttctgttg ataacatcca gcccttcctc ttccgttttc acgatatgca gtttggcttg
     9181 gctcataatg gaaatctgac caatgcagcc tctctcaaga aagaactgga acaaagagga
     9241 gcaattttca gcgcgacttc ggactctgaa atcttggctc acctcattcg tcgcagtcat
     9301 aatcctagcc tgatgggcaa aatcaaggaa gcgctcagcc ttgtcaaagg tggttttgcc
     9361 tatatcttgc tgtttgagga caagttgatt gcggctcttg accctaatgg ctttcgtccg
     9421 ctttctatcg ggaaaatggc caacggagcg gtggttgttt cctctgaaac ctgtgctttt
     9481 gaggtcattg gtgccgagtg gattcgtgat ttgaagccag gtgagattgt gatcattgat
     9541 gacgagggca ttcagtatga cagctataca gatgatactc agttggcgat ttgttctatg
     9601 gagtatatct actttgctcg ccctgattct aatatccacg gtgtcaatgt ccatacggca
     9661 cgtaagagaa tgggagcgca attggcgcga gaatttaagc atgaggcaga tattgtagtt
     9721 ggtgtgccca attcttccct aagcgcggct atgggatttg cggaagaatc aggcttacca
     9781 aatgaaatgg gtctgatcaa aaaccaatac acccagcgaa cttttatcca accgactcaa
     9841 gaattgcggg agcaaggagt gcggatgaaa ctgtctgctg tttcgggtgt tgtcaaaggc
     9901 aaacgtgtgg tcatggtgga tgattccatt gtacgtggaa caacctctcg tcgtatcgtt
     9961 cagctcttga aagaagcggg tgcgactgag gttcacgttg ccattggaag tcctgcacta
    10021 gcgtatccat gtttctacgg gattgatatc cagacccgtc aggagctgat tgcagccaat
    10081 catacggtcg aagaaactcg ccaaatcatt ggtgcggaca gtctgactta tctttcaatt
    10141 gatggcttga ttgagtcgat tggtatcgaa acagatgcgc cgaacggtgg tctctgtgtc
    10201 gcttactttg acggtgacta cccaacgcct ctctatgact acgaagaaga ctatcgtaga
    10261 agtttggaag aaaagaccag tttttacaag taggcgacag attctccatt aaagaaaagg
    10321 aaaaaacaaa tgacaaataa aaatgcatat gcccagtcgg gtgtggatgt tgaagcgggt
    10381 tatgaagttg ttgaacggat taaaaagcac gtggcccgta cggagcgtgc aggtgtcatg
    10441 ggagctcttg gtggctttgg tggtatgttt gacctttcca agactggggt taaagaaccc
    10501 gtcttgattt cagggactga cggtgtcgga accaagctca tgttggctat caagtacgac
    10561 aagcacgata ccatcgggca ggactgtgtg gccatgtgtg tcaacgacat cattgctgca
    10621 ggtgcggaac ccctctattt tctcgactac gtagcgacag ggaagaatga accagctaag
    10681 ctagaacaag tggttgctgg tgtggcagaa ggttgtgtgc aggctggtgc tgccctcatc
    10741 ggtggggaaa cggctgaaat gccgggcatg tacggcgaag acgactatga cttggctggt
    10801 tttgcggtcg gtgtggctga aaaatctcaa atcattgacg gttcaaaggt ggtagaggga
    10861 gatgttcttc tcggacttgc ttcaagtggg attcactcaa atggttactc tttggttcgt
    10921 cgtgtctttg cggattacac aggtgaggaa gtcctaccag aattggaagg caagaaactt
    10981 aaggaagttc tacttgagcc gactcgtatc tatgtcaagg ctgtcttgcc gctcatcaaa
    11041 gaagagttgg tcaacggcat tgcccacatc acaggtggtg gctttatcga aaatgtccct
    11101 cgtatgtttg cagatgacct agctgctgaa attgatgaaa gcaaagttcc agtgcttcca
    11161 attttcaaag cccttgaaaa atatggtcag attaaacacg aagaaatgtt tgaaatcttc
    11221 aatatgggtg tgggacttat gttggcggtc agccctgaaa atgtagagcg tgtaaaagaa
    11281 ttgttggatg aagcagtcta tgaaattggt cgcatcgtca agaaagaaaa cgaaagtgtc
    11341 attatcaaat gaaaaaaata gcggtttttg cctctggtaa tggctcaaat tttcaggtga
    11401 ttgccgaaga atttccagtg gagtttgtct tttcagacca tcgtgatgcc tatgtgcttg
    11461 agcgtgcaaa gcagctcggc gttctgtcct atgcttttga actcaaggag tttgagagca
    11521 agacagacta cgaagcagcc cttgtcgaac tcttggaaga acaccagatt gacttggttt
    11581 gcctagcagg ctacatgaaa atcgttggac caaccttatt gtcggcttat gaaggtcgga
    11641 ttgtcaacat tcatccagcc tacttgccag aatttccagg agctcatggg attgaggatg
    11701 cttggaatgc tggcgtgggt cagtctggtg tgaccattca ctgggtggat tcgggtgtgg
    11761 atacaggcca ggtcatcaaa caggttcgtg tgccacgact agctgatgat accattgaca
    11821 gatttgaagc tcgcatccat gaagcagagt acaggttgta tccggaagta gtgaaggctc
    11881 tatttacaga ttgacttttt gatgattcat atgatatctt tgattttaaa ttggagtcag
    11941 tgtttgttga agacggcttc aaacggaggt atttgtaatg ttagaatcta aaaaaacaac
    12001 tcgatatgta ttttatgtct atctgatgtt attaacttgg ggaatcttat ttaagtttga
    12061 aacaaatcct gaatttatag catttttctt agctccaagg tatatcaatt ggattccatt
    12121 ttcagaacca ctaatagtcg atggaaaaat tgtttttgct gaaatgttat ttaatctgat
    12181 ttcctttatt ccattaggtg tttgtttccc tttgataaaa actaatttat ctagtttaag
    12241 aatagtcggg acaggtttct tgattagttt attgtttgag tgcttacagt atattttagc
    12301 aataggtata acagatataa cggatttgac tttaaatacg ctaggtgtct gtgtaggctt
    12361 actgatttat caaattttta taagagtgtt caaatcacag actagaaaat ggatcaatat
    12421 cttaggtatg cttagccttg gttttgctta tcttgtttta ctgttactgc atttaattgg
    12481 tgtttaacta atgattaaaa aggagaatat aatgactaaa cgcgtcttaa tcagcgtctc
    12541 agacaaagcg ggcattgttg aatttgccca agaactcaaa aaacttggtt gggagattat
    12601 ctcaacaggt ggaactaagg ttgcccttga taatgctggg gtggatacca ttgctatcga
    12661 tgatgtgact ggtttcccag aaatgatgga cggtcgtgtg aagaccctcc acccaaatat
    12721 ccacggaggg cttctcgctc gtcgtgactt ggatagccac ttggaagcgg ctaaggacaa
    12781 caagattgag ctcattgacc ttgtggtggt caacctttac ccatttaagg aaactatcct
    12841 taaaccagat gtgacttatg ctgatgcagt tgaaaatatc gatattggtg ggccgtctat
    12901 gcttcgttca gcagcgaaaa atcatgccag tgttacagtt gtggtagatc ctgctgacta
    12961 cgctgtggtt ttggacgaat tggcagcaaa cggcgaaacc tcttatgaaa ctcgccaacg
    13021 tttagcagcc aaagtatttc gtcacacagc ggcttatgac gccttgattg cagaatactt
    13081 cacagctcaa gtgggtgaaa gcaagcctga aaaactcact ttgacttatg acctcaagca
    13141 accaatgcgt tacggtgaga atcctcaaca agacgcggac ttttaccaga aagctttgcc
    13201 tacagattac tctattgctt cagccaaaca gctcaacggg aaagaattgt catttaataa
    13261 tatccgtgat gcagatgctg ctatccgtat catccgtgac ttcaaagata gtccaaccgt
    13321 tgtggctctc aaacacatga atccatgtgg aattggtcaa gctgatgaca tcgagactgc
    13381 ttgggactac gcttatgagt ctgacccagt atctatcttt ggtgggattg tcgtcctcaa
    13441 ccgtgaggtg gatgctgcga cagctgagaa gatgcacggc gttttcctcg aaatcatcat
    13501 tgcaccaagc tatacggatg aagcgctagc tattttgatc aataaaaaga aaaacttgcg
    13561 tatccttgcc ttgccattta atgctcaaga ggctagcgaa gtggaagcag aatacacagg
    13621 tgtagtcggt ggacttctcg tgcaaaatca agacgtggtc aaggaaagcc cagctgactg
    13681 gcaagtggtg accaaacgtc agccaactga gacagaagcg actgctcttg agttcgcttg
    13741 gaaggctatc aagtacgtca aatcaaatgg tattatcgtg accaacgacc acatgacact
    13801 tggtgttggt ccaggtcaaa ccaaccgtgt ggcttctgtt cgccttgcca ttgaccaagc
    13861 caaagatcgt ctgaacgggg cggtccttgc ttcagatgcc ttcttcccat ttgcggataa
    13921 cgtggaagaa atcgccaaag caggaattaa ggccatcatc cagcccggtg gctctgtccg
    13981 tgaccaagaa ttcatcgaag cagcggataa atacggcttg actatggtct ttacaggtgt
    14041 gagacatttt agacattaag aagataaaag ggaagaaaac agtttctttc cttttttggc
    14101 ttaaaatgct aactgaaaca agattaaaac gaactttttt gatataatgt tggtaaataa
    14161 ttcgcaaaag aggttgagga atgaaactgc ttgttgtcgg ttctggtggt cgtgagcatg
    14221 cgattgctaa aaagttactt gaatcaaaag acgtggaaaa agtctttgta gctcctggga
    14281 atgacggtat gactctggat ggtctggaat tggtaaatat atctatttcc gaacattata
    14341 aattgattga cttcgcaaag gccaacgata ttgcttggac ctttatcggt ccagatgacg
    14401 cccttgcggc tggtatcgtg gatgatttcc atgcagctgg tctcaaagcc tttggtccga
    14461 caagattggc agcggagctg gagtggtcca aggatttcgc caaggaaatc atggtcaaat
    14521 atggtgtttc gacagcagcc tatggcacat tttcagattt cgaggaagca aaggcctata
    14581 tcgaaaagca tggtgcgcct atcgtagtca aggcggatgg cttggcgctt gggaagggtg
    14641 tcgtcgttgc tgagacggtt gagcaagcgg tcgaagccgc tcatgagatg cttttggaca
    14701 ataaatttgg tgactcaggt gcgcgcgtgg ttattgagga attccttgaa ggagaggaat
    14761 tttcactctt tgcctttgtc aatggtgata agttctacat catgccaacg gctcaggacc
    14821 acaaacgtgc ctacgatggc gacaaagggc ctaacacggg tggtatgggt gcctatgcgc
    14881 cagttccaca cttaccacag agtgtagttg atacagcggt tgacaccatt gtcaagccag
    14941 ttctagaagg gatgattaaa gaaggtcgcc cttatctggg agttctttac gcagggctta
    15001 tcctgacagc tgatggaccg aaagtcattg agttcaacgc tcggttcgga gatccagaaa
    15061 ctcagattat cttgcctcgc ttgacctctg actttgctca aaatatcaca gatatcctgg
    15121 atagcaagga gccaaatatc atgtggacgg acaagggtgt gactctgggt gtggttgtcg
    15181 catccaaggg ctacccgcta gactatgaaa ggggcgttga gttgccagcc aagacagaag
    15241 gcgatgtcat cacctactat gcaggggcta agtttgcgga aaatagcaga gcactgctct
    15301 caaacggcgg acgagtttat atgctcgtta ccacagcaga taccgtcaaa gaagcccaag
    15361 ccagcatcta ccaagaacta tcccaacaaa aaatagaagg actcttctac cgaacagata
    15421 tcggaagcaa ggcaattaag taaagatata agaataacgc gccgtagtcg ccaaacacga
    15481 taatggtcgt cgtggtgaaa agaccagaac agtgaatgtt ctggtcaggg ggaaacttgg
    15541 agaccgtagg ctcaaagttt aggaatgaaa ccgaaggttt gcttccgcct ccatcaccta
    15601 agaccattat caaaaagaaa aataaaaatt cacaaaatac gttaatgatc gtatggttag
    15661 cgagctaata tagaacaatc accgccgttg tgaaagaacg attggatgat aatccaatcg
    15721 ttcagggaaa ttggaagacc ttgggtttcc aatttaggca tgagacacct ttggtggctg
    15781 ctgccgtccc tcacaagcta aggtgattgt tgaaaaagag gaaaaaggag aagaaatgaa
    15841 accagtaatt tccatcatca tgggctcaaa atccgactgg gcaaccatgc aaaaaacagc
    15901 agaagtccta gaccgcttcg gtgtagccta cgaaaagaaa gttgtttccg cacaccgtac
    15961 accagacctc atgttcaaac atgcagaaga agcccgtagt cgtggcatca agatcatcat
    16021 cgcaggtgct ggtggcgcag cgcatttgcc aggcatggta gctgccaaaa caacccttcc
    16081 agtcattggt gtgccagtca agtctcgtgc tcttagtgga gtggattcac tctattctat
    16141 cgttcagatg ccgggtgggg tgcctgttgc gaccatggct atcggtgaag ctggagcgac
    16201 taacgcagct ctctttgccc tccgtctcct ctctgtagaa gataagtcca ttgcggatgc
    16261 acttgccaac tttgctgaag aacaaggaaa aatcgcagag gagtcgtcaa atgagctcat
    16321 ctaaaacaat cggaattatc ggtggcggtc aactgggtca gatgatggcc atttctgcta
    16381 tctacatggg ccacaaggtt atcgcgctgg atcctgcggc ggattgcccg gcctctcgcg
    16441 tggcggaaat cattgtggca ccttataacg atgtggacgc cctccgtcag ttggcagacc
    16501 gttgcgatgt cctcacttat gagtttgaaa atgtcgacgc tgacggtttg gatgccgtta
    16561 tcaaggatgg acaactccct caaggaacag atctgctccg catttcgcaa aatcgtattt
    16621 ttgaaaagga ctttttgtca aacaaggctc aagtcactgt ggcaccctac aaggtcgtga
    16681 cttctagcct agacttggca gatatcgact tgtcgaaaaa ctatgtcctc aagactgcga
    16741 ctggtggcta cgatggtcat ggacaaaagg ttattcgttc agaagcagac ttggaagcag
    16801 cctatgcgct agcagactca gcagactgcg tcttggaaga atttgtcaac tttgaccttg
    16861 agatttctgt catcgtgtca ggaaatggca aggaggtgac gtttttccca gttcaggaaa
    16921 atatccaccg caacaatatc ctgtctaaga ccatcgtacc agcccgcatt tctgaaagtc
    16981 tagtagacaa ggctaaagct atggcagtgc gaatcgcaga acaactcaac ttgtctggaa
    17041 ctctctgtgt ggaaatgttt gcgactgatg atgacgttat tgtcaatgaa atcgccccac
    17101 gaccacataa ctctgggcac tattctattg aagcctgtga tttctctcag tttgacaccc
    17161 atattctcgg tgttctcgga gcaccattac cagtcatcaa actccatgcg cctgccgtca
    17221 tgcttaacgt tctcggccag catgttgagg ccgctgaaaa atatgtcaca gaaaattcaa
    17281 gcgcccacct ccacatgtat ggtaaaatag aagcgaagca caaccgcaag atgggacatg
    17341 tgactttgat tagtaatgaa ccagatagtg tgggagagtt ttaggggaga ggggtctaaa
    17401 gaaaaaatgt ttgaaaaaat taaaggaatt aatataaaat caggtatttt tgaagatgaa
    17461 acaaaattag aactctttga aggaaatttt gagggaacaa atccagtaca aaacgatagg
    17521 gcaagtttat tgtttggaag gaatggttca gggaaaagta ccattgctcg aggaataaat
    17581 caattaaaaa atggtgagat tggaacagat agagtatcat ttattgataa aaataataat
    17641 aatattgtac ttagtgatac tgaacgaaaa tcgatatttg ttttcaatga acactatgtt
    17701 gatcagaaag tcaaaattgc tcaagaaggg ttagatacaa ttgtaatttt aggtgaacag
    17761 gttgatatcg atgaggaact ggatagatta agaacgcagt tatcagaatc acaaattgaa
    17821 tctcaagatt attatgctga atatgaagaa tatttagatg aaaaaaatga aaaatctcca
    17881 gatttttgga aaaaggaaat gacagattct ttgaaaggag taggcaactg ggccgaaaga
    17941 gatagggaga taaaaggaaa tcgagctgca tctcccgttc ataataatac ctttcaaaat
    18001 tttgttgatt tacaaccaat cttagataaa aatgagttag aggttgaatt caacaataaa
    18061 aaagctagat atttttcaat aagagattcc gcagttacta taaataatga actatcttta
    18121 cctgatatta attttgatag caatgaatta tcaactttat tgtctgaaaa aatcgaagaa
    18181 cctgagttga attctaggga taagtattta ctgacattat tatctgattc cacaaaaggt
    18241 gaacgtcatt tgagagaagt taaagatttc tttgaagatg aacatcaaaa aaaatgtcct
    18301 ttctgtactc aatcagtatc agaagatgtt aaagttgaac tcacgaatgg cataactaaa
    18361 ctactatcaa gagcagtcga agaacaccaa tccgcattga gaggtaaaaa aattgatgag
    18421 attaatcaag atttttctgg ttatgaacag atagatccaa tattaattca gtcttatcaa
    18481 aatagtatta atgctttgaa tgctaaattt aacgaaatta actcaataat cgataagaag
    18541 attgataatc catataatat agttgagtta cctaatataa gcttttctca agaattaagt
    18601 caagcagagc atgatattga aaaaattaac caagcaatta tcaaacataa ttcagaaatc
    18661 tcgggtattc aaaagttaaa agtagatctc cttcaaataa ataatgaatt agctttttat
    18721 gaaattcaag atgcatacaa aaagtttcaa gagaaaacaa ataaaaaagc aatttgtgaa
    18781 aataattata ataacagtag taaacgagta aaggattatg agaagcagat ttctgattta
    18841 gaagacaaga aacttaatat agatattgca gttgatgaaa ttaataaaag tttaaattac
    18901 atattttttt caaaaaatcg gttagctata cagaatcaaa acggaaaata ctatctgtta
    18961 tcaagaggta agtctgtggt ccccagtagg gtttccgtag gggaacgaaa tgcgctggca
    19021 ttatgttatt tctttactga gataattcaa cagagagagt tagcagatgc ttatagtcat
    19081 gaatatttta ttgttattga cgatccaatt tctagttttg atatggaaaa taaagttgga
    19141 ataacctcgt atttaaaata ttgtttaact agatttttta aggggaatag taatactaga
    19201 gttttactaa tgacccatga taaacaaaca atatatgact ttgatatctt tttgaaagag
    19261 ataatggaat cctgtaaaga agaggaaggt ggacaaaaat ctaaatacaa gaagttagaa
    19321 ttggtttctg gtaaattaca agaattcaaa actagtactc acgattatac agaactactt
    19381 gaaatagtct tcggttatgc attgggaaat agtacaccta cttcggaaag ttttgttggg
    19441 aatgcaatga gaaaaatttt agaagcctat ggtagtttta attataagaa gggaattgcc
    19501 gagctaacaa cagatccttt aattgttgaa aaaattgata aagaatacag aacttatttt
    19561 gagaatctta tgtatagact ggttttaaac ggtgaaagtc attttaagga tccggttaaa
    19621 actttgagta ttgatttctt tgataccatt tctgatgaag aacgaaaaaa aacagctaga
    19681 gatttactag ttttgcttta tcttttagat gatttacatg ttttaaaaca tttagagggt
    19741 gtatcaaatg cggaaaatag acttgaacaa tggaagtgtg agattttaga ataagagaat
    19801 cataccattt gacttattgc aatggttgaa gtttgcatga tagctgatta gagtaatcaa
    19861 aggattatta cttcctaatt ttattttcta caaaccctaa tttagcatct aataatgcaa
    19921 agtttcctga gcctcataga taaaaaagat ttttaaggag aaaaacatga tcaaccgtta
    19981 ctctcgccct gagatggcga atatttggag tgaagaaaat aaataccgtg cttggcttga
    20041 ggtggaaatc ctctctgacg aggcatgggc tgagttgggg gaaatcccta aggaagatgt
    20101 ggctttgatt cgcaagaagg cggactttga catcgaccgt attttggaaa ttgagcagga
    20161 gacgcgccac gatgtggtgg ctttcacgcg tgcggtttct gagactcttg gtgaagagcg
    20221 caagtgggtt cactatgggt taacttctac cgacgtggtg gatactgcct atggttacct
    20281 ctacaagcag gccaacgaca tcatccgtcg tgaccttgaa aacttcacta atatcatcgc
    20341 tgacaaggcc aaggagcaca agttcaccat catgatgggg cgtactcatg gtgtgcacgc
    20401 tgagccgaca acttttggtc ttaaattggc aacttggtat agcgaaatga aacgcaatat
    20461 cgagcgcttc gagcatgcgg ctgctggtgt agaagctggt aagatttctg gtgcggttgg
    20521 gaactttgcc aatatcccac catttgtaga ggagtatgtc tgcgataaac ttggcatccg
    20581 tgcccaagaa atctctacac aagtccttcc tcgtgacctt cacgctgagt actttgcggt
    20641 tcttgccagc attgcgactt caatcgaacg tatggcgact gagattcgtg gtctacaaaa
    20701 atctgagcaa cgcgaagtag aagagttctt tgctaaaggg caaaaagggt cttcagcaat
    20761 gcctcacaaa cgcaacccaa tcggttctga aaatatgact ggtctggcgc gtgtcattcg
    20821 tggtcacatg attacggctt atgaaaacgt cgctctctgg cacgaacgcg atatttctca
    20881 ctcatcagct gagcgtatca tcacaccaga tacgaccatt ttgattgact acatgctcaa
    20941 ccgttttgga aatatcgtca agaacttgac agtcttccca gaaaatatga tccgaaacat
    21001 gaactcgact tttggtctta tctttagcca acgggctatg ttgacattga ttgaaaaagg
    21061 catgacccgt gagcaagcct atgacttggt gcaaccaaaa acagcctact cttgggacaa
    21121 ccaagtagac tttaaaccac ttcttgaggc agattcagaa gtaacatcac gtctcacaca
    21181 agaagaaatc aatgaaatct tcaacccaat ttattacacc aaacgagtgg atgatatctt
    21241 tgaacgtctt ggactaggtg attaattaaa aaataaacag cgagcttcaa tctcgctgtt
    21301 tattttttat cgaaaagact tagtcttctt ttcttttagt gagtccatag gctgctagtg
    21361 tggacatgag tcctgcgact actagtcctg cagaatcgtg agttcctgtt tcaggaagtt
    21421 ttttctctgt taccacagga gctggatctt gaggaagagc tttgctttcc tcagcaggag
    21481 cagttgatgg agctggttgg cttgggattt ctagtcttgg tttttcttca gcaatagcgg
    21541 cttgtccgtt ttcatcgcct acatgtgtta ccatagttcc gacttcgact atttgagtaa
    21601 cggcttcctg tgctacgaca ctatttacaa gtgttttcac ttccttacca tcggcagaag
    21661 tgctcacaga gtagaagttg ctacgatgtc cattgacgcc cttagtaatg acttgtgttt
    21721 ttcctttgag taagagtgga ttttcacgag tcactgtggt aaatggaatt tcttcttttt
    21781 ggatatccag tctaggtttt acctcagtag ttggtgcaag accactttca tcacccttgt
    21841 gagttacagg agcgccaact tcaaccactt ggtttataac ttctttggtt acctggctat
    21901 caaggactgt ttctgttgtt tttccatttt cagtgagtac agagatgtaa tgagttcgtt
    21961 cacctttgac tcctgctgtg ataatatttt cctgaccagc tgggaggtta ggattttctt
    22021 tcttgataac ttcaaatgga atttcttcag ttcttgtgat gagttctggt ctggtttcaa
    22081 cattggcagc cacttcattt tcatccaggc ttcctgaatg agttgcagct ggtttgaggc
    22141 cttgaagagc ggcttttagg ttggctacaa gtgtgtcaag ctcagcttgt ttattacggt
    22201 tgaggttgta atttagagct gttttagctg cgtcaagggc ctcaagactt tctttactat
    22261 atccttctaa gtttgtagga attttagcta attcttcgcg gagagcatta taattagcac
    22321 ggaagtagtc tttgttgtgg tctgcaaagg cagtcatgag ttcaaagatt tcctcttcct
    22381 tgtactcagc gcttggtcta tctgcccaga ttgaaagcat acttccgact gttggaagat
    22441 ctacttcagg atatttggta gaagctagtt gattgaatgg aactttacca gaattttcaa
    22501 ctgcttttga aagagggtaa gcttcatctt gtttgtgatt gcctataaca taataccagt
    22561 caccgttggt attcaagaat ttatagcctt tgcttgctag gtattgaggt gatgcgaggt
    22621 tatatcccca ccagccttta gaccagtaag aaatcaagac atctttgtca aactgaacat
    22681 cgtccttgtc ttcatagtag aagccatcgt tgaaggccat tggttgaagc cctctttctt
    22741 tggccatagc tgcgagggtg ttggcatatt cggcaaattt gccatagagt tgataccact
    22801 tgaggtagta ccagccttgg gcactagtcg catcgttggc gtattcgtca gtaccaaagt
    22861 tgaaaatctt tgttttacct gcaaagaagt ccatgtattt accgatgagg gcttttacaa
    22921 agttcatcgc ttcttcgttt ttcaagtcca tagttgtttt tgaaacttta tcaaagtggg
    22981 cttgaggatt tttaatacct aatttttcca tggcaaccag catagcatcc atgtgacctg
    23041 gactgttaat agctgggatg agaccaatgt ccttagattt agcgtattca attagctctg
    23101 tcacttctgc ctgtgttagt gcagtaccgt ttggatcgtc gtagtaagct ttagttcctt
    23161 cgataatagc ttttttaacg tcatcactag cataggtttt tccgttggca gtaatggtca
    23221 tatcattgag tagaaagcga agtccgtcat ttcctagaag gagatggaca tcagaatatc
    23281 cgagctcact ggccttgtct acgatgcgtt tgagctggtc cagagtaaag tatttgcgtc
    23341 cagcatcgat tgagattacc ttgtttttgg caagtttttc aacctcacgt ttagcttctt
    23401 cttctttttg agcttcaggc gtgagggtca agttgttgac agtttcttga agtttagcaa
    23461 tggcttgatc aatcgtatct tgttgggcac ggctaaggtt gctatcgaga gagcgaatag
    23521 ctttttcagc ttcttttacg gccgtgacgc tttctgcagt ataacggttc aggtcttttg
    23581 gtacctcgtt aagtgcttgc tctgcagatt cataatcagc tgcgaagtat tcagcgttgg
    23641 catttgcaaa atgacgcatg agtttgaaga ggcgtgatgg tgaataacgt gcagatggag
    23701 tgtcagccca agcagctacc ataccaccga tgattgggat atcagctcct tctgtttttg
    23761 gtacagaagt gattggtgtg tttttaatac cattgagccc ctgatcgaga ttgtaccagc
    23821 cttggccatc agcgtttcgt ccaagaacgt agtaccaagc atcattggta ttaaggattt
    23881 ggtgaccttt ttcagctagt agtttagaag aagcgacatc gtagcctccc caaccaccag
    23941 tccacataga aacgatgatg tctttgtcaa aactaccaaa gcttgtgtcg ctattgtagt
    24001 agataccgtc gttaaaggcc attggtttga gaccgtgcga ttttacaata cgagcgaggt
    24061 cattggcgta ggcaataaat ttttcatagc cttttacagg gtagccttcg tttggatagt
    24121 atttatcagc ttgaagcaca ctccaacctt tagcatctgt cgcatcattg gcatattcat
    24181 caagtccgat gttgaagatt tcagtctttt tcgcgaaata agcagcatac ttgtcgataa
    24241 gggcttttgt aaaagcgaca gcttgttcgt tgtcaagatc gacagtacgg gctgatttct
    24301 tcccaaaata gctaaagtta gggttttgga ttcccaattc tttcatggca ttgagaatcg
    24361 catccatgtg tccaggacta tttactgtcg gaatgagacc gataccttta tctttggcat
    24421 agttaatcag atctgtcatt tgactttctg ttaagtgatt gccgtttgga tcgttgtaat
    24481 aatcatttgt acctttttca atggcgcgtt tgacatcgtc actggcatag gtcttgccgt
    24541 tagctgtgat gctcatatcg tccaacatga aacggagtcc atcatttccg actaataggt
    24601 gtaaatcagt gtagccataa tgtttcgctt tatcgatgat ttccttgagc tgttctggtg
    24661 agaaatattt acgtccagca tcaatagaaa caattttctt tttcgctagt ttttcattta
    24721 cagttgcagc acgttccttt cctgtctctg tttccggttt gtcagcctct gctttcgctt
    24781 catctttttt agctggttta tccttgtcag tcttgtctgt atttgactct ttagaatcaa
    24841 cctctttcgc ttcttccttt ttagggctag cttcttcttc ctttttatta gcagtttctt
    24901 tttcagcaga agttggagtt accacctctg ctttatcact aggagttgaa ctaacttcct
    24961 cttgtggttt ttcttctgtt tttggaagac tagctacctt atcagtagct ggagtttctg
    25021 tttctacagt ttttggagct tctggttgaa gctctgcttt aggtgtttcc tcagtccgat
    25081 tttcggatga ttgaggggaa tcagaaaccg tatggatggt cggttggttt tctgtagtag
    25141 taggagtaac tccatcggct gcaacagtct gtgcttggaa ggcaaatcca attagaacag
    25201 aagctgctcc tacagcgtat ttacgaatag aaaaacgctg ttgtttttca tgtttcattg
    25261 caaaacctcc tgattgcatt gttatattga tagcgattat ataaatcaac gcctttattt
    25321 tatttcttat attaacgaga gtcaagagga gatgacaaaa aactataata agtataaaaa
    25381 aatataaaat ttaaacttaa gatttcagat tggtcgaaaa aatacatata tatatctagt
    25441 ataatttttg gttctatttc tataaaatat tccacaaatt atagaatctt ccaaaaatag
    25501 gtaagcgcta cctttttggt gtggtataat aagcatagaa aaagcccgag cgattaggct
    25561 caggctttct tcttagtgat cacggtcaca tgagatgaat ttaatcttgt agtaatcaga
    25621 tcgtttgtaa gtttcactgt attctaaaac ttggccagtt gattcgagtt tggtgatttt
    25681 agtttgtagg acagtaggga attgttcatc gactccgagg actgaagccg catgttctgg
    25741 agttggaaag actatttcgt tgatttcttc aaagtgttca tcattcatgt gaatgtggta
    25801 gtctaacttg aaacgattat agatagaact atagtattca aggtttggat aatttgcgtt
    25861 gatatattgt tctgggatgt aggatgtatg gtagatataa acgacaccgt ttgattcgcg
    25921 gatacgttca atcttgtagt agaattgatc gccgcgtaga cccaattttt ccaagtaaac
    25981 aagcttgttt ccgcgttcaa ttgaaagaac agttacctta tcatctttag cattgaagag
    26041 ttcaatatct gaaaactcta caagcttgtg tttgcgtgca cgtgaaacga aggttccttt
    26101 tccttgttgg cggacaatat agccatcttt ggcaaggtcg tttaaggcgc gaacaactgt
    26161 gatagagctg acatcgtaca ttgaaatgag ttctgcttca gtgtaaaatt tatctccact
    26221 gctaaactgc ccagagatga ttttattttt taattcgtct tttatgtatt gatatttggg
    26281 aattgccata tttttacctc tattttcctt ctccatagaa aattttacca taaaagcgaa
    26341 aaaaatagta gtcttttgaa taaaaaatta gaataatagt t
//
LOCUS       DAVKBK010000024        22355 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVKBK010000024 DAVKBK010000000
VERSION     DAVKBK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.024"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..414
                     /locus_tag="VWX69_001120"
     CDS             <1..414
                     /locus_tag="VWX69_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192476.1"
                     /translation="YIKVTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIM
                     SFLLFLPIAIFMQICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQ
                     STTNLGIKLLVCIWIMGFEFFLLPKLIKLKEQNLV"
     gene            956..1177
                     /locus_tag="VWX69_001121"
     CDS             956..1177
                     /locus_tag="VWX69_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9192477.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            1694..1947
                     /locus_tag="VWX69_001122"
                     /pseudo
     CDS             1694..1947
                     /locus_tag="VWX69_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2075..3304
                     /locus_tag="VWX69_001123"
     CDS             2075..3304
                     /locus_tag="VWX69_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9192478.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            3324..6020
                     /gene="ppc"
                     /locus_tag="VWX69_001124"
     CDS             3324..6020
                     /gene="ppc"
                     /locus_tag="VWX69_001124"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU9192479.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    6103..6320
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6433..7437
                     /locus_tag="VWX69_001125"
     CDS             6433..7437
                     /locus_tag="VWX69_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9192480.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7506..8372
                     /locus_tag="VWX69_001126"
     CDS             7506..8372
                     /locus_tag="VWX69_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9192481.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8369..9127
                     /locus_tag="VWX69_001127"
     CDS             8369..9127
                     /locus_tag="VWX69_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192482.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            9217..10977
                     /gene="dnaG"
                     /locus_tag="VWX69_001128"
     CDS             9217..10977
                     /gene="dnaG"
                     /locus_tag="VWX69_001128"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU9192483.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10980..12089
                     /gene="rpoD"
                     /locus_tag="VWX69_001129"
     CDS             10980..12089
                     /gene="rpoD"
                     /locus_tag="VWX69_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU9192484.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            12103..12432
                     /locus_tag="VWX69_001130"
     CDS             12103..12432
                     /locus_tag="VWX69_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9192485.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12547..13590
                     /gene="cpoA"
                     /locus_tag="VWX69_001131"
     CDS             12547..13590
                     /gene="cpoA"
                     /locus_tag="VWX69_001131"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU9192486.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13606..14931
                     /locus_tag="VWX69_001132"
     CDS             13606..14931
                     /locus_tag="VWX69_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU9192487.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14962..15138
                     /locus_tag="VWX69_001133"
     CDS             14962..15138
                     /locus_tag="VWX69_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9192488.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            15197..15331
                     /locus_tag="VWX69_001134"
     CDS             15197..15331
                     /locus_tag="VWX69_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU9192489.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15395..16705
                     /gene="obgE"
                     /locus_tag="VWX69_001135"
     CDS             15395..16705
                     /gene="obgE"
                     /locus_tag="VWX69_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU9192490.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16715..16873
                     /locus_tag="VWX69_001136"
     CDS             16715..16873
                     /locus_tag="VWX69_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192491.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17960..19219
                     /locus_tag="VWX69_001137"
     CDS             17960..19219
                     /locus_tag="VWX69_001137"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9192492.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            19235..19786
                     /locus_tag="VWX69_001138"
     CDS             19235..19786
                     /locus_tag="VWX69_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192493.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            19779..21056
                     /locus_tag="VWX69_001139"
     CDS             19779..21056
                     /locus_tag="VWX69_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9192494.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFWVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            21072..21932
                     /locus_tag="VWX69_001140"
     CDS             21072..21932
                     /locus_tag="VWX69_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU9192495.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         6866 a         3807 c         4939 g         6743 t
ORIGIN      
        1 tatataaaag taacgataaa tatcgtgaga tgttttattt gttattttgt ttatacaatt
       61 ttttctttaa ttcaattagg tggtatggga actgatatgt tattaaccaa tataatattt
      121 cccaatataa tgtcatttct tttattttta cctatagcta tctttatgca aatttgctgt
      181 ataagatttg attccatttt agcaaaggcc ttacctaata ttttgctgat acttattgtt
      241 ttaatcacgt ttcagagtga ttggaatata tttatacctg caacttatta ttatacagaa
      301 attcagtcaa ctacaaactt aggtattaaa ttattagttt gtatctggat tatgggattt
      361 gaatttttcc ttcttccaaa actaataaaa ttgaaagaac aaaatctagt ttaaatgttg
      421 ctcgaaaatt aaataattga atacgattaa caatgaaaca atacaacgtg agtcatgact
      481 tcaaagtaat tgattttatg attctggttt cttacgctta attaagcaag ttgtattcac
      541 tttatcaaat tgttattact ctaaaaagcg tctaacagct atagagtgtc tgtttgcttc
      601 tctttacttt tattttaaat aattcattaa ccttccgtaa gtgcccaata ataaggtgtg
      661 ttgaagaagt ctgagataaa atagttctca gtcacaaaaa agctatagat tcccattggt
      721 gaacagctcc ctgtcaagta gacagtaaaa taatataaaa tcttaagcga cctgattcct
      781 gaattccagt ggagtcaggt tgttttttaa ccgtctttct taatattgtc ttacctataa
      841 tagatatgct tatgagatat gtttaataaa ttaattttag ttcaaaatgt ccagttagga
      901 cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa gctagatgta
      961 cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa tagctaaaat
     1021 actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata cgttaacagc
     1081 agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc tattggaatt
     1141 gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc atagagtgtg
     1201 aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat ggtactttcc
     1261 tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa aaccatcaat
     1321 aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata cttctgaccg
     1381 ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt catcagtcat
     1441 gccacgttaa atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa ggttccccga
     1501 accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct aaaagcgtaa
     1561 aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa tacaataaaa
     1621 ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc cttgtaggtg
     1681 ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg taaacgcgca
     1741 aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac tattcaatac
     1801 atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca cgaaagcaac
     1861 ttaatccgtc ggagccaatg ggttgaagta actcttgttc aaaatggttt tacgatttca
     1921 aattctgccc taattatgaa aaacagtaaa attcgaagga ttgtaaggta agagtttttt
     1981 tctttctgaa aaaatggtat aatagcaatc aaaactagaa aataaaacgg aatttggaac
     2041 agatttgtct gtatcctagt agagtggtga tgctatgaag attagtaaga ggcacttatt
     2101 aaattattcc atcttgattc cctacttgct tttatctatt ttgggcttga ttgtggtcta
     2161 ttcgaccacc agtgctattt taattgaaga aggcaagagc gccttgcagt tggttcgaaa
     2221 ccaaggaatc ttttggattg ttagtttgat actgattgcc ttaatttata aattgagact
     2281 agattttttg agaaatgagc gactaatcat tttagttata ttaatagaaa tgcttttatt
     2341 gttcttggct cgttttattg gtatttccgt aaacggggca tacggttgga tttcggttgc
     2401 aggagtaact attcagccag ctgagtactt aaaaatcatt attatttggt atttagctca
     2461 ccgattctcc aaacagcaag aagaaatagc tacttatgat tttcaagttt tgactcaaaa
     2521 tcaatggctt ccccgtgctt ttaatgattg gcgattcgtt ctcctagttc tgattggaag
     2581 tttgggaatt ttccctgatt taggaaatgc gactatttta gtcttggttt ccttgattat
     2641 gtatacagtt agtggaatcg cttatcgctg gttttcaacc attctggcgc tcgtatctgc
     2701 cgcttctgtc tttgtcttga ccactatcag cctaatcggt gttgagacct tttcaaaaat
     2761 tccagtattt ggctatgtag ccaagcgctt tagtgccttt tttaatcctt ttgccgatcg
     2821 tgctgatgca ggtcaccagt tagctaattc ttattttgcc atggtcaatg gtggttggtt
     2881 tggtctaggt cttggaaact cgattgaaaa acgaggttat ttgccagaag ctcatacaga
     2941 ctttgtcttt tctatcgtga ttgaagaatt tggctttgct ggtgccagtc ttattttagc
     3001 tctcttgttt ttcatgattt tgcggattat cttggtcggt attcgagcgg agaatccttt
     3061 caatgccatg gttgcactcg gtgtcggagg gatgatgttg gttcaggtat ttgtcaatat
     3121 cggagggatt tcgggcttga ttccatctac aggagtaacc ttccccttct tatcccaggg
     3181 tggaaatagt cttctagtct tatcagtggc agtagccttt gtcttaaata ttgatgccag
     3241 tgaaaaacgc gctaagttgt accgagaatt ggaaaatcaa ccaatgaacc ttctgttgaa
     3301 gtaggataaa gaaaggatag tttatgtctc ttcaaaaatt agaaaattat agtaataaaa
     3361 gtgttgtgca agaagaagtc ttgattctaa cagaattact ggaagatatt actaaaaata
     3421 tgcttgcccc agagaccttt gaaaaaataa tacagttgaa agaattatca acgcaggaag
     3481 attatcaagg tctaaaccgt ctagtgacta gcttatcaaa tgatgaaatg gtctatattt
     3541 cacgctattt ctctatctta cctcttttga tcaatatttc agaggatgtg gatttagctt
     3601 atgaaatcaa tcatcaaaat aatattgatc aggactattt aggtaaatta tctacaacga
     3661 ttaaattggt agcagaaaag gaaaatgccg ttgagatcct agaacacttg aatgttgtcc
     3721 ctgttttgac agcccatcca acacaagtgc aacgcaaaag tatgttggat ttaacaaatc
     3781 atattcatag tcttttgcgt aaataccgtg atgttaagtt ggggttgatc aataaagata
     3841 aatggtacaa tgatttgcgt cgttacatcg aaattatcat gcagacagac atgattcgtg
     3901 agaaaaaatt aaaagtgact aacgaaatca cgaatgctat ggaatattat aacagctcct
     3961 ttttgaaagc tgtacctcat ttgacgacgg agtataagcg cttagcgcaa gcgcatggtc
     4021 tgaatttaaa acaggctaaa ccaatcacca tgggtatgtg gataggtggt gaccgtgatg
     4081 gaaatccatt tgttacagca gagaccttga agcagtctgc actcactcaa tgtgaagtca
     4141 tcatgaacta ctatgataaa aagatttacc aactttatcg tgaattttct ctttcaacta
     4201 gcattgtcaa cgtcagcaag caagtcagag aaatggctcg tcaatccaag gataactcga
     4261 tttaccgcga aaaagagctt taccgtcgtg ccttgtttga tattcaatca aaaattcagg
     4321 caactaaaac ctatctgatt gaggatgaag aagttgggac tcgttatgaa accgccaatg
     4381 atttctacaa ggatttgatt gccattcgag attctctact agaaaataag ggtgagtcct
     4441 tgatttcagg tgattttgtg gaattattgc aggcagtaga gatatttggt ttttacctag
     4501 catcaattga tatgcgacaa gactctagcg tctatgaagc ctgtgtggca gaactcttga
     4561 aatcagcagg aattcattct cgttatagcg agttgagcga agaagaaaag tgtgaccttc
     4621 tcttgaaaga attagaagaa gatccccgaa ttctttctgc gactcacgca gaaaaatcag
     4681 aattattagc aaaagaatta gctattttta agacggctcg tgttttgaaa gataagttgg
     4741 gagatgatgt catccgtcag accatcattt cacatgcaac cagcctttct gatatgctag
     4801 aattagctat tctgttaaaa gaagtaggac tggtggatac ggaaagggcg cgtgttcaga
     4861 ttgttcccct ttttgaaaca attgaagact tggatcattc agaagaaaca atgagaaaat
     4921 atctttctct tagccttgcc aaaaaatgga ttgactcacg aaataactac caagaaatca
     4981 tgcttggcta ctctgacagt aataaagatg gcggttactt gtcatcatgt tggaccctct
     5041 acaaggctca acaacaattg actgctattg gagatgaatt tggcgttaag gttaccttct
     5101 tccatggtcg tggtggtact gtcggtcgtg gtggtgggcc aacctatgaa gccattacat
     5161 ctcaaccgct caagtctatc aaggatcgta tccgcttgac ggagcagggt gaagtaattg
     5221 ggaataaata cggtaacaaa gacgccgctt actataacct tgaaatgcta gtatcggcag
     5281 ctattaaccg tatgattact cagaagaaga gcgataccaa taccccaaat cgttatgaag
     5341 ccattatgga tcaagtagtg gaccgtagtt acgatatcta ccgtgatttg gtctttggta
     5401 atgagcattt ctatgattat ttcttcgagt caagtccaat caaggctatt tcaagtttta
     5461 atattggttc tcgtccagcc gctcgtaaga ctattactga aatcggtggt ttgcgtgcca
     5521 tcccttgggt attctcatgg tcacagagtc gtgttatgtt ccctggatgg tacggggttg
     5581 gttcaagctt caaggaattt atcaataaaa atccagagaa tattgctatc ttacgagata
     5641 tgtaccaaaa ttggcctttc ttccaatcgc ttctttcaaa tgttgatatg gttttgtcaa
     5701 aatcaaatat gaatattgct tttgaatatg ctaaactttg tgaagacgag caagttaagg
     5761 ccatctatga gactatttta aatgaatggc aagttactaa gaacgttatc ttggctattg
     5821 aaggacatga cgaactctta gctgacaatc catatctaaa agctagtctg gattaccgta
     5881 tgccttactt taatattctc aactatattc agttagagtt gattaaacgc caacgtcgtg
     5941 gagaattgtc cagtgatcaa gaacgattga ttcatatcac catcaacgga attgcgacag
     6001 gattgcgtaa ttcaggttga taattttcaa gagtgaatgc taaaagtgaa tatcaaaaaa
     6061 attctaatag actattgaca agtagtttaa aaatgatata atttaaccat tcagaaaagt
     6121 aatcatacaa actttttaga gagtctgtgg tagctgaaaa cagataagtg gcgatgatga
     6181 aaattgggct gaatgctatt tagaatttga aattataaaa attcggtaag cacaccttac
     6241 agtgcatctc gttattgcga gactgagcga tagggaaatt ccctataatt gaggtggtac
     6301 cgcgcatcga cgtcctcaca caagtttttt gtgtgaggat ttttttgatg gaggttagta
     6361 tggaaagaaa acgatggcgt cgcttgttta gataagtgaa atatgttaaa ggaaataaaa
     6421 aggagaaaca gaatgaaaaa taaacgttta attggaatta ttgctgcatt agcagtctta
     6481 gtagcaggaa gcttgattta ttcttcaatg aataaatcag aagctcagaa taataaggat
     6541 gagaagaaaa taactaagat tggtgtgctt caatttgtga gccatccatc ccttgatttg
     6601 atttataaag ggatccaaga tggacttgca gaagaaggat ataaagatga tcaagttaaa
     6661 attgatttta tgaactcaga aggtgaccaa agtaaggttg cgacaatgag taaacaattg
     6721 gttgcaaatg ggaatgacct tgtggttggt atcgcaacac cagcagccca agggttggct
     6781 agtgcaacaa aagacctacc ggttatcatg gccgctatta cagacccaat tggtgctaac
     6841 ttggttaaag atttgaaaaa accaggtggc aacattacag gggtatctga ccacaatcca
     6901 gctcaacaac aagttgaact catcaaggct ctgacaccga atgtgaaaac aatcggagct
     6961 ctttactcaa gtagcgaaga caattcaaaa acacaggtcg aagaatttaa ggcttatgct
     7021 gaaaaagcag gtctgacagt ggaaacattt gcagttcctt caacaaatga aattgcctca
     7081 actgtcactg ttatgactag caaggtagat gctatttggg ttccaattga taacaccatt
     7141 gcatcaggat ttccaacggt tgtctctagc aatcaaagtt ctaagaaacc aatttatccc
     7201 agtgcgacag ctatggtaga agtaggtggt ttggcatcag ttgtaattga ccaacatgac
     7261 cttggtgtgg caacaggtaa aatgattgtg caagtcttga aaggtgcaaa accagccgat
     7321 accccagtca atgtcttttc aactggtaag tcagtcatca ataaaaaaat agcacaagaa
     7381 ctaggtatta ctattcctga gtctgttctc aaagaagcag gacaagtcat cgaataaata
     7441 aggtagggag gaggagactc ttcccatttt ttaaaaagat gaatatagaa aggattaaat
     7501 aaaatatgat tgtttccatt atttctcaag gatttgtctg ggctattcta ggtctgggaa
     7561 tctttatgac atttaggatt ttaaactttc cagatatgac gacagaaggt tccttccctc
     7621 ttgggggagc tgttgctgtc actttgataa ccaaaggcgt gaacccattt ttagcgacac
     7681 ttgttgctgt aggagcaggt tgtttggctg gaatggcagc aggccttctt tatacaaaag
     7741 ggaagatccc aaccttgcta tcagggattt tggtgatgac ttcttgtcac tcaatcatgc
     7801 tcttgattat gggacgtgcg aatttaggcc tgcttggaac caagcaaatt caggatgttt
     7861 tgccttttga ttcggatttg aatcaactct tgacaggtct catctttgtg agtattgtta
     7921 ttgctctcat gctctttttc ttggacacta aactcggaca agcctatatt gctacagggg
     7981 ataatcctga tatggctaga agtttcggga ttcatactgg acgcatggag ctcatgggct
     8041 tggtcttatc aaatggtgtg attgcccttg caggtgccct cattgctcag caagaaggtt
     8101 atgccgatgt gtctcgaggg atcggggtta tcgttgtggg gcttgcaagt ttgattattg
     8161 gagaagttat tttcaagagt ttgagcttgg cagagcgttt ggttactatc gttgtaggtt
     8221 ctatcgctta tcaattttta gtgtgggcag ttatcgcact tggctttaat acaagttacc
     8281 ttcgtttata cagtgccttg attttagcag tctgcctcat gattccaaca tttaagcaaa
     8341 caatcttgaa aggagccaag ttaagcaaat gacagcaatt gtagaattaa aaaatgcaac
     8401 caaaatcgtt aaaaatggct ttgatgaaga aaagattatt ttaaatgatg tttccttaga
     8461 aatttttgaa cgggacttta tcacgatttt gggcggaaat ggtgctggaa aatcaaccct
     8521 ctttaacact atagcaggga ccttatcact aactagtgga actatccgta ttttaggtga
     8581 agaactcact aagttttcac ccgagaagcg tgccaagtac ctgtctcgtg tcttccaaga
     8641 tccaaagatg gggacagctc cccgtatgac ggtcgctgaa aatcttttaa tcgccaagtt
     8701 tcgtggtgaa aagcgtggat tgttaccacg acgcttgact agctataagg atgaatttca
     8761 ggcaaccatt gaaaaagtag gaaatggtct tgagaaacac ttgaatacac cgattgagtt
     8821 cttatcaggt ggacaaagac aggctttgag tctcttgatg gcaaccttga agcgacctga
     8881 attactcctg ttagatgagc atactgctgc cctggatcca aagactagtg ttgctttgat
     8941 ggaattgaca gatgaatttg ttaagaaaga tcagctaaca gcccttatga ttactcatca
     9001 tatggaagat gctctcaaat acggcaatcg cttgattgtc atgaaagaag gacggattat
     9061 ccaagattta aaccaagaag aaaaagcaaa aatgaaaatc tctgattatt atcaactctt
     9121 tgaataaagt agggaaaatg agtgaaatgg tttacttttt ttctgaaata aagtatacta
     9181 tataaagtaa actatgataa catggaggta ttgtgtatgg ttgacaaaca agtcattgaa
     9241 gaaatcaaaa acaatgccaa cattgtggaa gtcataggag atgtgatttc tttacaaaag
     9301 gcaggacgga actatctagg gctctgtcct tttcatggtg aaaaaacacc ttctttcaac
     9361 gttgtagagg ataagcagtt ttatcactgt ttcggttgtg gtcgctcagg tgatgtcttt
     9421 aagttcatcg aggagtacca aggggttccc tttatagagg cagtccaaat cttaggtcag
     9481 cgtgttggaa ttgaggttga aaaaccgctt tatagtgagc agaagccagc ctcacctcac
     9541 caagctcttt atgatatgca cgaagatgca gccaaatttt accatgcgat tctcatgaca
     9601 acgactatgg gcgaagaggc cagaaattac ctttatcagc ggggtttgac agatgaagtg
     9661 cttaaacatt tttggattgg tttagcacct ccagaacgaa actatctcta tcaacgtttg
     9721 tctgatcagt atcgtgaaga ggatttactg gattcaggcc tgttttatct ctcggatgcc
     9781 aatcaatttg tagacacctt tcacaatcgc attatgtttc ccctgacaaa tgaccaagga
     9841 aaggtcattg ccttctcagg tcgtatctgg caaaaaacgg attcacaaac ttctaagtat
     9901 aaaaacagcc gatcgactgc aatttttaac aaaagttacg aattatatca tatggatagg
     9961 gcaaaaaaat cttctggaaa agctagtgag atttacttga tggaaggatt catggatgtt
    10021 attgcagcct atcgggctgg aatcgaaagt gctgtggcgt cgatgggaac ggccttgagt
    10081 cgagagcatg ttgagcatct gaaaaggtta accaagaaat tggttcttgt ttacgatgga
    10141 gataaggctg ggcaagccgc gacattgaaa gcattggatg aaattggtga tatgcctgtg
    10201 caaatcgtca gcatgcctga taacttggat cctgatgagt atctacaaaa aaatggtcca
    10261 gaagacttgg cctatctatt aacgaaaact cgtattagtc cgattgagtt ctacattcat
    10321 cagtacaaac ctgaaaacag tgaaaatctg caggctcaga ttgagtttct tgaaaaaata
    10381 gctcccttga ttgttcaaga aaagtccatc gctgctcaaa acagctatat tcatatttta
    10441 gctgacagtc tggcgtcctt tgattatacc cagattgagc agattgttaa tgagagtcgt
    10501 caggtgcaaa ggcagaatcg catggaagga atttccagac cgacgccaat caccatgcca
    10561 atcaccaagc agttatcggc tattatgagg gcagaagccc atctactcta tcggatgatg
    10621 gaatcccctc ttgttttgaa cgattaccgt ttgcgagaag actttgcatt tgctacacct
    10681 gaatttcagg tcttatatga cttgcttggc cagtatggaa atcttcctcc agaagtttta
    10741 gcagagcaga cagaggaagt tgaaagagct tggtaccaag ttttagctca ggatttgcct
    10801 gctgaaatat cgccgcagga acttagtgaa gtagagatga ctcgaaacaa ggctctcttg
    10861 aatcaggaca atatgagaat caaaaagaag gtgcaggaag ctagccatgt aggagataca
    10921 gatacagccc tagaagaatt ggaacgttta atttcccaaa agagaagaat ggagtaataa
    10981 tggcaacaaa acaaaaagaa gtaacaacat ttgacgtaca ggtagcagaa tttatccgta
    11041 atcataagca aaaagggaca gcaacagatg atgaaatcaa tgcaagtctg gttattcctt
    11101 ttaccttgga cgctgatggg attgaagatc tcttgcaacg gattcaggat gcaggaattt
    11161 ctatcacaga taacgaagga aatccaagtg cgcgtgttct tagcaatgaa gaagaaccag
    11221 aactcagcga tgaggacttg attgggtcaa cttctgctaa ggtcaatgac cctgtccgta
    11281 tgtacttgaa agaaataggg gtcgttcctc tcttgaccaa tgaagaggag aaagagttgg
    11341 cactggctgt tgaagctggt gatatcgaag ccaaacaacg tcttgcggaa gccaatcttc
    11401 gtttggttgt ttccattgcc aaacgctatg tcggtcgtgg catgcagttc cttgacttga
    11461 ttcaagaagg aaatatgggc ttgatgaagg cggttgacaa gtttgactat tctaaagggt
    11521 tcaagttttc aacttatgca acttggtgga ttcgtcaggc tatcactcgt gctattgcgg
    11581 accaagctcg taccatccgt atcccagttc acatggttga aactatcaat aaattggttc
    11641 gtgaacagcg gaatctcctt caagaattgg ggcaagatcc gacaccagaa cagattgctg
    11701 aacgaatgga tatgacacct gataaggttc gtgaaatctt gaagattgcc caagaaccag
    11761 tatctcttga aactcctatc ggtgaagagg acgatagcca ccttggagac tttatcgaag
    11821 atgaagtgat tgaaaatcca gtggattata cgactcgtat cgtcttgcgt gagcaattgg
    11881 atgaaatctt agatactctt acagaccgtg aagaaaatgt tctgcgtcta cgttttggac
    11941 tagatgatgg aaaaatgcgc acacttgaag atgtggggaa agtctttaac gtaactcgtg
    12001 agcgtatccg tcagattgaa gcaaaggctt tgagaaaact acgccaacca agtcgtagca
    12061 aaccgcttcg tgattttatt gaagactaag agtgaggaaa atatggctta tacagaagag
    12121 caaattgaaa acatcaaaac acggatttta acagccttgg aagaagtcat cgaccctgag
    12181 ttgggaatcg atattgtcaa tcttggtttg atctatgaga ttcgttttga cggtgacaca
    12241 gggcaaacag agattgacat gactttgaca actatgggtt gtcccttagc agaccttttg
    12301 acagaccaga tttatgatgc tatgatagag gttccagaag taacggatac tgaggttaaa
    12361 ttagtctggt atccagcctg gacagttgaa aaaatgagtc gctatgcccg cattgcccta
    12421 ggcattaagt aaacatataa aagcatgtga gagactgttg gaaaagcgag gaaatttccc
    12481 ctcttttcct ctagtctctc ctttcttttg ctgattttat tcaaagaaaa tgatataata
    12541 gtagttatgg agaaaaagaa attacgcatc aatatgttga gttcaagtga gaaagtagca
    12601 ggacagggag tttcaggtgc ttaccgtgaa ttagttcgtc ttcttcaccg tgctgccaag
    12661 gaccaattga ttgttacaga aaatcttcca atcgaggcag atgtgactca ctttcatacg
    12721 attgattttc cctattattt atcaaccttc caaaagaaac gctcagggag aaagattggc
    12781 tatgtgcatt tcttgccagc tacacttgag ggaagtttga aaattccatt tttcttaaag
    12841 ggaattgtga aacgctatgt attttctttt tacaaccgga tggagcactt ggttgtggtc
    12901 aatcctatgt ttattgagga tttggtagca gctggtattc cacgtgaaaa agtgacctat
    12961 attcctaact ttgtcaacaa ggaaaaatgg catcctctac cacaagaaga ggtagtcaga
    13021 ctgcgcacag atcttggtct tagtgacaat cagtttatcg tagtaggtgc tgggcaagtt
    13081 cagaaacgta aagggattga tgactttatc cgtctggctg aggaattgcc tcagattacc
    13141 tttatctggg ctggtggctt ctcttttggt ggtatgacag atggttatga acactataag
    13201 aaaattatgg aaaatccccc taaaaatttg atttttccag gcattgtatc gccagagcgg
    13261 atgcgcgaat tgtatgctct agcggatctt ttcttgttgc ctagttacaa tgagctcttt
    13321 cctatgacta ttttagaagc tgcgagttgt gaggctccta ttatgttgcg tgatttagat
    13381 ctctataagg taattttgga gggaaattat cgggcgacag cgggtagaga agagatgaaa
    13441 gaggctattt tggaatatca agcaaatcct gctgccttaa aagatctcaa agaaaaggct
    13501 aagaatattt ccagagagta ttctgaagag catctgttac aaatctggtt ggacttttat
    13561 gagaaacaag ccgctttagg gagaaagtaa aaagtgaggt aatctatgcg aattggttta
    13621 tttacagata cctattttcc tcaggtttct ggtgttgcga ccagtattcg aaccttgaaa
    13681 acagaacttg aaaagcaggg acatgctgtt tttatcttta cgacgacaga taaggatgtc
    13741 aatcgctacg aagattggca aattatccgc attccaagtg ttcctttctt tgcttttaag
    13801 gatcgtcgct ttgcctaccg aggttttagc aaggcacttg aaattgctaa acagtatcag
    13861 ctagatatta tccatactca gacagaattt tctcttggcc tgttggggat ttggattgcg
    13921 cgtgaattga aaattccagt catccatacc tatcacaccc agtatgaaga ctatgtccat
    13981 tatattgcta aggggatgtt gatccggccg agtatggtca agtatctggt tagaggtttc
    14041 ctgcatgatg tggatggggt tatttgtcct agtgagattg tccgtgactt gctatctgat
    14101 tataaggtca aggttgaaaa acgggtcatt cctactggga ttgaattagc caagtttgag
    14161 cgtccggaaa tcaagcagga aaatttgaaa gaactgcgta gtaaactagg gattcaagat
    14221 ggtgaaaaga cgttgcttag tctttcgaga atctcctatg aaaaaaatat tcaagcagtt
    14281 ttagcagcct ttgctgatgt tctgaaagag gaagacaagg ttaaactggt agtagctggg
    14341 gatggccctt atctgaatga cctcaaagag caagctcaga acctagagat tcaagactca
    14401 gtcatcttta cagggatgat tgctcctagt gagacggctc tttactataa agcggcggat
    14461 ttcttcattt cggcatcgac aagcgaaacg caaggtttga cctacttgga aagcttagcc
    14521 agtggaacac ctgtcattgc tcacggaaat ccttatttga acaacctcat cagtgataaa
    14581 atgtttggaa ccttgtacta tggagaacat gatttggctg gtgctatttt ggaagccctg
    14641 attgcaacac cagacatgaa cgagcatacc ttatcagaga aattgtatga gatttcagct
    14701 gagaactttg ggaaacgagt gcatgagttt tatctggatg ccattatttc aaataacttc
    14761 cagaaagatt tggctaaaga tgatacggtc agtcagcgta tctttaagac agttttgtat
    14821 cttcagcaac aggtggttgc tgtacctgta aaaggatcta gacgcatgtt gaaggcttca
    14881 aaaacacagt tgatcagtat gagagactat tggaaagacc atgaagaata gaaagaggaa
    14941 cagctatgaa aaaaacaatt aatgagaagc ggtcgtgata aaaagattgc gggtgtttgt
    15001 gctggggtgg cccattatct ggatatggat ccgactatcg ttcaagtcat ttggggtgtt
    15061 cttacttgct gttacggagc tggaattgta gcttacatta ttttatggat tatcgcacca
    15121 gtagcaactg actattgaaa actagctcaa ttcatgctaa gataatagaa aatagaatgt
    15181 aacgaaggag agaaaaatgg catttggaga taatggaaat cgtaaaaaaa ctatgtttga
    15241 gaaaataacc ttgtttatcg tgattatcat gctagtagca agtttattgg gaatttttgc
    15301 aactgcaatt ggtgccctca gtaatctata aaatagattc aagaaaattt agtgactggg
    15361 atttcccagc ccttttttaa agtgagaaga aataatgagt atgtttttag atacagctaa
    15421 gattaaggtc aaggctggta atggtggcga tggtatggtt gcctttcgtc gtgaaaaata
    15481 tgtccctaat ggaggccctt ggggtggtga tggtggtcgt ggaggcaatg tggtcttcgt
    15541 tgtagacgaa ggactacgta ccttgatgga tttccgctac aatcgtcatt tcaaggctga
    15601 ttctggtgaa aaagggatga ccaaagggat gcatggtcgt ggtgctgagg accttagagt
    15661 tcgagtacca caaggtacga ctgttcgtga tgcggagact ggcaaggttt taacagattt
    15721 gattgaacat gggcaagaat ttatcgttgc ccacggtggt cgtggtggac gtggaaatat
    15781 tcgtttcgcg acaccaaaaa atcctgcacc ggaaatctct gaaaatggag aaccaggtca
    15841 ggaacgtgag ttacaattgg aactaaaaat cttggcagat gtcggtttag taggattccc
    15901 atctgtaggg aagtcaacac ttttaagtgt tattacctca gctaagccta aaattggtgc
    15961 ctaccacttt accactattg taccaaattt aggtatggtt cgcacccaat caggtgaatc
    16021 ctttgcagta gccgacttgc caggtttgat tgaaggggct agtcaaggtg ttggtttggg
    16081 aactcagttc ctccgtcaca tcgagcgtac acgtgttatc cttcacatca ttgatatgtc
    16141 agctagcgaa ggccgtgatc catatgagga ttacctagct atcaataaag agctggagtc
    16201 ttacaatctt cgcctcatgg agcgtccaca gattattgta gctaataaga tggacatgcc
    16261 tgagagtcag gaaaatcttg aagaatttaa gaaaaaattg tctgaaaatt atgatgaatt
    16321 tgaagagtta ccagctatct tcccaatttc tggattgacc aagcaaggtc tggcaacact
    16381 tttagatgct acagctgaat tgttagacaa gacaccagaa tttttgctct acgacgagtc
    16441 cgatatggaa gaagaagctt actatggatt tgacgaagaa gaaaaagcct ttgaaattag
    16501 tcgtgatgac gatgcgacat gggtactttc tggtgaaaaa ctcatgaaac tctttaatat
    16561 gaccaacttt gatcgtgatg aatctgtcat gaaatttgcc cgtcagcttc gtggtatggg
    16621 ggttgatgaa gcccttcgtg cgcgtggagc taaagatggg gatttggtcc gcattggtaa
    16681 atttgagttt gaatttgtag actaggagac tggtatggga gataaaccga tatctttccg
    16741 agatgcggat ggtaattttg tttccgccgc agacgtttgg aatgaaaaga aattggaaga
    16801 actatttaat cgtctcaatc caaatcgtgc cttgagattg gcacgaacta aaaaggaaaa
    16861 tccatctcag taaagaagct aaaaaatccc gtgcctcatc agacacggga ttttgtggta
    16921 cgacaggcat gtatagcaaa ctgaatctgg aatagcacag catatcttct aaaatattgc
    16981 tataaattga tttgaatttc aaaattaaat tgttttattc ttatttcaat ttgttatagt
    17041 atatctgatg tcaaagttct cggcgagtca aatagtgatt cccaagcctg actatcgtga
    17101 ggtagcggat taaaatggtc tggggataga ccgttttaag tctgatgctg gaaataagaa
    17161 ttgtcagaag aagggatagc gaaatcgtgg ctctacgaac aggaacgtga taataaggcg
    17221 tatatagcga ataagagggc ctcaaactct aaagtccaaa aaggtagtcg taacctatat
    17281 gcgtaaatca tgagagtaat tgaattcgta ctaagatttt ctatttttac tgtaaccttt
    17341 taacgtcctc atatcttgta tacacgagga aagatgtacg acttatcccg tgaggtctat
    17401 cactataaag agaaaacgac agatagaagt gatcctgagt cacggttatc tttaaaatag
    17461 attgtctgat aggatgctag cctgaaaacg tcttgttcat gaaatatagg acggtatgta
    17521 taaaacgctt ctgtgaactg agagaagggg gagaagttct tgctaaaatt tagttgaaca
    17581 gccgtattcc gatacttaga taagagatct agtcttagct cctactcagt ttcaggggat
    17641 aaaaaagggg caatagcgat tcgagaaaga ttatactctt cgaaaatctc ttcaaatcac
    17701 gtcaatatcg ccttgccgta tgtgtaggat actaactacg tcagttccat ctacaatctc
    17761 aaaacagtgt tttgagcaac ctgcggctag tttcctagtt tgatctttga tttttattga
    17821 gtattagtaa ttcagttact aactcgtcaa ctctgattta tccaataaaa ttgaaaagga
    17881 tggaaaaaag gataaattta tgatatactt tattttgaag accttattag aaatcttgaa
    17941 agagtattga aaacttagaa tgagaaaaat tgttatcaat ggtggattac cactgcaagg
    18001 tgaaattact attagtggtg ctaaaaatag tgttgtggcc ttaattccag ctattatatt
    18061 ggctgatgat gtggtgactt tggattgtgt tccagatatt tcggatgtag ccagtcttgt
    18121 cgaaatcatg gaattaatgg gagctactgt taagcgttat gacgatgtct tggagattga
    18181 tccaagaggt gttcaaaata ttccaatgcc ttatggtaaa attaacagtc ttcgtgcatc
    18241 ttactatttt tatgggagcc tcttaggccg ttttggtgaa gcgacagttg gtctaccggg
    18301 aggatgtgat cttggtcctc gtccgattga cttacacctt aaggcgtttg aagctatggg
    18361 tgccactgct agctacgagg gagataacat gaagttatct gctaaagata caggacttca
    18421 tggtgcaagt atttacatgg atacggttag tgtgggagca acgattaata cgatgattgc
    18481 tgcggttaaa gcaaatggtc gtactattat tgaaaatgca gcccgtgaac ctgagattat
    18541 tgatgtagct actctcttga ataatatggg tgcccatatc cgtggggcag gaactaatat
    18601 catcattatt gatggtgttg aaagattaca tgggacacgt catcaggtga ttccagaccg
    18661 cattgaagct ggaacatata tatctttagc tgctgcagtt ggtaaaggaa ttcgtataaa
    18721 taatgttctt tacgaacacc tggaagggtt tattgctaag ttggaagaaa tgggagtgag
    18781 aatgactgta tctgaagaca gcatttttgt cgaggaacag tctaatttga aagcaatcaa
    18841 tattaagaca gctccttacc caggctttgc aactgatttg caacaaccgc ttacccctct
    18901 tttactaaga gcgaatggtc gtggtacaat tgtcgatacg atttacgaaa aacgtgtaaa
    18961 tcatgttttt gaactagcaa agatggatgc ggatatttcg acaacaaatg gtcatatttt
    19021 gtacacgggt ggacgtgatt tacgtggggc cagtgttaaa gcgaccgact taagagctgg
    19081 ggctgcacta gtcattgctg ggcttatggc tgaaggtaaa actgaaatta ccaatatcga
    19141 gtttatctta cgtggttatt ctgatattat cgaaaaatta cgtaatttag gagcggatat
    19201 tagacttgtt gaggattaaa ccgtagaggt gtttatgaat atttggacca aattagcaat
    19261 gttttctttt tttgaaacgg atcgcttgta tttgcgtcct ttctttttta gtgatagtca
    19321 ggacttccgc gagatagctt caaatccaga aaatcttcaa tttattttcc caacgcaggc
    19381 aagtctggaa gaaagtcaat atgcactggc caattacttt atgaagtccc ctttgggagt
    19441 gtgggcaatt tgtgaccaga aaaatcaaca aatgattggt tctattaaat ttgagaagtt
    19501 agatgaaatc aaaaaagaag ctgagcttgg ctattttttg agaaaagatg cttggtcgca
    19561 aggatttatg acagaggttg ttagaaaaat ttgtcagctt tcttttgagg aatttggctt
    19621 aaaacaatta tttatcatta cccaccttga aaatgaagct agccaaagag ttgctcttaa
    19681 gtctggattt agtttgttcc gtcagtttaa gggaagtgat cgttacacaa gaaaaatgcg
    19741 ggattatctt gaatttcggt atgtaaaagg agagttcaat gagtaagcat caggaaattc
    19801 taagctattt ggaggaatta ccagtaggta aaagggtcag tgttcgtagc atttcgaatc
    19861 atctaggagt tagtgatgga acagcctatc gagctattaa agaagctgaa aaccgtggaa
    19921 ttgtggagac ccgtcctaga agtggaacaa ttcgtgttaa atcccagaaa gttgctatag
    19981 agagattaac gtttgctgaa attgcagaag tgacttcttc tgaggttctg gctgggcaag
    20041 aaggtttaga gagagagttt agtaagtttt caattggtgc catgactgaa caaaatatct
    20101 tgtcttacct tcatgatggg gggctcttga ttgtcggaga ccgaacccgt attcagttgc
    20161 tagccttgga aaatgaaaat gcagttctgg ttacaggggg atttcaggtt catgatgatg
    20221 tgcttaaact ggccaatcaa aaagggattc ctgttctaag aagtaagcat gataccttta
    20281 ccgtcgcgac catgatcaat aaagccttgt caaatgtcca aatcaagact gatattctga
    20341 cagttgagaa actttatcgc cctagtcatg agtatggttt tctgagagag acagatacag
    20401 ttaaagatta tttggacttg gttcgtaaga atcgtagcag ccgtttccct gttatcaatc
    20461 aacatcaggt cgttgttggt gttgtaacca tgagagacgc tggtgataaa tcaccaagca
    20521 cgacaattga taaggttatg tctcgtagtc tattttgggt tggattatcg acaaatattg
    20581 ccaatgtgag tcaacggatg atcgcagaag actttgaaat ggtaccagtt gttcgaagca
    20641 atcaaacttt gcttggcgtt gtgacgcgac gagatgtcat ggagaagatg agccgttccc
    20701 aagtttcggc tctaccaact ttttctgagc agattggaca aaagctctct tatcaccatg
    20761 atgaagtagt cattacagtg gaacccttta tgctagaaaa aaatggagtt ttggctaatg
    20821 gtgtattggc agaaattctg acccacatga cccaagattt agttgttaat agtggtcgca
    20881 atctcattat cgagcagatg ctgatctact ttttgcaggc tgttcagata gatgatatat
    20941 tgcgcattca ggcacggatt attcatcata cgagacggtc agctataatt gattacgata
    21001 tttatcatgg tcaccagatt gtttcaaaag caaatgtgac tgttaaaatt aattagaaac
    21061 taggagaaaa gatgataaca ttaaaatcag ctcgtgaaat cgaagctatg gacaaggctg
    21121 gtgattttct agcaagtatt catataggct tacgtgattt gattaagcca ggcgtagata
    21181 tgtgggaagt tgaagaatat gtccgccgtc gttgtaaaga agaaaatttc cttccacttc
    21241 agattggggt tgacggtgcc atgatggact atccttatgc tacctgttgc tctcttaacg
    21301 atgaagtggc tcacgctttc cctcgtcatt atatcttgaa agatggtgat ttgctcaaag
    21361 ttgatatggt tttgggaggt cccattgcta aatccgacct gaatgtctca aaattaaact
    21421 tcaacaatgt tgaacaaatg aaaaaataca ctcagagcta ttctggtggt ttagcagact
    21481 catgttgggc ttatgctgtt ggtacaccgt ccgaagaagt caaaaacttg atggatgtaa
    21541 ccaaagaagc tatgtacaag ggtattgagc aagctgttgt tggaaatcgt atcggtgata
    21601 tcggtgcggc tattcaagaa tacgctgaaa gtcgtggtta cggtgtagtg cgtgatttgg
    21661 ttggtcatgg tgttggccca actatgcacg aagaaccaat ggttcctaac tatggtattg
    21721 caggtcgtgg actccgtctt cgtgaaggaa tggtcttaac cattgaacca atgatcaata
    21781 caggcgattg ggaaattgat acagatatga aaactggttg ggcgcataag accattgacg
    21841 gtggattgtc atgtcagtat gaacaccaat ttgtcattac gaaagatgga cctgttatct
    21901 tgactagcca aggtgaagaa ggaacttatt aataaaaagt gaaaagacta ctggaagttt
    21961 attttgataa aaaatccagt agatcttttc ataataaaac gcattgtatc aagtgttagg
    22021 agctgatatc atgcgttttt ctgcttttaa gattttttcc aactctgttt gtaagcgcat
    22081 cataacaaag ggtctaggat tcagggctct cctcctatat actattagta aagtaaaact
    22141 aagagaggat attttagtgt cgcagtctat tgttcctgta gagattccac aatattgtcg
    22201 ttttgattct aaaaagagaa atggaattct gtttaacgtt cgtattgcca atcttaaatt
    22261 tacctttttt agattagact tcctgcgaaa taaaatatgg tatagtagtt ctatgaatga
    22321 tgaagcaagt aaacaactaa ctgatgcacg attta
//
LOCUS       DAVKBK010000025        22189 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVKBK010000025 DAVKBK010000000
VERSION     DAVKBK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22189
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.025"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..178)
                     /gene="blpI"
                     /locus_tag="VWX69_001141"
     CDS             complement(<1..178)
                     /gene="blpI"
                     /locus_tag="VWX69_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEU9192496.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGS"
     gene            460..1047
                     /locus_tag="VWX69_001142"
     CDS             460..1047
                     /locus_tag="VWX69_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU9192497.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            974..2617
                     /locus_tag="VWX69_001143"
     CDS             974..2617
                     /locus_tag="VWX69_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU9192498.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2628..3989
                     /locus_tag="VWX69_001144"
     CDS             2628..3989
                     /locus_tag="VWX69_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU9192499.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4046..4174
                     /gene="blpC"
                     /locus_tag="VWX69_001145"
     CDS             4046..4174
                     /gene="blpC"
                     /locus_tag="VWX69_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU9192500.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(4245..5585)
                     /locus_tag="VWX69_001146"
     CDS             complement(4245..5585)
                     /locus_tag="VWX69_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9192501.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5599..6336)
                     /locus_tag="VWX69_001147"
     CDS             complement(5599..6336)
                     /locus_tag="VWX69_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9192502.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6341..6679)
                     /locus_tag="VWX69_001148"
     CDS             complement(6341..6679)
                     /locus_tag="VWX69_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9192503.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6955..7284
                     /locus_tag="VWX69_001149"
     CDS             6955..7284
                     /locus_tag="VWX69_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9192504.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7452..8501)
                     /locus_tag="VWX69_001150"
     CDS             complement(7452..8501)
                     /locus_tag="VWX69_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9192505.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8498..9229)
                     /locus_tag="VWX69_001151"
     CDS             complement(8498..9229)
                     /locus_tag="VWX69_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192506.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9297..9707
                     /locus_tag="VWX69_001152"
     CDS             9297..9707
                     /locus_tag="VWX69_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU9192507.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9717..10004
                     /locus_tag="VWX69_001153"
     CDS             9717..10004
                     /locus_tag="VWX69_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192508.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10166..10450
                     /locus_tag="VWX69_001154"
     CDS             10166..10450
                     /locus_tag="VWX69_001154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192509.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTDEVSSKHCFEVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(10762..11898)
                     /gene="dnaJ"
                     /locus_tag="VWX69_001155"
     CDS             complement(10762..11898)
                     /gene="dnaJ"
                     /locus_tag="VWX69_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU9192510.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12300..12656)
                     /locus_tag="VWX69_001156"
     CDS             complement(12300..12656)
                     /locus_tag="VWX69_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEU9192511.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVPAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12658..14481)
                     /gene="dnaK"
                     /locus_tag="VWX69_001157"
     CDS             complement(12658..14481)
                     /gene="dnaK"
                     /locus_tag="VWX69_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU9192512.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14961..15485)
                     /gene="grpE"
                     /locus_tag="VWX69_001158"
     CDS             complement(14961..15485)
                     /gene="grpE"
                     /locus_tag="VWX69_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU9192513.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15512..16546)
                     /gene="hrcA"
                     /locus_tag="VWX69_001159"
     CDS             complement(15512..16546)
                     /gene="hrcA"
                     /locus_tag="VWX69_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU9192514.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16710..17219)
                     /locus_tag="VWX69_001160"
     CDS             complement(16710..17219)
                     /locus_tag="VWX69_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU9192515.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17827..20160
                     /locus_tag="VWX69_001161"
     CDS             17827..20160
                     /locus_tag="VWX69_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9192516.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20173..21636
                     /locus_tag="VWX69_001162"
     CDS             20173..21636
                     /locus_tag="VWX69_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9192517.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21636..>22189
                     /locus_tag="VWX69_001163"
     CDS             21636..>22189
                     /locus_tag="VWX69_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9192518.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLL"
BASE COUNT         7048 a         4499 c         4097 g         6545 t
ORIGIN      
        1 ctgaacctac acaaataagt gttgctgctc ccccagttat cggaccagtc gcagcagcta
       61 atagtactgc tccaatacaa ccaccgattg cagatcctaa attgcctctt cctccactaa
      121 ctatttcgag ttcttcatta tccataacag aaaattgttc catcattttt gtattcatga
      181 caaatactcc ttttttcttt ttttattttt gtcttgttgt aactttgata agtttagtat
      241 atcatcgttt tttaaaattt ttcatccaga tcttgaattg tcatcgaaac gtcttgaatt
      301 aggtttttta tttcaagcca cctctaaatg tttaaaaaaa ataatttcta atcacttttt
      361 taccattcag gaagttttaa tgactattca agatttcata aaatatgaac ttagttttat
      421 gacataatag acctatccac tatatgaaag gaattgccaa tgacttctta taaacgtaca
      481 tttgttcctc aaatagatgc gagagactgt ggtgtcgctg ccttagcctc gattgctaaa
      541 ttctatggtt cagatttttc tctagctcac ttgagagaac ttgcaaagac caataaagaa
      601 gggacgactg ctcttggcat tgtaaaagcc gctgatgaaa tgggctttga aacaagacct
      661 gttcaagcag ataaaacgct ctttgacatg agtgatgtcc cctatccatt tatcgttcac
      721 gttaacaaag aaggaaaact ccaacattac tatgttgtct atcaaacaaa gaaagactat
      781 ctgattattg gtgatcctga cccttctgta aaaatcacta aaatgtcaaa agaacgcttt
      841 ttctatgaat ggactggagt agctattttt ctagctacca aacccagcta tcaaccccat
      901 aaagataaaa agaatggtct actaagcaag cttccttcct ctgattttca aacaaaaatc
      961 tctcattgct tacattgttc tctcaagctt attggtcact attatcaata taggtggttc
     1021 ttactatctc caaggaatct tggatgaata cattccaaat cagatgaaat caactttagg
     1081 aatcatctca gttggtctgg ttatcaccta tatcctccaa caagtcatga gcttctccag
     1141 agattatctc ctaaccgttc tgagtcagag attaagtatt gatgtgattt tatcctatat
     1201 tcgccatatt tttgaacttc ccatgtcttt ctttgcgaca cgtcgtacag gagaaatcat
     1261 ttcacgattc acagatgcta actctattat agatgccttg gcttctacca ttctttctct
     1321 ttttctggat gtttctattc tgattcttgt aggaggcgtc ttactggcac aaaaccctaa
     1381 tctcttcctt ctttctctta tttccattcc tatatacatg ttcatcatct tttcttttat
     1441 gaaacctttc gaaaaaatga accatgatgt catgcaaagt aattctatgg ttagctctgc
     1501 cattatcgaa gatatcaacg ggattgaaac tataaagtcg ctcacgagtg aagaaaatcg
     1561 ctatcaaaat atagacagcg aatttgtaga ttatttggaa aaatccttta agctcagtaa
     1621 atattctatt ttacaaacga gtttaaagca gggaacaaaa ttagttctga atatccttat
     1681 cctatggttt ggcgctcaat tagtcatgtc gagtaaaatt tctatcggtc agctgattac
     1741 ctttaacaca cttttttctt actttacaac tcctatggaa aatattatca acctccaaac
     1801 caaactccaa tctgcgaagg tcgctaataa ccgtttgaac gaagtctatc tagtcgaatc
     1861 tgaatttcaa gttcaagaaa accctgtcca ttcacatttt ttgatgggcg atattgaatt
     1921 tgatgacctt tcttataagt atggttttgg acgagatacc ttaacagata ttaatctcac
     1981 gattaaacaa ggagataagg ttagcctagt tggagttagt ggttctggta aaacaacttt
     2041 agccaaaatg attgtcaatt tctttgaacc ctacaaagga catatttcta tcaatcatca
     2101 ggatattaaa aacattgata aaaaagtctt gcgccgtcat attaattacc taccacaaca
     2161 agcctatatc tttaatggct ctatcttgga aaacttaact ttgggcggta atcatatgat
     2221 tagccaagaa gatattctaa gagcttgtga attagctgaa attcgtcaag acattgaaag
     2281 aatgcctatg ggctatcaaa ctcagctctc tgatggagct ggtctatcag gaggacaaaa
     2341 gcaacgaata gccctcgctc gtgctctttt aactaaagct cctgttttaa tactagacga
     2401 agctactagc ggtcttgatg tcttgactga gaaaaaggtt atagataatc ttatgtctct
     2461 aactgataaa accattctct ttgtagccca tcgtctcagt atagccgaac gaaccaaccg
     2521 tgtcattgtt cttgaccagg ggaaaatcat tgaagttggt agtcaccaag agttaatgca
     2581 ggcgcaaggt ttctaccatc atctattcaa taaataagga gaatgtcatg aatcctaatc
     2641 tttttagaag cgtcgagttt tatcagagac gttaccataa ctatgcgaca gtgttcatta
     2701 tacctctttc attactattt actttcatct tgattttctc ccttgttgcc acaaaagaaa
     2761 ttactgttac ttcccaagga gaaatcgccc ctacaagtgt cattgcctcc attcagtcaa
     2821 ccagtgataa tcctatccta gctaatcatt tagtggcaaa tcaagtagtt gaaaaagggg
     2881 acttactcat caaatactct gaaacaatgg aagaaagtca gaaaactgcc ttagcaactc
     2941 aattacaaag acttgagaag caaaaagaag gacttggaat tttgaaacaa agcttagaaa
     3001 aagcgactga tcttttttct ggcgaggatg aatttggcta ccataatacc tttatgaatt
     3061 ttactaaaca atcccatgat attgaactgg gtatcacaaa gactaacacc gaagtttcaa
     3121 atcaagctaa tctttccaat agcagttcat cagctattga acaagaaatt acaaaagttc
     3181 aacaacaaat tggagaatat caagagttga gagatgctat cataaataac agagcacgct
     3241 taccaactgg caatccgcac cagtcaattt tgaatcgtta tcttgtagcc tcacaaggac
     3301 aaacacaagg aactgcagag gagccatttt tatctcaaat taatcaaagt attgcaggtc
     3361 ttgaatcatc tatcgcaagc ctcaaaattc agcaagctgg tatcggaagt gtagcaactt
     3421 atgataacag tttagcaacc aaaattgaag tactccgcac tcagttttta cagacagcct
     3481 cacagcaaca actaactgtg gagaatcaat taacagaatt aaaagtacaa ctagatcaag
     3541 ccacacagcg tttggaaaac aataccttaa cctccccaag taaaggtatc gttcatctga
     3601 acagcgaatt tgaaggtaaa aatagaattc caactggtac agaaattgct caaatattcc
     3661 ctgtcatcac agatacaaga gaagtactaa tcacttacta cgtatcttct gactatctac
     3721 ctctactaga taaaggacaa actgtaagat taaaactgga gaagattgga aatcacggca
     3781 ccaccatcat cggccaactt cagacaattg atcaaactcc taccagaaca gagcaaggaa
     3841 atctctttaa attaaccgct cttgcaaaac tatctaacga ggatagtaaa ctcatccaat
     3901 atggcttaca aggtcgcgtc actagtgtaa ctacaaagaa aacatatttt gattatttca
     3961 aagataaaat tttaacccat tctgattaat tttcagataa cactctataa ctatttatta
     4021 tcttatcaaa aaggagaatc ataacatgga taagaaacaa aacctaactt catttcaaga
     4081 actaacaact accgaactca accaaattac aggtggagga ttgtgggaag atttattata
     4141 taacattaat agatatgctc attacatcac ataagaactt catcatccaa tacaactata
     4201 aaaaaataag accgagaaac aagtactctc ggtcttattt ttcatcattc tgtatgtatc
     4261 acagtaagta cctgacgaaa gacttgattt tgacaggtgg tatttagact ggtattagga
     4321 tggctttcca caatcttcat gacggtatag agaccaactc ctctctcctc ccctttagaa
     4381 ctggctccaa aggagaagat ttcagaaata tcgatgccct cttctttgat ggagttttcg
     4441 atgataaagg tctcctgtgc tccatttttt aaaaaggcga ttgaaacatg aggttgacta
     4501 gcttccacac tggcttcaat agcattgtca caaaggatag acacaatggt tagaaaatca
     4561 agtagactca tcccctcgac ctgaatctcc tcaggaactt cgacattaaa gacaatgttc
     4621 ttatctctgg cttttaaaaa tttccctgct agaagacttt tgagggcttt atcacgaata
     4681 tttaccaatc tgcccaggtc atatttattg ttctgcaatt tctgactgga atcctttaag
     4741 acggagccat agacctcttt tatctgctcc atatcctcct cttcaatgcc cagacgtaag
     4801 ctagtcaaga ggttggtata atcatgacga aagctccgta cttccttgta aagctcctct
     4861 atatgccgac tatagcgttc catatctcta tagcgcaggg cctgctcttg ttccaatctc
     4921 tcatagagtt tttccttcaa ataggtatcc aatttcttga taacccccat aaaaaagagt
     4981 aggtaaaaga ctaggatgag atggcgaaca gtctttgatt gaatactttg ttcatattca
     5041 aaaaaagaca gactttccat gactagatag tagccaccca ttatccagtt aatctgagtc
     5101 agggactttt gaaaggcttt atcgagaatc tcctttctca agctagtaaa atcgtagtcc
     5161 aaccatttca aaaaagctag agaaatgaag aaattgaaaa ttattataca taacccagta
     5221 aatgagtagc catcatatac ttgcccttgt cccaaaaatg gaagcacaaa ataggagact
     5281 cctctataaa agagattcac caatatcatt ggaaagagac cataaaagaa aaggagtttt
     5341 ttaggaagcc ctctcaataa taagaaagat aagcctatgc cgtacaaggg ttccataaaa
     5401 taagataggt aaacatttcc tactatatag ctaatcatca caaaaacaaa ggccaacagt
     5461 atcttaaaaa gaaaggcctt aaaaatcctc tcgaaagtaa gatcaattcc atccacctta
     5521 aagaagatga caatttctag tccattagta acaagtgtat acaacaatat ccaagcaatg
     5581 ttcataaatt ctcctagctc agtgtaattt attgatggcc tcagacactt ccctgacctt
     5641 ataacgggcg attagacaac ttccaccatt gggaaagaaa agcagttttt ctttcttatc
     5701 caaatgcacc acatttgcag gattgatgag aaaagagcgg tggcactgca agagacgggg
     5761 ctcctgcttg aaaacctcct ctaaactcgc tgtaaattcc agcctgtctg tcttggtata
     5821 gagaataaca cgatgggctc tgggcgacgt ttcgagatag taaacctctt taaaaggata
     5881 ctgaaattgg gcaaattttg atttaaagta aaagcaatct tccgccagac ttttactatc
     5941 ttgactattg gcatagagga gggctgtctc gatccgagat tcaaactcct ctgctgacaa
     6001 ggccttatca atgtagtcca aagcagacac ttggtagcga aaagacaggg gcataaactc
     6061 cgagtgagtc gtcacaaaga caatcagggc ataaggatcc cgatcccgaa tctttctagc
     6121 cacttccagt cccttcatct cttcatttcg aatctcaata tccaaaaaga atagctgatg
     6181 ggcccccttc tcatgcactt cagccagcag ttggtccggc ttgccaaata cctcaaaaga
     6241 gctaggaatg atatgatgtg ctttcaaaag tttctcaatc gtcgtttcaa ttctagtctg
     6301 ttgggaaaaa tcatcctcta aaacaaatat tctcatcttc ttactctccc tctttcaacc
     6361 atttttgacg aatttctcta tagcgacgtc tggcatactt gacagcgtat tgaccttctt
     6421 ctccgagaaa aaggattctt tcttgaaaat caatcgattt taatttatca agattaacca
     6481 aacaatttcg atgacatctc atcaaggttt ccccacattg gttctcaaga ttacttaaat
     6541 tttgaagcat attaaaacta gcttcttctg taacaatctg tacggtatgg gctttagttg
     6601 gatgtgtttg gatatagtag atatcgtcga tgtttacttt atagactgtt ttctgcgtct
     6661 gaataatcat atatttcatt ggattctcct cctaagaaaa gaataacaga aaaggtctag
     6721 cccaagcaca cccaatccta aacagtcttt gaaaactcct aaaaggatta ttttctacaa
     6781 catcatgatg agcttacaac tattttatca taaaattcac tcagcgcaat tcaagacatt
     6841 tcaatgacaa ttaaagattt gaataaaaaa aaagaattaa aagtgataaa ctaacagtat
     6901 caaaacacag ttgccagaag taagactggc acccagatta aaggaggcat tcccatgaca
     6961 gatacagacc ccatcaaaag agctcatact ttgattactg acttaaacaa agcctaccaa
     7021 gcatgcaaac aggcaagcgc tgacgacgtc cgctttcagg agcaattaaa ctctattctt
     7081 ggttttctag ccaaggctga aacagtggat aatcgattct tgattgaact agaaaaattt
     7141 taccagactt ccagtcttct catgggactc agcgctcttg atccagatgc tccaactcgc
     7201 gccgcttggc gggcctatga ccgcttccac tttgaccaag tcaagaccaa gttaatactc
     7261 aatgaaaatc aaagagcaaa ctaggaagct agccgcaagc tgtacttgag tacggtaaga
     7321 cgacgctgac gtggtttgaa gagattttcg aagagtataa gtctctacgg accaaccatt
     7381 atcctgtagt aacaaaaaag aagttgagac agactgaact caacttcttt tttagtgtcg
     7441 tatcagcaat gttagtcctg catctgacgt tttacctgat aaggcaaata caagactagt
     7501 aaaaccaaac cagctcctag taaggctaga agggctagtt tttcttggaa ggtaatcaac
     7561 ccaacaacta attccacaag taaaacaaaa ctggtcaatc ctcgaactac ctcctgtaag
     7621 cctttttcct tttgcccctt gtccagcgga aagagttggg tcaaatactg gtagtcaaag
     7681 gcatgataga gggccagcaa ctggaagagc aagaggtagt taaagagaac taccactgct
     7741 gtcgcaatcc aagcttgctc gataaaaacc tgcgccagta cggaaagtaa gagaagacga
     7801 agactgagag caaagaggtc gccatttcgc agataagaac gcagatagag attttgccaa
     7861 atctttccag acaccttctg aacagccttt aagataaagt ccagataggc acgacgtttg
     7921 acactgtttg aaattccctt tacctgcgta aagagggcaa agaaacgaag caagacttgc
     7981 ttacgcttgc tttcttggga aatgacatag tcccagtcca gcccagtttc agtgaaaaat
     8041 ttgctggcct tttgacgaaa gtggaaatat tttcctaccc ccaataaaag cacatagagc
     8101 agaaaaactg gcaagccata acccattgct aaaaataaag gcgcaaataa cagcaagaaa
     8161 agggtctgta caaagagcca aaagactagg gaaatgccag tttgacgctt gagatggagc
     8221 ttgatttcct cttctccaac taagagaaag agcttgtctg gagcctccat ataggtggca
     8281 attcctcccc aaagtaaaag taaaacagac gtaattccta caaacaaaag gataggccaa
     8341 tgattttcag gaaaatgttg taagagttga ctgtactggt aggctagaaa gcccaacagg
     8401 acaagcagga acaagacaaa gtggtcgttg agcacatagc gcagataacc aaggcactcc
     8461 ttacgaaagg cctgctttct ctttaaaaac aagtctttca tagatcctcc tctttggtca
     8521 gagccaagta aatatcattc aaactagcct caggcatatc aaaggcttca cgtagttgca
     8581 ggagattgcc tttggcacgc acctctccct tgtgaagaat gacaaaggca tcacacatct
     8641 tctccgccga atccagcacg tgggtactca tgagaataga cttgcccttt tgcttctcca
     8701 cttccaaaag ctgaatcaaa tcagaaatag ccagcggatc aagaccaagg aaaggctcat
     8761 ccacgatgaa aagacttgga tccaccacaa aagcacagat aatcatgacc ttctgcttca
     8821 tcccttttga aaaatgaaca gggaaccagt ctaatttctg ttccaaacgg aacattttta
     8881 acaagggctc tactcgttcg aaagccactt tttgctcaat accgtaagcc atagcaaccg
     8941 tttcgatatg ctctctgagg gtcaattcct catacagact aggcgtctca ggaatgtagc
     9001 caatctgctt gcggtagcta gtcgcatctc cttgcagagt caggccattg atattgatgg
     9061 agccactata aggtgccaac agaccgataa tctcattgat cgtcgttgat ttcccagcac
     9121 cattgagacc aatcaaaccg accaactgcc cactttcaac agtaaaggac acatctttca
     9181 aaacagggac atgaacatag ccacctgtca ggtttttaat ttctaacata ttttctccaa
     9241 atctggtata atgtagctat attatatcaa aattcagtac agtagaggta gattttatgt
     9301 cagattgcat tttttgtaaa atcatcgcag gggaaattcc tgcttcaaaa gtatatgaag
     9361 atgagcaggt ccttgccttt cttgatatct ctcaagtaac actaggacac accttggtcg
     9421 tgccaaaaga acactatcgc aatcttttgg agatggatgc tacgagcgcc agccaactct
     9481 ttgcccaagt accaaaagta gctcaaaaag tcatgaaagt cactaaggct gctggtatga
     9541 atatcatttc caactgtgaa gaagtcgctg gtcaaacagt ttttcatact cacgttcacc
     9601 ttgtacctcg ctacagtgct gacgatgacc tcaagattga ttttatcgcc cacgaaccag
     9661 actttgacaa acttgctcaa gtcgctgaaa ccatcaaaaa cgcttaagga gttgctatga
     9721 aattatccaa cctactgcta tttgcaggag ctgcagccgg aagttatctg gtcacaaaaa
     9781 atcgccaaac catcacagat gaagtcttga ataccactga ccgcgttcaa gctatcaagg
     9841 acgatgtgga tattatccaa aacagcctgc aaatcattga ccagcaaaaa gaacttatca
     9901 aggaatacca agaagacttg acttacaagt ttaaggtctt ggaaaaggat atccagacta
     9961 gactagctgt gataaaagaa atgcagggaa ctgaagataa gtaaaaagag ccccccggct
    10021 cttttttaaa acgtaaacaa gttatagtga attgaattta gaatagcaca tcatagtttc
    10081 taaagcattg ttagagatta ctttaaaatc ctcttatcaa tttgttcata ttctatttca
    10141 atctactata tatatcccat caactatgca tcataattta ggtaactcat actcaataaa
    10201 aatcaaaaag caaactagaa agctaggcac agactgctca aaacaccgtt ttaaggttgt
    10261 ggatagaact gacgaagtca gctcaaaaca ctgttttgag gttgtagata cgactgacga
    10321 agtcagctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca gtaaccatac
    10381 ccatgacaag ccgacgctga cgtggtttga agaaattttt gaagagtatc attcaccatt
    10441 tcacaactaa atcgaagact ttctgccgta atgaaaacac ctgaaacagc ttggtttcgg
    10501 ctgtccggaa actttaagac ttaggttcaa agtttaggta tggaacttcg aaggaggtcg
    10561 ctaccgtccg tcattactta ggaaagtctt aaaaaatcgg ctctataaag taaaaagagc
    10621 ccgacagctc tttttgttta tattcaatga aaatcaaaaa gcaaactagg aaactagcca
    10681 cgggctgctc aaaacactgt tttgaggttg tagatacgac aagccgacgc tgacgtggtt
    10741 tgaagaaatt tttgaagagt attattctcc atcaaaggca tctttaatat ggtcaaagaa
    10801 gccttttttc tttggattta ctttcaagtc accagcagcc gcgaattctt tcaaggctac
    10861 tttttggcgg tcgttcaagc ctgtcggtgt tacgacatta acagtaacgt attggtcacc
    10921 aactgcaccg ccacgaaggc tcggtgcccc cttactacgt aggcggaatt tcttaccagt
    10981 ctgagttccc tctggaataa ccaattcaac atcaccgtga acagttggaa tatctactgt
    11041 atcaccaaga gccgcttgga caaagttgag gttgagattg tagaagatag tcgttccttc
    11101 acgttcaaac ttgtcgctag cttctacaga aactactaca tacaagtcac cataaggtcc
    11161 accgttaaag cctgcttcac cttgaccagc gaggcgaatt tgttgacctg tttccacacc
    11221 agcagggatt ttcacatgta cgctatgagc ttgtttctca tgacctgttc catgacaggt
    11281 tgtacatgga tatttgattt cttttcctcg accgtgacag acatcacagg ttacttggcg
    11341 acgcatcata ccaagaggag tctgcgtatc gacgttaatg acaccagcgc catgacagcg
    11401 tccacaagtg actggacttg tccctggctt agcaccagag ccattacatg tacgacagcc
    11461 agcttcacga tgatacttaa cttccttctc agttccgaag atagcttctt caaaggtcaa
    11521 attgacacga tactggagat catctccttg gcgaggagcg tttggattgc gcgaagaacc
    11581 gcctccgccg aagaaacttg agaaaatatc ctcaaaacca ccgaaaccac ctgccccatt
    11641 gaaaccgccg aaaccaccag ctccaccaaa accaccattg gcgcctgcag caccatactg
    11701 gtcataggca gcacgttttt ggtcgtcact caaagtctca taggcttctt gaacttcctt
    11761 gtacttgtcc tcagcaccag gctccttgtt gatatctggg tgatattttt tggaaagctt
    11821 acgataagcc tttttgattt cgtctgccga agcgtttttg gataccccca gacgatcata
    11881 aaattcagta ttgttcataa ttcaagatac aaagggcgtc aaacggacac agccatctag
    11941 gagttttgac gacggacgct tacgtcctag aaaaaactat cttttgggca cagtccgtag
    12001 cccgtgttca gttacgaaca cccttattcc tttctattga tgttctgaat cgaaccacca
    12061 tttaggtcgg gttcaattcc tttcttttat atttagtaag aaattctgaa acccgtgttc
    12121 agttacgaac actctttgtt cccttctatt gatgagacaa aacccaaaca aatgagattc
    12181 cgtccctttt tatcgaaaaa cagaggctgg gttgcaacct ctgcaaataa gtaaattaac
    12241 tttattttga ttttaaatat cctataagta cagaaatatt tatatatttt tgtctcttct
    12301 tagtatttgc ctatataatt ccaattgatc ataagaaata caactactgt ccaaatcata
    12361 ccaattatga acggtattac aaatttatat gtttgtattt ctaatgatat catagctggt
    12421 accatcgccg atacaaatgc agacaacaat actgaggtaa caaaattcct taccgcttca
    12481 tcatttttga tacaactatc atgttcagct aatataattt ctctatatct agctaaatat
    12541 tctattggaa tattatcaat aaaatctttt gatgttctat agttatcagc ttgattacaa
    12601 aaatcattat aaacttttcg tgtatttttt agatactctt catccaatac actcatctta
    12661 cttttccgta aactctccgt ctacgacgtc atcgcctgcg ttccctgttg cttgtgcgcc
    12721 ttctgctcct tcttgagctt gttgcgctgc tgcggcttgt tcgtagagtt taacagcaag
    12781 tccttgagct ttttcgttca atgcttcaag ttttgttttc atgtcgtcca agttgttgtc
    12841 ttcttgagct ttcttaaggt catcaagggc agcttgggca gcgtcacgtt ctgcgtcgaa
    12901 gcctttacct tcagtttcct tgattgtctt ttcagtcgca aagattgctt ggtctacttc
    12961 attacgaagg tctacttctt ctttacgttt cttatcggct tcagcgtttg cttctgcatc
    13021 tttcatcatg cggtcgattt cttcgtcagt caaacctgag ttcgattgga tgacaatagt
    13081 ttgttctttt tgagttccaa ggtctttggc cttaacagac acgataccgt tcttgtcgat
    13141 gtcaaatgtt acttcgattt gaggaattcc acgaggtgca gctgggatat cagtcaattg
    13201 gaagcgtcca agagtcttgt tatctgctgc cattgggcgt tcaccttgaa gaacgtggat
    13261 atcaacggct ggttggttgt ctgctgctgt tgagaagact tgtgatttag atgttgggat
    13321 tgtagtgttg cgatcgataa gttttgtaaa tactccaccc attgtttcga taccaagtga
    13381 caatggcgtt acatcaagaa ggacaacgtc cttgacatca ccagtaatca caccaccttg
    13441 gatagccgca cccatagcaa ctacttcatc agggtttact gatttgtttg gttctttacc
    13501 agtttcagct ttaacagctt caacaacggc agggatacga gttgaaccac caacaaggat
    13561 aacttcgtcg atttctgaca agctcaaacc tgcatctgaa agggcttgac gaactggaac
    13621 ttttgtacgt tcaacaaggt cacgagtcaa atcgtcaaat ttcgcacgag tcaaagtcat
    13681 ttccaagtga agaggtccag cctcacctgc agtgataaat ggcaagctga tttgtgttga
    13741 agttacacca gaaaggtctt tcttcgcttt ttcagccgca tctttcaaac gttgcattgc
    13801 catcttgtca gtagacaagt cgataccgtt ttctttcttg aattctgcta ccaagtggtc
    13861 aatgattttt tggtcaaagt cgtcaccacc aagtttgttg tcccctgcag ttgacaatac
    13921 gtcgaagaca ccgtcaccca attcaaggat agagacgtcg aatgtaccac caccaaggtc
    13981 aaataccaag attttttctt ctttgtcagt cttgtccaaa ccataagcaa gagctgctgc
    14041 agttggttcg ttaacaatac gttctacttc aagaccagca attttaccag cgtcttttgt
    14101 tgcttgacgt tgagcgtcgt tgaagtaagc cggaactgtg ataacagctt tggttacttt
    14161 ctcaccaagg tagtcttcag cgtagccttt caagtattga aggatcatag ctgagatttc
    14221 ttgtggagtg tattcttttc catttgcaga aactttttca gaagttccca tcttagattt
    14281 gatagagata actgtatctg ggtttgtaac tgcttgacgt tttgcagcat caccaacgat
    14341 gatttctccg tttttgaatg agactacaga tggagttgtg cggtttcctt ctgggtttgc
    14401 gatgattttg ctttcagttc cttcaagaac tgcaactgct gagtttgttg tacctaagtc
    14461 aataccgata attttagaca tgtgtttttc tccttgttag ttaattttct atttttcttt
    14521 ttgatactct tcttaagtgg cgacgccgtc agagcttgac ttcgtcagtc tcttttacta
    14581 aactttgagc ctaaggtctc aaaatttgcg caaatagcgc cacggcgaag agtatcgtct
    14641 ttggttcgct tcgctcacta ttacaaagca aaacatattt tatctttctt catagtttat
    14701 tgtcgtttcg gacaagtttt ctattatgta aattgcgaca cgaggagtcg aaatcgattt
    14761 tatttcgacg acgagttagt aaggaagcta ggcaaacgcc atagcaattg ccgttttctg
    14821 acgagttgct ttagctaccg tcagaattgc cgaatcgaac acgccctaag ctctgagtaa
    14881 aaaagataga ttttcttgtg ttcatcgaac acttcgtcaa tctcctattt ttactgcgag
    14941 ctttttacgg gctttgtatc ttagttatac accactacca ttgctgggcg taggatgcgg
    15001 tcatggagtt tgtagccttt ttgaaagact tgggcgatgg tatctactgg gtgttcatcg
    15061 tctgctggga gagtttggat ggccatatgg tagttatggt caaattcgcc atctgctgcg
    15121 atttcttcaa ttccttcttc tttcaaagcg tgaatcaagc tttcttgcac catccccaag
    15181 cccttcttca catcatctgt caaaccttca actgcaagtg cacgctcaag gttgtcaaga
    15241 gatggtaaga ttgcttttgc caagtcctgg ctacgataac gttgcaagtt ttgacgttct
    15301 tcattggcac ggcgttggat attttgcatt tctgcatgag cgcgaagata tttgttttcg
    15361 aactcatctg cacgttcatt tgccaagtcc aactcagact tttcaggagt tgtttcttca
    15421 gctgtttcca caacttcctc ttcttgaact tcttctactt cttcattttt tatatcttgg
    15481 gccatgttcg cctcctttaa tgatttcaat cttaatgtac ttcgtaatga ttactgctga
    15541 ggtagcggta aaaatctgtc aacttcatgg tcaaaacacg gttgaccaca ttgatttgat
    15601 tgattagctg ttggtaatcc agattaactg gaccgataat ggctagaatt ccaactcccc
    15661 gataaggaat gaggaactta ctactaatca ccgctaggtc agctaaacag gactcttgac
    15721 cgtctgcaac acgaacattt tgcatctgat cctcacgcaa cccctcacga atctccaagg
    15781 ccaccttttg cggttggtca aagaactgat aggctgctag attggcaaaa ttcaagagat
    15841 tgaccttgcc cgccatcaca atgttttcgt tgaacatttc cttaaagatg tgttcaaaga
    15901 gatcgatgac attatccgtt gttgtaaagt aacgctggat aatctgcgga atctccgtcc
    15961 gaatcttgta gtgaatatct aaaacggtgt gaccgaggaa acgttcctga atgatgctct
    16021 tcagtttcag caaatcctcc tgcaagaagt tccttggaat cagaaactga ctagtaaccg
    16081 ttcgcgactc gtctagggta aataccgcca aggctgtatg ttgccccaaa acaacgatat
    16141 caaaggctgt caaacgttgc ctgctcggct caacatccag tgccactacc gtacagccac
    16201 tcaggtctgt tagcaagtta gcagcctctt gcagaatatc ctccaatttg aagaattcct
    16261 gatcaaaggc tttgacaatc tcatatacct cattttcagc cagtcggtca aaatccagtg
    16321 agtgtttcac atagtactga aaaccagcaa cacttggcat ccgaccgctt gaagtatgag
    16381 ccttctcaag caacccttgt ttttctagtt ccgccatgtc attacgaatg gttgcactgc
    16441 tagagttaat agactcttgc aaggcttttg atccgacagg ttcgtgcgtt ttggtaaaga
    16501 tgtcaataat cagatttaaa atatcctgct gacgctctgt aaccatctca tcactcctct
    16561 ctgtctgatc aattagcact caatgcatcc aagtgctaac ttatgattct attatacacc
    16621 cttagaagag aatgtcaaga caaaaactca aaaaattagc actcttttat aaagagtgct
    16681 aaaaatcaat ctgaagacct agaaccttgc tattcatcta ctcggtattt cctttttagt
    16741 ctgaaataac catgaattag ataagaaatc agaaaagcat ataaaacaaa aataagaaag
    16801 aaagacatag aaagatcctc tctaaacaaa ctcatacaaa caacaagacc acctaagaaa
    16861 gtagctatac aggaacgaag tctagatcgc ataacttccc atttgagccc cttactcata
    16921 tagacttgat cctctggaag taaatcagaa gacgatttac gaagaatcga acaagaacct
    16981 gctcctatca attcccaacc tctatctcta aaatcttgca gttcacgctt atgctcttta
    17041 agaaatctag aatcatagat acgatagata acatcgtccg gttgaccttg ctcaaaatag
    17101 aacaaaccaa aacgactagt tctatacctc caacctttca aatgcatctc atgtaaatat
    17161 tcttctttct tgtccaaatc aacaatggtg aaaatccgaa attctactct gctattcatt
    17221 gtcttacccc aaaattagaa aacatgccta gcgttattta ttagataatt ctttccactt
    17281 ttgactcaat ctccaaaaaa tataagaaat ctgaatcgca aaaactatca ataaaaccca
    17341 atctattatg aaaatcaaaa acacttccca actgaaagaa ctacctccag tgacaaactt
    17401 tgagaaaaac ggtagtagag ctaaaaagag aagcaaaata ggaagcatcc gcattgttaa
    17461 aatccttttg gcataaaaaa atctttattt aaacgaaaat attatggcaa aatttacgcc
    17521 agtttttgaa cggctgatgt agatatttta tactttcaaa atgtttaaat gtgattattt
    17581 atttttgaaa aatagctcac cagcccgact gaaagtgctt atagaatgat aataagtcgc
    17641 ctgccgaaaa cagcgaaaaa tagcagtgtt atgcggagat aatctgacgc gatgcgaaag
    17701 tatattgcat acttattttc aacaatttag cagagtattt ttataagtgt gatataatag
    17761 aagtataatt tgttctgata gtttatttta tggagaagta gatttttaga atgcggagga
    17821 ttcaatatgg ttgagtttat aaagtctaag aaagaaatga gtgaggagga tattaaagca
    17881 aatttcatca ctcctgctat tgtatccaaa ggatggaaaa atggtgagca tatcgcttac
    17941 gaagaatact tcactgatgg tcgaattgaa gttagaggag ataaggctcg tcgtaaagaa
    18001 ggaaaaaaat cagactattc actgtattac caatttggaa ctcgaattgc aattgttgag
    18061 gcaaaggata ataaacacag cgttcgagca ggattacaac aagctattga atatggagag
    18121 attttagatg ttccatttgt ttattcttcg aatggtgatg gctttattga acacgaccgt
    18181 atcacgagag aagaacgtga gctggagtta gacgaattcc ctactcgtga agaattattt
    18241 tctcgtatga cgaaggaaaa aggattgacg tacgaaatta cagaagctat ctcaactcca
    18301 tactatacag acgccttctc aatgaaaacg ccacgctatt atcagcaaat agctatcaac
    18361 cgtactattg aaacagttgc cagaggacaa aaacgagtaa tgtttgtgat ggcaacagga
    18421 acggggaaaa cgttcatggc ttttcaaatt attcatcgcc ttcgaaaagc tggtttggct
    18481 aaacgagttt tattcttagc ggatagaaac atcttagtag accaaacgat ggctgaagac
    18541 tttaagccat tcgaaaaggt aatgacgaaa attacaccaa aacttttgac tgctcctgaa
    18601 aaattaaatt cttttgaaat ttatctaggg ctttatcagc aactaactgg tgaagatgga
    18661 actgaaacac attatcaaaa atttgataaa gacttctttg atttaatcgt aattgatgaa
    18721 gcgcaccgtg gttcagctaa ggaaaacagt aactggcgta agataattga ttatttcagt
    18781 tctgcgacac agattgggat gaccgctact cctaaagaaa ccaagaatgc ttccaatacg
    18841 gaatactttg gtgagccaat ctatacttat agtttaaaac agggaatcga ggatggtttt
    18901 ttggctccat atcgtgttat gagggttaat ttagatgtgg atgtggatgg ttatcgtcca
    18961 gaaactggaa aagttgatac taacggacaa ttaatagaag ataggtacta cggcaggaaa
    19021 gattttgata aaaccattgt cattgatgat agaacgcaaa gagttgccaa gtttgtttct
    19081 gattatatga agcaaaacaa tgcacgattt gataaaacaa ttgttttttg tgttgatatt
    19141 gaccatgccg agcgaatgcg tgctgcactt gtaaaagaga atctagactt agtccaagaa
    19201 gactatcgtt atgtcatgca agtaactggt gacaacgctg aaggaaaagc tcaactggat
    19261 aactttatgg atgtcaattc taattttccc gctatggtaa caacgtctaa attattaacg
    19321 acaggagtta atgctaaaac atgtcgtttg attgttttag actctaatat ccaatccatg
    19381 actgaattta aacaaattat tggtcgtggc acacgtcttt atcctcaaaa ggggaaagaa
    19441 ttttttacga ttattgattt tcgaaatgtt accaatttgt ttgctgaccc tgattttgat
    19501 ggtgagccag tgaaggtgct ggaaacaggt gcgaaaacag tcagtggttc cacgcccggt
    19561 ttcgtagatg aggaaggtga cccagtagaa aaatatatcg ttacagacaa gcaggttacc
    19621 attcttaatt ctactgttca agtattggat gaaaacggga aactgattac cgaaagcctg
    19681 accgactaca ctcggaagaa tatcttaggt agctacgcca ctttgaacga ttttatcaca
    19741 gtttggcata cggcggataa aaagaagctt atcttagacg aactttataa aaaaggagtt
    19801 tatctagatg ctattcgaga gtcggaggga atatcagaac aagaaatcga tgattttgat
    19861 ttactcctaa aacttgccta tggtcaaaaa gaattaacca aaacggaacg tatcaataag
    19921 ctcaaacaaa gcggatattt atataaatat agtgaggaag cgcgtgctgt tttggaaatt
    19981 ttactgaaca aatacatgga taaaggtatt ggagaactcg aaagcattga aacattaaaa
    20041 cttccagaat ttcagatata tggtggaacc ttcaaaatca tcaatactta ttttggagat
    20101 aaaaaacgat atttacaagc aattaaagaa ttggagcaag agctatttac agtagcttaa
    20161 tgaaaggaaa gtatgtcaat tacatcattt gtaaaaagaa ttcaagatat cactcgaaac
    20221 gatgctggtg ttaatggtga tgctcaacgt attgagcaaa tgtcttggtt attattctta
    20281 aaaatttatg atagccgtga aatggtttgg gaattagaag aagacgagta tgagtcaatt
    20341 atcccagagg aattaaaatg gcgaaattgg gctcatgctc aaaatgggga acgggtattg
    20401 acaggcgatg aattacttga ttttgtcaat aacaagttat tcaaagagtt gaaagagctt
    20461 gaaataactt caattatgcc tattcgaaaa acgattgtta aatcagcttt tgaagatgcg
    20521 aacaactata tgaaaaatgg cgtcttgtta cgccaagtca tcaatgttat tgatgaagtt
    20581 gatttcaata gccctgaaga tcgtcattcg tttaatgata tttacgaaaa aattcttaaa
    20641 gatattcaaa atgctgggaa ctcaggagaa ttttatacgc cacgtgcagc gactgatttt
    20701 attgccgaag ttcttaaccc aaaacttgga gaatcaatgg cagaccttgc ttgcggaaca
    20761 ggaggcttct tgacttcgac tctgaaccgt ttaagtagtc aacgtaaaac tagtgaagat
    20821 accaaaaaat ataatacagc tgtttttggt attgaaaaga aagcatttcc tcatctttta
    20881 gcagttacaa atctgtttct tcacgaaatt gatgacccta aaattgttca tggaaatact
    20941 ttggagaaaa atgttcgtga atatacggat gatgaaaaat ttgacattat tatgatgaat
    21001 ccaccttttg gagggtcaga attagaaaca ataaaaaata actttccagc agaattacgg
    21061 agttctgaaa cagctgattt atttatggct gtcattatgt atcgtttgaa agaaaatggt
    21121 cgtgttggag ttattttacc tgatggtttt ctatttggtg aaggtgtaaa aactcgcttg
    21181 aaacaaaaac tggtagatga gttcaacttg catacgatta ttaggttgcc tcatagtgtc
    21241 tttgcaccgt atacaggaat ccatacgaac attcttttct ttgataaaac aaagaaaaca
    21301 gaagaaactt ggttttatcg tttagatatg ccagatggtt ataaaaattt ctcgaaaact
    21361 aagccgatga agtcagaaca cttcaatcct gttcgtgact ggtgggaaaa tcgtgaagag
    21421 attctggaag gtaagttcta caaatctaaa tcatttacac ctagtgaatt ggctgagttg
    21481 aattataatt tagaccagtg tggctttcca aaagaggaag aggaaatctt aaatcccttt
    21541 gagttgattc agaattatca agcggaaaga gcaactttaa atcataagat tgataatgta
    21601 ttagctgata ttttgcagtt gttggaggac aaataatgac accagaacaa cttaaagcaa
    21661 gtattctcca aagagcgatg gaagggaaat tagtgccgca aaatcccaat gacgaacctg
    21721 caagtgaatt attaaagaga attaaagctg aaaaagaaaa acttatcagt gaaggaaaaa
    21781 tcaaacgaga taaaaaggaa actgagatat ttcgtggtga tgatgggaaa cattatggga
    21841 agtttgctga tggaagtact caagaaattg atgttcctta tgatattcct gatacttggg
    21901 agtgggtgag gataaaatca atttattgga attttgggca aaataagcca gagaaatcct
    21961 ttaggtatat agatacgtct agtattgata gaaaaaagaa cataatcaac tacaaaaatc
    22021 tacaatatct ttcacctgaa caagcgcctt cccgtgctag aaaattagtt tcgcagaata
    22081 gtgtcttatt ttcaacagtt agaccatatc taaaaaatat tgctgtagtt agagaactta
    22141 aagagtattt gatagctagt acagcattta ttgttttgga tactttact
//
LOCUS       DAVKBK010000026        22101 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVKBK010000026 DAVKBK010000000
VERSION     DAVKBK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.026"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            134..433
                     /locus_tag="VWX69_001164"
                     /pseudo
     CDS             134..433
                     /locus_tag="VWX69_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            516..2537
                     /locus_tag="VWX69_001165"
                     /pseudo
     CDS             516..2537
                     /locus_tag="VWX69_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            2539..3180
                     /locus_tag="VWX69_001166"
     CDS             2539..3180
                     /locus_tag="VWX69_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192519.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3284..4636
                     /locus_tag="VWX69_001167"
     CDS             3284..4636
                     /locus_tag="VWX69_001167"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU9192520.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4640..5698
                     /locus_tag="VWX69_001168"
     CDS             4640..5698
                     /locus_tag="VWX69_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU9192521.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5708..6907
                     /gene="divIB"
                     /locus_tag="VWX69_001169"
     CDS             5708..6907
                     /gene="divIB"
                     /locus_tag="VWX69_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU9192522.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEDDKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDLDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            7140..7841
                     /gene="pyrF"
                     /locus_tag="VWX69_001170"
     CDS             7140..7841
                     /gene="pyrF"
                     /locus_tag="VWX69_001170"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU9192523.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            7875..8507
                     /locus_tag="VWX69_001171"
     CDS             7875..8507
                     /locus_tag="VWX69_001171"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU9192524.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            8687..9090
                     /locus_tag="VWX69_001172"
                     /pseudo
     CDS             8687..9090
                     /locus_tag="VWX69_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9186..9950
                     /locus_tag="VWX69_001173"
     CDS             9186..9950
                     /locus_tag="VWX69_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192525.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9950..10702
                     /locus_tag="VWX69_001174"
     CDS             9950..10702
                     /locus_tag="VWX69_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192526.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            10712..11410
                     /locus_tag="VWX69_001175"
     CDS             10712..11410
                     /locus_tag="VWX69_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192527.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11407..12054
                     /locus_tag="VWX69_001176"
     CDS             11407..12054
                     /locus_tag="VWX69_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192528.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12134..12995)
                     /locus_tag="VWX69_001177"
                     /pseudo
     CDS             complement(12134..12995)
                     /locus_tag="VWX69_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(13007..13765)
                     /locus_tag="VWX69_001178"
     CDS             complement(13007..13765)
                     /locus_tag="VWX69_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9192529.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(13766..14443)
                     /locus_tag="VWX69_001179"
     CDS             complement(13766..14443)
                     /locus_tag="VWX69_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9192530.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(14403..15071)
                     /locus_tag="VWX69_001180"
     CDS             complement(14403..15071)
                     /locus_tag="VWX69_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9192531.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGDSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            15297..15443
                     /locus_tag="VWX69_001181"
     CDS             15297..15443
                     /locus_tag="VWX69_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU9192532.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            15571..17061
                     /gene="lysS"
                     /locus_tag="VWX69_001182"
     CDS             15571..17061
                     /gene="lysS"
                     /locus_tag="VWX69_001182"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU9192533.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            17686..18822
                     /gene="lctO"
                     /locus_tag="VWX69_001183"
     CDS             17686..18822
                     /gene="lctO"
                     /locus_tag="VWX69_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU9192534.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDKRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLRLY"
     regulatory      19076..19164
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            19379..20047
                     /locus_tag="VWX69_001184"
     CDS             19379..20047
                     /locus_tag="VWX69_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU9192535.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLIMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            20284..21066
                     /gene="thiM"
                     /locus_tag="VWX69_001185"
     CDS             20284..21066
                     /gene="thiM"
                     /locus_tag="VWX69_001185"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9192536.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPE
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            21068..21697
                     /locus_tag="VWX69_001186"
     CDS             21068..21697
                     /locus_tag="VWX69_001186"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9192537.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      21906..21994
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
BASE COUNT         6769 a         3796 c         4761 g         6775 t
ORIGIN      
        1 attttttcct tgacaacaaa taataaaaat gttattctta tcacataaga aagcggtttc
       61 aataaaagag agaggaggat ttattttgtt gcattgttgc tcaaggtgtg atttttttga
      121 aagaaaaaat aaaatgaaaa cgaaaaaaca tagattactt gctctagctc ttatttcaag
      181 ttttacatta ttgggagctg catcagctgc tgtataatat ccagatggag gagtatggac
      241 atatggagaa ggttcaggag gtggttaggc tttttcaaat tactatcatg gtaaaaaata
      301 tcattattca tccatcgtga gcagatggga tggtcattct gataaaggag aagctcctgc
      361 tggaaaaacc tcctatgcat ggatttggac taaatgggga gaacaagtag cattttactg
      421 tgattatgac taatcgttca ttgatttaaa tcgttcccct tgtaagaaat tacaggggga
      481 attttgttta caaggagtct accaaggagt ctactatgaa gaaactattc atattattat
      541 caactttttt tctcagcttc ttccttgctt ggattattgt cttacgtgcg ccacaatatt
      601 tatatgcaag ctatgattcc gtttctttac ttcgtgtcaa aaaagatact caggaaccga
      661 cgcgtgaggt atttgaacag gaattggaga attttgcaaa ctcagaacag agtttaatag
      721 ctagaagaat tgtagagccg agtaaggatg ggacgactca ctttacttat gcaacttatg
      781 gtcagggaac tttaccaaaa gaattccaag aagctagcca agaaagtcgt gaacgtagtg
      841 atccgctaaa tagttatctc cttttgtcag gctccttgac gaaagaaaag cttgccgata
      901 aattaggaga tttgggttat aaagcaagtg ctgaccgaaa gataccgccc tattttcttg
      961 cttttcgaat attactaaat ccccttattt taattagttt agcaatattt ggcttatctt
     1021 tctttgcttt agtgattatc actcggatta aggaaatgag agcagcaggt ataaaactct
     1081 tttctggtca gactctctta tccatcatgg ggcattcttt atctactgat atcaaatagc
     1141 tccttctatc agccctcctt tccttcctag gtgggggagt cgttcttttt agtcaaggtt
     1201 tgttttatcc tatcttgtta gccacctatg gttttgggat tagtttctat ctgttgtttt
     1261 tattggcgat ttcaatttta ctaatgcttc tttatctaat gagtttgagt tacaaagcat
     1321 tagttcccgt tattaagggg agattacccc ttaaacgcct gatgatttta accctattgt
     1381 gtcagttggt tgctgtcttt acagtaggat acgctgttaa gacaggtttg acgtcttacc
     1441 aacgattgaa agaacttgaa atttcaaaac aagcatggca ggatagagca gactattatc
     1501 aaatttcttt tggcttaggt gatagaggaa aagatacaga aaatcagagc aagtggtatg
     1561 cctttgccaa ggaagcaatc gaagaggaac aagctcttta tgtaaaggat aatctgctcc
     1621 attttgccaa tccacaagga aaaaatgaac agggagagac actggatacc tatagtccag
     1681 atgctaatac gctctatgtt agtcccagtt atttggacaa ggaaaaggtc gtggtagatg
     1741 ctgagaccaa acagaagtta gcccatctcc aaaaaggtga gtttatcctc ttgctcccag
     1801 aacatttgcg ctctcgagaa gcagaactta agaaagtttt tgaagaaaga ttgagttatt
     1861 atggaaaatc tggtgaggag gcaagtgctc ctttggatta tgagatgaaa gcgcacgtta
     1921 gttatctttc aatgggagaa aagcggtttg tttataataa cggtgagaat cccgtatcta
     1981 ctcagtattt gactgatccg attttagtgg tattcacgcc gacttctaca ggtgatagtt
     2041 ttatatcctt atctagttgg tctatcaatg ctggaaaaca actctttatc aaaggatatg
     2101 agagtgggct agaactcttg aagaaagctg gaatttatga gcaagtatcc tatcttaaag
     2161 aaggaagaag tgtttatcta actcgttata atgaagttca aactgaaaca gcaactttaa
     2221 tcttaggagc tattgtgggg atagctagtt ccttattact attttattct gtcaatcttc
     2281 tatatttcga gcaattccgc cgagatatct tgattaaacg aatttcaggt ttacgatttt
     2341 ttgaaacaca tgctcagtat atggttagcc aatttgccag ttttgtattt ggtgctagtc
     2401 tctttatttt aagcagtcga gacttggtga ttggcttgct cactttattg gtctttctag
     2461 ctagtgcagt tttgacgctt taccgtcaag cgcagaaaga atctcgtgtt tctatgacaa
     2521 ttatgaaagg aaaataggat gattgaacta aagaatatat ctaaaaaatt tggaagccgt
     2581 cagctatttt cagatacgaa tcttcatttt gaaggtggga aaatttatgc cttaatcggt
     2641 acaagtggct gtggtaagac aacactcttg aatatgattg gacgattgga gccatatgac
     2701 aaagggcaaa tcatctatga tggcacttct cttaaggaca tcaagccttc tgttttcttt
     2761 agagattact taggatactt atttcaagat tttggcttaa ttgaaagcca aaccgtcaaa
     2821 gagaatctca atctgggttt agttggtaaa aagttgaagg aaaaagagaa aatctctttg
     2881 atgaaacaag ctctaaactg tgtaaacctc tcttatttgg atttgaagca acctatattt
     2941 gagttatcag gaggagaagc acaacgtgtt gcactagcga agataatttt aaaggatccg
     3001 cctttgattc ttgcagatga accaaccgct tccttagacc ccaaaaattc tgaggaatta
     3061 ctttccatcc tagaatcttt aaaaaatccg aatcggacca ttattattgc gacccacaat
     3121 cctctgattt gggagcaagt ggatcaggtc attcgagtta ccgatttatc acatagatga
     3181 tatggtaaga ttcagttaga agaaagagtc acaaacacac tttgtggctt ttttatttcc
     3241 ataaaaatgg taaaatagta ggagtagaaa tggagttcga gacatgaaag taatagatca
     3301 atttaaaaat aagaaagttc ttgttttagg tttggccaag tctggtgaat ctgcggctcg
     3361 tttgttggac aagttaggtg ccattgtgac agtaaatgat gggaaaccat tcgaggacaa
     3421 tccagctgcc caatgtttgc tggaagaagg gatcaaggtc attacaggtg gccatccttt
     3481 ggaactcttg gatgaagagt ttgccctcat ggtaaaaaat ccaggtatcc cctacagcaa
     3541 tcccatgatt gaaaaggctt tggccaaggg aattccagtc ttgactgagg tggaattggc
     3601 ttatttgatt tcagaagcac cgattattgg tatcacagga tcgaacggta agacaaccac
     3661 aacgactatg attggggaag ttttgactgc tgctgggcaa catggtcttt tatcagggaa
     3721 tatcggctat cctgccagtc aggttgctca aatagcatca gataaggaca cgcttgttat
     3781 ggaactttct tctttccaac tcatgggtgt tcaagaattc catccagaga ttgcggttat
     3841 taccaacctc atgccaactc atatcgatta tcatggatta tttgaggaat atgtagcagc
     3901 caagtggaat atccagaaca agatgacagc agctgatttc cttgtcttga actttaatca
     3961 agacttggta aaagacttgg cttccaagac agaagccact gttgtaccat tttcaacact
     4021 tgaaaaggtt gatggagctt atctggaaga tggtcaactc tacttccgtg gtgaagtagt
     4081 catggcagcg aatgaaatcg gtgttccagg tagccacaat gtggaaaatg cccttgcgac
     4141 tattgctgta gccaagcttc gtgatgtgga caatcaaacc atcaaggaaa ctctttcagc
     4201 cttcggtggt gtcaaacacc gtctccagtt tgtggatgac atcaagggtg ttaaattcta
     4261 taacgacagt aaatcaacta atatcttggc tactcaaaaa gccttatcag gatttgacaa
     4321 cagcaaggtc gtcttgattg caggtggttt ggaccgtggc aatgagtttg acgaattggt
     4381 gccagacatt actggactca agaagatggt catcctgggt caatctgcag aacgtgtcaa
     4441 acgggcagca gacaaggctg gtgtcgctta tgtggaggcg acagatattg cagatgcgac
     4501 ccgcaaggcc tatgagcttg cgactcaagg agatgtggtt cttcttagtc ctgccaatgc
     4561 cagctgggat atgtatgcta actttgaagt acgtggcgac ctctttatcg acacagtagc
     4621 ggagttaaaa gaataaaata tgaaaaaaat tgtctttaca ggtgggggga cggttggaca
     4681 cgttaccctc aatcttttgt taatgcccaa gttcatcgaa gatggttggg aagtccacta
     4741 tatcggggac aagcgtggta tcgaacacca agaaatcctt aagtcaggtt tggatgtcac
     4801 tttccactcc attgcgactg ggaaattgcg tcgctatttc tcttggcaaa atatgctgga
     4861 cgtcttcaaa gttggctggg gaatcgtcca atcgctcttt atcatgttgc gacttcgtcc
     4921 acagaccctt ttttcaaagg ggggctttgt ctcagtaccg cctgttatcg cagcgcgtgt
     4981 gtcaggagtg cctgtcttta ttcacgaatc tgacctgtct atgggcttgg ccaataaaat
     5041 cgcctataaa tttgcgacta agatgtattc aacctttgag caagcttcga gtttgtctaa
     5101 ggttgagcat gtgggagcag tgaccaaggt ttcagatcaa aaaaatccag aaccagatga
     5161 attggtggat attcaaaccc actttaatca taaattgccg actgtattgt ttgttggcgg
     5221 ttctgcaggt gctcgtgtct ttaaccaatt ggtgacagac cataagaaag aactaacaga
     5281 gcgctacaat attatcaatc taactggaga ttctagcctg aatgagttga gccaaaatct
     5341 ttttcgtgtt gactatgtga ccgatctcta tcaacccttg ttggaattgg ctgatattgt
     5401 tgtgacacga ggtggtgcca atacgatttt tgagctcttg gcgatagcaa aattgcatgt
     5461 cattgtgccg cttggtcgtg aagctagtcg tggtgaccag attgaaaatg cagcttactt
     5521 tgtaaaaaaa ggctatgcag aagaccttca agaaagcgat ttgaccttgg atagtttgga
     5581 agagaagctt tctcacttac taagtcacaa ggaagattac caagctaaga tgaaagcttc
     5641 taaggaattg aaatctctag cagattttta tcaattgttg aaaaaagatt tatcataagg
     5701 aaagtaaatg tcaaaagata agaaaaatga ggacaaagaa atcctcgaag aattgaaaga
     5761 gttatcagaa tggcagaaac gaaaccaaga atatctaaaa aagaaggctg aagaagaagc
     5821 ggctctagct gaggagaagg aaaaggaaag acaagctcgg atgggagaag aatctgagaa
     5881 gtcagaggac aaacaggacc aggagagtga aacagaccag gaagattcag aatcagctaa
     5941 ggaagagtct gaagaaaaag tagcatcctc agaggatgac aaagagaaag aagagaaaga
     6001 agaaccagag tctaaagaga aggaggaaca ggataaaaag cttgctaaaa aggctacaaa
     6061 ggaaaaacca gccaaagcaa agattcctgg tatccatatc ttgcgagcct tcacgatttt
     6121 atttccaagt ctgcttttat tgattgtctc tgcctacttg ctcagtcctt atgcgaccat
     6181 gaaagatatt cgtgttgagg gaacggtgca aactacagct gatgatattc gacaggcttc
     6241 aggcattcag gattcggatt atacgattaa ccttctgcta gacaaggcaa aatatgaaaa
     6301 gcagattaag tctaactatt gggttgaatc agctcaactt gtctatcaat ttccaactaa
     6361 gttcactatt aaggtcaagg aatatgatat tgtggcctac tatatttctg gtgaaaatca
     6421 ttatcctatt ctttccagtg gtcagcttga gactagttct gtgagcctga acagtttacc
     6481 agaaacttat ttatcagttc tctttaatga tagtgaacaa atcaaggttt ttgtctcaga
     6541 acttgctcaa attagcccag aactcaaggc ggctatccaa aaggtggaat tagccccaag
     6601 caaggtgaca tccgatttaa ttcgattgac tatgaatgat ttggacgaag tcttggttcc
     6661 gctttctgaa atgagcaaga aactgcctta ttatagtaag attaagccac aattgtcaga
     6721 accgagtgtg attgacatgg aagctggaat ttacagttac actgtggcgg ataaattaat
     6781 tatggaagct gaggaaaaag ccaaacaaga ggctaaggaa gctgagaaaa aacaagaaga
     6841 agaacagaaa aaacaagagg aagagagcaa tcgaaaccaa acgacccagc gctcatcgcg
     6901 tcgctaggtt taccttttct cttatagttc tttagtgacc atgtttttac ttgacaagtg
     6961 ctagtagaaa taatagaata gtaaaaaacc tttaaagcag tccagagagg cagctaaggt
     7021 tagacggtga aagggtggag actacccatt tttcgtggaa ccttgctgtt ggcaggttcc
     7081 ttttttcgtg gcttctgttg gccagactct ctcactagta aaggtaaaag gagaaaccta
     7141 tgcgagaaca tcgtccagtc attgctcttg attttcctag ttttgaggcg gtcaaggaat
     7201 ttttagctct tttcccagca gaagaaagcc tttatctcaa ggtagggatg gagctttatt
     7261 acgcagcggg gcctgagatt gtgtcctact taaaaggttt gggtcatagt gtctttttgg
     7321 atctcaaact tcatgacatt cctaatacag tcaagtcagc catgaaggtc ttgtctcagc
     7381 ttggtgtcga tatgactaat gtccatgcgg ctggtggtgt agagatgatg aaggcggcgc
     7441 gtgaaggcct tgggagtcaa gctaaattga tcgctgtaac tcagctcaca tcaacgtcag
     7501 aagctcagat gcaggagttt caaaatatcc aaaccagtct gcaagagtct gtgattcact
     7561 atgccaagaa gacagctgaa gctggcttgg atggtgttgt ttgctcggct caggaagtac
     7621 aagtcatcaa gcaggctacc aatccagatt ttatctgtct gacaccaggg attcgtccag
     7681 ctggtgctgc agttggagat caaaaacgag tcatgacacc tgctgatgcc tatcaaatcg
     7741 gcagtgacta tatcgtagtg ggacgtccca ttacccaagc tgaggatcct gttgcagctt
     7801 atcataccat caaggatgaa tggacacagg actggaatta aagaactaga ttagaaaaat
     7861 aaaaggagaa taccatgaca cttgctaaag atatcgctag ccacctcttg aaaatccaag
     7921 ccgtttacct caaaccagag gaacccttca cttgggcatc tggtatcaag tcaccgattt
     7981 acactgataa tcgtgtgaca ctagcctatc cagaaactcg taccctaatt gaaaatggtt
     8041 ttgtggaagc tatcaaagaa gcctttcctg aagtagaagt gattgcagga actgcaacag
     8101 cagggattcc acacggagcc attattgctg ataagatgga cttgcctttt gcctacatcc
     8161 gtagcaaacc aaaagaccac ggagctggta atcaaatcga aggtcgcgta gctcaaggtc
     8221 aaaaaatggt agtggttgaa gaccttattt caacgggtgg ttcagttctt gaagctgtag
     8281 cagcagccaa gcgagaagga gcagatgtgc ttggagttgt agcgattttc agctaccaat
     8341 tgccaaaagc agataagaac tttgcagatg ctggtgttaa acttgtgacg ctttcaaact
     8401 atagcgagct tatccatcta gcccaagaag aaggttacat cacgccagag ggccttgatc
     8461 ttctaaaacg ctttaaagaa gaccaagaaa attggcaaga aggttaggtc agtaagataa
     8521 agagagatga ggctaccgag cctcttttat cattttattt aaaatatgac aatattttaa
     8581 ataaaatgat tgacaacgct ttcttttgtt gatataatga aaatgtaata tgtatcaaat
     8641 tgatcaatca actatcttgt ttatcacttc ttaggaggac gatgtcatga aaagaagaaa
     8701 aatatattcc ttttttgcgt agttacaatt gcatctagtt tgtttctcct tacagtttta
     8761 gctagacaga ttggagatta tgatttaacg ttgccgcgtt ggggttcgga tacaactagt
     8821 gagcttgaga aagaaaacgc ctctgctgga attaataata atgacagcac tggtggcggt
     8881 aaaaggttaa atacctctat tcgtagcgcc tatagtgggt cagatattac cccggtatat
     8941 tcattggggt ctggctctag gattgtcatg tactataatg gaggtggtga caattatatt
     9001 ggttctggta ctagattagc tatggcgcca caatttggaa atcatgtaag aattcatact
     9061 tcaggttctt ggaatccaga ttcttattaa cttacttgtc agagtaagcc ttagagatgg
     9121 ttgattgtgg gtgtagcatg aaaaaagaat gctacaccct atttttatta taaggaggag
     9181 taaggatgga atttttcatt tgtaatcttg tacgagtcgt tcaatcacct cgattttata
     9241 tgtctttatt tttgaccctt ctttgcatga gtttaggaaa tttccttgct ttcaatggta
     9301 tttataaaat tgaaggttta tcgatttttt ttgccgcttc ttctattcga ggattttcac
     9361 cgattagcct agtagctgca cttatctgta cactgcccta ttctagtcag ataatagagg
     9421 atgctgagag tcattttcta acagcacaat tgtgtcgaat ttctaaaaag aagtatctgg
     9481 ctattgtggg tagtactgta attatttctt cttttctagt cttttttctc ccctatttat
     9541 tattattagg aattaatctt ttagtgactc cttatcagga aatttatatt ggagattata
     9601 gtggtgcctt aaaagaatta tttgattcca atcagtttct ctatagtctt gtaacgactc
     9661 tctggtatgg agtttggggc gctgtgttct ctatttttgg actagctagt gctttgctag
     9721 tgaagaaaaa aataggagct attttcatcc cagttgccta tatgatggtt ggtggtattt
     9781 tttgggctat tttagggcta tcttacttag aacctgtgac aacattagct ttgggatatc
     9841 agaaagatat cagtctttcc ttagttagtg ggcatcttgc ttttatttta tttgttagtt
     9901 gtttggttgt ttatggtaca ttttttctac attcagagga ctacgtataa tgaaacaatt
     9961 tgttcaattt tacaaaaaag attttttatc agtattggtt tattttatat tactgctatc
    10021 ctgtgtttta tctagtacag tatatttatt gcgctgtcgc caatattcaa tccatccaaa
    10081 tgtattagaa tggatcttag ttttacttca agatatgacg actggagtat attgctttcc
    10141 gttcacatat atattgttct ttttttattt gatgaataac tattttaata ggttggagtg
    10201 tcgcattcgt ctgaaatcaa ttaagcactt taccagtttt agtttcaaat tagcagctct
    10261 tagtacgggg atttggacgg cgactttatt tttattgatt tttctaattg catttagtaa
    10321 tggttttagc ttctctttgg agataaagga ggttgatttt ttaagagaat tttatggtat
    10381 aagtattgca aacaatgcta gtttctttat aggatttttt ttctcttata tagcatacta
    10441 tttcttttta tccttactta ctattagcag tttttcttgg tttaaaaaat caaacatgag
    10501 cttagtattt ctgtttactt ttttatttgt agaatcctta ttctggattt atcagttgga
    10561 caatgggata attggattat tgccaatttt tcagtatatg gtaaattcca atccgtatgc
    10621 attgatttat tggcttacat tactatctat cataattcca ttgactgtat tttctgttca
    10681 tagaaactgg aggagagtgt aaaagttgga aatgggaaag ttaagtagtc acatgtggag
    10741 gttgaatcag ataatctata ccaagtactt ttggggttat gttctttttt ggatattgat
    10801 ttgtttagga ttatggtatt ggttagaagg aaatgataga cttgttatag aaattttaaa
    10861 agggcctaat ctgagtcaaa actctttttt agtcttatct atatggttgc ttcattggtt
    10921 tattattcat acattttttc tagcagttgt atatcgtaga agagcatccg atttctttat
    10981 ggaagtgatt cgattttctt ctattaagct ctggattagg tatcagattt ggacctgttt
    11041 tctttatgga ctcattttaa tcatggtaaa agttctagtg attcaattta tgttacagtt
    11101 accaaactgg gatataggag ttttgtttat agttgattct ttgaatgctt gtgtgttagt
    11161 cttgttttgc tttatgttat acgcactagg agcgaatgta caaatgaact ttgcttgcgt
    11221 tagtttcttt ttactcatga ttgtgtttgg tggtctattt gtaggaaatc gaactaatta
    11281 tctattttat attttgaatc gagggaatgg agatatagga cgagatttat ttcttcagtt
    11341 gctattttta gtctttcttt ttaaaagtat tttctatttc actcgtcaaa agaggaggtt
    11401 tatagaatga atgaaataat catattaaaa aatattgagt tgaaattaaa aaaaacatgt
    11461 gtttttcaaa accttaattt tagttgtaaa cagggggaaa ttataggaat tactggtgcg
    11521 aatggctcag ggaaaagtgt attgtttaaa ttaatagctg gtttatatag tccgtcttat
    11581 ggagaagtgt taatcaatgg ggaaaatatt gttcctgaga gaaaaattcc agctaatttg
    11641 ggagctttga ttgaagaacc tggttttata aattattata gtggctttaa gaatttacaa
    11701 tatttggcaa gcatacgagg agtagttggt aatcaggaaa tcaatgatac actgaaaata
    11761 gttggtctat atgagcaaaa agaccagaaa gttaaaactt attcgctagg tatgaggaaa
    11821 aagctaggga ttgctcaagc aattatggag aatccctcta ttcttttact agatgaacct
    11881 atgaatgcct tggataaatc aagtgtagaa aatatgagaa cattgtttag aaagctctct
    11941 agtgaaaaag ggacaacaat tttgattgct agtcatagtg aagaggatat tcgtatctta
    12001 tgtgataaag tatatgcaat agaagataaa gtatgtacac tgtgttcaga ttgaacatct
    12061 tagatagact caggatgtta taggtaaaat cttaaaaagg gattggagct taaaatccag
    12121 tcccttttaa gagttaatgg ccaccttcaa caaccaggtc atctgcttta gcagcgtcac
    12181 cgtaggttgg gtgaagtgtt ttttcatagg ccttgtggaa gaagttttcc ttgcctaatt
    12241 tttcaatatc tttattgatg aagtctagca attcttggtt gcctttttga actgctgccg
    12301 caatggtatc gggatcaccg agggaagtaa ttcctacttc aaatccttta ttttcaagcg
    12361 cccaagctag aacttccgta ttgtcagttg aaaaggcatc tccacgtccg tcaagaagag
    12421 cttggtaaga gtcactgtat tggtcgtatt tttggagttt gatttctgga tgattctttt
    12481 caaaataagt ctcagcagtc gttccttttg tgacaattaa ggttttacct tcaagttgtt
    12541 tgacgtctgt aatgagacca gtcttaggtg atacgacacc cagagaaact ttcatatatg
    12601 gaagggcaaa atcaacttgt ttcttacgtt cgtcagttac tgtaaagtta gcaagagtaa
    12661 tatctacctt gtttgaaatc aagtattccg cacggttggc agcatcgact gaaatgtatt
    12721 taaccttgac accaaggtct ttagctagtt ggttccctag ttcaatatcg tagccttggt
    12781 aagaaccatc attgtcaacg tagccaaacg gttttttatc tccaaacacg gcgattcgca
    12841 gttcaccgcc tttttttgat ttcatcgata gtgcgagctt tggcagttgt ttttccagag
    12901 gatgaaccag cgtttccacc tgagctacaa gcagtgataa agataagggc aaaggcaagt
    12961 gctaaaacag ttaagagtgg tttgaatagt ttcataagaa tctcctttat agatatgagc
    13021 caaattggct aaagtcaaag acgtttaaaa attcctgggc tcgtttggtt tgcggattgg
    13081 taaagaaggc ttgagctgtt ccttcttcag cgattttccc ttggtcgagg aagataatcc
    13141 ggtcagcaat ggcttgggca aactgcattt cgtgggttac taaaatcatg gtacggcctt
    13201 cttgggccaa atcattgata agttccagca cctcacgcac catttctgga tccagcgaag
    13261 cagtcacctc gtcaaaaagg atgatttctg gatgcattag gagggcacgg acaattgcaa
    13321 cacgttgctt ctgtccacca gataattgac gggcaaagct atgttgttta tccagcaaac
    13381 cgacacgatc tagtaattgc aaagcttctt ccgttacttc tttcttgtcc cttccttgag
    13441 ttttgatagg gcctaggatg aggttttgta agacatccag atggggaaag agttcataac
    13501 tttgaaagac catgccaatc ttttggcgaa ctaggtgaaa atttttttta ttttcaacga
    13561 tagactgacc atccagaaaa atatctccac cttgaatact ttctaagccg ttgaggcaac
    13621 gaaggagggt acttttccca caaccagatg gccctaggat gacaacaact tccccttttt
    13681 tgatttctag agaaagtcct tggaggatgg gattgtctcc gaaggatttt tttagttcct
    13741 tgatttctaa gatagtttca gacatttagt ttctccaatg tttttctaag tgagtggata
    13801 gtttggaaat agggtagcaa actgcgaaat ataagactag aatggttcca taaatccaaa
    13861 atgaagcagt tgggatggtc aggcgattgc tatcgatgat ttgttgtcca actttggtca
    13921 cttccacaac cccaatcaaa acaactaatg aagtggtttt aatcatccga gtgacaagat
    13981 tgatagcctg cggtagcagt cttctcaaga cttgtgggat gatgatgtgg tagtaaagtt
    14041 gaacattagt caagccgagt gcctgtccac tttcaaactg atgtttaggg agagaagtga
    14101 tagctccacg taccaagtct cccatttcag ctgttcccca gagggtaaaa acgataatag
    14161 ctgaagtctc acctgagata ttgatattaa agtttcgagc caagccaaag taaacgatga
    14221 agagtagcac cagctggggc atgatacgga taaattccag atacaatcgt gttaaaaatc
    14281 gtatgattct agaatgggag gtcatgatga ttcccatgac tgttccgaac atcatggata
    14341 agaggacaga caggatggat atcccaatcg taacgcccaa tccctgtaag attctcagga
    14401 gattatttcc ttgaaagagt acttggattc ccgaatcctg catggcggag cctcctttct
    14461 atccagctaa agaccagtga gatgggtagc agcatgatca gataagcaac taccaacata
    14521 gctagcgcaa tgtctgtctc atagtagaga ccaatcaaat ccttggcgac gtacatgagg
    14581 tcggccaaag ccactgctga gaaaacagag gtttccttga taaggaaaat gacattggca
    14641 ctaaaggagg ggagtgccac cgctgttgct tgcggaagaa ccacatagta aaagacctgt
    14701 agaggtgtca gaccaatagc gaggccaatc tcctgctggg tttgactgat ggcttccagc
    14761 ccgcttcgga aagattctgc catataggag tctcctaaaa agacaagccc aagcgttgca
    14821 cagacttctg aagataggac aatcccgatt cggggaagac cgaagtagag aaagaagagt
    14881 tgaatcaaaa ggggcgtatt acgtgacaat tcaatgtagg ctgtcgctac ttgcgacaaa
    14941 acaaggattc gataatgtcg gatgatacta acgattaaac cgagcagaaa ggatcccaaa
    15001 attccccaaa ctgcaatatg caaggtcaga aagaatgcct tttgatatag tggtagatat
    15061 tgttcaacaa tggatcaatc caaaaataga acctcccatc tagaaataat acagttattg
    15121 tagcacttaa aatcttcttt ggataatatc tattttttat tgccgttata aggattttta
    15181 tcatagacat aaaatttctg aaatttccaa acaaaatatt ttaaaagttt tgaaaaagag
    15241 ttaagatatt tttgtaatac acaaagtaaa cgcttactta ttaaggagga cattttatgt
    15301 catacaaaac aagcaatgca gaaggtcatg tagatttcat caatacctat gatttggagc
    15361 caatggcgca acaagttatt cctaaagcag catttggcta tatcgctagt ggggcgggag
    15421 atactttcac ttctttccag tgattttagc gtcaggttct ttttagtttt taaagattat
    15481 ccgtgaattt cttgcttatt tatgataaaa tgggagtatc gcaaaaaatg actcatcgta
    15541 ttcaattttg agtaaaacta ggaggatccc atgtctacag aacatatgga agaactaaat
    15601 gaccagcaga tcgttcgccg tgaaaaaatg gctgcgctcc gcgaacaagg aatcgatcct
    15661 ttcggaaaac gttttgaacg tactgcaaat tcacaagaat taaaagataa atataccaac
    15721 ctcgataaag aacaattaca cgataaaaac gaaacagcta ctatcgcagg acgcttggta
    15781 accaaacgtg gtaaaggaaa agttggtttt gcccaccttc aagaccgcga aggccagatt
    15841 cagatctacg ttcgtaagga tgctgtcggt gaagaaaact acgaaatctt caaaaaagca
    15901 gaccttggtg acttccttgg tgtcgaaggt gaagtgatgc gtacggatat gggagaactc
    15961 tctatcaagg caacccacat cacacacttg tctaaggctc ttcgtcctct tcctgagaaa
    16021 ttccatggtt tgacagacgt tgaaacaatt taccgtaaac gttaccttga cttgatttct
    16081 aatcgtgaaa gctttgaacg ctttgtcact cgttcaaaaa tcatctctga aatccgtcgt
    16141 taccttgacc aaaaaggatt ccttgaagtg gaaacacctg ttcttcataa tgaagccggt
    16201 ggtgctgctg cccgtccatt tatcacccac cacaatgccc aaaacattga catggtgctt
    16261 cgtatcgcga ctgagcttca cttaaaacgc cttatcgtgg gtggtatgga acgtgtctat
    16321 gaaattggcc gtatcttccg taacgaagga atggacgcta ctcataaccc tgagttcact
    16381 tctatcgaag tttaccaagc ttatgcagac ttccaagaca tcatggactt gactgaaggc
    16441 attatccaac acgctgctaa atcagtcaaa ggtgatggcc cagtcaacta ccaaggtact
    16501 gaaatcaaga ttaacgaacc atttaagcgt gttcatatgg tggatgctat cagagaaatt
    16561 actggtgtcg atttctggca agacatgact ttggaagaag ctaaagctat cgctgctgag
    16621 aagaaagttc cagttgagaa acactacact gaggttggtc acatcatcaa tgccttcttt
    16681 gaagagtttg ttgaagaaac tttaatccaa ccaacctttg tctatggaca tccagtagct
    16741 gtatctccac tcgctaagaa aaatcctgaa gaccaacgct ttactgaccg tttcgagctc
    16801 tttatcatga ctaaggagta cggtaatgcc tttactgagt tgaacgaccc aatcgaccaa
    16861 cttagccgtt ttgaagccca agctaaagcc aaagaacttg gtgatgatga agcgacagga
    16921 atcgactatg actacattga agctcttgaa tacggtatgc caccaacagg tggtttggga
    16981 atcggtatcg accgtctctg catgctcctc actgatacaa caactatccg tgatgtattg
    17041 ctcttcccaa caatgaaata aattcttatc ctctggctct taccagggga ttttttgatt
    17101 caaaaagaga ctgaatttaa ggagaaaatg aagtgtagta tattgaagtt gaaatagtac
    17161 actttgattt ctaagacatt gttagaaatt ggtttaaatt ccctaagcaa tttgtgcatg
    17221 ttttatttca ttttacgata gtacgctgaa actgttcaaa aagtactaga aattgacttg
    17281 gattccccaa ttgatttgtt cagattcact ataaataaaa aattaataag tgggatagga
    17341 agttagcgtc aactaggata gtatcttgct taaacagtat atatgggact gatataagtc
    17401 cataggtcct attagaggat gttctggtgt cttattcact tgttttttta tagtattagt
    17461 agatagaatc cgcaaataaa aaagtagttc aaatgcctgg cagcaaaaaa tctcaacgat
    17521 tcacttaata tagactaagg tttagagttt aaggaaagta gggctagtat attgtatgaa
    17581 aaaataagat ggtttttaag caaaactctt gaaaatgatt gaaaaaagag ttattatagt
    17641 tgtgtagtaa aaagcaaacg cttacttaat caaggagggc attttatgtc atacaaaaca
    17701 agcaatgcag aaggtcatgt agacttcatc aatacctatg atttggagcc aatggcgcaa
    17761 caagttattc ctaaagcagc atttggctat atcgctagtg gggcggaaga tactttcact
    17821 ttaagagaga atatccgcgc ctttaaccac aaactcatcg ttcctcatac actttgcgat
    17881 gttgaaaatc caagtacaga gattgaattt gcaggtgaaa aactatcttc accaatcatt
    17941 atggcgcctg ttgcggccca taaattagcg aatgaacagg gggaagtggc gactgcgcgt
    18001 ggtgtgcatg agtttggttc tctttataca accagttctt actctactgt tgaccttcca
    18061 gagatttctg aagcccttca agggacaccc cattggttcc aattttactt tagtaaggat
    18121 gacggtatca accgccacat catggatcgt gtgaaggctg aaggttataa agcgattgtc
    18181 ttgacggcag atgctactgt aggggggaat cgtgaagtgg ataagcgtaa tggttttgtc
    18241 ttcccagttg gcatgccgat tgttgaagaa tacctgccag aaggtgctgg taaatcaatg
    18301 gactttgttt acaaatcagc taaacaacgc ttgtctccac gtgatgtaga atttatcgct
    18361 gaatactcag gacttcctgt gtatgtcaag ggaccacaat gccgtgagga cgttgaacgt
    18421 tcgcttgctg caggagcttc tggtatctgg gtaaccaacc acggtggtcg tcaaatcgac
    18481 ggtggaccag ctgcctttga ctcgcttcaa gaagtggcag aagcagttga taaacgtgtg
    18541 ccaattgtct ttgactctgg tgttcgtcgt ggtcaacatg tctttaaagc cttggcttca
    18601 ggagcagact tggtagctat tggtcgcccg gttatctatg gcttggctct cggcggtagt
    18661 gttggtgtgc gtcaagtctt tgaacacttg aatgcggaat tgaagacagt tatgcagttg
    18721 tctggaactc agactattga agatgttaaa cacttcaaac tccgtcacaa cccatacaac
    18781 ccaactttcc cagttgaccc tcgtgactta agattgtatt gataaaagag attgcctcca
    18841 ctgaatgtgg aggtttttct tcgtgtattg gaagaataaa tcgctatcga aaaccatagt
    18901 aaaatggaat aaaaacagga caaatcaatc aggacagtta aatcgatttt taacaatgtt
    18961 ttagaagtag atgtgtacta ttctagtttc aatctactat atataaagat atttttcggt
    19021 caaatatctt gctagggctt tcattttttg ctatactggt tcagtaatta aataatagag
    19081 acatttgggg tgctttaagc tgagatgata cccattgaac ctgatacagt taagactggc
    19141 gaagggaaat gtgaaacgtt ttttcgtatg acgaaatgaa cgatctaatc ttgtaagtca
    19201 actctaattc ttgattgtaa ttggagtttt ttgtttatat aaactggata ggcttgttta
    19261 gttagctctc tgcaaatgct ctcgatgtgc tttaaaagga tcaagtggaa ttacgatttt
    19321 gcttgatatt tcttggtgtt ttattaatta ctaacaagta aagagaggag aagtaaatat
    19381 ggaaacacaa gactatgcat ttcagccagg tttgactgtt ggagaattat taaaaagcag
    19441 tcagaaggat tggcaggctg caatcaatca tcgttttgtt aaggaacttt ttgcggggac
    19501 aattgagaat aaggtcttaa aggactatct gattcaagat tatcacttct ttgatgcctt
    19561 cttatccatg ctgggtgcct gcgtagctca cgcagataaa cttgaatcca agcttcgttt
    19621 tgccaagcaa ctaggctttc ttgaagcaga tgaagatggt tatttccaaa aggcttttaa
    19681 agagttaaaa gtagcagaga atgactatct agaagtgact ttgcaccctg taacaaaagc
    19741 ctttcaggat ctaatgtatt cggcagtggc ttcatcagac tatgcccatc ttttgattat
    19801 gctggtcatt gcagaaggtc tctatttaga ctggggttct aaagatttgg ctttacctga
    19861 agtctatatt cattcggaat ggatcaatct ccacagaggt cctttctttg cagagtgggt
    19921 tcaatttctg gttgacgaac tcaatcgtgt cggtaaaaat cgagaagatt tgacagaact
    19981 tcagcaacgc tggaatcaag cagtcgcttt agaattagct ttttttgata ttggttacga
    20041 tgtctagaga aggctcatga tatttacaaa tttgatgagg taagactctt cgaaaatctc
    20101 ttcaaaccac gtcagttcta tccacaacct caaaacagtg ttttgagcaa cctgcggtta
    20161 gcctcctagt ttgctctttg attttcattg agtataaatc attcaatgta aatgaaaaaa
    20221 attctcaact aaagataaat cgaaattagt agatcgtata aagtgaaaag gaaggatttc
    20281 aatatgacaa gtttaaaatt attaaaagaa aaagcacctt tggtcatttg catcaccaat
    20341 gatgtagtaa aaaatttcac agcaaatgga ttagtagcac tgggcgcctc accagccatg
    20401 agtgagtttc cagaagattt agaggactta ttaaagtatg ctggtggttt attaataaac
    20461 ataggaacat tgacagatga aaattggaaa ttataccaag ctgctctgaa aattgcagag
    20521 aaatataatg tcccagcagt tttagatcct gtagcctgtg gagcaggaga atatagaaaa
    20581 aaagtagcag atgatttaat caacaattac aaactagctg cgattagggg gaatgctgga
    20641 gagattgcct ctttagtagg aatagatgtg gcatctaaag gagtagatag tgcgggagta
    20701 gataatattg acgagattgc tctagcagca aatgagaagt tcaatattcc aatagtagta
    20761 acaggtgaag tggatgctat tgcggtaaat ggagaagtgg taacgattca taatggtagt
    20821 gccatgatgc caaaagttat tggaactgga tgtttattag gagctgtagt agcaagtttt
    20881 atcggactgg aaaaaggtca agaattaaaa tcattagaaa cagcaatgtt agtttacaat
    20941 atcgctggag aaatggcaga aaaacgtcca aatggacatc ttcctgggac atttaaagtt
    21001 gaatttataa atgccttata cgagattaca gatgaagatg taaaggaatt caaaagagtg
    21061 aagtaagatg tttcataaag aattactaaa actatatttt atttgtggaa cgactacttg
    21121 ccaaggaaaa aatctatata cagtcgttga ggaagcctta aaaggtggta taaccttatt
    21181 tcaatttcga gaaaaaggtg agggtgcttt agaaggctta gaaaaacttg agctagctat
    21241 ccaaattaaa gaactttgta aaaaatacaa tgttccattt atcgttaatg acgatataga
    21301 tttagcaatg gaaattgacg ccgatggcgt acatgtaggt caagatgata ttggtgttga
    21361 tgaaattaga aaattgatgc cagataaaat aattggtctt tctataagaa acgaagaaga
    21421 atttcaacaa tcaaaagttg aatatgtaga ttatgtaggt gttgggcctg tatttgatac
    21481 ccagtcaaaa gatgatgctg gtggtgctat aggttatgaa ggtcttgaat tgatgagaaa
    21541 actattgcca caaatgcctt tagttgcaat tggtgggata cagacgaaac atattaaaga
    21601 cattataaag accaatatgg atggcgtttc aatcatttcg gcaatatcgt atgcaaaaaa
    21661 tatagaaaaa actgttcggg aaatgagtga acaatagata tctatccttg gattctaagt
    21721 aagtaggatt ttcctttttt aaaaagctat gtccagattc agcttgaatg gctaattcat
    21781 caaacaggtc atttgttttt tgcaaaagaa agatctgctg tctttgtgag tgcaaggctg
    21841 tatttccagt tcaatttctt gaactagtat aaaatgtgtg ttataataat cacataatta
    21901 aataataaag acatttgggg tgctttaggc tgagatgata cccattgaac ctgatacagt
    21961 taagactggc gaagggaaat gtgaaatgtt tttttcgtat gtcgaaaaga actgtctaat
    22021 cttgtaagct gaactctaat tcgtatctgt aattagagtt ttttctttta cgaaactgga
    22081 tgaagatgat atagtagatt g
//
LOCUS       DAVKBK010000027        20912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVKBK010000027 DAVKBK010000000
VERSION     DAVKBK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.027"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            98..2320
                     /gene="recJ"
                     /locus_tag="VWX69_001187"
     CDS             98..2320
                     /gene="recJ"
                     /locus_tag="VWX69_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU9192538.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GGASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            2495..4156
                     /locus_tag="VWX69_001188"
     CDS             2495..4156
                     /locus_tag="VWX69_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9192539.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            4225..5004
                     /locus_tag="VWX69_001189"
     CDS             4225..5004
                     /locus_tag="VWX69_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9192540.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            5116..6336
                     /gene="murM"
                     /locus_tag="VWX69_001190"
     CDS             5116..6336
                     /gene="murM"
                     /locus_tag="VWX69_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU9192541.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            6341..7573
                     /gene="murN"
                     /locus_tag="VWX69_001191"
     CDS             6341..7573
                     /gene="murN"
                     /locus_tag="VWX69_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU9192542.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEYFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            7652..8353
                     /locus_tag="VWX69_001192"
     CDS             7652..8353
                     /locus_tag="VWX69_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU9192543.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLAGQ
                     FLSVTVRLNHYYLSNPHYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            8393..10240
                     /gene="uvrC"
                     /locus_tag="VWX69_001193"
     CDS             8393..10240
                     /gene="uvrC"
                     /locus_tag="VWX69_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU9192544.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGSIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            10230..11063
                     /locus_tag="VWX69_001194"
                     /pseudo
     CDS             10230..11063
                     /locus_tag="VWX69_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(11247..12047)
                     /locus_tag="VWX69_001195"
     CDS             complement(11247..12047)
                     /locus_tag="VWX69_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9192545.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            12218..12823
                     /locus_tag="VWX69_001196"
     CDS             12218..12823
                     /locus_tag="VWX69_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU9192546.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            12836..14236
                     /gene="pepV"
                     /locus_tag="VWX69_001197"
     CDS             12836..14236
                     /gene="pepV"
                     /locus_tag="VWX69_001197"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU9192547.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            14290..14868
                     /locus_tag="VWX69_001198"
     CDS             14290..14868
                     /locus_tag="VWX69_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU9192548.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            15028..15180
                     /locus_tag="VWX69_001199"
     CDS             15028..15180
                     /locus_tag="VWX69_001199"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9192549.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            15223..15315
                     /locus_tag="VWX69_001200"
     CDS             15223..15315
                     /locus_tag="VWX69_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9192550.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            15486..16811
                     /gene="brnQ"
                     /locus_tag="VWX69_001201"
     CDS             15486..16811
                     /gene="brnQ"
                     /locus_tag="VWX69_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU9192551.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            16909..17946
                     /locus_tag="VWX69_001202"
     CDS             16909..17946
                     /locus_tag="VWX69_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU9192552.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            17948..18409
                     /locus_tag="VWX69_001203"
     CDS             17948..18409
                     /locus_tag="VWX69_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU9192553.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            18427..19143
                     /locus_tag="VWX69_001204"
     CDS             18427..19143
                     /locus_tag="VWX69_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU9192554.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            19266..19691
                     /gene="rplK"
                     /locus_tag="VWX69_001205"
     CDS             19266..19691
                     /gene="rplK"
                     /locus_tag="VWX69_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU9192555.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            19899..20588
                     /gene="rplA"
                     /locus_tag="VWX69_001206"
     CDS             19899..20588
                     /gene="rplA"
                     /locus_tag="VWX69_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU9192556.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT         6281 a         3859 c         4862 g         5910 t
ORIGIN      
        1 tactatgaaa tgttataaaa aagcaatctg gatagagaaa acgtctaaat catgttataa
       61 tgaagcaata gaattcttag aaggagtgga tgtctttttg ataacaccta cttatgaatg
      121 gcagtttgcc ctgcaggtag aagatgcgga ttttacaaag atagccaaga aggctggact
      181 gggtcctgag gtggctcggt tattgtttga gagagggatt caggaccaag aaagtctgaa
      241 gaagttttta gaaccttcct tggaggactt acatgatgct tatctgctcc atgatatgga
      301 caaggcagtg gagcggattc gtcaggctat tgaagaaagg gaaaatattc tcgtttatgg
      361 agactacgat gcggatggca tgacttcggc ttctattgtg aaggaaagtt tggaacaact
      421 tggtgcggag tgccgagttt acctgccaaa tcgttttacc gatggctatg gccctaatgc
      481 tagtgtttat aaatacttta tcgagcaaga aggaatttcc ttgattgtga cggtggacaa
      541 tggggttgct ggtcatgagg ctattgcatt ggctcagtct atgggagtag atgtcattgt
      601 gacagaccat cattccatgc ctgaaaccct gccagatgct tatgctattg tccatcctga
      661 acatccagat gcggattatc cttttaaata tttggctggt tgtggagttg ctttcaagtt
      721 ggcttgtgcc ctgttagaag aagtgcaagt ggaattgctt gatttggtcg ctattggaac
      781 tattgcagat atggtgagtc tgacggatga aaatcgtatc ttagttcaat atggtctgga
      841 aatgttgggt catacccagc gcattggtct gcaagaaatg ctggacatgg ctgggattgc
      901 tgccaacgaa gtaacagaag aaacggttgg tttccagatt gctcctcgtt tgaatgcctt
      961 gggtcgcttg gatgatccca atcctgccat tgatttgttg actggatttg atgatgagga
     1021 agcgcatgag attgccctta tgattcacca gaaaaacgaa gagcgcaagg aaatcgttca
     1081 gtctatctat gaagaagcca agaccatggt ggatcctgag aagaaggttc aggtcttggc
     1141 caaggaaggc tggaatcctg gggttctagg aatcgtggct ggtcgtttat tggaagaatt
     1201 gggacagaca gtcattgttc ttaatataga agacggtcgt gccaagggca gtgctcgtag
     1261 tgtggaagcg gtcgatattt ttgaagctct ggatccccat cgagacctct tcatcgcctt
     1321 tggaggtcat gcaggtgcag cgggtatgac gctggaagtt gagcaactct cagatttatc
     1381 tcaggttttg gaagattatg ttcgtgaaaa aggtgcagat gctggtggca agaataagtt
     1441 aaacctagat gaagagttgg atttggaggc acttagcttg gaaacggtca aaagttttga
     1501 acgtttagct ccttttggaa tggataatca gaaacctatt ttttatatca agaattttca
     1561 ggtcgaaagt gctcgtacta tgggggcagg taatgcccat ctaaagctga aaatttccaa
     1621 gggtggggcg agttttgaag tggtagcctt tggtcaaggc agatgggcga cagagttttc
     1681 tcaaaccaag aatctagagt tagcggttaa attgtctgtc aaccaatgga atggccaaac
     1741 tgccctccag ttgatgatgg tggatgcgcg agtggaaggt gttcaacttt ttaacattcg
     1801 tggaaaaaat gcagtcttgc cagaaggtgt tccagtcttg gattttcctg gagaactgcc
     1861 aaatcttgcg gctagtgaag ctattgtcgt aaaaaacatt ccagaggata ttactcagct
     1921 gaagaccatt tttcaggaac agcatttctc tgctgtctat ttcaaaaatg atattgacaa
     1981 ggcctattat ctgacaggtt atgggactag agatcagttt gccaaattgt acaagactat
     2041 ttaccagttc ccagagtttg atattcgcta caagctgaaa gatttggctg catatcttaa
     2101 tattcaacaa atcttgctgg tcaagatgat tcaagtattt gaagaactag gctttgtgac
     2161 gataaaagat ggtgtgatga cagtcaataa agaggcgcca aagcgggaga taggagaaag
     2221 tcaaatttac caaaatctca aacaaaccgt taaagaccaa gaaatgatgg cgctgggtac
     2281 ggtgcaagaa atttatgatt ttttgatgga aaaagagtag aagttaggaa agagttggga
     2341 aatcaactct tttttgaaaa cagaccttca ttttgaaaat catcaaaaaa atggtataat
     2401 ggtaggaaaa gattcggctg aaagtattag aacttttaga ataagagggt agagttgccc
     2461 tataatcaag ataaactaag attttggagg aaaaatgagt aatatcagtt taacaacact
     2521 tggtggtgtg cgtgagaatg gaaaaaatat gtacattgct gaaattggag agtccatttt
     2581 tgttttgaat gtagggttaa aatatcctga aaatgaacaa ttaggggtcg atgtggtgat
     2641 tccaaacatg gattaccttt ttgaaaatag cgaccgtatt gctggggttt tcttgaccca
     2701 cgggcatgcg gatgccattg gtgctctacc ttatctcttg gcagaggcta aagttcctgt
     2761 atttgggtct gagttgacca ttgagttggc aaagctcttt gtcaaaggaa atgatgccgt
     2821 taagaaattt aatgatttcc atgtcattga tgagaatacg gagattgatt ttggtgggac
     2881 agtggtttcc ttcttcccta cgacttactc cgttccagag agtctgggaa ttgtcttgaa
     2941 gacatcggaa ggaagcatcg tttatacagg tgacttcaaa tttgaccaaa cggctagtga
     3001 atcttatgca actgattttg ctcgtttggc agagattggt cgtgacggcg tcctggctct
     3061 cctcagtgat tcggccaatg cagacagcaa tattcaggtg gctagtgaaa gtgaagttag
     3121 ggatgaaatt acccaaacta ttgctgactg ggaaggtcgt atcatcgttg cagctgtttc
     3181 cagtaatctt tctcgtattc agcagatttt tgacgctgcg gataaaacag gtcgacgtat
     3241 cgtcttgaca ggatttgata ttgaaaatat cgtccgcaca gcgattcgtc ttaagaagtt
     3301 gtctttagcc aacgaaattc tcttgattaa gcctaaagat atgtctcgct ttgaagacca
     3361 tgagttgatt attcttgaga caggtcgtat gggtgaacct atcaatggac ttcgtaagat
     3421 gtcgattggt cgccatcgtt atgtagaaat caaggatggg gacctggtct atattgctac
     3481 ggctccgtct attgctaaag aagcctttgt tgcgcgtgtg gaaaatatga tttatcaggc
     3541 aggtggggtt gtcaaattga ttacccaaag tttacatgta tcagggcacg gaaatgtgcg
     3601 tgatttgcag ctgatgatca atcttttgca acctaagtac ctcttccctg tccaagggga
     3661 gtatcgtgag ttggatgctc acgctaaggc tgccatggca gttgggatgt tgccagaaca
     3721 catcttcatt cctaaaaagg ggacgaccat ggcttacgag aatggagact ttgttccagc
     3781 tggatcggtt tcagcaggag atatcttgat tgatgggaat gccattggtg atgttggaaa
     3841 tgttgttctt cgtgaccgta aggtcttgtc agaggatgga attttcatcg tggctattac
     3901 agtcaaccgt cgtgagaaga aaattgtggc tagggctcgt gttcatacgc gcggatttgt
     3961 ttatctcaag aagagtcgcg atattctccg tgaaagttca gaattgatta accaaacggt
     4021 agaagagtat cttcaaggag atgactttga ctgggcagat cttaaaggga aggttcgaga
     4081 taatttgacc aagtatctct ttgaccaaac caagcgtcgt ccagctattt taccagtagt
     4141 catggaagca aaataatcgt tgaaataaac agagagaaag tcgagtttcg gctttttctt
     4201 atagaaaaat agaaggagaa aatcatggca gtaatgaaaa tcgagtatta ctcacaagta
     4261 ttggatatgg agtggggggt gaatgtcctc taccctgatg ccaatcgagt ggaagaacca
     4321 gagtgtgaag atattcccgt cttgtacctt ttgcacggga tgtctggaaa tcataatagt
     4381 tggcttaagc ggaccaatgt agaacgcttg cttcgaggaa ctaatctcat cgttgttatg
     4441 cccaatacca gcaatggttg gtacaccgat acccagtatg gttttgacta ctacacggct
     4501 ctagcagagg aattgccaca ggttctgaaa cgcttcttcc ctaatatgac tagcaagcgt
     4561 gaaaagacct ttatcgctgg tctttctatg ggaggctacg gctgcttcaa actggctctt
     4621 gcgacaaatc gtttttctca tgcagctagc ttttcaggtg ccctcagctt tcaaaacttt
     4681 tctcctgaaa gtcaaaatct gggaagtcca gcctactgga gaggtgtttt tggagagatt
     4741 aaagactgga caactagtcc ctattctctt gaaagtctgg ctaaaaaatc ggataaaaag
     4801 accaaacttt gggcgtggtg tggcgaacag gatttcttgt acgaagccaa taatctcgca
     4861 gtgaaaaatc tcaaaaaact aggttttgat gtgacctata gccatagcgc tggaactcac
     4921 gagtggtact actgggaaaa acaattggaa gtttttttaa caaccctacc aattgatttc
     4981 aaattagaag agagactgac ttagtttgaa cttcagcata gggggagtag aactaaaata
     5041 aaatatgttt tcactagact tttcaaacga aagtagtaga atagtaataa aatactggag
     5101 gaaagagagt aggaaatgta ccgttatcaa attggcattc ccacattaga atatgatcag
     5161 tttgtcaaag aacatgaatt agccaatgta ttacaaagta gtgcttggga ggaagttaag
     5221 tctaattggc aacatgagaa gtttggtgtt tacagggaag aaaaattact ggcgacagct
     5281 agtattttga ttagaactct tccgctaggc tataaaatgt tttacatccc aagaggacct
     5341 atattggatt atggggataa agaactcttg aattttgtca ttcagtctat taagtcctat
     5401 gctcgcagta agagagcggt ttttgtgact tttgacccaa gtatttgcct atctcaaagt
     5461 ttaatcaatc aggaaaagac agaatttcct gaaaatctgg ctattattga tagtttgcaa
     5521 caaatgggag taaggtggtc aggaaaaacg gaggaaatgg gagacaccat tcaacctcgt
     5581 attcaggcga aaatatacaa ggaaaatttt gaagaagata aactttccaa gtcaacaaaa
     5641 caggctattc gaacagcacg aaacaaaggg cttgagattc aatatggtgg actggaacta
     5701 ttagattcat tttcggagtt gatgaaaaaa actgagaagc gaaaagagat tcatttgagg
     5761 aatgaagcct attataaaaa attgttagat aattttaagg acaaggccta tatcaccttg
     5821 gccaccttgg atgtttctaa acgttcgcaa gagttagaag aacagttagc gaaaaataga
     5881 gccttggaag agacgtttac tgagtcgact cgaacttcaa aagtagaagc gcagaagaag
     5941 gaaaaagaac gtttgttaga ggaattgacc ttcttgcagg aatatataga tgtaggtcaa
     6001 gcgagagttc ctttagcggc tactttgagt ttggaatttg gtactacctc tgtcaatata
     6061 tatgctggta tggatgatga ttttaaacgt tacaatgcac caattttaac atggtatgaa
     6121 acggctcgct atgcctttga gcgaggtatg gtctggcaaa atttaggtgg tgttgaaaac
     6181 tctctcaatg gtggacttta tcattttaag gaaaaattta atccaacgat tgaagaatac
     6241 ttgggtgaat ttacaatgcc cactcatcct ctctatcctc tgttaagact tgctcttgat
     6301 ttccgtaaaa cattaagaaa aaaacataga aagtaagtat atggcactaa caacactcac
     6361 gaaagaagag tttcagactt attctgatca ggtttcttct cgttccttta tgcaatctgt
     6421 ccagatgggg gatttgctag aaaaaagagg ggctcgaatt gtttatcttg ctttgaaaca
     6481 agaaggagaa attcaagttg cagctctggt ttatagcctg cccatgctgg gtggtctgca
     6541 tatggaactc aattcggggc cgatttatac ccaacaagat gctcttccag ttttttatgc
     6601 agagttaaaa gaatatgcca agcaaaatgg tgtattagag ttgcttgtaa aaccttatga
     6661 aacttatcaa acttttgata gccaaggtaa tccaatagat gctgagaaaa aaagtattat
     6721 tcaaggtttg actgatttag gttatcaatt tgatggctta acaacaggtt acccaggtgg
     6781 agaaccagat tggttatact ataaagattt aactgaatta actgaaaaga gtttgcttaa
     6841 aagttttagc aaaaagggta aacccttggt gaaaaaggct gaaacctttg gcattcggtt
     6901 gaaaaagtta aaacgtgaag aactatcgat ttttaagaat ataacaaaag aaacctctga
     6961 acgtagagaa tatagtgata aaagtttaga atattatgag tatttttatg atacttttgg
     7021 agaacaagcg gagtttctca tagcaagctt gaatttttcg gagtatatga gcaaattgca
     7081 aggtgaacaa agtaaactag aagaaaactt ggacaagttg cgacttgatt tgagtaaaaa
     7141 tcctcattct gagaaaaaac aaaatcaact gagagaatat tctagtcaat ttgaaacgtt
     7201 tgaagttcga aaagcagaag cgcgagactt gattgaaaaa tatggagaag aagatattgt
     7261 tttagctggg agtttatttg tttatatgcc tcaggaaacg acttatctct ttagtggttc
     7321 ctacactgag tttaataagt tctatgcccc tgcactgctt caaaaatatg ttatgttgga
     7381 aagcataaaa cgtggaatac ctaaatacaa tttcctaggc attcaaggga tttttgatgg
     7441 aagtgatggt gttttgcgtt ttaaacagaa ttttaatggc tatattgtac gcaaagcggg
     7501 tactttccgt taccatccat cgcctttaaa atacaaagct atccagttac tcaaaaaaat
     7561 agtaggacgt taagatgaaa aagtcagtat ttagatttct tttagcttct tttagtaaaa
     7621 taattcttat ttgctagaaa ggtggagaga catgcgctgg ctttttcgtt tgataggggc
     7681 tttcttttct tttgtgtggc gtttgttttg gcgtctggtt tggatagttg tgctcttatg
     7741 tgtgcttgct ttcggacttc tctggtatct gaacggggat tttcaaggag cgctaaagca
     7801 agcagaacgg tcagtaaaaa ttggtcaaca aagtattgac caatgggaga aaacagggca
     7861 actgcctaag ttaagccaga cagatagtca ccagcattct gaaggaaggt gggcacaggc
     7921 ctctgctcgt atttacctgg atccgcagat ggattcacgc tttcaagagg cttatttaga
     7981 agcaatccag aactggaatc aaactggtgc ttttaacttt gaactcgtga ctgagtctag
     8041 taaggcggat attacggcta cggagatgaa cgacggaggc actcctgtgg caggagaggc
     8101 ggaaagtcaa actaatctct tagcagggca attcttgtcc gtaacggtgc ggttgaatca
     8161 ttattatttg tccaatccac actatggcta ctcctatgaa cgccttgtcc atacggcaga
     8221 acatgagtta ggtcatgcga ttggcttgga ccatacagat gagaagtctg tcatgcaacc
     8281 agcaggttcc ttttatggta tccaggaaga ggatgttgca aacctccgaa aaatatatga
     8341 gactagtgag tagggtacta tctttcccta ctttttttgc tataatggaa ctatgaacaa
     8401 cttgattaaa tcaaaactag agctcttgcc gaccagccct ggttgctaca ttcataagga
     8461 taaaaatggc tccattatct atgtaggaaa ggctaaaaat ctgcgtaatc gagtacggtc
     8521 ctattttcgt ggaagtcatg ataccaagac agaggctctg gtgtctgaaa ttgtggattt
     8581 tgaatttatt gttacggagt ctaatattga ggcacttctc ctagaaatca acctgatcaa
     8641 ggaaaacaag cccaagtaca atatcatgct caaggatgac aagtcctatc ctttcatcaa
     8701 aatcaccaat gagcgctatc cacgcttgat tatcactcgt caggtcaaaa aggacggagg
     8761 tctttatttt ggaccctatc ccgatgtggg ggcagccaat gaaatcaagc ggttgctgga
     8821 tcggatattc ccttttcgta agtgtaccaa cccgccctct aaggtctgtt tttattacca
     8881 tatcggccag tgtatggctc acaccatctg taagaaggat gaggcttatt tcaagtctat
     8941 ggcccaggag gtttctgatt ttctgaaagg gcaggataac aaaatcattg atgagctaaa
     9001 gggcaaaatg gcagcggcag cccagactat ggagtttgaa cgtgcggcgg aataccgtga
     9061 cctgattcag gctattggaa cgcttcgaac caagcaacgg gtcatggcta aggatctcca
     9121 aaatcgcgat gtctttggct actatgtgga taagggctgg atgtgtgtgc aggttttctt
     9181 tgttcgtcag ggcaagctca tcgagcgcga tgtcaatctc ttcccctact tcaatgatcc
     9241 agatgaggat ttcttgacct atgtgggaca attctatcaa gaaaaatctc acctagttcc
     9301 caatgaggta ctgattccgc aggatattga cgaagaagct gtcaaggctt tggtggatac
     9361 caagattctc aaaccccaac gtggagagaa aaaacagctg gtcaatctag ccataaaaaa
     9421 tgcacgtgtt agtctggagc agaaatttaa cctgctagaa aaatcagtcg aaaagaccca
     9481 aggagctatt gaaaatctag gacgtttgct ccaaattccg actccagttc gcatcgagtc
     9541 cttcgataac tccaacatca tggggaccag tcctgtttca gccatggtgg tctttgttaa
     9601 cggcaggcca agtaaaaaag attaccgtaa gtataaaatc aagaccgtag tcgggccaga
     9661 cgactatgcc agtatgcgag aggtcattcg cagacgctat ggtcgagtac agcgtgaggc
     9721 tttgactcct ccagatttga ttgtgattga tggggggcaa ggtcaagtca atattgctaa
     9781 gcaagtcatc caagaagaac tgggcttgga tattccaatt gcaggtctgc aaaagaatga
     9841 taagcaccaa acccatgaat tgctctttgg agatccgctg gaagtggtgg acttgtctcg
     9901 caattctcag gaatttttcc tcctccaacg cattcaagat gaggtccacc gctttgccat
     9961 taccttccac cgccaactgc gctccaaaaa ttctttctca tctcaattgg atgggattga
    10021 tggtctggga cctaaacgca agcaaaatct catgaggcac ttcaagtctc tgaccaaaat
    10081 caaggaagcc agtgtggatg agattgtcga agttggagta ccaagagcag tagcagaggc
    10141 tgtgcaaacc aagttgaacc cgcaggaaac agaaatcttg cttcaagtgg cggaagaaag
    10201 agtagattac caaacggaag gaaaccacaa taaaccataa aatcgcaatt ttatcagatg
    10261 ttcatggcaa tgcgacggcg ctagaagcag tgattgcaga tgctaaaact caaggagcca
    10321 gtgaatattg gctcatggga gacattttcc tccctggtcc aggtgcaaat gacttggtcg
    10381 ctctgttaaa ggaacttcct atcacggcaa gtgttcgagg caattgggat gattgtgtcc
    10441 ttgaggcttt agatgggcaa tatggcttag aagacccaca ggaagttcag ctcttgcgta
    10501 tgacacagta tttgatggag cgaatggatc ctgcaacgat tgtctggcta cgaagcttgc
    10561 ctttgctgga aaagaaagaa attgacggat tgcgcttttc tatctctcat aatttacctg
    10621 acaaaaacta tggtggtgac ttgctagttg agaatgatac agagaaattt gaccaactgc
    10681 tagatgcgga aacggacgtg gcagtttatg gtcatgttca caagtagttg cttcgttatg
    10741 gtagtcaagg gcaacaaatc atcaatccag ggtcgattgg catgccctat tttaattggg
    10801 aggcgttaaa aaatcaccgt gcccagtatg ccgtgataga ggttgaagat ggggaattgg
    10861 taaatatcct atttcgtaaa gtcgcttatg attacgaggc tgagttagaa tttgccaaat
    10921 ccaagggttt tccctttatc gaaatgtatg aagaactacg tcgtgaagat aactatcaga
    10981 ggcacaatct ggaactatta gcaagcttaa tagaaaagca taggtatgta gaggatgtga
    11041 agaatttttt tgattttttg taagagtttc ctaaaataac caatgcaaac taaaaaagcg
    11101 attggctgat cccatcgctt ttaatatatc ttatactcaa tatgaaaatc aaagagcaaa
    11161 ctaggaagct agccgtaggt tgctcaaagc acagctttga ggttgcagat aaagctgacg
    11221 tggtttgaag agattttcga agagtgttat tgtaactgag attgatctgg gaggtaagaa
    11281 ccacctagat aggtattgct gagtttttca agggttccgt cttgatagag ttctttgagc
    11341 gctttatcaa attgctcttt aaactctttt tggtcgcttg agaaaatgat ataattgctg
    11401 gggctatctg cagaaggtaa atcaacgact gagaggtcta aaccacggtc cttgataatc
    11461 ttttgaacgg ataccttgtc aaaaactagg aaatcaaact ctccgttagc aaggtctagg
    11521 attcgtttac caatatcctc accagaaaaa ttaattgtag cgggattatc agtgtgtttc
    11581 tgattccagt tattgatgaa ttgagcgtta gaagttccgg tatcctcttg tgttgtttta
    11641 ccagcgatct ggtcaagaga agtcaaagga tttttcttgt tgctgacaag gacgagggga
    11701 ttgttggaaa tcggaagcga gtaaaggtat ttttcagcac gctcttttgt gtaactcaaa
    11761 ttattggccg cagcctgata gtgaccagaa tcaagtcctg ggaagatact ttcccaggcg
    11821 gttctttgaa attgaatctc gtagtcgctg agtttttcat ctactgcctt tagaacttcg
    11881 atatcgaagc ctgtcagatt gcctttatct tcgtagtcaa atggtggcac gtcgccagct
    11941 gtagcaagga cgattgtctt ttgagcgcta gtctctttgg gtgtagcttg attcccacag
    12001 gcaaccaaaa atggtaggat agctagtaat aggctaaatt ttttcatact gtctccattc
    12061 aaatgtaaag tacttgctag tttatcagaa actttcctga taaaccaata tatatctttt
    12121 atgtctgtga tagaaaaact taatcatgaa aaatccctgc aagctctttc aaattatggt
    12181 agaatggaag cagtagaatt agaaaaggaa atcgattatg aaatttcttg aattaaataa
    12241 aaaacgtcat gcgaccaagc atttcactga taagcctgtt gatccaaaag atgtgcgtac
    12301 ggctatcgaa attgcaacct tggcgccaag cgcccacaac agccagcctt ggaaatttgt
    12361 agttgttcgt gagaaaaatg ctgaactggc aaagttggct tatggttcaa actttgagca
    12421 ggtatcatca gcacctgtaa ccattgccct atttacagat acagaccttg ccaaacgcgc
    12481 tcgtaagatt gcccgagttg gtggtgctaa caatttctca gaagaacaac ttcaatactt
    12541 catgaaaaat ttgccagctg aatttgcacg ctacaatgaa caacaagtca gcgactacct
    12601 agctctcaat gcaggtttgg ttgccatgaa cttggttctt gcattgacag accaaggaat
    12661 tggttctaac attattcttg gttttgacaa atcaaaagtt aatgaagttt tggaaatcga
    12721 agaccgtttc cgcccagaac tcttgatcac agtgggttat acagacgaaa aattggaacc
    12781 aagctaccgc ttgccagtag atgaaatcat cgagaaaaga tagaaagaag aaaaaatgac
    12841 agcaattgat tttacagcag aagtagaaaa acgcaaagaa gacctcttgg ctgacttgtt
    12901 tagccttttg gaaatcaatt cagaacgtga tgacagcaag gctgatgccc agcatccatt
    12961 tgggcctggt ccagtaaaag ccttggagaa attccttgaa atcgcagacc gcgatggcta
    13021 cccaactaag aatgttgata actatgcagg acattttgag tttggtgatg gagaagaagt
    13081 tctcggaatc tttgcccata tggatgtggt gcctgctggt agcggttggg acacagaccc
    13141 ttacacacca actatcaaag atggtcgcct ttatgcgcgc ggggcttcgg acgataaggg
    13201 tcctacaaca gcttgttact atggtttgaa aatcatcaaa gaattgggtc ttccaacttc
    13261 taagaaagtt cgcttcatcg ttggaacaga cgaagaatca ggctgggcag acatggacta
    13321 ctactttgag cacgtaggac ttgccaaacc agatttcggt ttctcaccag atgctgaatt
    13381 tccaatcatc aatggtgaaa aaggaaatat cacggaatac ctccactttg caggagaaaa
    13441 tacaggtgtt gcccgtcttc acagctttac aggtggttta cgtgaaaata tggtaccaga
    13501 atcagcaaca gcagtcgttt caggtgactt ggctgacttg caagctaaac tagatgcctt
    13561 tgttgcagaa cacaaactta gaggagaact ccaagaagaa gctggcaaat acaaggtgac
    13621 gatcattggt aaatcagccc acggtgctat gcctgcttca ggtgtcaatg gcgcaactta
    13681 ccttgccctc ttcctcagtc agtttggctt tgctggtcca gccaaagact accttgacat
    13741 cgcaggtaaa attctcttga acgatcatga gggtgaaaat cttaagattg ctcatgtgga
    13801 tgaaaagatg ggtgctcttt ctatgaatgc cggcgtcttc cgcttcgatg aaacaagtgc
    13861 tgataatacc attgccctca acatccgcta tccaaaagga acaagtccag aacaaatcaa
    13921 gtcaatcctt gaaaacttgc cagttgtttc tgttagcctg tctgaacacg gtcacacgcc
    13981 tcactatgtg ccaatggaag atccacttgt gcaaaccttg ttgaatatct atgaaaaaca
    14041 aactggcttt aaaggtcatg aacaagtcat cggtggtgga acctttggtc gcttgttaga
    14101 gcgcggagtt gcctatggtg ctatgttccc agactcaatt gataccatgc accaagccaa
    14161 tgaatttatc gccttggacg atctcttccg agcagcagca atctatgccg aagctattta
    14221 cgaattgatc aaataaaacg atagaagtct gagatcttat gcttggactt ctttttggag
    14281 ggaaagtaga tgtctcaaat cgaaagaatc aaacaggcta tcatggcgga ttcacagaat
    14341 gccagctata cagagcgtgg cattgagcct ctctttgcag cgccaaaaac tgctcgcatc
    14401 aatatcatcg gtcaggctcc gggacttaaa actcaagaag caggccttta ctggaaagat
    14461 aaaagtggtg accgcttgcg ggactggcta ggtgtggatg aagatacctt ttacaattca
    14521 ggttattttg ctgttttgcc tatggatttc tactttccag gacatggcaa gtcgggtgat
    14581 cttccgcctc gtacaggttt tgcagaaaaa tggcatccgc agctcttaca ggaattgcct
    14641 gatattcagt taaccctctt gattgggcaa tatgcccaag cctactattt acaggagaaa
    14701 atcagtggga aggtaacgga gagggtgaaa cactataaag actatctgcc agcctatttt
    14761 ccgctagttc acccatcacc acgaaatcaa atctggatgg ccaaaaatcc ttggtttgag
    14821 gcagaagtag tgccagattt gaaaaaaaga attaaaacca ttttatagtc aatgaaaatc
    14881 aaagagcaaa ctaggaagct agtcgtaggc tgctcaaagt acagctttga ggttgcagat
    14941 aaaactgacg aagtcggtaa catacgcacg gtaaggcgac gctgacgtgg tttgaagaga
    15001 ttttcgaaga gtattagaag aaaaagaatg aaagaaatag cctttgacgc attttaccag
    15061 ctttaccaaa acgaccagct ttctctagtg gatgtgagag aagtggatga gtttgcagct
    15121 cttcatttag aatgtgccca caacctaccg cttagtcaat tggctgatag ttatgattaa
    15181 ttggacaaag atcgcttgca ttatattatt tgcaaatctg gaatgagatc ggcgcgtgct
    15241 tgccaattcc tgttagaaca aggttataat gttatcaatg tccagggtgg catgttagcc
    15301 tttgaagaac tttaaaattt tgcatttctc ctgcttggtg tggactgggt aggagagttt
    15361 tatttttaga taattcttat ttttaagaaa attgaaaaca tttaatattt gcctcgtgat
    15421 gcttttttca gactcctaat cgtggtatac taggtcagta ttttataaat atgaaggaga
    15481 tttttatggc taaaaaaggt accctaacag gtttgctcct gtttggaata ttttttggtg
    15541 cggggaactt gatttttccg ccttctctag gtgctctatc tggagaacat tttcttcctg
    15601 ccatcgcagg ttttgtcttt tcaggcgttg gtatcgccgt cttgaccctt attattggaa
    15661 cgctaaatcc taaaggatat atctacgaga tttcaacgaa gatagcgcct tggtttgcga
    15721 ctctttacct ctcagttctt tacttgtcaa tcggtccatt ctttgctacc ccacgtactg
    15781 ctacaacagc ttacgaagta gggattagcc cccttttgtc ggatgcaaat aaaggacttg
    15841 gcttgattgt atttacggtt ctgtattttg cggcagccta tttgatttcg cttaatccat
    15901 caaaaatctt agaccgcatt ggacgtgttt taacgccagt ctttgcaatt ttgattgtta
    15961 tcttggtcgt tctgggagct atcaaatatg gtggaacaag tcctcaagct gcttcagctg
    16021 cttatcaagc ttctgccttt ggtacaggtt tcctagaagg ttacaatacc ttggacgccc
    16081 ttgcttcagt ggcctttagc gtaatcgcag ttcaaacctt gaaacaactt ggattttcaa
    16141 gtaagaaaga atacatttca actatttggg ttgttggtat cgttgttgcc cttgccttca
    16201 gcgctcttta catcggttta ggttttcttg gaaatcattt cccagtacca gctgaagcga
    16261 tgaagggtgg aacaccaggt gtttacatct tgtcacaagc cactcaagaa atctttggct
    16321 caacagctca actcttcctt gcagctatgg ttaccgtaac ctgcttcaca acgactgttg
    16381 gtttgattgt gtcaacagct gagttcttta atgagcgctt cccacaaatc agctacaagg
    16441 tttatgcgac agcctttacc ttgattggat ttgctattgc caatttgggt cttgatgcga
    16501 ttatcaagta ctcaattcca gtactggtta tcttgtaccc aatcacgatt gctatcgtta
    16561 tgattgtcat tgtcaacaaa tttgttgccc tttcaaaacc aggtatgcag ttgacaattg
    16621 ctgtggttac agttattgcc attgcaagcg tactaggaag ctcgtttaag gttgagtttc
    16681 ttgcaaatct tgttagcgtt cttccttttg ccaaggcatc tctcccatgg ttggtgccag
    16741 ccattgttgg aatcttgctc tcattggttc taccaaacaa gcaagaaagc gatgtttttg
    16801 aaatggaata atcacttaaa tcacttttgt agccaagtct acaggagtga ttttcttttt
    16861 ttatccgatg ataaatgtgt tataataggt agcgaaagag gtgaagaaat gaatcaaaca
    16921 gtagaatata tcaaagaact gacagccatc gcatcgccaa cgggcttcac tcgtgaaatt
    16981 tcgaattatt tagtcaagac tctagaaggt tttggttacc agccagttcg cacagctaag
    17041 ggtggtgtca atgtgaccat caaaggtcaa aatgatgagc aacatcgcta tgtgactgcc
    17101 catgtggata cgctgggtgc tattgttcgt gctgtcaaac cagatggtcg tcttaaattg
    17161 gaccgtatcg gtggttttcc ttggaacatg attgaaggtg aaaactgtac cgttcatgtg
    17221 gctagcacag gtcaaaaggt atcaggaacc atcctcatcc accaaacttc ttgccatgtc
    17281 tacaaggatg caggaactgc agaacgcacg caggacaata tggaagtgcg tttggatgta
    17341 aaagtaagca atgaaaaaga aactcgtgct cttgggattg aggtcggtga ttttatcagc
    17401 ttcgatacac gaactgttgt gactgataca ggttttatca agtctcgtca tttggatgat
    17461 aaggtcagcg cagcgatttt gctcaacctg cttcgtattt ataagaaaga gaagattgaa
    17521 ttgccagtaa caactcattt tgctttttca gtttttgaag aagtaggaca tggtgctaat
    17581 tctaacattc ctgctcaggt agtagaatat ctggctgtgg atatgggagc tatgggagat
    17641 gaccagcaga cagatgagta cacagtatct atctgtgtca aggatgcttc aggtccttat
    17701 cactatgact tccgtcaaca cttggttgcc ttggctaaag agcaagatat tccatttaag
    17761 ctcgacatct atccatttta cggatcggac gcttcagcag cgatgtcagc aggtgcagag
    17821 gtcaagcatg cacttcttgg agctggtatt gagtccagtc actcttatga gcgcacccac
    17881 atcgattcag taatagcgac tgagcgtatg gttgatgctt atcttaagag cgaggcggta
    17941 tcatagaatg tgcttaatct gtcagagaat cgaactcatt aaagctgggc aaaatcccta
    18001 ctttgtaaaa gaactagaaa caggctatgt tgttattggt gactaccaat actttaaggg
    18061 ctatacctta tttttagcaa aagatcatgt cacagaactc catcatatgg aaacttctgt
    18121 aaaacttcgc tttttagagg aaatgagttt agtccaagaa gcagtcgcca aagcatttga
    18181 ggctgaaaag atgaatattg aactcctagg aaatggcgat gcccacgctc attggcatct
    18241 ttttccccga agagcaggtg atatgaagag tcacggtttg aatggccgtg gcccagtctg
    18301 gtgggtgccc tgggaagaaa tggcggcaga agattgccaa gtacaatcgc cagagctgga
    18361 agagatgatt aaaatcttat ctcatgaatt ggagaagtat ttggcctaag agagaggaag
    18421 aaagaaatga aaaaaagata tgtcatttta tctggtttac tagcattgac ccttgcagct
    18481 tgttcgcaag aaaaaaccaa agttgaagaa aacactcaaa aaacggagca aagcagtcaa
    18541 ccggaaggaa ctgtaggtag caaatctcaa gcttctagtc agaaaaaggc agaagttagc
    18601 aataaaggga gctattatag tatccaaggg aaatacgatg agattatcct agctaataaa
    18661 cgttatcctt tgtcaaaaga ttacaatcca ggagaaaatc caacagccaa ggcagagttg
    18721 ctcaaactaa tcgcagctat gcaggctgag ggctatccaa tcagtgacca atacagtggg
    18781 tttaggagtt atgaaactca ggctaagctc taccaagact atgtcaatca agatggtaag
    18841 gaagcagcag atcgctactc agcacgccca ggttacagtg aacaccagac gggtcttgct
    18901 tttgatttga ttgggacaga tggggattta gttactgaag aaaaggcagc ccagtggctc
    18961 ttggaccatg cggctgacta tggctttgtt gttcgctatc ttaaaggcaa ggaaaaggag
    19021 actggctaca tggcagaaga atggcatctc cgctacgttg gaaaagaagc caaagaaatt
    19081 gctgcaagtg gtctcagttt ggaagagtac tatggctttg aaggcggcga ttatgtcgat
    19141 taaaaatgaa agttttctct tgcattttta gataaatagt gtataatgga aaggtatgtg
    19201 taaagcatac ttgtgggagg taaaaatctc taattaccgc caaaaccaca aaggaggatt
    19261 taaaaatggc taaaaaagtc gaaaaacttg taaaattgca aatccctgct ggtaaagcta
    19321 caccagctcc accggttgga cctgctcttg gtcaagctgg tatcaacatc atgggattca
    19381 caaaagagtt caacgctcgt acagctgacc aagctggtat gatcattcca gttgttatct
    19441 cagtttacga agataaatca tttactttcg ttacgaaaac accaccagct gctgttcttt
    19501 tgaaaaaagc tgcaggtgtt gaaaaaggat caggtacacc taataaaact aaagttgcta
    19561 cagttactcg tgcacaagta caagaaattg cagaaactaa gatgccagat ttgaacgcag
    19621 caaacgtaga gtctgcaatg cgtatgatcg aaggtactgc tcgttctatg ggattcactg
    19681 ttgttgacta atcaataaca cagtagaaaa tctcacagca gtctattagt tgcttttcat
    19741 actaggcaag tgactgaggc ttgtacttgg atacagcaag ggagcttaag gccgtaggaa
    19801 gagaaaaata gtagactgaa aacccgcaag acttcatcat ttcgagaagt gacgtgggag
    19861 atgaaaatcg attgaaccac ttacaaggag aatagaaaat ggctaaaaaa agcaaacaac
    19921 ttcgtgctgc tcttgagaaa atcgacagca caaaagcata cagtgtagaa gaagctgtag
    19981 cacttgcaaa agaaactaac tttgcaaaat ttgatgcaac tgtagaagtt gcttacaact
    20041 tgaacatcga cgttaaaaaa gctgaccaac aaatccgtgg agcaatggta ttgccaaacg
    20101 gtactggtaa aacttcacgt gttcttgttt tcgcacgtgg tgcaaaagct gaagaagcaa
    20161 aagctgctgg tgcagacttt gttggtgaag atgaccttgt tgctaaaatc aacgacggtt
    20221 ggttggactt cgacgtagtt atcgctacac ctgatatgat ggctcttgtt ggacgtcttg
    20281 gacgtgtcct tggaccacgt aacttgatgc caaaccctaa aactggtact gtaacaatgg
    20341 atgttgctaa agcagttgaa gagtctaaag gtggtaaaat cacttaccgt gctgaccgtg
    20401 caggtaacgt tcaagcaatc atcggtaaag tatcatttga agctgaaaaa ttggttgaaa
    20461 actttaaagc tttcaacgaa acaatccaaa aagtaaaacc agctacagct aaaggaactt
    20521 acgtaacaaa cttgactatc acaactactc aaggtgttgg tatcaaagtt gacgtaaact
    20581 cactttaatc agtagttaaa gtaatgtaaa aaagttgaag acactatgtc tcaacttttt
    20641 ttgatgtacg acgggcatgt cgtatatctg aggtgtaagt cctcggtggg cacctactac
    20701 cggtgaaccc aatagcgatt cccaagtctg acgctggaaa taagaatcgt cagaggaagg
    20761 gatagcgaaa tcgtggctct acgaacagga acgtgataat aaggcctata tagcggataa
    20821 ggtatctggc tggggcgacc actatcaatt ataataaaat gaaataagaa taggacgaat
    20881 cgttcaggac agtcaaatcg atttctaaca at
//
LOCUS       DAVKBK010000028        20714 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVKBK010000028 DAVKBK010000000
VERSION     DAVKBK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.028"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            110..2092
                     /locus_tag="VWX69_001207"
     CDS             110..2092
                     /locus_tag="VWX69_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9192557.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKVLDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2393..7696
                     /locus_tag="VWX69_001208"
     CDS             2393..7696
                     /locus_tag="VWX69_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9192558.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDERDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KQALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEITVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASVTVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(7863..10022)
                     /locus_tag="VWX69_001209"
     CDS             complement(7863..10022)
                     /locus_tag="VWX69_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU9192559.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10019..10615)
                     /gene="recU"
                     /locus_tag="VWX69_001210"
     CDS             complement(10019..10615)
                     /gene="recU"
                     /locus_tag="VWX69_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU9192560.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10681..11208
                     /locus_tag="VWX69_001211"
     CDS             10681..11208
                     /locus_tag="VWX69_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU9192561.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            11278..11607
                     /gene="gpsB"
                     /locus_tag="VWX69_001212"
     CDS             11278..11607
                     /gene="gpsB"
                     /locus_tag="VWX69_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU9192562.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11628..12008
                     /gene="rnpB"
                     /locus_tag="VWX69_001213"
     ncRNA           11628..12008
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VWX69_001213"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12093..13250
                     /locus_tag="VWX69_001214"
     CDS             12093..13250
                     /locus_tag="VWX69_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU9192563.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREMRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13263..14657
                     /gene="mapZ"
                     /locus_tag="VWX69_001215"
     CDS             13263..14657
                     /gene="mapZ"
                     /locus_tag="VWX69_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU9192564.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLGKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14733..16157
                     /gene="gndA"
                     /locus_tag="VWX69_001216"
     CDS             14733..16157
                     /gene="gndA"
                     /locus_tag="VWX69_001216"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU9192565.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPYLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16169..16858
                     /locus_tag="VWX69_001217"
     CDS             16169..16858
                     /locus_tag="VWX69_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9192566.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGIGYTMQE"
     gene            16956..17978
                     /gene="cbpC"
                     /locus_tag="VWX69_001218"
     CDS             16956..17978
                     /gene="cbpC"
                     /locus_tag="VWX69_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU9192567.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDPSNGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            17996..18994
                     /gene="cbpJ"
                     /locus_tag="VWX69_001219"
     CDS             17996..18994
                     /gene="cbpJ"
                     /locus_tag="VWX69_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEU9192568.1"
                     /translation="MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(19112..20344)
                     /locus_tag="VWX69_001220"
     CDS             complement(19112..20344)
                     /locus_tag="VWX69_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9192569.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(20387..>20714)
                     /locus_tag="VWX69_001221"
     CDS             complement(20387..>20714)
                     /locus_tag="VWX69_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU9192570.1"
                     /translation="LSWCKGISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGY
                     CHGITSLLQTTVYNQNKLLMKKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSM
                     GYIGVY"
BASE COUNT         6462 a         3727 c         4710 g         5815 t
ORIGIN      
        1 ttttttgtct tttcagaata taccaaatta acacaaaaat tctgaaaatt ctgttgacat
       61 ctttctgaaa agagtttata atggagagaa agttttaaag gagaaaatga tgaaaagttc
      121 aaaactattt gcccttgcgg gcgtgacatt attggcggcg actactttag ctgcatgctc
      181 tggatcaggt tcaagcacta aaggtgagaa gacattctca tacatttatg agacagaccc
      241 tgataacctc aactatttga caactgctaa ggctgcgaca gcaaatatta ccagtaacgt
      301 ggttgatggt ttgctagaaa atgatcgcta cgggaacttt gtgccgtcta tggctgagga
      361 ttggtctgta tccaaggatg gattgactta cacttatact atccgtaagg atgcaaaatg
      421 gtatacttct gaaggggaag aatacgcggc agtcaaagct caagactttg taacaggact
      481 aaaatatgct gctgataaaa aatcagatgc tctttacctt gttcaagaat caatcaaagg
      541 gttggatgcc tatgtaaaag gggaaatcaa agatttctca caagtaggaa ttaaggttct
      601 ggatgaacag acagttcagt acactttgaa caaaccagaa agcttctgga attctaagac
      661 aaccatgggt gtgcttgcgc cagttaatga agagtttttg aattcaaaag gggatgattt
      721 tgccaaagct acggatccaa gtagtctctt gtataacggt ccttatttgt tgaaatccat
      781 tgtgaccaaa tcttctgttg aatttgcgaa aaatccgaac tactgggata aggacaatgt
      841 gcatattgac aaagttaaat tgtcattctg ggatggtcaa gataccagca aacctgcaga
      901 aaactttaaa gatggtagcc ttacagcagc tcgtctctat ccaacaagtg caagtttcgc
      961 agagcttgag aagagtatga aggacaatat tgtctatact caacaagact ctattacgta
     1021 tctagttggt acaaatattg accgtcagtc ctataaatac acatctaaga ccagcgacga
     1081 acaaaaggca tcgactaaaa aggctctctt aaacaaggat ttccgtcagg ctattgcctt
     1141 tggttttgat cgtacagcct atgcctctca gttgaatgga caaactggag caagtaaaat
     1201 cttgcgtaat ctctttgtgc caccaacatt tgttcaagca gatggtaaaa actttggcga
     1261 tatggtcaaa gagaaattgg tcacttatgg ggatgaatgg aaggatgtta atcttgcaga
     1321 ttctcaggat ggtctttaca atccagaaaa agccaaggct gaatttgcta aagctaaatc
     1381 agccttacaa gcagaaggtg tgacattccc aattcatttg gatatgccag ttgaccagac
     1441 agcaactaca aaagttcagc gcgtccaatc tatgaaacaa tccttggaag caactttagg
     1501 agctgataat gtcattattg atatccaaca actacaaaaa gacgaagtaa acaatattac
     1561 atattttgct gaaaatgctg ctggcgaaga ctgggattta tcagataatg tcggttgggg
     1621 tccagacttt gccgatccat caacttacct tgatatcatc aaaccatctg taggagaaag
     1681 tactaaaaca tatttagggt ttgactcagg ggaagataat gtagctgcta aaaaagtagg
     1741 tctatatgac tacgaaaaat tggttactga ggctggtgat gaggctacag atgttgctaa
     1801 acgctatgat aaatacgctg cagcccaagc ttggttgaca gatagtgctt tgattattcc
     1861 aactacatct cgtacagggc gcccaatctt gtctaagatg gtaccattta caataccatt
     1921 tgcattgtca ggaaataaag gtacaagtga accaatctta tataaatact tggaacttca
     1981 agacaaggca gtcactgtag atgaatacca aaaagctcag gaaaaatgga tgaaagaaaa
     2041 agaagagtct aataaaaagg ctcaagaaga tctcgcaaaa catgtgaaat aactgttgca
     2101 aaatataaga aaggatttag tatttctctt gaatgctgaa tcctttttta catttgtaaa
     2161 gaaagattct aaatgtactg acccccaaaa gttggagcct ctttttgtca gaatagagaa
     2221 aatttttgtt aattttactt gtttcctatt gctttatcag ttattatttg ttatattaaa
     2281 agtataatta ttttttattt atcagggtta agcattgcac tttcagagga aggagtattt
     2341 tttaaaaagg aaatgtaaac gcttgcccaa aaatgaaagg atttagaagt ttatgaataa
     2401 aggattattt gaaaaacgtt gtaaatatag tattcggaaa ttttcattag gtgttgcttc
     2461 tgttatgatt ggagctgcat tctttgggac aagtccggtt cttgcagata gcgtgcagtc
     2521 tggttctacg gcgaatttac cagctgattt agctactgct cttgcaacag caaaagagaa
     2581 tgatgagcgt gattttgaag cgcctaaggt gggagaagac caaggttctc cagaagttac
     2641 agatggacct aagacagaag aagaactatt agcacttgaa aaagaaaaac cggctgaaga
     2701 aaaaccaaaa gaggataaac ctgcagctgc taaacctgaa acacctaaga cggtaacccc
     2761 tgaatggcaa acggtagaga aaaaagaaca acaaggaaca gtcactatcc gagaagaaaa
     2821 aggtgtccgc tacaaccaac tatcctcaac tgctcaaaat gataacgcag gcaaacaagc
     2881 cctgtttgaa aagaagggct tgaccgttga tgccaatgga aatgcaactg ttgatttaac
     2941 cttcaaagaa gattctgaaa agggcaaatc acgctttggt gtcttcttga aatttaaaga
     3001 taccaataat aatgtttttg tcggttatga caaggatggc tggttctggg agtataaatc
     3061 tccaacaact agcacttggt atagaggtag tcgtgttgct gctcctgaaa caggatcaac
     3121 aaaccgtctc tctatcactc tcaagtcaga cggtcagcta aatgccagca ataacgatgt
     3181 caatctcttt gacacagtga ctctaccagc tgcggtcaat gaccatctta aaaatgagaa
     3241 gaagattctt ctcaaggcgg gctcttatga cgatgagcga acagttgtta gcgttaaaac
     3301 ggataaccaa gagggggtaa aaacagagga tacccctgct gaaaaagaaa caggtcctga
     3361 agttgatgat agcaaggtga cttatgacac gattcagtct aaggtcctca aagcagtgat
     3421 tgaccaagcc ttccctcgtg tcaaggaata cagcttgaat ggacatactt tgccaggaca
     3481 ggtgcaacag ttcaaccaag tctttatcaa taaccaccga atcacccctg aagtcactta
     3541 taagaaaatc aatgagacaa cagcagagta cttgatgaag attcgcgatg atgctcactt
     3601 aatcaatgcg gaaataacag tacgcttgca agttgtggac aatcaattgc actttgatgt
     3661 gaccaagatt gtcaaccaca atcaagtcac tccaggtcaa aagattgatg acgaaagaaa
     3721 actactttct tctattagtt tcctcggcaa tgctttagtc tctgtttcta gtgatcaaac
     3781 tggtgctaag tttgatgggg caaccatgtc aaacaatacg catgtcagcg gagatgatca
     3841 tatcgatgta accaatccaa tgaaggattt ggctaagggt tacatgtatg gatttgtttc
     3901 tacagataag cttgctgctg gtgtttggag taactctcaa aatagctatg gtggtggttc
     3961 gaatgactgg actcgtttga cagcttataa agaaacagtc ggaaatgcca actatgtagg
     4021 aatccatagc tctgaatggc aatgggaaaa agcttataag ggcattgttt tcccagaata
     4081 cacgaaggaa cttccaagtg ctaaggttgt tatcactgaa gatgccaatg cagacaagaa
     4141 agttgattgg caagatggtg ccattgctta tcgtagcatt atgaacaatc ctcaaggttg
     4201 ggaaaaagtt aaggatatca cagcttaccg tatcgcgatg aactttggtt ctcaagcaca
     4261 aaacccattc cttatgacct tggatggtat caagaaaatc aatctccaca cagatggtct
     4321 tgggcaaggt gttctcctta aaggatatgg tagcgaaggc catgactctg gtcacttgaa
     4381 ctatgctgat attggtaagc gtatcggtgg tgtcgaagac ttcaagaccc taattgagaa
     4441 ggctaagaaa tatggagctc atctaggtat ccacgttaac gcttcagaaa cttatcctga
     4501 gtctaaatac ttcaatgaaa aaattctccg taagaatcca gatggaagct atagctatgg
     4561 ttggaactgg ctagatcaag gtatcaacat tgatgctgcc tatgacctag ctcatggtcg
     4621 tttggcacgt tgggaagatt tgaagaaaaa acttggtgac ggtctcgact ttatctatgt
     4681 ggacgtttgg ggtaatggtc aatcaggtga taacggtgcc tgggctaccc acgttcttgc
     4741 taaagaaatt aacaaacaag gctggcgctt tgcgatcgag tggggccatg gtggtgagta
     4801 cgactctacc ttccatcact gggcagctga cttgacctac ggtggctaca ccaataaagg
     4861 tatcaacagt gccatcaccc gctttatccg taaccaccaa aaagatgctt gggttgggga
     4921 ctacagaagt tatggtggtg cagccaacta tccactgcta ggtggctaca gcatgaaaga
     4981 ctttgaaggc tggcaaggaa gaagtgacta caatggctat gtaaccaact tatttgccca
     5041 tgacgtcatg accaagtatt tccaacactt cactgtaagc aaatgggaaa atggtacacc
     5101 ggtgactatg accgataacg gtagcaccta taaatggact ccagaaatgc gagtggaatt
     5161 ggtagatgct gacaataata aagtagttgt aactcgtaag tcaaatgatg tcaatagtcc
     5221 acaatatcgc gaacgtacag taacgctcaa cggacgtgtc atccaagatg gttcagctta
     5281 cttgactcct tggaactggg atgcaaatgg taagaaactt tctactgata aggaaaagat
     5341 gtactacttc aatacgcagg ccggtgcaac aacttggacc cttccaagcg attgggcaaa
     5401 gagcaaggtt tacctttaca agctaactga ccaaggtaag acagaagagc aagaactaac
     5461 tgtaaaagat ggtaaaatta ctctagatct tctagcaaat caaccatacg ttctctatcg
     5521 ttcgaaacaa accaatcctg aaatgtcatg gagcgaaggc atgcacatct atgaccaagg
     5581 atttaacagt ggtaccttga aacattggac catttcaggc gatgcttcta aggcagaaat
     5641 tgtcaagtct caaggggcaa acgatatgct tcgtattcaa ggaaacaaag aaaaagttag
     5701 tctcactcag aaattaactg gcttgaaacc aaataccaag tatgccgttt atgtcggtgt
     5761 cgataaccgt agtaatgcca aggcgagcgt cactgtaaat actggtgaaa aagaagtgac
     5821 tacttatacc aataagtctc tcgccctcaa ctatgtaaaa gcctacgccc acaatacacg
     5881 tcgtaacaat gctacagttg acgatacaag ttacttccaa aacatgtacg ccttctttac
     5941 aactggatcg gacgtatcaa atgttactct gacattgagt cgtgaagctg gtgatcaagc
     6001 aacttacttt gatgaaattc gtacctttga aaacaattca agcatgtacg gagacaagca
     6061 tgatacaggt aaaggcacct tcaagcaaga ctttgaaaat gttgctcagg gtatcttccc
     6121 atttgtagtg ggtggtgtcg aaggtgttga agataaccgc actcacttgt ctgaaaaaca
     6181 caatccatat acacaacgtg gttggaatgg taagaaagtc gatgatgtta tcgaaggaaa
     6241 ttggtcactc aagacaaatg gactagtgag ccgtcgtaac ttggtttacc aaaccatccc
     6301 acaaaacttc cgttttgaag caggtaagac ctaccgtgta acctttgaat acgaagcagg
     6361 atcagacaat acctatgctt ttgtagtcgg taagggagaa ttccagtcag gtcgtcgtgg
     6421 tactcaagca agcaacttgg aaatgcatga attgccaaat acttggacag attctaagaa
     6481 agccaagaag gcaaccttcc ttgtgacagg tgcagaaaca ggcgatactt gggtaggtat
     6541 ctactcaact ggaaatgcaa gtaatactcg tggtgattct ggtggaaatg ccaacttccg
     6601 tggttataac gacttcatga tggataatct tcaaatcgaa gaaattaccc taacaggtaa
     6661 gatgttgaca gaaaatgctc tgaagaacta cttgccaacg gttgccatga ctaactacac
     6721 caaagagtct atggatgctt tgaaagaggc ggtctttaac ctcagtcagg ccgatgatga
     6781 tatcagtgtg gaagaagcgc gtgcagagat tgccaagatt gaagctttga agaatgcttt
     6841 ggttcagaag aaaacggctt tggtagcaga tgactttgca agtcttacag ctcctgctca
     6901 ggctcaagaa ggtcttgcaa atgcctttga tggcaatgtg tctagtctat ggcatacatc
     6961 ttggaatggt ggagatgtag gcaagcctgc aaccatggtc ttgaaagaac caactgaaat
     7021 cactggactt cgttatgttc cacgtggatc aggttcaaat ggtaacttgc gtgatgtgaa
     7081 acttgttgtg acagatgagt ctggcaagga gcataccttt actgcaactg attggccaga
     7141 taacaataag ccaaaagaca ttgattttgg taagacaatt aaggctaaga aaattgtcct
     7201 tacaggtact aagacttacg gagatggtgg cgataaatac caatctgcag cggaacttat
     7261 ctttactcgt ccacaggtag cagaaacacc tcttgacttg tcaggctatg aagcagcttt
     7321 ggctaaggct cagaaattaa cagacaaaga caatcaagag gaagtagcta gcgttcaggc
     7381 aagcatgaaa tatgcgacgg ataaccatct cttgacggaa agaatggtgg aatactttgc
     7441 agattatctc aaccaattaa aagattctgc tacgaaacca gatgctccaa ctgtagagaa
     7501 acctgagttt aaacttagct ctttagtttc caatcaaggt aagacgccag attataagca
     7561 agaaatagat agaccagaaa cacctgaaca aatcttgcca gcaacaggtg agagtcaatc
     7621 tgacacagcc ctcttcctag caagtgttag tctagcccta tctgctctct ttgtagtaaa
     7681 aacgaagaaa gactagtatt tagtaaaacc tcttaacaag attacggaag cagtctctat
     7741 cttttccaat gaggtttata gtacagaaaa agcctgagaa gatgtcttct caggcttttg
     7801 ttaagcacat aaatacaata gtgctatgac aaaatcaccc agaaaaatct gggtgataaa
     7861 tgttatggtt gtgctggttg aggattctga ttttgttgat caggggttgt atttgattgt
     7921 tgcgtattat tgttaggatt ggtagtcgta ctattatttg tgcttggagt ggttgagcta
     7981 gactgtgaag ttgaactatc tgatgatgag cttgaacttt cagttgatgg gggttgttgt
     8041 ggagcaggtg agttccacgt agaacgagca ccatttttaa atacgaattc tccatttctg
     8101 tagagcccct ctggtatatt ccaatcctct ggattgcttc cttcagacag ataggtcatc
     8161 atagagcggt aaactttggc agcgaccgta aggccattgc ctacaagtgg tgtcagacgg
     8221 ttagaatagc ctgtccatac agccattgaa tatttacgcg tatagccagc aaatagttca
     8281 tcaggtgcta caaattgaga ggtcttgatg tggttttcaa tttcctcgtc tgtatagtta
     8341 gaggttcctg ttttaccagc ctgagggagc caagcaagat aggcatttcg tccagttcca
     8401 taactcaaga ctgttttcat catgtcggtc atcatatagg ctgtcgtttc cttcatggca
     8461 cgagttccga cattagagaa ctctttttca ctcccatcac taaagacgac tttatggata
     8521 tacattggtt tatagtaagt tccaccattt gcaaaggcag cgtaagcagc agccatcttt
     8581 tcactacttg ctccatattt tttgtctgat tcggttgtgt tacttgaaat ggcatttgag
     8641 tagtgaatac ttgggtagtc gattccgaga ccatttagga aagtcttggc gcggttgagt
     8701 ccgaccttgt ttagagtttc cacggctggg acgtttcgcg attgttgcag ggcgtattgc
     8761 aaggtgatgt tgccaaagta gcccctatcc cagttataaa caggggtatt tgtcccaggg
     8821 tagttatagg gctcatcgtg aacgatagta gcagttgaat cgtagatacc gtactccaag
     8881 gcaggagcat agtctgtgat cggtttcata gttgatcccc agtcgcggtt tgtttctact
     8941 gcttggttaa ttccgaagga aacattactt gactgatggc gtgctcctag ctgggcaatg
     9001 actttaccgt tagaaacatc aacaatggta gaagcgactt gcaattcatc gtctggatag
     9061 gcaacgtatt cgtctgtatt gtaaatatcc cacagatgtt tttgagcttc ttggtctaca
     9121 tttgtgtaga catccatccc agttgtgagc aggttatagc ctgtttcttc ttcaacttga
     9181 ttgatgactt ccttgaggta attatccatg taagcagggt aattacttgc tgatttgaga
     9241 ctttgtagtc catcagtaat tggtgtattg actgctttct catactgttc agcagagatg
     9301 tagccttgat ttttcatttc agataagacc aagtttcggc ggtcttgggc tgcttctgga
     9361 tgtgaatagg ggtcatattg gtttggtgcc tgaggcattc cagccagcaa ggctaactga
     9421 ggtaaactta aattattgag gtctttacca tagtagtttt gagctgctgt ctgcattcca
     9481 tagttcccat tagacatgta gaccttattt atatagtagg tcaagatttc ttgcttggtt
     9541 gctttttgtt ctaactgaat cgctaaccaa gcttcctgag ccttacgaga aatagtctgg
     9601 tcggaagtcg aagttgaaaa gtaagtcaac ttaatcaact gttgggtgag agttgatcca
     9661 ccttggaggg aattgctttg cagattgcgc aagaaagctc ctaggatacg gatggtatca
     9721 atccccctgt ggtcgaagaa gcgatggtct tcgatagaaa cgattgcctt aaccaaatct
     9781 gtgggaatat cattagcttg ggcattgacg cggcgttcag aacccaagtc agcaatgagt
     9841 tgatttttat tgtcgtagat tttactagaa gttgttgcaa ctagtttact ctcggatagg
     9901 ctaggagcct tgctaacgta gtagaaaaaa actcctccgc ctaagacaat ggctgcgata
     9961 accaagctta agaagctaat gctcagatac ttgattaggc gcagaatcgt tggtttgttc
    10021 atcttgtttt accacctaat aaatgttctt tgataacatt gagataagga atttgaggga
    10081 aggcaccagc cttgatttca tatccatatt ctcgaatata ttcaagtggc attgattttt
    10141 gtcccttatc ttgatgatag aagcgaatca aatcgaatgc cggcaataag taggtttctt
    10201 gctgagaaga aaagtgaaga aggacaaagc agattccttg ttgggcaagg acttgttcca
    10261 tatgctgaat ctgatgtgga tgaaaatttt tcatcggaat cgcacgtttt tgttttgttt
    10321 ccttgacttc aaagtcgatg taatatccat tataaacgcc agaatagtcc gtcgttgaag
    10381 cttgtcgaaa ataggcttca acaatcttgg cacgacttcg ttgtggatag tccacttgta
    10441 cgatttgaat aggagttggt ttcttatgta taacagccaa gccctgagac aaatagtagt
    10501 cgttggtagc attgatcatc ttttcaaaag acattcctcg atttgcgaaa tttttgggtt
    10561 gagaaagaga tgtttgtctt ttttgtgatg aaactttatg tggatagttg accataattc
    10621 tccttattgg tacaataaca tcactttatt ataccataat ttgcacagaa agggttaaaa
    10681 atggctacag ctttggtttt aggctattct gcttttgatt tgggtttatt ttctgataag
    10741 gatcctcgtc ttaaattgat taaaaaagcg atacgtaaag atttagaggc tatggcagca
    10801 gatggggtgt cttggcttgt gtttacaggg agtttgggtt ttgaatattg ggttttagag
    10861 gttgctcagg agatgaaaac tgaatacggt ttccagttgg ccaccatttt tgcttttgaa
    10921 acccatgggg aaaattggaa tgaaggcaat cagatgaaac tgagtcgctt taagcaggta
    10981 gactttgtca aatatgccta tcctcgctat gaacacaagg ggcagttaag agattaccag
    11041 cagtttttgc tggaaaacac gactagttcc tatctttttt atgatgaaga aaatgaaaca
    11101 aaactagctt atttttacca aaagatgaaa aatcaagagg actattttat aaagagatta
    11161 acatttgatg aattaaatga acttgctgaa aatttttccg aaaattgaag ctttgacctt
    11221 gatttttgtt tgcctttttt tatataataa tactagcaag cgagaatgga gagagacatg
    11281 gcaagtatta ttttttcagc gaaagatatt tttgaacaag agtttggacg tgaagtccgt
    11341 ggctataata aagtagaagt tgacgagttt ttagacgatg tcatcaagga ctatgaaacc
    11401 tatgctgcct tggtcaagtc acttcgtcag gaaattgcgg atttgaagga agaattaact
    11461 cgtaaaccga aaccttcacc agttcaagca gaaccccttg aagcggcaat tacaagttct
    11521 atgacgaatt ttgatatttt gaaacgcctg aatagattgg aaaaagaagt ttttggtaaa
    11581 caaattttag ataactcaga tttttaagta gttatttgag atgtgcaatt tttggataat
    11641 cgcgtgagga gaattgcttc tcatgaggaa agtccatgct agcacaggct gtgatgcctg
    11701 tagtgtttgt gctaggcgaa accataagcc tagggacgag aaatcgttac ggcagttgaa
    11761 atggctaagt ccttggatag gccagagtag gcttgaaagt gccacagtga cggagtcttt
    11821 ctggaaacag agagagtgga acgcggtaaa cccctcaagc tagcaaccca aattttggtc
    11881 ggggcatgga gtacgcggaa acgaacgtag tattctgact gctatcagct agagctgtta
    11941 gtggtagaca gatgattatc gaaggaagtg gtcctagtca cttctggaac aaaacatggc
    12001 ttatagaaaa ttgcatatag gttggggctg agaaattttc tcaacctcat tttttaaagt
    12061 ggacatatag aaaggtcttg caagactgta acatgaaaaa agaatttaat ttaattgcaa
    12121 ctgtggcagc agggcttgag gctgtcgttg gtcgtgaaat gcgagagttg ggctacgatt
    12181 gtcaggttga aaatggacgt gttcgttttc aaggagacgt gagagctatt atcgaaacca
    12241 acctttggct tcgggcagca gatcgtatca aaattatcgt aggaacgttc ccagctaaga
    12301 cttttgaaga gctatttcag ggagttttcg ctttagattg ggaaaattat ttaccacttg
    12361 gagctcggtt cccgatttca aaagctaaat gtgttaagtc caaacttcac aatgagccca
    12421 gtgttcaggc tatttctaag aaagctgttg tcaagaaatt gcagaaacac tatgctcgcc
    12481 cagaaggggt tcctctgatg gagaatggtc cagagtttaa gattgaggtc tctattctca
    12541 aagatgtggc aactgtcatg attgatacga ccgggtctag cctctttaaa cgtggttatc
    12601 gtaccgaaaa aggtggcgct cctatcaagg aaaatatggc agcagccatt ttacaacttt
    12661 ctaactggta tccagacaag cctttgattg atccgacctg tggttcgggg actttctgta
    12721 ttgaggcagt tatgattgct agaaagatgg cgccaggtct tcgtcgttct tttgcatttg
    12781 aggaatggaa ctggatcagc gatcgcttga ttcaagaagt gcgcacagaa gcggctaaaa
    12841 aagtagaccg tgagcttgag ctggatatca tgggctgtga tattgatgct cgcatggtgg
    12901 aaattgctaa ggccaatgct caggtagctg gtgttgcagg agacattact tttaagcaga
    12961 tgcgcgtgca ggatttatgt tccgataaaa tcaatggagt aatcatttcc aatccgcctt
    13021 atggtgaacg tttgtcagat gatgcagggg tgaccaagct ctatgctgag atggggcaag
    13081 tatttgcacc gctgaaaact tggagcaaat ttatcctgac tagtgatgaa gcttttgaaa
    13141 gcaagtatgg tagccaagca gataagaagc gtaagttata caacggaacc ttgaaagtgg
    13201 atctatatca atattttggt cagcgtgtca aacggcaaga ggtaaaatag aaagggatac
    13261 tcatgagtaa aaaaagacga aatcgtcata aaaaagaagg tcaagaaccg caatttgatt
    13321 ttgatgaagc aaaagagcta acagttggtc aagctattcg taaaaatgaa gaagtggaag
    13381 caggagtctt gcctgaggat tccattttgg acaagtatgt taagcaacac agagatgaaa
    13441 ttgaggcgga taagtttgcg actcgtcaat acaaaaaaga ggagttcgtt gaaactcaga
    13501 gtctggatga tttaattcaa gagatgcgtg aggctgtaga gaagtcagaa gcttcttcgg
    13561 aggaagttcc atcttctgaa gacatcttac tacccttgcc tctggacgat gaggagcaag
    13621 gcttggatcc tctattgcta gatgatgaaa atccaacaga aatgactgaa gaagtggaag
    13681 aggagcaaaa cctttctcgt ctggatcaag aggactcaga aaagaaaagt aaaaaaggct
    13741 ttattttgac cgttttggcg cttgtatcag taattatttg tgtcagtgct tattatgtct
    13801 accgtcaagt ggctcgttcg actaaggaaa ttgaaacttc tcaatcaact acagccaatc
    13861 aatcggatgt ggatgatttt aatacacttt atgacgcctt ttacacagat agcaataaaa
    13921 cggctttgaa aaatagccag tttgataaac tgagtcaact caagacttta cttgataagc
    13981 tggaaggtag tcgtgaacat acgcttgcca aatctaaata tgatagtcta gtaacgcaaa
    14041 ttaaggccat tcaagatgtc aatgcacaat ttgaaaaacc agctattgtg gatggtgtgt
    14101 tggataccaa tgccaaagcc aaatcggatg ctaaatttac agatattaaa actgggaata
    14161 cggagcttga taaagtgcta ggtaaggcta tcagtcttgg taagagccag caaacaagta
    14221 cttctagctc aagttcaagt caaactagca gctcaagctc tagtcaagca agctcaaata
    14281 cgactagtga gccaaaacca agtagttcaa atgagactag aagtagtcgc agtgaagtca
    14341 atatgggtct ctcgagtgca ggggttgctg ttcaaagaag tgccagtcgt gttgcctata
    14401 atcagtctgc tattgatgat agtaataact ctgcctggga ttttgcggat ggtgtcttgg
    14461 aacaaattct agcaacttca cgttcacgtg gctatatcac tggagaccaa tatatccttg
    14521 aacgtgtcaa tatcgttaac ggcaatggtt attacaacct ctacaagcca gatggaacct
    14581 atctctttac ccttaactgt aagacaggct actttgtcgg aaatggcgct ggtcatgcgg
    14641 atgacttgga ttactaagca gtcgttacaa aattctttct tttcaaaagt aaaaatgata
    14701 aaataaaaca aatgaaacaa gaggagtgtc aaatgacaaa agctaacttt ggtgttgtag
    14761 gtatggccgt aatgggtcgt aaccttgccc ttaatattga atcacgtggt tacacagttg
    14821 ctatctacaa ccgtagtaaa gaaaaaacgg aagatgtgat tgcttgccat cctgaaaaga
    14881 actttgtacc aagctatgac gttgaaagtt ttgtaaactc aatcgaaaaa cctcgtcgta
    14941 tcatgctgat ggttcaagct ggacctggta cagatgctac tatccaagcc cttcttccat
    15001 accttgacaa gggtgatatc ttgattgacg gtggaaatac tttctacaaa gataccatcc
    15061 gtcgtaatga agaattggca aactcaggta tcaactttat cggtactggg gtttctggtg
    15121 gtgaaaaagg tgcccttgaa ggtccttcta tcatgcctgg tggacaaaaa gaggcctacg
    15181 aattggttgc ggatgttctt gaagaaatct cagctaaagc accagaagat ggcaaaccat
    15241 gtgtgactta catcggccct gatggagctg gtcactatgt gaaaatggtt cacaatggta
    15301 ttgagtacgg tgatatgcaa ttgatcgcag aaagctatga cttgatgcaa cacttgctag
    15361 gcctttctgc agaggatatg gctgaaatct ttactgagtg gaacaagggt gaattagaca
    15421 gctatttgat cgaaatcaca gctgatattt tgagccgtaa agacgatgaa ggccaagatg
    15481 gaccaatcgt agactacatc cttgatgctg caggtaacaa gggaactggt aaatggacta
    15541 gccaatcatc tcttgacctt ggtgtaccat tgtcactgat tactgagtca gtgtttgcac
    15601 gctacatttc aacttacaaa gaagaacgtg tacatgctag caaggtgctt ccaaaaccag
    15661 ctgccttcaa ctttgaagga gacaaggctg aattgattga aaagatccgt caagcccttt
    15721 acttttcaaa aatcatttca tacgcacaag gatttgctca attacgtgta gcctctaaag
    15781 aaaacaactg gaacttgcca tttgcagata tcgcatctat ctggcgtgat ggctgtatca
    15841 tccgttctcg tttcttgcaa aagattacag atgcttacaa ccgtgatgca gaccttgcca
    15901 accttctttt ggatgaatac ttcttggatg ttactgctaa gtatcaacaa gcagtgcgtg
    15961 atatcgtagc tcttgcggtt caagctggtg tgccagtgcc aactttctca gcagctatta
    16021 cttactttga tagctaccgt tcagctgacc ttccagctaa cttgatccaa gcacaacgtg
    16081 actactttgg tgctcacact taccaacgta aagacaaaga aggaaccttc cactactctt
    16141 ggtatgacga aaaataagta ggtcagccat ggggaaacgg attttattac ttgagaaaga
    16201 acgaaatcta gctcattttt taagtttgga actccagaaa gagcagtatc gggttgatct
    16261 ggtagaggag gggcaaaaag ccctctccat ggctcttcag acagactatg atttgatgtt
    16321 attgaacgtt aatctgggag atatgatggc tcaggatttt gcagaaaaat tgagccgaac
    16381 taaacctgcc tcagtcatca tgattttaga tcattgggaa gacttgcaag aagagctgga
    16441 agttgttcag cgttttgcag tttcatacat ctataagcca gtccttatcg aaaatctggt
    16501 agcgcgtatt tcggcgatct tccgaggtcg ggacttcatt gatcaacact gcagtctgat
    16561 gaaagttcca aggacctacc gcaatcttag gatagatgtt gaacatcaca cggtttatcg
    16621 tggtgaagag atgattgctc tgacccgccg tgagtatgac cttttggcga cacttatggg
    16681 aagcaagaaa gtattgactc gtgagcaatt gttggaaagt gtttggaagt atgaaagtgc
    16741 gaccgagaca aatatcgtag atgtctatat ccgctatcta cggagcaagc ttgatgttaa
    16801 aggacaaaaa agctacatta aaactgtgcg tggtattgga tataccatgc aagaatagaa
    16861 aagcagttgc agttgtgtaa ctgctttttt gaggagtttt tatatattga catgcagtcg
    16921 ggtctttgct acaatcgttt taggaggata tatagatgaa acttttgaaa aaaatgatgc
    16981 aagttctact agcagtcttt ttctttggtt tgctagctac aaatacggta tttgcgaata
    17041 ccacaggtgg ccgatttgtt gataaggata atagaaaata ttatgtaaaa gatgatcata
    17101 aagcaatcta ttggcataaa atagacggta aaacttacta ttttggtgat attggagaga
    17161 tggttgtcgg ttggcaatac ttagaaattc ctggaacagg ttatcgtgat aatttattcg
    17221 ataaccaacc agttaatgaa attggccttc aggagaagtg gtactatttt ggacaagatg
    17281 gtgctttgct agaacaaaca gataaacaag tactagaggc aaaaacgtct gaaaatacag
    17341 gaaaagtata cggtgaacaa tatcctctat ctgctgaaaa gagaacttat tattttgata
    17401 ataattatgc tgtaaagaca ggctggattt atgaagaggg tcattggtat tatttaaata
    17461 agctaggaaa ttttggcgat gattcttaca atccactacc aattggtgaa gttgctaagg
    17521 gttggactca agattttcat gttactattg acattgatag aagcaaacct gctccatggt
    17581 actacctaga tgcttcaggt aagatgctta cagattggca aaaagtaaac ggaaaatggt
    17641 attattttgg ctcctctggt tctatggcaa caggttggaa atatgtacga ggcaaatggt
    17701 attacttaga taataaaaat ggtgatatga aaacaggatg gcaatacctt ggtaacaagt
    17761 ggtactacct ccgttcatca ggagctatgg taactggctg gtatcaagat ggttcaactt
    17821 ggtactattt agatccttct aatggagata tgaaaatagg ttggacaaaa gtaaatggaa
    17881 aatggtatta tctcaattca aatggagcaa tggttacagg tagccaaact atcgatggta
    17941 aagtttataa tttcgcctca tctggtgagt ggatttaata ttggagggta tatagatgaa
    18001 aattttgaaa aaaactatgc aagttggact gacagtattt ttctttggtt tgctagggac
    18061 cagtacagta tttgcagatg attctgaagg atggcagttt gtccaagaaa acggaagaac
    18121 ctactacaaa aagggggacc tcaaagaaac ctactggcga gtgattgatg gtaagtacta
    18181 ttattttgat tctctatctg gagagatggt tgtcggctgg caatatatcc cgtttccatc
    18241 taaaggtagt acaattggtc cttacccaaa tggtatcaga ttagaaggtt ttccaaagtc
    18301 agagtggtac tacttcgata aaaatggagt gctacaagag tttgttggtt ggaaaacatt
    18361 agagattaaa actaaagaca gtgttggaag aaagtacggg gaaaaacgtg aagattcaga
    18421 agataaagaa gagaagcgtt attatacgaa ctattacttt aatcaaaatc attctttaga
    18481 gacaggttgg ctttatgatc agtctaactg gtattatcta gctaagacgg aaattaatgg
    18541 agaaaactac cttggtggtg aaagacgtgc ggggtggata aacgatgatt cgacttggta
    18601 ctacctagat ccaacaactg gtattatgca aacaggttgg caatatctag gtaataagtg
    18661 gtactacctc cgttcctcag gagcaatggc cactggctgg tatcaggaag gtaccacttg
    18721 gtattattta gaccacccaa atggcgatat gaaaacaggt tggcaaaacc ttgggaacaa
    18781 atggtactat ctccgttcat caggagctat ggcaactggt tggtatcaag atggttcaac
    18841 ttggtactac ctaaatgcag gtaatggaga catgaagaca ggttggttcc aggtcaatgg
    18901 caactggtac tatgcttata gctcaggtgc tttggcagtg aatacgaccg tagatggcta
    18961 ttctgtcaac tataatggcg aatgggttcg gtaatgacag ggcgcttata attatattag
    19021 aacactcgct taatcaaaga agtgactttg ttgtacttga cctgacgatt ggggagatta
    19081 aaagcatgtg aaatctacac atgctttttc gttagttatg agtgttgaac ttgactaacc
    19141 attgacaaaa gataagagca attaaaataa gatacaaaaa tatcaatgct aactgcaccg
    19201 aaacgcccga tgctatggat agggctaata gggagagcag ggacggggcg agaatgtcca
    19261 ctgtgctcag agcagagccc accgtcccca tcttgtcact ggggatatgg gcaaagacag
    19321 ctgcttgtag gcgagggctg agaatgccga taatcgtaga actgatgaaa ctggtcatga
    19381 aaattacgat ataggcttga caaaggatac tagttattag agtcaatagg gaaatctcac
    19441 agaaaaccaa gaggtgcgtg aaacggatat ttttaaatag attactgctg gtcatattgc
    19501 caaggatagc tccacaagac atgatgatgg agagcagggc gaggagttgc ccaatgctca
    19561 gttgtgctag tgtctgttgg atgaagcgga gggcaatcag ccgaggggac acatccaaga
    19621 tggcaatcat actggtcgtc agaaacagta gtatgacggt atcttttaac ctcaggagca
    19681 cagccagcga ctgtttaaga tgttgaaaat atttcttaaa actcagtgct gtatgtgaca
    19741 tttcaattct tttttcaacc tcatacaagg tatgtcgaat aacatacagg cccaaaaagg
    19801 caatgacaaa agtcagagtg ttgataaggg aaatagtttg aatacttata acattgataa
    19861 ggaatgcgcc agccagattg gcgacaatac ggacaaccct catcagagac tgcctgaacc
    19921 ccatggcatc atgcaggtcg tccttaatta cactgatgta gagggcgttc atcatgtagg
    19981 cagacaggta gctcaaggtg tcagagatga ggttgatgat gacaatcata atgactgaaa
    20041 ctaatgaaaa gggcgacaag acgagaaata ctgtcaaaat agcgtagagc aggattttga
    20101 ttttggcaat ccagagtgcg tgtttgactc tattttcttg aaaatctcct agaatcccga
    20161 gaaagagttg cgatagtagg ggaaccatct ctgaaatgga aatcagtaaa atcgctagcg
    20221 gagcgaaatt gtactgagcc acataattga taatggcgag gtagaaaata ctgtcgccga
    20281 atgatgaaaa acagctgttt agcagcaact gtctatatat gttgtttgtc caaaataatt
    20341 tcatactttt ctccttatgt ctgcacatcg aatgggaatt tattatttaa tagacaccaa
    20401 tataccccat gcttcctatt ccgaagtcaa acaaatctgc tttaccacta tctccttgaa
    20461 acataagtaa accgtgatca tctcgttcag aacatgctaa aattacctgt tggatttttt
    20521 tcatcagtaa tttgttttga ttgtagacag tggtttgtag taagctagtt attccgtggc
    20581 aatatcctgt catcattttt agatgatggt taaaaacaaa ttcttgatat ttactaataa
    20641 tatctttgtt tccgtcacaa tcgtacatac aaagatataa gattattccg gaaattcctt
    20701 tgcaccaaga aagt
//
LOCUS       DAVKBK010000029        20468 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVKBK010000029 DAVKBK010000000
VERSION     DAVKBK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.029"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(72..221)
                     /locus_tag="VWX69_001222"
                     /pseudo
     CDS             complement(72..221)
                     /locus_tag="VWX69_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(375..2006)
                     /gene="rlmD"
                     /locus_tag="VWX69_001223"
     CDS             complement(375..2006)
                     /gene="rlmD"
                     /locus_tag="VWX69_001223"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9192571.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLDMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2080..3054)
                     /locus_tag="VWX69_001224"
     CDS             complement(2080..3054)
                     /locus_tag="VWX69_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU9192572.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3128..3742)
                     /gene="pmp23"
                     /locus_tag="VWX69_001225"
     CDS             complement(3128..3742)
                     /gene="pmp23"
                     /locus_tag="VWX69_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU9192573.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVQLNLYIIKCFTLFSTSG"
     gene            complement(3742..4716)
                     /locus_tag="VWX69_001226"
     CDS             complement(3742..4716)
                     /locus_tag="VWX69_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU9192574.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4724..5980)
                     /locus_tag="VWX69_001227"
     CDS             complement(4724..5980)
                     /locus_tag="VWX69_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU9192575.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            complement(6042..6473)
                     /locus_tag="VWX69_001228"
     CDS             complement(6042..6473)
                     /locus_tag="VWX69_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192576.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6475..7077)
                     /locus_tag="VWX69_001229"
     CDS             complement(6475..7077)
                     /locus_tag="VWX69_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU9192577.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7061..7900)
                     /gene="prmC"
                     /locus_tag="VWX69_001230"
     CDS             complement(7061..7900)
                     /gene="prmC"
                     /locus_tag="VWX69_001230"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU9192578.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(7900..8979)
                     /gene="prfA"
                     /locus_tag="VWX69_001231"
     CDS             complement(7900..8979)
                     /gene="prfA"
                     /locus_tag="VWX69_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU9192579.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(8976..9566)
                     /locus_tag="VWX69_001232"
     CDS             complement(8976..9566)
                     /locus_tag="VWX69_001232"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU9192580.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            9689..9871
                     /locus_tag="VWX69_001233"
     CDS             9689..9871
                     /locus_tag="VWX69_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU9192581.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10007..11380
                     /gene="mnmE"
                     /locus_tag="VWX69_001234"
     CDS             10007..11380
                     /gene="mnmE"
                     /locus_tag="VWX69_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU9192582.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11427..12362)
                     /gene="dapA"
                     /locus_tag="VWX69_001235"
     CDS             complement(11427..12362)
                     /gene="dapA"
                     /locus_tag="VWX69_001235"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU9192583.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12418..13494)
                     /locus_tag="VWX69_001236"
     CDS             complement(12418..13494)
                     /locus_tag="VWX69_001236"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU9192584.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14125..14197)
                     /locus_tag="VWX69_001237"
     tRNA            complement(14125..14197)
                     /locus_tag="VWX69_001237"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14162..14164),aa:Thr,seq:ggt)
     gene            complement(14297..14806)
                     /locus_tag="VWX69_001238"
     CDS             complement(14297..14806)
                     /locus_tag="VWX69_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU9192585.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14804..14900)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            14929..15360
                     /locus_tag="VWX69_001239"
     CDS             14929..15360
                     /locus_tag="VWX69_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU9192586.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15442..15819
                     /gene="mscL"
                     /locus_tag="VWX69_001240"
     CDS             15442..15819
                     /gene="mscL"
                     /locus_tag="VWX69_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU9192587.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15861..16955)
                     /gene="hemH"
                     /locus_tag="VWX69_001241"
     CDS             complement(15861..16955)
                     /gene="hemH"
                     /locus_tag="VWX69_001241"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU9192588.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17110..18333
                     /gene="pepT"
                     /locus_tag="VWX69_001242"
     CDS             17110..18333
                     /gene="pepT"
                     /locus_tag="VWX69_001242"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU9192589.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18369..18998)
                     /locus_tag="VWX69_001243"
     CDS             complement(18369..18998)
                     /locus_tag="VWX69_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192590.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            18963..19184
                     /locus_tag="VWX69_001244"
     CDS             18963..19184
                     /locus_tag="VWX69_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192591.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19455..20466)
                     /locus_tag="VWX69_001245"
                     /pseudo
     CDS             complement(19455..20466)
                     /locus_tag="VWX69_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         5900 a         4310 c         3862 g         6396 t
ORIGIN      
        1 tttggtagaa gtcttgaact ccttatattt acataactat ttgcctctat aactgttatg
       61 acacgaaacc aacaagcaag ttcaagcacc tccatatctt tattcaaatg aggactaaga
      121 tattcacaaa ctttatcata aacctcttta tcttttttca taaaaggggc atacaactta
      181 gcaaatttat cctaaaattt tttgttgcct ttatcaatca tttcaacgct cctttaaata
      241 taaaaatgat cctatcaatc tttatattga gcctattttc taattgatac cttgcaagaa
      301 aggaataata gctgttccta taccaagtag gaatgtaata aatgcagaaa gtcatatact
      361 gtcattcttt tctattaaat cattttgaag tgtctcaaag catccatgat ggcttcttct
      421 ttttcaggtg tacactgtgg aataatttgt ttatcctttt tagacttgtt gtaatgttct
      481 cgtaattcta ttccacattt cttttttatc tgtgcaatat ataatgtcga aacttttaat
      541 tcaaatttat tccaaacata ttctttgatt tgagcatatg ttgctttgct ctccgcactt
      601 gtcaaatcca tctcatccag ctcaatttca acacttatgt gcttatcgac atcgagtttg
      661 gacaaaagtg ctaccgtctc gacgtgatgc gtttgaggaa atagatccac cggctggact
      721 ttcttcaatt catatcccaa ctcttggtat agtttaatat cacgcgccat ggttgcgaca
      781 ttgcaggaga tataggcgat gcgatcggct cctgtttggg cgcttgcttt gataaagctt
      841 tctgtcaagc ccttgcgtgg aggatcaacc aagataacgg ttggttgaat accttccttg
      901 agccatttct tcatggcatt ttcagccgtg tcacagacat agtgggcatt agtaatcttg
      961 ttcaaagaag cattcttctg gctattctct actgcttctg gaatcagttc aacaccgtag
     1021 acttctttga catgcttggc gactgataaa ccaatggttc caataccaga ataggcatca
     1081 ataatcacat catctttttt taactctgca aagtcaatgg ctgtttgata gagtttctcc
     1141 gccatttcag tattgacttg gtaaaaggct gggccagcga tttggaagtc atttcccaac
     1201 atctggtccg taatatagtc ttgaccataa agagtgcgcc actccttacc aaaaatcgca
     1261 ttggtattct ggtcgttgat attttgcatg acagacacaa tctctgggaa ctgcttgata
     1321 acttgttcaa tcaattggtc aacacgaaaa acttttggac gagttgtcac caaaacgacc
     1381 atgatttgtc ctgaatagtg accacgacgc accacaagat tccgaatcaa tccagattgt
     1441 tccttttcgt cataaggttt taaatcaaaa cgacggagca ggtctcgaag agctactacg
     1501 acttggtcaa tgacaggatc ctggataaag aaatcttcaa ggggcatgag gttatgcgaa
     1561 ttcttacgga aaaatcctgt ttccaagaca ccattcactc gacgaacggg cacctgcgcc
     1621 ttattgcgat acttgactgg atgttccata tcaagcgttt cagcaacttc tacatctgca
     1681 attccagcaa tcttgtagag actgtccttg acttgcttgg ttttaaactt gagctgttct
     1741 ggataagaaa ggtgtcctaa atccgcgatt cctgaacgca ggtaagccaa atctagatct
     1801 tgattacggt gtggtgactg gacaaggtat ttttcaactt ttccaaagcc aatcttttta
     1861 ttgaccttga ggacacgcat gagaattttt tcactcggta aagcattctc tacaaaaaag
     1921 accaaaccat ctaccttggc aactcctgcc ccttcatggg tcaaatcaac aatttcaact
     1981 tctacaatat catttttctt taacattctt ttctctttct attggccgac aaaaaagacg
     2041 gcaacgttac ggttaccatc cattatacca tgaaatttct taagaaccaa aactcttgaa
     2101 gaagttgaca agggcttgcc agagggagct taagaagtta ccaccgtcct ctagcgcctt
     2161 atccgcatca aagttaaggt tgatattttt aaaactgtcg ccagcttgtg atacgatgct
     2221 ttgtttaagg tcatttaggg ttttagtgaa atctgcattg ctgaggatat cactctttga
     2281 gagattcaag gcaaaattga tgatgatatt gatctggttt cctgttatga cctgatcaag
     2341 tttgtaattt tttaaggtat cttcaacaat cttgcgtaca tcttcttctg tcagatttcc
     2401 cttgctttct ttagctttgg cgagtcctga cttgatatca gctagggcaa cgtttaattt
     2461 attagcatca tagcctgatt tgtccttgtt ttcagcattg atatctgaca aagcctttag
     2521 ctcttcttga gccaaatctt tattggcttg cggcaccttg gctccattag cttctagcga
     2581 atagtagatc ccagccaaag cactctcacc tgtaactgga ataggggctg ctacagtgat
     2641 tttggcatgt tccataccca gcgttactgc tgcgtttcgg tacatatcct gagtcacctt
     2701 agtgatattt tctggtgttt caatcttgac ctcaagtggc gatttgtcac ctagcttttg
     2761 aatcttggct gatgaataca actgtaagct agagtcattg gccacattca tgattttaga
     2821 ataaacatca ggtgtcatgg tcttgagttc tttggtatct gttgaggcat tgtagcccag
     2881 ttttttaaga gtttgatttt tttggtcttc agatagggag gaacctagga catattcagg
     2941 ttggacatag gtttcatcga taactttttg aacatctgtt gctgcatgga cgctattcat
     3001 agctgttact gcccacaaga ccgcagcact agtcagaaag agtttctttc tcatagggaa
     3061 tttcctcctt tacctttcta gagtaatata tctatcttaa agaaaactta taacaaaaac
     3121 acctgaacta gccagatgtt gaaaagagag tgaaacattt gatgatgtaa aggttgagtt
     3181 gcacctgtct agaataataa tagtttcctc catttacata gagttcggca ccgtgaaaaa
     3241 tggaaatggg atgaatataa ctataagtct ttccagtcgt attaccaagc aagggggcaa
     3301 cagtctcacg agagtactgt ttggctagag ccaaggtatt ttccttgcca ttttgggcga
     3361 taaaatcgat ataggcaggt ccaaaattat aggcttgaac agctgtccag atatctacac
     3421 ccttcttctg cgccagatag agattgcctg tcagagtttg aatgccttgc cgaatgctag
     3481 aggcattatc attgatggtg ttggtggaac cacttgcaga ctcactagac tgcataacat
     3541 cgccttcttt tccttttgtt tcagtataaa tcatagcaag cacaagctct tcgtttgctg
     3601 gggtgtcttt ttcactcaat atttctcgca ccatgggttg ataggtcatg acttgtttga
     3661 catcttgatg aacgcggtaa gctttatagc cagcaaaaag gaagactgct agtacaagca
     3721 ctcttcgaat tcgtttaaac attatttact ttggatatcc tcgatatttt tgattaagat
     3781 agagtaggtt ccattttcgt tttggataaa ctcaacagac tcggcgtctt gatagacgtt
     3841 attgggaacg atgagctcaa ttccatttga taaggagagt ttttggtttt caaatttctt
     3901 taattggcga ctgacatcaa tttcatcaaa ttgaacaggt tctggtacgg cttctttgac
     3961 ttggtcaata aagctcaaac gagccgtcag attgttgtca aaaaggtcat tagccaattt
     4021 ctcaggtgac aattcattgc tttcttctag gttgttgaaa atagctgatt tgaccttgga
     4081 ttgaaattga aaatcatctg tgttaaaaga ttcagcaatt ctctgggctg ttttttccag
     4141 ttccttgata gattttttag gagaaatctt aggagcgaca gcaagaagat tatctgaaaa
     4201 atagttcaaa aaagtcccgt tgtacttgat tcgtttttca atcaggtgat acttgctact
     4261 ctgaagattg accaccaagg cctcatcagc tcctgttcca aatccaggca ggttattctg
     4321 agttagcttg attggattat caacttctcc tccgaggtgg gtcaaggtct cccgcagggc
     4381 aattcgcaag aaagcgaaat gttctacacc ttctttagaa aattgaacaa aaatcaagtc
     4441 attggtcttg agattttcag aaatgctaaa ctcctctttc cagagattag ccagcgttac
     4501 tgatgtctcc aacaaatcgt ctgtaatatg attgaagaag ggattttctt cttcgaaaat
     4561 cccagtcttg gcttcatctg aatacacatg ttcaattttt ttacgcaggt attcttcgat
     4621 ttttggagta atattgagaa acttatctgc taagaacagt tcggtatcat ccggactgaa
     4681 ctggtgaata atggctttct taatataaat gtccataaaa gttttagtcc tcgtatagta
     4741 ggaaggcatc tgtcaattct ttgactgcac ttctcacttc ttctaataca gcctcatttt
     4801 ctgaattctt aagggtttta atgatgagtt cagccacttt gcgactttct tcttcaccaa
     4861 atccacgtgc agtaatggct gctgctccga tacgaatccc acttgtcttg aatggtgaca
     4921 agctttcgta agggattgag tttttattta aggtaatatt gacttcatcc aacaagtttt
     4981 gagcaacttt gccgttttct acaactttag tcacatcaac aaggaagaga tggttttcag
     5041 ttccacctga aataatacgg aaatcagggt cttgcaagaa gacatctgcc atagccttgc
     5101 tgttcttaat tacattggca gcatattcct tgaaggctgg atccaaaact tctttgaagg
     5161 aaactgcctt agccgccaca acatgctcta aaggaccgcc ctgaatacct gggaaaatag
     5221 ctgaattgat ttttttagca agttcttcgt cattggtcaa aatcaaacca ccacgaggtc
     5281 cacgaagggt tttgtgggtc gttgttgttg tgatatgagc gtatggaact gggcttggat
     5341 gaaggccagc cgcaaccaaa ccagcgatat gggccatgtc caccatgagc ttcgcaccga
     5401 cagcatctgc gatttcacgg aattttgaaa aatcgataat ttgagaatat gctgaagcac
     5461 cagctacaat cagttttggt tttacttctt gggcttgttt caagatagca tcaaagtcta
     5521 agagttccgt ttcaggatca acactataag aaacaaagtt gtaggtttga ccagagaagc
     5581 taacaggagc cccatgagtc aaatgaccac ctgatgccaa atccattccc ataaccgtat
     5641 cacctggctc aatcaaggac atgtaagccg cacagttagc ttggcttcct gaatgtggtt
     5701 ggacattggc aaatttagca ccgaaaattt cttttgcgcg ttcaatagca agagtctcta
     5761 caacgtctac tacatcagtt ccaccataat aacggcgtcc tgggtaaccc tcggcatatt
     5821 tatttgtcaa gatagaccct tgagctgcca taacagcctt ggaaactacg ttttccgaag
     5881 caattaactc gatattattt tgttggcgtt cttcttcttt ggcaatagca ttccagagat
     5941 cagcatcata tgctttaaaa tcatctttgt caaaaatcat aggtcttctc ctttattgtg
     6001 tgactagtcc attagtttga ttttacaata agaaaatcaa actaaaagat gcgaataaac
     6061 cgtttctgca ttttatcaca agtatagcca actttttcat aaaatgcatg agcacccaga
     6121 cgatgattgg cagaatttaa gcggataaac ccataaccac atctttttgc ttcttcttcc
     6181 aacccttgta gtaaactttt accaatacct tgaccttgcg cttgaggtga aactgctaaa
     6241 gctaagatat taaatcctgc tttggaatag agtgattcgt aaacttcagc gtggacatat
     6301 ccaagtaaga catgattagc tgcatcctca tagccaagta ggaaatgatg ggaatcctga
     6361 gacagtctag ctagttggct agccgtttcc tctggactaa aagtataacc caaagcctct
     6421 tggttgatgt cacatatcgc tttcacatct gtttcttgca aatctcttag catttcaagc
     6481 ctcctcaaaa gaaatctctg gcaaccgagc aagaatatct tctcgtttaa ttgcgccttg
     6541 gcgtaagatt ttcaccttgt ctccagacaa atccacaata gttgaatcct gtccagttag
     6601 aaaagcatcg tcttccagac ccagaacctc ttggtcaaaa tccttcagaa tttgttcaaa
     6661 ggttacacca cttgcctgac ctgagatatt ggcagacggc ccaatcaagg gacctgtctc
     6721 tcgaattaaa tccagtgtga tagggtgact gggcatccga aatccaatag ttgcaaggtc
     6781 agaatttacc caatagggaa ctcggtcatt ggcttcgaga ataatggtca agggacctgg
     6841 caaaaaggtc tctacaagtt tttgtagata agttggctga ttcttagaaa agtgcaagat
     6901 atcctcgaaa gaggcgatat tgagattgag tgccttatct ctaggacgac gtttgagttg
     6961 gtaaacatgg tcaactgctt tttcatctaa ggccttggca aaaagaccat aaacagtctc
     7021 tgtaggtaga acgacagctc caccattttc caactcttgt ctaatcctgt ccatcatcaa
     7081 ccacaaccat cctattttga ccaaattggt ctttgagtgt tcgaactttt ttttcaggaa
     7141 gatgttttct aaaaagttcg ggaacacttt gaccttgctt gtatccaatt tcaaggtaaa
     7201 tcttaccacc atccttgaga tagtcttttg catcttccgc aattctacag taaatagcta
     7261 ggccatcctc gtctgcaaag agagctagat gaggctccga atgcaaaaca ttcaaaccta
     7321 cctctgactc atcttcacga gagatatagg gtggattgga tacaattata tcatattttt
     7381 cagaaatttc tgcaaaacaa tcagattttt taaaaaatat attaagattt tgatcgctag
     7441 cattctctga tgcaagctct aaggcctctt gagaaacatc tgctgctgtc actgaccaat
     7501 ctggtctatt ttttgctaga gcgagagcaa tagctccact acctgttcca atatccagaa
     7561 ctgagagatt cgtctcaaga ttttcagtta gaataagctc cactaactcc tctgtttctg
     7621 gacgaggaat caaaacccgt tcatccacct ttaaatgcat tccataaaaa tctgcctgtc
     7681 caatgatgta ctgagctggc ttgtgagctg ctagttgctg gtaaatatct tctacaaatt
     7741 gtttttcttc ctctgttgtc acctcctgct ggagggcaaa aataaagtct gtaaaagata
     7801 gatttttcag actacgatag acaaaagaga ggctttccgc ttcctctcct tgtcttatca
     7861 actcttcttc aaaatttgaa aataattgag ctaatttcat tatttgttta attcttctag
     7921 tttttgtgtt tggtcataaa gcaccaaggc atccacaact tcgtccaatt taccagacaa
     7981 aatcgtatct agtttttgga gggtcaagcc gatacggtgg tctgtgacac ggttttgtgg
     8041 gaagttataa gttcggatcc gttctgaacg gtcaccagta ccgattgtcg acttacgctc
     8101 agcgtcttgt tcatcctgag caatctgagc aaagtggtca gcgacgcgtg cacggataat
     8161 cttcatagcc ttctcgcggt tcttctgctg ggtacgttct tcctgcatct caaccttgat
     8221 attggttggc aagtgaacga tacgaacggc agtcgcaacc ttattgacgt tctgtccacc
     8281 agcaccagag gcgtgataga tgtcgacacg aaggtctttt ggatcaatgt cgtattcaac
     8341 ctcttcaact tctggcataa caagaactgt cgctgtcgaa gtatgaacac ggccttggct
     8401 ttctgtcaca ggaacacgtt gcacacggtg ggcacctgat tcatacttaa gcttagagta
     8461 tacagactga cctgaaacca tagcaaccac ttctttaaaa ccaccgacac cattcataga
     8521 ggcttccatg acttcaaagc gccaaccttg ggcttccgca tacttttggt acatagttag
     8581 caaatctcca gcgaaaagtg ccgcttcgtc tccaccagct gctccacgga tttcaaggat
     8641 gatattcttg tcatcgtttg gatcctttgg aaggagcaaa attttcagtt tttcttcata
     8701 ttcttctttt tcagccttgg catctttgag ttcttgcttg gccatttctt ccaagtccgc
     8761 atctccgcct gattccttaa tcatctcttc ggcatcgacg atattttgaa ggacttgttt
     8821 atactcacgg taggctatta cggtgtcacg attggaagct tcttcttttg aaagctccat
     8881 aaaacgcttg gtgtctgaaa cgacatcagg gtcactcagc aattctccta gttcttcata
     8941 acggtcttct acagcttgta gttgatcata gatgttcatt tttcttcatt ctccttattg
     9001 atttcagggg caaaataatg tttacggcaa accgagatat aggtttcatt accaccaatc
     9061 tggatctgtt ctccatcgta aacgggcagt ccatcctgtg ttcgcaacac catggtcgcc
     9121 tttttcttgc aatactgaca gatggtcttg atttcgtcaa tcttgtctgc taaaagcaag
     9181 agatatttgg aaccttcgaa caattcattg cgaaagtcat ttttcaagcc aaaagccatg
     9241 acgggtatgt ctaactcgtc cacaacacga gctaggtcat aaacatggtg gcgtttgaga
     9301 aactgggctt catcgaccaa aacacagtaa ggtttttctg gtaggtctcg gatatagcca
     9361 aagatatccg ttgtttcctc aatcgcaagg gcagggcgtt tcatgccaat tcgactcgac
     9421 acatagccaa caccgtcacg cgtatccaga gccgaggtca taatcacaac accttttcct
     9481 tgctcctcgt agttataggc cactttgaga atctcaatcg ttttaccaga gttcatggtc
     9541 ccataacgat agtacaactg tgccatgttt cttgcttcac gtccatttct aaatttttgc
     9601 tacattctag tatatcataa ttttcttaag ctttaaacgg caaaatgtgg taaaatggaa
     9661 gaaatcaaaa ctagtggagg aagctattat gccatttgta cgcatcgatt tatttgaagg
     9721 acgcacgctc gagcaaaaga aagctcttgc taaggaagta acggaagcgg ttgttcgcaa
     9781 cactggagca cctcaatctg ctgttcatgt catcatcaac gacatgccag aaggaactta
     9841 tttcccacaa ggggaaatgc gcaccaaata agctagctta agcagaattg cttaggcttt
     9901 ttcaatctcc aagtagcacc cattgaagaa atagtctaaa tttgttacaa tttgaaaaga
     9961 gacttggaaa attccaagaa aagagcaatt aattaaagga aacattatga ttacacgtga
    10021 atttgatacc atcgctgcta tctctactcc actaggtgaa ggggctattg gtattgtccg
    10081 cctgagcgga acagacagtt ttgctattgt gcaaaagatt tttaaaggaa aagacttgaa
    10141 caaggttgcc agccacactc tcaactacgg tcacattatt gatcctctga ctggtaaagt
    10201 catggacgag gttatggttg gggctatgaa gtctccaaag accttcactc gtgaggatat
    10261 tatcgagatt aacacccacg gtgggattgc ggtgaccaat gaaattctcc agctagctat
    10321 tcgtgaaggg gctcggttgg cagaacctgg tgaatttacc aaacgtgctt ttttaaacgg
    10381 tcgcgtagac ttgacacagg cagaggctgt gatggatatc atccgtgcca agactgacaa
    10441 ggccatgaac attgcggtca aacaattaga cggctccctt tctgacctca ttaacaatac
    10501 ccgtcaagaa atcctcaata cacttgccca agttgaggtc aatatcgact atcctgaata
    10561 tgatgatgtt gaggaagcta ctactgccgt tgtccgtgag aagactatgg agtttgagca
    10621 attgctaacc aatcttctta gaacagcccg tcgcggcaaa atccttcgtg aaggaatttc
    10681 aacagctatc atcggacgtc ccaacgttgg gaaatccagc cttctcaaca acctcttgcg
    10741 tgaggacaag gctatcgtaa cagatatcgc tgggacaaca cgagatgtca tcgaagagta
    10801 cgtcaacatc aatggtgtac ctctcaaatt gattgataca gccggtattc gtgaaacaga
    10861 tgacatagtg gaacaaatcg gtgttgagcg ttcgaaaaaa gccctcaagg aagccgactt
    10921 ggttctacta gtgctaaatg ccagtgaaca actgactgcg caagacagac aacttcttga
    10981 aattagccaa gataccaatc gcattattct acttaataaa accgacctgc cagaaacgat
    11041 tgaaacttcg aaactacctg aagacgttat ccgtatttca gtccttaaaa accaaaacat
    11101 cgacaagatt gaagagcgaa tcaacaacct cttctttgaa aatgctggct tggtcgagca
    11161 agatgctact tacttgtcaa acgcccgtca catttccctg attgaaaaag cagttgaaag
    11221 cctacaagcc gttaatcaag gtcttgagct ggggatgcca gttgatttgc ttcaagttga
    11281 cttgactcgt acttgggaaa tcctcggaga aatcactggg gatgctgctc cagatgaact
    11341 catcacccaa ctctttagcc aattctgttt aggaaaataa gaaaaatcca tgatccttca
    11401 ttcggtcatg gattttattg tctttattag taatctggtc ttaagacccc tgttacagtt
    11461 gccttagttg cttcgtagtc gccatctacg acaaccttga taatgcgttt ggcatcttct
    11521 tctggtgctg gaacaagagg tagacgagtg ggtccagctt caaatcccat atagttaaga
    11581 attgccttaa ctggagcagg acttggataa gagaagagag cattaacctt aggaatgaat
    11641 ttacgctgaa ttgctgcggc tttcttcata tcgctttctg caatggcagt aaacatctcg
    11701 tgcatttcat ccccatttgt atgagaggca acagaaataa ccccatccgc cccaaggttc
    11761 atggcatgga aagcatctcc atcctcacct gtataaatca agaactcttc aggcttgtgc
    11821 tcaatcaagt aagccatatt agccaagcta gtacattctt tgacaccgat aatatttgga
    11881 tggtcagcca agcgaagcat ggtttctgga gtcaattcga caactacacg ccctggaatg
    11941 ttatagataa taattggtag gtcagaagca tctgcaatag ccttaaagtg ctgatacatc
    12001 ccttcttgag aaggtttgtt gtagtaagga acaatagcaa gcccagctgc gaaaccacca
    12061 aattccgcta cttctttgac aaactcaata gagtcacgcg tatcattagt acctacaccc
    12121 gcaatcaaag gaacgcgtcc attgacaacc ttttgtacag ccgcaaacaa ctccaactcc
    12181 tcatcgtggg tcaaagttgg actctcagca gtcgttcctg cgagaagaat tccatccgta
    12241 tgatgggcca ataaatgctc aatcaaggct ggaatagcat caaagttaat ggaaccatcc
    12301 tcatggaagg gggtaataaa ggctgtaatg attttacatt cttttaaatc ttgataagac
    12361 acgaaaacac ctctctattt caaagaagga gttcatctga actcctaaac gatatgacta
    12421 ttttaattca aatttcaatt cagctgttgg acgaaccaat ccacgttcat gaagagtttc
    12481 agcaatctga actgagttcc aagcagcacc tttgagaagg ttatctgaaa caacccacat
    12541 gtgaattcct ttttctgcat ccaagtcttt acggatacga ccaacaaagg tatcacgtga
    12601 accaactgca ttgatggctt gaggatagat ttgatgaact acatcatctt caagaacagc
    12661 acctgggaag gatgcgatag ctgctttgac ttcttcaatt ggagccactt cctttgtttc
    12721 aatataaact gactcagagt gagctgacaa gactggaata cgcacacatg tcgcagatac
    12781 tgcaatgcta tcatcttcca taattttctt agtttccttg gtcatcttca tctcttcgta
    12841 cgtgtaatca ttatcagtga agacatcaat ttgtggaaga gcgttaaagg cgataggata
    12901 atgtttcttg tcaccacctg aaggcaagat ttccgcatgc aaatcacgtg gtttcactcc
    12961 atcattcaag acctcacgaa gttcacgttg tgtctcaaga attgctccca taccagcacc
    13021 tgaaacggct tgataagttg aaacaatgat acggtccaag ccccattttt ggcgaaccgg
    13081 ctcaagagcc accatcattt ggattgttga acagttaggg caggcaatga ttccgttgtg
    13141 ggcatcaagt gcatgagcat tgacctctgg aacaaccaaa ggaacatctg gattttgacg
    13201 gaaataagat gtattatcca ctactaccac gccagctttt actgcgtatg gtgcatactt
    13261 agctgatgtc gaaccacctg ctgaaaagag agcaatatca actccttcaa aagctgtttc
    13321 agtcgtttct tcaatcgtaa tatcttgatc tttaaatttc aatgacttac ctgctgaacg
    13381 tgcagaagca aggtaacgga ttttatcgat tggaagtgtt gattcttcca acatttttat
    13441 catctgagca ccgacagcac ctgtcgcgcc gactacagca actgtatatc ccataaataa
    13501 cctctttcgg aattttctaa aaatttctat aatagaagta ttatactact ttttccatga
    13561 attgcaaagc tttttcatca ttttttggaa aataaaaatc cccaatcgct agactaggga
    13621 ttaagaggca tcttcatgtg atgagcaggt tcacacaact catcaaggtc cgctcctgcg
    13681 ttatgacctc cttatgctca atagtagccc gaagactacc tatcgactca tcgcatctac
    13741 tattctacta gatagagtca tttttgtcaa cagccaaaac tctttatact cttcgaaaat
    13801 ctcttcaaac ttcgtcagcg tcgccttgcc gtatgtatgg ttactgactt cgtcagtttc
    13861 atctacaacc tcaaaaacat gttttgagct gacttcgtca gtttcatcta caacctcaaa
    13921 aacatgtttt aagctgactt cgtcagttct atctacaacc tcaaagcagt gctttgagca
    13981 acctgcggct agtttcctag tttactcttt gattttcatt gagtattagt tttatttaca
    14041 caggtgcata agaaatatat tggaaaaatt gggggcagac ataacaaaaa cccttgtaaa
    14101 tcaagggctt ttctgtctat ttaatgctaa ttgccgggat tgaaccggcg acctcatcct
    14161 taccatggat gcgctctgcc aactgagcta aatcagctta cttaagaagt atactatatt
    14221 cagaaaaact tgtcaagttt ccttagaaat tttccatagg aaaaagccag gtaagaacta
    14281 cctagcttat cttcttctat ttacttaaat caattcgacg accaatttta ccaataataa
    14341 tcgctccaat aatcaatgaa gcaaattcac cgattcctgt tgtaaaccaa gtaaggaaga
    14401 atggtaattc tgctacaata tttaactctg cagcgatagt aaacatggaa attgaaaaga
    14461 ggattgaaaa gaagaaatga tcttttcgaa tcaatccgtt aaagaggtaa tccttgctat
    14521 attttgcaaa aagccaaaca cctaaactga ggaatactaa ggttgaacca ccaccaacaa
    14581 agacatctag cagtccgaag ctaaagaaat tagcaatcat acaaccgatg gtaactccga
    14641 tgatgtactt aggattgtaa aaagccataa agttcatcat ttctgaaata cgaaactgat
    14701 aagcaccata gctgatggca tttaggggcg gtgtgacagt caaaacgacg tagatagcag
    14761 cgacgattgc aatatctgca acatcacgaa tagttaattt tttcatcttt tctcctttgg
    14821 cggttatccg cgtgtaatat gcttggtgaa agaagctaag caccaagggt tgattcattc
    14881 aaccttacta gtatagcaca atagcctgct ttatgctata cttaaagcat gaaaaaacct
    14941 attcaaaaat tttttaacaa tgaaatctta gcctatctct tttttggcct tgcgacaact
    15001 ctagtttcga ttctctcacg actagtcatt tatcaactaa gtcatcagga actccttgct
    15061 acggccttgg caaatattat cggtatctta tttgccttta tcacaaatga tacgattgta
    15121 tttaagcaaa aaaagaaaaa tagacttatc cgtttagtga aattttctct tgctcgcctt
    15181 tctacttttc tgttagactt gtttttaact tttctctttg taacccaatt tcctcacatc
    15241 atagggcaat tcgtaactga aaacattgat aagataaatg ctattgaaac aataattgca
    15301 caaatattca ttattatcat caattatatc ttgagcaagg tctatatttt tagaaaataa
    15361 tgctccattt atgagccttt taattgcctt ctataatgat ttaggataca atgaaacacg
    15421 aaacattgaa aggaaaacag tatgttaaaa aatctaaaat cgttcttgct tcgaggaaat
    15481 gttattgacc ttgctgtcgg tgttgtcatt gcctctgctt ttggtgctat cgttacttca
    15541 cttgtaaacg acattatcac tcctcttatt ttaaatcccg ctttgaaagc tgctaaagtc
    15601 gaacgtatcg ctcaactttc ttggcatgga gtcggctatg gtaacttttt aagtgctatt
    15661 atcaatttta tctttgtggg taccgccctc ttctttatta tcaagggcat tgaaaaagca
    15721 cagaaactga ctggcataaa gaaagaaaaa actgccgaaa aaaaaccaac cgaattggaa
    15781 gtccttcaag aaataaaagc tctccttgag aaaaaataat cgattaaaag gatctagcgc
    15841 aaagctaaat ccttttttct ttactctttg ggtaacttgc ctgctttttc aagcattttt
    15901 ttgataagat aaggcatctt aacattctcc cgcccttttt tctcaatcag ttttttcaca
    15961 aattctggca tttgtaaatc ttcagattca gctaaaatgt ttttcgtctc gtctgaagga
    16021 actaactcat caaaggtctc ttcttctggg agaaattcct taaactcttg attttcattg
    16081 actctaactg tattgaccaa agcatcaatc aaacgagaat ctgtatttgg cattggtgga
    16141 cgatggtagt ttaccccaaa ttcctggcat aagtcataac attctacatc attgtcaaac
    16201 aagacctcaa tatgctcact gatgaaacta ataggtacaa aaatataatg gtctggatgt
    16261 tctgtctgtt ctctgagata ctccaaaaca tctggtttaa tccatggaat accaatatca
    16321 ctctcactct gccaagtgtt ggtatattgt tctgaactca agcccagttt ttcagcgact
    16381 agcttgctat tttcgaaaat ttggtctata taaggatcac caaagtccaa ggcaaaaatg
    16441 ggcacactat gggctgaaaa gatgacttta aagctgtctt gctttacttc ttcttttaaa
    16501 atcttagcaa tttcatctgc ccaatagttt aagagcgctt cttcctgata ccagtcctta
    16561 atgaccaaaa attgaatttg tttgctttct aaaaattttt catagcccat gacagagtag
    16621 aaagaataat ggggctccaa aatcaagcaa atacactgtt caattccgtc tgcttccatt
    16681 tgaccgatca catctggaat aaagggactg gaaaacttat tagcaaagta gacactgtat
    16741 tcattcccca gcctagcttc taccaaggca acctcttgac gggtaatttt ttgcagaggc
    16801 gtgcctccaa ttcgtacata attatcatag agagtctgaa tctcgtggtc ttggggtctc
    16861 accccacgac gaatatttgt gaaaaaatca gctacacctt caaaggtaat ctcttctggt
    16921 gaaccgaagg tcatcattaa aattgctttt ttcatgactg cttccttgtg atgtttttat
    16981 caagtttatt ttatcattaa ttaatcgata agtaaacgct aatataggga cattctcaat
    17041 cttctgtctt ttgtttttct cttctttcta tgatacaatg gaaaaaataa attcaaaagg
    17101 agttttttta tgacttatcc aaatctcttg gaccgcttct taacctacgt taaggtcaac
    17161 acgcgctctg atgaacactc tactactact ccaagtacac agagtcaggt tgacttcgca
    17221 acaaatgtcc taattcctga aatgaaacgt gttggactgc aaaatgttta ctatctaccg
    17281 aatggttttg ctattggaac cttgccagcc aacgatccgt ctttaacacg taagattggt
    17341 tttatatcgc acatggatac tgctgatttt aatgctgaag gagtcaatcc acaggtaatt
    17401 gaaaactacg atggtggtgt gattgaacta gggaattctg gtttcaaact cgatccagct
    17461 gacttcaaga gtcttgaaaa atatccagga caaacgctca tcacaacaga tggaacaagc
    17521 ttgctaggtg ctgatgacaa gtcaggaatt gctgaaatta tgacagccat tgaatatcta
    17581 actgctcatc ctgaaattaa gcactgtgag attcgtgttg gttttggtcc agatgaagaa
    17641 atcggtgttg gtgccaataa atttgatgca gaagattttg atgtggattt tgcctacact
    17701 gttgatggtg gtccactagg tgaacttcag tacgagactt tctcagccgc tggtgctgaa
    17761 ttgcatttcc aaggccgtaa tgtccaccct ggtactgcca aagagcagat ggtcaatgcc
    17821 cttcagctag caattgattt tcataatcaa cttccagaaa atgaccgacc tgagttaact
    17881 gaaggttacc aaggttttta ccatctaatg gatgtgacag gtagtgttga ggaggtgcgt
    17941 gcaagctaca tcattcgtga ttttgaaaaa gatgcctttg aagcgcgtaa agcatccatg
    18001 caatctatcg ctgataagat gaatgcagaa cttgggagct accgtgtcac tctcaacttg
    18061 acagaccagt actacaatat gaaagaagtc attgaaaaag atatgactcc aattaccatt
    18121 gctaaagccg ttatggaaga tctaggtatc acgcctatta tcgaaccaat ccggggtgga
    18181 acagacggct ctaagatttc ctttatggga atcccaactc cgaatatctt tgcaggtggc
    18241 gaaaatatgc acggacgttt tgaatacgtt agccttcaga ctatggaacg tgcagttgat
    18301 accatcattg gcatcgtagc ttataaaggc taaaaagacg aggtagctca gctacttcgc
    18361 ctttcttttt attctactgg tttttcttga tttccagtag ttgtagaaga ttctgttgtt
    18421 tcattttctg aagttgattc agcaggttta gaatctcttg tattgcttgg tttgttttcg
    18481 tcgctagcaa tttcaatgtt agattctgca gttgcgtttg gttggttctc agcactggtg
    18541 ttatcactat ttgcttcagc atttcttgct ggacttgttt cttcacttgc gctagctttt
    18601 gactggattt gatgattcaa aactagaata gcttttgtcg attcaagtaa agctgttttg
    18661 tctttactct tagcagaaag ttgatctaat aatgcatcca ccttatcaaa gtccgcatca
    18721 gatccattat tactttctaa ataagagtga agcgacatga gaatatcgta gagtttttga
    18781 tagagtacaa gtgtctgaga atcttgctca gcattttcct tttcttgttg aagggcgcta
    18841 gcgatacgag tcaagacatc ttttacctga ctgtttactt catccaagtc tgcatcagcc
    18901 ttgtttgtgg cagcttttag attttctact tcttctgcca aggattgtct gattccttct
    18961 tcatggattt gttccaagag ttgatttacc ttgctcaaaa gactttctac ttcttccttg
    19021 ctatctgtcg cagattattg gttgccatct accatgtact cctaaaacag gagagttata
    19081 atccaagatt acaaggcctt acagaaataa gaaatccaga taagacaatg ttcgtccaag
    19141 acgctattcg cttcgcacag cagcacggat tcaatatgct ttaattttaa agtttaggtg
    19201 tcaagacctc tttttagtgt gcccaaaatt tagagaagta atcaatcaac taacttttat
    19261 ttttttcaaa ctttcagtaa actgacctaa agctaactca atctgtcttt gtagatgctt
    19321 ctgctatcag ctagaagttg atctactttt gccaagactg ccttctcatc aaaagttcca
    19381 ggttgatagt tggattgcag ggatggaatc ttgtttttca aagccgcttc atatccctta
    19441 gtttgaacct tgatgtagtg attgtggtcg ccatgaggaa tcacaaaacc ttctgaatct
    19501 tcacttataa ttcgattggc atcaaaacca tgaccatctt cttcctcatg atggacatgt
    19561 agtgacggat tacttaatac agaactagaa gaacttccta cctcttccgt gttagagtgt
    19621 gatgggggat tgttaagaga tgacttagga atatagtgat agtgatcccc atgtcttact
    19681 atataagcat cacctgtatc tctgacaata tcattagggt taaagacata tgtggctgct
    19741 aattcacctg ccgacaagtc actctcagga atgaaatgat agtgaccacc atgtggtact
    19801 atagtagatt gaaatagaat atgagcaaat tgataagggg attttaaagt aatttctaac
    19861 aatgatttag aaactatgat gtgctattct aaattcaact cactatatat aaccatcatc
    19921 ggtagtataa cgtccctgta attttgctac agatacttct gcactagctc ctttatcgtc
    19981 tttaccatgt tcttgttttt ggcgattgat ttcatctttt gttcgtacat tttctgcatg
    20041 agcttgatct ttaaggtaaa cataatactt tccatctacc ttaataatat atcctccctt
    20101 aacctaactg acgatatctt gatctttcgg ctgatagttg ggggctttca ttaatagctc
    20161 ttcactaaag agcgcatcaa aaggaacttt accattatag tagtgataat gatcgccatg
    20221 agaagttaca taaccttgat ctgtaatctt aataacaatt tgttttgctt gaattccttc
    20281 tttttgacta acctagtctg gagtcaaatt ttcagtcttc ttagtgtctt tattactgtt
    20341 tacatatgaa acacgatttt tatctgtatt ggcctgttag ctatgttggt tcagagcata
    20401 aacacacaga cttaaggaaa ggataacaac agatccagct gctatatatt tctttttaaa
    20461 tttcataa
//
LOCUS       DAVKBK010000030        18556 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVKBK010000030 DAVKBK010000000
VERSION     DAVKBK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18556
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.030"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            80..268
                     /locus_tag="VWX69_001246"
     CDS             80..268
                     /locus_tag="VWX69_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192592.1"
                     /translation="MSFFAGFGAKLEFTSYNPFLSVKFGLVVALTVFVVQLLAILPAM
                     VKRGNKNENVESNNSCEE"
     gene            231..1622
                     /locus_tag="VWX69_001247"
     CDS             231..1622
                     /locus_tag="VWX69_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEU9192593.1"
                     /translation="MRMLNQTIRVKSKYPYLIRPRNIKIVRLFIQIFVFLLLISSWIA
                     IIPFIARLVFSMFFISLLFFVEKFFRSNFIAKLRNKLNIREALFYMLISLNLYDELDN
                     EVVDTAVLYFDVENNKVVVCAPLFGNRYLKTLKNLEEYLCPTLGLSLLSKKEEIDKIV
                     YVLGQKEEIEQYVFNSNTLTREFFKDIPSSIIKLSNTQKFSLKSNTNLGIYGRTGTGK
                     TIALQWYLFNALAKGCGIADNTYLGIVDGKAADLYRIGELLHEELGEQVAVGSSPQML
                     AQLSRKFIENMDARFKIIKQNSSLNADIYELDELGLVPNFLFVDELASIRDSCGSTKQ
                     GRETWNEILQNLGLIARKGRQAGCHLVLSTQDPNAENIPVELRNQISAVLYLGAPGAD
                     RLKMAFSMCELENVPTVSDRKGEALFYADGLNTVEPVLTIVPFVDLKTKKEFLNVVRN
                     ILPTNDGLPPLAK"
     gene            1878..2297
                     /locus_tag="VWX69_001248"
     CDS             1878..2297
                     /locus_tag="VWX69_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192594.1"
                     /translation="MVYNMTDTNIKIGLLDLEMSQFDIPKKVVILSVRVNNKYKEVNG
                     ENVKTDEVSKITSAVLDADKVKVLTEMGISTDDLKAINLEIIGNLDKIAKLAQNDALL
                     NVPVELIRPKVRLAWNMARNNWSGVKIVCEDIKVLGE"
     gene            2302..3321
                     /locus_tag="VWX69_001249"
     CDS             2302..3321
                     /locus_tag="VWX69_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU9192595.1"
                     /translation="MNTVRIDYFAVTVKNISPEKVLTDILLIPLENFTLNDWGINKYK
                     QHYSCSEIKVYFNADRLSMGVFIELKGQGCRQYEEFLNSNENNWIALISRLYHHNANF
                     TRLDIAHDIFDGSLDVQRIYDYCKKGLCISKAKHFEYHEKSVLDSGERVGETVAIGSR
                     GNQQWCIYNKRMEQLGKQELVEVSSWTRAELRCWQEKANIIAEQLYLKRPLSSIYFEA
                     INGHYRFIRPNAIDSNRWRRKKVEWWVNYLGTENQTVLSITRAKTTLRESEVWTEKQV
                     AKTLAKVYIAKYQAYDVQKAEDYIQNLLKEGLSKLTDNDEKDIEQYIREQNSSQLWGT
                     DGRSD"
     gene            3325..3507
                     /locus_tag="VWX69_001250"
     CDS             3325..3507
                     /locus_tag="VWX69_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEU9192596.1"
                     /translation="MADTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVKELLGMEL"
     gene            3509..4636
                     /locus_tag="VWX69_001251"
     CDS             3509..4636
                     /locus_tag="VWX69_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9192597.1"
                     /translation="MAYIEYKQRGKKRLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSCIRASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHAESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(4719..4791)
                     /locus_tag="VWX69_001252"
     tRNA            complement(4719..4791)
                     /locus_tag="VWX69_001252"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4756..4758),aa:Lys,seq:ctt)
     gene            complement(5056..6327)
                     /locus_tag="VWX69_001253"
     CDS             complement(5056..6327)
                     /locus_tag="VWX69_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU9192598.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            6597..6797
                     /locus_tag="VWX69_001254"
     CDS             6597..6797
                     /locus_tag="VWX69_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192599.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            7001..7180
                     /locus_tag="VWX69_001255"
     CDS             7001..7180
                     /locus_tag="VWX69_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192600.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            7317..7496
                     /locus_tag="VWX69_001256"
     CDS             7317..7496
                     /locus_tag="VWX69_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU9192601.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            7533..7985
                     /locus_tag="VWX69_001257"
     CDS             7533..7985
                     /locus_tag="VWX69_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU9192602.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            8276..8746
                     /locus_tag="VWX69_001258"
     CDS             8276..8746
                     /locus_tag="VWX69_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU9192603.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            8765..9853
                     /locus_tag="VWX69_001259"
     CDS             8765..9853
                     /locus_tag="VWX69_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU9192604.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            9834..10262
                     /locus_tag="VWX69_001260"
     CDS             9834..10262
                     /locus_tag="VWX69_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9192605.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            10400..11350
                     /locus_tag="VWX69_001261"
     CDS             10400..11350
                     /locus_tag="VWX69_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU9192606.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            11352..12095
                     /locus_tag="VWX69_001262"
     CDS             11352..12095
                     /locus_tag="VWX69_001262"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU9192607.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            12106..13902
                     /gene="pepF"
                     /locus_tag="VWX69_001263"
     CDS             12106..13902
                     /gene="pepF"
                     /locus_tag="VWX69_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9192608.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(13962..14639)
                     /locus_tag="VWX69_001264"
     CDS             complement(13962..14639)
                     /locus_tag="VWX69_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9192609.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQKKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEQGKEF
                     LEKEWGI"
     gene            14886..15656
                     /locus_tag="VWX69_001265"
     CDS             14886..15656
                     /locus_tag="VWX69_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192610.1"
                     /translation="MLYLLGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDFLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            15649..16413
                     /locus_tag="VWX69_001266"
     CDS             15649..16413
                     /locus_tag="VWX69_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9192611.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            16838..17629
                     /locus_tag="VWX69_001267"
     CDS             16838..17629
                     /locus_tag="VWX69_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU9192612.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLVFTSF
                     AKEIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSILFTDDEDWRLARVVYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            17740..18408
                     /locus_tag="VWX69_001268"
     CDS             17740..18408
                     /locus_tag="VWX69_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU9192613.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFANKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLIIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         5540 a         3159 c         4196 g         5661 t
ORIGIN      
        1 aaaatttgaa aggaaaaata caaaaatgaa aattaatgaa tatttatgga gaacgagctg
       61 tcttatactg ctaattatca tgagcttctt tgcaggcttc ggagctaaat tagagtttac
      121 atcttataac ccgtttttat ctgttaaatt tggtttggtc gtagctctga cagtctttgt
      181 agttcaattg ttagccatac tgccagccat ggttaaaaga ggaaataaaa atgagaatgt
      241 tgaatcaaac aattcgtgtg aagagtaaat acccttactt gattcgtccc cgaaatatta
      301 aaattgtaag attgtttatc caaatttttg tctttttact cttaatatct tcgtggattg
      361 ctataatccc atttattgct cgtctagtct tttccatgtt ttttataagt cttctttttt
      421 tcgtagagaa gttctttcgt tctaatttta tagcaaaatt gagaaacaag ctcaatatca
      481 gagaagcctt gttttacatg ttaattagtt taaatttata tgatgagctc gataatgaag
      541 tagtagatac agcagtttta tattttgacg ttgagaataa taaagttgtt gtctgtgccc
      601 cactatttgg gaaccgttat ctgaaaacct tgaaaaattt agaggaatat ctctgtccca
      661 ctttgggctt gtccttgctg tctaaaaaag aagaaatcga taaaatagta tacgtgttag
      721 ggcagaaaga agaaatagaa caatatgttt ttaatagtaa cacattaaca agagaatttt
      781 ttaaagatat tcctagttca ataatcaagc tgtcaaatac acagaaattt agtctaaagt
      841 ccaacactaa cctaggtata tatggaagaa cggggacagg caaaacaata gctctgcaat
      901 ggtacttatt taacgcactg gctaaaggtt gtggtattgc tgataatact tatttaggca
      961 tagtagatgg taaggcagct gacttgtatc gtattggtga acttcttcac gaagaactgg
     1021 gagaacaagt ggcagtaggc tcttcaccac aaatgcttgc ccaattatcg agaaaattca
     1081 ttgagaatat ggatgcaaga tttaaaatta tcaaacagaa tagttcattg aatgctgaca
     1141 tttatgagct agatgagctg ggactggtac ctaatttttt gttcgttgat gaactcgctt
     1201 ctattcgtga tagttgtggc tctacgaaac aaggtagaga aacatggaat gaaattctac
     1261 aaaatttagg cttgattgca cgcaaaggac ggcaggcagg ttgccaccta gtcctatcta
     1321 ctcaagaccc taatgccgaa aacatccccg ttgaattgag gaatcaaatt tcagcagttt
     1381 tataccttgg tgccccaggg gctgatagat tgaagatggc ttttagcatg tgcgaattag
     1441 aaaacgttcc tacagtttca gatagaaaag gggaggctct cttttatgct gatgggctta
     1501 atacagtaga gccagtgcta acaattgtgc catttgttga tttaaaaact aagaaagagt
     1561 ttttaaatgt agttagaaac atactgccaa ctaatgacgg tcttcctccc ctagcgaaat
     1621 agggcgattg ccggaggcag aatcgagcgg agcgctctct tttcgctagg ggagggagag
     1681 ccaaccgact gctttgcagg aggtcagaaa aaacatcccc agtactaata gggggtgcac
     1741 acatacatga aatgtactct aaacccttga tacgtgaggg gttacggctt actagttgca
     1801 ccaaggggtc gcaaactctt gggagagtag ggatgagagg tgtttccatg tatgatacgg
     1861 aattaaagga gaaaaatatg gtttacaata tgacagatac aaacattaaa attggattgc
     1921 ttgaccttga gatgtcacag tttgatattc ctaagaaagt agtgatttta tcagttaggg
     1981 tgaacaataa atacaaagaa gtcaacggcg aaaacgtgaa gacagatgaa gtaagtaaaa
     2041 ttacttctgc tgttcttgac gctgacaaag tgaaagttct aactgaaatg ggaatttcta
     2101 ctgatgactt aaaagctatt aacctagaaa ttatcggaaa tctagataag attgcaaaac
     2161 ttgctcaaaa tgatgctttg ttgaatgttc ctgttgaatt gattcggcct aaagttcgac
     2221 tagcttggaa catggctagg aataattggt ctggtgtaaa aattgtgtgt gaggatatta
     2281 aagttctagg agaataatcc tatgaataca gttagaatag attattttgc tgtgacagtt
     2341 aagaatattt cgccagaaaa agttctgaca gacatccttt tgattcctct tgaaaacttt
     2401 accttgaatg attggggcat aaataagtat aagcaacatt attcttgttc agaaattaag
     2461 gtgtatttta atgctgatag gctttctatg ggtgtattta ttgaattaaa agggcaaggt
     2521 tgtcgtcaat atgaagaatt tttaaacagt aacgaaaata attggattgc tttgataagt
     2581 cgtttatatc atcataatgc caactttact agactagata ttgcccacga catatttgac
     2641 ggtagcttag atgttcaacg aatatatgac tattgcaaga aaggattatg tatctcgaaa
     2701 gcaaaacact ttgaatatca tgagaaatca gttctagatt ctggtgagcg tgtaggagaa
     2761 acagttgcaa taggttcacg aggtaatcag cagtggtgca tatataataa acgcatggag
     2821 caacttggta agcaagagct tgtagaagtt tcatcttgga ctcgcgcaga gcttagatgt
     2881 tggcaggaga aggctaatat aattgcagag cagttatatt taaaacgtcc cttatcgtca
     2941 atatattttg aggctatcaa cggtcattat cgctttattc gtccaaatgc tatagatagt
     3001 aatcgttgga gaagaaaaaa ggttgagtgg tgggtaaact atctagggac agaaaatcag
     3061 acagttctga gtattacaag ggctaagacg acgttacggg agtctgaagt ttggactgag
     3121 aaacaggttg caaaaacatt agcaaaagtc tatattgcaa agtatcaggc ctatgatgtt
     3181 caaaaggcgg aagattatat tcaaaacttg ctcaaagagg gactttcaaa gctaactgat
     3241 aatgatgaaa aggatataga acaatatata agagaacaga atagttccca actttgggga
     3301 accgatggaa ggagtgactg acatatggca gatactatat caaataagga tttgatttcc
     3361 atgggctata ggccatcaac agctaatgct attatccatc aggcgagaga attacttgta
     3421 tcacgaggct atacatttta taatcgcaaa cgtttgatgg ttgttccaaa aagtgttgtg
     3481 aaagagttgt tgggaatgga attgtgaaat ggcttatatc gagtataaac agcgtggtaa
     3541 gaaaagactt tggtccttct ctatacgaga aaggagcaag agcctactcc ataaaagcgg
     3601 atttaaaaca aaacgagaag ctaaaataga agcggagaaa gttcttcata agttaaatac
     3661 tgggagtgtc ttaagctcta gtatgacttt atcggagctt tataatgaat ggcttgattt
     3721 aaaaatttta cctagcaata gaagtgtagt tactaaaaaa aaatatctca tgagaaagaa
     3781 ggtcatcgaa aggttatttg gaaataagcc tgtatcacaa attaagccta gcgagtatca
     3841 aaaaattatg aatgagtatg gagagactgt atcgagaaat ttcttaggaa gattgaattc
     3901 ttgtattcgg gcaagtatac agatggctat tgctgataag gtgataatag aggattttac
     3961 tgcttatgtt gagttgttct cttctaagag tggacaaaag gttgaggaaa agtatttgca
     4021 tgctgagtca gattatcaaa aagttttagt atatttgaaa aataagtttg attatcaaaa
     4081 atctattgta ccgtatgtaa tttatttcct ttttaaaact ggcatgcgtt tctccgaatt
     4141 gattgctcta acttgggatg aagttgacga gcttaatgag caacttaaaa cttatcgtcg
     4201 ttacaacacc gctattcata agtttactcc acctaaaaac aatacttcaa taagattagt
     4261 tcctattact tcagatatgc tttccttgtt aaaaacattg aaaatattgc aattaaaaac
     4321 aaataaagaa ttaaatattg ataatgaaaa taatttgatt tttcagcatt ttggctatgt
     4381 ctacgatgtt ccagatattg caacagtcaa taaagctata aaagtaatgt tgaaggaatt
     4441 gcaaattttt ccattgatta ctaccaaagg agctagacac acttatggta gttatttatg
     4501 gcataataat attgatttgg gagttatagc gaaaatttta ggacataaag atatctccat
     4561 gttgattgac gtttatgggc ataccttgga ggaaaaaatt agtgaagagt ttatggctgt
     4621 gaaaagtttg ttgtaaaaac acggcaaatt gcacgacaat ttttaaaagg aaggcaaaaa
     4681 aagccctata ttataaggct tttcctgttg tatttatatg ccccctacag ggatcgaacc
     4741 tgtgacccac ggattaagag tccgctgctc tgccagctga gctaaggagg caaagaaaaa
     4801 agctgtattg gtgccgaaac ttcacggttt gtattgaacc cgcgcaatta agcaggtggg
     4861 caactcgctc taactgaagc tgtttccgtg tgagacggcc tacatgctgt tagaagactt
     4921 ttgtttccct aataatacaa aaaatagtcg gtcaacactt aagtgtgaag tcgtacacca
     4981 cagcgtttct atacttatat gataccactt tttcaaaaaa aatcaagagg aaagtgcaat
     5041 tttttgaaaa ggatttcaga tttttcgcaa acggtcgata gcttcctttc tttgagccaa
     5101 agcccgttca tatttaccag tatcttctgc ttggaaatag tgatgattac gaattttttc
     5161 tggcagatag tcttgcttga cccaatttcc aggatagttg tgtggataga gatagtcttg
     5221 ggcattcccc agttccttgc ttccactgta gtgcccatca cgtaggtgtc gcggaatagg
     5281 caagtgccct gatgttttga ggtcagcaag tgccttatcc atagctacat aggctgagtt
     5341 ggattttgga gaaagggcca aatcaatcac gacattggca atgagaatgc gggcttctgg
     5401 gaacccaatc ttctgggcag catccagagc agtcacggta tgaatctggg cctcaggatt
     5461 ggctaagccg atatcttcat aggcgataac agtcaagcga cgagcgagac taggcagatc
     5521 cccagcctca atcaagcggg cagtatagtg gagactggca tccacatctg agccacgaat
     5581 agacttttgc agggcagata gaacatcata gtgaccgtct ccatccttgt ccatagtgat
     5641 gtagcttctc tgaagactat tttccatgat gtctaaggtg atgtggcgaa tgccctcgtc
     5701 attctcaggg gtagagagaa cagctaagtc cagtgagtta aaggcagagc gaaggtctcc
     5761 gtttgtagag gttgcgatga aatccagcgc atcctcatct agttctattg gaaaatcaaa
     5821 accacgttca gggttactta gagctatctg cagggcctct ttgacgtctt ggttagacag
     5881 aggttccaac tcgaaaattt gaactcggct acgaatggca ggagtgacag agaagaaagg
     5941 attttcagtc gttgctccaa tcatgatgac cagtccactt tccaagagag gcaagaggaa
     6001 gtcttgcttg gtcttatcta gtcgatgaat ttcgtctagc aataggacga gaccaccaga
     6061 aaatttagct tcttccgaga tttcttgcag tcgcttttta ctatcaactg tcgcattgaa
     6121 agttcgaaag gcatacttgg tcgttccagc gatggcagag gcaatactgg ttttgccgat
     6181 tccaggaggg ccatatagaa tcatggagga caggcggttg gcttccacca tgcggcggat
     6241 gatttttcca ggtccgacca gatgctcctg accgatgacc tggtcgatgg ttttagggcg
     6301 catgcgaagc gcgagattgt ctggcatagc agtcctttct agcgtggatt tgagtagaat
     6361 gactcatcta ctatatctta ctatgtccat tctagcctat tagttgtgat atttcaatgg
     6421 ttttgtaata atcagggagt gagatagaat cttttttact atttaattta atgaggagag
     6481 gtatcagcat gagagatttg attttcctta aagctcaaaa taggatagtt gagcctaaag
     6541 aagtggaagt gctgacttga gaaataatat tgctgaatgt cattgtatga actataatga
     6601 aaagagaggt gataagcaat ggaaatgatg gaccaagtca ggaaattttg atttttacaa
     6661 aacaaattcg tcattggatt cttagtgatc aagttatttc agggaaaaga aaacttttct
     6721 tccgggaaga tactccaaaa gagattttag atttgtacga aaacattaaa tctaaacttg
     6781 attttgctta ccaataagtt tattctaata atgggttgaa aaaatatgaa aaatagaata
     6841 attgatgttt ttgaagtagt aaatcgcatc cttgtaataa ctgttgaaaa tcctgatttc
     6901 gaagacttga gagttaatca tactcaatga aaatcaaaga gcaaactagg aaactagccg
     6961 caggctgtac ttgagtacgg taaggcgacg ttgacgtggt ttgaatttga ttttcgaaga
     7021 gtatcagttt gtaaaaattg gagataaaaa atatagagta cgcagtgttc ctatgattca
     7081 ttcaactccg cctcaatctg tcttagatcg agatactttt acaattgact atacagatga
     7141 tgaattgctc gataaagaag cagtttttac tactcattag aaaaataggt ctgaataaat
     7201 tggcttccct tagaaccaca tctaggggct tttatgtata atagaataat aagtatcact
     7261 cctttacaat acgtgtaaca cgtgttataa tggtgttgtc aggaggtaaa agcgctatgc
     7321 ctatgacaca aaaagagatg gttaaactcc ttacggccca tggttggata aagactagag
     7381 gcggtaaagg ctcccatatt aaaatggaga agcaagggga aagacttatc acaatccctc
     7441 atggtgagct gaataagtac actgaaagag ggataagaaa gcaagctggg ttgtaaaatt
     7501 cagcccctgt tttttgatat ggaggtagtg aaatgttagt tacgtatcca gctttatttt
     7561 attatgacga cacagacgga acagaagcga cttattttgt ccatttccca gattttgaat
     7621 actcagctac acaaggagag gggatttctg aggctttggc tatggggtcg gagtggctag
     7681 ggataactgt tgcagatttg atagagagtg atggagagtt acctcagcca tcagatatca
     7741 atagcttgtc tttaattgat aatgatcctt ttaaagatga tgaagatttc gtgtcaacct
     7801 atgaccttga taaatctttt atttctatgg tatctgttga tgtatcagaa tacctaggaa
     7861 gtcaggaacc cataaaaaag actttgacca taccaaaatg ggcagataag ttgggacgag
     7921 aaatgggact taacttttct cagactttga cagacgctat tgcagataag aaagttcaag
     7981 cctaagatta agcgtggtat cgtggtaata gtcaataaaa aagcacgtcc acttgtgcta
     8041 gttactcgcc tattgatttt atagatttat tagccctttc gcgggctttt tatattgatt
     8101 tttatgagaa atgaagaaat cagactttta agaaaatcac tgataccaag ggtttaaatg
     8161 aggtaatatg gtataattag gacataaaat aattttgtgg taagatggta gtatctattt
     8221 tagcatattt ccgagcaatc ggggcgatta aagagtcgca tagaaagagg acaaaatggc
     8281 aacatacgga tttttagatg ttttagagga agagttggac aagaactttc cctttgactt
     8341 tgagattagc tgggacaaac gcaaccatgc ggtagaagtg agttttctat tggaagcgca
     8401 aaatgctgca ggtgtggaga tggtggatga agacggagag gttttatcag atgacattct
     8461 ttttgaggaa gcggtccttt tctacaatcc tgccaagtca acagtcaatg aggaagacta
     8521 tttgactgtt attccttacc tgcctaaaaa aggattttcc cgtgaatttt tagcttattt
     8581 tgcgcttttc cttaaagata ctgctgaggt tgggctagat gtcctcatgg actttttgga
     8641 agacccagaa gcagaggaat ttgtcatgga atggaaccaa gaagtctttg aagaaggaaa
     8701 agttggcttg gaagagggag aattttatcc ttatccaaga tactaggagt tggttggagg
     8761 tgttatgaag aaaattggga cttatttggt ttatgtgcta gcttttgtct ttattatgct
     8821 agcttttgct tgtggaacaa tcgcatttgc agagttgggg tattccgcag ttttagcctt
     8881 tacttttggt tatgccttcg ctcttctaag catgtattta atctttattc ttcatgagct
     8941 gggtcatgct ttttgtggct acttgacagg ctatcggctg gtggcttttg gattaggaca
     9001 ttttattttg accaaaaagt caggcaggtt tcatcttagt agaacagcca ttctgaaaaa
     9061 tgttggtgct caatacattg gtttaaaaga ggatgaaagc gatcaaagaa tcatcctgat
     9121 gctttcagga ggcttgatgg ttcatctcgg cttgatatta ttggcgatag tgtttggatt
     9181 tttgacaaga agctggtatt ttgcagggac ttggattttt cttaatttat ctttcttcct
     9241 aaataacatt ttgccagtcg acatcaccga tggagcaaaa atttgggaat tactacaaca
     9301 ccctgaaaat accaaatacg cctacctggt attgagacat tctgctcaaa ctttgctggc
     9361 tcctcaagaa tatgatttga aagactttgt tcaagcagtt cctgaggatg cacgagggag
     9421 ttttgcggat ggtgtattag gtatgcaagg tgaagtttcc attttggaag ggaaggaaga
     9481 agtagctaaa cagcagtttc aagcattact tgagaggaca actactccga tgatgcagac
     9541 agttgcccaa ctatccctgc ttcatatcgc cttgttggaa ggagattttg agcaagcgga
     9601 gcaatatgct agtattcgac aggtcaaatc gtttctgtct ctcaaactgt ccaatcttca
     9661 agtgatacaa gcttggtatc aatttaaggt aaagaaagat gtagatcgaa ctcgtaaggc
     9721 tctcaagatt gctagacaga aaatggatag tagtcgaatg ttgagggacg agaaacgcta
     9781 ttatgaaaac ttgttagcag agctggaaaa ggaaatgtta gaaggaactg aagatggaac
     9841 tagaaatttc tgatttccca ggctgtaaga ttgctttgtt ttgtggggat aagctcttga
     9901 ctatcttacg tgatgataag gcaagtattc cctgggccaa tatgtgggaa ctgccaggtg
     9961 gtggacgtga aggtgatgaa agtccttttg agtgtgtagc gcgtgaagtt tatgaagaac
    10021 tgggcattca tctgactgaa gattgtctgc tttggagtaa ggtttaccca agtatgcttt
    10081 ttgcagacaa acagtccgtt tttctagttg gtcagttgac acagaaccag tttgacagta
    10141 tcgtatttgg agatgaagga cagggctatc agctgatgaa tgttgaggaa tttcttagtt
    10201 ccagtcaagt tgtccctcag ttgcaagaga gattaaaaga ttatttaaaa gtaagtgatt
    10261 agaaaggatg gttcagttaa atttctaaac tgaacccgcc ctaaacactg tgccaaaaag
    10321 ataaacttct cttagacaca agcgtcttca gagaatttcc tattttggtt ttgtgtttta
    10381 cgggcttggt atcttaataa tggaaacatg gcaagagtta aaagttacag tgaagcgtga
    10441 gggagaggag ttggtttcca atctcttgat tgagctggga gcgcaaggag tcgcaatcga
    10501 agacagtatg gactatgtgg gaaatgttga ccgctttggc gagattttcc cagaggtgga
    10561 gcagcaagaa gaaatcgttg tgacagccta ctaccctgac acggtggatg tgacagtggt
    10621 tgaggcggac ttgcaggctc gcatatcaga attgacggat tttatggatt tgggagagtt
    10681 aaaaataggt acgactgcct tggctgagga agactgggca gacaactgga agaaatacta
    10741 tgagccagct cgtatcactc atgatttgac catcgttccc tcttggacag actatgaggc
    10801 gactgcggga gaaaaaatta tcaagctgga tcctggcatg gcttttggta ctggaaccca
    10861 cccaactacc aagatgagcc tttttgcctt ggaacaggtt cttcgtggtg gcgaaacggt
    10921 gctagatgtg gggactggtt caggggttct ctctattgcc agctcgcttc tgggggctaa
    10981 agaaattttc gcctatgacc tggatgatgt ggcggttcgt gtggctcagg aaaatattga
    11041 gctcaaccct ggcatggaaa atatccatgt agcggctgga gatttgctta agggtgtgga
    11101 aattgaggca gatgtgattg tggctaatat cttggcggat atcctcattc atctaataga
    11161 cgatgcctat cgtttggtta aggacgaagg ctacctgatc atgagtggca ttatcaagga
    11221 caagtgggac atggtgcgcc agtcggctga gtcagctgga tttttcctcg aaactcacat
    11281 ggttcaaggg gaatggaata cctgtgtctt taagaaaacc aaggatatct ctggtgtgat
    11341 tggaggctag catgcagcag tattttgtaa aaggcagtgc tatctctcct gtcactatcg
    11401 aggacaagga aaccagtaag catatgtttc aggttatgcg cttgaaagaa gaggatgagg
    11461 ttaccttagt ctttgatgat ggcatcaagc gcttggcgcg cgtgctggat atggaaaatc
    11521 gtcagtttga gttggtccaa gaattaaatg acaatgtgga actaccagtc caagtgacca
    11581 tcgcatctgg atttcccaag ggagacaagc tggagttcat cgctcaaaaa gtaaccgaac
    11641 tgggtgctag ccaaatctgg gcctttcctg cagactggtc agttgccaag tgggatggca
    11701 agaaattggg taaaaaagtt gaaaaactag aaaaaattgc ccttggagca gccgagcaaa
    11761 gcaagcgtaa tattgtacca agtattaaac ttttcgagaa aaaagcagat tttctagctc
    11821 agctggacca gtttgacttt atcatagtag cctatgaaga atcagctaaa gaaggagaag
    11881 ccgctgcgct tctgcaagca gtcactggtc ttgaaacagg agccaaactg ctctttatct
    11941 ttggtccaga aggcggtctc tcacctgcag aaatcgaaag ttttgaagct aagggagccg
    12001 ttttggtagg cctaggtcct cgtattttgc gagcagaaac agcaccgctt tacgccttat
    12061 cagcccttag tgttttagta gaattagaga aataagagga agaaaatgga acaaaaacac
    12121 cgttcagaat ttccagagaa ggaactctgg gacttaacag ccctatacca agaccgtgag
    12181 gatttcttgc gtgcaatcga gaaagctcgt gaagacatca accagtttag ccgtgattac
    12241 aagggcaatc ttcacacttt tgaggatttc gagaaggcct ttgcggaatt agaacagatc
    12301 tacattcaga tgagccatat tggcaactat gcttttatgc ctcagacgac ggactatagc
    12361 aatgacgaat ttgccaatat tgcccaagct gggatggaat ttgaaacaga tgccagcgta
    12421 gccttgacct tctttgacga tgccttggtg gtagcagacg aggaagtctt ggaccgtttg
    12481 ggtgaattgc ctcacttgac ggcagctatt cgtcaggcca aaatcaaaaa agcccactat
    12541 ctaggggctg atgtggagaa ggccttgacc aatctcggtg aagttttcta tagtccgcag
    12601 gacatttata ctaagatgcg agctggggat tttgaaatgg ctgactttga agcccatggc
    12661 aagacctata aaaacagctt tgtcacctat gagaatttct accaaaatca cgaggatgct
    12721 gaggttcgtg agaaatcctt ccgttccttc tcagagggac ttcgtaagca ccaaaatacg
    12781 gctgcagcag cctatctggc tcaggtcaag tctgaaaaac tcttggctga tatgaaggga
    12841 tacgactctg tatttgatta tcttctagct gaacaagaag tggaccgtgt catgtttgac
    12901 cgccagattg acctcatcat gaaggacttt gcaccagtcg ctcagagata cctcaagcat
    12961 gttgccaagg taaatggtct tgaaaagatg acctttgcag actggaaatt ggacttggac
    13021 agcgccctga atcctgaagt gactattgac gatgcctatg atttggtcat gaagtcggta
    13081 gaacctttgg ggcaagaata ttgtcaggaa gttgctcgtt accaagaaga gcgctgggtg
    13141 gactttgctg ctaacagtgg caaggattcc ggtggttatg cggcggaccc atatcgcgta
    13201 cacccttatg tactcatgag ctggacaggc cgtttgagcg atgtctatac cttgattcat
    13261 gaaatcgggc attctggtca attcatcttt tcagacaatc accaaagcta tttcaacgcc
    13321 cacatgtcga cctattatgt tgaagcaccg tcaaccttca atgaattgct actcagtgat
    13381 tacttagaga accagtctaa tgacccacgt caaaaacgct tcgctctggc tcatcgcttg
    13441 acagacacct acttccataa ctttatcacc cacctcttgg aagccgcctt ccagcgtaag
    13501 gtgtatacat tgattgaaga aggggagacc tttggagcaa gcaaactcaa cagcattatg
    13561 aaggaagttt tgacagattt ttggggcgat gccattgaaa tcgacgacga tgcagctttg
    13621 acttggatgc gccaagctca ctactatatg ggcttgtata gttacactta ctctgctggt
    13681 cttgtcatct cgacagctgg ttaccttcat cttaaaaact cagaaactgg agctgaagac
    13741 tggctcaatc tcctcaaatc aggtggtagc aagacaccac ttgagtcagc catgattatc
    13801 ggtgctgata tttcaacaga caaaccactc cgtgatacca tccaattctt gtctgacaca
    13861 gttgaccaga ttatcgccta cagtgctgag ttgggggagt aaggggatag agaggttgtt
    13921 atagaatggg tatggacagt tatttgctta aaagtccatg tttaaatccc ccattccttt
    13981 tcgaggaatt ctttgccctg ctctgtaatg gtaagtgaac gtggcgtttg tgcagggatg
    14041 accaattgtt tttcactgaa aaattctaaa agagcattgc cgagagctcc gccgacatga
    14101 tttttacgtt cgctccaatc caaacattta gggcaaaatt tccgtttttt ctttttcaat
    14161 tcatccgtat caatgtgtaa ttttttttgg aaataagact tcccagcttc agtgagttgg
    14221 aagtcttttt ctgattcgct gaggagattt tcttgcaaga gataattggt aatggaaatg
    14281 ccaagctcac cagcaatatg gtcatagcag gtgcgagcga cctttaattc ctttttgtga
    14341 atgtgttgtt tataactttt gacatcacgc tgaggagagt agaagctgag aaattccagc
    14401 atttctgcaa tggcagcact ttttaaagaa taataatgaa aacgtccata ggtttgtaga
    14461 gtggttacct gcgcttcggt aagtaatttg aggtgatagc tgacagtatg ttgcttgatt
    14521 ttggtaaagc tggcaatttc gttaaccgtg tgagcttttc catccattag aatatctaaa
    14581 atgtgcatcc gagaagggtc tgataagagt tttgtgatga tgaaaatatc tggttccata
    14641 aaaattttct ccaaatttca tatatcgatt attttctatc ttttattata ctataatcaa
    14701 agcacaagaa aaatagattt taaaaatgtt ttactagaga atattttaaa ttttattgtc
    14761 tgagtttaaa tggaggtaaa attacaaaag taattgcagc agtatccaca gttgaaggac
    14821 gttaatctta agattacatt ctcaacattt tttcaaaagt gagatgaatt aacaaagtat
    14881 ccaacatgct ctatttgttg gggaaagaaa gagtgaagaa gttaagtgtt aaaaatctaa
    14941 aaaagcaata tggttcttat gaagctgtca agggaattag ctttgaattg ggagaaggag
    15001 agtgtttggg tatcttggga atcaacggtg ctggcaaaac atccacttta aagatgattt
    15061 actcactgac ctcaatttcc tcaggagaga ttgatatctt ggggcaaaat attgaaacca
    15121 atcgtcgtaa gagtaaatct tgtctgggta ttgtagggca ggaggatatg ctggatatga
    15181 ccttgaatgt ttatgataat ctttttgctc acggtctatg ttatggtatc tcatctgtcg
    15241 aacttaggaa gagaatcgat tttctcttgg attttgttca actgagcaaa catgcgcaaa
    15301 agatggtgaa tcagctgtcg ggtgggatgc gacgacgtct tgtcttggca agagctctca
    15361 tcaatcggcc tgatattatc attttagatg aaccgacagt tggtttagac attcaatccc
    15421 gcaatattat ttgggataaa cttttggagt tgaaggaatt aggtgtttcc atcattatta
    15481 cttcccacta tatgaatgag attgaatatt tgacagatag ggtgctgatg ctccaccaag
    15541 ggactatcaa agaagaagga actgtagaag acttgctcat caagtatgat gctgacaacc
    15601 ttgagacgct ttttttgggg ttgactggga cagagaagga ggacttgcat gtttaagtta
    15661 tcatttcact ccatcggaca cgttgtggta cgcaactaca tgagttttag aaatttattt
    15721 aaaatttcaa ttgtccccaa ccttatcgac cccctctttt atcttttagc aatgggattt
    15781 ggagttggtg cttatttgac gcatgttaac ggtatgctct accgtgattt tgtcattaca
    15841 ggtttaattg ctgcgactgc catgtctgcg gccactgcag aaacaacggt caatgccttt
    15901 atccagtata agattgaaaa gacttatgat gctatgttga tgacgccaat caatacgaat
    15961 gatattgtgg tgggtcaggc tatctgggca ggtattcgtg cagtgatttt cggtgggatt
    16021 ttttggctga tttccatgct tatcacagcg cattttcatg tcttgatgtt attgattcct
    16081 ctgattttat ttatagtggg ttatttgttt ggtgttttgg gactaatctt tacctacttg
    16141 gcgccgtcta gggaatttct gaattactac aatgttttgg taatccgtcc tctttatatg
    16201 ttttcagata ccttctttcc cattacttcc ttgcccccaa tacttggtga tttgacttgg
    16261 ttttctccct tgtatcacgc tacccgcatg attcgtatta tatggggagg tgaggtgaca
    16321 ggtttgtatc ttcatcttat ctggttgata gccttggcgc tcttgataac ggtgcttcct
    16381 atgtatatgt tacatcgtag atattataga tagtctaatt atttgtgatg ttgtagtcat
    16441 attctaattt atactaaacg ttattcgaat ttggacaggt atgggaactg tgcctatcaa
    16501 tattgtaatt tatggaagtt gaaatagtac ggttcagttt ttaaaatatt gttagaaatt
    16561 gttttaaatt ccctaatcaa tttgtatagt ttttatttca ctttattata actagttttt
    16621 cgcaattttt gagacaggaa tgtgattttt gtgataaggc tctatcatta caagttcatt
    16681 tgtggtcata tggaataaat catttatata tcttttcaga aatatgctgt ttctctgaat
    16741 ataaatgtct ttttcttttt aacttaattt tacaaattgg taaagtcatt taagactgcc
    16801 tttttgaaca gttgctagaa atgtagaggt attgaccatg tatcaagatt tactaagaaa
    16861 aatagcagaa gaaaaaccaa attataacca ggaagaaatc cagtggttgt ttgatcattt
    16921 gggaaatcct tctccagaaa ttcgtgatga ccttgttttt acaagctttg ctaaggagat
    16981 tcaggaagag ctatttacac aggaacaatt tcatttcatt gctgaggtgg tcttagctga
    17041 tggagggtta gataaagaga ttgataaggt aggcttgtca acacttgaac gttcttttag
    17101 ggcacttatt tatgcaaatc tcttgtctgc agatgctaac cagcaatcgg ttttttatca
    17161 gggattacaa tcagaaattc gtaatgtcct tttaaatcaa ggcttgcact atctttcaaa
    17221 agaaaaggat acaacaggtt tctcaagtca gtatggttgg gttcattctt ttgcacatgg
    17281 agccgattta ctgacagagg tggtctgtca tccagacttt cctataaaca gaattcatga
    17341 agtatttgat atacttggcc aactatttaa aagaatgtcg attctcttta cagatgatga
    17401 ggattggcgt ttagcaagag tggtctatga acctatttta caagggaagt tggagcaaga
    17461 acaagtagct tcttggataa aaactgttga ttttccgata gaagaaaggg aggattttta
    17521 caaattttcc aactttagat cctgtctggt ggaagtctat gtccaacttg accagagaaa
    17581 tagtttacaa gatgacctga aagaagctat ccagtctttt caatactagg gattagctaa
    17641 tagttctatg attttcaaaa aatttccaat caattttctt gaaacccttt cctacttttg
    17701 atagactagt atctagtttt tgaaaaaagg agaaagaaaa tgaaaaaatt tgttgctgag
    17761 ttaatcggta cgttcatgct tgtgttcgtt gggacaggag ctgttgtttt tggaaatggt
    17821 cttgatggcc ttggtcacct tggaatcgcc tttgcctttg gtttggcaat cgtggtggca
    17881 gcctactcaa tcggaactgt ttcaggtgct cacttgaacc cggctgtttc gattgctatg
    17941 tttgcaaaca aacgtttgtc atcttcagaa cttgtaaact acatccttgg tcaggttgtt
    18001 ggagctttca tcgcttctgg cgcagtcttc ttcctcttgg gtaattcagg tatgtcaact
    18061 gctagtcttg gtgaaaatgc cttggcaaac ggtgtcactg tctttggtgg tttcttgttt
    18121 gaagtcatcg caactttctt gtttgtcttg attatcatga ctgtgacttc agaaagtaag
    18181 ggcaatggcg cgattgctgg tttggtaatc ggtttgtcat tgatggcgat gattcttgtc
    18241 ggactgaaga ttactggact ttcagtaaac ccagctcgta gcttggcacc agctgtcttg
    18301 gtaggcggcg cagcccttca acaagtttgg attttcatcc ttgcaccaat cgctggtgga
    18361 gttcttgcag cccttgttgc aaaaaatttc cttggaacag aagaataatt gaaactcaaa
    18421 aagccttgct cctcatcttg aggaacaggg ctttttcgta tgatactctt cgaaaatctc
    18481 ttcaaaccac gtcagcttca ccttgccgta ggtatggtta ctgacttcgt cagtttcatc
    18541 tacaacctca aaacag
//
LOCUS       DAVKBK010000031        18119 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVKBK010000031 DAVKBK010000000
VERSION     DAVKBK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.031"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..468
                     /locus_tag="VWX69_001269"
     CDS             <1..468
                     /locus_tag="VWX69_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9192614.1"
                     /translation="AIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILNKLLSYSE
                     DLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQ
                     LHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(567..2189)
                     /gene="groL"
                     /locus_tag="VWX69_001270"
     CDS             complement(567..2189)
                     /gene="groL"
                     /locus_tag="VWX69_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU9192615.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2205..2489)
                     /gene="groES"
                     /locus_tag="VWX69_001271"
     CDS             complement(2205..2489)
                     /gene="groES"
                     /locus_tag="VWX69_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU9192616.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2645..3040)
                     /locus_tag="VWX69_001272"
     CDS             complement(2645..3040)
                     /locus_tag="VWX69_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU9192617.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3118..3879)
                     /locus_tag="VWX69_001273"
     CDS             complement(3118..3879)
                     /locus_tag="VWX69_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU9192618.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3921..4547)
                     /locus_tag="VWX69_001274"
     CDS             complement(3921..4547)
                     /locus_tag="VWX69_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU9192619.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4563..4880)
                     /locus_tag="VWX69_001275"
     CDS             complement(4563..4880)
                     /locus_tag="VWX69_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU9192620.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4877..5176)
                     /locus_tag="VWX69_001276"
     CDS             complement(4877..5176)
                     /locus_tag="VWX69_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU9192621.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5461..5652)
                     /locus_tag="VWX69_001277"
     CDS             complement(5461..5652)
                     /locus_tag="VWX69_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU9192622.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5813..6487)
                     /locus_tag="VWX69_001278"
     CDS             complement(5813..6487)
                     /locus_tag="VWX69_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192623.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(6493..6939)
                     /locus_tag="VWX69_001279"
     CDS             complement(6493..6939)
                     /locus_tag="VWX69_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9192624.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPCYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7053..7556)
                     /locus_tag="VWX69_001280"
     CDS             complement(7053..7556)
                     /locus_tag="VWX69_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9192625.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7553..7915)
                     /locus_tag="VWX69_001281"
     CDS             complement(7553..7915)
                     /locus_tag="VWX69_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU9192626.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7981..9840)
                     /locus_tag="VWX69_001282"
                     /pseudo
     CDS             complement(7981..9840)
                     /locus_tag="VWX69_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9879..10328)
                     /locus_tag="VWX69_001283"
                     /pseudo
     CDS             complement(9879..10328)
                     /locus_tag="VWX69_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(10452..11168)
                     /locus_tag="VWX69_001284"
     CDS             complement(10452..11168)
                     /locus_tag="VWX69_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9192627.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12049..13464)
                     /gene="ply"
                     /locus_tag="VWX69_001285"
     CDS             complement(12049..13464)
                     /gene="ply"
                     /locus_tag="VWX69_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU9192628.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13475..13807)
                     /locus_tag="VWX69_001286"
     CDS             complement(13475..13807)
                     /locus_tag="VWX69_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192629.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTGIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13878..14486)
                     /locus_tag="VWX69_001287"
     CDS             complement(13878..14486)
                     /locus_tag="VWX69_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192630.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14499..14957)
                     /locus_tag="VWX69_001288"
     CDS             complement(14499..14957)
                     /locus_tag="VWX69_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU9192631.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15082..15481
                     /locus_tag="VWX69_001289"
                     /pseudo
     CDS             15082..15481
                     /locus_tag="VWX69_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16246..16506)
                     /locus_tag="VWX69_001290"
     CDS             complement(16246..16506)
                     /locus_tag="VWX69_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192632.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(16565..17116)
                     /locus_tag="VWX69_001291"
     CDS             complement(16565..17116)
                     /locus_tag="VWX69_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192633.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(17106..18110)
                     /locus_tag="VWX69_001292"
     CDS             complement(17106..18110)
                     /locus_tag="VWX69_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192634.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQI
                     KSVSNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKY
                     RPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS
                     "
BASE COUNT         5413 a         4063 c         3200 g         5443 t
ORIGIN      
        1 gctatcaagc gctactggaa actcattcaa caggatagcc gtaaactgag tgataagcga
       61 ttttatcgtc ctacttttcg tatgcactta accaataaag agattttaaa caagcttttg
      121 agctattcgg aagacttgaa acaccactat cagctctatc agctcttgct ttttcacttc
      181 cagaacaagg aaccagagaa atttttcgga cttattgagg acaatcttaa gcaggttcat
      241 cctctttttc agactgtctt taaaaccttc ctcaaagata aagaaaagat tgtcaacgcc
      301 cttcaactac actattctaa tgccaaactg gaagcgacca ataatctcat caaacttatc
      361 aagcgcaatg cctttggttt tcggaacttt gaaaacttca aaaaacggat ttttatcgcc
      421 ctgaatatca aaaaagaaag gacgaaattt gtcctttctc gagcttagct gacttcaacc
      481 cactacagtt gacaaagagc ctataaaaag aagggttagt cattccctcc ttttgtgttt
      541 tttataagtt gttttctata gaaagcttac atcatcccgc ccatcatact tggatccatt
      601 gctggagctg gggctactgg ttctggttta ttggctacga ctgcttctgt tgtcaaaatc
      661 aagctggcta cagatgctgc attttgtagg gctgaacgac tcactttaac tggatcaatg
      721 ataccttgat caatcatgtt aacccactcg ccagttgctg cgttaaatcc tataccaagc
      781 tcagcatttt tcaaacgatc gataacgata gatccttcaa atcctgcatt gtgagcaatt
      841 tgacgaacgg gttcttccaa agcacggaga acaatattac gtcctgttgc ttcatctcct
      901 gtcaattcca aggtagcaac agctggaatc acattggcaa gagctgttcc accgcctgca
      961 acaatacctt cttcaacagc tgcacgagta gcgttgaggg catcttcaat gcggagtttc
     1021 atttctttca actcagtttc agttgcggct ccgaccttaa taaccgctac accacctgac
     1081 aatttggcca agcgttcttg caatttttca cggtcaaatt cagaagttgt agtttcgatt
     1141 tgagacttga taaccgcaac acggtgagaa atcgcttcag gatttcctgc accttctaca
     1201 ataaccgtgc tatctttgtc cacggtcact ctcgctgctt gaccaagagc ttcaattgtc
     1261 gcatctttca actcaagacc aaggtcttct gtgataactg ttccgcctgt taagatggcg
     1321 atatcttcaa gcatggcttt gcgacggtca ccaaaaccag gtgccttgac tgctactacg
     1381 ttgaaggttc cacgaatctt gttcaaaaca agagttggaa gagcctcgcc atccacatca
     1441 tccgcaataa tcaagagtgg acgattgctt tggagaatgc tttccaaaag tggcaagatc
     1501 tcttggatat tggaaatttt cttgtctgta atcaaaatgt acggattttc aaggtcagcc
     1561 accatttttt cgctatctgt caccatgtac tgtgaaaggt aaccacggtc aaactgcatt
     1621 ccttctacga cttcaagctc tgtttccata ccacgtgact cttcgatggt gatgacaccg
     1681 tctttgccaa ctttttccat tgcttcagag atgtactcac caactttttc agaacgagaa
     1741 gatacggctg caacttgagc gatagcttct ttattggcaa cagggatggc gttgtttttc
     1801 aaagcttcaa ctgctgcggc aactgctgtt tcaatcccac gacgaatacc gattggattt
     1861 gcacctgctg tgacgttttt gattccttca cggacgatag cttgggtcaa gactgttgca
     1921 gtcgtagtcc cgtcacctgc gatatcattg gttttagaag ctacttctga taccaatttg
     1981 gcacccatat tttcaaaatg gtcttctaat tcaatttctt tggcaatagt cacaccgtca
     2041 ttggtaatca atggtgagcc aaatgatttt tcaagaacga cattgcgacc ttttggtccc
     2101 aaggttactt taacagtatc tgcaaggata tcgacaccac ggaccatagc tgaacgggca
     2161 tctgatgaaa atttaatttc ttttgacata cttactttct ccttctattc ttcaatgatt
     2221 gccaagatgt tagcttcgcc tacgatgata tacttttcat cgccatcttt gacatcaaga
     2281 cctgcgtggg cttcaactaa gacacggtct ccagttttaa cacttggagc aaccaagtca
     2341 ccgttcaagg tacgaacacc ttgtccagta gccacaactt gggctgtttt ggttttttct
     2401 tgggctgaac ctgcgagaac aaagcctcca acagtttgtt ctttttcttc tacttttaag
     2461 accaaacggt cccctaatgg tttcaacatc tgatttcctc cataatgaga tagatattat
     2521 tagcactctt tatacctgag tgctaattca tagttctatt gtatcactta gtcagaaata
     2581 atcaagaaaa aagtctgact ttctcaagat aaaaagcctg agaccaactc agacttttta
     2641 attcttaaaa tggcaattct tcctcttcca agaccaaatc tgccaaatct tggcctgcat
     2701 tattttcacg catagcacgt tgggcacgac tttccaagag ttggaatcct gtcacaagga
     2761 cttcggttac ataattcatc tgaccatttt tctcaaagcg acgggtacgc aattctccat
     2821 caacggaaat gagactacct ttggttgcgt agcttgccaa agtttctgct agtctgcccc
     2881 ataggaccat attgacaaaa tcaacttcac gttcaccgtt ttggtctttg taacgacggt
     2941 tgacagcgat agttgctcgc gctactgact tgtcattgtt ggttttgtgc aattctggtg
     3001 tagacgttaa acgtccaatc aagataactt tattatacat attttcttcc tcctacttat
     3061 ctattcgtag gaaatcaaaa aaagttacag aaatttgtaa cttttcgaga aaatttttta
     3121 ttttttatga accatgaaac ctgtcgcctg ttgattggcc ataatggtca tatctgtaat
     3181 ctgaacacga cgaggttgac tagtcacata gactactgta tctgcaatat cctgagcttg
     3241 caaagcttct attccttggt aaacggacgc agctcgttct ttatcaccat gaaaacgcac
     3301 tgtagaaaaa tctgtttcga caattccagg ctgaatggtt gtcaccttga tatccgttgc
     3361 gatggtatca attcgcagtc catccgaaaa ggtcttaacc gcagccttgg tagctgagta
     3421 aacagcggca ccagcatagg cgtagattcc tgcggttgac cccatattga taatatgacc
     3481 ttgattgact tttatcattg ctggcaagaa acagcgagta accgccatca gacctttaac
     3541 attggtatcc aacatggtca acatatccaa ctcctcatag tcttgatagg gagccaagtc
     3601 aagagccagt ccggcgttgt tgaccaagat atcaatcctc cctatcgttt ctagaatatc
     3661 agagcaaaca gtcttcacca tgaccatatc cgtcacatct agtggaaaag tccagacggt
     3721 ttgatttgga aagcttactg caaactccga cttgaggatt tctaatctgt ctatccgtcg
     3781 tcctgttaga acgacatcct caccctgctc cagataagca cgcgcaatcg cttcaccgat
     3841 tcctgaggtt gctcccgtaa tcacaacatt ttttgccatc ttatttcctt ctagctggtc
     3901 tatcagatat taacaacttc ttaggcagtc cagtgtttag ctgagtcaaa tggtgttccg
     3961 acaacttggt cttctgataa ttcaagcacc ccacgttttt gtggagcatt tggcagatgc
     4021 aattcacgag gactgcacat cataccaaaa ctcttttcac cacgaagttc acctgggaaa
     4081 atgagattcc cttttggcat catagctcca ggaagcgcga caatggtttt caaccccaca
     4141 cgcgcattgg gagctcctgc aacgatttgt acagtcttat cacttgcgac tgcaacttgg
     4201 cagatgttga ggtggtcact atctggatgg gctaccatct caacaatttc accgacaaca
     4261 aacttaggtt ccttatcatt aacaatttct tctgtaaaac cttccgcctg caactcttgg
     4321 ttcaaacgag cgacttgctc atctgtcaaa aagacttgac cgcgctctgc agtttcaaat
     4381 aaacttgaaa cttcgaaaat attccaagcc actgtttccc cattttcttt gaggaaaaca
     4441 cgggctacct tgcctttgcg ttccacattc agtttggcat ctccgctatt tttcacgatg
     4501 accataagga catcaccgac atgttctttg ttatacgtaa aaatcattgt ttcctttttc
     4561 tcctatttca atcctgctaa aaaatcgtta atttgctcct tacttttacg gtcgcgattg
     4621 acaaaacgac cgatttcctt gtccttttct agaacaacaa ggctaggaat tccgtaaaca
     4681 tcccagagtt tggccaaatc catatactga tctcggtcca ttcgaataaa ggtgaactct
     4741 ggattggtct cttcaatctc tggtaaggca ggataaatat aacgacaatc gccacaccag
     4801 tctgccacaa aaaggaagac cttcttgccc gctttttcca ctaaagatgc taattcttct
     4861 aaacttgctg gctgtatcat aagacttcct cctcatagac taggtcttca ttttcataga
     4921 caaaggtata atgacggcca tcctcaaaaa tgacgccacc aaccaagctc tccagactgc
     4981 tttcgtaaac ttgaacataa agggtcgcaa tttcccccat gtcggaaaaa tggtctcgca
     5041 caatctctgt caactcttcc tgagtcttca tgagcttacg gtcatctgca acttttttcg
     5101 tagcaagggc aaggcttccg atacctagca gagccaagcc tgccatccac atttttttag
     5161 ctttcatacc attcatttta acacaaaaaa ggcttcagga caaatgagga agcagcagaa
     5221 aagcaagtaa aaagcctctt cctttaagga aaaggacttc ttatactaag agcaaactag
     5281 aaagctagcc gcaggctgct caaaacacgg ttttgaggtt gtagataagg cgacgttgac
     5341 gtggtttgaa gagattttca aagagtatta ttcttattgc caggcaccta agttgccaac
     5401 gtagtaacca tcaggtgtgt aggtattgcg aagcatctta cctgatgaag ccagataata
     5461 ctacttgcca ttgtctttga cccaatcatt cgcaatcatg gaaccagaag aacttacata
     5521 ataccattct cccttgtcat aaacccaagt actgactttc atggttcctg agcaattaaa
     5581 ggcaaaaaaa ctgtccaata tcattcgttt tttaaaagca ttcgacacta catcatctac
     5641 gctgtagtac atagatacat caaacgtaaa agccaaaata tcgaaaaata tacaactttt
     5701 aaaggcagca tttcattttt taaagtctaa caaccataga actgaaatca gagcaaggca
     5761 tcaatttcct actctatagt acgcctattt tgatggttga agtgaagatt ttttatttaa
     5821 cgtagacaat ttccaacttc ccaaaagcca catctccacg gataatcaag gttttgctgg
     5881 ttggggctac aggagcgtca gccttagctg caccaaagga ggtttctact ttcaaatcta
     5941 cacgccagtg ttgtggaaca tagacggttg catttccgaa ggctacttca atatttaaag
     6001 ttgcaaaatc acctagcatc tctgcattat catagtagat tttagcatcc ccaaaagcga
     6061 cttccacttg gtcatctacg agatcttgat cttgcttata gaaggtcccg ctaccaaaag
     6121 cgacttcctt atccgtgacg actgtttttt tcccattgta ccaccatttt ttttcattcc
     6181 agaacttact tgaatgcgtc agataaccaa caccaagtac caccaagatg ctagcccaaa
     6241 taagagaatg attggtaact ggtaacaagt cataagcgta atttgcaatg atgagcgcca
     6301 gtaaacctgt aaaaactgcc gaagtgagat gacgtctaag gatggactca atggacttat
     6361 aagcaaaaaa aacaatacct agtaaaggcc atattttacc atccaaagaa ggaattccaa
     6421 aattcccttg cagcaagatc caagctgcta aaaccaataa aacaatacca aatgctttct
     6481 ttttcatgtt ttttacctca tgtttcttag attttctttt aggagggatt ggtaatgccg
     6541 tgagacatga acctccttgt gcgtctgata aaaggaaatg gtgcccgttc ctgaaaagga
     6601 cttgtccact gagtaaatct gacggatgtt tgcgatcgtt gacttggaaa ctcgattaaa
     6661 atagcaaggc aagatagact ccaactcata gagcttgagg cgaacctcat aagcttcctt
     6721 ctggttatga gcgtagatct tgctcccttc tgtttcaaag aagagaattt ctgacaggtc
     6781 tagataatat tcacctgtcc ccttgtaaaa agtcaacctc ggagcctttg actcttgcaa
     6841 gagccgttgc aagtctgcaa tttcatctgt caaagtgggg gtcttgatga caatttcagt
     6901 ctcctctaaa ttgccgtcaa tctcaattcg taacttcatc acatctcctt tctgactcta
     6961 ctatatcaaa gctaagttag gaatacaagg gcaaaaaagc aagtggtcaa tttgaagcag
     7021 taagtggttg taggactagc ttaacttaca tgtcagaata ggaagaaaag gaatccccac
     7081 accaaaccac aagcatagcc aaccaagaca tccttgggat aatgaacacc ccctaaaacc
     7141 ctcaccaacc ccagcaaagc tgaaaagatc aagcatacta agccaatagg tagactagca
     7201 tgcagacagg ccatggagat gatagttgcc gaaaagacat ggcgactggg catcgaccgt
     7261 cccgaactat ccttatcaag aaggggacag atatcccaag tttcataagg tctcgggtga
     7321 ttgattttct tacgaaacag ggacaaggtc acaaaacctg atgcaggaat aagcacataa
     7381 accccaactt gctgaccaag tcctagttgc aggtaagtgg tgactagcaa gatcagatag
     7441 accaggggca tggcgactgt catcaaacga ttgaaactgc gtaataggaa taaaagaatt
     7501 ggacgactag ttagtctgga gctgatattt cgataccatt cttgataatt tttcatttat
     7561 gcttctcata cttttctaga acttgttgag atgttttccc cttggcaagc caatccacta
     7621 gcttgtccaa gcgacgtatt tcctgcatca gaggatcatc aatttcctca atacggacac
     7681 cgcaaatctt ccctgtaatt gcaattcgtt cagggacata atatggtgct tgtctaaaaa
     7741 aatctccgta agtaacatcc ctatccagac aagcaagaac atcactcact tcataccctg
     7801 tcaaccaact ggtcacttgg tgaactgact ctgcctttcc accctttcgc tcaacttttg
     7861 caatcaaggc taagtagaca gcagcaaatt tcatattgta taatttctga ctcatacttc
     7921 tctctttcta tgtgtactag tataaataag aaaaagaagg ccgtcaagcc ttcttttgat
     7981 ttattcttct gcttcatctt ctgtaaattg actattgtac aagtcagcgt agaagccacc
     8041 ttgcgccatc agttcctcat agttgccttg ctcgatgata tttccatctt tcatgaccaa
     8101 gatcaagtct gcatttcgga tggttgacaa gcggtgggca atgacaaagg atgtgcgtca
     8161 ttccatcaaa cggtccatgg ctttttggat caattcctct gtccgtgtgt caacagaaga
     8221 agtcgcctca tccaaaatca aaagcggtgc atccttaaga agggcacgag caatagtcaa
     8281 tagttgtttt tgtcctacag acaaggtcac ggtgtcatcc aagatggtat catagccatc
     8341 tggcaaggtc ataataaagt ggtgaattcc cacagcctta ctagcttcca tcattcgttc
     8401 atcactaatc cctatttgat tatagatgag attgtctcga atagttcctt caaagagcca
     8461 ggtatcctgc aagaccattg aaaaggcatc atgcacttct gaacgcgtca tagccttggt
     8521 atccacacca tcaatgtgaa tacttccctt atcaatctca tagaatttca tcaaaagatt
     8581 gacaatggtt gtcttaccag tcccagtcgg cccaacaatg gcaacctttt gaccagcatg
     8641 agctgtcgca gagaagtcat agtcttgaac attgacaccg tccaccagaa tttctcctgc
     8701 tgacacgtcg tagaaacgtg gaatcagatt gaccagagtt gatttaccag aacctgttga
     8761 cccaataaag gccactgttt gaccagtttc tgctttaaag ctaacatgtt caataactgc
     8821 ctccgaattt gccgcatagc ggaaggtcac atccttaaac tcgacctgac ctttgaagtt
     8881 ttcatcagtc agctgcactt gaacagggtt ttggatagaa gaatgcaaat ctaaaacttg
     8941 attaatccgc ttagcagaga ccatagttcg gggaagaacg atgaagagtg ctcccatgag
     9001 aaggaagccc atgacaacct acatggcata agacatgaaa acaatcatgt cactaaagag
     9061 aggcagacgc gctatcgaag cagcgtcgtt aatcacatag gccccaatcc agtaaatcgc
     9121 tacactcaaa ccacttgaaa tccccatcat gataggattc aaaatagcca taagacggtt
     9181 gacaaacaaa ttcaaacggg tcaattcatc atttactgct gcaaattttt cattttgata
     9241 atcctctgca ttgtaggcac gaacgacacg aatacctgtt aaactctcac gagtgatact
     9301 gttcagttta tctgtcaacc cctgaatcaa ggactgtttt ggaaaggcta gcgtcatcaa
     9361 aacggtcgtc atcaggacgt tgacaatcac taccacaagt acggcccaga gtcagtattc
     9421 tgaatgacct aaaatcttcc caatagccca gatagccata attggaccac gcgttaccac
     9481 ttgcaagccc atagtaatca acatttgaac ttgagtaatg tcattggtag tacgcgtcaa
     9541 gaggctagga attgaaaatt tcttaatctc tgtctgcgag taatccaaaa ctcggttaaa
     9601 aatatcactt ctcagcctac tagtataaga agccgccact cgggatgcaa aaaatccaac
     9661 tgcaactacg gacaagaagg caagaaagag cattcccatc atcatgcttg ccggctgcca
     9721 caactcatct aaattagttt cttgactacc tagcaaatcc gtaattttcg agatataggt
     9781 cggcacttcc aactctagat agaccgaaaa gcaagtaaag aaaatggcta gtaaaatcat
     9841 cccccattct tttctactaa ttcttttggt taatttcttt attctctcct cctattccct
     9901 tgatattttg cctgtagttg accgagaact ttctcaaaaa tcagtaattc atcttcatca
     9961 atgtcttcca tcaactgctt gtctatgcgt tcaaaaaaag ccttaacctg ttgcatctga
    10021 gaacgtgctt tgtccgtcag acgaacaaac ttagcccgct tatcaacagg actcgcctcc
    10081 aattccacca aaccattttg cactatacgc ttaaccagat tactagcaac agacttggta
    10141 atattgagtt cctgctcgat atctttaatc aagaccaagt cttggttttt ctagcgatta
    10201 tccaaaaaac gcacaacctg accttgcggc ccacccataa attcaatgcc gcaacgtttg
    10261 gcttcctttt gcaccatcag gtgaatttga tgaccaaaac gcttaaagac taacatcggt
    10321 ttatccataa tctccccctt ctaaataaaa atagttctct ggagaataat taaatttcta
    10381 tgagaactat tttcttgatt aaaaaaatcc caagtgattt tctcacttag gatcatgttc
    10441 tataggttaa attaaaaccc atctacgttc gtataaatct tttggacgtc ttcgtcgtct
    10501 tcaagaacgc tgtaaagttt ttcaaaggtt tcaaggtctt cgcctgacaa ttccacttct
    10561 gactgaggaa tcatttccaa ttcagtcact tggaattctt caataccaga ctcacggaga
    10621 gcaacgatag ccttgtgaag gtcagttggc gctgtgtaaa ctgtgattgt accttcttgt
    10681 gcttctacgt catccacatc cacatccgct tcgagcaatt gctcaaagac tgcgtctgca
    10741 tcttcacctc caaatacaat aacacctttg ttgtcaaaga ggtaagaaac agaacctgaa
    10801 gcgcccatgt ttccgccgtt tttaccaaag gctgcacgga cattggctgc tgtacggttg
    10861 acgttagaag tcaaagtatc cacaattagc atagagccat ttggcccaaa accttcgtaa
    10921 cgtccttctg taaaggtttc gtctgtgttt cctttggctt tatcaatcgc tttatcgata
    10981 atgtgttttg gcacttgggc ttgtttagca cggtcgataa cgaatttcaa agctgagttt
    11041 gattctggat ctggatcacc ttttttagct gctacataga tttctacacc aaattttgca
    11101 tataccttag agttagctcc atctttagcc gttttcttgg ctacgatatt ggcccattta
    11161 cgtcccatta ggaatctcct tttttcacat tttaatcttt attattataa cacaagtttt
    11221 tttgattttc actagaggaa atggatttta ttagcaaatc aagctaggat agcactttac
    11281 ctgctaagat ggtcttacct ttctatcttt atcaacagac actcatccac attcaaaaaa
    11341 caaactagac cattatctgc aaatagaaag tttcagccaa gtttgacaaa gtcagctcaa
    11401 attactgttt gaagtttgta gatataagcg acaaaaacaa tcatactgca ccttttgttg
    11461 acagtctact ccagacatat catagttcaa gtaaatactt tgaaattcaa cagttcttat
    11521 aggcgctatt gtattctaag aaatcaatag aagagtttct aagcaaacct ctaatactca
    11581 ataaaaatca aagagcaaac cagaaagcta gccgcaggtt gctcaaaaca ctgttttgag
    11641 gttgcggatg gggctgacat ggtttgaaga gattttcgaa gagtataatt tacgtgttcc
    11701 caagatggag aagttagact agtacactgg cacttctaaa ccattgctag caattgattt
    11761 gttcatattt aatttcattt tttccataaa tgggtattag atataaacag caaaatattt
    11821 ccgatacgtg tcgttcttga atttccaatc atctaaaaca agtaaaggat aatcaatccc
    11881 ctgtatatca aggaattggc tacccttttt acttttttac acattctgtt tgatagattc
    11941 attttaacat cacgagcata ctccaatgga aatcgctagg caagagataa actttcagat
    12001 atccgcagag agatcatcgc ctctttttgt cgcaagcatt ctcctctcct agtcattttc
    12061 taccttatct tctacctgag gatagagagt tgttccccaa atagaaatcg tccgcttacg
    12121 cactagtggc aaatcggttt tttcataaac cgtacgccac cattcccagg caagcccggt
    12181 acactctcta attttgacag agagattacg aacattccct tttaaaggaa tactagtggt
    12241 aaagtgagcc gttaaatcct gcccatttct gtcccaagcc ttaggagtca agacttcctt
    12301 accttgatga tcataggata attcattcca agtaatataa tattgggcaa cataggcacc
    12361 actatgatcc agcagtaaat ctccgtttct gtaagctgta accttagtct caacatagtc
    12421 tgtactattt tgaaaggtcg caactacatt gtcacgtaaa aaagaagttg tataggaaat
    12481 cggcaagcct ggatgatctg ctgtaaagcg actgccttct tgaatcaagt cctctaccat
    12541 atccaccttg cctgttacaa ctcgggcacc cgaacttggg tcgcccccta aaataaccgc
    12601 cttcacttct gtattgtcca aaatctgttt ccactctgtc tgaggagcta ccttgactcc
    12661 ttttatcaaa gcttcaaaag cagcctctac ttcatcactc ttactcgtgg tttccaactt
    12721 gagatagact tggcgcccat aagcaacact cgaaatatag accaaaggac gctctgcaga
    12781 aattcctctc tgttttaaat cctctaccgt tacagtatct tgaaacacat ctcctggatt
    12841 tttaacagca tctacgctga ctgtataata aatctgctta aaattaacaa tctgaatctg
    12901 cttttcgccc gaatggacag agttaaaatc aatatcaaga gaattccctg tcttttcaaa
    12961 gtcagaacca aacttgacct tgagttgttc catgctgtga gccgtgattt tttcatactg
    13021 cattctagct gggacattat tgacctgacc ataatcttga tgccacttag ccaacaaatc
    13081 gtttaccgct ccgcgaacac ttgaattgct ggggtcttcc acttggagaa agctatcgct
    13141 acttgccaaa ccaggcaaat caatactata agtcatcgga gcacgatcga ccgcaagaag
    13201 agtgggatta ttctctaaca aggtctcatc cactacgaga agtgctccag gatagaggcg
    13261 actgtcgttg gtagctgtta cagaaatatc acttgtattt gtcgacaagc tccgcttctt
    13321 tctttcgata acaacaaact catcgggtag ctgattaccc tctttgatga aacgattttc
    13381 aatactttct ccctgatggg tcaagagttt ctttttatcg taattcatag ctagtataaa
    13441 gtcatttact gctttatttg ccatcttcta cctcctaata agttcctgga ttgagttgca
    13501 taaactcaga cttgttcagc gaaatcagcc gtggttggac taagtaatcc aaaatttcct
    13561 cgtacaattc ttctgagaca ttgcgtcgcc gtctggctag ataagaagtc ggaatgcccg
    13621 tattatccaa cataaatacc ttatctaagt caatcaaggt tggtcttgta aaaggattac
    13681 gagctagatc cggctcttct atcataaagt tcttgaccaa acgtctggtc aagagagctg
    13741 gtttgaaggt ctgattttta accaactctt tgtttttagt catgctgttg tcaatacaga
    13801 tatacatatg attcttcaca gccaaatcgc tactaatagt cggaaaaggc aaataaagag
    13861 ctacaacatc tcctctctta atcaagcaag agcaccccct tttctcctaa tgtaacatag
    13921 acaggattga ccaagtcttc tgattgactc agaatttcca aagtttgagt ttggcgcgct
    13981 gtcaatttag tagcatcttg tctcttcaat acaaaatgct tgtcgccaat aaccttgaca
    14041 atataatcct tctccaaagc tgactggtaa atccacatca gatgttgtct gtcctgagaa
    14101 ctcaagagag aaggattttc aagcctcccg atagtctgat aaaaatcaaa aacaggagct
    14161 aactcctgcc aatctgattg gctagttgtc aaggctagaa aaagggcttt gcgagctgat
    14221 acttcttggt tagccttgag agttactttc ccctccaagt tttttagaaa tcgggaaact
    14281 ccagaaagca aatttttctc taactgcgag aaataaaaac ctttcgttcc cagacataag
    14341 tctttcatgt cgctttctct agcaaataag agctcaaaca tttgatagta aaagaaaaat
    14401 atctggcact gggtcgcgct catcttttcc ttatcggctt ctttttttaa ccagagcaag
    14461 ggcgacaggt aactggattg agacatttcc tctacctcct actctttttt aactggagca
    14521 tctgcactag ctgccacttc ttttgactgg atactttccc actggttaat ctcctctgag
    14581 ataagacctt cgcatgtctt gacaaatagg gcaaaagcct tggtctttcc tgcatatttc
    14641 tccgtttggc attgatagag gaatttttct ttctccagga gttgcgcagt tttttggtaa
    14701 gaaatccaat tttcctttgc attatacaaa ttgataatcc cctcacacag caagccgaga
    14761 ctggataagg caaccgaaat caaacggtag cgatcacctg gcataggaat agcacaaaag
    14821 acagctatga ggaaacctgc cacgatttct gttattttta ataccttata gcgcctacga
    14881 tgttgaacgc ttttctttaa aaaatgagct atctgtacgt ctaatcgctc tgtcaggtac
    14941 atttcttctg gcgtcatatt cgtaactcct ttcatttact ttgataacca tagtataaca
    15001 tatttgaata tcaaagtata gtaaaaactg gactataact tattagactt cctgcgaaac
    15061 aaaatatggt atagtagttc tatgaattat gaagcaagta aacaactaac tgatgcacga
    15121 tttaagcgtc ttgttagtgt tcagcgtacc acttttaaag agatgttagc tgtattaaaa
    15181 acagcttatc aaaaaagtcg gacaagctgg taaaatcttg gctgacagtg gttatcaagg
    15241 gctcatgaag atatatcctc aagcacaaat tccacgtaaa tccagcaaac tcaagccgct
    15301 aacagttgaa gataaagcct gtaaccatgc gctatctaag gagagaagca aggttgagaa
    15361 catctttgtc aaagtaaaaa cgtttaaaat gttttcaaca acctatcgaa atcatcgtaa
    15421 acgcttcgga ttacgaatga atttgattgc tggtattatc aatcataaac taggattcta
    15481 gttttgcagg aagtctatta tatatatgca cagacatatg aaatcttttt gatacagcct
    15541 tctttttaca tagagagaca gcagttatga tatatttatc cattcacaaa atcttctgta
    15601 ccaatactac aataattggt acattttgat tacacaatcg tttcaaaaaa tatgatggaa
    15661 gactgagtat tttatagtaa ttcccttcct atcaactaga tcaaccagtt gagtgttgaa
    15721 tgttgaaaca ccctagcctc agcaaaggac tatgatcagc atttcctagc caataggacg
    15781 ctccaaatca cctattctaa gtccatcact agcttggtca gtaagataca gactgcaagg
    15841 caagactgac gtggttgatg agattttgga agagtattac aatcatagat tcaccagtag
    15901 acttgaccgc agatttaact atagtagatt gaaactagaa tagtacactt ctgcttctaa
    15961 aacattgtta gaaatcgatt tgactgtcct gatcaatttg tcctgttctc gtttcatttt
    16021 actatactaa aaaaccacct gaaacaaatc aagtgactag aggataaaaa caaagactgg
    16081 gcaaaaagtt ttgaaaagca aaaaacgcat aatatcaggt cttgaaaaac cttgctacta
    16141 tacgtttgat tgtgggaaga ttgacttcat tttctcctga aattgaagtt ttttctagtt
    16201 tccaggtata gacgaattca atatagccat ctcgctacaa ttattttaac catcgaaaaa
    16261 atttttcaga atttcaaaaa tttcattttg atccaatgaa atgtcattat tttgaagaat
    16321 agttgacttc acaggctcta attctatcac aaagcggtgc atgtctgctt ttaccgcact
    16381 acttgatgtt atagccgata acttttcatc tcctagcaag gaagctgtca aacgggtaag
    16441 gtcattcaaa tgctttttaa tggacttact taaaccttga gcacctgtgg cagagcgctc
    16501 cctcatatcc agccaagctt tagccttaaa aataattaat actcaatgaa aatcaaagag
    16561 caaactagga agctagttgc aggctgctca aaacactgtt ttgaggttgt agatggaagc
    16621 tgacgtggtt tgaagagatt ttcgaagagt atagaccaca attactcaat accgaatacc
    16681 cctgaatggt ttcttttaca tgcaccaata tattataata atcttcatcc aataataagg
    16741 ctgataaact agcatcttgg tcaaaatata agggaatttc tcgaccgtcc ttctttaatg
    16801 gatattctgg taagatacta aatagttcaa tcatagaagg aaactcagaa ttagttgttg
    16861 taaatcgaaa aagctgcgct ttctcatctt tctgacttcc ttgatactct cccaattcta
    16921 aaaaatgatt caaggtagta taaaattcct tattttttac ttcatcaatg atgaccatat
    16981 cataatcttt tgttgtgcga cttttaaatc cttgcgaatc caatacgata gaggtagcag
    17041 ttcccccaat cagaacataa tagttctgaa aatccgcaaa catttcttga aaaataactt
    17101 tcgtattagc tggcatcatc ttctcccaga tactgtaata tcatattttc tagtgcttca
    17161 ctctcttcct ctatacgtgg gtcatcatca tcttttaagg tcaaataaag agaaatcgga
    17221 tctacaaatt gtttatcatg attattttta aaatcattcc aaaactcaga tacaaaagga
    17281 cgatatttcc atatctctag catctttcct tttaaaatat gctgagaaag tggcaaggat
    17341 aactgattga attttctctg ccatatgaca tagctagtat tttcatccgt ttcagctaaa
    17401 aaagttgaat gcgacaaagc ataagcacca ccatatagaa ggttagaaac agattttatc
    17461 tgctttatat cgccatctgg caataaaatc cgttttttga tgggattaaa taaacatgac
    17521 acggatttta agaataattc tttctttgac accgtatatg tgtaaagctt attttgctta
    17581 ttttgcttgt ttaaccaata taaagcttta aaagtcctca aacacctata aattgttgag
    17641 tttggaagtc cagtgacttg tgaaagcaaa tcaacatcta ctactttttg accttttgtc
    17701 aataaaaagg caatccacgt taattgttcg ctaggtgtta attccttagg gacttcagta
    17761 tcattcgcat tgagtactag tcccaatgga gggaagaaga ggtttccctt aaagtctaca
    17821 aacggaactc tagcttgaag taattgcttt ttttcactgt ctgataactt cgaaaacacc
    17881 aaaacaacat ccatattggc tttttcaccc atagtgcgag cctgagtaac aaatgaactc
    17941 aaactccccc ttctcttttc tttaatcaat aaaaatgatt ccttatgaaa agtcatttga
    18001 gtatactcaa acctttttac aaaactgatt ggtaaagtca aagtcagttc ctcaatactg
    18061 acatcaacat aaaaggattg aaaaattgac attatctttt tgacattcat gttttttcc
//
LOCUS       DAVKBK010000032        17469 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVKBK010000032 DAVKBK010000000
VERSION     DAVKBK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.032"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(515..1651)
                     /locus_tag="VWX69_001293"
     CDS             complement(515..1651)
                     /locus_tag="VWX69_001293"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU9192635.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNDFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPTQSHEDSLFVMVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(1713..2150)
                     /locus_tag="VWX69_001294"
     CDS             complement(1713..2150)
                     /locus_tag="VWX69_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9192636.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(2152..4107)
                     /locus_tag="VWX69_001295"
     CDS             complement(2152..4107)
                     /locus_tag="VWX69_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9192637.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEIMKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(4131..5900)
                     /locus_tag="VWX69_001296"
     CDS             complement(4131..5900)
                     /locus_tag="VWX69_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU9192638.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            6109..7449
                     /locus_tag="VWX69_001297"
                     /pseudo
     CDS             6109..7449
                     /locus_tag="VWX69_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(7577..8599)
                     /gene="cbpF"
                     /locus_tag="VWX69_001298"
     CDS             complement(7577..8599)
                     /gene="cbpF"
                     /locus_tag="VWX69_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEU9192639.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRQEIAFRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWV
                     YDDGDWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQHLGNKWYYLRSSGAMATGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(8618..9439)
                     /gene="cbpG"
                     /locus_tag="VWX69_001299"
     CDS             complement(8618..9439)
                     /gene="cbpG"
                     /locus_tag="VWX69_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU9192640.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHSYYRHDYGKEADDIYVLPAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYHLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(9520..9759)
                     /locus_tag="VWX69_001300"
     CDS             complement(9520..9759)
                     /locus_tag="VWX69_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192641.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(9909..10175)
                     /locus_tag="VWX69_001301"
                     /pseudo
     CDS             complement(9909..10175)
                     /locus_tag="VWX69_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(10200..10511)
                     /locus_tag="VWX69_001302"
     CDS             complement(10200..10511)
                     /locus_tag="VWX69_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9192642.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYKHPELEEIILIFFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(10436..10667)
                     /locus_tag="VWX69_001303"
                     /pseudo
     CDS             complement(10436..10667)
                     /locus_tag="VWX69_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(10668..11300)
                     /locus_tag="VWX69_001304"
     CDS             complement(10668..11300)
                     /locus_tag="VWX69_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9192643.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(11314..12309)
                     /locus_tag="VWX69_001305"
     CDS             complement(11314..12309)
                     /locus_tag="VWX69_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9192644.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(12306..13004)
                     /locus_tag="VWX69_001306"
     CDS             complement(12306..13004)
                     /locus_tag="VWX69_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU9192645.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(13081..14091)
                     /locus_tag="VWX69_001307"
     CDS             complement(13081..14091)
                     /locus_tag="VWX69_001307"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU9192646.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(14075..15082)
                     /locus_tag="VWX69_001308"
     CDS             complement(14075..15082)
                     /locus_tag="VWX69_001308"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU9192647.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDILIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSFEEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(15069..16022)
                     /gene="mvaD"
                     /locus_tag="VWX69_001309"
     CDS             complement(15069..16022)
                     /gene="mvaD"
                     /locus_tag="VWX69_001309"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU9192648.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEYLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(16004..16882)
                     /gene="mvk"
                     /locus_tag="VWX69_001310"
     CDS             complement(16004..16882)
                     /gene="mvk"
                     /locus_tag="VWX69_001310"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU9192649.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITETCVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(17004..17183)
                     /locus_tag="VWX69_001311"
     CDS             complement(17004..17183)
                     /locus_tag="VWX69_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU9192650.1"
                     /translation="MLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNT
                     TVDGYFVNYNGEWVQ"
BASE COUNT         5376 a         3831 c         3056 g         5206 t
ORIGIN      
        1 tgtttcattt tactatatag atcacattcg aaagaattcg ttccaaaatt gcttggttcg
       61 ttcttctctt ggacgactaa agaattgatg ggcattattt ttttcaacaa ttttcccact
      121 gtccataaaa ataacatgat gggctacatc tctagcaaaa cctatctcat aaagctgatc
      181 aaaaactcaa tctgaggaga aaatccaata agactttcca taataaagga catcctatca
      241 agatttttga acacccgata ggctgccttt ttccgatttt gaagactttt tgtccagctt
      301 cttttacctt ataaataaca acaaaaatca aagacaagct agaaagatta ccgcagataa
      361 ctcaaacagt gttttgaggt tgcagataag actgacggag tcagctcaaa gcactgcttt
      421 gaggttgtag atagaactga cgaagtcagc tcaaaatact gttttgaggt tgcagatgga
      481 tgctaacctg atttgaagag attttcgaaa aagattaaat atactctaca atttgctcaa
      541 tcaattcttg gtcgtctaaa cctgtaactt gtataacaac atctttgact gattgtttag
      601 ccaacaattc acctaatcga atactttctt catcatttac atcgcgatag tcaaaggcat
      661 agccaactgt tttaagtagg tttttatatg acaaactgag ttctttcaat tcacgtatcg
      721 gccggatgaa tcgttcatta tagcctaatt ttcggattgg agtacgagct acgcgactaa
      781 cctcgtccac tatgaaaggg ttttcgaatc gttctataat gactttgtga taattctcca
      841 attctttttt atcaaagttc catttggcaa tcaagagact ccgaatttca gctaatacag
      901 attcaatccg agatttgata ttaggatttt gaagagcttc caaaattgtc ttggcaccat
      961 aatgcgcacc aatgtaagct gaagttgcat gtccagaatt gactgaaaaa agttttcgct
     1021 caataaaggg ttctaaatct tcttcataat gcacatcttc tagacgtaaa tctggatttt
     1081 taagacgctt ggtttccacg acccattcat taaagggctc gaccataaca aaaagggaat
     1141 cttcgtgact ttgtgttgga acaatcctgt ctactgcagc atttggaaaa cctatgtagt
     1201 tatcagcaaa tgtcaaacct tccggactta aatatttctt gacttcttga taaagaaatt
     1261 gagacccgcc aatcatattt tcacaggcca taacatccaa tgcctgtgta tttcctgcaa
     1321 ctcggcgagc ttcgattcct ttggctagaa gttcagcgat aaaagggagt atattaggtc
     1381 cgattgcagt agtaataata tccgtctttt gaatcgcttc aatgacttgc tcaggatgtt
     1441 ctttgctatt aattccagcc acattagtta cttctatacg agactgtcct ttctgtgcaa
     1501 tttcaatttc atacttgccc ttttcattta gagcatgaat tatctgatta ttgacatcca
     1561 caaaatcaat atggaaatca tttttaaata gaatttcacc tataaaacca cgaccgatat
     1621 taccggcacc aaaatgaaca gaatgtttca ttcaatttct ccttttccta tttgagggac
     1681 atatatacta gatgacaaat gacgaaattc aattattcaa cagcatcaaa taagcgcaat
     1741 acttcctctt ttgactgagc atctgctagt ttaagaacat tatctacatc tgcacagaag
     1801 atagaaattt tctgaataat ttctaagtgt tcattaccaa taccagcaat accaaaaaga
     1861 accgttgcca cttgagggtt agatacattc ccaaaatcaa cccctctagg gacttgaacg
     1921 actgtaatac cagacttgag gacatcattt tttgctgcat ctgttccatg cggtatggcg
     1981 ataaagttac ccatgtaaac agatagctct ttatctcgct caatcatggc ttcaatatag
     2041 tcttcattaa catatccacc ctcataaaga acttgcccac aataacaaat agcttcctcc
     2101 ttgttagaaa attgtttatt aagcttaatc aaatgttttt caagtttcat attagttctc
     2161 caatttctta attttttcgt taaaaatagt atttagcatc tgataaataa tggattgatt
     2221 tcccgtcttg taaatctctg tataaagatg attttcaata atcgactgac tgatagctgt
     2281 cattaaatct ctcgcttcct cgctagcttc tttagacatt agcattagca gacacctttt
     2341 gacctcttct tcctctcgtt tcattgacaa tgcggagata ggtagtttga gttcaaacat
     2401 agtaaaacta tttgttgtta ctttgctaga ctgactatgt aaaagcacca gaccagtatt
     2461 aggaatagcc ataggactat tctggaagtg agataacaat tttcttgtta ggtaatctct
     2521 gtcactcaca ttcttctgat attggatgat ttgttctacc gtgtgctcaa atgattgatt
     2581 attctccaat tgaaccaact cgaattgact caaaagctga ctactagata ttaaataatc
     2641 ttgcaagtca taacttttct ctggagcgat agcatcacgc gcgacaattg tacgatgtgc
     2701 ctgtacatac tgaagtcgtt cctgtaattc aagcaattct ttgacggttg gaaaactaga
     2761 aattacatcg atttcctgat tagtcagcgg cttggtagat aaaatataat catactgact
     2821 gagatcaata ctgtggtaat ctactagaga ctgaatatct atcaactcta caaaaggagc
     2881 aacactctta attttactga ctaataaatc tctagtgacc cgacgttcat ccgttaaaag
     2941 caaaacacgg actggataaa tctctggact acggcctaag ctagagataa aatgtagggc
     3001 aatcatgcca tactcatact ctgtatgaag atatttcgga aaaatatcat tcactaaaag
     3061 actgatgact gtataaagaa atttattcct ttcaactaaa atctggacag attctggcaa
     3121 attttcaccc tgaaaaagga tagggacgcc taaactgagc cgaatatgat ggaaaagaaa
     3181 attgaataaa accttgtcct taaaaaagtc aatcttggta tacatggaaa ccgtatcaat
     3241 cagatttgaa atattgtaga aaaattcacc atcaaatttc tccgtaaaga gcggattgtc
     3301 ctgacgttta atgattaatt catccaagat gctcgcaaaa tagataattt cctgaatact
     3361 ataaaattgt gcagtctgct tagagtaagt ttgaaaaatt ttttgagaaa tttccaaagc
     3421 ctgcttacta gtattaggtg aattttcaat gttttgctcc tgacctataa gagataacaa
     3481 gatcgcaaaa aacatcttca tcctagcatc catatctgga aaacctgaca gttgcttatt
     3541 aacaatctga ctggccagcc tagttctatc tgcttctaaa atatcaaagc tcccaaaatt
     3601 accggttgaa aaatctgcta ctgagataca gtttgtcagt aaaatagcca aaaatcttct
     3661 cttaccaact gaatcaccag aaatccgata acctttttgt cgttcaattt tcagatcaaa
     3721 gtctaaaaga cgcttatcaa tatctgaaat atcctgaata atagttacat tactgacttt
     3781 cgtgcactct tgcaatgctt cattggtgac aaaaccgctc tcagtcagaa ggcgataggt
     3841 aatcaactct tgtctttctt ggggactata ctcaactaac acttcaagtt ctgtcggcaa
     3901 atcatccaac tctccagtca aaatatagta tttcccatgc ttcattattt cgattccata
     3961 ttgctccatg ctatctgtca aatctgataa agttcgataa attgttctag atgaaacctg
     4021 taagatttca gtcatatctt gcattgaaag cttccctaca tgtaggaaag ccttcaataa
     4081 ttgttcttct cgtttggtta atagcattcg taatttagaa acctctagtt ctatttgtac
     4141 attctagcag ccattttgtc atattctggt gttgttacta aactatccac aataagaaat
     4201 tgagaattcg gtgctgcttg ctgcacttct gcctgtaaag aaatagttgt tacaatcatt
     4261 atgtttttag aattaaattc acctaattct gaaattttgg cagtagaaac tggaatacga
     4321 atattcttgt ttctaaagat agcccgaatc gtttcacagc ccatagttgc agttccctgt
     4381 gctttaccat aagcaactac tacagcatca atatggttaa ggtcaatttc ctgactatct
     4441 actggtgctg aagttggtat atctccttca atttctgcta ttggagaagc tcctgttaat
     4501 gaagctacaa tttcatcata acgaggggac gctaagaaat tatcaacaga aacatgaata
     4561 gcacttggac tcttgtcttt agctcttggt gtcagttctt cctgagtaac aattaatgtt
     4621 tttggtgtat caagcaaatt tgagattgcc tgattagata ctggaatctc tagacctgct
     4681 tttttaacct tatctcgaag aatactagct cccatagcag agcttcccat accagcatcg
     4741 caggcgaaaa tgattttttc cactgagtct gtcgaaacaa ctgcatcaac agaagttgat
     4801 actaactgac ctttagactg agccttagct gcttgggtag ccgcctgagc agcttcgagc
     4861 gaatcctcag ttgacttgtc tgcatgaaga ataagggctg ctacaaggaa agaaacaact
     4921 gctgctacta aaacacctag aagaacattt agatggggcc aaacaccttt tggcgccgta
     4981 gccataatcg caataataga acctggtgaa gctggagatt taagaccagc gtctaagagt
     5041 tgaaaagtaa aagttccaga gatacctcct gccatagcag ctaaaaatag agtaggcttc
     5101 atcataacat aaggaaagta aatttcatga atccctccga agaaatgaat aaccattgcc
     5161 ccccaagaag aagatttagc agaaccttta ccgaatacag cataagctaa tagaattccc
     5221 aggcctggtc caggattagc ttccaatagg aagagaattg acttaccagc ttgagctacc
     5281 tgttctactc ccagaggagt aaaaatgcca tgattgaggg cattattgag gaaaaggact
     5341 ttagccggtt cgatgataat attagccata ggaaggaggc gagcattgac aatagcctca
     5401 acaccattcc caacagctcc agtaagagtc gatacgactg gaccgattgc gtagaaagcc
     5461 aaaagcaata atgcaaaacc aacgagacca gctgagaagt tattaactaa catttcaaat
     5521 ccgggacgaa ttttttcttg gaacttctca tcaaatttct tgatagtcca tcctcccagt
     5581 gggcccatta ccatagctcc gataaacata ggaacactag aacctgtgat tgcaccaaca
     5641 gtagcaatag ctcctacaac ggcaccacgt tggccatgga tcatatatcc acctgtgtaa
     5701 ccaatcagga ttggcaataa atacgttaac ataggaccaa caacagtagc taactgttca
     5761 tttggcagat agccatcagc gataaagagg gcagtcaata ctccccaagc aataaatgct
     5821 ccaatattgg gcataaccat atttgaaagc gatgtcccta gtttttgaac cctgactttc
     5881 aatgatactt tttcttccat tagatcatcc tccttttctt aaaactagta tatacaaagt
     5941 taaaaacctt taaaactaaa gttttgtcac agattttgtg tcaaaacatt acttttgacg
     6001 aggctgggca aaaaggctta aaaattataa aacgcatcat atcaggtgta catgaactac
     6061 accccaaaag ttagacagaa aaaatctaac ttttggggtg tttttattat gaaactaact
     6121 tatgatgata aagttcagat ctatgaactt agaaaacaag gatatagctt agagaagctt
     6181 tcaaataaat ttgggataag caattctaat attaggtaca tgattaaatt gattgatcgt
     6241 tacggaatag agttcgtcaa aaaaggaaaa aatcgttact attctcctga tttaaaacaa
     6301 gaaatgagta ataaagtctg acatgaaggc tggactaaag atagagtttc tcttgaatac
     6361 ggtctcccaa gtcgtacgat acttcttaac tggctagcac aatacaggaa aaacgggtat
     6421 actattgttg agaaaacaag agggagagta cctaaaatgg gacgtaagcc aaaaacgaga
     6481 cctgaagaga ggacagaatt agaacgtctt caagcagaaa atgagtacct gagagcggag
     6541 aatgccatcc taaaaaagtt aagagaactc cgattgaagg aggagaaaga agaaagacag
     6601 aaattgttca agaattaatg actgaatttt cgttagctct tcttctaaaa gtcattaaac
     6661 tagctcgttc gacctactac tatcacttga aacagctaga taaaccagat aaggactaag
     6721 agcttaaagc tgaaattcaa tccattttta tcgaacacaa gggaaattat acttatcgcc
     6781 gggttcattt agaactaaga aatcgtggtt atctggtaaa tcataaaaga attcaaggct
     6841 tgatgaaagt actcaattta caagctaaaa cgcgacagaa acgaaaatat tcttctcata
     6901 aaagacgttg gcaagaaggc agagaatctc attcaacgcc aatttgaagg ctctaaaaca
     6961 atggaaaagt gctacacaga tgtgacagaa tttgccattc cagcaagtac tcaaaagctt
     7021 tacttatcac cagttttaga tggctttaat agcgaaatta tcgcctataa tctttcaact
     7081 tcacccaact tagaacaagt acaaacaatg ttggaacagg cattcacaga gaagcactac
     7141 aagaatacga ttctccatag tgaccaaggc tggcaatacc aacacgattc ttatcatcgg
     7201 ttcctagaga gtaagggaat tcaagcatcc atgtcacgta agggaaacag cccagacaat
     7261 agtatgatgg agtccttctt tgggattctg aaatcggaaa tgttttacgg ttatgagaag
     7321 tcgtttcagt cgcttaagca attggaacaa gccattatag actatattga ttactacaac
     7381 aataaacgaa ttaaggtaaa actaaaagga cttagccctg tgcaatacag aactaaatcc
     7441 ttcggataaa ttaattgtct aactgtttga gggcagtaca gaaaaacctt gatactatgc
     7501 gttttttgat tgtgaagact tttatccacc tattatacaa agttaagtat ccatcacagt
     7561 ttacaattag ccttcattac ttaacccatt caccattata gtttaagtag taaccaccta
     7621 ctgtggtatt aacagctaaa gcacctgaat cataggcata gtaccagtta ccattgactt
     7681 ggaaccagcc tgttttcata tctccattac ttgcatttag atagtaccaa gtcgaacctt
     7741 cctgatacca accagttgcc atagctcctg atgaacggag atagtaccat ttgttcccaa
     7801 ggttttgcca accagttttc atatcgccat tttcagcatc taaatagtac caagttgaac
     7861 catcttgata ccagccagtt gccatagctc ctgatgaacg gagatagtac catttattac
     7921 caagatgttg ccaacctgtt tgcatgatgc cagttgctgg atctagatag taccatggag
     7981 ctgcttttag cttctcttca tcataggtaa gagggtaatc cttaacccaa ccacgtgcta
     8041 gctctccaac cgtcaatctg ttgatgcgag aatcaaagcc accatccttc tgcaaataat
     8101 accagtcccc atcatcataa acccaaccag tttttaaagt atgataacta cgctgatctt
     8161 caaaataata gactcgtttc tctgctgggc tatcatattc ttccccatga tgtttgttgg
     8221 tatttgtagc agtttttgct tctaacactt gcttgccaac aaattcttgt agtaccccat
     8281 cttgaccaaa gtaaaaccaa tctggtctaa aagcaatctc ttgtcttgga gaaggaccaa
     8341 tcgtaacccc cttgtgtgga gcaggtatat attgccagcc gacaaccatc tctccggata
     8401 aaggatcaaa ataatagtat ttcccatcta tcactctcca gtaggtttct tttagatccc
     8461 cctttttgta gtaggttcta ccattttctt ggacaaactg ccatccttca gaatcatctg
     8521 caaatactgt actggtccct agcaaaccga agaaaaatgt ggctagtgcg acttgcatca
     8581 tttttttcaa aagcttcatt ttatatatcc tccaacatta aatccactca ccagatgaag
     8641 cgaagttata aactttacca tcgatagttt ggctacctgt aaccattgct ccatttgaat
     8701 tgagataata ccattttcca tttacttttt gccaatctgt aagcatctta ccggaactgt
     8761 ctaaatgata ccaagtatca tttatctcct gccaacccgt ttgtttatca tgttgtctat
     8821 aatggtacca actaccattt attttcttcc atccttcaag agagtaacct ttaagaaccg
     8881 aataaataaa tggcaaattt cgttcattta atttaactgc actgttaatt tgattagctc
     8941 catctcctaa agtatgcact cctactacac ggtgactagc atcataaact gtagatccac
     9001 tagacccctc taaagtatca acttggtaat ccaagaacat gccatcatca cttaaaactt
     9061 gttttttatc tgtatacatt tgatgaactt taaaattata tgatggatag cctgtgatag
     9121 tcacagttat tcctgtcaaa tttttttgac tagtaggaag acccaaagtc cctaattttg
     9181 caccaatggg ctcttctaga attaataaag ccaagtcata ttcccttgca tccttagaat
     9241 ttaaatttct aaattccttc aaataacgaa cttcctttac tttgatcttt ccaaatggtt
     9301 cttgacttgg actaacagcc ggaagaacat aaatatcatc cgcttctttc ccatagtcat
     9361 gtctgtagta gctgtgagcc gctgtaatta acacattatc tttaataaaa ttcgcacttc
     9421 ccctcccttc tacattcatt ccatcggcta ctccataata cttagataaa accatagctg
     9481 aagtcgaata cggatactgt aaagtattat caattttaat caaatcatca ttaccgataa
     9541 tacttctgat tgcttttggt agtatgaacc atatgttggt gaaatctcag ataatgaaga
     9601 atcattagat cctggacctt tttctagtgt ctcacttacc tcatattctt cacccgtact
     9661 agaaataaca ctcaaagcag atactgtcga taactggcta gccaataaag tactcgcaat
     9721 aattgaaata cccaattttt tataaacagt tttcttcatt attgtatcct cctaatgtaa
     9781 ttatagcgta ctattctaaa tttcttaatc tactatagaa tcaagaaatc taccaccttc
     9841 tttaaatacc ctccattatc acataaacag gtaaactttt caattaatga ctgcgctttt
     9901 caatcacgct agaggtactt acttgcttct ttgatactaa gttcagccat tctttccttg
     9961 tttttctcaa taaagcatgt tacccaagtg ggattcgttt tggagtagtc tcgcagagtc
    10021 cagccaatgg ctttattgat aaaaaattct gtttggttca agttatgaag gagaatcttt
    10081 tccattaatt gagtattggt cttctctttt cttaacaact ggttgtcaat agcgacacgt
    10141 ctcagccaga tattatctga taggctccat tttatactca atgaaaatca aagagcaaac
    10201 taggaagcta gccgcagatt gctcaaaaca ctgttttgag gttgcagata gagctgacgt
    10261 ggtttgaaga gattttcgaa gaatattaag attatttctt ctagttcagg atgtttatac
    10321 accaaactcc ctactactcg atctaggata tctaccgtgt cccaccagga ttttgtcacg
    10381 actaactgct ctagcttagg caaatcggtt tcctttagat aagactgcat tgctttcaaa
    10441 tagttagcag ccacatattg gtattttcta ggctcctttt cccagcaagt gtctgcaaaa
    10501 tcccaatcga taatctttgt ttttttcgct tctggaaaat atttttatag agtttatttc
    10561 tttcaaccta gaaaagaaaa ttgatggcac atataggctt ccatgggcct tgctttttta
    10621 gagtcttttg ctgcttctag ctcctcaagt aaatctgcta aactcatcta aaactcctca
    10681 tgccccacca aatggtgctg aaaggcatag acagccgcct gggtacgatc gctaacttca
    10741 agtttggcaa gaatgttgga cacgtgggtc ttgaccgtct tgagagagat aaagaggtca
    10801 tctgcgatgc gctgattttc gtagcccttg gcgatgagtt ggagaacatc tcgctcacgc
    10861 gcagtcaatt cttcatgaag ttccatatga ttgcggtggt attcaacctt cttgctaacc
    10921 tcttgctcaa tggccagctc gccagcagct accttactga cggcatgaag caattcatct
    10981 gcactagaag tcttgagcat atagcctttg gcaccagcat ctaagactgg catgattttt
    11041 tcattgtcca aataagaggt cacaatcaaa atcttggctt caggccattc tttaaggatt
    11101 gctaaggtcg cgtcaatccc attcatctca ggcatgacaa tatccatgac aatgacatct
    11161 ggacgcagtt ccaaggccaa gtcaatccct tgagacccgt tggacgcctc acccacaact
    11221 tctacatcgt cttggaggtc aaagtagctt ttcaagccca atcggaccat ttcatggtca
    11281 tctactagta aaattttcat ctttactcct ttatcattcc ttatctaaca ggggaatacg
    11341 gatatcaacc gccagccctt gcttgggagc tgtcaagagt tgaactgttc cagccatatc
    11401 ttcaacccgc tccttgatat ttcgcagtcc ataactcaag tcgtctaagc tccctaactg
    11461 gaaaccaatc ccattgtcca ccaccttcag ttgcaattca acatctgtct gatagaggta
    11521 gacatctagg caagatgcct gggcatggcg gagggtattg ctaatcaact cttgcaggat
    11581 acggaagata tgctcctcga ttttcttagg caatttcgtc atattctgct tgagactaac
    11641 cctaagatca ctcttgtcct caagctcttt taagagaatc tgaatccctt ctatcaagct
    11701 cttctgctcc agttcaactg gtcgcaaatg caagagcaaa acccgcaaat ccttctgggc
    11761 tgtttctaaa atagctgtga cactctgcaa ctggatctgc atcttttctc tatccaattt
    11821 caaagcctgc tgactgatac ccgataaaat catgtgggcc gcaaacaact cctgactgac
    11881 tgtatcgtgc aaatcccgag caattcgctt ccgttccttc tcgatgattt cctcttcctg
    11941 agcaaggctc tgattttcag ctttttgaag agcttctgtc aaaaggttaa gtttacctga
    12001 taaggacttg aaactggcat ccaaatctgg atctgcaacc tgaaccactt cttgccctgc
    12061 caataaacgc ttgagattag cctgcatttt tcttagagaa agctcttcga tccctcgcca
    12121 aaacagggct aagagacagg ttatggacat gctgaaaacc aacaataaaa agacaaattt
    12181 ttctgttttt tcgacatcgt gcaaaaagat agaccagtca aaatcaagta tttccagcaa
    12241 gctgtgggag aaaaaaaaga caaacaggaa ggaggtgaga gcaataatga cataggcttg
    12301 ttttttcatc ctctaaccac ctccacatca ccaatcatag tggtcaagaa aatcttgaca
    12361 ctcttgttac tcttgagata gtcttttgtt tcttgatgat agtgttcatt gcggagggct
    12421 cgcttgggct ggttgaaaaa agtcaaatcc ccatagagac agttaacgct gagactgact
    12481 tccacatcta caggtacgat gattttggtc gttcctacca tctttctgag gataatgaca
    12541 ttgtcatgat tggttaagat gaccctctcc agatgaatag tgtccttgcc catgaagcga
    12601 aagagattga tatcatcgaa ttggcaagtc tggtagcttg aaaaatgatg aagatttcca
    12661 aaccaacgat ttttctcctt cttaaccgtc acgacctctt caaaaaccaa attggtctgc
    12721 tctttttcct ggttcatcat cgggtaaaga agaaagaggc tatagataac cgcaacaaaa
    12781 atagctagaa tcacaaaagg attgagcata acgatgaaaa agaagagaat ggttgccgct
    12841 actaaaagaa gattatttcc ctctttacca gtgtagtagc gaatcaaaag caaaaagagg
    12901 aatagtatca gcagaaaacg cgaaaaatgc tctgatacca tcaaaatcag agctcctgtc
    12961 agaagacagg cttcgataaa taaaaagatt ttaaattttc tcataggttc atcctctccc
    13021 ttctatttta tcacaattca aaaaagtcac ctcagtctga ggatggaaaa aaggcgctgg
    13081 ttacgccttt ttcatctgat cctttgcttc ttttaatttt ccataaagaa gatagtctac
    13141 tttttgtaga tctgctatgg tggcacagtt aagggaacac ataatcaagc gtaggtctgc
    13201 tttccagcct tggacaatgc caatcacttc ttcaactgtg taggtttcaa ccaattccag
    13261 aacggttcgt gacaatccca cagacttagc accaaaaacc aagcacttaa tcatatccag
    13321 cggattccga acccctccac taaccaagag ttcgacctta tctttccatt cttgggcatt
    13381 gagaagggcc tgcatggtag actgacccca ttgattgagg taatcacgct ggccactacg
    13441 acggttttcg atataggcaa agctggtgcc accacgaccc gataggtcca ctgtacgaac
    13501 accgaattca taggctcttt cgattgtctt ggcatccatt ccaaagccca cttccttgag
    13561 gacaatagga acgggaattt gctcgctata atctgctaga tgcgattgcc agcttctaaa
    13621 cttcctttct ccctcgggca tgagtaattc ctgcatgaca ttgacatgca cttgcaatag
    13681 aacaggattc atctcttcta cagtctgaag tcctaactcg acaggcttgt ccaatccaat
    13741 attggttcca aggaggagat tgggatgact agacttgaca gaaaaagaat catccgttgg
    13801 atttttgagg gctgcgctat aagaacccgt tacaaataaa ataccacagg attccgccac
    13861 ctgagccagc ttttgattga tttctcttcc cttattactt ccaccagtca tggcattgat
    13921 ataaaaagga aagtcccact ttcgaccagc aaactctgtc gaaagatcga tttcatccag
    13981 attgtaaaga ggcaaggaag aatgaatcag ctccacctca tcaaagctat tataggaact
    14041 tttctgctca agggcataga ggatatgctc gtccttacga tttgtcgtca tgtcctatcc
    14101 tttcttgata taagagctca atccccagat cggcccaacg attttttaag gttttggttg
    14161 attgcgcatc aaaactcagg gcgatgccac agtcaccacc accagcacca ctactcttgg
    14221 caacggcctg caaatcttga ctggcttctt tcaactgtct aagcaaaggc gtgtaaatat
    14281 ctgtactcaa gccttctaaa agcttgctgg ctacttctac ttgctcgata atcttttctg
    14341 atttcccctg ttccaaggct tcctcaaaag aaaccaccgt ttcttttgag gaagttaaaa
    14401 aattttgatt gatattttgc ttgatttgct ggaccatgtg actcgataca gccacttcct
    14461 tggtccatcc cactaagaaa tcacattcta aagttggttt cacttgtgaa attgaaaagc
    14521 cccaatcacg ctccagaact gtcgccaagt tttcttcttc taaccaagca gccaccttct
    14581 ggcgatcaaa tgactggtag agaaccaaat cctctgccac aatacaggca aggtcgccca
    14641 tggaaccatt gtctcctcgc ttgagcaaga cagcgctagt cagcttgaac aagagctcct
    14701 gatcaacaga aacatcatac agagccagta aagccttgac aaccaagaca acgacgctgc
    14761 cactagaacc tagaccaaac tttttccctt ctcgttccat tttgccacag atttctagag
    14821 aaaaaggtct taaattctga ccacgaacag cgaggaagtc tcccatcaaa gcaatcgttt
    14881 cttgaatcaa gctgtagtca ggattaggcc ttaagtccac tgcgaaatca aacatatctg
    14941 aatagatacg gtagctgtca gaaaaagcaa tctcagccct catatagatg agaatatcct
    15001 ttatcaaagc taactgccct ggctctaaaa tagcatattc acctgcccaa tagagttttc
    15061 cgcaagtttt aacagcaatc atcttgactc aaatcctttg tttttgacac aatcaagcga
    15121 taacgctgac cgaaaatttc tgacaaatac tccaagtctt tctcctgaca gaagacctta
    15181 acattgggac cagcatccat ggtaaagtag caggcctctc ctttctcacg aagctggcga
    15241 acaaagtcca tagcctcata agaggcatcc gtcagataag aaaaggctgg actagcagtc
    15301 tttgtcgtag catgcatagc cagggcattt ttctccgtta attctccaat cttggcaaaa
    15361 tcattttcct tgagataaat cagcatatcc tgatagtcct tctcagactg acgaacccag
    15421 tcgtcgaaag tcgtcgaggt ttccacacaa agtttcatcc cgtcacggct agagattggt
    15481 tttttcttgt cctctagcac caacataatc atagctagtt tcaagtctgt ctctacaggg
    15541 taaatttctc cactatcctt atcccaggct cctagtggtc cataaaaact ccgagaagaa
    15601 gagcctgagg caaatttggc ttcctgtgcc aactgacttc tatccaatcc aagcttgaaa
    15661 taagcattac aagccttgac cagggcggac aaaccactag aacttgagga caggcccgct
    15721 gccgtaggca tattgttttg agtatcgata cggacaaagc cctcaccagc tggacgataa
    15781 cggtcaataa tcttactcat cttggcatgc tcgacctcat tttgtagctg accattgatg
    15841 taaaattcgt cagctgttac attggctggt aaaggcgaca aggtcgtctc tgtatacata
    15901 ttttccaaag ttagagaaat actgctagta gcaggcacca tctctttttc ttttttcttt
    15961 ccccaatatt tgataatagc aatatttgcg taggaacgta ctgttacagg ctctctatcc
    16021 atgtctgaac agctcctttc tcttctaatc tttctgctag ttcttgtgcg tgtgtcaaat
    16081 tggttaccaa ggctatgata caacctccta gcccaccacc gctcatcttg gcacccagag
    16141 caccatggct aagagtcgtt tcaaccaaaa agtctgcctc agggctactg actccaattt
    16201 cttttaaatg taaatgcgct tgactgagga tttgtcccag tccttcagca tctttttgtg
    16261 aaatcgcaac ttctgcttgc tgggttaatt ctcccaaggc atgcaaaaac ggtagggcat
    16321 ccttgccctt attttgaacc acttggatgg cttcacgagt atgaccataa acacccgtat
    16381 cggcaatcac caaataggcg gataaatcca tctcaagttc tgtaaatcct acgttcttga
    16441 taaagcgaat aggttggtca ctgagacagg tcttagcatc caaaccacta ggattcatat
    16501 gagcaatcat ctcagctcga ttgaccaaga tttctagtac atcatgaggc agatcagcct
    16561 gatagtagtc aaataccgca cgaatggccg ctatgctgat agccgctgac gaacccatcc
    16621 cccgtttctc agggatagcc gagtcaatct cacaacgaac gcaggtttct gtgatatcca
    16681 aatactccag tgaagcataa accgccatgg acaaggtatc ctcctcataa aggcgccaag
    16741 gactctctgc aggaactacc ttacaggtca cctccacctc caaaagaggc agggaaatgg
    16801 caggataacc gtaaacgacc gcatgttccc ctattaaaat tatcttacta tgtgcctgac
    16861 cgacaccaac tttttttgtc attttttcct tttactagac gaaaaaacgt cttatttttc
    16921 atacaagtat taattctttc ctatctattt tattatattt tcacaaaaaa agcgattgtt
    16981 tccattcaca atcgcttctt tcattattga acccattcgc cattataatt gacaaaatag
    17041 ccatctacgg tcgtattcac tgccaaggca cctgagctat aagcgtagta ccatctgcca
    17101 ttgacctgga accaacctgt cgtcatagaa cgacgaaaga aactccatac cattaagtaa
    17161 agaggaaagt cgtgagggag catgcgccat tgacaacctg ttttagtgac gtacaaagtc
    17221 tcattaacaa gtactcgttt cggtcattta taggtgcggt gtttggagaa atagggttca
    17281 atcttagccc attcttgatc gtttaaatca gtatcatata ctttgcgtgt cataactcta
    17341 gtttaacatt ttttgtgaat acaggttcta aataatcgac cacgaaaatt tcttaagtgg
    17401 aaaacgcctt atgaagtatg ctacgggaaa gttatgcact taatttgaca attcaagatg
    17461 taaaaatat
//
LOCUS       DAVKBK010000033        17002 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVKBK010000033 DAVKBK010000000
VERSION     DAVKBK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.033"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            331..1377
                     /gene="pheS"
                     /locus_tag="VWX69_001312"
     CDS             331..1377
                     /gene="pheS"
                     /locus_tag="VWX69_001312"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU9192651.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1377..1886
                     /locus_tag="VWX69_001313"
     CDS             1377..1886
                     /locus_tag="VWX69_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192652.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1963..4365
                     /locus_tag="VWX69_001314"
     CDS             1963..4365
                     /locus_tag="VWX69_001314"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU9192653.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(4433..5434)
                     /locus_tag="VWX69_001315"
     CDS             complement(4433..5434)
                     /locus_tag="VWX69_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9192654.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5590..6036
                     /locus_tag="VWX69_001316"
                     /pseudo
     CDS             5590..6036
                     /locus_tag="VWX69_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6162..6428
                     /locus_tag="VWX69_001317"
     CDS             6162..6428
                     /locus_tag="VWX69_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9192655.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            6689..8938
                     /gene="metE"
                     /locus_tag="VWX69_001318"
     CDS             6689..8938
                     /gene="metE"
                     /locus_tag="VWX69_001318"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU9192656.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9002..9868
                     /gene="metF"
                     /locus_tag="VWX69_001319"
     CDS             9002..9868
                     /gene="metF"
                     /locus_tag="VWX69_001319"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU9192657.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10553..12766
                     /gene="pnp"
                     /locus_tag="VWX69_001320"
     CDS             10553..12766
                     /gene="pnp"
                     /locus_tag="VWX69_001320"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU9192658.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDLEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            12782..13399
                     /gene="cysE"
                     /locus_tag="VWX69_001321"
     CDS             12782..13399
                     /gene="cysE"
                     /locus_tag="VWX69_001321"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU9192659.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13411..14295
                     /locus_tag="VWX69_001322"
     CDS             13411..14295
                     /locus_tag="VWX69_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192660.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14382..15725
                     /locus_tag="VWX69_001323"
     CDS             14382..15725
                     /locus_tag="VWX69_001323"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU9192661.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15718..16104
                     /locus_tag="VWX69_001324"
     CDS             15718..16104
                     /locus_tag="VWX69_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU9192662.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16108..16992
                     /locus_tag="VWX69_001325"
     CDS             16108..16992
                     /locus_tag="VWX69_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU9192663.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         5047 a         3323 c         3893 g         4739 t
ORIGIN      
        1 tcatcttatt tcaatccgct ataaagttag ataagaataa gctaacaagc agaagtaaga
       61 taggtcttgc aagaatggta aaaatctgat aaactaagtg gtaattgaat agaaatctga
      121 aagactagta gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat
      181 atgaaagctg ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga
      241 tgaaaacgga tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct
      301 ttttatctac gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg
      361 cttcgcgaag aaacgctgac tagcttgaag cagattactg ctggaaatga aaaagagatg
      421 caagatttgc gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg
      481 atgaaagatg tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt
      541 gatgtcttga cagctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg
      601 gctcaactgg ctagcgagag tatcgatgtg acgcttccag gtcgtccagt tgcgactggt
      661 caccgtcacg ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt
      721 tatcaagtcg tggatggttt tgaagtggag caagactact ataactttga acgtatgaac
      781 cttccaaaag accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc
      841 ttgctccgta cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct
      901 aaaggtcctt tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg
      961 acccacagtc accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg
     1021 gctgatcttc aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa
     1081 attcgtttgc gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct
     1141 tgcttcaagt gtggtggaga aggctgtaac gtatgtaaga aaacaggttg gatcgaaatt
     1201 atgggagccg gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta
     1261 tactctggtt ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc
     1321 aacgatatcc gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga
     1381 ttagaaaagt agaaatggca gatgttgagg tgttggctaa aattgccaaa caagcctttc
     1441 gtgaaacctt tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaggctt
     1501 atagtctgaa aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta
     1561 tgcatgagga ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga
     1621 gagaattaga ggacgctttt gaaattcaac gcctctatgt gctacaaaaa ttccaagggt
     1681 ttggactagg taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt
     1741 cttgggcttg gctaggtgtt tgggagcata atacaaaagc tcaagcgttt tataatcgat
     1801 atggttttga aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt
     1861 ggttactgag aaagaaatta aggtaagaag aggattcttc tattgaaatg ataggaaagg
     1921 aaaagaacca gtgtggcaat ggtcattctg gagaactaaa ttatgcttat atcttataaa
     1981 tggttaaaag aattggtgga cattgatgtg ccatcacaag agttggctga aaaaatgtca
     2041 actacaggaa tcgaggtaga gggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc
     2101 gtcggtgagg tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcaggtt
     2161 aacgttggcg aagaagagcg tcagatcgtt tgcggtgccc caaatgtgcg tgctgggatc
     2221 aaggtcatgg tggctcttcc aggagctcgt atcgctgata actacaaaat caaaaaagga
     2281 aaaatccgtg gtttggagtc acttggaatg atctgttcac ttggtgaatt gggaatttct
     2341 gactcagttg tgcctaagga attcgcagat ggcatccaaa tcttgcctga agatgccgtg
     2401 ccaggtgagg aagtcttttc ttacctagac ttggatgatg aaatcatcga actttccatc
     2461 acaccaaacc gtgcagatgc cctttctatg tgtggagtgg ctcacgaagt ggcagccatc
     2521 tatgacaagg cagtcaactt taaagaattt actctaacag aaactaatga agctgcggca
     2581 gatgcccttt ctgtcagcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     2641 gacaatgtga ccatcgcacc aagtccacaa tggttgcaaa atcttctcat gaacgaagga
     2701 atccgtccca tcaataacgt agtggacgtg accaactaca tcctgctcta ttttggtcaa
     2761 ccaatgcatg cctttgactt ggataacttt gaagggactg acatccgtgt gcgtgaagcg
     2821 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     2881 ctagtcatca ctgtcgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     2941 acagaaatct ctgaaaaatc tagtcgtgtt gtccttgaag ctgctgtttt caatggcaaa
     3001 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     3061 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     3121 gaacttgcag gtgcgacggt gcgtaagggc atcgtttcag cgggtgagct tgatacttca
     3181 gatgtagaag tttcttcaac ccttgctgat gttaatcgtg tcctcggaac tgagctgtct
     3241 tatgctgatg tagaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     3301 agctttacag tcagagtccc acgtcgtcgt tgggatatca caatcgaagc tgacctcttt
     3361 gaagaaattg ctcgtatcta tggttatgac cgcttgccaa ctagtctacc aaaagacgat
     3421 ggtacagcag gtgaattgac agccacacaa aaactccgcc gtcaagttcg tactattgct
     3481 gaaggagcag gtttgacaga aatcatcacc tatactctaa caactcctga aaaagcagtt
     3541 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     3601 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     3661 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     3721 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     3781 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taagggaatc
     3841 cttgaagccc tatttactcg tttgggactc caagtaacct atacagcaac atctgaaatc
     3901 gctagccttc atccaggtcg tacagccgtg atttcattcg gtgaccaagt tcttggtttc
     3961 cttggccaag tgcatccagt cactgccaag gcttacgata ttccagaaac gtatgtggct
     4021 gagcttaacc tttcagctat cgaagctgcg cttcagccag cgactccatt tgtagaaatc
     4081 accaaattcc cggcagtcag ccgtgacgtt gcccttctcc tcaaggcaga agtgactcat
     4141 caagaagttg tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     4201 tttgacgtct tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     4261 accttccaaa atccagaaga tagcttaacg gacgaagaag tcgcacgcta tatggaaaaa
     4321 atccaagcat cgctcgaaga aaaagtcaat gcagaagtgc gttaaacgat agtatgatac
     4381 aaattccccc tctagtttat gaacactaga ggggtgattt tatataaaat aattaaaatg
     4441 tgatttctgt aaaaatacat ctatgatcag agttttgaaa acttacaatg tctaaatctt
     4501 taacatagta gtggttttta ggcaataaaa tatgatctat tgttgcatta aaaagttttg
     4561 gactttggct attccaagtt cctctttcaa aaggtggcag tacatttaat gcgtccctat
     4621 gagagcttat ttttgcaagt gctccatgac gcatagttgc attaaaatca cctgcaataa
     4681 tagcctttgg atattttgaa gccaattgat tatgaatgat gtttaagtct tgcttccaga
     4741 tttccattaa acctggcaga ggaggagcag tatgcaaggc aatgatatct ggtatatttt
     4801 gttttctcga atgtaataca attgtcccga accgtgttgt atgaaaagtt ttagcttctg
     4861 tatagaaacc ataacttttc ttgacaatca cagtcacagg agctattcca ctattggtag
     4921 gtggagaagt gaaaatatca tagttggcca tagaaagtcc aacttgatga aacaatagtt
     4981 tgattctctg gttttcttgc tcacctctga tattggtagc tagttcaggg aatatagcca
     5041 tatcggcgtc aaaatggcta aaaattcgct caatatgttg tgcttctatt tgattagcga
     5101 cgttccaagt tactaatttt aaggttttag tcttatttga tgcagaagaa agggttttat
     5161 ctgttccgaa taatagtaat atgagcgata gtaagagcaa aatgccagag taaaaccgta
     5221 tttgtttatt tttcttgtaa aaagataggg aaaaaaatac gaaacttaaa atagcagcca
     5281 tagttgcagt agctaagggg aaggcataaa tctgtgccaa gataggttgg gtagatagcc
     5341 aaatgttaag attagaagat gggaaaaaag aataagttat aatagggata gaaaagagaa
     5401 tgaccgaaag ggcagagaga aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg
     5461 ttgctcggag ctaatgtgac tttgtgactt tacttgattg atattctttt tcttgtcttc
     5521 ctcatagatt aagtacaacc caagtaaaaa aagtccaatt taagattgaa atgattaaaa
     5581 ggcacagaaa tgcaagacaa ttatactaca aaaggcaaac atttgacaat cgatagccgt
     5641 cgcttaatcg aacgatggaa aaaagaagga aaatcaaata gagaaattgc ctctctactt
     5701 ggaaaagctc ctcaaactat ccatactgaa atcaagtatg ggacagtccg acaatgtctt
     5761 ggaaaagggc gcttcaaaga gatttattct gccgactacg ctcaacagtc ttatgaaaat
     5821 aatcgcaagc actcggtcaa gaaatcaagc ttgactaaga aactaaagga aaagattctc
     5881 cactatcata accaaaaatt ttcgcctgaa atgatggtga tggctaaagg ggttaacgtg
     5941 ggaatttcaa ccatttacta ttggattcat cgtggaaaat tggggttaag caagcaggat
     6001 ctgctttatc ctagaaaagg aaaagcgctt aagaaatagg ctagcaccaa ctttaaaccc
     6061 gctggtcaat ctatcgaatc ataattcgct cattttttta aaaatacata gacgtaaaaa
     6121 aaagagggtt aagtgatgaa gaatagtgct attgggagta attggaagga tgtccatctg
     6181 agctctttag caaggaggaa atccttgaaa gtgatatgcg agtggctatc atgagcgagt
     6241 tgattgaggc taggtatgaa caaggaatca gtcagaaaaa gctggaagaa gtcagtggaa
     6301 taagccagcc tgtcatagct aggatggaga caggagagag cagtcttcag ttggatacgg
     6361 tcttaaaagt tctaaccagt ctaggaaaga cactagcagt cgttccactt gaacagggga
     6421 aaagttgact agaatcagtt atagtctttt ctaataacag gtcatagtca cttataagaa
     6481 ttactaataa catgttttag tattctaatt ggaatatagc tgtaaagtaa gaattacaaa
     6541 ggatttgaga cgtttgcttc aagtcttttt cttttgtccg aaacagatat atagtttcaa
     6601 actatatcaa accctaattt tttacaatta tacagacgct ttcttttctg ttaagatagt
     6661 ttcaacaaca aattttggag gacacatcat gtcaactaca atcatcggtt tccctcgttt
     6721 gggcgaattc cgtgaattaa aatttacaac tgaaaaatac tttagaaaag aaatctcaga
     6781 agaagaactt ttagcagcag caaaagactt gcgtgctaaa cactggaaca ttgtcaaaga
     6841 aaaaggcatc actgaaattc catcaaatga cttttctcac tatgataact tcctagatgc
     6901 ggctttcctt ttcaacgtgg tgcctgcatc cgttcaaaac ttggacttgt ctgaccttga
     6961 gcgctacttc gctttgggac gtggttacca gggagaaaaa ggggacgttc gcgcccttcc
     7021 aatgaagaaa tggttcaaca ctaactacca ctacatcgtt cctaaatttg aaaaagacac
     7081 tcaagtaaaa ttggctggtc acaagatttt cgatgagttc caagaagcaa aagaacttgg
     7141 attgaacact cgtcctgttc ttgtaggtcc attcactttc cttcaattgt cagactttga
     7201 agaaggcgtg aaagcagacg acttcgtaga tagcttagtg gttgcttacc aagaagtttt
     7261 tgctaaattg gctgaacttg gtgcgactcg catccaattg gatgaagcgg ctcttgtaaa
     7321 agacttgaca gctgaagaaa aagctctctt cttgaacctt tacaacaaac tcttggctga
     7381 caaaaaaggt cttgaagtct tgcttcaaac ttatttcggt gatgttcgtg acgtatacgc
     7441 tgaccttgta aacttgccag tagatgctat cggtcttgac tttgttgaag gtaagaaaac
     7501 tcttgaactc gttaaaggtg gcttcccagc tgacaagact ctctatgtag gtattgtcaa
     7561 tggtaaaaac atctggcgca acaactacga aaagagcttg gctgttcttg agcaaatccc
     7621 agctgaaaac atcgttttga caagctcttg ctcacttctt catgtgccat ttacaactgc
     7681 taatgaagaa tttgaaccag cactcttgaa ccactttgcc tttgcagttg aaaaattgga
     7741 tgaaatccgt gacttggatg ctatccgcaa tggtcaaggt tcagaagctc ttgcagccaa
     7801 caaagaactc tttgcgactg agcgtgttgg tgaaaatgct gaacttcgtg cgcgtatcgc
     7861 tggcttgaca gacgcagact acactcgttt gccagccttt gcagaacgtg aagctatcca
     7921 agaagaagct ttcaaacttc cagctcttcc aacaacaacg attggttcat tccctcaaac
     7981 aaaagaagtt cgtgccaaac gtttggctta ccgtaaaggt gaattgtctc aaaaagagta
     8041 cgatgctttc cttgctgaaa cgattgacga atggatcaag tggcaagaag atattgactt
     8101 tgatgtcctt gttcacggtg aatttgagcg taatgacatg gttgagtact tcggtcaaaa
     8161 cttgtcagga tacctcttct ctaaaaatgg atgggtacaa tcatacggta tgcgtggggt
     8221 aaaaccacca atcatctggg gtgatgtcac tcgtcttaac cctatcactg ttaaatggtc
     8281 tagctatgca caaagtcgta caaacaaacc tgttaaaggt atgttgactg gacctgttac
     8341 catccttaac tggtcattcc cacgtgaaga catctctatc aaggattcaa ctcttcaaat
     8401 cgcccttgct atcaaggatg aagtacttga ccttgaagct gctggtgtga aaatcatcca
     8461 aatcgacgag gctgctcttc gtgaaaaatt gccactccgc cgtagcgact ggtacgaaga
     8521 ctaccttgac tgggctattc ctgccttccg cttggtacac tcaacagtag cgccagacac
     8581 acaaatccac actcacatgt gttactcaga atttacagat atcatcccag ctatcgataa
     8641 catggatgca gacgttattt cctttgaagc tagccgttca aaccttgaaa tcttggacga
     8701 actcaaagcg aaaaacttcc aaacagaagt gggacctggg gtttacgata tccactcacc
     8761 tcgtgtacca aatgaaggcg aaatcgacaa cacaatcgaa gccatccttg ctaaagtgcc
     8821 aagcaagaaa gtttggatca accctgactg tggtttgaaa acacgtggta tcccagaaac
     8881 aaaagaaagc ttgatccgcc ttgttgaagc agctaaagct gcgcgtgaga aattgtaaga
     8941 ttggatttct ctccatacag tggttgttca aaaagaaatc aactagaaaa ggttattaca
     9001 tatgtcacgc caaacaccgt cactctcatt tgaagtgttc cctccaaacc cagccgtggg
     9061 taatggtaac attatttcag ccttgcagga tatgcaggag ttggctcccc attttatcag
     9121 tgtaactgcc agcaataata aatttaatat caaggaaacg acggttcgtt tggctgactt
     9181 tatccaaaat gacttggcga ttccgaccat tgcccacttg ccagctattt atctaactaa
     9241 ggacaaggtt gctgaaacta ttgctgactt ggacaaagtt ggggtgcaga aaatcttggc
     9301 tcttcgtggg gatattattc cagacgtaga accacaaaag gatttccgct atgcaaccga
     9361 cttgattgag tttatcaagg aacaagcccc tcactttgat attattggag cttgctatcc
     9421 agaagggcat ccagattcgc caaatcagat ttcagatatt caaaatctta agaagaaagt
     9481 ggatgcaggc tgttcgagcc tcgtaactca gctcttcttt gataatgagc gcttctatga
     9541 ttttcaggac aagtgtattt tggctgggat tgatgttccc attcatgcag gaattatgcc
     9601 aattctgaat cgaaatcagg ctctccgact cttgaagact tgtgagaata tccatcttcc
     9661 acgcaaattt aaagccatct tagacaagta tgagcatgac cctgagtcgc tcagagcagc
     9721 aggacttgcc tatgcagtgg accaaatcgt ggacttggta actcaggatg ttgccggtgt
     9781 gcatctctat acgatgaata atgctgatac agcaaaatac atccatcaag caacccatgc
     9841 cttgtttaat caccagtctc taggataata aaagcaaacc attcttctca ggtgagggga
     9901 atggttcctt tttaatggta aagacctcac tttttaagaa aaatatgata aaataaattc
     9961 tgtacgtact tgatacaaag atgaaggtat taaataatac aatgcattta aactgtaaga
    10021 tttaacgaca cgagtgagtc aaatcgatgt tatttgacga gagagttagt aaagcattta
    10081 gctaatcgcc cgatagcgat tagcgtgaaa gctttagata ctttagtatt aaacctttct
    10141 aatgatgtat cttgaaaact gaacttgcct acaactctgt ggaaaaagat aaatctccct
    10201 aggagcagtc gctccgtcgt tcgatttcct attttccttt gagttgcttg acggcttggt
    10261 atcttgatga cttgaatttt ggtctcattt cttaggaaaa aagataagct tcctagcact
    10321 cgtcgagtgc gacgtcacct tcctattttt ctacagaaat gttcggcaag ccgaaccgtc
    10381 caaaatatct tgtgtaattg aacacggccg aaaagctgtg taaaaaagat aaactgtctt
    10441 gtcttcatcg aagacttcgt cagtttccta tttttacttt gcttttgacg tccttggtat
    10501 cttgatcttt gtaggcaagg cgtataattt catcaatcca aaggggatta aaatggcaaa
    10561 acaagtgttt caaacgactt ttgcgggtcg tgagttaatt gtagaaactg gtcaggttgc
    10621 taagcaagca aatggctctg ttgtcgtacg ttacggtgag tcaactgtct tgactgctgc
    10681 cgttatgtct aagaaaatgg caactgggga tttcttccca ctccaagtca actacgaaga
    10741 aaaaatgtat gcggctggga agtttcctgg tggctttatg aaacgtgaag gacgtccttc
    10801 aacagatgcg accttgacag cgcgtttgat tgaccgtccg attcgtccta tgtttgcgga
    10861 aggtttccgt aatgaagtcc aagtcatcaa tacagtgctt tcttatgatg aaaatgcgtc
    10921 tgcaccaatg gctgctatgt ttggttcatc tttggcactg tctatttcag atattccatt
    10981 tgacggacca attgctgggg tacaagtggg atatgtagat ggccaaatca tcatcaaccc
    11041 aagtcaagaa caagcagagc aatctcttct tgaattgaca gtagctggaa ccaagcacgc
    11101 tatcaacatg gtagagtctg gtgctaaaga attgtcagaa gaaatcatgt tggaagcgct
    11161 ccttaaaggg cacgaagctg tcaaagaatt gattgccttc caagaagaaa tcgttgctgc
    11221 tgtcggtaaa gaaaaagcag aagtggaatt gcttcacgtg gatgctgaat tgcaagctga
    11281 aatcattgca gcctacaaca gtgacctcca aaaggcagtt caagtagaag agaaattggc
    11341 ccgtgaagct gcgactcaag tagtgaaaga ccaagtgact gccgtttacg aagaaaaata
    11401 tgcggaccac gaagaatttg accgtattat gcgtgatgtg gctgaaatct tggaacaaat
    11461 ggaacacgca gaagtgcgac gtttaattac agaagacaag gtgcgtcctg atggtcgtaa
    11521 ggtcgatgaa atccgtcctt tggatgcggt tgtcgacttc cttcctcgtg tgcacggttc
    11581 aggtctcttc actcgtggac aaacgcaagc cctttctgtc ttgaccttgg ctccgatggg
    11641 agaaactcaa atcattgatg gtttggatct ggagtacaag aaacgcttta tgcaccacta
    11701 taacttccct caatattctg taggggaaac aggtcgttac ggtgcgccag gtcgtcgtga
    11761 aatcggtcac ggtgcccttg gtgagcgtgc tcttgctcaa gtcttgccaa gcttggaaga
    11821 attcccatac gctatccgtc tagtagcaga agttttggaa tcaaacggtt cttcatctca
    11881 agcttctatc tgtgcgggaa ctcttgccct tatggctggt ggtgtgccaa tcaaggcgcc
    11941 agtagctggt attgctatgg gacttatctc agatggaaat aactacacag tattgacaga
    12001 tatccaaggt ttggaagatc actttggaga tatggacttc aaggttgcag gtactcgtga
    12061 tgggattaca gcccttcaaa tggatatcaa gattcaaggg attactgcag aaatcttgac
    12121 ggaggctctt gctcaagcca agaaagcgcg ttttgaaatc cttgatgtca ttgaagcaac
    12181 cattccagaa gttcgtccag aattggctcc aactgctccg aaaattgata cgatcaagat
    12241 tgatgtggac aagattaaga ttgtcatcgg taagggtgga gaaaccatcg acaagattat
    12301 cgctgaaaca ggtgttaaga ttgatataga cgaagaagga aatgtgtcta tctactctag
    12361 tgaccaagat gctattaacc gtgccaaaga aattattgct ggtttggttc gtgaagccaa
    12421 agtggatgaa gtttaccgtg ctaaagtcgt tcgtatcgag aaatttggtg cctttgttaa
    12481 cctctttgat aagacagatg cccttgttca tatctctgag atggcttgga ctcgtaccaa
    12541 tcgtgtagag gatttggtag aaatcgggga tgaagttgat gttaaggtta tcaaaattga
    12601 tgaaaaaggc cgtatcgatg cctctatgaa ggctcttcta cctcgtccgc caaaacctga
    12661 gcatgatgaa aaaggtgaaa agtctgagcg ccctcaccgc ccacgtcatc aaaaggatca
    12721 caaacctaag aaagaattta cagaaacacc aaaagattca gaataagaaa aggagaaatg
    12781 tatggggtgg tggcgcgaaa ccattgatat tgtaaaagaa aatgatccag cggcccgcac
    12841 cactttggag gttttgctga cttatccagg tgtcaaggcc ttggcggccc accgtctctc
    12901 gcattttctc tggaagcacg gcttcaaact attagctcgt atgtacagtc agttttggcg
    12961 cttttggact cagattgaga ttcatccagg agcccagatt gattcaggtg tttttattga
    13021 ccatggttct ggtctggtga ttggagagac agcgattgtt gaaaaaggcg ttcttctcta
    13081 tcacggagtg actctcgggg gaacagggaa agactgtggc aaacgccatc cgactgtacg
    13141 aaagggagcc ctcatatcag cccatgccca agttatcggg cctgtggaaa ttggtgaaaa
    13201 tgccaaggtc ggtgctgcag cagttgtcgt agcagatgta cctagtgatg tgacggttgt
    13261 cggtattccg gccaagattg tccgtcttca tggtaagaaa gatgagcctg ttattcacga
    13321 agtcgaagaa aaacgggagt attatgtcaa taaactcgag caggctaaag atgccagtca
    13381 cagatcgtct ggtttgtaga ggatacctat atgattcaag caagaaacaa gttaagccaa
    13441 gaggagctat ctgaggcgaa aaaagtaatt aactgttgcc aaaactatga cggtacctat
    13501 cgcgatccct atctctctaa catgcttaat tttgacccaa acatgcccgc ctttttcctt
    13561 tattatgaaa aaggcaaact tgttggttta ttaactgtct atgcagatga ccaagatgta
    13621 gaagtgacga tattggttca tccaggtcat cgccgtcagg ggattgcgcg tgcattgttt
    13681 actagttttg agagagaaac agcttctttc cccattcggt cagtcacttt tcagacagaa
    13741 cgtatttttt tagagaatca tcctgacttt gccagtaact ggggactaat cgaggatgaa
    13801 gagacagaaa cttggttagg taaggataga agaccttatc cgttagcaaa tgtttcccat
    13861 cttgaagttt tgttagcaga tagttcgtat caggatcaaa ttagtcaatt aaaatttcag
    13921 gcattttcag aggaacatga atcgagagaa gttgtggata gatatgtcgc tgaagctctg
    13981 aaggatccag aaagtcgctt atatattttg ttaaaagacg gtcaggttat tgggacttgc
    14041 acggtagatt tatcgactaa tacgaattac ttctacggtt tagcaatatc ggaacctgaa
    14101 cgtgggaaag gctatggaag ctacttagca aaatccctcg tcaaccaact aattgagcaa
    14161 aatgacaagg aatttcagat tgcagtggaa gatagcaatg taggtgccaa acgtttgtat
    14221 gaaaaaattg gctttgtcaa acagacacag gtggtttatc tgaatgagaa aggagcaagg
    14281 gattccgaag tgtagagaca ttcggactga aatttacttg agctcttagt ttagtgatga
    14341 aactaacagt tcttggattt tagctttcct gattatgatt tatgattaaa atctatgaca
    14401 ccatgtctcg tgatttgcga gaatttgtcc cgattgagga cggcaagatc aagatgtatg
    14461 tttgtgggcc aaccgtgtac aactatattc acgtgggaaa cgcccgttcg acggtagctt
    14521 ttgatacgat tcgtcgctat tttgagtacc gtgggtataa ggttgcctat atttccaatt
    14581 ttacagatgt ggatgataag attatcaacc gtgccaggga agaaggcatc acacctcagg
    14641 aggttgcgga taagtacatc gctgcctttc gtgaggatgt gacggcctta ggcgtgaaac
    14701 ctgcgactcg ccatccgcgt gtagtggagt ttatggcaga catcatccgt tttgtggaag
    14761 acttgatcga gaaaggcttt gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa
    14821 aatcccacaa ctatgctaaa ttggctaata aaaccttgga agatttggag ctaggtgctt
    14881 caggtcgtac cgatgaagaa acggctcgta aggaaaatcc tgtagacttt gctctatgga
    14941 aatcttccaa accaggtgag atttcttggg atagtccttg gggacctgga cgtccgggtt
    15001 ggcatattga gtgttcagtc atgtcgacag agattttagg tgataccatt gatatccacg
    15061 gtggtggagc tgacctagag tttccacacc acaccaatga aattgcccaa tctgaagcta
    15121 aaacaggcaa ggcttttgct aactactgga tgcacaatgg ctttgtcaat atcgacaatg
    15181 tcaaaatgtc taagtccttg ggtaacttca ttacggtaca cgatgccctt aaaactcttg
    15241 atgggcaagt acttcgtttc ttctttgcga cccagcacta ccgtaagcct atcaacttca
    15301 cggaaaaggc agttcgcgat gccgagacca atctcaagta tctgaagaat acttacgaac
    15361 aaccatttac aggaaacgtg gatgcccaag agttacaaaa ctttaaagat aagtttgtag
    15421 cagctatgga tgaagatttt aatgctgcca acggtatcac agttgtcttt gaaatggcca
    15481 aatggatcaa ctcagggaac tatgatgcaa gtgtcaagca agctcttgca gatatgttag
    15541 aaatttttgg aattgtcttt gttgaggaag ttttggatgc agagattgaa gacttgattc
    15601 aaaaacgcca agaggcgcgt gccaatcgtg actttgagac agcagaccaa atccgtgacc
    15661 aattggttac tcaaggaatt aagctccttg ataccaagga tggagtgagg tggacacgtg
    15721 attgatgtca atctcattaa cgggattgcg ctagcctttg agggagatgc ggtgtattct
    15781 atgtatattc gccgccacct catcctcaaa ggtatgacca agcccaataa actccaccaa
    15841 gaggcgacca agtacgtgtc agccaaggct caggctcgtc tgattgctct catgttggag
    15901 gagcagatcc taacggaaaa agaagaagaa atctacaaac gtggccgcaa taccaatagt
    15961 cacacaaagg ctaaaaatgc agatgtcgtg acttatcgta tgtccacggg atttgaagca
    16021 gttatgggct atctccatat gactgagaat ctggaacgtc ttgagagttt ggtttcatgg
    16081 tgcatccaaa aagtggaggg ctagaacatg agggcaaaag aactacaaga ctggtttcct
    16141 gaggctcgga tttcagacca accagtagag aaagagggct atctcacgct tcctttagct
    16201 tctcagcagt ggattttgct ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt
    16261 gcccttttga cccagcagga gcaggctcgt tcgctaaacc cttggtattc ctatctggtt
    16321 gagggcaagg gacaggcacc gcaagttttt aaaaagattc agttggttta ttgccatctt
    16381 tcttattttc agcaggaaaa tctgacttct tggctagata tgatgcggac tctttttccg
    16441 aattgtcaga cagtgctaca ggtcggagct caggattatg ttttcgtgct tcaacaagac
    16501 aaatacactt ctgtaagaga tattttgagt gatacgattg aagcggttga gtatgacttt
    16561 ggacttcgtc tttctatcat gttgggtcag gtttggtctc agacaggaca tcaagcccta
    16621 tcagacttaa tcaaagctga gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa
    16681 ggtgttcata ctttttctca gctctatctt tggagtatgg gagaaagact cgtggacttg
    16741 aagccaatta aagaatgtct acaccagatg attttggatc aagatcagat tcaggaaatc
    16801 attctctctc tttgggaaaa tagtgctgtt ctcactaaaa cagcccagca actctatctg
    16861 caccgcaatt ctctccaata caagattgat aaatgggaag agttgacagg gcttcagttg
    16921 aaagagttga ccgacctgac cttgtgttat caattgattt taggttcttt gtcaactata
    16981 gttggtttgt aaagaagtta at
//
LOCUS       DAVKBK010000034        16674 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVKBK010000034 DAVKBK010000000
VERSION     DAVKBK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.034"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            87..3437
                     /locus_tag="VWX69_001326"
     CDS             87..3437
                     /locus_tag="VWX69_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9192664.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSLLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(3943..4413)
                     /locus_tag="VWX69_001327"
     CDS             complement(3943..4413)
                     /locus_tag="VWX69_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9192665.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4430..6703)
                     /locus_tag="VWX69_001328"
     CDS             complement(4430..6703)
                     /locus_tag="VWX69_001328"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU9192666.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7050..10151
                     /locus_tag="VWX69_001329"
     CDS             7050..10151
                     /locus_tag="VWX69_001329"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU9192667.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVSYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10234..11241
                     /gene="pfkA"
                     /locus_tag="VWX69_001330"
     CDS             10234..11241
                     /gene="pfkA"
                     /locus_tag="VWX69_001330"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU9192668.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11300..12805
                     /gene="pyk"
                     /locus_tag="VWX69_001331"
     CDS             11300..12805
                     /gene="pyk"
                     /locus_tag="VWX69_001331"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU9192669.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(13540..13765)
                     /locus_tag="VWX69_001332"
                     /pseudo
     CDS             complement(13540..13765)
                     /locus_tag="VWX69_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            14613..15485
                     /locus_tag="VWX69_001333"
     CDS             14613..15485
                     /locus_tag="VWX69_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU9192670.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(15631..15975)
                     /locus_tag="VWX69_001334"
                     /pseudo
     CDS             complement(15631..15975)
                     /locus_tag="VWX69_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            16118..16430
                     /locus_tag="VWX69_001335"
                     /pseudo
     CDS             16118..16430
                     /locus_tag="VWX69_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16434..16674
                     /locus_tag="VWX69_001336"
                     /pseudo
     CDS             16434..16674
                     /locus_tag="VWX69_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
BASE COUNT         5156 a         2840 c         3563 g         5115 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctctgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctttggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggttga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaactagct gcaggctgct caaaacactg ttttgaggtt gtagatggaa
     3781 gctgacgcgg attgaagaga ttttcgaaga gtataaatct tcctaggata aagcaaaacg
     3841 catagtatca agggttttca acacttgata ctatgcgttt tctgatgtta aagactttct
     3901 accaggtttt ttaaaagcat aattgttagt tgtagtcatt tattattctt caaagaaaaa
     3961 tggtggggcg aattttttca gttcttcaaa gcacttttga gcagtatctg catcttcaca
     4021 gatgataaga cagacatcat taccacaaag ggtagcgata gcgtcaggga agctcaaagt
     4081 atcaatgata gaaccaaagg attgagccag tccaggaagg gtttttagta ggacttggtg
     4141 ttgaactggg cgcatccaga caagggcgtc ttccatgtag agttcgagac gtttttccca
     4201 ttttgagatg gaaccattgt taagaacata ataagcgcta tcttcttcgc ggacttttga
     4261 taggttcata tttttgatgt cgcgtgagag ggttgcctgg gttacttgaa tgtcgttctc
     4321 agcaagaagg gcttgcaact cagcctgtgt atgaatcttg ttttttgtga taagagcgcg
     4381 tataagttgg tggcggtgtt ctgatttatt cataataatg taactccttt tagcaaggta
     4441 aggtaagcat ggactgagcg aggtcgacag tcaagtggta gtctgtattg tcacggatgg
     4501 tgatttcaaa gtcagtagta tagaggacta aacggagagt gtctccttct tttagcttgt
     4561 aaatagttgg ctgcagttca aattgaacgt ccatccattc atctgcagta atatcctcta
     4621 ctaacagtaa atcatttcta ttttgtaaat taaggtaacc ttttgtcacg actcgttgtg
     4681 cctctggtct aaatggcaat tcacagagat tttccaacat gtgatagcga ccgttgtcaa
     4741 tggttctagc acttaaaata gctggataag gttgtaggta tttcttttgc ccaaattcta
     4801 gcagttgggc agataagagc cccttgtttg tactggattt gatacgaaga ttgagctgag
     4861 cgcgaccgtt taggtggaga tctttagtca caggaaggtt aatagtaatc tgattggctt
     4921 tcccttgata gagctctgta ttgaaggttt ggtatgtctt accatagcgc tcaaaatcct
     4981 tatctgggta ctggttttga atagcttgct cttcttgacc aagtgagaag gtttcacagt
     5041 tttcttgccc accgaagtta tcaagtgata accaagtctg tggagctgta ttgtcctgcc
     5101 agataacagt aggaagttga aagtctgttt cctgtcctag taatttcttg gtcaataagg
     5161 catttatgga ctcacggaag tcaattgatt gccaattgtt catgtaaaca tgggcaccat
     5221 tatggaaaaa gagatgcttg tgtatatgag taggaagagc atggaacatc tggtaaacat
     5281 gaagtggttt gacattccaa tcctgagaac catgagtaaa gacaacctct gcctttactt
     5341 tatgggcatt gagcagataa ttgcggtcat gccaaaactg attgtagtcc ccagtttttc
     5401 ggtctagctg agctttcact ttttctaagt cagcttggtg agcttcattg ccacggatat
     5461 agtcgccagc taagagatta cgagaatagg ttaactcagc aagggagtca aagtcctcac
     5521 ctggataacc acctgggcta gtcaccagac cgttttcacg gtagtagttg taccatgatg
     5581 aaattcctgc ctcggcaatg ataacttcta aaccatcgac tcctgtagtc gcaagaccat
     5641 tggacatggt acctagatag gaaagtcctg ttgtagcaac ttttccgttt gaccaatcag
     5701 ccttgacttg acgctggcgc gtgtgatcag taaaggcacg gcaacggccg ttaagccaat
     5761 cgatgacatt tttataagcc tcgatttgct ggtagtctcc attagtcatg aaacctgtcg
     5821 agtctttggt accaacacct gagacataga gattggcaaa gcctctcgga aggaagtagt
     5881 cgtttagtgt atagctagag ttgatgtgag ttagcttttc ctcagcctct gctataagct
     5941 cagctttacc ttggggttgg acgagattta gttgaggttt ctctagctca atcttgtgag
     6001 gaagtttaac ctcaagctcg ccctccatct tgtagagagc cttgtcacta gccttgtcat
     6061 tggttccctg atgataaggg ctggctgtca tgatggcagg gatttttcca tcaaaacgag
     6121 ggcgaataat gctaaccttt actaggtctg atagcccttt ttggtcagta tcgacacgag
     6181 actcaacgta aacgacttca cgaatgacat cctggttaga aaaagtagcc aaactcttgc
     6241 cgttaaagta gtggtagtca ttatcctccg gaataagacc atcactaaca agttggtcga
     6301 taagagtatt tccttttttg gtgcgagtat tgagtaactg atagagattt tcaatcaagt
     6361 caccatatat aatgggaaat ccagtttctt tacgaaaaac gtcactatct tcgaagtcaa
     6421 ccaaataaga aaagcctaaa agttgaaaag caacagtata aaaaatatct gctgtcagtt
     6481 catcttctga ttgaaaaaat gtcagcaggt ctgttttttt atcagctgct aggatagaaa
     6541 gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg taaaaaggtt tcaagtgagt
     6601 ctttgtgatt ggctgtattt tgtaaatcaa agccacattt ttttagttca gataagacat
     6661 tttcttttgg aaaattgata taactatatt gattaaaacg catagaacct ccatatagaa
     6721 tgatagttaa ggttattata tcaaaaaaaa agcagaaagg gaattgttaa cttcaaaagg
     6781 aaataatcca ataaaaatga ataaagtact aaattcaata tagagaacag agtaacaata
     6841 agaataaata gatagggtat aaaagttcta ggagatttat attatatgct ttctattttt
     6901 atatacaata tagtataaat ataaaaatga tgacaaaaat acaaatgaat agaaaataaa
     6961 ttagtaagct gatgaaattt ttctcaagag aagccattta taggtgaaaa tggtataata
     7021 tagtgagaag gatagaggag aagtgtaaat tgatcgcaca actagataca aaaacagtct
     7081 atagttttat ggaaagcgtc atttcgatcg aaaagtatgt gagagcagct aaagaatacg
     7141 gctacactca tttggctatg atggatattg acaatcttta tggcgctttc gactttctag
     7201 agattacaaa aaaatacggc attcatcctt tgctagggct tgaaatgaca gtgtttgtag
     7261 atgatcagga agtgaatttg cgctttttag ctctatctag tgtgggctat cagcagttga
     7321 tgaagctttc gacagccaag atgcaggggg agaaaacttg gtcagtcctg tcccagtacc
     7381 tggaggatat cgcggtcatt gtgtcttatt ttgatagagt tgagtcgtta gaactaggct
     7441 gtgattacta tataggggtt tatccagaaa cactagcaag cgaatttcat catcctatct
     7501 tacctcttta tcgggtcaac gcttttgaaa gcagggatag agaagttctt caagttttaa
     7561 cagcgattaa agaaaatcta ccgctcagag aagttccctt gcgttcgaga caagatgtct
     7621 ttatatcagc aagttcttta gagaaactat tccaagagcg ttttccgcaa gctttggaca
     7681 atttagaaaa gcttatttca ggcatttctt acgacttgga tactagtctg aaactgcctc
     7741 gttttaatcc agctagacca gcagtagagg agttgagaga gcgtgctgaa ctggggcttg
     7801 ttcagaaggg gttgactagt aaagaatatc aagatagact agaccaagaa ttgtctgtta
     7861 ttcatgatat gggctttgat gattatttct tggttgtttg ggatttgttg cgttttggac
     7921 gatcgaatgg ctattatatg ggaatgggaa ggggttctgc agtaggcagt ttggtttctt
     7981 atgccttaga catcacgggg attgacccag tagagaaaaa tctgattttt gaacgctttc
     8041 ttaatcgtga acgctatacc atgcctgata ttgatattga tatcccagat atttatcgtc
     8101 cagattttat cagatatgtt ggtaataaat atggtagtaa acatgcggca caaatcgtta
     8161 ctttttcaac ctttggagcc aagcaagctc ttcgagatgt cttgaaacgc tttggtgtgc
     8221 cagagtatga attatctgca attactaaga aaatcagttt tcgtgacaat cttaagtcgg
     8281 cctatgaggg caatctccag tttcgtcagc aaatcaatag taagttagaa taccaaaaag
     8341 cttttgagat tgcttgcaag atagagggct atccaaggca aacctctgtc catgcggctg
     8401 gtgttgtaat tagtgaccaa gatttaacca actacattcc tctaaagtat ggtgatgaaa
     8461 ttccactgac tcagtatgat gctcatggag ttgaggctag cggacttttg aagatggact
     8521 ttctgggact acgaaatttg acctttgtcc agaagatgca agagttgctt gctgaaacag
     8581 aaggtattca tctgaaaatt gaagaaatcg atttagaaga caaagaaacg ttagctttat
     8641 ttgcctctgg taatacaaaa ggtatctttc aatttgagca accaggtgcc attcgtctgc
     8701 ttaagcgtgt gcaaccagtc tgttttgaag atgtcgtcgc gactacttct ctaaatcgac
     8761 caggtgcaag tgactacatc aataattttg tggcaaggaa gcatgggcag gaagaagtga
     8821 ctgttctaga ttcagctctg gaggatattt tggctccaac ttatggcatt atgctctatc
     8881 aggagcaggt tatgcaggtt gctcagcgat ttgctggatt tagtcttggg aaggccgata
     8941 ttttgcgtcg agctatgggt aaaaaggatg cctctgctat gcatgagatg agggcttcct
     9001 ttattcaagg ctccatagaa gcaggccata ctgcggaaaa agcagagcag gtttttgatg
     9061 ttatggagaa gtttgcaggt tatggattta atagatctca tgcctacgcc tactcagcct
     9121 tggccttcca gttggcttat ttcaaaacgc attatccagc cattttttat caggtcatgt
     9181 taaattattc caacagtgat tacttaatag atgcacttga agcaggtttt gaagtagcct
     9241 ctctatccat caatactatt ccctatcacg ataaaattgc caacaagtct atctatatag
     9301 gtttgaaatc gattaagggg ctcagcaagg acttggcgct ttggattatt gaacatagac
     9361 cttattctaa cattgaagat tttatagcta aattacctga gaattatctg aaacttcctc
     9421 tgctagaacc tttggtaaaa gttggtcttt tcgattcatt tgaaaaaaat cgtcaaaaag
     9481 tatttaataa cttagctaat ctatttgaat ttgtgaaaga gttgggaagt ttgtttggag
     9541 atgctattta tagttggcag gaatcggaag attggacgga acaagaaaaa ttttatatgg
     9601 aacaagagct tttagggata ggtgtcagca aacatccact acaagctatt gcaagtaagg
     9661 ctatttaccc gattacccca atcggaaatt tgtcagaaaa tagctatgct attattttgg
     9721 ttgaagttca gaaaataaaa gtgattcgta ccaaaaaggg tgaaaatatg gccttcttac
     9781 aggcagatga tagtaagaaa aaattggatg tcactctctt ttcagactta tatcgtcagg
     9841 ttggacagga aataaaagag ggagccttct actatgtaaa aggaaaaata caatcacgtg
     9901 atggccgtct gcaaatgatt gcacaagaaa taagagaagc agttgctgaa cgcttttgga
     9961 tacaggtgaa aaatcatgaa tcggatcaag aaatttcacg cattttagaa caatttaaag
    10021 gcccaatccc agtcatcatc cggtatgaag aggaacagaa aaccatcgtt tctccccatc
    10081 attttgtagc taaatccaat gaattagagg agaaattgaa tgaaatcgtt atgaaaacga
    10141 tttatcgcta aaaatacgga aaatagaaga attttaaaat caaatgtgat ataatcaaga
    10201 agaatgttaa aagaaaaagg agcataaacc aatatgaaac gtattgctgt tttgactagt
    10261 ggcggagacg cacctggtat gaacgctgcc atccgtgcag ttgttcgtca agcaatttca
    10321 gaaggaatgg aagtgtttgg tatctatgac ggatatgctg gtatggttgc cggtgaaatt
    10381 catcccctag atgcagcttc agtaggggac atcatttctc gtggtggtac ttttcttcac
    10441 tcagctcgtt atccagagtt cgctcaactt gaagggcaac ttaaagggat tgagcaattg
    10501 aaaaaacacg gaattgaagg tgtagttgtt atcggtggtg acggatctta ccacggcgct
    10561 atgcgtttga ctgaacatgg cttcccagct attggtcttc caggtacaat cgataacgat
    10621 atcgttggta ctgactttac aatcggtttt gacacagcgg ttactactgc catggacgct
    10681 atcgataaga ttcgtgatac atcatcaagt caccgtcgta cttttgtaat cgaagttatg
    10741 ggacgtaacg ctggtgatat cgctctttgg gctggtattg caactggtgc tgatgaaatc
    10801 atcatccctg aagcaggctt caagatggaa gatatcgtag caagcatcaa agctggttat
    10861 gaatgtggta aaaaacacaa tatcatcgtc ttagctgaag gtgtgatgtc agcggctgaa
    10921 tttggtcaaa aacttaaaga agctggagat acaagcgacc ttcgtgtaac agaacttgga
    10981 catattcaac gtggtggttc tccaactgcg cgtgaccgtg ttttggcgtc acgtatgggt
    11041 gcacatgctg ttaaacttct taaagaaggt atcggtggtg ttgcggttgg tattcgtaac
    11101 gaaaaaatgg ttgaaaatcc aattcttggt actgcagaag aaggggcatt gtttagcctt
    11161 actgcagaag gtaagattgt ggttaacaac ccgcacaaag ccgatattga gctatctagc
    11221 ttgaataaga gcttgtcata atttacaatt tagttaataa gaccaaaaag gtcatatata
    11281 taaaggagtc acaaaaatca tgaacaaacg tgtaaagatc gttgcaactt tgggtcctgc
    11341 ggtagaaatc cgtggtggta aaaaattcgg tgaggacgga tactggggtg aaaaacttga
    11401 tgttgaagct tcagctaaaa acattgctaa attgattgaa gctggtgcta acacattccg
    11461 attcaacttc tcacacggcg accaccaaga acaaggtgag cgtatggcaa ctgttaaact
    11521 tgcggaaaaa attgcaggta aaaaagttgg tttccttctt gatacaaaag gacctgaaat
    11581 ccgtacagaa ttgttcgaag gtgaagctaa agaatattca tacaaaactg gtgaaaaaat
    11641 tcgtgttgca actaaacaag gaatcaaatc aactcgtgaa gtgattgcgt tgaacgttgc
    11701 tggtgctctt gatatctatg atgatgttga agttggtcgt caagttttgg ttgacgatgg
    11761 taaacttggt cttcgtgtgg ttgctaaaga tgatgcaact cgtgaatttg aagttgaagt
    11821 tgaaaacgat ggtatcatcg ctaaacaaaa aggtgtgaac atccctaaca ctaaaattcc
    11881 tttcccagct cttgctgaac gcgataacga cgatatccgt ttcggtcttg aacaaggtat
    11941 caacttcatc gcaatttcat tcgtacgtac tgcaaaagat gtgaacgaag ttcgtgcaat
    12001 ctgtgaagaa actggaaacg gacatgttca attgttcgct aaaatcgaaa accaacaagg
    12061 tatcgataac ttagatgaaa tcatcgaagc agctgatggt attatgattg ctcgtggtga
    12121 tatgggtatc gaagtaccgt tcgaaatggt tccagtttat caaaaaatga ttatcaagaa
    12181 agtcaatgct gcaggtaaag ttgttatcac tgcaacaaac atgcttgaaa caatgactga
    12241 aaaaccacgt gcaactcgtt cagaagtatc agacgtattc aacgctgtta tcgacggaac
    12301 tgacgctaca atgttgtcag gcgagtctgc aaacggtaaa tacccactcg agtcagtaac
    12361 tacaatggct acaatcgaca agaacgctca agctcttctt aatgaatacg gacgtcttga
    12421 ttcagattca tttgagcgta actctaagac agaagtaatg gcttctgctg ttaaagatgc
    12481 tactagctca atggatatca aattggttgt aactcttact aagacaggtc atactgcacg
    12541 tttgatttct aaataccgtc caaatgctga catcttagca ttgacatttg acgaattgac
    12601 agaacgtggc ttgatgttga actggggtgt tatcccaatg ttgacagatg ctccatcttc
    12661 aactgacgat atgttcgaaa tcgctgaacg taaagcggta gaagcaggtc tcgttgagtc
    12721 aggcgatgat atcgttatcg ttgctggtgt gccagtagga gaagctgttc gcacaaacac
    12781 aatgcgtatc cgcacagtac gttaagaaaa atataaaaac ctatcatatc cagctttcta
    12841 gcctgtatga tgggctcttt ttttgtccag ggggcaaaaa gggggcaaaa ctttcataat
    12901 ggattgatac tcttcgaaaa tcaaattcaa accacgtcag cgtcgcctta ccgtatatat
    12961 gttactgact tcgtcagttc tatctacaac ctcaaagcag tgctttgagc aacctgcggc
    13021 tagcttccta gtttgctctt tgattttcat tgagtatgaa ataagatatg cataaattga
    13081 ttagaaagtc aaatgaattt ctacaaatgt tttagcaatc gcaatctact tgtctagatt
    13141 cgatctgata tattttcgat ttaatgatat ggtatttaaa acctccaaag tagcttgctc
    13201 cattctttta cctacgtgag tctagatgtt atttactgtt ttagcgtttt tgtgttctac
    13261 tctaaccatt atagcattct tctcagctag tgtactaagg agtgtgtgcc tgaaaatatg
    13321 ggaactaagg ggctggttta tcggtttctc tagtttagta tttgcctttt gcaaagtgat
    13381 cttaaatgcc tttctctaaa tttacatatc actattgttt aacaaaatct aatctatttt
    13441 aggtcactta ttcttttttt gaaatgtaga atgaactttt tcaaagtttt tcgaatcttt
    13501 taaaatctgt ttgttttata tcgccattct cccccttttt taattctccc tatatagcct
    13561 gacaactttt ccgatggtac gaatatggtt gctttcgtct aggtggatgt cggagtattc
    13621 gggattgagt ttttttgagg tagccttggc ggagtttctt gacatagtta gtgccgtcta
    13681 cttggaagat gccgatggta ttatagtcaa tctgtggggt attcttgata aataggtagt
    13741 cgctgtttct tatctttggc tccatggact tgctgacgac ataagcgatt gggtcgtagt
    13801 cgtctgggat aatggaaact ccataactaa atcgtcgtcc tgcatcaagc ggctacctgc
    13861 agagataaac tacctaacac gagagtaagt agtctgtctg tagtcgtcca gtctgatgat
    13921 ttttacgata cttcgttttt ctgatcatac agttgcctct cggcataggt cagaacttta
    13981 ccttgtctgg gtggtgcccg ttggtcgtag atagattgga tatcgctagg agaatccttt
    14041 tgaactggag gaaagagggc atcaatcaag ctactgaata ctttaactaa gtcaaatata
    14101 gtatttttct tagtagacct aacccttttt tcataatttc taatggtgtt tttacttata
    14161 cctatcttag tacccaattc ttattgagtc caaccattac tagtctatat tgttttatag
    14221 ttgattgagt ttggaatagt acgctgtagc tgctaaaaca tttctaggaa ttaatttgcc
    14281 tttcctaata gagttgttca tatcttattt caatctacta tatttttcac ctctaacaat
    14341 cgcaatctct tctttatcca tgaacgaaaa cgctttctat ctttgtaagt aaagcatcac
    14401 acgaaatcca cgaaaatgaa aacctttgtt gtgttttcgt aaaaaatttg ttgacagagc
    14461 acgaaacgcc tactataatt aaatcaagtt taaggaaata acaaaaaaac aaatcggagg
    14521 gaaagacgat gaacacatta aatgagaaag taatcaatat ctgtaaagca gtagttaaag
    14581 aaactttaat ccaagacatt taggagaaag aaatgaagaa atcaagaaaa ttagccacat
    14641 taggaatctg ttcagccttg tttttaggct tggctgcttg tcaacaacaa catgctactt
    14701 ctgaggggac gaatcaaagg caaagcagtt cagcgaaagt tccatggaaa gcttcataca
    14761 ccaacctaaa caaccaggta agtacagaag aggtcaaatc tctcttatca gctcacttgg
    14821 atccaaatag tgttgatgca ttttttaatc tcgttaatga ctataatacc attgtcggct
    14881 caactggctt atcaggagat ttcacttcct ttactcacac cgaatacgat gttgagaaaa
    14941 tcagtcatct ctggaatcaa aagaagggcg atttcgttgg gaccaactgc cgtatcaata
    15001 gttattgtct tttgaaaaat tcagtcacca ttccaaagct tgaaaagaat gaccagttgc
    15061 ttttcctaga taatgatgcg attgataaag gaaaggtctt tgattcacaa gataaggaag
    15121 agtttgatat tctattttcg agagttccaa ctgaggcaac tacagatgtc aaggttcacg
    15181 ctgaaaagat ggaaacattc ttctcacaat ttcaattcaa tgaaaaagct cgaatgctgt
    15241 ctgtagtctt gcacgacaat ctggatggcg agtatctgtt tgtaggccac gttggggtct
    15301 tagtacctgc tgatgacggt ttcttatttg tagagaaatt gactttcgaa gagccctacc
    15361 aagcgattaa atttgctagt aaggaagatt gctacaagta tttaggcacc aagtatgcgg
    15421 attatacagg cgagggactg gctaagcctt ttatcatgga taatgataag tgggttaaac
    15481 tttaatagtg ttatgatatg acagtaatct taggattttt atttctattt ttgatgagtt
    15541 ggtgggttat ttcaatcgtt aatagccaga aaccacgcaa aaatgaaaca tttattggct
    15601 atatccaaag atacgatatt gatgggaatg gctatcaatc attaccgtgt cctcagaact
    15661 gagaggagtt cttgaaatcg taaaactact ttgaacaaga gttacttcaa cccattggct
    15721 ccgacggatt aagttgcttt cgtgaacacc aaaatcagcc gcaatttctt cataagtgcg
    15781 gtattctcgc acatattgaa gagtggccat aagaaggtct tctaggctta atttaggttt
    15841 tcgtccccct tttgtgtgtt taagttgata agcagttttt aatacagcta acatctcttc
    15901 aaaagtggtg cgctgaacac caacaagaca tttaaatcgt gcatcagtta gttgcttact
    15961 tgcttcataa ttcatagaac tactatacca tattttgttt cgcaggaagt ctaatgctaa
    16021 aatcttatca gtgagaagat ttcttaaagt ttattctttg tagtttcatc tgtattagta
    16081 cataatttaa cttagagaaa ataggaggat taatcgaatg gaattaaaag attttacaga
    16141 aaaagaacag gaaatgatta agaaaaggct tacaatgtct aatattagtg acaaagaaac
    16201 tactgagaag attctggcgc tagtaccaca agacttgatt aagcgaatcc cgttttttgt
    16261 cagaaaacat gctacaacac gtacgattaa acgcatttca attgaacacc ctgaactcta
    16321 cgctgtagct caaacaagtg gtgagattcc agaaaaaaaa acgcgaagaa ttgcgtcaga
    16381 ttatcacaac tatctttgaa caaaagatga ataagcatag tattaagtag agaatgaaaa
    16441 aatattttat tggcggtttg ggaagcaatg cctatcatag caaggatttt ctttaagaac
    16501 tagattcgca ggtctatttt ctaaatccat atgaaaagca tcttcgagat gaaacagaat
    16561 tgaaatcatg gtttaaaaat gagattgtag aggaagaatc tatctgtctg ataggtcatt
    16621 ctattggagg cgatttagct cgttatttcg catcggaatt tgaagaagta aaga
//
LOCUS       DAVKBK010000035        15767 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVKBK010000035 DAVKBK010000000
VERSION     DAVKBK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15767
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.035"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(19..2565)
                     /locus_tag="VWX69_001337"
     CDS             complement(19..2565)
                     /locus_tag="VWX69_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU9192671.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(2688..3128)
                     /locus_tag="VWX69_001338"
     CDS             complement(2688..3128)
                     /locus_tag="VWX69_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU9192672.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(3103..3972)
                     /locus_tag="VWX69_001339"
     CDS             complement(3103..3972)
                     /locus_tag="VWX69_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU9192673.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(4014..4742)
                     /locus_tag="VWX69_001340"
     CDS             complement(4014..4742)
                     /locus_tag="VWX69_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192674.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(4750..5229)
                     /locus_tag="VWX69_001341"
     CDS             complement(4750..5229)
                     /locus_tag="VWX69_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9192675.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(5240..5938)
                     /locus_tag="VWX69_001342"
     CDS             complement(5240..5938)
                     /locus_tag="VWX69_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU9192676.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEARI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(5931..6197)
                     /locus_tag="VWX69_001343"
     CDS             complement(5931..6197)
                     /locus_tag="VWX69_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU9192677.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(6263..7189)
                     /locus_tag="VWX69_001344"
     CDS             complement(6263..7189)
                     /locus_tag="VWX69_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU9192678.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(7264..8079)
                     /locus_tag="VWX69_001345"
     CDS             complement(7264..8079)
                     /locus_tag="VWX69_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192679.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGVFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(8083..8403)
                     /locus_tag="VWX69_001346"
     CDS             complement(8083..8403)
                     /locus_tag="VWX69_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9192680.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(8610..8690)
                     /locus_tag="VWX69_001347"
                     /pseudo
     CDS             complement(8610..8690)
                     /locus_tag="VWX69_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8734..10731)
                     /gene="metG"
                     /locus_tag="VWX69_001348"
     CDS             complement(8734..10731)
                     /gene="metG"
                     /locus_tag="VWX69_001348"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU9192681.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(10855..12114)
                     /locus_tag="VWX69_001349"
     CDS             complement(10855..12114)
                     /locus_tag="VWX69_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9192682.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(12116..12817)
                     /locus_tag="VWX69_001350"
     CDS             complement(12116..12817)
                     /locus_tag="VWX69_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192683.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(12801..14000)
                     /locus_tag="VWX69_001351"
     CDS             complement(12801..14000)
                     /locus_tag="VWX69_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU9192684.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            14265..15611
                     /gene="gor"
                     /locus_tag="VWX69_001352"
     CDS             14265..15611
                     /gene="gor"
                     /locus_tag="VWX69_001352"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU9192685.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         4678 a         3544 c         2820 g         4725 t
ORIGIN      
        1 tttttatttt aggcttattt atgcatttcc gtattgaaga acaactgctt cgactgcagc
       61 tttttcacgg ctaatcaagt caacacgtgc tgcaatttcc ttgattccca taccgatgtt
      121 acggctaaga gcaaggtcag aaagttgcgg ctcaaagaac tccttgtatt ccgccaagcg
      181 ttgctgagtc ttaaatacat gagcaggaag gataacaaag ctatcaaagc tcatatctcc
      241 tccaagggct gccttaatcc aagcccagtt ttcacgcgcc caagaccaag ctgttttctg
      301 agttgcttga tgagctagga attggtaata ccaagcagac aagtcctgtg gtttgaccac
      361 aaatttgtcc ttccaagaag taatcaagtt ttggatatta tccgcatctg tactgtatgc
      421 aagagctgct gccaactggc gtttaaagac agcatctgtt gcgtgagtat aagtatcaag
      481 ataaagtgct aacaagtctt tagtctcatg atgtttcatc tcattaatca gaacttgtga
      541 acgaatagct gctgggagtt ctgcaagatt ctccttgtgt gttgcgaaga tttggctagc
      601 gacttgacga gcttctgcat catttgagcg aatcatcatc gaaacagcca gctgacgaac
      661 caattcatcc tcatctgatt ctccgtcttt agcttcaaaa ccaagacggt catagttatg
      721 acgagccaat ttagcaacca gtcctttgaa ggctgtttca gcatccgttc cttcatcaat
      781 aaagcgctca agggctgaaa tcacttgaga aacagctgaa accaccagat aagactcttc
      841 cttagcaagt ttatcaagaa ctggaagcaa gtctgcataa gaaatgtgcc ctgcctcagc
      901 caacaaacga cgttcttgaa caatttgcag tttgcttgtg ttatcaagtg tctctagctc
      961 agcaagaaca gcttctaaca agtctccttg atagtcggta atatagtggg cagtattttc
     1021 agtgttgaga cgaagagctc cttcattttc agcaagaaga gctgcgtagc cagggatttc
     1081 gatactttca gtttcgagtg tatcaggcaa gcctttccag ttgctattga ggggcaccac
     1141 ccagagacgg ttcttgtctt cgttctcacc gatgaagaat tgtttttgtg aaatcttcaa
     1201 gacatcattt tcaactttga cagtaagaac tgggtaacca ggctgttcca accaagaatc
     1261 catgaaggct gcgacatcac gtcctgacgc ttgaccaagg gcatcccaaa ggtcactacc
     1321 aatggtgttg ctgtattggt gtttttcaaa gtaggcatgc aaacctttag caaaatcagc
     1381 atctcctagc caacggcgaa gcatgtgcat gagacggctt cctttggcat agacgatagc
     1441 gccgtcaaag agtgtattga tttcatctgg atgtttaact tcgacgtgga cagactgaac
     1501 gccatcagta gcgtcacgtt caagagcaag aggtactcca cctgtttgga aatcttcaaa
     1561 gatattccag cttggttcga tggtatccac acagacgtat tccatcatat tagcgaaact
     1621 ttcattgagc caaaggtcat cccaccattt catagtcacg aggttcccaa accattggtg
     1681 agccaattca tgggccacaa caagggcaac ttgttgacgg ctagcaaatg tagagttctc
     1741 atcgacaacc aagtaaactt cacggtaggt cacaagaccc cagttttcca tagcaccagc
     1801 tgagaagtca ggaagggcga tgtggagaga ttgaggaatt ggatacttaa ctccatagta
     1861 atcttcgtaa aactcgatag agcgaacagc gatatccagt gagaaatcaa gatttgaaag
     1921 tggatgtgct ttggttgagt agacacctac cagggtacca tttttagttt tagcggtcac
     1981 cccttgcaaa tcaccagcaa caaaggccaa caagtaagaa gacatgcgag gtgttgtctc
     2041 aaacttccag atacctgttt ccttacggtt ttcaacatcg atttctggca tgtttgacaa
     2101 ggccaattca ccttctgctt ggtcaaagcg aagagagagg tcaaaagttg ctttggcttc
     2161 aggctcatcc acacatggga aagcttcgcg cgcaaaatgg ctctcgaact gagtagacaa
     2221 gacctccttc ttgactccat caactgtata ataagaaggg taaatccctg tcatgttgtc
     2281 tgtaatttta ccagaaaagg caagaaccaa ttcaacttga ccagcctcag ccaattcgat
     2341 atgaagggct tcattgtcat ggtcaactgt aaatggacga gcttgacctg caacttctac
     2401 agaggtgatt tccaagtctt tttggtggag ggagatgcgg tcactctgtg cttgaccagt
     2461 gatggtcact ttcccagaaa aagtcttggt ctcacgactc aaatctaaaa ataaatcata
     2521 atgttcagga acaaattgct taataaaatg ttcaactgct tgcatagttt tctcctattc
     2581 taagtttaag agctgctgct cttcttcaaa caaacttatt atatcatatt ttgcttgaaa
     2641 aaaaaggatt ggacagcgat ttccaaaact ttcttccttc taatagtcta cagtgggtag
     2701 accttgcgaa attcttctaa aacaaccttg ctttcaggtg taaaagtcag ccctacttca
     2761 cccaaacagt ctgtgaaaaa gtcctcatga acctggcgcc aataggcaag tgatttgtct
     2821 ccctcacctt ccttaaaggc atgttgcgca gaaacttgat tgaagagttc aacagaaacc
     2881 tttgtaattt cgacaatgca gacagactga ttttgactat ctaaaatgat atcgaaggtc
     2941 cctacttggg gaagtggttc gtcttctagt acatagaggt cataggctga tgctgttgct
     3001 gtcttttctc ctttaaacac caaatccgct aaaagatctg gttcaactcc aaaagcccaa
     3061 gcatcgattt catctccgat caaaggattg atttgcttgt atttattcca catttcttgc
     3121 ggtatcatgg gtactccttt gtaatttttt actttcttct tttatgtgtt taagatgatc
     3181 tggatggtca atctctaaat caaaaatctc tggaatagaa ctgtagtgga taatgcactt
     3241 gatacccaac tgattcattt tttgtatgaa agaagtattc agatagcctg ctacagcaaa
     3301 atcaatcttg ttctttcttg ctttatcctg catatctctt agcatatcta acattattgg
     3361 actttccata tcatgccatt gactgtttct catagtcgca aaaacaaagg aagtcaaatc
     3421 attcattcca actacaatct ttgaaatgcc cgtttccagt atactagata agtcaaaata
     3481 cgctgacggt aattcaatca tcgttccgac tttcccagta aaaccctgct gacgcaatac
     3541 tgtaatagct tgttttaatt ggtcggcatc attgacaaaa ggaaagataa gagatagatt
     3601 gggattggtt tgataaactt ctgtaacgac atgtgcttca gcctgaaatt catccaaaca
     3661 cgccagtaaa cgcctggttc ctctatagcc aaacaaggga tgcccttcgt caaaaaactc
     3721 tctagtcccc actaaacaat tggcttctgt attcgttaat tcagaaaaac gataccaaac
     3781 ttcttcatct gagtacaggg agcagatagt ctctagataa tcttttacaa attgctgaca
     3841 acttgctaat atgatgtttt gattaagctc tctcaacaaa tattccccac gaatcatgcc
     3901 gacgtggtga aatagttgag gataaatttt ttcaagaatt ttttcgccac taagggcaag
     3961 ttgatttctc atagccattc acctcgtctt aaaagataca atatcatata taattatatc
     4021 aaaatttcct ctagttcaaa agcttcataa ggttcagata actcatatcc taaaaattct
     4081 gctacttttt tggaagcctc attatgagca tcccaaagtg gaaacatatc tctatttaaa
     4141 ctctctagaa tcattgcagc accaagcttt ttagcaaatc catttccttg ttcgtttggt
     4201 ctagttgcaa cttccacttc aactgcttta cggtaaacta accctgagga aatcccagca
     4261 atcagttcat tatttttaag aatcacaaag ccaaatccac cttttaaaac aaaatcctga
     4321 taggactcaa aatccccctg taaatcctgt gaccattctt ccgtagaaaa gcagttataa
     4381 atatgattat caataggcac aatattgtaa ccttcctcta aatgagtaac tagattattt
     4441 aaaaattcaa cttgaaaatt tgccttatct ttaaaagaat agcgagtaaa agaatttagc
     4501 cccacttttc gatgcagaaa atcttgccaa ttagtatttt ctgaaataat aatcttataa
     4561 tctaaaccat attttctaac aaaatcttcc caaaatctgg aatccaactc ccctgctagg
     4621 tatagaaaat tcccaacatc ataaaagctt gttgtcctat cattgtttcg gtagacagtt
     4681 ccaatttgag atttaagacc atagagaacc atatttttct tccatgtttt aaatagttcc
     4741 attatccctc tacttcacct tccaattcat gtaagaagtc ttgtccagtt ctggcaatcc
     4801 taataattca gacttaacct tcaagactaa tggcgatgca ttttcttctg taatctcttg
     4861 aatatccatc caaatatatc caagtgaatc attcgcacca tcagacacag cttccgaaat
     4921 cgtaacttga ggtgcactct cattcatttc aacatcatac aaggctatga catggtgaac
     4981 cataaaattt tttaactctt ccctgacgaa aacatcgtag attcgaggat tagagtagct
     5041 tctaacagta aatcccgtct cttccataac ttctctagtc agcgtttccg tcagtccttc
     5101 accaagttgc tgactgcctc caggtagatc ataccgatgt tgataagggc ctctcgtttt
     5161 ttcaatgcaa agtaactttc cattttcaaa gcaaacacag tagaccccaa agtgattttt
     5221 gatttccatc caactcctcc tacttcaaag accagccacc atctattgtc agaatttgtc
     5281 cctgcatggc agatgccttt ccactggcca aaaagagact gacttctgcc acttcctctg
     5341 gttcaatcca gcgcttgatt ggggtttcac tagccaccca gtcagctaag ccacctgtct
     5401 caaaatccgc agcggtcata gctgtcttga ctgctcctgg agcgatacca aagacctgaa
     5461 tcctagcttc agcatagtct agagccaact gcttggtgaa gccagccaag gcatgcttgg
     5521 atgaagtata ggcgtgacca cctccacctg ctaggctaga agcaatggaa cacatattga
     5581 tgatgattcc ctttttattt tccagcattt gtgtcaaata ataccgagtc aactctactg
     5641 gaataatgta gttgatttca aaaatctctt gaatgtcctg cgccgtttgt tccaacagtg
     5701 gtttgtaagc atccaaaact ccggcagtat tacacaaaac atccacctga gggcaccagt
     5761 caaaaatagg ttccaagtcc aaggtcaaat ctctctgtaa aaagtgaaaa tcaccctcta
     5821 agagtggctt ttcaccttgg tcaactccat aaacttgata gcccttctct aaaaagaggc
     5881 gagcttgagc caatccgatc cctgaactca ctcctgtaat gagtacacgt ttagtcatgc
     5941 acttctaccc aatccgttgc caaaacatca caaactgtcg ggctccacat ggaaaaacct
     6001 tctccttctc cagaaacgtt gattaggaaa taaggtgtca tttcaagtgc aagcccattt
     6061 tgctcgatgg tatcaaagag ttggacatag ttttccgcac ctccccaacc agttcgtaca
     6121 tattttctct tagcctttaa cccaggcagg atctcttcaa atgtcatgtt tttctccttt
     6181 aattctacat tcttcattta attatagcaa aaaaccactt tatacggctt tttgactgtg
     6241 agttattcaa acctgctact acttacggca aattattccc tgcagcaaga taaatttcat
     6301 accattcttt tcttgttaag ctaaagtttg ccgctcggct aacttctctc aagtgcttag
     6361 gatttgttgt acctacgact gcctgcattt ttgctggata acgcaatatc caagaaatgg
     6421 caatagttga agaggttact ccatatttaa tagctaaacg atcaagtact tgatttaaag
     6481 cttgaaattt ctcatttcca acaaagttcc ctttaaaata cccgaattgc aagacagacc
     6541 atgcttgaat gaccacatcg tgtaattggc aatattcaaa aatgctgcca tctcgcatag
     6601 ctgcttgact atcttccata ttaacatgaa aagctgattc aaatcctgga gtaaaagccg
     6661 cactcaattg tagctgatta acagctaacg gctgcttgac atctttttta agcaactcca
     6721 tcatcatagg attttgatta gaaactccaa aatctcgaac tttaccttgt ttataaagga
     6781 gatcaaaggc ttctgctact tggtcagatt ccatcaaagc atctggtcga tgaaggagca
     6841 agctatctag atgatcaatc ttcaatcttt gcaaaatacc gtctactgat tttataatat
     6901 agtccttaga aaaatcaaaa taggtaaatt cttcaatgcg aatgccacat ttggactgaa
     6961 tccacatctt ttctcttaaa tctggacgat tttttaggac aagacctaac agttcttcac
     7021 aacgaccacg accataaata tcagccaagt cgaaggcatt gattccaaca gaaagtgctg
     7081 tttctacaag ctcttcaact tcttttacag atttatcttt tattctcatc attccgagaa
     7141 caatttctga taattctttg tcatcttgac caagagttat gtatctcatc aaatttttct
     7201 cctttaattt ctaacattct tcccttcatt ataacaaaaa accgctttgc aacggctttt
     7261 tgactatact tcactccatt ttatcttctt aaacccacgg aacaagacaa agattccaat
     7321 aaagaggaca gctaaaggaa taacttttgt aaggaaaaca tttgaaattc ccatccactc
     7381 ataataacgg agcagagaac ccaccacaag atgggcaata atcatactga caaatggacg
     7441 aaagaccgct tctttccaat tccaaatacc gataactagc gaaatcgtaa agacagacaa
     7501 actatcccag ggagccggaa tataaaagac tccttcttgt atgaagcttg ccattcctac
     7561 atatcctaaa acaactagaa gaactatagt cccaacaaca atgtaagtgc caattttcat
     7621 tttaggagaa tcttggacta aacttcttcg taaaattgtg gccacaagtc caaatccaat
     7681 cagaaaaata agaagttgcc ctaaaaatgt gagcaaattg actgttaata gaggaccttt
     7741 agaaaaatca cttagtagtt gataataacg taataccgcc aggacaagaa ttggcgtcaa
     7801 aagggactct ttgatagaac tgcgaggtgc tcccttgaga atctctttca ttattttttt
     7861 aggattctta cctagataat cctctgcact catgccatct cgttctgctt ctgagaaatc
     7921 tagcatcatc aaatagatct gctctctgag atagtcttca tcatagagaa atccagcaag
     7981 attaaaactt tcccacaact cctcaaaata cttttgattc tcctcagaaa actcatgtag
     8041 caaagcgctt gtttcttcgt aatacttcat tttcttcatg gtttaacccc cattcttaat
     8101 cccttctact ttttgactca aatcgtccca ttgttgccaa aagactgaga cacgctcttc
     8161 tccttctttc attaatgaaa aatacttccg atctggacca tctggcgacg ggcgcatgtc
     8221 gcctcttatc cattgatttt tttctaactt ttgcaacaaa ggataaatag ttcctggaac
     8281 gatagtatca aatccagcct ctcgcaaagt ctgaaccaac tcataaccat accgctcttt
     8341 ttgaccaatc atatccaaga cacaaccttc aagaacacct tttaatagct gagtttcttt
     8401 catcactttt cccttctaat ctattttgta atacctacta gtaacttcac ctatagtata
     8461 tcacttctac actagtttgt aaagcataat agttaatact cttcgaaaat ctcttcaaac
     8521 cacgtcagcg tcgccctacc ttatgtatgg ttactgactt cgtcagtttc atctacaacc
     8581 tcaaaactgt gttttgagct gacttcgtca gtttcatcta caacctcaaa actgtgtttt
     8641 gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta taaataaaaa
     8701 aacagaacta gcctgaacta gtcctgtcta cttttaccca atcacacttc catttggtac
     8761 agctggatca actgtgagaa gggttaattt gccatcatgt tcagctgaga gaatcatacc
     8821 ctggctgaca tattttttca tcattttacg tggtttgagg ttagcaatga tttgaacttt
     8881 cttgccgacc aattcttgtt catttggata gtattttgca attcctgaaa gaatctgacg
     8941 atcttctcca tcaccagcat ccaagcggaa ttgaagcaac ttatctgaac cttctacttt
     9001 agacacttct ttgacttctg cgacacggat ttcaaccttg tcaaagtctt caaacttgat
     9061 ttcatccttg tttagtttga gctcaacttc gtccggattc cattcttttt cgactgctgg
     9121 tttattgcct tccatttgtt ccttgatata ggcgatttct tcttccatat ttagacgtgg
     9181 aaagataggt gttcctttgg caactacagt cacatctgct gggaagtcag ccaaactcaa
     9241 gttttcaaga ctagaaactt cttccaaacc aagttgagtc aaaactgcac gactagtttc
     9301 catcataaat ggttcaatca agtgagcaac tacacgaatg ctggctgcca agtggctcat
     9361 gacacttgcc aattggtcac gaagagcttc atccttggcc aagacccatg gtgcagtctc
     9421 atcgatgtat ttattggtac gagagatcag agtccagact gcttcaagcg cacgtggata
     9481 gtcaactgct tccatgtgtg tatggaagtc tgcgattgat tgttctgcaa cctcagcaag
     9541 aacatgatca aattcagtca caccttctac ataggcaggg atttgtccat caaagtactt
     9601 attaatcatg gaaaccgtac ggttaaggag gttcccaagg tcattagcca attcatagtt
     9661 gatacggccg acatagtctt caggagtaaa ggttccgtct gaaccaactg gaaggttacg
     9721 catgaggtag taacgaagtg gatctagtcc ataacgctct accaacattt cagggtaaac
     9781 gacattccct tttgacttag acatttttcc gtctttcatg acaaaccaac catgggcaat
     9841 caaacgatca ggtaatttaa catccaacat cataagaagg attggccagt agatagagtg
     9901 gaagcgaagg atatcttttc ctaccatatg gaagactgtt ccattccaga acttgtcaaa
     9961 gttaccatgt tcgtcttgag cgtagccaag agctgtcgca tagttaagaa gggcatcaat
    10021 ccaaacgtag acaacgtgtt ttggatttga tgggacaggc actccccatg taaaggttgt
    10081 acgagatacc gccaaatctt ccaaacctgg ctcgatgaag ttgcgtagca tttcattaag
    10141 gcgaccatct ggcgtgataa attcaggatg agctttgaaa aattcgacca aacggtcttg
    10201 gtatttgcta aggcgaagga agtatgattc ttcagaaacc cattcaacct catgacctga
    10261 tggagcaata ccaccagtca catttccagc ttcatcacgg aaaacttctg ccagctggct
    10321 ttctgtaaag aattcttcgt ctgatactga ataccaacca gagtattcac ccaagtagat
    10381 atcatcttga gcaagtaagc gttcaaagac ttgtgcgaca actttttcat ggtagtcatc
    10441 agttgtacgg ataaatttat cgtatgagat atctagtaat tgccagagtt ctttaactcc
    10501 aaccgccatt ccatcaacat aggcttgagg tgtaatacca gcttcttccg ctttctgctg
    10561 gattttctga ccatgttcat caagacctgt cagataaaat acatcgtagc ccatcaggcg
    10621 tttgtaacgt gctaggacat cacatgcgat agttgtgtag gcagaaccga tatgaagttt
    10681 cccagatgga tagtaaatcg gcgttgtaat ataaaaattt ttttcagaca taatttttcc
    10741 tttccaggca aatgaaacct gtttttctaa cacttcatta tatcacattt ttaatgaatt
    10801 tcgataggga aatccataca aaaacaagat agacgagtgt ccatcttgtt gatctcattc
    10861 ataacgaagg gcttcaattg gatcaagttt cgatgccttg ttggctggca agactccaaa
    10921 aatcatacca acactagccg aaactgcaag actaaatagg gcaactggga ttgatactcc
    10981 aacttctata ccttctatta aaccttgcag taacaaacct gctaaggcag ttaaaccact
    11041 tgcaattgtc aagccaatta agccacctaa caaggtcaaa atcatggatt caatcaaaaa
    11101 ctgaattaaa atattggcac gtgttgcgcc caaagcctta cgaagaccaa tctcacgagt
    11161 gcgctctgtc accgaaacca gcatgatgtt catgacacca gttcctccaa caaagagaga
    11221 aatccctgcg atggaactaa taatcgtcgt cataaaacta aacgattgtt gaatttctgc
    11281 aaatacaacg gactcatctg ccacctggta ttctccctgt tgtaagcctg caagctctgt
    11341 catttttcgt gccagttctg gacccagagt tggggttaaa ctggtatcat tcactcgaaa
    11401 gacaatacta gctatttcat ctatattaaa attcgcagca agggagatat tggtagtaat
    11461 aggcaagcca ccaaacccat atatttttga ccttttagcc tccggactag tataaacccc
    11521 aatgacccgg taactaaatc cattgacttc tacaaccttg ttaatagcct cttgaggaga
    11581 ttcaaataaa ctaatggaca attcctcatc tagcaaaata acacttgcaa actctttgaa
    11641 atcttgctct ctcagactac gacctgcaat aatttcattc ttaacagcgt ccatgtaagt
    11701 tctgtttcca cctgtcaaat tagcattctc aaccttttta tcttgatagg tcaagatggc
    11761 attcgttgaa ttggttacat agtaactatc cactcccttc agtttagctg cctcttggac
    11821 ccaggattct tgcggttttg gcggttcaac aggaatttcc tcttcctttc cagaaaccgt
    11881 aaaagatgat tgtttctgag taaaagaacc atctttactt tttttaggag agaaaaagac
    11941 gctaatattt ttctgagatt tagtcatatc tttattgact tgacgagata gggaatcacc
    12001 caaagccata atcacaacaa ctgatgaaac accgataata atcccaatca tagtaagcaa
    12061 agaacgcatc ttgtgagcca tgatagatga aaaggcaaat ttcagattct gcatcttagt
    12121 tttcctcctt tcctaactga gcactgtcag acgaaatgac cccatcccga atgacaatct
    12181 gacgtttagc ataggcagca atctcaggct catgcgttac catgataatg gtttttcctt
    12241 ctttattcaa atcaaccaat aattgcataa tttggttacc tgttttggta tccaaggctc
    12301 ctgtcggttc atccgctagg ataatagaag gattgtttac caaggcacgc gcaatggcta
    12361 cacgttgctt ttgaccacca gataattctg aaggtaaatg gtgactacgt tctgtcaatt
    12421 caaccttgtc taaatattcc tcagccaact tgcgacgttt tgaagacgaa actcctgcgt
    12481 aaatcaaggg caattctaca ttttgcagag cattgagctt cgatagaaga aagaactgct
    12541 gaaagacaaa accgatttgt tggttacgga ccttagccag ttgtttttca ccaagcccag
    12601 ccacttcttg accttcaaga taatattctc cactggttgg tgtatccaac atgccaatcg
    12661 tattcatcag agtggactta ccagacccag atggtcccat gatggctaca aattcaccct
    12721 cattcacttc tagattgata tttttgagaa cctgcagttc ttggtcacca ttacggtagc
    12781 ttctgaagat attttttaga ctaattagtt gcttcatcag ccttcacctc ttttccttct
    12841 tccaaggaag atgttggatt actgatgacc ttagcaccat tcgttaaacc agaagtgatt
    12901 tcttgatttt ctgcgtcagc atttcccaat gaaacctcaa cttttttagc cttttgttgt
    12961 tcatccacaa tccagacata atttttacta tcatccatta ctagactgct aacaggaaca
    13021 agaatagcct tagttttgct tttaacctca atgttgacag aaaaaccctg tttcaaatca
    13081 ccaacctcgc ctgtcacatc aatagtataa gggtatttag aacctgtatt attcccggct
    13141 gctggactag ctgcttcacc attgttttta ggatagtcag aaatatagct taatttccca
    13201 gtccattttt tatcaggata cactttagaa gtaaagctta cttcttgacc tacagaaagg
    13261 ttggctagat tgtactcaga caattctccc ttgacttgta aattttcatt gctgacaata
    13321 tgaaccataa cttggctcgc ccctgttgga gatttagaaa cattgctatt gacttcgact
    13381 acagttccct ctagggtact gagaacagtt gttgcatcca attgactttg agccttgctt
    13441 aattgcgctg cagcatctgc acgcgcatca cgggcatcac ccaattgagc gtcaatagaa
    13501 gcaacagaat ttccagccac tggagttggg ctttgcaccg ttgcatcttc tcctcctact
    13561 ggcgctggta actgtggagc cggagctgaa gcggcttcat ttcgtgcttg attgagttca
    13621 ttgatatgac gatctgcctt agctactgct cgactagctg aatcataggc cgcctgcgct
    13681 tctgaactac tgtacttgac taaagcctgc ccttcgctga ccttatcgcc cacagaaaca
    13741 aggatttcat ctaaatcacc cttactagca tcaaaataaa catattgttc attttttgct
    13801 gttactgtcc ctgacaataa aacagaggag gccacgcttc cttccttggc aacaacaaga
    13861 tgagtaggct catcttttag agcagtctga gaaggttgtc taaagagtaa aatcccccca
    13921 gcacccaata caactacact cgcagcaccg attgctgcat acagttgcca ctttttagct
    13981 ttaccattct ttttcttcat aatgaaactc cttttctttt ttacaatact ttgctattat
    14041 accaaatttc cctccagcaa acaatacagt tcaggattaa acaatcgttc ggaattttgc
    14101 ttttctattg tactagatat ataatacact atcttgactt atttggcaag cttttttgca
    14161 attttttgtg cgtagcagat ttttgcaatc aaatcaaaaa aagaataaaa tataactatc
    14221 aaaaaagacg ctctactatt taaaagatta caaaggagtt ttcaatgaga gaatatgata
    14281 tcattgctat cggtggaggt agcggaggaa tcgctaccat gaaccgtgct ggtgaacatg
    14341 gagccaaagc agccgttatt gaggaaaaga aattaggtgg aacctgtgtc aacgtcggtt
    14401 gtgttcctaa aaaaatcatg tggtacgggg cgcaaatcgc tgagactttc catcaatttg
    14461 gagaagacta cggctttaag actactgatc ttaactttga ctttgcaacc ctacgtcgca
    14521 atcgtgaagc ctacattgat cgcgctcgtt cttcttatga tggtagtttt aaacgcaacg
    14581 gtgtagactt gattgaaggt catgctgaat ttgtagattc tcatactgta agcgtaaatg
    14641 gtgaactgat tcgtgctaaa catatcgtga ttgctacagg tgcccatcca agtattccta
    14701 atattcctgg tgctgagcta ggtggctctt ctgatgatgt atttgcctgg gaagaacttc
    14761 cagagtcaat tgccattcta ggcgctggtt atatcgccgt tgaattagct ggcgtactcc
    14821 acacttttgg tgtcaagaca gatctctttg ttcgccgcga tcgtccttta cgtggttttg
    14881 attcctacat cgttgaaggt ttggtcaagg aaatggaaag aacaaactta ccacttcaca
    14941 ctcacaaagt ccctgtcaag ttagaaaaaa ctactgacgg cattaccatt catttcgaag
    15001 atggtactag tcacacagct agccaagtta tctgggctac aggtcgccgt ccaaacgtta
    15061 agggcttgca acttgaaaaa gctggagtga ctctgaacga acgtggcttt atccaagtgg
    15121 atgaatacca aaatactgtt gttgagggaa tctatgctct aggtgatgta acgggcgaga
    15181 aagaactgac tccagttgca atcaaggccg gacgtaccct atctgaacgt ctctttaacg
    15241 gaaaaactac tgcaaaaatg gattactcaa ctattccaac tgttgtcttt tcacaccctg
    15301 ctatcggaac tgttggtttg acagaagagc aagctattaa agaatacggt caagaccaaa
    15361 tcaaggttta taaatcaagc tttgcatcta tgtactctgc ttgcactcgc aaccgtcaag
    15421 aatcccgttt caaactcata acagctggtt cagaagaaaa agttgtcgga cttcatggaa
    15481 ttggctacgg cgttgatgaa atgattcaag gatttgccgt tgctatcaaa atgggagcaa
    15541 ccaaggctga ctttgatgca actgtggcaa ttcacccaac tgcatctgaa gaatttgtaa
    15601 ccatgcgtta atcgaaacaa aagaagcaaa gcaaaaaaca cttctaaata tcaaaaagcg
    15661 agtatttccg tagttggaga tactcgtttt cttatgtttt attttatagt atgttgaagt
    15721 aagatatgca aaaatcaatt aacaaaccat agcaaaatac aaggatt
//
LOCUS       DAVKBK010000036        15635 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVKBK010000036 DAVKBK010000000
VERSION     DAVKBK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.036"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            111..275
                     /locus_tag="VWX69_001353"
     CDS             111..275
                     /locus_tag="VWX69_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9192686.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            359..925
                     /gene="amaP"
                     /locus_tag="VWX69_001354"
     CDS             359..925
                     /gene="amaP"
                     /locus_tag="VWX69_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU9192687.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            937..1107
                     /locus_tag="VWX69_001355"
     CDS             937..1107
                     /locus_tag="VWX69_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU9192688.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1146..1754
                     /locus_tag="VWX69_001356"
     CDS             1146..1754
                     /locus_tag="VWX69_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9192689.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1785..1988
                     /locus_tag="VWX69_001357"
     CDS             1785..1988
                     /locus_tag="VWX69_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9192690.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2098..2376)
                     /locus_tag="VWX69_001358"
                     /pseudo
     CDS             complement(2098..2376)
                     /locus_tag="VWX69_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3140..3910)
                     /locus_tag="VWX69_001359"
     CDS             complement(3140..3910)
                     /locus_tag="VWX69_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU9192691.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3925..4773)
                     /locus_tag="VWX69_001360"
     CDS             complement(3925..4773)
                     /locus_tag="VWX69_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU9192692.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDNFEDPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTGLDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4770..6245)
                     /locus_tag="VWX69_001361"
     CDS             complement(4770..6245)
                     /locus_tag="VWX69_001361"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU9192693.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVNFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6568..7923)
                     /locus_tag="VWX69_001362"
     CDS             complement(6568..7923)
                     /locus_tag="VWX69_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9192694.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLNQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWHAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7933..8250)
                     /locus_tag="VWX69_001363"
     CDS             complement(7933..8250)
                     /locus_tag="VWX69_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9192695.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8267..8584)
                     /locus_tag="VWX69_001364"
     CDS             complement(8267..8584)
                     /locus_tag="VWX69_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9192696.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8599..9495)
                     /locus_tag="VWX69_001365"
     CDS             complement(8599..9495)
                     /locus_tag="VWX69_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU9192697.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9498..10760)
                     /locus_tag="VWX69_001366"
     CDS             complement(9498..10760)
                     /locus_tag="VWX69_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9192698.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11040..12218
                     /locus_tag="VWX69_001367"
     CDS             11040..12218
                     /locus_tag="VWX69_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9192699.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLISQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12446..12892)
                     /locus_tag="VWX69_001368"
     CDS             complement(12446..12892)
                     /locus_tag="VWX69_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192700.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSILKLE"
     gene            12962..13621
                     /locus_tag="VWX69_001369"
     CDS             12962..13621
                     /locus_tag="VWX69_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU9192701.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWKLLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTCHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(13673..14824)
                     /locus_tag="VWX69_001370"
     CDS             complement(13673..14824)
                     /locus_tag="VWX69_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU9192702.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(14839..15570)
                     /locus_tag="VWX69_001371"
     CDS             complement(14839..15570)
                     /locus_tag="VWX69_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192703.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
BASE COUNT         5207 a         3120 c         2384 g         4924 t
ORIGIN      
        1 ttgatttttt gatattaaaa taaaaaagga gggtaggcag tgttgtgatc aattattgct
       61 ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa aagtagttct atgggaatca
      121 tcgcaaatgt attcgctggt ttagtcgggg catatgcagg acaatctctt ttaggtagtt
      181 ggggtccatc aatcgctgga atggctttgc tcccatctat tgtaggtgca gcgattgtga
      241 ttactgtagt gtcattcttt acaggtagaa agtaaacttt tcgccagtaa agttagcaaa
      301 ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt aaatcgaaag gattgtatat
      361 gtcaaaagca aagaaaatat gtttcattat tttctgtatt ttaatcttga caattttcct
      421 tcctgttttg atagattatc atcaagttag tgatctaggt attcatctac ttagctggag
      481 acagaactcc gtagttgaat tctatcttgc tagatatgtc ttttggggga cagtggttct
      541 atcaacttta gttttattat ccattttagt tgtgatgttt tatcctaaac gttacttgga
      601 aatccaactt gaaactaaaa acgatacatt aaaattaaag aattcggcaa tcgaaggttt
      661 tgttagaagt ttggtgagtg atcatagatt gatcaagaac ccaactgttc atgtaaattt
      721 acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt cttccttcag acaacatcgc
      781 tgacagatgc caaataattc aaaatgaaat aactaatgga ttgaagcagt tttttggtat
      841 tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac caaccaaaac ctcaaaacaa
      901 aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg aatggcttaa acaatatcga
      961 tatccaatta tcgctggtct cataggcgta tttctggctt gtttgattgt ctcctttggc
     1021 ttcttcaaaa caatatttgt attgatttta ggagcactgg gagttgcagc tggattatat
     1081 atcgaaaaaa actatataga taaataaaaa aataaaaatt actaatttaa ttaaaggagt
     1141 ttcatatgtc aaacgaaaaa aacacaaaca ctaacgtaga aaagaaagat gctactgttg
     1201 tagctcacga aatcaaaggg gaacttactt acgaagataa agttatccaa aaaatcattg
     1261 gtctttcact agaaaacgtt tcaggtcttt tgggaatcga tggtggtttc ttctcaaatc
     1321 ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg tgttaacgta gaagttggta
     1381 aaacacaagt tgcagttgac ttaaacgtta ttgttgagta ccaaaaaaat gttccagctt
     1441 tatattcaga aatcagagaa atcgtatctt cagaagttgc taaaatgact gacttggaaa
     1501 ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa agaacagcat gaagcagact
     1561 cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc aacaggagaa ttcacttcag
     1621 aacaattcga aaaagctaaa tctggtcttg gatctggttt ctcaactgtt caagaaaaag
     1681 ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg tgtagtatct cacgaaaaca
     1741 ctcgtgtaaa ctaagataaa ataaatataa caggagaaat tatcatgtca gtagaagaaa
     1801 aattaaatca agctaaaggt tctattaaag aaggtgttgg gaaagccatc ggtgatgaaa
     1861 aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa agtaaaagaa gtcgccgaag
     1921 atgccaaaga cgctgtagaa ggtgctgtag aaggtgttaa aaacatgttg agtggcgacg
     1981 ataaataagg ttaaaagtta ctttatcttt ttagtaacat tagtcaaaag agtctgagtc
     2041 aagatgattc tcagaaaaca aaaagctaga gattcccaat tgcggaactc tagcttttta
     2101 attttgcctc tttctcttat tatatttcag caggttgttg gccatgagta tgaatcccat
     2161 gtcaattctc acttgacgct tacctctcag atgacatctc ttataaccca aacaaacctt
     2221 tatctgccca aagacagatt tcatatcaat cttacgttta gcgaaaattt gtctaccctt
     2281 ggaagataaa agtgcctgat attctttagt ttttaaacac tggtaacgtt cattcatata
     2341 cagtcccttt tgaggggctg attcaggttc ataatcgcag tcaacattga tttcaaggct
     2401 gtttgctttc tatctcccct ttttcatgat atattttcgt acaggtgctt caatagtttc
     2461 tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata atgttcttgt ggcatattca
     2521 ttagattttc gtaaaaagtt ctctcctatt tgtgagcgaa caggtatagt caattgattg
     2581 tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc agaatccatc caagggtggc
     2641 tggcacaatt tctagtgaac ctctttaaat ctattacgtt tgactgtgga aaagagtttt
     2701 caaaatggaa agatatttcc aatcatcacg atagtgagag cttttttgcg aatctaggat
     2761 gtccaagata gcggtgtctc aacgaacatt caaatagact tttaaggtgt catgacttgc
     2821 caaagcagac agatttcaac gaagtcagtc aagaatttta ggctgggcaa gaactcaatt
     2881 tcaggagaaa atgaaataaa tattcccaca ataaaacgca tagtatcaaa gtttttccaa
     2941 cacctgatat tatgcatttt ttaattttaa agactttttc ccagcctcaa gaaatcacat
     3001 cccacctaaa tcctttggat accaaatacc tcatcaggtt attttctgag ttggtaagac
     3061 tgtctagctt aatttgacaa atggagggcg ttaaatccag tttttacagg aagtctattt
     3121 aaatattttc acactgacct tacaaaatat gaaataaatt atataaagtc attcccatga
     3181 caaagaataa catcccttta aaacagtatc ttacccaatt ttcaggtaag acttttgata
     3241 caaccgtccc caatacccct ccgcatatag aagcaagaaa aataactgga acaggtgcta
     3301 aatgatactg atttaaacct gtaaccacaa caattgtagc caaatgagac agctgggaaa
     3361 agaaaataat tgcaagagaa tacatcgttg cttcttttat cgaaatagaa aaaaacacca
     3421 tcaataaaga tacattgagc ggacctccac caatccctaa aaaactagaa atcaagccca
     3481 atagaagacc acaaatcata tagaatccta tcttatcaaa ttgataagtt tttttaaaat
     3541 ctgttaaaac aaatgataca agtagcatca caaatagtaa aatcatttga acaatggata
     3601 ctagccgtac tgataattga gataacaaaa cttgaaaaat aagatgacct agaaatcctc
     3661 ctaaaacaga agaaaaggat accgtaaaaa tcaatctcca ttttatctct ttactttgtg
     3721 aaaatctttt ggttgttgaa ataatcgcca ttataaaaac agagaaacta gaataaaaag
     3781 caatatcact gaccgaatgg tatccaaaac tatccataag tggcttaatt ataattccac
     3841 cacccatgcc tgatatagaa cccaatccac tagctattat aatgattaga aaataaataa
     3901 tctcaaccac tttttaagtc catcctattc tttcaaacat ctaaaaccta gatggctact
     3961 agtggaagta gaaatacatc catttctagc agctactcgg tatcgattac aataagaaca
     4021 atgacataaa aaggaacctc ctctgatagc atactcctca tcttgtatcc catattttgg
     4081 caactcatag tcatcttcat taaaactagc taataaggta tatctcggat tgcgacacca
     4141 ttcccaaaca ttcccaatca tttgatatag accaaaatca ttaggtaaaa attcatagac
     4201 aggagccgtt cctataaatc catctaagcc agtattttca taaggaaatc ttccttgcca
     4261 agtattggca tgataatatc caccttctaa aagagtatct ccccaaggat attcagattg
     4321 tcttcctcct ctagcagcgt attcccactg tgcttcagtc ggtaaagaca ttccgctcca
     4381 attacagaaa gccaatgcat cttctaaagc aacatgaact actggatggt cttctaaacc
     4441 cactagatta ctgttctcac cgtagggatg tttccagcaa gcgttcggaa cttgtaacca
     4501 ccacggagcc ccggcaggat gaggatatcc ctccctttct gcctccggaa cgaacaatat
     4561 aaaaacaaaa gaccactctt gtcgctcagc tagtgtttta tagcctgttt ctttcacaaa
     4621 ttgagcaaat tcttgattcg taactggagt atccgcaatg gaaaaatcct ttacactaac
     4681 agcgacttga ggatcttcaa aattatctaa aaagccctct tcagaatttg ttcccatcat
     4741 aaatgtccca cccttgattt ttttcatttt catgattgac tatcccccgt tttcgttaga
     4801 gttggcgtta ttttagaaag ttcaacagga actaactctt catccacaac aaaaccttct
     4861 tctctatatc taagaaagtt tactaatttt ttcttcatct gacgaacaat aggttggtat
     4921 ttttcacttg gatacaaatc attcatttca tgcggatctt ttttcatatc aaataactga
     4981 taatgattta aaacaggaaa ccagataaat ttccactggt ctgtcaaaat atattgacta
     5041 gaatcttttc ctaaagcatg ttcaccatga aattctgttc gccacccctc gtactgtcca
     5101 aataataaat tcttaacact ccgtccatct agttcatctg tagtagttcc tcctgccaaa
     5161 tccacgagtg aaggaaaaat atcttgaatt ttcactaatt gcttgattgt tcccctatta
     5221 ccagctatca atccagccgg atcgtaaata aacgaaggaa tgtggatact tccctgataa
     5281 ggatatccct ttctaaacag ataatgttca ccaagctgat ctccatgatc cgaaacaaac
     5341 cagataatcg tatctttatc atgacgaaat tcttttaggg cagtcaaaaa gcgactaatt
     5401 tgatggtcta tatgagtaat caatccaaaa taagcagcaa ccattcttct ttgatcatct
     5461 tcctttaatt tccctcttaa agcataaata gacggaattt gcttttctaa tacttcccaa
     5521 ttcccgatat gcaaatcgag aaattgaggc aagcgttcca tatacatatc aaaatagtat
     5581 tttgggggat ttaatggagc atgtggtttt tcaaaagaca ttttgagaaa aaaaggaacc
     5641 gttggatctc ttctttgtaa aaatgaaatg gactcactca caacccagtt tgttggatgt
     5701 aacttttcat ctttatccca aggtctagct tcccaagaat tacaatccat tccgtcatca
     5761 atcaaatcaa catcataacc aactttaccc tttaaaaagg ctagatagtc actagcataa
     5821 tcaaattgac ttccataagc cttatcatac tttctatcaa catgtagata cccatcgtga
     5881 agtaagacat gatcaaaccc aagtctctgt ctggaaggaa aaacatgcat cttaccaata
     5941 cactctgttt gataacccat atctttaaag acttttggaa gagtattagt aaaattccaa
     6001 ggcacctcat cttgataacc aacacgtcca cttttatctt ggtctaagcc agtcaataaa
     6061 gctgccctag caggaacgca agaaggaact ggagaatagg cattttcaaa attataacct
     6121 acactagcca tcatatctaa tgttggagtg ctaactagct tatccttact attcaaggat
     6181 aaggcgtctg ctctcatttg atctacaaca atcaaaataa tatttggctg ttttgtctga
     6241 accataaaat ctcctttcta atatggcaaa agaggcacaa gaagatatct acctttactg
     6301 cacccctttc tatatcaatc tctctatata aaacaataac attcttgtta tgttttatat
     6361 aaaaatgaac taaaatatga ctaaatcgat taggaaattc aaatcatttt ctagtactgt
     6421 tttagaagtt acagtgtact attccaactt caataaacta taaacctttg tctattaaca
     6481 attttagtgg agataagaaa tcctacacct aactcatctt acacgtaatc tatttctatt
     6541 ttatcacaaa aaacgcaagt aagaccatta actcaattca gttttatctg ccattttcac
     6601 aaatgggaaa taagtcaaga cactaataat caaacaaaca actgataaga tgatggcatg
     6661 ccaatcaaat gctgtagaga agaaaccata taaaattgga ggcattaccc aagtaacatt
     6721 ttgtgtaaca ggtgaaacaa gaccccagct tgttgcccag taagctaccg ttgccatgaa
     6781 aaccgggcta agtacaaatg gtataaatag caaaggattc aagacaactg gtaaaccata
     6841 attgaccggc tcaccaatat taaacagaac tggtgctaga ccaagtttag caacttttcg
     6901 ataatgactg tttcttgaaa aaattaaaat agcaagtact aatcctaatc ctccaaacca
     6961 gacaaacgcc ccaaaagacc cacttgtcca tatataagga atcggttcac ctttttggaa
     7021 agcatccaga ttcgctaaca tagcaactcc aaatagccct tccatgatgg gagccaatac
     7081 atttcctcca tggagaccaa aaaaccagaa taacttattc aaaaagatca tcagaataac
     7141 tgcaaagaaa ctttgagaca aacctagtaa tggcgtttgt aacaccttgt aaacccaatc
     7201 aatcaataag tcattgctaa gtaaatggaa aacataagtc aagatggcta ctatatacat
     7261 cgccataaat cctggaatga tagaagtgaa cggcttagca atcgcagggg gaactgaatc
     7321 tggtaacttg attacccagt tctttttcat tactttacag aaaataatag aggctaaaaa
     7381 tccaatcatc atggctgtaa agtatcctct ggcattaata tggtttcctg gaatcacatt
     7441 cccaatagtt accatcagat ttttaccatc aaatgctaga ttatcaattc cttgtaagat
     7501 ttgatttaat ttcacatctc ctacatttgc caaagggaaa ctctttgtaa ctgtacttcc
     7561 aatcgaaatg acaaacgaag caagtgatac caaaccagca gaaactgtat caaccttgta
     7621 aatcttagcg atattcactc ccaagcaata gatgaacaat aaggaaacaa ttggtatact
     7681 tcccttgaat accaaattat tgatgtcaac aagccactga aaggttttcg taatactttc
     7741 taggtgaaat tgttgtggta aatccactag aaaagcattt aataacaaag caatggaacc
     7801 tgtcataata acaggcatag tccccacaaa tgaatcacgt aaagcaacta aaaacttctg
     7861 attcccaact ttcattgcaa ttggagaaag tttttcttgc attttatcca acattgtatt
     7921 catagcaaat tcctaatttt tttcaaatcg ttcgtatact tctaccactt ctttcgccaa
     7981 gtcaacaaag gtcagactcg tcattaaatg atcttgcgcg tgtaccatca agaggctaat
     8041 tgaagtttct tccccctgtg cctctcttgt caacatttct gtttgagcct tatgcgcctg
     8101 taataaggca gcattcgcat cagctaatct tcgattggct ttagagaaat cccctttttt
     8161 tgctgcctga atagcctcca tagcattact tttggcttcc ccaccataca taattagccc
     8221 cattgcagat tctaaattac tttcattcat agcattctcc tcaatcttag tctaataaac
     8281 tttcagctaa atctaagact ttagaaccat tcatcattcc ataatctgtc atcggaataa
     8341 ccgccacagg aatctgtcta tcttttagtt tttcttgaaa gtcccctagt aaatagcgaa
     8401 cttgagggcc taaaagcaac acatttactt cctttgttgc tacaatttct tctgcttcag
     8461 gagctggaac tgcaaaaatt tctgcatcca accccttatc ttctgctgcc ttttgcatct
     8521 ttgtcactag cagacttgta ctcatacctg ctgcacatgc taacataatt gttactttag
     8581 ccatagctta ctcctttatc acctatttac tgacctagcc aagcgagata ctgtatgtct
     8641 cactcctcta attgccttgc tcaatgcata aatattatcg actgttgcca gtcccccata
     8701 tcctgcgtca cctatatgtt gaatatcaac tccacaaatt ttatttctaa gtgcaatttc
     8761 cttgatagta tctgtatcag atgtttcttg gctagtacca atagcactca gtactagccc
     8821 acccttacta tgaacgagat caacgacttc acgcaactct tggtcatgaa aggctggaac
     8881 ggttccaact gctggaacaa gtatcacatc cgcacctgct tccaacaatt gctctgctac
     8941 agaaagctct gccacaggct cattcactcc tgccccgtgc atcttacctg caataatcaa
     9001 accagaaaag ttttccttag cagtttgaac agccttaatg atttctcgat tgctaactcc
     9061 tgttccagga tttccagtca aacagacaaa gtcaaaacct aactcctcta ttcgattcaa
     9121 tgtttcaaca ctagcaacac gacctgcaac aatttcctgt gtttcctcta gcatctttgc
     9181 agatgggtca atcggttcca aatttacacc aattggacaa gcaacaagct ggtgtaagcg
     9241 atgaataaca tcatcacctg aactatccaa agcataaatt ttaggctcaa aaacatcaac
     9301 acaattcaat aaaatcatat cagctccaaa agctctagca atttcagaat tagttatatc
     9361 cccaacaaat gtctcacgag taactacatt ttcagataga acaactctac cttcacttgc
     9421 taaaatactt tgttttaatt cttcagcatt catctgtaat atctcagatg gatttgcact
     9481 aattaaacgt ttcattctca atcctccaat aacttaaacc gtttttcaat agctattaca
     9541 aatggtaaat aaagtaagac atccaaaaca atcaatacaa tttgtaataa tgaaccagaa
     9601 atacttcctg tagcaagtaa accacttata acaggtggca tagtccaacc tggatctgta
     9661 taagttagcg gaaccaaacc tgatgccatt gctccccacg ctactagtaa gttaaacatt
     9721 ggagctaaga taaatggaac tagtaacaaa atgttcaaaa caataggaac gccaaacatt
     9781 gctggttcat ttatattaaa taatccaggt ataacagtta taggtgccaa agtttttagt
     9841 tgtttactag ctttcttctt atgtgctaaa tatcctaacg caagaactaa acctatggtt
     9901 gcaccaccgc cacctatgaa tacaaaatta tccataaata cgctagtaaa aatatttgga
     9961 agagtttctc cagtttgata agctacttta tttgcatcta gattagctaa ccataacggt
    10021 ttcataactg cattaacaac atttcctccg tgtaatccta caaaccaaaa actactatta
    10081 aggaaaatta agataagaag accaataaca ttatttccta aaagtccaag tggacctccc
    10141 aaagctactt gagcaatttc atgaagatta ggtaaactta atttatctaa agttgcataa
    10201 acaatcaacc aaccaacaat agtcactgca ccaggaataa tggcactaaa gcttttagat
    10261 actgctggtg gaacaccatc cggcattttt atctgtatat tatgatttat aaaccattgg
    10321 tagatatagc cattaatcaa tcctaaaatc atagcaacaa ataaaccttt tgatgccatg
    10381 aaagcggtag gcattcctgc tccagcctct cctctaatga aaggcgtaac tgtaataaaa
    10441 gatgataatg acacaatacc agcaggaata ccatcaactt tgtattgtct agccataaag
    10501 taagcgatac caaaactagc tacaagacca agtaatccaa aactactatc aacacccttc
    10561 cataaatagt cagcaacacc aatatcaccc agatattttt cccatcctgg aataggaaaa
    10621 cttgcaataa ccattagtaa tgaacctatc aacaataaag gtatagttag agtaataccg
    10681 tctcgaatag aaaccaacgc tttattatta cccaatctag ccgctactgg aagtaacttt
    10741 tcttgtaata atttttccat aaccttttcc tcttaaatat attttattat caaaagttat
    10801 caattatctt tattttttga cgtcaagttg ttatttgatt atcttttgtt atttatattt
    10861 tacaactata agaaagcctt gtcaaggatt tgtgtaaata tttgattatt ttttattatc
    10921 aatatataat aaaaagagac cagtaagcaa tgaaaagctt aaaaagatta acatctacat
    10981 ttatccatag caaaaaatca taggatttta agaatctgac aactaggaag aaaactaata
    11041 tgaccttatc taagaaacaa ttacaactac gagctaaaat actggaaaca gtttacacat
    11101 taggtcccat ttcacgaatt gaaatcgcta ctaaaacagg aataacacct gcaacaacta
    11161 gcagtatcac aaatgatctg attaaagaaa acattctctt agaacttggt gaagacgaac
    11221 acgatacaag cgtagggaga aaaaaaatcc tgctagacat tcaagctaaa cgattttact
    11281 acattggttg tgaactatct gaaaaacatt tcacttttgc tttaggagat aatctaggaa
    11341 atatcttaaa ggaagagaaa gaaattgtta ctaaacagtt aatccaagaa aagggaaatc
    11401 aactcattag ccagacacta aagcaattct taaataactg ctctgattat gaaatagaag
    11461 caattggaat cgcgctacct ggtcgctatt tagatgatta taaaataaca acaaacaatc
    11521 ctttatggca acatatcgac ttagaaatga ttcaatccca ctttgataag cctttgtttt
    11581 tctctaacaa tgttaactgt atggctatag gtaaacgcct atttagtcgc caacagaatg
    11641 accctaattt tgcttatttt cattttgcta gaggtatgca ctgttcttat atctacgacg
    11701 gaaacattta tggaaaagga aatctaatga ttggagaaat agggcataca gttgtttcat
    11761 ctgagggaga agaatgtagt tgcgggcgca agggatgctt acaaactttt gctggagaat
    11821 cttggttaat caaaaaatca aaaattctat atcatcaatc tccctattct ctacttccta
    11881 gtttagtcaa aaatgccgat gatattgata tccaagttat tttaaccgct tatcaattag
    11941 gtgacactgg aataatcaca cttatccatc aagccttact ctatcttagt caaaccattt
    12001 taaatatcag tatgatgatt gactctcaaa aaatctacct acatagtcct ttactaacaa
    12061 atcaacacat catccaaaaa ctatatagtg aaatgaacta caaacccaaa ctgctctata
    12121 atcgcctacc tgaagtcatt attgaacctt acaatgattt tacagccgca cactcagcta
    12181 ttgcactttg tttgtatcat acaattctac attcctaatt ttctattaca tttaataaat
    12241 aggctaaaaa gagggagtat atcataaaaa gcgaacaaac ctgttttctg aaaatcagaa
    12301 ttctgttttg ttcgctttct ttatatttgg aattatactc ctatctcccc tttttcataa
    12361 tgtatagtaa aatgaaataa taacaggacg aatcgatcgg gacagtcaaa tcgatttcta
    12421 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tatactatat tttcgtacag
    12481 gtgcttcaac catttgaacg atttcaaatc cttctttttg gtaaagattc tgagctcttt
    12541 gatttgcctc gaagacattt agagaaatac tatctatatc ttcattttca aaggccaaac
    12601 taacaaattt ccttaaagcc tggctaccta agccttgctc ctgtttctgg gggttgataa
    12661 aaaatctccc gatatgaaga ttgctgtctt ctagcctgat tttctggata aatcccacaa
    12721 actcttgttc atcaaagatt gaaaagactc cttccaaggc ttgaagggtc agtagaaaag
    12781 gaatccttgg tcccatccat tgttcttgaa aggatttgcc tagggagttg gaccactggc
    12841 atacaaattg agcgttttct atactcacct tttcttcaaa acgaattgtc atcttttcct
    12901 caccatctta tctatgtttc tccattatac tatttctccc attttttacg aatagataag
    12961 tatgattgat ttttattttt ttctcgtcgg gagcattctc gcttcctttc ttggtttggt
    13021 cattgaccgt tttccagagc aatccattat cagttcagcc agtcactgcg attcctgtca
    13081 gactcgcttg cgtcccttag atttgattcc gattctctca caggtcttca atcgctttcg
    13141 ctgtcgctac tgcaaagttc gctatcctgt ctggtatgcc ctctttgaat tagtcttagg
    13201 actcctcttt ctgctttact cttggaaatt gctttccttg gggcaagtcg tcctaatcac
    13261 cgctggtttg accttgggta tctacgactt tcaccatcag gaatatccct tactggtctg
    13321 gatgacttgc cacctaatcc taatagcttc ctctggctgg aatctggtca tggtctcctt
    13381 cctcatactt ggaattttgg ctcattttat cgatatccgc atgggtgcag gggatttcct
    13441 ttttttagct tcttgtgctc tcgtctttag cgtaacggag ttactgatct tgattcagtt
    13501 cgcttctgcg acgggtatcc tggcctttct cctgcaaaag aaaaaggaaa gacttccttt
    13561 cgtgcctttc ctcttacttg ctacttgttt gattattttt ggtaagctac tgcttgtcta
    13621 ataaaatcca atttctgcca tatgtccttc atgaaattat ttcacagtta aattataaat
    13681 tatttctttt gtacaaaggg atgatgttat caaatcgatc tgttcttcta tcttcttgat
    13741 actgatcaaa aaatttcatt tcgactgaaa atatttcgct tataaactgt aaacgaatac
    13801 tttgtttaga cattatagtc gctagactga ctagatgatt actcaaaacg acgtccagaa
    13861 tactctttac tttgcttggt tttttaacaa aaatttgatc atccaaaggt tcaatcattt
    13921 tgtaaccttt ttgcgcaatt tgacgataaa agtaagaatg ttgctttgga gtcaataatc
    13981 ctaacttaaa agctcgatac tctaaagcct gtatcgaaac attcaaatcc gacttcaata
    14041 aaatataact atcaggattg ctgacacgct tgccaaccct ctcttcaaat ttgactaaaa
    14101 actcttcttt tggcaataaa aaacatgatg caaaataatt tgcttcttgc tccaaacgat
    14161 cgccatcttc attcatatct ttatatttat gtaaaagaat atgtcctagc tcatgagcta
    14221 agtcaaaatt tcgacgtaca gatgatttat tcgttcccaa cacaatataa ggtcttccca
    14281 attttgacca tgcgctataa gcatcagctt ggccattaat taatcgttcc acgatataga
    14341 tgcctgaacg ttctaattta taaagcaaat catgattatc ttttgaaata cctaattttt
    14401 ccctggcata aagagccaat tcctcaatgg attctccctt atgataagat tcactcacta
    14461 cattacttag gtcatgaatt gtaatattag gtataattac aaaactttca aaataatcaa
    14521 tcaaactatc taccttatgt aaatacatag tttgaatatc tattgttttc cgtgttgcta
    14581 ggtctgcatt tctaaaggca attacagaag aatcaaatcg aatgctctct tcttcctgtt
    14641 caaaataagt taaatcaaca tgaaattggt tggccaaatg cattttggtt gataatttag
    14701 gtttcgtttc gttggactca aactgccaaa tggcttgttc cgttaaatta attctctgag
    14761 ctaattctgc tctacttaaa ccatttaaca gccgtaattc tttcaatacc cgaccattaa
    14821 acatttacat actccttact acttttgacc ttcttgtttt tctattcttg gaataatttc
    14881 aaaatcttct gtttccgata attctgaaaa attaggaata tcttggtatt tagcttcttc
    14941 gaaatggtac gaacttgatt gaatatactc agacaaatct tgaatcaagt gtaactgacc
    15001 agttcgtgca tcaggcataa caacatctac agatataata ttgttttctg agtccgcctc
    15061 ataagttaaa atcataaatt tttcgatatt cgaatttttg gtagcttgtt caatttcttg
    15121 aatcatttca tcagaaacta actccatctg aattggaaag gaatgactat cttcatcatt
    15181 tttgtaggaa gaatgttgat taagataaag tgtattcatt tgagcatatt caaataagta
    15241 gccactctta tttttttgta ccaaaggaaa ttggttcgta agtcgcttct taccctttat
    15301 aattaacaat actttcccat atttttctgt atttgtttca aattctaaat atccccaagt
    15361 ctgtcctgct aattgtaatt tatactcaaa caaatctgct gatgcaaatg cagtatcaat
    15421 atgattaggt cgcgtccatg cataaccatt cgacactatc attgtctctc ttttttctag
    15481 acgttcatct acataatctt tttgcccttt catcaaagta tctacaattt tttgtgcctc
    15541 aagcgaatca aagagatcct gattcaacat aattcttcct cctccaaata ctttttaatg
    15601 aattatatca ttttcttaaa gaaattacta caata
//
LOCUS       DAVKBK010000037        15338 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVKBK010000037 DAVKBK010000000
VERSION     DAVKBK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15338
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.037"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..955)
                     /locus_tag="VWX69_001372"
     CDS             complement(<1..955)
                     /locus_tag="VWX69_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192704.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEP"
     gene            complement(965..1918)
                     /locus_tag="VWX69_001373"
     CDS             complement(965..1918)
                     /locus_tag="VWX69_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9192705.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMSDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            complement(1911..3117)
                     /locus_tag="VWX69_001374"
                     /pseudo
     CDS             complement(1911..3117)
                     /locus_tag="VWX69_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            3360..3653
                     /locus_tag="VWX69_001375"
                     /pseudo
     CDS             3360..3653
                     /locus_tag="VWX69_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3760..4111
                     /locus_tag="VWX69_001376"
                     /pseudo
     CDS             3760..4111
                     /locus_tag="VWX69_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4387..5693
                     /locus_tag="VWX69_001377"
                     /pseudo
     CDS             4387..5693
                     /locus_tag="VWX69_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5733..6743)
                     /gene="tsaD"
                     /locus_tag="VWX69_001378"
     CDS             complement(5733..6743)
                     /gene="tsaD"
                     /locus_tag="VWX69_001378"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU9192706.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(6733..7170)
                     /gene="rimI"
                     /locus_tag="VWX69_001379"
     CDS             complement(6733..7170)
                     /gene="rimI"
                     /locus_tag="VWX69_001379"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU9192707.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYVLAYDGAEVIGFLAVQENIFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(7167..7850)
                     /gene="tsaB"
                     /locus_tag="VWX69_001380"
     CDS             complement(7167..7850)
                     /gene="tsaB"
                     /locus_tag="VWX69_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU9192708.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8028..8213
                     /gene="cibA"
                     /locus_tag="VWX69_001381"
     CDS             8028..8213
                     /gene="cibA"
                     /locus_tag="VWX69_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU9192709.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8215..8367
                     /gene="cibB"
                     /locus_tag="VWX69_001382"
     CDS             8215..8367
                     /gene="cibB"
                     /locus_tag="VWX69_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU9192710.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(8690..8905)
                     /locus_tag="VWX69_001383"
     CDS             complement(8690..8905)
                     /locus_tag="VWX69_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192711.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            9185..9418
                     /locus_tag="VWX69_001384"
     CDS             9185..9418
                     /locus_tag="VWX69_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU9192712.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            9420..11099
                     /locus_tag="VWX69_001385"
     CDS             9420..11099
                     /locus_tag="VWX69_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9192713.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            11153..11245
                     /locus_tag="VWX69_001386"
                     /pseudo
     CDS             11153..11245
                     /locus_tag="VWX69_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11452..13365)
                     /gene="mnmG"
                     /locus_tag="VWX69_001387"
     CDS             complement(11452..13365)
                     /gene="mnmG"
                     /locus_tag="VWX69_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU9192714.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(13375..13830)
                     /locus_tag="VWX69_001388"
     CDS             complement(13375..13830)
                     /locus_tag="VWX69_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9192715.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQYGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(13971..15092)
                     /gene="mnmA"
                     /locus_tag="VWX69_001389"
     CDS             complement(13971..15092)
                     /gene="mnmA"
                     /locus_tag="VWX69_001389"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU9192716.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
BASE COUNT         4536 a         3433 c         2801 g         4568 t
ORIGIN      
        1 ttggttcgat atcattcatt ttatttgact caattggatt aattgaatac aattttaaaa
       61 aaataggctt cgtaccaata atagaggata attgacctcc taattcacct agcgctgtaa
      121 aaataacacc tgttagtgct cctattgctt caatagtacc aattttcact attcctttta
      181 ttgcaagata gcctgttaaa aaaacgagag atatctgaaa aaaaatattg agaaagaagc
      241 taatagcgcc tgctaacgtt tctacagttg tctttctttg tataaccatc tttaataaaa
      301 ttcctgcttc tttaattttc ttaggcaata catataaaag attcaaggat gctaacacat
      361 caaatccatt caatatagtc tcactagatt ttaaaaaagc ttcattttgg ttagttaaat
      421 ttagactaac ttctcgcatt ttcgatgcaa agatttttgg tacaagtagc ataatcatta
      481 atgaaaacaa ggtggctaca gtcaatgacc aatgatagtg attaagagtc acaactgcaa
      541 atatagtacc agaaattcct tttattacta aaaaaagttg tttaaaagcc tgatcattta
      601 aagtctgaac atcattattt agccacgaaa gatatgttcc tgatgattta ctatgaaatt
      661 cttgataggt agagttagag atgtctgtgg caactctatt tcgaatctct agattaaact
      721 cttggatcac ttcaacctga taatttttca ctacccagtc aaggaatatt atcccacacc
      781 agacaatcat ttggtagatt gacaatttca aaaaccgctc taaattcatc gcaattaatt
      841 cattcaacac cagagcatta atagttgctg cataaattag caataattga ccagcaacaa
      901 taaatatcgt taataaacta aattttttta tatttgattt tataatagta tacacaatag
      961 tttctcactt tctaaatttt aattgaacat agttgtcata tatacaatag aaaaaaccaa
     1021 aatgatataa taacatatat ttcaaaaaaa gaaattcgtt aaaaattttt tcttctcttg
     1081 ccttcttgat tacttttaaa gccttgcatt tgtctcctat taatagtaac cgctttatgt
     1141 ttaaagaata atatttcttt gtaaccaata ttctctcgtt gaaactcaat aaattaaaat
     1201 atttcctaca gtaattataa tattcttcat ctgcattaat tgttttttgt gtcactccag
     1261 tgataccgtt ttctttactg tgagcgtagt aattcaccaa gaattctcgc actatatcaa
     1321 tttggtatcc ttgagcaagt agttttaata aaacaacacc gtcctgatgt gaatctattt
     1381 tctcaaaacc attaattaat tctagcacct cttttttaca caaccaaaat gacgtacctg
     1441 ctatattgtg aaccatttga acaaacaagg gatttccaac aaaatcggtc ttctcctctt
     1501 ctcgtgtacc atttggataa attattattc cataactata aactaaagct aaattcttca
     1561 ttctactctt tttaaaacaa gccatcaact ttaaaattcg atctgacata tattcatcat
     1621 catcgtctaa aaatgatata tacttacctc tagaattttt gatacctatg tttctggcat
     1681 tagttgcacc taaatcttca ttacttaaaa ttaacttaat tctatgattg gtatagccaa
     1741 attgatggat aattttattt cttaaattta cattactata attatcatca ataattataa
     1801 cttcgatatt tttataactt tgatgtaaac aacttttcac agctctaatc agagattcat
     1861 acctattatg tgttggtatt ataatactta ctaattcttg atctatattc ctatccatga
     1921 ctactcttct ctaataattc atcatatact ctcatggttt ctacaaacat tttttgcaca
     1981 gaaaaatgtt ttcttatttt tgatttacta ttctcaccta tatatttcaa atactcagaa
     2041 tcattgagta aaaaattagc acaagcacac actccctcaa catcttcctt ctcaaataaa
     2101 aatccatcaa ccctatgttc aataatttca cttaacccgc caacattact agctaaaacc
     2161 ggagttcctt gtgacattga ctctaaaaca cacataggta ttccttctgt atcagaagga
     2221 atatacaata aatccgatat ttggtaaact atagtagctg gatagatttc accaagtaac
     2281 ctgaaattat ctctacattt caaatggcaa attttttctt tcaaagcagc ccacatacta
     2341 ccatttccag ccataataaa aatcacatct tctctgacta aaaataattt ttctgcaaat
     2401 tcaaggaatc tatccggcct tttttctgga tccaaccttc caacataaca aatgattttt
     2461 ttgttatttg gaatacaaaa ttctttttta aagtcttgaa cacctactac atctaaatcg
     2521 ctatttgata cattaattcc gttatttatt acaactatct tcttattttt ttattatact
     2581 ctccaatctt tttttcatag tttcagatac acaaataaaa gcatctccca tagaatatgt
     2641 ccaaaaatca aaataagtca agaatttctt ttttaagtta tattcaaccc atccatggca
     2701 tgttatcact gtcttaacct ttccaaatcc attcttgtca agttttttta acatatataa
     2761 aaaataatta gttgagtagc catgacagtg tataagttgg atttttaata attttaaaat
     2821 atttttaacg tgtaaggcag tttcaaaatt atttgaacat tgagtacaat caacataggc
     2881 aatatctaaa tttttataat catcaataac ctttgaatct ctagatacga ttatcaaaat
     2941 aggatataga gacatccttc tgatctgctt tttacaaagt ccaattatat gcggatctat
     3001 acctccacaa tgtccattat tatacctaac tataatatga gccgaaaaca ctatatcctt
     3061 aatgtctcca tatccatcag ggatattaat atttattttt ccacaactat attgcattgt
     3121 aaccatctcc ttaaacgacg cattatgata tttgatagag aaatttttat gaataactca
     3181 ataattttat agtaaatcat gcttatatct caaagatacc tattttctct tgtctcgacc
     3241 ttctccaaag aattgctata atactattac aaatacatct gcactacact tcaaatttta
     3301 gcactgtata aaaacgtttc aacacactaa ctttaagaaa acttccacta ttaattgaaa
     3361 aagttgatag agataaatta aagatctata ttgaaactca tcccgatgct tatttgactg
     3421 aaatagctgc tgaattcaac tgtcctccaa caactattca ttacgctcta aaggctatgg
     3481 gatatagtct aaaaaagagc tgtacctact gcgaacaaga cccagaaaaa gtaaatcggt
     3541 tccttaaaga attgaatcac ttaagctacc tgactcctat ttatatttat gagacagggg
     3601 ttgagaccta tttttatctc gaatatgatc gagccttgag caggcagtta gtctctctgg
     3661 aagaagatat aattatttga attaagatcg agacaacgca caccagagat tgcgatactg
     3721 ttatagaagt actaatgccc ttttttgttt caatatacta tggctccgat gacctataaa
     3781 gatacgatga cgagtgactt tttcgaagct tgcttccaaa aattcttact acctacttta
     3841 gatacaccat cccttatcat tatggacaat gcaaggtttc acagaatgaa catgtgtaag
     3901 gagcagggca tagactgtta ccacttccta cctattcacc cgagtataat cccattgaga
     3961 aaatatgggc ttacatcaaa aacatctcag aataatattg tcaaattacg atgcttttct
     4021 tgaggcactt ttgtcctatt cttgtttcag ccgactatac tccgttattg ggcagctacg
     4081 gaacagtcga tgggacgatg gggggacata aaaaaatcct ccagttttgt tttttataac
     4141 agtatactgg agaattgaca atctcggtag atacctcgtt atagcgcggt tacttattag
     4201 gcagttacaa aacaactgtg aacagaaaac attccagagt cagacaagac tttggaatgt
     4261 tttggctcta taatttctgt agtgggtaat cccaccccag gaattatagg gtcgtttctt
     4321 gtagaaaaaa agccccatat gacctataat gaaaagcgtc taaccaactc attagaaagg
     4381 gttcatatgg aacaacttaa gaataccaca gatttgctcg gattgaaaga caaaaatatc
     4441 aaaatcttgt ctgttctgaa ataccaaacc catctagtcg ttcaggcaaa gttggattcc
     4501 cccgctcctc cttgtcctca ttgtcaaggg aagatgatca aatacgactt ccagaaagcc
     4561 tctaaaattc cgcttctcga ctgtcagggt ttacccacgg tactacatct caaaaagcgc
     4621 cgctttcagt gcaagaattg ccttaaggtg gtcgtttctc aaacatccat tgtcaagaaa
     4681 aattgccaga tttccaacat ggtgagacaa aaaatcgctc agctcctcct tgaaaagcag
     4741 tctatgactg agattgccca cagattggcg gtctcaactt ccaccgtcat ccgaaaactg
     4801 agggaattta agtttgaaac cgattggacc aagttgccaa aagttatgag ttgggatgag
     4861 tatagcttca aaaagagcaa aatgagcttc attgcccaag attttgagtc caaatccatc
     4921 ctcgcaattt tagacgggcg aactcatgcg gtgattcgaa accatttcca acgctatcag
     4981 agagaggttc gggagctggt cgaggtcatc accatggaca tgtacagccc ttattatcgg
     5041 ctcgctaagc aactctttcc aaaggcgaag attgttcttg accgcttcca cattgtccaa
     5101 catctgagcc gagctatgaa ccgagtacga atccaaatca tgaaccaatt tgaccgaaaa
     5161 tccttggagt atcgggcgct caagcgcttt tggaaccctc gctttttcgt ttctaggctc
     5221 gggctaaatc agtccactgg actgatttac tacaccagga tagcttcaag ctctgtcaga
     5281 aacgattcta tcagcccacg tttcgaatgc acttaaccca tcgggaagta cgagataagc
     5341 tgctttctta ctctgaggga ttacaggttc actacgaact ctatcaactc ctgctctttc
     5401 attttcaaga gaagaatgcc gaccatttct ttggattgat tgagcaagaa ctgccaacgg
     5461 ttcatccgct ttttcaaacg gtcttttgga cttttttaag ggatagagat aagattatca
     5521 acgcacttaa gctgccttat tccaacgcta aacttgaagc gaccaataat ttgattaagg
     5581 ttatcaagcg caaagccttt ggtttccgga actttaacaa ttttaaaaaa cggattttga
     5641 tgactttgaa catcaaaaaa gagagtacga atttcgtact ctccagattg tagcttttcg
     5701 cctacccact acacttgaca aagagccact ctttattcca tggtatcaaa ggcaagactt
     5761 ggtttggcat tgaggtccca gcctgcgaag ttttctttgt tccactcgct gacgctggca
     5821 taggcaatca tacctgcatt gtctccgcag agtcgcagag gggggatgat aaccttgaca
     5881 tctgtgattt cggctgctag gcgttctctg agacctttat tggctgccac accacctgcc
     5941 acaactaggg ttttaacagg atatttctcc aaagccttct tggtttttgc catgagaatg
     6001 tccataactg ctgcttggaa ggaagcacac aaatcttctg tagacaggct ttctcccttt
     6061 tgctcggcat tgtgatgaag attgataaag gcagatttca aacctgagaa ggagaactcc
     6121 agattatctt ccttaatcat ggcacggggg aaatcataaa tatcctgccc ctgatgagcc
     6181 agctcgtcaa tctcacgacc tgcaggatag gtcaagccca tgacacgacc gaccttgtca
     6241 taagcctccc caactgcatc gtctcgtgtc tccccaacaa tcttgtaatc tcctgcctcc
     6301 gaaacataga ccaactctgt gtgcccaccg ctaaccaaga gggctagcaa gggaaactcc
     6361 aaaggctcca cactctgagc tgccatgagg tgcccagcca tgtgattaac aggaatcagt
     6421 ggaagtccgt gagcccaagc aaaggccttg gcagctgaca aaccaactag caaggctccg
     6481 accaagcctg gtccgtaggt aaccgcaaca gctgtcacgt cctcttcggt aatccctgct
     6541 tctgccaatg cctcctcgat acaggctgta atgacctcga catggtgacg actggctact
     6601 tcgggcacta cgccaccaaa acgtttgtga ctctcaattt gactagcaat gacattggac
     6661 aagagctcat cgtcgttttt caagacggcg acactggtct catcacagga tgtctcaaat
     6721 gctaaaatat atctatcctt catctatttc tctcttcatg ataatggcgt cctcgactgg
     6781 gtcatggtag taggcctttc gctcagcgat gaccgccatt ttttctttct tgtaaaatgc
     6841 ttgcgctcgt tgatttgact ttctgacttc gaggaaaatc tccttatctg tcggcaattg
     6901 agcaaacaag gctgacgcaa ttccctgacc ctgataagct cctttaacag cgatttgcaa
     6961 gacttctgcc tcaaagatat tttcctgaac agctagaaaa ccaatcactt ctgccccatc
     7021 ataagccaga acataccaag tctggtcttg ggacaggtct gcttggattt gctccagagt
     7081 ccaaggactg actaggtaaa cagctgccat aacagcgtag atggcttgag ctaggtcagg
     7141 ctgttgttga attcgcttga tttctatcat aggcgtttaa tgtaggactc accagactcg
     7201 gtatggttct tgagccagtt ttcctcagcc tcgactcgtt tgaggtaatt cggcacaaaa
     7261 tcatgcaagg agtctgcttc cttgtcccaa gctaaaagag caagattggc tgcattgggc
     7321 aatgtttctt tgtaatcagt ccttggcaag tgtttttgaa tctgctcaac aaaggggcca
     7381 acttctccga caaaggttac ctgactagta cccttgactt tttctagcac ctcttcaaaa
     7441 gataggtgcg cttctgccat gacaggtttg gcattttcat aaaatcctgc ataaacatta
     7501 ttgcgacgcg catccatcaa ggggacaaac aaaccttctt gttggtgggg caccagagcc
     7561 aagagactcg acataccaac caactcgatg ttcagggtgt aagctaaggt cttagcagtt
     7621 gctaccgcaa ttcgcaagcc tgtatagcta cccggccctt cagctaccac gattcggtcc
     7681 aaatccttgg gtgtccaatc caaacttgcc atcaaaaaat cgatggcagg cataagagta
     7741 atactgtgat ttttcttaat attaatcgtc gtctcggcaa gaacctgctt atcctctaaa
     7801 atagccagag aaagagcctt gctggacgta tcaaaagcta atactttcat aacacattcc
     7861 tatctttttg tctgcttact attatactac aaaagctggc acatgggaat tttctttgcc
     7921 cccagacaag agtgccctca cttaactaaa aataatttaa aaaaatgctc acttttcctt
     7981 ttcttttccg aatataaaag tgaacaagaa aaaaggagga aagttcaatg acaaattttg
     8041 acattcttga caatcaattt ttatccttat ctgaaaatga attatcagat attgatggcg
     8101 gtctcgctcc cttggttatc tttggagtag cagtatcttg gaaggctatt gcaggtggaa
     8161 cagcacttat aggttctggt ttggcagctg gttatttttt aggaggagat taatatgatg
     8221 aaagatttga acaattatcg tgaaatttct aataaggaat tgcaagaaat caagggtggc
     8281 tttggtgtcg gtgttggtat cgctttattt atggcaggtt ataccattgg aaaagacctt
     8341 cgtaaaaagt ttggtaagtc atgctagata agaaacacat ttttagaagg ataaatttta
     8401 ttgtcttcat ctcttacagt ttgctcagca ttctcaatga tttgaacatt actaccatcc
     8461 ctttaccatt cgatttatct gtttgtattg ttttattttt atgcttcaac tctatttttg
     8521 atcagaacaa tgactcccat aaaaataata agctttgaaa attccattgt catgtcatgt
     8581 tagaaaaatg caaagaccac ctcatcttga tagatggggt ggaattttcg tgtcgtaaat
     8641 ctactatctc tacatcccca aacaaaaaac cccagcataa gcagggcatc taagcattta
     8701 attcaaagta aaatacaaac caaacgacat aggtcacgag gaggagaaaa agcgagtaga
     8761 gagtcacaaa ggtcattttc cacaagaact tggtttgtcg tcgttccagt ttggcaaata
     8821 gaagattccc cgcataaacg caagcaacaa aaacaataaa agctaccaag cgagctccga
     8881 tagcaaaagc aaataagtta tacatagggc aacctccttg acttaaaatc tatatggaat
     8941 tatgacaagc aataaatttc acttccgtta tcaacataat acattttctt tattcttgca
     9001 aacgcttacc aaagaaatcg tcccctaact ttctcgtttc cgtcttttac taatttttca
     9061 ttttgtggta taattgaaat aattgtaacg aatcaaggtc aatctagaca caaaatggaa
     9121 tgaaatcaag caaatatctg ctaaaagttt ggaataagct gacctgtaaa tagaaaggaa
     9181 ctatatgatt tacaaagttt tttatcaaga aacaaaagaa cgtagcccac gccgtgaaac
     9241 aacacgcgca ctttacctag acatcgatgc cagctcagaa cttgagggtc gcatcactgc
     9301 tcgccaactt gtcgaagaaa atcgcccaga gtacaatatc gaatatatcg aactcttgtc
     9361 tgacaaattg ctcgattacg aaaaagaaac tggcgccttc gaaatcacgg agttctaata
     9421 tggcctatac tcttaaacct gaagaagtcg gcgtttttgc catcggtggt ctgggagaaa
     9481 tcgggaaaaa cacttacgga attgaatacc aagacgagat tatcatcgtc gatgctggga
     9541 ttaaattccc agaagatgac ttgcttggta tcgactatgt cattcctgac tactcttaca
     9601 tcgtggacaa tatcgaccgc gtcaaggctg ttttaatcac acacggacac gaggaccaca
     9661 ttggtgggat tccgttccta ctcaagcaag caaatgtccc tatctacgct ggaccgcttg
     9721 ccttggcttt gatccgtggg aaactcgaag aacacggcct cttgcgcaac gccaaacttt
     9781 acgaaatcaa ccacaacacc gagttgacct ttaaaaatct caaggcaact ttctttagaa
     9841 cgactcactc tattccagag cctttgggga ttgtcattca tactcctcaa gggaaaatcg
     9901 tctgtacggg tgactttaag ttcgacttta ctccagttgg agaacctgcg gacttgcatc
     9961 gtatggctgc gcttggtgaa gaaggcgtgc tctgtctcct gtctgactcg acaaatgcgg
    10021 aagtaccaac ctttaccaac tctgaaaaag tcgttggtca gtccattatg aagattatcc
    10081 aaggtattga aggacgtatc atctttgcat cctttgcctc aaatatcttc cgtctccagc
    10141 aggcaacaga agctgctgtt aagactggac gcaagattgc ggtctttggt cgttctatgg
    10201 aaaaggccat tgtcaacgga atcgatcttg gctacatcaa agctcctaag ggaaccttta
    10261 tcgagccaaa tgaaatcaaa gattatcctg caggagaagt tcttatcctc tgtacaggta
    10321 gtcagggtga gcctatggca gctctctctc gtatcgccaa cggaacccac cgtcaagtac
    10381 aattacaacc aggtgatacc gttatcttct cttctagtcc catccctgga aacactacta
    10441 gcgtcaacaa gctgattaac atcatttctg aagctggtgt cgaagttatc cacggtaaag
    10501 tgaacaatat ccatacatct ggacacggtg gtcagcaaga gcaaaaactc atgctctgct
    10561 tgattaagcc aaaatacttc atgcctgtcc acggtgaata ccgcatgcaa aaagtccacg
    10621 ctggactagc agtggatact ggtgttgaga aggacaatat ctttatcatg agcaatggcg
    10681 atgtgcttgc ccttactgct gactcagctc gtatcgcagg tcatttcaac gcccaagata
    10741 tctatgtcga tggaaatcgt atcggtgaaa ttggcgcagc tgtcctcaaa gatcgtcgcg
    10801 atctatctga agacggtgtc gttctggcag tcgcaactgt tgacttcaaa tcgcagatga
    10861 ttctgtctgg tccagacatc ctcagccgag gctttgtcta catgagagag tctggcgact
    10921 tgattcgcca aagccagcgt atcctcttca atgccattcg tatcgcactg aaaaataagg
    10981 atgccagcgt gcaatctgtc aatggtgcca ttgtcaacgc tattcgcccc ttcctctatg
    11041 aaaataccga acgtgaaccg atcatcatcc cgatgatcct cacaccagat gaagaataaa
    11101 gcaagaaaac agccccgtcc tcggagctgt ttttctctat gctttctttt gagattaaaa
    11161 ctcatactca atgaaaatca aagagcaaac taggaagcta gccgtaggtt gctcaaagca
    11221 ctgctttgag gttgtagata gaactgacga agtcagtagc catacctacg gcaaggcgac
    11281 gttgacgcgg tttgaagaga ttttcgaaga gtatcaataa aaatcgaaat cagactagaa
    11341 ggctaagcga aagcataact tgagttagct cccatagttc gggaaactat gggaggctgg
    11401 agatgaatca aagccaagct ttgaactcat tcgtaagaag ccgacgacgt atcattttga
    11461 tttttgaaga gttttagaaa tactacgatt tttaccttcc agatacacca tcaaaataga
    11521 aatatctgct gggtttactc ccgaaatacg gctggcttgg ccgatggttt ctggattgat
    11581 gagtttgaac ttctgacggg cttcggttgc gatagaatca atgtcatccc agtcgatatt
    11641 ggccggaatg cgtttttctt ccatgcgttt catcttggca acctggtcca tggctttgga
    11701 aatatagcct tcatacttga tttctgtttc aatcaattcg ataatcttgt catccaagtc
    11761 ttctgcagct ggtccgatga aggccaccac atcttggtaa gaaacttctg gacggcgaag
    11821 gaattccttg gctgtcactg catcggtcaa gggtttgaag cccatctcct caaccttggc
    11881 attggtttcc ttgactggct taagtttgat actgtctagg cgcttcatct cattatcaaa
    11941 ttgatttttc ttgatttcaa aacgagccca gcgttcatcg tccacaaggc caatctcgcg
    12001 tcccatctca gtcaagcgca tatcagcatt gtcatgacga agaatgagac ggtattcagc
    12061 acgactggtc aagagacggt agggttcaat ggttcccttg gtcaccaagt cgtcgatcat
    12121 caccccgata taaccatcac tgcgcttcaa aatcaattca ggcttgcctt ggattttcag
    12181 agccgcattg atacccgcga taatcccttg gccagcagct tcttcgtaac ctgatgttcc
    12241 atttgtctga ccagcagtga agagacctga gattttcttg gtttccaaag tcgcacgcaa
    12301 ctgatgaggc aagaccatat catactcaat agcataacct gtccgcatca tctctgcatt
    12361 ttccaaacct ttgatggaat gaaccaagtc acgctggaca tcctcaggca gactggttga
    12421 aagtccttga acatagactt cctcagtatt gcgcccttct ggctcaagga agagttggtg
    12481 acgttccttg tccgcaaagc gcacaatctt gtcttcaatc gacggacagt aacgaggccc
    12541 cactcccttg accacacctg taaacatagg cgcacggtgg aggttgtttt gaataatctc
    12601 atgactggta ccattggtat aggtcaacca gcatggcact tggtccttga cataatcctc
    12661 atcacgtgaa gtgtatgaga agtgattagg cgcttcatct cctggttgga tttctgtcac
    12721 gtcgtagttg atagaagagg ccttgacgcg tggaggggtt cctgtcttga aacgaccgat
    12781 ttcgagaccc agttccttga gattgtcagc taggttaata gaagccaagc tgtggttagg
    12841 acctgatgag tacttgaggt ctccgatgat aatttcccca cggagagcag tccctgtcgt
    12901 cacaataaca gccttagcag catattcttg atgggtggct gtacgcacac cgacaacctt
    12961 gccatcttcc accaaaatct catcaatcat ggtttgacga agggtcagat tttcttggtt
    13021 ttcaaccgtc ttgcgcatct ccttagagta aagttccttg tcagcctgcg cacgaagggc
    13081 acggacagct ggccccttcc ctgtgtttag catcttcatc tggatgtaag tcttgtcaat
    13141 ggttttggcc atctcgccac cgagggcatc gacttcacgc acgacaatcc ccttggcaga
    13201 accaccgata gagggattac aaggcatgaa agccagcatt tcaatattga tggtcgcaag
    13261 caggacctta cagcccatac ggctagcggc caaggaagcc tcaaccccag cgtgtcccgc
    13321 accaattaca ataatatcgt attcttcagt aaaatgataa gtcatgtttc tctcctattc
    13381 ctcaagatga atgtgtctta gttggccttc ccaatctggt agggctgttt ttaaaaaggc
    13441 tggaactagc tggatattct ggagcttatc caagtcaatc cactcacagg gctgcctttt
    13501 ctcatcttcc tgcatggtca atggggcatc ttcaagcaaa tccaccagat aatgaaactc
    13561 gatattgtga taggaaacac cgtattgttc aaaacgattt tcaaccacaa aagctagctg
    13621 cccagcttga gctttaacac ccagttcttc cttcacttca cggactaccg cgtcttccgt
    13681 gctttcattg acttgaatcg cacctccaat agtgtaatac ttgcccttgt ctttggtaac
    13741 tagaagcttg tgattttgga caatcaaggc tgtcgcccga acaccaaaaa ccgtattgtc
    13801 tacttttgtc cgaaagtctt gttgagtcat tcttgtcctt tcccttaaac gacacaaaaa
    13861 cagtcaaaac tacaaagaag tgcaggacaa aaaagcctgc aacatccatg agctttgacc
    13921 atcatttcta ttgctgttat tattgtagca aattgagaaa atttgtcaat ctaaatgtac
    13981 tgacaaactt gtccatcgcg gtaagcattg tcaatcaaac caccacctag acactcttcg
    14041 ccatcgtaaa agacaactgc ctgtcctggt gtaatcgcgc gttgtggttc cgcaaagatg
    14101 acctctgcct tgtctccttt gacatggacg gtcaccttag agtcaggctg acggtaacgg
    14161 aatttagccg tacattctag cgtaaactct tctggcattt cacgagtaaa gtggacttga
    14221 ctggcttcta ggctagttga catgagcgaa tcatggtaga atccttgtcc tacatagaga
    14281 atattcttgc ttagatcttt tccgacaacg aaccaagggg cattgtcacc gccgtgttgc
    14341 ccaccgatac cgagtccgcc acgctgaccg attgtatagt acataagacc tgcatgctcg
    14401 cccatatcgc gaccatccac agtcatcatg cgaccaggct gagctggcag gtagttgctg
    14461 aggaagtttt taaagttctt ttctccgata aagcaaatcc ctgtcgagtc tttcttctta
    14521 gcagtcgaaa ggcctgcttc ttctgctagt tttcgaactt caggcttttc caaatgtcct
    14581 agtgggaaca tggttttttg aagttgttct tgcgaaagtt ggctgaggaa ataggtctgg
    14641 tccttgccat tgtccacgcc acgaagcatg tgaacagtgc cgtcctcatc acgcgccact
    14701 cgagcataat gcccagtcgc tacatagtct gcccccaagg ttatggcata gtccaaaaag
    14761 gccttgaact tgatttcctt gttgcacata acgtccggat ttggcgtgcg ccctgcacgg
    14821 tattccgcta ggaaatactc aaaaacgcgg tcccagtact ctttttcaaa attgacagag
    14881 tagtagggaa tgccaatctg gtctgccacc gcaaccacat ccttgtaatc ttcggtcgcc
    14941 gtacagacgc cgttttcatc tgtgtcatcc cagttcttca tgaagatacc gatcacatcg
    15001 tagccctgct ccttgagcaa aagagccgtc accgacgaat caacaccacc actcatcccc
    15061 acgacaacac gtgttttaga gttatcactc atggtaagtc tcccatctat tcgtttattc
    15121 acgattgaag gtcgtgtgtg cttcacgatt gaaggtcgct tgagcagtat tcattataac
    15181 acgcttggtt agagaagaca aggaagagct taaaaattgt tttttaaaac ttatagtcaa
    15241 tatacagatt atgtgaatga cgtgagtata ccttcttctt atcttcattc aaataactat
    15301 aataaataaa acaacccatt ttctctaatc tatttttc
//
LOCUS       DAVKBK010000038        14811 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVKBK010000038 DAVKBK010000000
VERSION     DAVKBK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.038"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(158..1788)
                     /locus_tag="VWX69_001390"
                     /pseudo
     CDS             complement(158..1788)
                     /locus_tag="VWX69_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            2081..6991
                     /locus_tag="VWX69_001391"
     CDS             2081..6991
                     /locus_tag="VWX69_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU9192717.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYRFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            7081..8277
                     /locus_tag="VWX69_001392"
     CDS             7081..8277
                     /locus_tag="VWX69_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU9192718.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     VALTEK"
     gene            8413..8940
                     /locus_tag="VWX69_001393"
     CDS             8413..8940
                     /locus_tag="VWX69_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9192719.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9017..9373
                     /gene="glnR"
                     /locus_tag="VWX69_001394"
     CDS             9017..9373
                     /gene="glnR"
                     /locus_tag="VWX69_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU9192720.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYENQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9410..10756
                     /gene="glnA"
                     /locus_tag="VWX69_001395"
     CDS             9410..10756
                     /gene="glnA"
                     /locus_tag="VWX69_001395"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU9192721.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10852..10971)
                     /locus_tag="VWX69_001396"
     CDS             complement(10852..10971)
                     /locus_tag="VWX69_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU9192722.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11516..12835
                     /locus_tag="VWX69_001397"
     CDS             11516..12835
                     /locus_tag="VWX69_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9192723.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRII
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYI
                     QRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNS
                     TGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEE
                     KASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            12892..13689
                     /gene="psrA"
                     /locus_tag="VWX69_001398"
     CDS             12892..13689
                     /gene="psrA"
                     /locus_tag="VWX69_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU9192724.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            13700..14305
                     /locus_tag="VWX69_001399"
     CDS             13700..14305
                     /locus_tag="VWX69_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9192725.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(14253..>14811)
                     /locus_tag="VWX69_001400"
     CDS             complement(14253..>14811)
                     /locus_tag="VWX69_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9192726.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT         4828 a         2581 c         3070 g         4332 t
ORIGIN      
        1 tcaaatcgat ttctaacaat gttttagaaa tagaggtgta ctattctagt ttcaatatac
       61 tatatatctg cagaatactc tttcagtttc attcagccta gtcttgctta ggaaaaagta
      121 agaagccatc caattatgat ggatagcttc ttggttatta gatttgttct gcaaaaacct
      181 tttcagcaag gttcatagcg tggtctgata cacgagtgta gtgtgagatg atgtcgataa
      241 agttgacccc agcttgtgtt gaacattcgc ctttgttgag gcgtttgatg tgggtttttc
      301 tgagaacacg ttctatctta ttgattgctt catgacgttc tacaagactg cgtgcttttt
      361 caatatcatt gttttccaca ctatccagag catctttgat aaagtcacta gtttggcggt
      421 aaacttcctc taattctttc aaggcggcat cagaaaattc aacatttttc cgttgaagat
      481 agtcagtcag attgagtaga gcctccgtgt ggtctccaat ccgttccaaa tcacgggagg
      541 aatcaaggat attggtgagc acttcacttt ctttttggct gagagcttcg cttgaaaggg
      601 caatgagata acgtgttaat tgctcatcga tggtgttaat tgcttcttcg gttttatgcc
      661 ctttttcagc aactttttca tccaagtcaa tgatgtactt ataggaaagg tcaaaggctt
      721 tagcagcgta gtttcctaag tgcaagagct cttttttagc atttcctaga gcgatagatg
      781 gggcttgttt gatgaaatgt tcatcaagat ataagggttc gtatttgaca acctcgtcct
      841 ctccaggaat aatcttggtt acaaagtaag ccagagctcc gataaatgga aattggacaa
      901 tggtgttggt aatattaagg ttccgtgagc aaaggcgatg gtcatttccg gtgctagatt
      961 tagcgtagct tcaaaccaat gaatcaggac agtaaaagga actagaaaaa taacgcagac
     1021 gactgttccg ataacgttga aggcaacatg agctcctgct acccgtttag ctgcaatatt
     1081 agcccctaaa gaggcaatga tggctgtaat ggttgtcccg atattgtcac caaatagaac
     1141 tggcaaagct ccctgtaggt caattagatt gccggcgtag aggttttgta aaatcccaat
     1201 ggtagccgaa gaagcttgaa ttagcaaggt caagccggta ccgacaaaga cacccaaaac
     1261 aggattctta cttagctcaa tcatatagtc cttaaagacc tgtaaatcct tgagtggagc
     1321 cattgcgccg ctcatgagat tgagggcaaa aaagatacca ccgacaccaa agaggatgcg
     1381 tccgatatta ttgactgtcc gatttttcgt aaaaaagaga cagacggcac cgataaagag
     1441 cataggtagg gcatagttac ctaatttaaa accgatgaga aaggatgtga cagttgtccc
     1501 aatattagca cccatgacaa tcccgatagc ctgacgtaag gttaagagac cggcactgac
     1561 caggccgact gtaataactg ttacaccaga actagactga attagagcag tcatcccaat
     1621 accaaccaga actccaaaga aaggattact agtatatttg tcaatgtaaa aacgaaggcg
     1681 atctccagca gcttgttgca aaccgtctcc catggtcttg atgctatata agaatagccc
     1741 cagaccacct aaaaagtgaa ataaaatttc ctgccaatta atggacattt ctttttcctc
     1801 cgaaaaataa tcgcggaata tctcctattc tattttaaag gataaaagta aatctaacaa
     1861 gtgttaatgt caagtttgta aaagaaaatt ataattgata agtgtattat ttttaagagt
     1921 ttttaacctt attttagatt tgtgcaaaca gttattgttt tttgtctaaa aatgttttag
     1981 gataaaaatg tgattatcat ggttctagag tttgataaaa aactacagaa tataaagcgc
     2041 tttctttaaa acaacaaaat caatctttta ggaggagaaa atgaagaatc cattttttga
     2101 aagacgttgt cgttacagta ttcgtaagtt atcagtagga gcctgctcgc tgatgattgg
     2161 tgctgtttta tttgctggtc cagccttggc tgaagaaact gcagttcctg aaaatagcgg
     2221 agctaataca gagcttgttt caggagagag tgagcattcg accaatgaag ctgataagca
     2281 gaatgaaggg gaacatgcta gagaaaacaa gctagaaaag gcagaagcag ctagcgcagc
     2341 taaaccagag gaaaaagcag gtgaggtggt tgcagaaaca ccatctgcag aagcaaaacc
     2401 taagtctgac aaggaaacag aagcaaagcc cgaagcaact aaccaagggg atgagtctaa
     2461 gccagcagca gaagctaata agactgaaaa agaagtccag ccagatgtcc ctaaaaatac
     2521 agaaaaaaca ttaaaaccaa aggaaatcaa atttaattct tgggaagaat tgttaaaatg
     2581 ggaaccaggt gctcgtgaag atgatgctat taaccgcgga tctgttgtcc tcgcttcacg
     2641 tcggacaggt catttagtca atgaaaaagc tagcaaggaa gcaaaagttc aagccttatc
     2701 aaacaccaat tctaaagcaa aagaccatgc ttctgttggt ggagaagagt tcaaggccta
     2761 tgcttttgac tattggcaat atctagattc aatggtcttc tgggaaggtc tcgtaccaac
     2821 tcctgacgtt attgatgcag gtcaccgtaa cggggttcct gtatacggta cactcttctt
     2881 caactggtct aatagtattg cagatcaaga aagatttgct gaagctttga agcaagacgc
     2941 agatggtagc ttcccaattg cccgtaaatt ggtagacatg gccaagtatt atggctatga
     3001 tggctatttc atcaaccaag aaacaactgg agatttggtt aaacctcttg gagaaaagat
     3061 gcgccagttt atgctctata gcaaggaata tgctgctaag gtaaaccatc caatcaagta
     3121 ttcttggtat gatgccatga cctataacta tggacgttac catcaagatg gtttgggaga
     3181 atacaactac caattcatgc aaccagaagg agataaggtt ccggcagata acttctttgc
     3241 taactttaac tgggataagg ctaaaaatga ttacactatt gcaactgcca actggattgg
     3301 tcgtaatcct tatgatgtat ttgcaggttt ggaattgcaa cagggtggtt cctacaagac
     3361 aaaggttaag tggaatgaca ttttagacga aaatgggaaa ttgcgccttt ctcttggttt
     3421 atttgcccca gataccatta caagtttagg aaaaactggt gaagattatc ataaaaatga
     3481 agatatcttc tttacaggtt atcaaggaga ccctactggt caaaaaccag gtgacaaaga
     3541 ttggtatggt attgctaacc tagttgcgga ccgtacgcca gcggtaggta atacttttac
     3601 tacttctttt aatacaggtc atggtaaaaa atggttcgta gatggtaagg tttctaagga
     3661 ttctgagtgg aattatcgtt cagtatcagg tgttcttcca acatggcgct ggtggcagac
     3721 ttcaacaggg gaaaaacttc gtgcagaata tgattttaca gatgcctata atggcggaaa
     3781 ttcccttaaa ttctctggtg atgtagccgg taagacagat caggatgtga gactttattc
     3841 tactaagtta gaagtaactg agaagaccaa acttcgtgtt gcccacaagg gaggaaaagg
     3901 ttctaaagtt tatatggcat tctctacaac tccagactac aaattcgatg atgcagatgc
     3961 atggaaagag ctaacccttt ctgacaactg gacaaatgaa gaatttgatc tcagctcact
     4021 agcaggtaaa accatctatg cagtcaaact atttttcgag catgaaggtg ctgtaaaaga
     4081 ttatcggttc aacctaggac aattaactat ctcggacaat caccaagagc cacaatcgcc
     4141 gacaagcttt tctgtagtga aacaatctct taaaaatgcc caagaagcgg aagcagttgt
     4201 gcaatttaaa ggcaacaagg atgcagattt ctatgaagtt tatgaaaaag atggagacag
     4261 ctggaaatta ctaactggct catcttctac aactatttat ctaccaaaag ttagccgctc
     4321 agcaagtgct cagggtacaa ctcaagaact gaaggttgta gcagtcggta aaaatggagt
     4381 tcgttcagaa gctgcaacca caacctttga gtgggggatg actgtccaag acacaagtct
     4441 tccaagacct ctagcagaaa acatcgttcc aggggctact gttatcggaa gtaccttccc
     4501 agatacagaa ggtggagaag gtattgaagg tatgttgaac ggtaccatta ctagcttgtc
     4561 agataaatgg tcttcagctc agttgagtgg tagtgtggat attcgtttga ccaagccacg
     4621 taccgttgtt agatgggtca tggatcatgc aggggctggt ggtgagtctg ttaacgatgg
     4681 cttgatgaac accaaagact ttgaccttta ttataaagat gcagatggtg agtggaagct
     4741 agctaaggaa gtccgtggca acaaagcaca cgtgacagat atcactcttg ataaaccaat
     4801 cactgctcaa gactggcgct tgaatgttgt cacttctgac aatggaactc catggaaggc
     4861 tattcgtatc tataactgga aaatgtatga aaagcttgat actgagagtg tcaatattcc
     4921 gatggccaag gctgcagccc gttctctagg caataacaag gtacaagttg gctttgcaga
     4981 tgtaccggct ggagcaacta ttaccgttta tgataatcca aattctcaaa ctccactcgc
     5041 aaccttgaag agcgaagttg gaggagacct agcaagtgca ccattggatt tgacaaatca
     5101 atctggtctt ctttattatc gtacccagtt gccaggcaag gaaattagta atgtcctagc
     5161 agtttccgtt ccaaaagatg acagaagaat caagtcagtc agcctagaaa caggacctaa
     5221 gaaaacaagc tacgccgaag gggaggattt ggaccttaga ggtggtgttc ttcgagttca
     5281 gtatgaagga ggaactgagg acgaactcat tcgcctaact cacgcaggtg tatcagtatc
     5341 aggttttgat acgcatcata agggagaaca gaatcttact ctccaatatt tgggacaacc
     5401 agtaaatgct aatttgtcag tgactgtcac tggccaagac gaagcaagtc cgaaaactat
     5461 tttgggaatt gaagtaagtc aggaaccgaa aaaagattac ctagttggtg atagcttaga
     5521 cttgtctgaa ggacgctttg cagtggctta tagcaatgac accatggaag aacattcctt
     5581 tactgatgag ggagttgaaa tttctggtta cgatgctcaa aagactggtc gtcaaacctt
     5641 gacgcttcgt taccaaggtc atgaagtcaa ctttgatgtt ttggtatctc caaaagcagc
     5701 attgaacgat gagtacctca aacaaaaatt agcagaagtt gaagctgcta agaacaaggt
     5761 ggtctataac tttgcttcac cagaagtaaa agaagctttc ttgaaagcaa ttgaagcggc
     5821 cgaacaagtg ttgaaagacc atgaaactag cacccaagat caagtcaatg accgacttaa
     5881 taaattgaca gaagctcata aagctctgaa tggtcaagag aaatttaagg aagaaaagac
     5941 agagcttgat cgtttaacag gtgaggttca agaactcttg gctgccaaac caaaccatcc
     6001 ttcaggttct gccctagctc cgcttcttga gaaaaacaag gccttggttg aaaaagtaga
     6061 tttgagtcca gaagagcttg caacagcgaa acagagtcta aaagatctgg ttgctttatt
     6121 gaaagaagac aagccagcag tcttttctga tagtaaaaca ggtgttgaag tacacttctc
     6181 aaataaagag aagactgtca tcaagggttt gaaagtagag cgtgttcaag caagtgctga
     6241 agagaagaaa tactttgctg gagaagatgc tcatgtcttt gaaatagaag gtttggatga
     6301 aaaaggtcaa gatgttgatc tctcttatgc ttctattgtg aaaatcccaa ttgaaaaaga
     6361 taagaaagtt aagaaagtat ttttcttacc tgaaggcaaa gaggcagtag aattggcttt
     6421 tgaacaaacg gatagtcatg ttatctttac agcacctcac tttactcatt atgcctttgt
     6481 ttatgaatct gctgaaaaac cacaacctgc taaaccagca ccacaaaaca cagtccttcc
     6541 aaaacctact tatcaaccgg cttctgatca acaaaaggct cctaaattgg aagttcaaga
     6601 ggaaaaggtt gcctttcatc gtcaagagca tgaaaatgct gagatgctag ttggggaaca
     6661 acgagtcatc atacagggac gagatggact gttaagacat gtctttgaag ttgatgaaaa
     6721 cggtcagcgt cgtcttcgtt caacagaagt catccaagaa gcgattccag aaattgttga
     6781 aattggaaca aaagtaaaaa cagtaccagc agtagtagct acacaggaaa aaccagctca
     6841 aaatacagca gttaaatcag aagaagcaag caaacaattg ccaaatacag gaacagctga
     6901 tgctaatgaa gccctaatag caggcttagc cagccttggt cttgctagtt tagccttgac
     6961 cttgagacgg aaaagagaag ataaagatta aatatcgaaa aatcttgtga aatctttcct
     7021 tatatttcta aagtgtgata taatagtttc gaataaaata aataaaggag tttttgtaac
     7081 atggcaaaac ttactgttaa agacgttgac ttgaaaggta aaaaagtcct cgttcgtgtt
     7141 gacttcaacg taccattgaa agatggtgta atcactaacg ataaccgtat cacagcagct
     7201 cttccaacta ttaagtacat catcgaacaa ggtggacgtg caattctttt ctctcacctt
     7261 ggacgtgtga aagaagaagc tgataaagct ggtaaatcac ttgctcctgt agcagctgac
     7321 ttggcagcaa aacttggtca agatgttgtt ttcccaggtg tcactcgtgg tgctgaattg
     7381 gaagcggcaa tcaacgctct tgaagatgga caagttctct tggttgaaaa cactcgttac
     7441 gaagatgttg acggcaagaa agaatctaaa aacgatcctg aacttggtaa atactgggca
     7501 tcacttggag atggtatctt cgtaaacgat gcattcggta cagctcaccg tgcacacgca
     7561 tctaacgttg gtatctcagc aaacgttgaa aaagcagttg ctggtttcct tcttgaaaac
     7621 gaaattgcct acatccaaga agcagttgaa actccagaac gtccattcgt ggctatcctt
     7681 ggtggttcaa aagtttcaga caagatcggt gttatcgaaa acttgcttga aaaagctgat
     7741 aaagtcctta tcggtggtgg gatgacttac acattctaca aagcacaagg tatcgaaatc
     7801 ggtaactcac ttgtagaaga agacaaattg gatgttgcga aagctcttct tgaaaaagca
     7861 aatggtaaat tgatcttgcc agttgactca aaagaagcta acgcatttgc tggttacact
     7921 gaagtgcgtg acactgaagg tgaagcagtt tctgaaggct tccttggtct tgacatcggt
     7981 ccaaaatcta tcgccaaatt tgacgaagct ttgactggtg ccaaaacagt tgtatggaac
     8041 ggacctatgg gtgtatttga aaacccagat ttccaagctg gtacaatcgg tgtgatggac
     8101 gctatcgtga aacaaccagg agttaaatca atcatcggtg gtggtgactc agctgccgca
     8161 gcgattaacc ttggccgtgc agacaagttc tcatggatta gtacgggtgg tggagcatca
     8221 atggaacttc ttgaaggtaa ggttcttcca ggacttgtag ccttgacaga aaaataagat
     8281 tttataaaca aatcaaagaa gagagggatg aaagttcctc ttttcttttg cttaaaataa
     8341 aaacgcttcc tctcaactat tactcataaa aatcaccgat ttatgataaa atggaaatag
     8401 aaagttgaga ttatgagtta ttttaaaaaa tataaattcg ataaatccca gttcaaactt
     8461 ggtatgcgaa cctttaaaac aggtattgct gtttttctag ttctcttgat ttttggcttt
     8521 tttggctgga aaggtcttca aattggtgct ttgacagccg tttttagcct gagggagagt
     8581 tttgatgaga gtgttcattt tgggacttcg cgtattctag gaaatagtat cggtggactc
     8641 tatgccttgg tcttcttctt attaaatacc tttttccacg aagccttttg ggtgaccttg
     8701 gtagttgttc caatctgcac catgttaacc attatgacaa atgtagccat gaataacaaa
     8761 gcaggggtta ttggtggtgt agcagctatg ttaattatta ccctatcaat tccaagtggt
     8821 gagacaattt tgtacgtgtt tgtgcgtgta ttagaaacat ttatgggagt ttttgtcgca
     8881 attatcgtaa attacgatat tgatcgtatt cgtctctttt tagagaaaaa agaaaaataa
     8941 tgttacattt tataacatta ttaattgacg tttgtctttt tttagactat aatagacaga
     9001 aagaaggaaa ttgtaaatga aggaaaaaga atttcgccga aatatggctg tttttcctat
     9061 cggcagtgtt atgaagttga ccgatctatc ggcgcgtcag attcgttatt atgaaaatca
     9121 agagttgatc aagcccgatc gaaacgaagg aaatcgtcgc atgtattcct tgaatgacat
     9181 ggatcgtctg cttgaaatca aagattatat ctctgaaggt tataatatcg ctgccattaa
     9241 gaaaaaatat gctgaacgtg aagcgaaatc caagaaagcg gttagtcaga ctgaagtacg
     9301 tcgtgcactt cacaatgaac tcctccaaca ggggcgtttt gcttcagtac agtcaccttt
     9361 tggtcgcggt taggcaaccg caagtagtca tagattaagg agaaaactta tgccaatcac
     9421 agctgcagat attcgtcgtg aagtcaagga aaaaaatgtt acctttattc gtcttatgtt
     9481 ctcagatatt ttgggaacca tgaaaaacgt cgaaattcct gctacagatg aacagttaga
     9541 taaggtcttg tcgaacaagg ttatgtttga tggatcttct attgaaggtt ttgtacgtat
     9601 caatgagtcg gatatgtact tgtacccgga cttggataca tggacagtct tcccttgggg
     9661 agatgaaaat ggaagtgttg caggtctgat ctgtgatgtt tatacaacag aaggtgaacc
     9721 atttgcgggt gaccctcgtg gtaatttgaa acgagctctt cgtcacatgg aagaagttgg
     9781 attcaaatcc ttcaaccttg gtccagagcc agaattcttc ctatttaagt tggatgaaaa
     9841 tggggaccca acacttgaag tgaatgacaa gggtggctac tttgatttgg cacctactga
     9901 ccttgcggac aacacacgtc gtgagattgt gaatgtcttg accaaaatgg gatttgaagt
     9961 agaagcgagt caccacgagg ttgcggttgg acagcatgag attgacttta agtacgatga
    10021 agttctccgt gcttgtgata agattcaaat ctttaaactt gttgttaaaa ccattgctcg
    10081 caaacacgga ctttacgcaa catttatggc gaagccaaaa tttggtattg ctggctcagg
    10141 tatgcactgt aatatgtcct tgtttgatgc agaaggaaat aacgccttct ttgatccaaa
    10201 tgatccaaaa ggaatgcagt tgtcagaaac agcttaccat ttcctaggcg gtttgatcaa
    10261 gcatgcttac aactatactg ccatcatgaa cccaacagtt aactcataca aacgtttggt
    10321 tccaggttat gaagcgcctg tttacattgc ttgggctggt cgtaaccgtt cgccacttgt
    10381 gcgcgtacct gcttcacgtg gtatgggaac tcgtcttgag ttgcgttcag tggatccaat
    10441 ggcgaaccct tacgttgcta tggctgttct tttggaagtt ggtttgtatg gtattgaaaa
    10501 taaaatcgaa gcaccagctc ctatcgaaga aaatatctac atcatgacag cagaagagcg
    10561 caaggaagct ggtattacag accttccatc aactcttcac aacgctttga aagctttgac
    10621 agaagatgaa gtggttaaag ctgctctcgg agatcacatc tatactagct tccttgaagc
    10681 caaacgaatc gaatgggcaa gttatgcaac cttcgtttca caatgggaaa ttgataatta
    10741 tttagacctt tactaatact aatatagaag aaagattgcc tgtgggtaaa cagtcacaca
    10801 gcagtctaag ccatcaaata cctataaccc ttaaaatagc gatttcggtc gctatttatt
    10861 tttcgaaaaa tcctcttgac tcttttgcga attagattta tcatcagacg tgtagaagaa
    10921 aattaaggag tcactatgga aaaattcaat ttcaaaaaca atatcgggca agaaaacaag
    10981 ttacttcaaa tcgaaatcta caagtttact aacttttgca agcttcaaaa ttacacatct
    11041 gtaaatattt tttcgaaaga tatatttgaa gccatagtaa attgagacta gaatagtaca
    11101 ctacatctgc taaaaatttc tagaaactaa tttaactttc ctaatcgatt tgtttacatc
    11161 ttatttcaat ctactatatt atctcaataa atgatgatgg cgactgtttt gtttgtgctt
    11221 gtcgattttt gaatcctgat cgagcggaag aatatttctg ccgaggttgc caaggggaaa
    11281 atcctgaaga tattgaattt tatgatgaac aattacaggc agaaaaggtg gaggttttga
    11341 atattcgatt ggaagtaaaa aattgaatta tctacaatct catcaacaat aaacctattt
    11401 caaccccatt atctataggc gtatttttac gcctttttat atacttgaag cacataagaa
    11461 acattatggg aagtttgctg atggaagcac tcaagaaatt gatgttcctt atgatattcc
    11521 tgatacttgg gagtgggtga ggttttctac attggttgaa attgtcagag gtggctctcc
    11581 acgaccaatc aaagattatc ttacttctga agtagatgga ataaattgga taaaaatagg
    11641 tgatactgaa aagggtgaaa agtatataaa taatgttaaa gaaaaaatca aaaaatcagg
    11701 gcttaacaaa actagatttg taaaaaaagg tacatttttg ttaactaatt ctatgagttt
    11761 tggtagacct tatattttga atgttgatgg tgcaatacac gatggatggt tggctatttc
    11821 gaactatgaa aactcattaa ataaagatta cctattctat attctttcat caaatgtagt
    11881 ttattctcaa tttctatctc taattagtgg agctgttgtg aaaaacttga atagtgataa
    11941 agttgcttct attcttatcc ctctcccccc actatccgaa caacaacgca taatagaagc
    12001 aatcgaatca gctttagaaa aagtagatga atatgctgaa agttataata gactagaaca
    12061 gctagataaa gaatttccag ataaactaaa aaaatctatt cttcaatatg ctatgcaagg
    12121 aaaattagtt gaacaagacc caaatgatga atcagtcgaa gttttacttg aaaaaatacg
    12181 agcagaaaaa caaaaactct ttgaagaagg caagattaaa aagaaagatt tggacatttc
    12241 tattgtttcc caaggagatg ataactctta ttatgaggaa gtaccttgtg aaataccaga
    12301 aagttgggaa tgggtgaggt taaacgatat aacctcctac attcaaagag ggaagtctcc
    12361 aaaatattca aatattccta tataccctgt gattgctcag aaatgtaatc aatggtctgg
    12421 cttttctatt gacttagcaa gatttattga tcccgaaaca gttcatagtt accagaaaga
    12481 aagattacta agagatggtg atttaatgtg gaattcaaca ggtctaggta cgttaggacg
    12541 attagctatt taccatgaaa ataaaaatcc ttatggctgg gctgttgcag atagccatgt
    12601 tacagttata agagtcttat cgggagttat taattgccat ttcatctata attttctttc
    12661 ctctcctatt gttcagtcag ttattgaaga aaaagcgtcg ggtagtacaa aacaaaaaga
    12721 attattaacg aaaactataa aagaatattt aatccccctc ccaccccttc ctgaacaatc
    12781 cagaatcgtt gataaaatcg aacaattttt cgcccatatt gacgcactaa tttagtataa
    12841 tagttttacg tgcggtggaa tttctatcaa acataagata ggagttttac gttgaaagat
    12901 tttgaattac atttgaagaa agctggttta gctgaaaata ctgtgcgttc gtacctttat
    12961 ggtgttcgat ttttcttgga gaattacgaa ctcaaaatgg aagatttatt tgaatacaaa
    13021 ggatatttat tagacaattt taaacctaaa actgtcaatt tgcgactaca aggagtaaat
    13081 aaatatctgg cttttattgg tcatgatgat ttgaaattaa aatttgtcaa agtacagcaa
    13141 aaaccatttt tagaagatgt cattagccat gctgattacc tttttcttaa acgtagtttg
    13201 aaaaaagatg gtattttaaa atggcatttt gtcgtttggt ttttaggtgc aactggggct
    13261 cgtgtaagtg aacttattaa actaaaagta gagcatgtag aaatcggtta ttttgacatt
    13321 tactcaaaag gtggtaaaat tcgtagactg tacattccta aaaaattaag aaatagttgt
    13381 cttagttggt tagaatcaga aaatcgccga agtggttatt tatttttgaa taaatttaac
    13441 gaaccaatta cagcaagagg agttgctcaa cagttaaaaa attatgctga taaatacaaa
    13501 atgaatccta aagtaattta ccctcattct tttaggcatt tatttgctaa gaatttttta
    13561 gcgaagtata atgatattgc cttgcttgca gatttgatgg gacacgaaag tatagaaact
    13621 actcgaattt atctaaggaa aacagctact gaacaacaaa atattgtaga taaaattgtt
    13681 aattggtaaa aaataacagg tggtcaaact gactacctgc tatttttgtg attatggctc
    13741 ttattatggg aatataccta tgaattgggt tgttataaaa ataaaagata ttttttcaat
    13801 gaatacaggt ctttcttaca agaagggcga tttaagcatt aataataaag gtgttagaat
    13861 tatacgtggt ggtaatatta agcctttaga attttctctg ttggataatg attactacat
    13921 tgatacacaa ttcatctcct ctgaacaagt ttatttaaaa cataatcagc taataacacc
    13981 tgtatcaacc tctttagaac atattggaaa gtttgcaaga atcgataaag actatgatgg
    14041 tgttgtggct ggtggattta ttttccaatt aacaccattc gaaagttcag agattatttc
    14101 aaaatttcta ttatttaact tgtcctctcc gttattttat aaacaattga aagcaataac
    14161 taaactatca ggtcaagctt tatataatat tcctaaaact acactaagcg agctattaat
    14221 tccgttagct ccttttgagg aacaggaact tattactcaa aaagttgaga aactttttga
    14281 aaaagtaaat caactttgga aatgattctt ttcatctctt catgattaga aatagggatt
    14341 aataattcgg agatactggt actatttaat gttttccctt ttatagcatc ttttgaatca
    14401 cctaaagtag agataagtgg caaaaatatc attaagtaat ctctgataat attttcttta
    14461 ttagcatagg ggaatatcga tataatggct tcattatgag tggcaggaat atccaatatg
    14521 gcaacttttc caatagataa tttaaaactc attaataaag ttcctttagg tgaaatgtct
    14581 attttctttg attttaatgc taatttagaa atagattctc tcgtattagt tacataacca
    14641 gatataggca tatctgatat agatacccaa ggtatttcag ttccccaaaa agtagcttca
    14701 ctgcgtggag gagtttttcc tattctgaag ttaactaggc tagcaaattt aatatatctc
    14761 catgcttctg ggatttcata tataggataa gaggttgttt cgtctttgtt c
//
LOCUS       DAVKBK010000039        14624 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVKBK010000039 DAVKBK010000000
VERSION     DAVKBK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.039"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            221..2008
                     /locus_tag="VWX69_001401"
     CDS             221..2008
                     /locus_tag="VWX69_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU9192727.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            2005..2481
                     /locus_tag="VWX69_001402"
     CDS             2005..2481
                     /locus_tag="VWX69_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9192728.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            2509..3414
                     /locus_tag="VWX69_001403"
     CDS             2509..3414
                     /locus_tag="VWX69_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9192729.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            3401..4216
                     /locus_tag="VWX69_001404"
     CDS             3401..4216
                     /locus_tag="VWX69_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9192730.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALTLSALGHFALGM"
     gene            4223..4627
                     /locus_tag="VWX69_001405"
     CDS             4223..4627
                     /locus_tag="VWX69_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9192731.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            4925..6091
                     /locus_tag="VWX69_001406"
     CDS             4925..6091
                     /locus_tag="VWX69_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU9192732.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKKLVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALDCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            6207..7244
                     /locus_tag="VWX69_001407"
     CDS             6207..7244
                     /locus_tag="VWX69_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU9192733.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            7451..8305
                     /locus_tag="VWX69_001408"
     CDS             7451..8305
                     /locus_tag="VWX69_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9192734.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            8455..8712
                     /locus_tag="VWX69_001409"
     CDS             8455..8712
                     /locus_tag="VWX69_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU9192735.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADLVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(8754..9071)
                     /locus_tag="VWX69_001410"
     CDS             complement(8754..9071)
                     /locus_tag="VWX69_001410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192736.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDRTDEVSNHIYGKVKLTWFEEI
                     FEEYKSPHNKTHTIKVFMYCPPKVRQKKSNFWGQYISIPDTMRFFNFKDFLQLLLTHI
                     KLF"
     gene            complement(9143..9421)
                     /locus_tag="VWX69_001411"
     CDS             complement(9143..9421)
                     /locus_tag="VWX69_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9192737.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNA"
     gene            9643..10407
                     /locus_tag="VWX69_001412"
     CDS             9643..10407
                     /locus_tag="VWX69_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU9192738.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(10647..10934)
                     /locus_tag="VWX69_001413"
     CDS             complement(10647..10934)
                     /locus_tag="VWX69_001413"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192739.1"
                     /translation="MKTKASIRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADKTDEVS
                     SKHCFEVADKTDEVSSKHCFEVADKTDEVSSKHCFEVADRTDEVSNIYTAR"
     gene            11152..12531
                     /locus_tag="VWX69_001414"
     CDS             11152..12531
                     /locus_tag="VWX69_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9192740.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            12545..13210
                     /locus_tag="VWX69_001415"
     CDS             12545..13210
                     /locus_tag="VWX69_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU9192741.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            13324..13419
                     /locus_tag="VWX69_001416"
                     /pseudo
     CDS             13324..13419
                     /locus_tag="VWX69_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            13610..14149
                     /locus_tag="VWX69_001417"
     CDS             13610..14149
                     /locus_tag="VWX69_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9192742.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            14216..>14624
                     /locus_tag="VWX69_001418"
     CDS             14216..>14624
                     /locus_tag="VWX69_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU9192743.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLY
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
BASE COUNT         4022 a         2770 c         3350 g         4482 t
ORIGIN      
        1 tatcaatgca ttctatacaa aattatttta ggtcctatat tccgaattta aagagcgttt
       61 gaaatgggtc taaaaatgtt tgaaactaat tgaatgtgtg tataatagta aaaatgcagt
      121 aaatatcccg acaatttcta ttgacaattc aaacagattg gtttataatt aatataacaa
      181 caaatgaaag cgcaaacttt cgcggtcgga aggtagtttt atgacacgat ttgagatacg
      241 agatgatttc tatctcgatg gaaaatcatt taagatttta tctggtgcca ttcattattt
      301 taggattcct ccagaggatt ggtatcattc gctctataac ttgaaggctc ttggttttaa
      361 tacggtagag acttatgttg cttggaattt acacgagcct cgtgaaggtg agtttcattt
      421 tgaaggtgat ctggatttag agaaatttct ccaaatagcg caggatttgg gtctctacgc
      481 aattgtgcgt ccgtctccat ttatctgtgc ggaatgggaa ttcggtggct taccagcttg
      541 gctcttgacc aagaacatgc gaattcgctc atccgaccca gcatatatcg aggcagttgg
      601 tcgctactat gatcagttat tgccaagact ggtgcctcgt ttgttgaaca atggtggcaa
      661 tattctcatg atgcaggttg aaaatgagta tggttcttac ggagaagata aggcttacct
      721 gagagcgatt cgacagctaa tggaagagtg tggcgtaacc tgtcccctct ttacatcaga
      781 tggtccatgg cgagctactc tgaaagctgg aaccttaatt gaagaggacc tctttgtaac
      841 aggaaacttt ggttctaagg caccttacaa cttttcgcag atgcaggaat tctttgatga
      901 acatggtaag aaatggccac tcatgtgtat ggagttctgg gatggttggt tcaatcgctg
      961 gaaagaaccg attatcacac gggatcctaa ggaattggca gatgcagttc gagaggtttt
     1021 ggaacaaggc tctatcaatc tttacatgtt ccacggtggt acaaactttg gtttcatgaa
     1081 tggttgctca gctcgaggaa ctttggacct gccacaagtt acatcttatg attacgatgc
     1141 ccttctggat gaagaaggaa atccaactgc taaatatctt gcagtcaaga agatgatggc
     1201 aacacatttt tcagagtatc cgcagttgga accactctac aaagagagta tggagttgga
     1261 tgctattcca ctagttgaaa aagtttcttt gtttgaaacc ttagatagct tgtcaagtcc
     1321 tgtagaaagt ctctatcctc aaaagatgga ggagctggga caaagttatg gctacctact
     1381 ttatcgaaca gaaacaaact gggatgcaga agaagaaaga cttcgtatca ttgatggtcg
     1441 agatagggcc cagctgtatg tcgatggtca gtgggttaaa actcaatatc agacagagat
     1501 tggggaagat attttttatc aaggtaaaaa gaaagggcta tctaggttag atatcttgat
     1561 agaaaatatg gggcgtgtca actatgggca taagttctta gcggatacgc aacgtaaggg
     1621 aattcggaca ggggtctgta aggatctgca tttcttacta aactggaaac actatccact
     1681 cccactagac aatcctgaga aaattgattt ttcaaaagga tggactcaag gacaaccagc
     1741 cttttacgct tatgacttta cagtcgaaga gccaaaagat acttacctag acttgtctga
     1801 gtttggtaag ggagttgcct ttgtcaatgg gcagaatcta ggacgttttt ggaacgttgg
     1861 cccaactctc tcactttata tccctcatag ctatctcaag gaaggtgcca accgtatcat
     1921 tatctttgaa acagaaggtc aatataaaga agagattcat ttaactcgta aacctacact
     1981 aaaacatata aagggggaaa acttatgaca attgtaggat gccgtattga tggacgtttg
     2041 atccacggac aagtagccaa tctttgggct ggaaaactaa atgtttcacg cattatggtt
     2101 gtagacgacg aagttgtcaa caacgatatt gaaaagagtg gtttgaaact tgcgacacca
     2161 ccaggtgtga aattgagtat tttgccagtt gagaaagctg cagccaatat tcttgctggt
     2221 aaatacgata gccaacgtct ctttatcgtg gctcgtaaac cagaccgctt ccttggtttg
     2281 gtagaagcag gtgtaccact tgaaaccctt aatgttggga atatgtctca aacaccagaa
     2341 actcgttcta ttacacgttc tatcaacgta gtagacaagg atgtggaaga cttccacaaa
     2401 ctggcagaaa aaggtgttaa acttactgct cagatggttc caaatgatcc aatttcagac
     2461 tttttgagct tattaaaata ggaaaaaaat ttttaggagg tcattgttat gatacaatgg
     2521 tggcaaattt tacttctcac tttgtactca gcttatcaaa tctgtgatga gttgacgatc
     2581 gtttcatctg caggttcccc tgtatttgct ggtttcatta ctggtttaat catgggagat
     2641 gtgactactg gtttacttat cggtggtaac ttgcaactgt tcgttcttgg ggttggtacc
     2701 ttcggtggtg cttctcgtat cgacgcaact tctggtgcgg ttcttgcgac agccttctct
     2761 gtttcacaag gaattgatgc accgcttgcc attactacaa tcgctgtacc agtagcagct
     2821 ctcttgactt acttcgacgt tcttggtcgt atgactacta ccttcttcgc tcaccgtgtg
     2881 gatgctgcaa tcgaacgctt tgactataaa ggtattgaac gcaactactt gcttggtgcg
     2941 attccgtggg ctctatctcg tgcccttcca gtcttctttg cccttgcttt tggtggtgcc
     3001 tttgtacaat cagtagtaga cttcgttgaa gcctacaaat gggttgcaga tggcttgaca
     3061 cttgcaggac gtatgcttcc aggtcttgga tttgcaatct tgcttcgtta ccttccagtt
     3121 aaacgtaacc ttcactacct tgctatggga tttggtttga cagctatgtt gactgttctt
     3181 tactcatatg taacaggtct tggtggcgct gttgctggta tcgtaggtac tcttcctgct
     3241 gaagttgctg aaaaaattgg tttcgtgaac aacttcaaag gtttgtctat gattggtatt
     3301 tctatcgtag gtattttcct tgcagtgctt cacttcaaaa atagccaaaa agtagctgta
     3361 gcagcacctt ctacaccatc agaaagtggg gaaatcgaag atgacgaatt ctaattacaa
     3421 acttacaaaa gaagatttta atcaaatcaa caaacgtagc ttgtttactt tccaattagg
     3481 ttggaactac gaacgtatgc aagcttctgg ttacctttac atgatcttgc ctcagttgcg
     3541 taaaatgtat ggtgatggaa ctcctgaatt gaaagaaatg atgaaagttc atactcaatt
     3601 cttcaatact tcaccattct tccataccat tatcgctggt tttgaccttg ccatggaaga
     3661 aaaagatggt gtaggttcaa aagacgctgt taacggtatc aagacaggtt tgatgggacc
     3721 attcgctcct cttggggata caatctttgg ttcacttgta cctgctatca tggggtcagt
     3781 cgcagcaact atggctatcg ctggccaacc ttgggggatc ttcctttgga ttgcagttgc
     3841 agtagcgtat gacatcttcc gttggaaaca gttggaattt gcttacaaag aaggggttaa
     3901 ccttatcaac aacatgcaaa gtaccttgac agctttgatt gacgctgcat ctgtacttgg
     3961 tgtcttcatg atgggtgctc ttgtagcaac agtgattaac tttgaaattt cttacaagtt
     4021 gccaatcggt gaaaagatga ttgatttcca agacatcttg aaccaaatct tcccacgttt
     4081 gcttccagca atctttactg cctttatctt ctggttgctt ggtaagaaag gtatgaactc
     4141 tactaaagct atcggtatta ttatcgtact tgctttgact ctttctgccc ttggtcactt
     4201 tgcacttgga atgtaattcc ttatgactaa atcattaatt ttggtgagcc atggtcgctt
     4261 ctgtgaggag cttagaggta gcacagaaat gattatgggc ccacaagaca acatttacac
     4321 agtagctctt cttccagaag atggcccaga agaatttact gctaaatttg aagctgttat
     4381 tggaggattg gatgatttcc tagtctttgc ggatcttctc ggtgggacac cttgtaatgt
     4441 ggtgagtcgc ttgatcatgg aaggtcgtga tattgacctt tacgcaggga tgaatcttcc
     4501 aatggtgatt gaatttatca atgcgagcct tacaggcgca gatgcggact acaagagccg
     4561 tgctgcagaa agcattgtga aagttaatga cctgttagcg ggcttcgatg atgacgaaga
     4621 tgaataatac tcttcgaaaa tctcttcaaa ctacgtcaac gtcgccttgc cgtaggtata
     4681 tgttactgac ttcgtcagtc ttatccggca acctcaaaac ggtgttttga gctgacttcg
     4741 tcagttctat ctgcaacctc aaagtagtgc tttgagcagc ctgcggctag tttcctacag
     4801 attttagttg gaactcgatt caattcatgt gacaacgtga aaatcgttag agcattttat
     4861 atagaatata catgggaatg gagcttactc ccattcccat atttaataga aaaagaggaa
     4921 ctcaatgcta cattatacaa aagaagactt gctcgaattg ggtgcagaaa tcactacgcg
     4981 tgaaatctac caacaacctg atgtatggag agaagctttt gaattttatc aagcaaaacg
     5041 tgaagaaatt gcagccttcc tacaagaaat cgctgataaa catgactata ttaaggttat
     5101 cttgacaggt gctgggactt ctgcttatgt gggagacacc ttgctacctt actttaagga
     5161 agtctatgac gaacgcaaat ggaatttcaa tgctattgcg acaacagata tcgttgccaa
     5221 tccagcaacc tatttgaaaa aagatgtggc aactgtcctt gtgtcttttg ctcgtagtgg
     5281 gaactcgcct gaaagtgtgg cgactgttga tttggccaaa tccttggtgg atgagcttta
     5341 tcaagtgacg attacttgtg cagcagatgg taaattggct cttcaagctc acggtgatga
     5401 ccgtaatctc ttgctcttgc aaccagctgt ctctaatgat gctggatttg ccatgacttc
     5461 tagctttacg tctatgatgt tgacagctct cttggtcttt gatcctacag aatttgctgt
     5521 taagtctgaa cgttttgaag ttgtatctag tcttgcccgt aaagttttag acaaggcaga
     5581 agatgtcaaa aagctcgttg atttagactt taaccgtgtc atctatctag gcgctggtcc
     5641 tttctttgga cttgctcatg aagctcagct caagattttg gaattaactg ctggtcaagt
     5701 tgcgaccatg tatgaaagcc cagttggctt ccgtcacggt ccaaaatctc ttatcaacga
     5761 caatacagtt gttttggtct ttggtacaac gacagactac actcgtaagt acgacttgga
     5821 cttggttcgt gaagttgctg gtgaccagat tgctcgtcgt gttgtgcttt tgagtgatca
     5881 agcttttggt cttgaaaatg tcaaagaagt ggcccttgat tgtggcggtg tcttgaatga
     5941 tatttaccgt gtcttccctt acatcgttta tgcccaactc tttgccctat tgacttcact
     6001 caaggtagaa aataaaccag atacaccgtc tcctacaggt acagtaaacc gtgtagtaca
     6061 aggtgtcata attcacgaat atcaaaagta agacagtgtt tatgaattct tgacaagagg
     6121 atttgtaaat tatcagataa accatagatt gtcagtacgc tttctatggt ttgtttgctt
     6181 gagagaaata gtaaaaggag aacagaatga aagcatacac agagcgtgta tttggaaatg
     6241 ttgagggcga ggatgtcttg gcctatcgat ttgagacaga cggtggctac caacttgagg
     6301 ttatgactta tggcgcgacc atcttgcgct atgtcgcacc tgacaaggct ggaaattttg
     6361 ccaatgttat cttgggattt gatgactttg atagttatgt aggcaatagt cccaagcatg
     6421 gagcaagtgt aggtcctgta gcgggtcgta ttgcaggtgc gacctttgag ctcaatggta
     6481 agacctatga ccttgaggtt aataatgcta gcaactgtaa tcacagtggt tcaactggtt
     6541 gggattccag cttgtttgaa gttgaagaag taagcgatca tggcttgact ctctacacag
     6601 agcgtacaga tgggacagga gggttccctg gaaatctcaa gatttggatc agttatcact
     6661 tggaagaaac tggtgcctat gaaatcagct acaaggtaac gaccgatcag gatacgctgg
     6721 tcaatccaac caaccacagc tatttcaact tgtctggtga tttcacgcag acgattgacc
     6781 gtcatgtctt ccaactaaac acagagggca tttactcaat cgctcctgac ggtgttcctg
     6841 ccaaaactcc agaagccaac cgtgatgtgg tcaaacacat ctacaatggt gccttgttga
     6901 aggatatctt tgcagaagaa gatgagcaaa tccagctggc atcaggtttg gatcatccat
     6961 ttgcccttcc tgcaggccat gacaatgctg gattccttta tgaccaaaat tcaggtcgct
     7021 tcctgctttt caagacagaa gctccttgct ttgtggtcta cacagcaaac tttgtggatg
     7081 aaagtgtcat cataggaggt cagccaatgc tacagcacaa tgggattgct cttgaagcgc
     7141 aagctttacc agatgccatt cacagtgacc ttaaaggcca agtcattctt aaagctggtc
     7201 aaaccttcac cagtaagaca cgttatgaac ttgttgtgaa ataaaaaagc tggtcaaaaa
     7261 gtctttaaaa ttaaaataac gcatattgtc aggtgatgaa aagtttgata atatgcgttt
     7321 tattatgaaa tgatttactt tatattatcc tgaaatggtg ttatttttga gttatctggc
     7381 ttgactttct tgatggaaat tatataatag ttgcaacaat aataattaca acgaaaaaag
     7441 aggaccattt atgacctatg aatacaagag tcacatttat ttggcagaga cagttttaaa
     7501 tgtaaaggat ttggccagtc aaacagcctt ttatcagcaa gttatcggtt tagaaatctt
     7561 atctcaaact gagacagagt ccattctagg ccttggtgga aaagtcttgg tacagctgat
     7621 tcaagcacaa gagagcggag aagtgaggga acattatggt ctttaccatt tggccattct
     7681 cttgcccaca cgcaaggctt tggctgatgt cttgaaacac ctgacagatt tacagattcc
     7741 tcttgtcggc ggtgcagacc atggttacag tgaagctatt tacttggaag atttggaggg
     7801 aaatggcatt gaactctatc gagataagcc agtttccaca tgggatattc gagaagatgg
     7861 acgcattatc ggagtgacgg aggctcttgc ggcgcaggac atttatgagt tgggggaaag
     7921 agtagagccc tttatcctgg cagaaggtac gagaatgggg catattcatc tttcagtcaa
     7981 ggatagtcga aagtccagcc agttttatca aaaggtgtta gggctagagg ataaattcag
     8041 tgtgcctagc gctagttgga ttgcggctgg agattaccat catcatttag cagttaacga
     8101 atggggagga aaaggtctgg cttcgcgtaa gcaaggctta ccaggtttag cctactatgt
     8161 catcgaagtc gcacataaaa aagaactgtt aacgattgcc caacgagcac aagaagttga
     8221 cgcaccaatc aaatggatga catcgagcca attggaaatc acagactcag atggcatcgt
     8281 gacccgtatt cgtttagcaa ggtaaaatta ggaattttta ataagttata agtattgcta
     8341 gtttgctttt tgaacggtct ttggtaacag aactgcgtga gctggatggg tgagaatttt
     8401 gacaaagaag ctgattagag atataatgaa gaaaagtcga gcaaggaaaa agaaatgaca
     8461 aattcaaagt atattacttg tttgaaacgt tcagagggcc agttgtgtgg gattcaaaag
     8521 atgattgaag gagatcgtga ctgtgctgat cttgtgacgc aactgacagc agtgagatct
     8581 agtgtagagc gcgtgattga gatgataatt accgaaaatc ttactgaatg tatcaatcag
     8641 ccactagatg attctgaagc tcaaaaggaa cgcttagaaa aggctatccg atacttgatt
     8701 aaacggaaat aaatgaatgt tttgagacga tatgtgcaaa ggtctattaa ctattagaat
     8761 agtttaatgt gagtcaaaag aagttgtaaa aaatctttaa aattaaaaaa acgcatagta
     8821 tcaggtattg aaatgtactg cccccaaaag ttagattttt tctgtctaac ttttgggggg
     8881 cagtacataa aaaccttgat agtatgcgtt ttattgtggg gagatttata ctcttcgaaa
     8941 atctcttcaa accacgtcag cttcaccttg ccgtagatat ggttactgac ttcgtcagtt
     9001 ctatccacaa ccttaaaaca gtgttttgag cagcctgcgg ctaacttcct agtttgcact
     9061 ttaattttca ttgagtatta cttcatcttc tcatgaaatt gagtttttgc ccagctcctc
     9121 ttgattattc tacttgaccg ggctaagcat tcataccacc ttctacgttg gtaacggtga
     9181 ggccttggga gctgagaaat tggcaggtag atgcagagcg gactcctcct tgacaaataa
     9241 catagtattc atggtcaggt ttgagttctt tgtagccttg ctctaaggta cttaatggaa
     9301 gatttttggc acctggtgca tgtcctgctt ggaattcatg tgcttcacgg acatcgataa
     9361 gttctagatt ttcattttga tattttccat aaaagtcagc catgctgata ctagtttcca
     9421 tattctactc cttctgggtt agccattttg tatagtgaat aagcgccgtc aaggttttgg
     9481 acggtaaatc ctgcttgctt gaggataggc tctgcgatat agctgcgcaa actactgtgg
     9541 caactgacga tgtaggcttg tttttctcct cagttcatca gcttcctcct tgacactcgg
     9601 tcagattttg atacaatagt acaaaattag aggaggtggg ctatgattca gaaacatgcg
     9661 attcccattt tagagtttga tgataatcct caggcggtta tcatgcccaa tcacgagggg
     9721 ttggatttgc agttgccaaa gaagtgtgtc tatgcttttt taggtgagga gattgaccgc
     9781 tatgcgaggg aagtaggggc gaactgtgtt ggcgaattcg tttctgctac caagacctat
     9841 ccagtctatg tcatcaacta caagggtgag gaggtctgtc tggctcaggc tcctgttggc
     9901 tccgctccag cagcccagtt tatggattgg ttgattggct atggtgtgga gcagattatc
     9961 tctactggga cctgtggtgt cctagctgat atagaggaaa atgcctttct agtccctgtt
    10021 cgcgctttgc gagatgaggg agccagttac cactatgtgg caccttgtcg ttatatggaa
    10081 atgcagccag aggctattgc tgctattgag gaagttttgg aagacagagg gattccttat
    10141 gaagaagtca tgacctggac gacagacggt ttttaccgag aaacggctga aaaggtggct
    10201 tatcgtaagg aagaaggctg tgctgttgtg gagatggagt gttctgctct tgctgcagta
    10261 gctcaattgc gtggggttct ctggggtgaa ttgttgttca cagcagattc tctagcggac
    10321 ttggaccagt acgacagtcg tgactggggc tcggaagctt ttaataaggc gctagaactg
    10381 agtttagcaa gtgttcacca cctttagttg tactggcaaa ggatttgttt tatcataaaa
    10441 tgtctagctc atacttttca aaaatatgtt taaacgaggt caccttcctc ttgtcctagg
    10501 catgttgagg ttgggaaaaa tctttaaaat cagaaaaacg tatcatatca ggtgatgaaa
    10561 attttgatac tatgcgtttt atgttggtaa gatttagagt gagatgaaat gatactcttc
    10621 gaaaatctct tcaaaccagg tcagcttcac cttgccgtat agatgttact gacttcgtca
    10681 gttctatctg caacctcaaa acagtgtttt gagctgactt cgtcagtttt atctgcaacc
    10741 tcaaaacagt gttttgagct gacttcgtca gttttatctg caacctcaaa acagtgtttt
    10801 gagctgactt cgtcagtttt atctgcaacc tcaaaacagt gttttgagct gacttcgtca
    10861 gttctatcca caacctcaaa acagtgtttt gagcaacctg tgactagctt tctaatcgat
    10921 gccttggttt tcattgccta taatcaaaaa gagaaatttt ctcctgaaaa gcatatagag
    10981 tagctggcgt taaaagctcc tgtcttgctt ttttgaccta tagtcatatc tatcaagtat
    11041 tgttcttgcc taagctatca ataaaaaggt ggcatttttt aggcttggtg ttagtgaatt
    11101 ttgccttatc ctatctaagt catttcgagc tttttatggt acaatggaaa catgttattc
    11161 aaattatcta aggaaaaaat agagctaggc ttatctcgtt tatcgccagc ccgtcgtatt
    11221 tttttgagtt ttgccttggt cattttacta ggctctcttc ttttgagctt gccctttgtc
    11281 caagttgaaa gctcacgagc gacttatttt gatcatcttt tcactgctgt ctctgcagtc
    11341 tgtgtgacag gtctctcaac ccttccagta gctcacacct ataatatctg gggccaaata
    11401 atctgtttgc tcttgattca gatcggtggt ctagggctca tgacctttat tggggttttc
    11461 tatatccaga gcaagcaaaa gcttagtctt cgtagccgtg caactattca ggatagtttt
    11521 agttatggag aaactcgatc tttgagaaag tttgtctatt ctatttttct cacgaccttt
    11581 ttggttgaga gcttgggagc tattttgctt agttttcgcc ttattcctca acttggctgg
    11641 ggacgtggtc tttttagttc catttttcta gcgatctcag ccttctgtaa tgccggtttt
    11701 gataatttag ggagcaccag tttatttgct tttcagaccg atttactggt caatctggtg
    11761 attgcaggct tgattattac aggcggcctt ggttttatgg tctggtttga tttggctggt
    11821 catgtaggaa gaaagaaaaa aggacgtctg cactttcata cgaagcttgt attattattg
    11881 actataggtt tgttgttatt tggaacggca actactctct ttcttgagtg gaacaatgct
    11941 ggaacgattg gcaatctccc tgttgccgat aaggttttag ttagcttttt tcaaacagtg
    12001 acgatgcgaa cagctggctt ttctacgata gattatactc aggctcatcc tgtgactctt
    12061 ttgatttata tcttacagat gtttctaggt ggggcacctg gaggaacagc tgggggactc
    12121 aagattacga cattttttgt cctcttggtc tttgcacgaa gtgagcttct aggcttgcct
    12181 catgccaatg ttgcgagacg aacgatcgcg ccgcgaacgg ttcaaaaatc ctttagtgtc
    12241 tttattatct ttttgatgag cttcttgata ggattgattc tgctagggat aacagccaaa
    12301 ggcaatcctc cctttatcca cctcatattt gaaaccattt cagctcttag tacagttggt
    12361 gtaacggcaa atctgactcc tgaccttggg aaattggctc tcagtgttat catgccactt
    12421 atgtttatgg gacgaattgg tcccttgacc ttgtttgtta gcttggcaga ttaccatcca
    12481 gaaaagaaag atatgattca ctatatgaaa gcagatatta gtattggtta agaaaggaaa
    12541 gagcatgtca gatcgtacga ttggaatttt gggcttggga atttttggga gcagtgtcct
    12601 agctgcccta gccaagcagg atatgaatat tatcgctatt gatgaccacg cagagcgcat
    12661 caatcagttt gagccagttt tggcgcgtgg agtgattggt gacatcacag atgaagaatt
    12721 attgagatca gcagggattg atacctgcga taccgttgta gtcgcgacag gtgaaaatct
    12781 ggagtcgagt gtgcttgcgg ttatgcactg taagagtttg ggggtaccga ctgttattgc
    12841 taaggtcaaa agtcagaccg ctaagaaagt gctagaaaag attggagctg actcggttat
    12901 ctcgccagag tatgaaatgg ggcagtctct agcacagacc attcttttcc ataatagtgt
    12961 tgatgtcttt cagttggata aaaatgtgtc tatcgtggag atgaaaattc ctcagtcttg
    13021 ggcaggtcaa agtctgagta aattagacct ccgtggcaaa tacaatctga atattttggg
    13081 tttccgagag caggaaaatt ccccattgga tgttgaattt ggaccagatg acctcttgaa
    13141 agcagatacc tatattttgg cagtcatcaa caaccagtat ttggataccc tagtagcatt
    13201 gaattcgtaa agagggatga cccctctttt ttgatgctta agatggcaaa tagagacaga
    13261 agccccttgt cttctagtaa aagttcttca aaggctggac tttatggtaa aatagaagga
    13321 agtgacaaga gagagtaata ctcaatgaaa atcaaagatc aaactaggaa actagctgcg
    13381 ggctgctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag ctcaaaacac
    13441 tgttttgagg ttgcagatag aactgacgaa gtcagctcaa aacactgttt tgaggttgca
    13501 gatagaactg acgaagtcag taacatctat acggcaaggc gacgttgacg cggtttgaag
    13561 agattttcga agagtataag aaaaaatcag tcccctaaag gagcagatta tgaagttatt
    13621 gtctatcgcc atttctagct ataatgcagc agcctatctt cattactgtg tggagtcgct
    13681 agtgattggt ggtgagcaag ttgggatttt gattatcaat gacgggtctc aggatcagac
    13741 tcaggaaatc gctgagtgtt tagctagcaa gtatcctaat atcgttagag ccatctatca
    13801 ggaaaataaa ggccatggcg gtgcggtcaa tcgtggcttg gcagaggctt ctgggcgcta
    13861 ttttaaagta gttgacagtg atgactgggt ggatcctcgt gcctacttga aaattcttga
    13921 aaccttgcag gaatttgaga gcaagggtca agaggtggat gtctttgtga ccaattttgt
    13981 ctatgaaaag gaaggtcagt cttgtaagaa gagtatgagt tacgattcag tcttgcctgt
    14041 tcggcagatt tttggctggg accaggtcgg aaatttctcc aaaggccagt atatcatgat
    14101 gcactcgctg atttatcgga cagatttgtt gcgtgctagc cagttctaat tgcctgaaca
    14161 tactttttat gtcgataatc tctttgtctt tacgcccctt cagcaggtca agaccatgta
    14221 ctatctgcct gtcgatttct atcgttattt gattgggcgt gaggaccagt ctgtcaatga
    14281 gcaagtgatg attaagtgca ttgaccagca actcaaggtc aatcgactct tggtagacca
    14341 actttatttg tcccaagtga gtcatcccaa aatgcgagaa tatctgctga atcatattga
    14401 aatcacgacg gtgatttcca gtaccctgct caaccgatct ggaacagcgg agcatctggc
    14461 aaaaaaacgc caattgtgga cctatattca gcagaaaaat ccagaagtct ttcaggctat
    14521 tcgtaagacc atgttgagcc gtttgaccaa acattctgtc ttgccagatc gcaaactgtc
    14581 caatgtcgtc tatcaaatca ccaaatctgt ttatggattt aatt
//
LOCUS       DAVKBK010000040        14238 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVKBK010000040 DAVKBK010000000
VERSION     DAVKBK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14238
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.040"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(778..1647)
                     /locus_tag="VWX69_001419"
     CDS             complement(778..1647)
                     /locus_tag="VWX69_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9192744.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIVA
                     AIAAVAVFKFLYL"
     gene            complement(1871..2392)
                     /locus_tag="VWX69_001420"
     CDS             complement(1871..2392)
                     /locus_tag="VWX69_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9192745.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAS
                     LGLGFFKKKEDEK"
     gene            complement(2350..3456)
                     /locus_tag="VWX69_001421"
     CDS             complement(2350..3456)
                     /locus_tag="VWX69_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU9192746.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVVVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(3567..3821)
                     /locus_tag="VWX69_001422"
     CDS             complement(3567..3821)
                     /locus_tag="VWX69_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192747.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(4161..4694)
                     /locus_tag="VWX69_001423"
     CDS             complement(4161..4694)
                     /locus_tag="VWX69_001423"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9192748.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYKKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(4681..4896)
                     /locus_tag="VWX69_001424"
     CDS             complement(4681..4896)
                     /locus_tag="VWX69_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9192749.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(4863..5006)
                     /locus_tag="VWX69_001425"
     CDS             complement(4863..5006)
                     /locus_tag="VWX69_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEU9192750.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            5240..6958
                     /locus_tag="VWX69_001426"
     CDS             5240..6958
                     /locus_tag="VWX69_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU9192751.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            7069..7416
                     /locus_tag="VWX69_001427"
     CDS             7069..7416
                     /locus_tag="VWX69_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9192752.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(7695..8531)
                     /locus_tag="VWX69_001428"
     CDS             complement(7695..8531)
                     /locus_tag="VWX69_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9192753.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(8544..9173)
                     /locus_tag="VWX69_001429"
     CDS             complement(8544..9173)
                     /locus_tag="VWX69_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9192754.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(9183..9824)
                     /locus_tag="VWX69_001430"
     CDS             complement(9183..9824)
                     /locus_tag="VWX69_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9192755.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(9970..11199)
                     /locus_tag="VWX69_001431"
     CDS             complement(9970..11199)
                     /locus_tag="VWX69_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU9192756.1"
                     /translation="MNNSQQMLQALEEQDLTKAEYYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(11189..12355)
                     /locus_tag="VWX69_001432"
     CDS             complement(11189..12355)
                     /locus_tag="VWX69_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9192757.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVIFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            12499..13512
                     /locus_tag="VWX69_001433"
     CDS             12499..13512
                     /locus_tag="VWX69_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU9192758.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNEFHVPEAVCIR
                     FAP"
     gene            13652..>14238
                     /locus_tag="VWX69_001434"
     CDS             13652..>14238
                     /locus_tag="VWX69_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9192759.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFL"
BASE COUNT         4365 a         3049 c         2494 g         4330 t
ORIGIN      
        1 taaaaattta actaattaat agaaagtact aaatagactt atccttcaag gagttttcag
       61 cattatccat ccactcactt gctgaaaatg taaacagtct ctggtttata tagtaaaatg
      121 aaacaagaat agagcaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
      181 gtagatgtgt actattctag tttcaatcta ctatacaacc tcaaaactgt gttttgaaca
      241 acctgcggct agcttcttag tttgcccttt gattttcatt gagtataaaa ttgcagataa
      301 aacgataaca atcataggac tcagcagagt caatgtaggt cgaagaatac ccccctaatc
      361 gcttatttta tagcaaaatg aaatagaaac tgaacatttt gttgaggaag gtaaatcaat
      421 tcctcacaat gtttgagaaa gaagggagga ctattccaac ttcaacccac tataaagcag
      481 acttacaaga tagggaaccc atctccgata atatatagta gaatgaaaac tgcacaattt
      541 gattggagaa ttcaaaccaa tttctcacaa tgttttagaa acaagggtct attatttcaa
      601 ctgcaaccta ctatagtcca ttgaagctgg aatagcccac tgagacttct aaaccactgc
      661 tggagaggag tttgtttaga gtttctttca tttccctaaa aaatcaaaaa gagagaacca
      721 gtctgatcct ctcttattta tagatggtgc tcactcaaat gttaaaggag ctatttctta
      781 gagataaagg aatttgaata cagctactgc cgcaattgct gctacgatag gtgctactac
      841 tggtacccaa gaataccacc attttgaatc gcctttatgc tcaccaagaa ctgattttgg
      901 aaggaaagca tgaaggagac gtggtcccaa gtcacgggct gggttcaagg caggtcctgt
      961 aggtcctcca agtgatgtta ccaaagccat aacgaggaat ccaagtgcca agtgagccac
     1021 agaaagtcct gaagcagtgt gtggagccac ctgtgcttta atagccaagt cagaaaaatc
     1081 aactgtttgt cctgcttcta ttgccttttg tttcatgaat tgaagcactt cagcaccaaa
     1141 gaagttttta gtcaaaccaa gagctgcaaa gaacaaaaca aatgaaccaa caaactcatt
     1201 aatcaaacca ttgacagttg ctgcatagcg actttctttt gtaccatggt caatacttga
     1261 aatagttgag aaagttccca agatgttatt tgggttttca gttttcaagt agaatggacg
     1321 gtatgttgcc acaactaagg cttggccaaa gatagctccc aagacttgcg cgataatata
     1381 aggtaccact tgtgcccaag ggaaaagacc gctaactgca agccctagag tgaaagcagg
     1441 gttgatgtga ttcccagata cgttaccaaa catcaaggct gggatcataa cccccatacc
     1501 ataaccaaca gcgatgacga tccagccact ttggtgacct ttcgtacctt taagttcaac
     1561 gttggcaact gcaccattcc caagaatgat caaaatggca gttcccaaaa attcagtggc
     1621 atacttcagt gcccatgtga aatccatttg ctagattctc cttaaaattt tttagatatt
     1681 ccttatttta tcaattttta ccctatttag caactgattt ctggaaatat ttttaaaaaa
     1741 ataggattca tagtttccca gttcaacgga cttgtaagcg tttttattct tcacgaaaga
     1801 cctcgttctc aaaaccagga aaaaagccca catctgtgag cttttcctgg ttcctagatt
     1861 ctaaaatcta ttatttttca tcttcttttt tcttgaagaa tcctaatcct agactagcta
     1921 acaaggtcat gataccagca ctagccaagg tagcattagc ttctgtacct gtgtttggca
     1981 attcctctct cttacctgtc tcataagtcg gaacttctgg gtctggattc actggagttt
     2041 cagtttttgg agtacctggg tctggagttg gtttatctgg tgttgataaa cggtcatacc
     2101 ttaccgttat ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa
     2161 tatctggatc tttgtacttg tcaatcttac cagatacaac ctcgtcccag tttcctgttg
     2221 tccattcacc gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg
     2281 ttacaggttg aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa
     2341 tgatacgcgt tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct
     2401 caacattctc acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg
     2461 agttgctacc aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt
     2521 tgttgttttc ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc
     2581 agcttttata acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt
     2641 tactgtagca gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc
     2701 gcttacaata ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata
     2761 ttttccgtca gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc
     2821 aatcagttgt tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt
     2881 atcatttttc aatgatagca aacgcccttg ttcatcaaca tagcgaactt tcacattttc
     2941 tgagattagt tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt
     3001 ccctttctct tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga
     3061 tggttccaca gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac
     3121 acggtgactt tgagtgttta ctactactct ttcattattc tctgaaaata cttgtacggt
     3181 ataagaaaca acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc
     3241 tagtttgcta tctccagagc ccacttcttt cctaatctta tcagatagtt ttttaccagt
     3301 cagtacattc gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa
     3361 ctcttcagaa ccagatctag cccaaccatt attaagggca tttgcttttg tatttgtatt
     3421 ctctctcaaa agtttggcga ttagaattat attcatcggc acttagagtt gctgctatat
     3481 ctgactcttg aataccaact tccttactac catttctagc ggcagtatat gtgtatttat
     3541 ttgtttctac ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga
     3601 gtcttcagta gtttatatgc tctgtcatca tctttagctt tagaagcagc tgagtttagc
     3661 caagttgggg tattaggagt atctttatca gcctgtttca agacattatt caagtcattt
     3721 gctagcctat tggttgtcct cactgtgaaa gttttcttcc agtctgaacc acttttatta
     3781 gacttagata tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta
     3841 gcatcttccg ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag
     3901 tttttttatt tacacgattt aatgtactat tttttatttt agtattaaga actccattaa
     3961 tacgattttt aaactctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat
     4021 tcaaaccttt cttatacaag tcttcattct aaacgatttc ggctacacgg tgaatggttt
     4081 gattgtatac cgtcttctct taaccagcag tatccttagt tttaatgact actcgatagg
     4141 ttcctttaga accgttatag tcatctagtt ttaaaaaagc attccaaaca ttcaaaaata
     4201 gttggaactt cccttaataa atccgtcact ttctttttca agatagccca agcttgctca
     4261 ataggattca aatccggtga ataaggtggt agaggtaaga aaaagtgttt atcttggatg
     4321 cagagttcat ccaaaatgtt cttgggatga aaactagcat tgcccatgac aataacatga
     4381 ggtgtcttca aagcaggtag gagttgcgtt ttgaaccact ccacaaagaa atcgcttgtc
     4441 atgcttttct tgtaaatcat gggagctata aactctccgt ctacttgtcc tgcaacaatt
     4501 gaagttcgct caaaacgacg tccgctaatc tttttataga ctttctcccc tctaggagcc
     4561 cgtgcataag gacgatagag gtagcggtcg attcctgttt catcaatata tacgattggt
     4621 aaatctttta ggttatccaa aatatcaaga aactcagcga ctttctctgg ctcttgttcc
     4681 ttaaagctcg tcatcttttt ttaaagtgac cttaatatac tttaaagctg cccatacgga
     4741 gggcagagca caatcaaaat gtgccgcaat ttcccgtaaa aaagcatctg gatgagcctc
     4801 tacaaaggct ttcaattcct ctaaaggaat ctttcggttt ttgacgactc gctttttcct
     4861 ctctatgtgt ccttgttcac atctttcttt tcccacgtga agagagttct gacgccaaca
     4921 ccaaaaaact tggctgcctc gacatggctg tgcccctctt tgatgtaatc taatgctcgc
     4981 tgtttaaaat cagtactata tgccatagct ttattataat atgcttgttt aaaactaagc
     5041 aactatatca atgttttgtt attagaagac ttactttttt tactgaaatc gaatttttcc
     5101 taacctcaac atcatataac cccaaaattc aatctgacct ggtttgaaga gatgttcgaa
     5161 gcagataagg ttttactaaa actaaaaaaa atgatataat caaactgatt aaatgtttta
     5221 aaaataaagg agaatttgaa tgtcttacca agaaaattac cagaaatggg ttgattttgt
     5281 ggagcttcct gactaccttc gtcaagattt ggaaaatatg gacgaaaaaa ctaaggaaga
     5341 tgccttctat acaaatcttg aatttggtac tgcaggtatg cgtggcttgg ttggtgctgg
     5401 tacaaaccgt atcaacatct acgttgttcg acaagctact gaaggattgg ctcgtttgat
     5461 tgagtcaaaa ggtggaaacg agaaagaacg cggtgtagca attgcctacg atagccgtca
     5521 cttctcacct gagtttgcct ttgaatctgc ggcagttctt gctaaacacg gcatcaaatc
     5581 ttacgtattt gaaagccttc gtccgactcc agaactatca tttgcagttc gtcatctcaa
     5641 ctgtttcgca ggtatcatgg tcacagccag ccacaaccct gctccattta acggttacaa
     5701 ggtttacggt gaagacggtg gacaaatgcc tccacacgat gcggacgctt tgactactta
     5761 tatccgtgca atcgaaaacc catttgcagt tgaagttgct gatgtggaaa ctgaaaaagc
     5821 ttctggcttg attgaagtta tcggcgaagc tgttgacgta gaatacctta aagaggttaa
     5881 ggacgtaaac atcaacccag ccttgattga agaatttggt aaagacatga agattgtcta
     5941 cacaccactt catggtactg gtgaaatgtt ggctcgtcgt gctcttgccc aagcaggatt
     6001 tgactctgtt caagttgttg aagcgcaagc aactgctgac ccagacttct caactgtaac
     6061 atctccaaac ccagaaagcc aagcagcctt tgcccttgct gaagaacttg gtcgtcaagt
     6121 tggtgcagat gttcttgtcg caactgaccc agacgctgac cgtgttggtg ttgaagttct
     6181 tcaaaaagat ggtagctacc tcaacctttc aggtaaccaa atcggtgcta tcatggctaa
     6241 atacatcttg gaagctcaca aaaacgctgg aactcttcct gaaaatgccg ctctctgcaa
     6301 atctatcgtt tcaactgact tggtaacgaa gattgctgaa agctacggcg caactatgtt
     6361 caacgtcttg acaggtttca aatttatcgc tgaaaaaatc caagaattcg aagaaaaaca
     6421 caaccacact tacatgatgg gatttgaaga aagcttcggt tacttgatta aaccatttgt
     6481 acgtgataaa gatgccatcc aagccgttct tgtcgttgct gaacttgctg cctactaccg
     6541 ttctcgtggt ttgacacttg ctgacggtat cgaagaaatc tataaagaat atggctacta
     6601 cgcagaaaaa acaatctctg ttactctttc aggtgtcgat ggtgctgaac aaatcaaagc
     6661 gattatggct aaattccgca acaatgctcc aacagaatgg aacgcaacag ctatcactgt
     6721 cgtagaagac ttcaaggcac aaactgctac tgttgctgac ggtactgtta caaacttgac
     6781 aactcctcca agtgatgtgt tgaaatacac acttgctgac ggttcatgga ttgccgttcg
     6841 cccttcaggt acagaaccaa aaatcaagtt ctacattgca gttgtagggg aaaccaacga
     6901 agaatcacaa gctaagatta ctaacatcga agcagaaatc aatgcatttg taaaataaag
     6961 acctataaaa gatgagacca accaacctca tcttttttcg tatcaaatct aagcaatttt
     7021 agaaacttta tggcatacta gacttatcaa tgaaagcgag gtaatctcat ggaacaattt
     7081 ttagataaca tcaaagacct tgaagtcact acagttgtgc gtgcgcaaga agctcttgat
     7141 aaaaaagaaa ctgcaacctt ctttatcggt cgcaaaactt gcccttactg ccgtaaattt
     7201 gcaggtacat tgtcaggtgt cgtagctgaa accaaagctc acatttactt catcaatagt
     7261 gaagaaccaa gccaactcaa tgatttgcaa gcattccgct cacgttatgg aatcccaact
     7321 gtaccaggtt ttattcatat tacagatgga caaatcaacg tccgttgcga ctcttcaatg
     7381 tcagcacaag aaatcaaaga tttcgcagga ttgtaaaaaa tcagctaaca agtcttaaaa
     7441 tcacaaaaac gcataatgta aggtgcaaaa accttgatat tatgcgtttt attgttccta
     7501 aaacagttac atcagcattt cattacagaa cattttaatt ttggaagtca aatcaatttt
     7561 taacaatgtt ttagaaatca cagtgggcta ttccatattc aattatccag attcaatcgc
     7621 tattatcgtt ttcctagatt acaaaaaaaa ctacgttttg ctaatcaaaa cgtagtctca
     7681 gccactattt tatcttactg tccttctttt acttctttgg ttgctacatc ttctccaaac
     7741 catttttggc tgatttcttg gaacttgccg tccttgtaaa gactagaaaa agcttcattt
     7801 atcttcttaa ccaaggttgt atcttcctta cgggctccaa ccgcaaaagc ttctgtttct
     7861 agtccaactg taaagacatt ataatcgttt aaaacacctt ctgcttctaa ataatagttt
     7921 gcatagacac ggtcaatcaa tagaccatca attcgatcgt ttttcaaatc aatcaaggct
     7981 tcattaaagg tttggtattg attcgcttcc ttattagcga caatattctt caaaatttct
     8041 ggatttgctt caaagtccgc ataaccagat gaaccagctt gagctcctaa tgtctttcca
     8101 gtcatatcct ttgcagtcgt gataccagat gattttttcg taaccaatac ctgctcattc
     8161 ttcatatatg agttactgaa agccaccttt tcacggcgtt cgtctgtagc ggaatagcca
     8221 ttccaaatca gatcaatcgt tccttttgtc aattcagctt ctttcaaatc ccaatcaatc
     8281 ggttgccaat ttaccgtgat tccgtatttt tcaaaaacag ctgtagctaa atcaatatca
     8341 aatcctgcat aagaaccatc tttctgagca aatcccattg gaacaaaagt actatcaaat
     8401 ccaatagtaa tagacttgtt agactggtac tttgaccaat tatctccact agtttcgcta
     8461 gaatttttcc cacaagctac taagaacaaa gcagtcatca gactgactaa tacaagcatc
     8521 cattttttca tccatttttc ctcctattta ggttctactt tcaataatac atctgcgata
     8581 ttttcagcaa actgcaaatc atgggtaacc acaatctggg tcatcccaag ttccctattt
     8641 tgcaagatta gcttctccac ttccaaacgt aattctggat ccagggcaga agttggttca
     8701 tcgtagccaa tgatttctgg gtcaatcatc atagcacgcg ccaaagccac ccgctgcttt
     8761 tgcccaccag atagtgagaa aggataggcc tctgcgtgtc ctcctagtcc taactgttcc
     8821 aagagtccac tcgccttctt ctcagcctct tcctgcttca ttcccatggt cttcacaggc
     8881 gataaagtca aattttccag aactgataga tgaggaaata gttgaaaatc ttggaagaca
     8941 aatcctagta ggttgcgctt ctgcaattca tccagctcta aaggttgtcc attataaaag
     9001 atttgccctg aatcaatggt ttcaagaccc gcaagcatac gtaaaagagt cgtcttacct
     9061 ccaccagaag gtccaacgat agccaggatt tgcttttcag gaatacttag actgaaatta
     9121 gacaggattt gtttgtctcc aaagacttta ttgatatttc gtaattctaa catggcagcc
     9181 tcctatctat aataactata cttcttctca acttttttgg aaataattgt cacaatccca
     9241 atcaaaatca aataaatggc tcctgccaag aacataggaa ctagactagc atcgcggtta
     9301 gcagctgttc gactagccaa gataaggtct gaaattccga gagcatagac caaagaagta
     9361 tccttgacca aactcataac ttcattaaag acactaggaa gaacgatctt ggtcacttgg
     9421 ggcaagataa tatagcgcac tctgtcaaaa gggctaaact tcaagacctt ggcggcctca
     9481 tactgtcctc ttggaatagt gtcaattccc ccacggaaaa tttctgcaaa gtaagctgca
     9541 tagttgagaa caaaggcaat aatagctgca ggaaggcggt ctaaacgaat cccaatactt
     9601 gggagcacat aatagataaa aattagttgc aagagtaagg gggttcctcg cataacccag
     9661 atgtaaatgt taatcagata atggaggggc ttccaatgga cttgcaaggc aaaagcaatc
     9721 aaaacgccca agggaatcga aaatagcaag accagtgcaa agacctgtac agtcgtgctc
     9781 gcaccattca gtaaactcgg taatatctca aataaataag acatactgca cctcctaaaa
     9841 gtaattgttc ctattatagc atgaataaac aagattacca agtatttttg taaaaagatt
     9901 ctaccatata caaataaaaa ccgtagctat caaaagagat aaactacagt tctatatgtt
     9961 taaacattct tacaatctct caaacagttc ttgcatttgc acatcatctg gaaccagttt
    10021 taagtaagtg tgagcatgga cttttgcttc ttcaaaatgt cccaattcac gcaagagata
    10081 gatatagtgt tccagaaatt ctggattgtc cttcaaatct cctgtcaact cttgataatg
    10141 ctcataagca gtatccaaat cgtccatttc ttgataagaa cgagcaatca tccacttggt
    10201 caaaagattt tctggctcct cactctgcaa gtctagaata tcctcataac gctcctgctc
    10261 cagataaata gtggctaaac gaagcaagat ttcttctgta tcctcagcgt cttcttttgc
    10321 agcaagaaga taattttctg caccactagc atcatgcaat tcataagaaa attgtgaagc
    10381 agctagcaag aggcgagttt caaagggatt tttctctaat ccttgcttag cgatacgcag
    10441 ggcttcttga acttgatgtt ccttatgtaa agcctgactg tacccatact catagccttc
    10501 aaagtcagga gaaatggtat caagctgctt aaagtagagg gtggcttttt gatattcttc
    10561 ttgatcaaaa taaagactgg ccaactcaaa agctgttaag tcatcgtatt ctaactccag
    10621 ggctttttct aaaaactcag tagccgtttc aaatttccct aactgagcat aggcaaagcc
    10681 aattcgttga taggtggaaa tgcccgtttg ctcataaatc gagcgattat ctaactgggc
    10741 ataggcttga atagccgctt ggtaattttc caactcacta tccaactctg ccaaacccaa
    10801 catcaagaga gaatcctctg agtaggtcaa ggcctccaat aatttctcac gtgccacatc
    10861 tgtcaaacct tccagctggt aaaggtctgc cttcaaaacc aaagacgaga cataccagtc
    10921 actgtcagct tggatttcct caagataggt aaaggcttct tctatttgac catcctcgct
    10981 agcaattgca gctagattaa gatgaacctc tggaaaatcc tctacaattt tcaggtaaat
    11041 ttccttggcc tgaggataga aaccaatccc ttcaagataa gttgccaact catacagaag
    11101 atcacttgaa tcattttcta aagctttggc gaaataatac tcagccttag ttaaatcttg
    11161 ctcctccaaa gcctgtaaca tctgttgact attgttcact cttgacttcc tcaccctcta
    11221 attcatatag accactgact accttatacc attcgaaaat ggctgaaatg acaaccttag
    11281 cagaggcata aaccggaata ccaagtaaaa ctccccagat accaaacata gatcctgaag
    11341 ttaacaaaac aaagagaaca ttaatagggt ggatgtttaa ttgacttccc aaaatcaatg
    11401 gagagacaaa acggccttca atagtttgtt ctacgataaa gacaatcact actttcaaaa
    11461 gcatgactgg accagcaatc aaacccaata ctagagcagg aagcatggct agaaagctac
    11521 caagataagg gaccagattt aaaataccag cagtaacccc cagcgtaacc gcatagcgta
    11581 gaccaataat cttgaagaag atgataaata ttactgctac aataatagcc actgtcactt
    11641 gccctcgaac atagttggac aactgttgat tcacatctga taaaacttgt ccaacaggtt
    11701 ccttcaattt tcttggaatg aattgggtca aatagttacg caagcctttc ccatcacgca
    11761 agagataaaa gagcatgaaa ggaacgataa tcaaggcaac aatcacttga gaagctccac
    11821 taataaaggc actcacccag ttgactgcct gagatgaaac cttacttgcc aaaactgtag
    11881 cctggctaga aaaattggtc aaaacttgct ctaattgagg tctgaaatca tctggcaggt
    11941 gctgggctac caatccatta acaatcctat ctatatcttc taagtaaaca ggaacgtttc
    12001 ttgcaaaggt caaaacctga cgttgcagat ttggaatggc gactgccaag ccccaaatga
    12061 taaagagagc gatgataaca aagacaatag tgatagctat aacacgatta accttatgct
    12121 tctccatcca atcaacaata ggattcaaca aataatataa caaaccagac aaaatgactg
    12181 gcaacatcac aactgctaaa aaatctaaaa caggtgaaaa tagaaaacta atcttactta
    12241 aaataaaaag attcaatccc aataataagg ttactaaaaa taccgtaatt gccttgttat
    12301 ctaaaaacca cttgaaaaac caagataggc taaaatgttt ctctttttgc tccataaata
    12361 cttcctttct attgttctct cattatacca tttttgaaac aaaataactc ttttttaaag
    12421 tgcttacatc taattgaatg tctttaattt gcttgttttt gtgatataat agtcttatct
    12481 ttacacagag gtatagtaat gaaagaaact gtttattttg gaacttatac acgtcgtact
    12541 tctcaaggga tttacaaggc agactttgat acagaaactg gtcagctttc aaatctagaa
    12601 ctttttgcag ctgagccaag tccaacctac cttgcctttg accagcacca acatttatac
    12661 actgttggta gccaagacga taagggggga attgcagcct atcaaactga cgggactgtg
    12721 ttaaatcatg ttgttgaaga aggagctccc cactgttatg ttgctgtcga tgaaaagcgt
    12781 gatttggttt acgcagccaa ctatcacaag ggacaagtcc ttgtttataa acgccaggaa
    12841 gatggtagtc ttctacttag tgatatggat caacacagtg gccaaggtcc acatgaaaat
    12901 caagcttccc cccatgttca ctatacagat ttaacacctg accactatct agtgacctgc
    12961 gacttgggaa ctgaccaagt catcacctat gacctcgatc aagaaggaaa attatctaag
    13021 ctctatacct atcacagcaa gccaggagca ggctcacgcc atatcatttt ccataaccac
    13081 tataaaatcg cttatctcat ttgtgaactc aatagtacta tcgaagtttt aatctacgat
    13141 ggcgttggcg aatttgtacg tatgcaggtt atttcaactt taccagaagc ttacgaaggc
    13201 tttaatggaa ccgctgctat tcatctctct aaagacggta aatacctcta cgcttctaac
    13261 cgtggccatg attctatcgc agtatatacc atccttgcgg acggtagctt agagttatta
    13321 gaaatcgttc caacgcatgg tcagactcca cgtgattttg atttgacacc cgaccaaaaa
    13381 tttctcattg ttgtccatca agactctgac aatgcaactg tctttaaacg taattgtgac
    13441 aatggtcgtc tagcagaact ctccaacgaa ttccatgttc ccgaagcagt ctgcatccgt
    13501 tttgctcctt aaaacaccat aaaaaatggc tctataatat ttgtagtggg taaatcccct
    13561 atggatatta tggagcctat ttttgtgtag aaaaaaagtc ccataagatc tataatgaaa
    13621 agcgatcaaa caactcatta gaaagattca tatggaacaa ttacatttta tcacaaaact
    13681 actcgatatc aaagacacaa atatccaaat tatagatgtc gtcaataggg attcacacaa
    13741 agaaatcatc gccaaactgg actacgacgc accatcttgc cctgagtgcg gaaaccaatt
    13801 gaagaaatat gactttcaaa aaccttctaa aattccttat cttgaaacga ctggtatgcc
    13861 tactagaatt ctccttagaa aacgccgttt caagtgctat cactgttcaa aaatgatggt
    13921 cgctgaaact tctatcgtca agaagaatca ccaaatccct cgtatcatca accaaaaaat
    13981 tgcgcaaaag ttgattgaga agatttctat gaccgatatt gctcatcagc tggccatttc
    14041 aacttcaact gttattcgta agctcaatga ttttcacttt aaacatgatt tttcttgtct
    14101 tcctgagatt atgtcttggg atgagtatgc ttttacaaag ggaaagatga gcttcattgc
    14161 gcaagatttt aacaatctca atatcatcac tgttcttgag ggtagaacac aagctatcat
    14221 tcgaaatcac tttcttca
//
LOCUS       DAVKBK010000041        14215 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVKBK010000041 DAVKBK010000000
VERSION     DAVKBK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.041"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            69..866
                     /locus_tag="VWX69_001435"
     CDS             69..866
                     /locus_tag="VWX69_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU9192760.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1014..1136
                     /locus_tag="VWX69_001436"
     CDS             1014..1136
                     /locus_tag="VWX69_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEU9192761.1"
                     /translation="MTCDFKSETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1158..2198
                     /locus_tag="VWX69_001437"
     CDS             1158..2198
                     /locus_tag="VWX69_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEU9192762.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWMASGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDHLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2369..3643
                     /locus_tag="VWX69_001438"
     CDS             2369..3643
                     /locus_tag="VWX69_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU9192763.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELCLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3653..4531
                     /gene="truB"
                     /locus_tag="VWX69_001439"
     CDS             3653..4531
                     /gene="truB"
                     /locus_tag="VWX69_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU9192764.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4772..5074
                     /locus_tag="VWX69_001440"
     CDS             4772..5074
                     /locus_tag="VWX69_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9192765.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5182..5820
                     /gene="udk"
                     /locus_tag="VWX69_001441"
     CDS             5182..5820
                     /gene="udk"
                     /locus_tag="VWX69_001441"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU9192766.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5948..7288
                     /locus_tag="VWX69_001442"
     CDS             5948..7288
                     /locus_tag="VWX69_001442"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU9192767.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7266..7478
                     /locus_tag="VWX69_001443"
     CDS             7266..7478
                     /locus_tag="VWX69_001443"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU9192768.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7475..8350
                     /locus_tag="VWX69_001444"
     CDS             7475..8350
                     /locus_tag="VWX69_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU9192769.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8343..9158
                     /locus_tag="VWX69_001445"
     CDS             8343..9158
                     /locus_tag="VWX69_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU9192770.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            9151..9582
                     /locus_tag="VWX69_001446"
     CDS             9151..9582
                     /locus_tag="VWX69_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9192771.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9589..11256
                     /gene="recN"
                     /locus_tag="VWX69_001447"
     CDS             9589..11256
                     /gene="recN"
                     /locus_tag="VWX69_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU9192772.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11258..11986
                     /locus_tag="VWX69_001448"
     CDS             11258..11986
                     /locus_tag="VWX69_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU9192773.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12065..13888
                     /gene="lepA"
                     /locus_tag="VWX69_001449"
     CDS             12065..13888
                     /gene="lepA"
                     /locus_tag="VWX69_001449"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU9192774.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13969..>14215)
                     /locus_tag="VWX69_001450"
     CDS             complement(13969..>14215)
                     /locus_tag="VWX69_001450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192775.1"
                     /translation="SKHSFEVVDETDEVSSKHGFEVVDETDEVSSKHGFEVVDETDEV
                     SSKHGFEIVDETDEVSNHTYGKATLTWFEEIFEEYKN"
BASE COUNT         4195 a         2598 c         3376 g         4046 t
ORIGIN      
        1 cagaaaacgc ttcctaaaac ctaaagtttg tgatataatt atcaagaaaa aagatttagg
       61 agtttattat ggtttcttca gaatttatct caaagattga atttgcttgc aataagaaag
      121 aaagtcttta tagtcaaagc aaatttaagt atgcgattcg ttcgatgttc gcaggtgcat
      181 ttttaacctt cagtactgct gcaggtgcag ttggggctga cttgattaat aaaattgcac
      241 caggtagtgg acgcttcctc tttccattcg tttttgcttg gggcttggcc tacattgttt
      301 ttttgaatgc cgagttggtc acttcaaaca tgatgttctt gactgctggt agtttcttaa
      361 aaaaaatctc ttggagaaaa acagctgaga ttttactata ctgtaccttg ttcaacctta
      421 tcggagcctt gatagcaggg tggggctttg ctcattcggc agcctatgcg aatctgatac
      481 acgatagttt catctcaggt gttgttgaga tgaagttagg ccgctcaaat gaattggtct
      541 tgcttgaggc gattttggca aatattttcg taaatattgc gattctgtca tttattttgg
      601 tcaaagatgg tggtgccaaa ctttggcttg tgttgtcagc tatttacatg tttgtattct
      661 taacaaacga gcacattgcg gcgaactttg cttctttcgc gattgtgaaa ttcagtgttg
      721 ctgcggattc aattgccaac ttcggtgttg gaaatatgct tcgccactgg ggtgtgactt
      781 tcatcggaaa ctttatcgga ggaggcctct tgatgggtct tccatatgcc ttcctcaata
      841 aaaacgaaga tacttatgta gattaagaaa atgagcacga ttgagtcgtg cttttttcat
      901 tttcaaaata aggtaatagc tatttcttat atcaaaatat agaaaactga tatttgtaaa
      961 ctataactca aggtgctaca atatccttaa taaaatgata tggaggtcac cttatgactt
     1021 gtgattttaa atctgaaact ctacaactac atgctggtca agttgtggct ccagctacta
     1081 agtctcgtgc agtgccgatt tatcaaacaa cattttttgt ttttgatgac acgtaggaag
     1141 gtgccgatct gtttgccttg aggaaaccag ggaacattta tactcgtatc accaatccta
     1201 caacagctgc ccttgaaggt ggtgttgaag cgctagcaac agcatcaggt atgactgcag
     1261 tgacttatac gattttggcg cttgcccatg ctggtgacca tgtagtggct gcttcgacta
     1321 tttacggtgg aaccttcaat cttttgaaag aaccccttcc tcgttatggt atcacaacaa
     1381 cctttgtcga tgttgataat ttggaggaag tagaagcagc tatcaaagac aataccaagc
     1441 ttgtcttgat tgaaaccttg ggtaactcct tgattaatat tccagacctg gaaaaactgg
     1501 cagagattgc tcataaacat caaatcccac ttgtgtcaga caatactttt gcaatacctt
     1561 atttgattaa cgtcttctct catggcgttg acattgccat tcactctgcg actaagttta
     1621 tcggtgggca tggtacaact attggaggaa taattgtcga tagtggtcgt tttgactgga
     1681 tggcttcagg gaaattccct caatttgttg acgagggttc aagctgccac aatttgagct
     1741 atactcgtga tgtgggtgca gtagccttta ttatagctgt tcgagttcaa ttgcttcgtg
     1801 atacaggtgc agccttgtca ccattcaatg ctttcctctt gctacaaaga cttgaaacct
     1861 cttcacttcg tgtggaacgc catgtacaaa atgctgagac aattgttgat tttcttgtca
     1921 accatcctaa ggtagaaaag gtaaattatc caaaacttgc agatagtcct tatcatgcct
     1981 tggctgagaa atacttgcca aaagatgtcg gttcaatctt taccttccat gtcaaaggtg
     2041 gcgaggaaga agcacgcaag gtcattgatc atttagaaat cttttctgac cttgcaaacg
     2101 cggcagatgc taaatcgctt gttgtccatc cagcaacaac cactcacggt caattgtcag
     2161 aaaaagacct agaagcagca ggtgtcacac caaactaaat tcgtttgtca atcggtcttg
     2221 aaaatgtaga agatttgatt gaagacttgc gcttggcctt ggaaaaaatt taaagtaaaa
     2281 gaagataaac agtgggcttc gactcactgt ttttgatttt ccctcaggca tgatataatg
     2341 gttaaagaag tctagaaaga ggaacgatat gaacgaaatc aaatgtccca actgtgggga
     2401 agtctttaca gtaaatgaga gtcagtatgc cgaactcttg tcccaagtga gaacggcaga
     2461 gtttgataag gaactacacg ataggatgaa gcaggaactg gccttggctg agcaaaaggc
     2521 catgaatgag caacagacta aactggctca gaaggatcaa gaaattgcgc aattacagag
     2581 tcagatccaa aactttgata cagaaaaaga attggccaag aaagaggttg aacagacaag
     2641 ccatgaggct ctcttggcta aggacaagga agtacagctc ttagaaaatc agttggctac
     2701 cttgcgtttg gagcatgaaa atcaactgca aaagaccctt tctgacctag aaaaagaacg
     2761 ggatcaggtt aaaaaccaac tacttttgca ggaaaaggaa aatgaattat gtttggcttc
     2821 tgttaagcaa aactacgaag cccagctcaa ggcagctagt gaacaagtcg agttttataa
     2881 ggattttaag gctcaacaat ctacaaaagc gattggggaa agcctagaac agtatgcaga
     2941 gagtgagttt aacaaggttc gtagtttcgc ctttccaaat gcttactttg agaaggataa
     3001 caaggtctct tcgcgtgggt ctaaagggga ctttatcttc cgtgagtgtg atgaaaatgg
     3061 agttgaaatc atttctatca tgtttgagat gaaaaacgaa gcagacggaa cagagaagaa
     3121 gcacaagaat gcagattttt acaaggaatt ggacaaggac cgtcgggaga agaactgtga
     3181 gtatgccgtt ttggtgacca tgcttgaggc cgataatgac tactttaaca cagggattgt
     3241 tgacgtcagc cacgagtatg aaaaaatgta tgttgttcgt cctcaattct ttatccagtt
     3301 gattggtctc ttacgtaatg cggcgctaaa ttccctaaaa tacaagcagg agttggcctt
     3361 ggttcgcgag caaaatattg acattacgca ttttgaggaa gacttggatg cctttaagct
     3421 agcttttgct aagaactata attcagcttc gactaacttt ggaaaagcta ttgatgaaat
     3481 cgacaaggcc atcaaacgca tggaagaggt taagaaattc ctgactacat ctgaaaacca
     3541 actccgtcta gctaacaaca aattggaaga tgtctctgtt aaaaaattga cccggaaaaa
     3601 tccaacaatg aaagcgaagt tcgaagcact gaagggggag tagaaagcaa aaatgaacgg
     3661 tattatcaac ttaaaaaaag aagcaggaat gacctcgcat gatgcggttt ttaaactgcg
     3721 taagattttg ggaaccaaga aaattggtca tggtggaacc ttggatccgg atgtggtggg
     3781 tgttttgccg attgcggttg gcaaggcgac acgcatggtc gagtttatgc aggacgaggg
     3841 taagatctat gagggggaaa ttactctggg ttattccacg acgactgagg atgctagtgg
     3901 ggaagtgatc gcagaaaccc ctgttttgtc tcccttggat gaaaagcttg ttgatgaagc
     3961 gattgctagc ttgactgggc ctattaccca gattccccct atgtattcgg cagttaaggt
     4021 taatggtcgc aagctctatg agtatgcgcg tgctggtcag gaagtggagc gtccagaacg
     4081 tcaggtgatc atttatcaat ttgagcgaac aagtccgatt tcttatgatg gccaacttgc
     4141 ccgattcact tttcgtgtaa aatgcagtaa agggacttac atccgtactt tgtcagttga
     4201 tttgggtgaa aagcttggtt atgcggctca tatgtcccat ttgactcgta ctagtgctgc
     4261 tggcttacaa ttagaagacg ctctttcctt ggaggaaatt gctgaaaaag tagaggctgg
     4321 gcaattagat tttctccatc ctttagagat tgggacaggt gaccttgtca aagttttcct
     4381 aactccagaa gaggctacag aagttcgctt tggtcgtttt attgagctag accaaacgga
     4441 caaagaactg gctgcctttg aagatgataa attgttagcc attctagaaa aacggggcaa
     4501 tctctataag ccaaggaagg tttttagcta gatcgtttag gaataaaaat cgggtgatag
     4561 ataacaattg cttgataaaa ccccatacta atagtagaat ggttttggga attataatat
     4621 tccaattgtt gcgagttgta ggtactcaaa taatctatat agaaatttag aggtgtgaaa
     4681 tgaagcaatt taaaattctt tcagataaat atttagagtc cattacaggt tctggtggga
     4741 acttaggccc aggatttggt gtgataattc catgatgcga aatgagtttc gagaaagggt
     4801 ggagcaactt cttcaacaaa aagaaataaa tgaaaatagt gagttgagtc acctgtttcg
     4861 tcttgctata caaaatttag acagaaatga aaaataccaa tcggtcatgg ccaatttgag
     4921 tcaagggttg tcactttacc tcatgacgca tcattaccag gcacctaagt ctgtcattga
     4981 ttttggttta tggattgcca aagctcctag ccaggaaaga gggagactgg ctttcttgca
     5041 gatgcttgct caaaccttac agggctttcg ttaaaactgt cgaacatcag agggaagact
     5101 ctggtgtttt ttgctgatga gactataaat tttgtaaaaa atgtgataga atagacgacg
     5161 gataaaataa cggaggatag catgcaaaat agaccaatca ttattggagt gacaggtggt
     5221 tctggtggtg gtaaaaccag tgtttcaaga gccattttat cgcattttcc tgatgaaaag
     5281 atttccatga ttgagcatga ttcatactac aaggatcagt ctcatttgac ctttgaagag
     5341 cgtgtcaaaa ccaactatga ccatcctttt gcctttgata cagacttgat gatcgagcag
     5401 attaaggaat tgttggcagg gcgtccggtg gacatcccga cctacgacta tacagagcat
     5461 acacggagta gcaagaccta tcgtcaggag cctcaagatg tctttatcgt tgagggcatt
     5521 ttggtcttgg aggacaagcg tctgcgcgat ttgatggata tcaagatttt tgtggatacg
     5581 gatgacgatg tgcgtattat tcgtcgtatc aagcgtgata tggaggaacg tggccgtagc
     5641 cttgatagcg ttattaacca gtacttaggt gtggtcaaac caatgtacca ccagtttatc
     5701 gagtcaacta agcgttatgc tgatatcgtc attcctgaag gggttagcaa taccgtggct
     5761 atcgacctgt tgacgaccaa gattgcaaag attttggaag aagctcgaaa cagcaaataa
     5821 tcacatgtgg aggccttgcc tcctttttct atttttccct cataatggta cataaatgga
     5881 gatttttagg catatttttg gtataataat acccataaaa gagcaagtaa atgaatagta
     5941 ggtggagatg gaaaagtatt tatcggtaac aactttgacc aaatatctga aaatgaaatt
     6001 cgataaagac ccatacttgg aacgggtcta tttaactggt caagtttcca actttcgtaa
     6061 acgacctact caccaatatt tctccctaaa ggatgaccat gcagttattc aagcgaccat
     6121 ctggtctggg atttatcaga aattagggtt tgacctggaa gaaggaatga agatcaatgt
     6181 gattgggcgt gtacaggtct atgaaccaag tggtagctac tccatcatca ttgaaaaagc
     6241 tgagcctgat ggggttgggg cgcttgcgat tcagtttgaa caacttaaga aaaaattgac
     6301 agaagaaggc ctgtttcaag aacgcttcaa gcaagctcta ccccaatttt ctaagagaat
     6361 tggggtagta accagccgta gtggagccgt tattcgagat attatcacga ccgtcagcag
     6421 gcgattccca ggtgttgaca tccttcttta tcctaccaag gttcaaggtg aaggggctgc
     6481 ggaggaaatt gctagaaata ttgcgcgtgc taatcaacgg gacgatttgg atttgctcat
     6541 tattggtcgt ggaggtggtt ctattgagga tctctgggcc tttaacgaag aaattgtggt
     6601 acgagctatt tttgaatctc gtttgccagt tatctctagt gtggggcatg agacggatgt
     6661 gaccttggca gattttgtgg cagatcgacg cgctgcaacg ccaacagcgg cggctgaact
     6721 ggcaacacct gtgaccaagt tggatgtatt aactcatttg caaaatcagg aaaaacggat
     6781 ggcaacggca gtccgaaatg ttctatctaa gaaacaagag gctttgaaaa aatgcagtca
     6841 gtctgttatc tttagacaac ctgagcgctt gtatgacggt tatttgcaac gcttggacca
     6901 actgcaactg cgtttgaaac aaagtttgcg aactcggatt tctgataaca aacaattagt
     6961 tcaagcaaga actcatcaat tagtacaatt atcacctgtt accaaaatcc aacgctatca
     7021 agaccgttta ggacagttgg acaagctctt aggtagccaa atggcgttag tttatgacgc
     7081 caaggttgct gaggccaagc gactttcgga agctttgctc atgttggata ctagccgaat
     7141 cgtggcgcgt ggttatgcta ttgtcaaaaa agaagagtcc attgtagatt cggttgagag
     7201 tttgaagaaa aaagaccaag taacgctttt gatgcgagat ggtcaagtag aattagaggt
     7261 taaagatgtc aaaacaaaag aaatttgagg aaaatctagc agaactggaa accattgtcc
     7321 aaagtttgga aaatggtgaa attgctctgg aagatgcgat tactgccttt caaaagggca
     7381 tggtcttgtc aaaagagctc caagctacgc tggacaaggc tgaaaagacc ttggtcaagg
     7441 tcatgcaaga agacggaaca gaaagtgatt ttgaatgaaa aagcaagaaa aattagctct
     7501 tgtcgagtcg gctttggaag atttttatgg agaccagcag tttgcctcta gtttacggga
     7561 gtctgttctc tattctattc atgctggtgg caagcgtatt cggccttttc tcttgttaga
     7621 agttctggaa gccttgcagg ttaccatcaa acctgctcac gcgcaggtag ctactgcctt
     7681 ggagatgatt catacaggga gcttgattca cgatgacctt cctgctatgg atgatgacga
     7741 ttatcgaaga gggcggttaa ccaatcacaa gaaattcggt gaagctatgg ccattttggc
     7801 tggagatgcc ttattcttag acccatatgc cttgattgcg caggcagatt tgccaagtca
     7861 gattaaggtg gacttgattg ccaacttatc ccttgcttca ggtagtctgg gtatggtggc
     7921 agggcaagtt ttggatatgg agggcgaaca ccagcacttg tctttggaag aacttcagat
     7981 tattcatgcc aataagactg ggaagttact agcctatccc ttccaagcgg cagctattat
     8041 agctgaattg tcacctgaaa tgcaggtgaa gctgaaaact gtgggtgaat tgattggact
     8101 tgcttttcaa gtcagagatg atgtactgga tgtgacagct agttttgagg aaatcggcaa
     8161 gacacctcaa aaggatctgc aggcagaaaa atcaacctat cctgccctgt tgggcttgga
     8221 agagtccatt gccttttgta accaaaccct ggatcaagct aatgaaaaat tagaagaaat
     8281 tgcccagcag cttccctttg aaacagaatc gattgtaagt gtagtagaaa gtttgagaat
     8341 caatggctaa ggaaagagtg gatgtactag cttataaaca ggggttgttt gaaacgagag
     8401 agcaggccaa gcgaggtgta atggctggcc tagtcgtagc agtccttaat ggagaacggt
     8461 ttgacaagcc aggagagaaa attccagatg acaccgaatt aaaactcaag ggagagaaac
     8521 tcaagtatgt cagccgtggt ggtttgaaac tggaaaaggc cttgcaggtc tttgatttgt
     8581 cggtggatgg cgcgactacg attgatatcg gggcctctac tggaggtttt accgatgtca
     8641 tgctacagaa tagtgccaag ttggtctttg cagtcgatgt tggtaccaat cagttggctt
     8701 ggaaattacg ccaagaccca cgagttgtta gcatggagca gttcaatttc cgctatgctg
     8761 aaaagactga tttcgagcag gagccgagct ttgccagtat tgatgtgagt ttcatttccc
     8821 ttagtctgat tttgccagcc ttgcatcgtg tcttggctga tcaaggtcag gtggtagcac
     8881 ttgtcaaacc tcagtttgag gcaggacgtg agcagattgg gaaaaatgga attattcgag
     8941 atgctaagat tcatcagaat gtccttgaat ctgtaacagc tatggcagta gaggcaggtt
     9001 tttcagtcct tggcttggac ttttctccca tccaaggtgg acatggaaat attgaatttt
     9061 tagcgtattt gaaaaaagaa aagtcagcaa gcaatcagat ttttgctgag attaaagaag
     9121 cagtagagag ggcgcatagt caatttaaaa atgaataaaa aagagagact tgaaaaaatt
     9181 agaagattgg tgacagatta tcaaatcggc acgcaagaag aaattgtaga acatttgaaa
     9241 gaagcaggta tcactgccac tcaggcgacg gtatcccgag atatcaaaga gttaggtatt
     9301 gtcaaaattc ctttgagaga caacacctat gtctacgaat taccaaaatc aatcgtaaaa
     9361 agtctgcaac tggctgaaga caatatcgaa tcggctgaat tgatggataa gatgatcaat
     9421 ctccaagtta ttccaggaaa tacggctttt gtaaaagctc agttaatcga tacttttgca
     9481 gacaagattt ttagttgttt gactgatgat agctcgattt tagtcattgc cagaagtgga
     9541 agtctagcag aggaaatctt tgaacaagta aaaaattggt aggtctatat gttacttgaa
     9601 atttcgataa aaaactttgc cattattgag gctatttccc tcaattttga aaaggggatg
     9661 actgtcctga ctggtgaaac gggtgcaggg aagtcgatta tcattgatgc catgaatatg
     9721 atgttgggag ctcgtgcgac gacagatgtt attcgtcatg gtgcaccaaa ggcagagatt
     9781 gaggggcttt tctcagttga gaatagtcgt cttttacagg aaatttttga tgagcaaggt
     9841 ttagaattag gtgatgaaat tatcatccgt cgggaaatct tgcaaaatgg tcgtagtatc
     9901 agccgtgtaa atggtcagat ggttaatctg tctgttttgc gagctattgg gcaacatctt
     9961 gtagatattc atggtcagca tgaccatgag gagttaatgc gtccccaact gcatatccag
    10021 atgttggatg aatttggtga tgccgctttt tgggacttga aagaaaccta tcaaacgagt
    10081 tttgatgcct atcggaaaat gcgcaagcag gttctggaag tcaagaaaaa ccaacaggaa
    10141 cacaaggaac gtatcgaaat gttggaattt caaatggcag agattgaggc agcaaacttg
    10201 caggctggag aagacttggc tctcaatcaa gagcgagata aactcctcaa ccacaaaaat
    10261 attgcggata cactgaccaa tgcctacagt atgttggaca atgaagattt ttcaagtctg
    10321 gccaatgttc gttcagctat gaatgacatg gaaagtgtcg aagagtatga tcctgaatac
    10381 cgtgaaattt caagctctct gtctgagacc tactatgttt tagaagacat tagcaaacgt
    10441 ttggaagcta tcattgagga ccttgatttt gatggcaatc gcctgatgca ggttgagaat
    10501 cgtttggacc tccttcatac tattactcgt aagtatggtg ggactgttga tgatgttttg
    10561 ctttattttg ccaagattac ggaagaatac aatctcttga caggcaataa tctttcgtct
    10621 gaggacatgg aagcagagct taagaagttg gaagtcaatc ttgtcaattt ggcaggtcaa
    10681 cttgcttctg ctcgtcataa tttggctcag caactcgaag ctgagattaa acaagaactg
    10741 caagatcttt atatggaaaa agcccagttt caggttcatt ttagtaaggg aaaattcagt
    10801 cgtgggggaa atgaaatggt tgagttttat atttcaacca accctggaga agactttaaa
    10861 cccttggtta aggttgcttc tggaggggaa ttatctcgtc tcatgttagc cattaagtct
    10921 gccttttcac gtaaagaagg caagactagc attgtctttg atgaggtgga tacgggagtt
    10981 tcaggtcgtg ttgctcaagc tattgctcag aaaattcata aaattggtca gcatggtcag
    11041 gttttggcta tctcccattt gccacaagta attgcgattg cagattatca attctttatt
    11101 gagaagatta gtaatgacca ttcaacggtt tcgactgttc gtctcttgac agtcgaagag
    11161 cgagtggagg aagttgccaa gatgttggca ggtgatgatg tgacagaagc agccctgacg
    11221 caagccagag aattgttgag aaacagggag aaataagatg acagattatt atgtaattgg
    11281 agatgttcac ggaaaagctg ggatgctgga agaccttctt aaaacctggg atggtcagac
    11341 ccagttgctc tttctaggtg atttgattga cagaggtgag gatagtcacc gtgttcttga
    11401 aatggtcaag gacttggtgg acaatcaagg ggctatctgt ttgtctggaa accacgagta
    11461 tatgtttttg acttggctag atgacccaga agaaagttat gaccattatc gtcgcaatgg
    11521 tggagataca accattaact ctatcctagg tcgtcccttg gatgcaccag ttgatggagt
    11581 agaagatgcc aagcgggttg ccgctgaagc gtcagacttg gtcgaattca ttcgtcaaat
    11641 gccatttgta gtagagacag acaagtatat atttgttcac gcaggtattg atttgacttt
    11701 ggacgactgg catgaaacaa cagattataa aaaagtatgg cttagaaaac cattccacgg
    11761 agctgaaaat catactggaa aaaccattgt cttcggtcat acaccggtct atggtttgtt
    11821 acagcaagaa cgcggtacat ctgagctttg gactacagaa gatggcaaga ttggaatgga
    11881 tggaggagct gtttatggtg gtgtccttca cgggattgtc tttacagacc aaggaatgac
    11941 agaacaccac tttatcgaaa atgacggctt tgtcgctgaa gattagtact cctagcaggg
    12001 tatggtcttg tcaaaatatc aaaaacaatt tataataaat agataccctg aaaggaagag
    12061 aatcatgaac ttagaagaat tgaaaaaacg acaggggaag atccgtaact tctctattat
    12121 cgcccatatt gaccacggga aatcaactct agcagaccgc attttggaaa aaacagagac
    12181 ggtttcaagt cgtgaaatgc aggcccagct tttggatagc atggatctag agcgggaacg
    12241 tggaattact attaagttga atgccatcga gttgaattac actgcaaaag atggggaaac
    12301 ttatattttc cacttgattg acacaccagg gcacgttgac tttacctatg aagtttcacg
    12361 ttcgctagct gcctgtgagg gtgctatttt ggtggtcgat gcggctcaag gaattgaggc
    12421 tcaaactctt gccaacgttt atctggcttt ggataatgat ttggaaatca tgcctatcat
    12481 taataaaatt gacctgccgg ctgcagatcc ggagagcgtg cgtacagaga ttgaagatgt
    12541 gattggtttg gatgccagtg aagcagtttt ggcttctgcc aaggctggta ttgggattga
    12601 agaaatcctc gagcaaattg tagaaaaagt accagcacca acgggtgatg tgacggcgcc
    12661 acttaaggcc ttgattttcg actctgttta cgatgcttac cgtggggtta tcctccaagt
    12721 gcgtgtcatg gacggagtgg tcaaacctgg tgataagatt cagctcatga gcaatagtaa
    12781 gacctttgat gtggccgaag tcggtatttt tacaccaaaa gcggttggtc gtgatttcct
    12841 tgcgactggt gatgttggtt acattgcggc gtctatcaag acggttcagg atactcgtgt
    12901 gggtgatacc gttaccttgg caaccaatcc tgcggcagaa ccattacatg gttataagca
    12961 gatgaatcct atggtctttg cgggtctcta cccaatcgaa tcaaacaagt acaatgacct
    13021 gcgtgaagcg cttgaaaaat tgcaactgaa tgatgctagt cttcagtttg aaccagaaac
    13081 atctcaggca cttggatttg gtttccgttg tggatttctt ggacttctcc atatggatgt
    13141 tatccaggaa cgtttagagc gtgagttcaa tattgatctc atcatgacag ctccgtctgt
    13201 tatttacaaa gttaatttga ccgacggtga gtctatggat gtgtctaacc catctgagtt
    13261 tccagaccca actaagattg cgaccattga agagccttat gtcaaggcgc aaatcatggt
    13321 accacaggag ttcgtcggag cagtaatgga gctagctcag cgtaagcgtg gggactttgt
    13381 gactatggac tatattgatg ataaccgtgt caatgttatc tatcaaattc ctcttgctga
    13441 aatcgtcttt gacttctttg ataaacttaa gtcttcgaca cgtggttatg caagttttga
    13501 ctacgaattg tcagaatatc gcccatctaa gctagtgaaa atggatatcc ttctcaacgg
    13561 agacaaggtg gatgccctca gctttatcgt tcataaggac tttgcttatg aacgtgggaa
    13621 actcatcgtt gataagctca agaaaatcat ccctcgccaa caatttgagg ttccaatcca
    13681 agcggctatt ggacacaaga ttgtcgctcg tactgatatc aaggcccttc gtaagaacgt
    13741 acttgctaaa tgttatggtg gtgacgtttc tcgtaagcgt aaactccttg aaaaacaaaa
    13801 agctggtaag aaacgcatga aatccatcgg atcagttgaa gttccgcaag aagccttcct
    13861 cagcgtcttg agtatggatg aagaataagt tatcagaaat gcctttcctt gttcacagga
    13921 aatttatata agaatcaata gtaaagcagg cttagatggt ctgctttttt agtttttata
    13981 ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta ccgtatgtat ggttactgac
    14041 ttcgtcagtt tcatctacaa tctcaaaacc atgttttgag ctgacttcgt cagtttcatc
    14101 tacaacctca aaaccatgtt ttgagctgac ttcgtcagtt tcatctacaa cctcaaaacc
    14161 atgttttgag ctgacttcgt cagtttcatc tacaacctca aaactgtgtt ttgag
//
LOCUS       DAVKBK010000042        14194 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVKBK010000042 DAVKBK010000000
VERSION     DAVKBK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.042"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(258..1865)
                     /locus_tag="VWX69_001451"
     CDS             complement(258..1865)
                     /locus_tag="VWX69_001451"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU9192776.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDTEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2255..2842)
                     /locus_tag="VWX69_001452"
     CDS             complement(2255..2842)
                     /locus_tag="VWX69_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU9192777.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(2970..3419)
                     /locus_tag="VWX69_001453"
     CDS             complement(2970..3419)
                     /locus_tag="VWX69_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192778.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3424..3813)
                     /locus_tag="VWX69_001454"
     CDS             complement(3424..3813)
                     /locus_tag="VWX69_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU9192779.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3841..4467)
                     /locus_tag="VWX69_001455"
     CDS             complement(3841..4467)
                     /locus_tag="VWX69_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9192780.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4481..5044)
                     /locus_tag="VWX69_001456"
     CDS             complement(4481..5044)
                     /locus_tag="VWX69_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9192781.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5209..5443)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5497..6000)
                     /locus_tag="VWX69_001457"
     CDS             complement(5497..6000)
                     /locus_tag="VWX69_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU9192782.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6193..7023)
                     /locus_tag="VWX69_001458"
     CDS             complement(6193..7023)
                     /locus_tag="VWX69_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9192783.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7008..8690)
                     /locus_tag="VWX69_001459"
     CDS             complement(7008..8690)
                     /locus_tag="VWX69_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192784.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LISDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8792..9049)
                     /locus_tag="VWX69_001460"
     CDS             complement(8792..9049)
                     /locus_tag="VWX69_001460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192785.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9056..9604)
                     /locus_tag="VWX69_001461"
     CDS             complement(9056..9604)
                     /locus_tag="VWX69_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU9192786.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9619..10467)
                     /locus_tag="VWX69_001462"
     CDS             complement(9619..10467)
                     /locus_tag="VWX69_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU9192787.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10655..12004
                     /gene="trkA"
                     /locus_tag="VWX69_001463"
     CDS             10655..12004
                     /gene="trkA"
                     /locus_tag="VWX69_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU9192788.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            12008..13447
                     /locus_tag="VWX69_001464"
     CDS             12008..13447
                     /locus_tag="VWX69_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9192789.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13572..13829)
                     /locus_tag="VWX69_001465"
     CDS             complement(13572..13829)
                     /locus_tag="VWX69_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEU9192790.1"
                     /translation="MNEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILAPQVRSYYRE
                     MKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
BASE COUNT         4169 a         3229 c         2615 g         4181 t
ORIGIN      
        1 tcacatctta tttcaattca tgatacaatc cagttcctaa aactttgcta gaaattaatt
       61 tggctttccg aattaatttg ttcagatttt atttcatttc aatatactga taaatccatt
      121 cactagcaca gggcaagagg gagtcgctat tgatttcaac ggtagcaggt acatacagag
      181 gactcctacc tcagatatac tgcaatatca tcgtatgcaa aaaacctctg agatttttct
      241 caaaggttct gattttgcta attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag
      301 agttcttctg gtcggtttgg acggcttgac agttcagggt gatactgaca agctacaaag
      361 aatttatttt caggaatttc cacgatttct accaaacgat tgtctggaga aactcctgaa
      421 aagacaaaac ctgctgcctc aaactgctca cggaaggcat tattaaactc ataacggtga
      481 cggtgacggc gttgcaccac ttcttgattg tgataagcag cagcagcctt agagccacgt
      541 ttcaacttag acggataaag tcccaaacga agggttccac ccatatcctc aatatcaatc
      601 tgatcacgca tgatatcaat gatagggtat tttgtttctg gtgcaagctc tgcagaattg
      661 gcaccttcaa gacctaaaac gtgacgagca aactcgatac atgtcaactg cattcccaag
      721 cagactccca acattggaac atcattttca cgcgcatagc ggatggcttg gattttccct
      781 tctgtaccac gttgaccaaa accacctggt acgatgatcc cgtccgcatc agacaagagt
      841 tctgctacat tctctgctgt cacatcattg gcattgaccc aattgatttt aacttctgta
      901 tcattgacat agccagagtg tttcaaggct tcgaccactg agatataggc atcttgcaac
      961 tccacatact taccaacaag ggaaatctta acttgtttct tgaggttcat gaccttgtcc
     1021 accatggctg accattctgt catagccgct gctggtgcgt ctaatttcaa atgatcacaa
     1081 acaatttggt ccatcccttg tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca
     1141 tccaacgatt cgataacggc ttctggtgcc acatcacaga actgggccag tttattttta
     1201 attccttgac cagctggctc ttctgtacga ataaccaaca tatttggttg gattcccaag
     1261 ccacgcaatt ctttgacaga gtgttgggtt ggtttggttt tcatttcacc agcagccttg
     1321 aggtaaggaa gcaaggttgt atggatatac atgacattat ccgcacccac atctgccttc
     1381 atctgacgaa gagcctctag gaatggcaag gactcgatat ctcctactgt tccaccaacc
     1441 tctgtgataa tgacatcaga gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa
     1501 gcatctgtga tatgaggaat gacttgaaca gttgccccaa ggtattctcc acggcgttct
     1561 ttacgaagaa cttcactgta aattttccca gttgtcacgt tggaatattt gttgagattg
     1621 atatcgataa aacgttcata gtgacccaag tccaaatctg tctcagctcc gtcatctgtc
     1681 acaaaaactt ccccgtgctg gtaaggactc atggttcccg gatcaatatt gatataaggg
     1741 tcaaactttt gaatggttac tttgagacca cgatttttca agagacggcc tagactcgct
     1801 gccacaatcc ctttcccaat agacgatacc acaccaccag ttacaaaaat atatttcgta
     1861 gacatagatt cctctttcta aaatgctcaa ggtcttgtta actacgaggg gatatagaaa
     1921 acaagaccct actaataaga ataatctggg acgactgcac cagattcaca actaatactc
     1981 ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt
     2041 tgtcagtctt atctacaacc tcaaaacagt gttttgagca gcctacggct agtttcctag
     2101 cttgctcttt gattttcatt gagtataaaa tacaagaaga taacttcttg aaaaaacaaa
     2161 aatagctccc taagaactag ggagccccga cctctaaaag aggtgcccaa acaatatgat
     2221 acctaaaaat aggataattg tcaatagcta actcttattc ctcgctggtt tcagcgtcgt
     2281 catctgaaaa ctcgtcgtcg tcttcgttga gatccacatc ttctcccaag tcatctggag
     2341 cgatttcgtt gatttctgca tcataagctt ccacttcatt tttttcatca tctggatttt
     2401 catcatcgta tgaaagagct ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg
     2461 cattgtagtc aatggcatct gaatcaccat ccataaaggc attgacacgt tttttcttag
     2521 cttttggtgc tacttcatcg tcgtcatttt cttcaagagc gatgatttct tcgtcgattt
     2581 cgtccacacc ataccatgaa cgaagacccc atttgttgtc cccaagtgag atgaagctac
     2641 cgtcaaagtt caactctgtg tagaacagag gcaaagcttc gcggatatcg ctgtttgatg
     2701 ttccaaggta gttttgaatt tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac
     2761 cacgaagttc taatatagca cgcgctacct caatcataga tagttcactt ttttcttgcc
     2821 cagcaaatac ttctaattcc aaagcgtttc tcctcattta tactactatc gccagagcga
     2881 acagactctg acctcatttt atcatttact ctttatttta cgataatttt gcggaatagt
     2941 caaaggttaa gggggagaaa gtggcaggat tagactaatt ccaatataaa actccttcct
     3001 ttttctgttg ctccattttc cacaaatcca agcgacttga aacacctcct agaagcatga
     3061 ttgtaggtgt agatttcctt gactctcaat tctttccatc cttttactcg agccaattca
     3121 atcaaagcac ttagaatctt ttttccaagt cctcgatgtt ggtaagcgga attcccaatc
     3181 acaatgggga gattatcctg agatagtgta atatccccaa ttggaaacca ttctcccttc
     3241 tccttgactt caatccaaaa aagctcacca tgccgatcca aataggaata catggcttcc
     3301 aaggtcgctt gactgtaagg aagcttcacc ccatctacga ggtaaaccaa gttcacatcc
     3361 tgataccaag caaaagcttc ctcacaatga ttgaccttat aataaggaac aaaacacaat
     3421 gcactacctt ttcaacaaaa gagttgctgc ttgattaaaa ccatcacacc agttatacca
     3481 ttttgcttca tacccatctt gagctaggat acgatcttct aaatcaaaaa cagagtaaat
     3541 ctttctttcc tcgcaagctt gcgcatagag atgatatagt tcatcaccac catctctatc
     3601 ccactcagca gaaatcgtat cccgatctgc caataaagtc tgataagccc tgtgatgccc
     3661 atctgtaatc agcaaacaat ctccaaaggc aagaatactg attggatcga cttggattgt
     3721 ttctgccgac tggtaaagca tctgaatatc ttgcaacttc ttttctgata aatatagttg
     3781 agtcggatga agatctgcta tgttgacttt catttctttc tcctcaaggg aattcgatac
     3841 tcacttctgt ttgcctttaa atcgccattg gaagcggagc ttgtcataga agggaaactc
     3901 gataaacagg actcccaagc ccacacagag actggcaagg acgtctgatg ggtaatgaac
     3961 tcccagatag actcttgata ccagcacact gactaggtag aggccaagga cgatttgtac
     4021 gatttttctc cagactggat ctttaatccg ctgactaaga ataacaatca aagtacctac
     4081 catcaaggtt acagccagag aatgcccact tgggaaggaa aatcccttct cctccaccag
     4141 atgtaagata tctggccgtg ggcgctggta gatattttta aaggtcacga ttaaaagacc
     4201 tgccaaagcc agatttccca gcatgaagaa actttctatc ttccatcgct tacgataaaa
     4261 gacaaaagct gtaatgacaa cccaagtgat aatcactggg atatcaatca gacgtgtgag
     4321 ggctcgaaaa agaatagtca aataatctgg taagtctcct cgaatggcag tctgaatcga
     4381 ttggtcaaaa ttgaccagcg tttcagggta aaatttgacc atgtagccaa gaataacgaa
     4441 aagtaaaagg gcaaaactgc ccttcattaa aaatgtttgt ttatctctca taatgtttta
     4501 aggttggttt caagagaaca tacaacaacc agaatgaaac ggaaaagata acaccttcaa
     4561 tcaagttaaa aggtaatacc atggtcatta ggtagttgga aagtcccaaa atttttccaa
     4621 tatcaaagtt agcaaactta gcgtacaaag gaacagcata aacatagttg agaaccaaca
     4681 tggccaaggt taaaccaata gttccagcta gagagcctag taggaaacga agggttgtcc
     4741 gttccttttt ccaaatcaaa gcaaatacga tgacaaaaac tcccaaagct acgatattca
     4801 tcggcaaacc aatgtaagta ttcactcctt ggctgttaag aagcaacttc aagagtgagc
     4861 gaagcaagag cactcctaga gcagcaggca aatccatgac caccagaccc acaaggactg
     4921 gcaagatact aaattcgatc ttgaggaaag atgccgctgg taaaagcgga aaatcaaagt
     4981 acatcagcac aaatgagatg gctgatagaa ttgcaatggt cgaaagtcga cgtgtgtttg
     5041 tcataacagg ttcctccaat tttctataaa atcagaagaa gttggaaagg attcctctat
     5101 ctattctcac tttttatatc ccaaaagttc cctcttactc tattaaagaa aaacaaagca
     5161 agtggttaca atccggctat aaatctatca aaacagacaa agctattctt tcgtcttctc
     5221 ccatccagac tatactgtcg gttgtggaat ctcaccacat cagcttgcgc tcgcggactt
     5281 ctttaaaggg aaagaaatag agatttttct tttagactag gcgacaagct gtaggcataa
     5341 cttctggtta ggcaaagctt gtcaacaaag tataaaagga aaagatcatt tcctagttaa
     5401 agtcaccgcc ggtcgggaat cacaccctgc cctgaagact cttttatcat aacaaaaaac
     5461 gcttgcaagc gcaagcattt tgttcatttt cattttttat ttcaatttat ccacttcata
     5521 ggtatggacg agctcaagac ctgcaaagtt ctgctggcga agagcctcat agacaatcat
     5581 gcagacggta ttagacacat tgagactgcg gacatgttca tcattcatgg gaatacggag
     5641 agccttctca ggatgttctc gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa
     5701 gagaaaataa tggtcctcgt cagtcgataa atccacctca gaatagattt tttccgcgaa
     5761 tttcgaaatc agatagagtt ttcccttcat ctgagatatg aaatcttcta aactctcgta
     5821 aaaataaatc tctagcttat cccagtaatc caatccagcc cgcttcatct tgcggtcatc
     5881 aataggaaag cccataggct tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg
     5941 cgcgatattg cctgtatttt gtggaatttg aggttcaaat aatacaatgt gatttgtcat
     6001 gacttgcttc ctttcaccat tgcaaaaaaa tagccacact gcccggagtc aagctcagca
     6061 aacagcgtgg ttaaggcatc gttaacttac ctcacaacag gtttgaagta aatcagcgaa
     6121 actactttct tagtataaca ctttcagaat cattgtcaat agaaatgact tgattttttc
     6181 aattttttca agctatttcc aagggttgta aaatcgtccc tgattctgca agataagtag
     6241 taaactaact actaaaaaca aggttgccaa gagcaaggta atatagtctc cttttttcaa
     6301 ggcctgataa ctataccatg tgcgtttttt ctctttccca aagcggcgaa gctccatggc
     6361 agtcgcaatg gtatcaatgc gttctagcga gctaaaaatc aagggcgtaa taatgagcag
     6421 attgcctttg attcgttgca taagagaagc tttcttggat aattccatcc cacgcgcctc
     6481 ctgagacatc ttgatagtaa agaattcttc ctgcaaatct ggaatatagc gcaaggtcag
     6541 gctgacagaa taagcaatct tatagggcac accaatttga tttaaactgg aagcaaactg
     6601 actaggatgg gttgtcatca aaaagataat agccagagga atggtgcaaa gatacttaat
     6661 ggccaaattt agcagataaa agagctcctg gctggttaga gtgtagacac cgattccctg
     6721 ccaaatcaca cttctctctc cataaagtcc aaccccatac tcgggagaaa agagatagac
     6781 catcaaaacg tttaaaacgg caaataccgt cgcaaaaacg gctacaaagg aaacatcttt
     6841 aaagcgaatt tctgataaat agaggagaaa gactgaaaag atggcaatca gcaagagcat
     6901 tctggtatca tagctaatca tggccgccaa tgataccaga atgaaaaaga gaagtttccc
     6961 agctcctgac aagcgatgaa tcacagtatc tctatgctgg taaccgatta atttagcttg
     7021 catccctctc tcctttcttt gtaaaatgcc gttaaatcca gtggatccac atctagtttc
     7081 ttagccaagt taaagatgga ggtttctttt agattggctt ttactaacag ctcaggatcg
     7141 ctcaacagac tggctggaac agtatcggca atcaattctc catccaccat gacaaggacc
     7201 cggtctgaat aatccagcat caattgcata tcatgggtaa tcatgacaat ggtatgccct
     7261 ttttgatgta actcttcgag aaattccata atctcagtat agttcttctg atcttgacct
     7321 gcagtcggtt catctaggag aataatttca gctcctaaga ccaaaattga agcaatggtg
     7381 acacgttttt tctgaccaaa tgacagggca gaaataggcc aattacggaa ttcataaagt
     7441 ccacagattt tcaaggtttc atagactctc gtttcaattt ccttctcatc cacacctcgc
     7501 aaacggagcc ctagagccac ctcatcaaaa atcatattgg ttgaaatcat ttgattagga
     7561 ttttgtagca catagcctac tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc
     7621 tgtttttccc aaagatagcg tccttccgtc tgaataaagc tacttatagc cttggctaga
     7681 gttgatttcc ctgctccatt ttttccgaca atagcaatct tttcaccctt tttaatatct
     7741 aaatgtaggg attttaaaat cggtctatca tcataagaga aagacacgtc ctctaattta
     7801 aagagtgact gcaattctgg agtttctttt gccagttcat tctgcagctg aacctgacct
     7861 tttgagatag acatgttatc cagattcgct aactgttctt ccttgactaa gtccacacct
     7921 aattgacgga gagtcgttag ataaaggggt tctcgaattc cattttgagt caataaatca
     7981 gtcgcaagca actggtcagg gctcccatta aaaaggatac gaccatcgct tatcaagaca
     8041 atccgatcca cagggcgatg cagaacatcc tccaaacggt gctcgataat cagagtcgtc
     8101 gtcccctctt ccttatgaat ctggtcaatc aattcgataa tatcctgacc tgacttggga
     8161 tctagattgg cgagtggctc atcaaacaag agaatcggac tttcatcaat caagacacca
     8221 gccagactga ctcgctgctt ttgtccacct gacaaatcct gaggacgctg atccagtaaa
     8281 ggaagaaggt ccagcttttc agcccattta taaacacgac ctttcatctc atctagggct
     8341 gtcacatcat tttccagagc aaacgccaaa tcttctgcca cagacaagcc aataaactgc
     8401 ccatctgtat cctgcaaaac tgtgctaacc agatgagact tatcatagat gctcatatca
     8461 aaggctactt gaccctttat caaaaattct ccatatgtct gacccttgta aatattggga
     8521 ataatcccat tcaaacactg acccaaggta gatttacctg acccagatgg tccaacaatt
     8581 aagactttct ctcccttgta aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt
     8641 gtttcatacc ggaaagagaa atccttccac tcaattatag cttctttcat cttactctct
     8701 tcattcgctt cttagacttc tattttatca taaatcaagc ccttcttgca gtctcttctc
     8761 ttaaaatctt agcgccaaaa agattcctat cctagcttac ttgcctaact aatctataaa
     8821 catcgaaaaa gactagttgc ccagccttcc ccatcatttt atactcttcg aaaatctctt
     8881 caaaccacgt cagcttcgcc ttgccgtagg tatggttact gacttcgtca gtttcatcta
     8941 caacctcaaa accatgtttt gagctgactt cgtcagttct atccacaatc tcaaaacact
     9001 gttttgagca acctgcggct aacttcctag tttgctcttt gattttcatt gagtattagt
     9061 cctttttcaa acttcctgca cgagtttggg ttcctgcata ggcaagtaag agaagagttc
     9121 ctgcaatagc tacagataca ccattggcaa ttcccgcaac aatcccttgt gcaaatactt
     9181 tttctgccgc ttcttgataa atcacaacat ctccaagtgg tgccaagaca ccccaaacaa
     9241 gggcatttgc aagtagttga atgaggttaa aaataagaat atctttccag tcaaaaacac
     9301 cattgatcac tcgaacgtac tttctaaaaa gtcccacaac tagaccaaag agtccgctag
     9361 cgataatcca agtccaccat agaccataac cagcaagaga gtccttgatt gcatgaccaa
     9421 tcaacccgac aagcaaaccg ataatcggtc caaaaataat agaaagtagc gcttgtaccg
     9481 catactgaag ctggatgctt gtatttggaa caggggttgg aatgttgatc atcccgatga
     9541 cgacaaagag ggcagcgcca attccgacag caacaacttg tttaattgta aatttgattt
     9601 ccatactatt ctcctatttt atccttctat tttctttatt tcaatggtcc aagatgaacc
     9661 gacacctaca ttataggcct tggcaaagga accttggttg atagccaaac ctaaacgata
     9721 gagagagttg atgtaaagga tgggttgccc aattctcaca tctgcaaatg atttgccata
     9781 gacaacctga ttttgataga ccagcatatc agcatgatag atggtcactt caaaacgatc
     9841 accaaattct ggttccagct tgtaaaattc ttcccgtgtg atagaggtcc aaagcgaacc
     9901 gaaacgcaca tccagaatat caatggctcc cttcaccaga tgatcttcta tgatggtcgc
     9961 tacgactgga agctctacaa tctgttccac actgagctct ggccctactt cctcaaaagt
    10021 aatgtgacca ctggccagtt tagcaccagt ataggcatag acatcacgac cgtggaaggt
    10081 ataagaatgc tctgtgtttt gacgcctatt ggccacctca gaaatctcac gaatggctac
    10141 aatgccaacg tgtttcttga taaaggaaag cgtcccatta tctggcgtga caatgtattg
    10201 attttttgca gtcttggcaa ctacactctt acgtttcgaa ccgacacctg gatcgacaac
    10261 cgatacaaac gtcgttccct caggccagta atccaccgtc tgaaagagac gatagctccc
    10321 ctcaaaaata ttataaggcg tgatatcgtg cgtcaagtga tggattttta aggttggaga
    10381 ctcttctaaa gccactccaa tcatagccga caccgcacca tcaaccagac caaagtctga
    10441 ttgtaatacc agtaaattat tgttcatttt atctccttgt atatccttta tcataccata
    10501 tttcagagaa agtcgctaat agctatttca attggttagg gtatagtttt accttatagc
    10561 gaattttcac taaaagctct tgttattagc tagtaggtgc attttttctt gaaaaagggt
    10621 atgatagtta catcatgaaa aagtaggttt tattatgaaa attatccttg tcggaggggg
    10681 aaaagttggt tttgccctct gtcgctcctt ggttgcagaa aagcatgatg ttttgctgat
    10741 tgagcaagac gaagctgttc tcaatcatat tgtcagtcgc tttgatatca ttggtatcct
    10801 tggtaacggg gccgattttg ccattcttga gcaagccagc gtccaagatt gtgatatctt
    10861 tatcgccctg actgagcacg atgaagtcaa catgattgca gcagttctag ccaagaaaat
    10921 gggagctaaa gaaactatcg ttcgggtgcg gaaccctgaa tattctaact cttatttcaa
    10981 ggaaaagaat attctcggtt tttctcttat cgttaatcct gagctcttgg ctgcccgcgc
    11041 tatcgcgaat atcattgact tccccaacgc cctgtctgtc gaacgctttg ctggtggacg
    11101 cgttagcctc atggaatttg tcgtcaagtc caccagcggt ctttgccaaa tgcccatttc
    11161 tgattttcgt aaaaaatttg gtaatgtcat tgtctgtgcg atagagaggg atcatcaaat
    11221 tatcattcca agcggtgaca tgactgtaca ggataaagat agaatctttg tcactggtaa
    11281 ccgtgtcgat atgatactct tccataatta ttttaaatca cgcgccgtga agagccttct
    11341 catcgttgga gcaggtagaa ttgcctatta tctacttggt attctcaaag atagtcgtat
    11401 cgatacaaaa gtcattgaaa tcaatcctga aatcgccagc ttctttagcg agaaattccc
    11461 aaatctctac atcgttcaag gagatggaac cgcaaaagat atcctgctgg aagaaagtgc
    11521 tcaacactat gatgccgttg cgactctaac aggagtcgat gaggaaaatc tgattacatc
    11581 tatgttcctt gacagggtag gtgtacagaa aaatattact aaggtcaatc gtaccagtct
    11641 cctcgagatt atcaatgcgc ctgatttttc aagtatcatc acacctaaaa gcatcgctgt
    11701 agatacgatt atgcacttta ttcgtggtcg agttaatgcc cagtattcag accttcaagc
    11761 catgcaccat ctagccaatg gccaaatcga aaccctgcaa ttccatatca aggaagccaa
    11821 taaaatgact gccaaacctc tttctcaact gaaattgaaa aaaggggttc ttattgcagc
    11881 cattattcga aagggcaaga ctattttccc aactggggag gatatgttgg aagttggaga
    11941 caagctccta gtaacaacct tgttgccaaa catcaccaag atttatgact tgattgcgag
    12001 gtaagaaatg aataaaagta tgattcgtta cctcctttca aagttacttt tgattgaagc
    12061 tgttctcctc ttggttcctg tggctatcgc tgtctattac cgtgaatcga gccaagtctt
    12121 tacagccctc ttttcgacca tagggattct cgtattgtta ggcggttcag ggagtttaca
    12181 gaagccaaaa aatcaacgga tttatgccaa ggagggagtc ttgatcgttg ccctctgttg
    12241 gatcctttgg tctttctttg gtggtctccc ctttgtcttt tctgggcaaa tccctagcct
    12301 tattgatgcc ttttttgaaa ttagttctgg gtttacaact actggagcaa gtattttgaa
    12361 cgacatttcg gttctcagcc gttccctcct cttctggcga agttttaccc acttgattgg
    12421 agggatggga gtgcttgttt ttgcacttgc tattatggac aatgccaaaa atagtcacct
    12481 agaagtaatg aaggctgagg ttcctggtcc tgtctttggt aaggttgtat ccaaattaaa
    12541 aaacactgcc cagatcctct atctccttta catagccctc ttttccctct ttgtcatcat
    12601 ctattatcta gccggtatgc ctctctacga tagttttgtc attgctatgg ggacagcggg
    12661 aactggagga tttaccgtct ataacgatgg aattgcccac tatggtagct cactgattac
    12721 ctatctggtt agtataggag ttttggtttt tggggtaaat ttcaatctct actactacct
    12781 tatgctccgt cgggttaagg ccttctttgg agatgaagag cttcgggctt acttggtcat
    12841 cgtgctggtt tctacaggct tgattagcct caatactctc tacctctacc cagggttttc
    12901 aaagagcttt gaaatgacct tcttccaggt ttccaacatc attacaacaa ctggttttgg
    12961 atatggagat attaccaact ggcccctctt ctcccagttt atcctccttt tcctcatggc
    13021 aatcggtggc tctgctggat caactgcagg tggactcaag attattcgag gcctcatcct
    13081 ttcaaaaatt gccaaaaacc aaattttgtc aatcctatcg ccccaccgtg ttttgaccct
    13141 ccatgttaat aaaatggtga ttgacaaaga tacccagcat aagattctca agtactttgt
    13201 catctatgct atgattttgc tagcgcttat ctttattgtc agcctagata gcaatgattt
    13261 tctggtcgtg accagcgctg tctttagctg tttcaataat atcgggccta ttctaggaac
    13321 cacttctagt ttctcaatct ttagtcccat ctcaaaaatt ctcctctcct ttgcaatgat
    13381 tgcagggcgc ttggagattt acccaatcct ccttctcttt atgaaaagaa cttggtctaa
    13441 gagataaaat acaaaatccc tctttttaca attgtgaaag agggattttt atattaaaaa
    13501 gggggaacgt ttttaaatcc aagcctgtct gtaagcaaag ttcttactca aataaaagat
    13561 ggaaaaactt actacacagc ttggtaatgc tccaatacaa attgtaaggc tttacttgga
    13621 ttctttgtta aatgaatata ttccattcct ctggtagcaa ctatctgaat acctaatctt
    13681 tctgcatcca ccttcatctc tctataataa ctccgaactt gtggagccag aataattaaa
    13741 tcataaacac ccataatatc ataatgagct ccgtacgctc ctgaattcgc aatcactcta
    13801 acttctgcta attgagcgcc ctcgttaatt gcattggcta attacgcact tgttccagac
    13861 cctgcacaaa gaaccagtac tttcaactcc ttacttttta ttacatctat ctcaccaggc
    13921 attatttcac ttgtatcctc ctctaaaata atatcatttg agcttgcaat atctacaacc
    13981 tgtagtagat atctcgtatt tagacaatat gaaaacaaga cgacttccat ataggaaacc
    14041 gccttctctc tatgttgagt gatttatatt aaaataactt ttcttctagc tgcattttat
    14101 tattataaaa acattcatca taaccctgaa cttaaataac gatttttatt caagatacat
    14161 actcctagaa taaactttat atgaaattct catt
//
LOCUS       DAVKBK010000043        14014 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVKBK010000043 DAVKBK010000000
VERSION     DAVKBK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.043"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(140..1108)
                     /locus_tag="VWX69_001466"
     CDS             complement(140..1108)
                     /locus_tag="VWX69_001466"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9192791.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVAVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1253..2036)
                     /locus_tag="VWX69_001467"
                     /pseudo
     CDS             complement(1253..2036)
                     /locus_tag="VWX69_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(2061..2558)
                     /locus_tag="VWX69_001468"
     CDS             complement(2061..2558)
                     /locus_tag="VWX69_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU9192792.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2631..3992)
                     /gene="radA"
                     /locus_tag="VWX69_001469"
     CDS             complement(2631..3992)
                     /gene="radA"
                     /locus_tag="VWX69_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU9192793.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINGAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4006..4521)
                     /locus_tag="VWX69_001470"
     CDS             complement(4006..4521)
                     /locus_tag="VWX69_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9192794.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4523..4966)
                     /locus_tag="VWX69_001471"
     CDS             complement(4523..4966)
                     /locus_tag="VWX69_001471"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU9192795.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            5271..5420
                     /locus_tag="VWX69_001472"
     CDS             5271..5420
                     /locus_tag="VWX69_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192796.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            5562..5741
                     /locus_tag="VWX69_001473"
     CDS             5562..5741
                     /locus_tag="VWX69_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192797.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(5961..6326)
                     /locus_tag="VWX69_001474"
                     /pseudo
     CDS             complement(5961..6326)
                     /locus_tag="VWX69_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            6346..6513
                     /locus_tag="VWX69_001475"
     CDS             6346..6513
                     /locus_tag="VWX69_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HEU9192798.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            complement(6668..6871)
                     /locus_tag="VWX69_001476"
     CDS             complement(6668..6871)
                     /locus_tag="VWX69_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192799.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(6894..7085)
                     /locus_tag="VWX69_001477"
     CDS             complement(6894..7085)
                     /locus_tag="VWX69_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9192800.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            7656..8024
                     /locus_tag="VWX69_001478"
     CDS             7656..8024
                     /locus_tag="VWX69_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9192801.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            8024..8257
                     /locus_tag="VWX69_001479"
     CDS             8024..8257
                     /locus_tag="VWX69_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192802.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            8257..8520
                     /locus_tag="VWX69_001480"
     CDS             8257..8520
                     /locus_tag="VWX69_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU9192803.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            8533..8913
                     /locus_tag="VWX69_001481"
     CDS             8533..8913
                     /locus_tag="VWX69_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEU9192804.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            8930..10000
                     /locus_tag="VWX69_001482"
     CDS             8930..10000
                     /locus_tag="VWX69_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HEU9192805.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            10055..11196
                     /locus_tag="VWX69_001483"
                     /pseudo
     CDS             10055..11196
                     /locus_tag="VWX69_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(11279..11372)
                     /gene="ffs"
                     /locus_tag="VWX69_001484"
     ncRNA           complement(11279..11372)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VWX69_001484"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(11405..11872)
                     /locus_tag="VWX69_001485"
     CDS             complement(11405..11872)
                     /locus_tag="VWX69_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU9192806.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(12073..13359)
                     /locus_tag="VWX69_001486"
     CDS             complement(12073..13359)
                     /locus_tag="VWX69_001486"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU9192807.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(13590..13826)
                     /locus_tag="VWX69_001487"
     CDS             complement(13590..13826)
                     /locus_tag="VWX69_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU9192808.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         4672 a         3121 c         2317 g         3904 t
ORIGIN      
        1 acttctgatg acgtatagtc atatttcttc tctttttatt atatcacagt tttaaatcta
       61 gctttactag attcaccgct actatccatt tattcggaaa aaagacgaaa aaacctgaga
      121 atcatctcag gcttggtcat taaatttttt tctcaatatc gaaaagtgga gaaagtggtc
      181 gtttttcatg aatacgtacg atagcatccc ctaggagatg agcgattgaa atctgctcaa
      241 tcttatcaat caaacgctct tctggcagat agatggtatc caaaacaacc aatttcttaa
      301 tagctgattt ttggatattg tccgtagcag gaccagaaag aactgggtgc gtacagcttg
      361 catagactgc aacagcacca gcttccgcaa gagcatctgc cgcatgacaa atcgttccag
      421 cggtatcaat catatcatca atcaagatac aagtcttgcc ttcaacctta ccgatgatgt
      481 tcataacttc actagtattc atcttatcaa cgctacgacg tttatcaata atagcgatag
      541 atgttttcaa aaattctgcc aacttacgag cacgagtcac ccctccatgg tccgggctga
      601 caaccacata gtcagaacca accataccac gccgctcaaa ataatctgca attagaggag
      661 cacccatcaa atgatccaca ggaatatcaa agaatccttg aatttgcgca gcatgcaagt
      721 cgatggtcaa taaacgatcc actccagcta cttcaagcat atttgcgaca agttttgaag
      781 tgattggctc acgcgctctc gcctttctat cctgacgtgc atacccatag taaggcatga
      841 caacattgac agactctgca ctcgcacgct tcaaagcatc taccataatc aaaatttcaa
      901 gcagattgtc atttacaggc gaactagttg attgtaagat aaagacgtgt ttcccacgga
      961 ttgattcttc aatgttgacc tgaatctctc catctgaaaa ttggcgaaca cttgatttcc
     1021 ccaactctat cccaatctcc tgcgccacac gttctgccaa ttctttatta gaagaaaggg
     1081 caaacagctt taaatcagaa aaagacatga tttcctccgg tatatatgta tcgcttgtgc
     1141 ttttcacaag attttccatc taccattgta gcgctttttg cactattttt caatcaaaaa
     1201 taaaagaagg gcaccatatt tgtacccttg catcattctt ttgaaaaata ttctaggtca
     1261 tcaactcatt gtgtttctca acaaagcaat aagcatgata ataaccatag agagcaatag
     1321 ccgtaaccac tggaatcgct aaaggcaact ctgtttccaa ctccacaaaa ggagagttaa
     1381 acaataagac cctgtttctt gccaaccttc tgtcctttat aggctctgta aagcaagtaa
     1441 acacctacta cagctagacc tgaaaaagtc cagtgagagg caattcctga gatgatacgc
     1501 tctaaaattc gcgaaatagt aaagtcaaag ccctctggca aatccgtacg aatataacca
     1561 atatcctcaa tcatttggaa tcccaaaccg gaggcaattc caagtaaaaa caaaaatttt
     1621 aattttcgca caggaatcaa agccaaaaca aaaacaagtg gcaataattt caagggttct
     1681 tctaccaaag gagccacaat agcactttca aaggcattta aaaatggact atctgggaaa
     1741 agaaccccca gtaaatcatg tatataagta ttagcaaaac tagacaacca gcctgaaagg
     1801 aacatccctc ccaataaaga cagaatcaaa accttctttg gcaattccca ttttttccca
     1861 atacggaaga gaaaataaag agccggaatc atgtaaaaga gagctagaaa gatagaaact
     1921 cccattagtc catattccgc acctgacctc gaaccgtccg tatagtagat ggtttcatac
     1981 tgtaaaccaa tacatagcaa taaaataaaa ataaataaaa tactgctttt cttcatacac
     2041 tttctttcta aatgaagtat ttataattct acgactgtca tacttcctgt atcaacattg
     2101 taaatagcac cagagataat gacatcgtct ggtattaggg gagactcgat aagcagttgc
     2161 atatcctcgc gtacactctc ttctatatct tggaagggca agaagtcctg gtctgacaca
     2221 tctacaccta attcctcttt taaatactcc tgaaaaggtt cattttcaaa ggtctgagca
     2281 ccacagtctg tatggtgcaa taccacaatc tctcttgtcc ccatttgttg ctgggaaata
     2341 actagcgaac gaatcatgtc ttcagtcact cgaccacctg cattccgcaa gatatgagca
     2401 tccccaagtg ccaagcccag agcttgcgca acgtgcaaac gtgagtccat acaggtcaca
     2461 atggctactc tggttttagg tttaagtggc agatttaact gcccatgtag ggcaacataa
     2521 gcctgattgg cttgcataaa ctgttcaaaa tacgacacga ttccctcctt gaaaatttga
     2581 tagtcaaata tttctcctat cttatcattt ttaagagaat ttgtcacgga ttatgcaaag
     2641 acctttttca agacttcctg aatcgttgtc acgccaatga cctgaatttc cttaggcaga
     2701 gtgattcctg tcaaggaatt ctgaggtaca taaatcttag taaagcccag tttagcagct
     2761 ccgttgatgc gttgctcaat acgattcacg cgccgaatct ctcctgtcaa gcccagttct
     2821 ccgacaaaac attcctgagg attagttggc ttgtctttgt agctcgaagc aatagcaact
     2881 gcaacagcca agtcaatggc aggttcatcc aatttaacac caccagcaga tttgagatag
     2941 gcatcctgat tttgcaagag aagccctgcc cgtttttcca aaacagccat aatcaagcta
     3001 gcacggttaa aatcaagtcc tgtcgtagta cgcttggcat ttccaaacat ggtcggtgtt
     3061 accaaagcct gaacctccgc caaaatcgga cgcgtccctt ccatggttac aacgatggag
     3121 gaaccagtcg ccccatccaa acgctcttct aggaaaactt gactcggatt gagtacctca
     3181 accaagccgc ccgactgcat ctcaaaaatc ccaatctcat tagtggaacc aaaacgattt
     3241 ttgaccgctc tcaaaatacg aaaggtgtgg tgacgctccc cttcaaagta aagcaccgta
     3301 tccaccatat gctccaacat acgaggccca gccaaggttc cttctttggt cacatgacct
     3361 acgataaaga tggcaatgtt attggtcttg gccaactgca tgagttcagc ggtcacttca
     3421 cgtacctgag aaacagaccc ctgcacccct gaaatctcag gagacatgat ggtctggatg
     3481 gaatcaataa tgagaaagtc tggctggata cgctccactt ctgcacgaac actctgcata
     3541 ttggtctctg catagagata aaactcacta tcaatatcac ctaagcgctc tgcacgtagt
     3601 ttaatctgct gggcagactc ctccccactg acatagagaa ctgtccccac ttgggacaac
     3661 tgggttgaga cttgtaggag aagagttgat ttcccaatcc caggatcccc accgatgagg
     3721 acgagacttc ctggtaccac tccgcctcca agcacacggt tgaattcctc catctccgtc
     3781 ttggttcgat tgacattgat ggaagtcacc tcagctagtt tcatgggctt ggttttctca
     3841 cctgtcaagg acacacgcgc attcttgacc tcggcaacct caacctcttc cacaaaagaa
     3901 gaccaagacc cacagttggg gcaacgtccc agatatttag gggaattata cccacaattt
     3961 tgacatacaa atgtcgcttt tttctttgcg atgacaaacc tctttctata tctctaactc
     4021 acactcaatc acttggcaaa aatcaatctt ctcatttggc acaaactggc gcatgagcat
     4081 tcgatgagca acaactacca cagtctgatg ttctcgatac ttagacatac attctagaaa
     4141 ccgagacttc atttccgtag ctgtctcata ttgaatagga ctattaggaa gcaactcccc
     4201 cttgttttct aaaaacagtc ttctagctgt ttcaaagttt tctattcctg ttttatagac
     4261 ctgccattca tgtaataaag gctctactct taaaggaaga cccgtagcac agaccacata
     4321 cgaagccgtt tctaaagctc ttgtgactgc agaagatacg attatttcag ctgacgagag
     4381 taaaggattt ttgctcaatt tctggacttg ctgccgtccc atctcagaca agggtgccaa
     4441 atctatccca aatcctatat aagaacgctc ctctaactca cggtaatctg gctccccatg
     4501 acgtacaaag ataatcttca ttctagtgcc ctgtcgatcc aaatccacca gttcgaacgc
     4561 catcagctgc atctccatct gcaattaaga aagtagcaaa aacagcctgg acaatacgtt
     4621 ccccaacttc aagaacaacc tcttgatctg tgatattctt catctgcgca aaaatatgcc
     4681 cttcatttcc aggatttcca taataatccc catcaatgac cccaactgag ttaattaaaa
     4741 ccaagccctt cttacgagga tttgaagaac gatcatagag gtagagaacc tcagtcggct
     4801 gcatataagc cttaacccct gtcggaacca agacaatctc tcctggcgca acaactgtac
     4861 gcacagcaac ctttaagtcg taaccagccg catgcgctgt ctcacgcttg ggcaataaat
     4921 tttcatctgt aaaactcgaa accaattcaa aaccacgaat tttcataatt ttctcttttc
     4981 tattatcatt tattctagat tattctatct tatttattcg gaaaaagcac gaaaaaaaga
     5041 gcacacaaca attataggcg atacgataat ttacactgtt tcacaatacg ttgaaattta
     5101 gagctttaaa gcgagggcaa agttgatttt ttacatcgtt ttacagaggt ttacgacact
     5161 tttgcccctt ttttgcccct ttgtttttca aaaaaacttc atcaaatcgc ttgactttca
     5221 cggtttaccg tgatataata taatcaagat aaggaaagga ggtgaggaag ttgaacaaag
     5281 aagattggct taggttactg gaaaaggcga tagataatat ccctgaaacg gtaactgcta
     5341 tagcaagtct ggtgactgca ataacggtcg caaggcaaaa caaaaagcgt aaaccgaaat
     5401 cccgtcaaag aaaaaggtga acgctaagag gttggggcga aagcccctca cacctctatt
     5461 ttatcaaatg aaaagaggaa aagcaatggt tagtgcaata gctattttta taattgcggt
     5521 caatgtatat atttatctaa aaaataaaaa ggacaaataa gatgagagaa gttattcaag
     5581 aattgttaga cagttcgatg tctacatctg ctatttccca aggtgctgga gttccatgga
     5641 ctactgtttc tgacctcaga aaaggaaaaa caagcatgga caaaatggca cttctcacag
     5701 cagaaaaact ttatgaattt gctacaactg ataagcagtg atttcggtca ctgtttttat
     5761 ttttgacaaa acaccgtttt tgacaataat caaaaaataa aaaggagcta ttattaacaa
     5821 aatggcgttt ttggcaataa taccctgcca ttcctcctcc ctattcttca agaaaacgct
     5881 tttttgaaga atcagagcaa ataaaaaacc gcaagcctga gcctgcggtg aaagaacaat
     5941 ttagaaagtt tcctttctat ttatttaact gtaatcaagc catctggctc tactgtgaac
     6001 tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt tccgtccgct
     6061 gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta gtaccaagtg
     6121 tccttgtact tgacccagcc tgtcttcatg gcaccttcta catcaaaata gtaccacttg
     6181 tcagcgattt tcttccagcc tgtggccatt tcgcctgatt ggtcaaagta gtaccaatta
     6241 ccgtctgtgt gcttcttcca gcggtctgaa agcatatagc ctgagccatc gaaataatac
     6301 cagataccgt tgattttctc aaacttatag aaaggaggag atagtatggc aaatactcca
     6361 ataaaacctg gaacagataa tcagaaacct ggtcgctatg tagaggtagg acctcgtggc
     6421 ggaaaagtta ctaatggtca taccgcaact atcggaaaag gtgatcggct ccctccgaca
     6481 tctgctaaag gcaacggttg gaaaaaagtc taatcttcgt ttgcgtacaa tcgttcaatg
     6541 gttgtacgct ttttccatac acaaaagcac attcccaaaa aatcaatttg aatccatgct
     6601 tcggcgtaat ctttcccatt gctggcatag tgagttatat aatggtgaat cattttattc
     6661 cttcctccta ttgagttact tgagaagtat catgaatggc ttcatagcta agacgcttaa
     6721 attcttctga gtctatctga aaattgatag gctttttttg taaacactca agaaaactag
     6781 tgtttcttaa aagtttttca actaactcag ggtctgcctt tacaaaggtg gactcttttt
     6841 gtccactata cggatatcgt tttggtctca ttttcctact cctcaaatct ttcctactca
     6901 atcccataat cttcaataac ctgaagaatg aaactgttcg ctcgtggacc tttagtcgtt
     6961 ccacttagaa tgtttgtcac ttcctgtcgt ttaaagccgt aagcaaccgc tagagttgct
     7021 tttttaatgc ctttctcttt caagaaagca ataactcttt cgcgaccgtt tgcgatatct
     7081 ggcatatttt ctcctttctt tttctttctt ctttttctgc tataatataa gcagaaagga
     7141 gttaacctta tgacttttaa agaatattta ctcaaagcaa gcaaacgcga catctacgat
     7201 gatggtaaag attttgagaa atcaatttca gattctcact aatcgagcgt gacttttttg
     7261 atatggcaat ctcagaaatt taccaccagc gctgactacc ttaatgactt tttcaaggtg
     7321 gtctttttct tgttctaaat ttttaagaat acttaccatc agcacgttcc tcctctttac
     7381 ttatttgtaa ataagagaca actaaaaatg taactatttt tctgcattat acttgacaac
     7441 ttacaccaaa tcggctaaaa ttaaagcata ataaaaacac caataaatct ataaataccg
     7501 ttcgccaaaa catttttata atttatttct tagttgtttt tttagttgtt tatcacttac
     7561 aaaaaacatt ttacaccttt tgggataatt agtcaacctt tttacaccaa atttgttaaa
     7621 tttttttgtg atgtcttaga aaggttgatt taacaatgtt tgagacattt gaaaaaataa
     7681 aagaattggc aaaaaagcgt ggaaaagctc ttggacaagt agaagaagac ttaggttatg
     7741 gtagaaatac actctataag ataaaaaatt ctacgccaaa cgctgaacgt atcgcagaaa
     7801 ttgctaatta tttcaacgta tccaccgact acctgctcgg acgaacagat aaccctgcta
     7861 tcgctgggag tgatgaattt gcccaagtaa acggacaaat catagactta cgcaaagcag
     7921 cagccaacac catgttattt gacgggaaac cactaaatga agatgatatc gacttcatta
     7981 catccgtcct atccgcccac ttcaaaagca aaggagaacg ctaatgacta tcactatcaa
     8041 cttcacagaa aaaaattcct acattacgga ctacctaaac aaacacggta tcgacacaac
     8101 gaccatggat tttgacgact tcatggcact catggaagat atcgaagacg cacgagcagc
     8161 cgaccaagcc tatatggagt atttagccga cccagctact tataccatgg atgaggtctt
     8221 ggatgaacta ggactaactc gagaggatat tgcttaatgt atcggctaga tattgataaa
     8281 aaagctctca agcaacttaa aaaactagat accccaacca gaaaacaaat cctatcctgg
     8341 cttgctaaaa acattgaaaa cacgaccaat ccacgacaac acggaaaagc actaaaagcc
     8401 aaccttgcag gttactggcg atacagagta gagaattacc gcatcatctg tgatatccaa
     8461 gacgataaac tagtcgtcct agccgtggaa atcgcccacc gcagagatgt ctataaataa
     8521 cgaaggagaa ctatgacact cgctaaactc tgcgaagaat atcaagtaga actttgtctc
     8581 ttcgacggtt caaactggca caatagcggt ttctacaatc cagacacaaa cgtgctcgct
     8641 attgaccaca acttgactcc tgaacaacaa atccaagtcg ccctacacga acttggacac
     8701 aaagaccaca cacgctcaga gcaccagaac gcccgtctac gctgtgaaaa cgaagctgat
     8761 aggaatatga tccatcatct cgtaaaagac gctctagaaa acttagacga ccccacagag
     8821 tttgattacc tcaaattcat gtcttactac aatctaaaaa ccatgacaaa tgaaatcatg
     8881 gttaaagaag agtatttagc attagtaaat taaaaaaagg agtatcaata tggaaattga
     8941 taaagtaaaa gccgatttaa aacaagtcgg caaacgtgta gcagacctca gccaaagcat
     9001 tacgaatgaa gaacaaacaa agaatgcctt cattatgccg ttcttccaag cgcttggata
     9061 tgatatcttc aatccacttg aatttgtccc ggaatttact gccgacgtgg gcattaaaaa
     9121 aggcgaaaaa gtcgactatg cgatcatttt ggatggcgag cctcaaatcc taattgaatg
     9181 taaatcaatt acagaaaacc ttactaagca cgactctcaa ctattcagat atttcgtaac
     9241 tactaaatca aaattcggta tcttgacaaa tggtagagaa tataaattct ttactgattt
     9301 agatgagcca aataaaatgg acacaactcc attcttaaca atcgatgtga ctgatatcaa
     9361 agaaaatcaa tttactgaaa tcatcaaatt ccacaaagag aattttgata ttgataatat
     9421 tgtttcatca gcttctgaat tgaaatacct caacaatctt aaagcgttcc ttactgaaaa
     9481 tatcactaca ccgtcagata gcttcctcag atatctaact tctgaaatct atgaagggcg
     9541 tgttactcaa aatatcttaa cgacattttc tcccattatt gtgaaagggt ttaatcaatt
     9601 catcacagag cgagttaatg aaaaattaag tgctgcactt aatacaagcg ttgaaaccaa
     9661 agtaacaacc gatattccaa aagttgaagc tgaagctgaa gagattgtcg aagtaactga
     9721 cgaaattatc acaactcctg ctgaattaga agtttatact gttgttaaaa tgcttgctag
     9781 ggatgtagtt tctccagaac gtgtatttta cagagataac cgtagctatt tcaatgtttt
     9841 ggttgacgat aacatcaaaa aatgggtatt acgttatcgt tcaaattcaa aaaaaagcac
     9901 tatcgaaatc cgtgataaag gcatcttccc ggtgtctacc cctctcgaag tcgcaaatta
     9961 tgccaatgaa attttagaag taatcaagaa attctcataa taaaaaaagc cctctttact
    10021 atacccattt tatcaaaaaa gtgaggtaaa atcaatgtgg atggaagaat tgccaaacgg
    10081 caaatataaa ttttttgaga gatacaaaga tccatatact gagaaattaa aaaaagtctc
    10141 agtaacgatg gagaaaaaaa ctccccaagc aagaaatcaa gctgcgattt tacttcagga
    10201 aaagataaaa caaaagttag gagaaaaaca acattctgtt tctaatataa cttttgaaaa
    10261 actatatgaa gaatttgagg agaattggaa acacggcgta aaaaactcaa ccgtctacgc
    10321 ttcaaagaat gtaaaaaaag agattttaaa gcagatagag ggcgactacc tagttagaaa
    10381 tttgatagac gtttattaca aaaagtaata gatcaactat tacaagatgg gagatctcat
    10441 aactatgttt ctaaaatcaa attcaagctc aatcagataa tgaaatttgc tatcagaatg
    10501 aattatattg atacaaatga aatgctattt gttgaaacgc ctagaaaagt aattacatcc
    10561 gacgaactca gaaagaaaaa tacaaaatac ttagaccaaa aagagtttaa gttattcatc
    10621 caaaatttaa aagacgaggc cctatgtgat tatcgaatta caaagtatat ccgaatagct
    10681 aaagttcttt ttcttactgg catgaggtat ggagagctgg cagccttaaa ctacaaggaa
    10741 gatatagatt tttctaaaaa gactattcac atcaagcata catacgattt cagacaaaaa
    10801 gagagaacta caccaaagac aatcaagtcc gatagggtta taacagcacc tcaaaaagtg
    10861 ttagatatta tcaaagagca aataatagag aatgcgacaa atggatttga tacagatttt
    10921 attttcatca atactctagg agaaccaata acaaatgcca gggttatttg tgcattgaaa
    10981 agacatggtc aaaaaatcgg catagaaaaa aacataacta cacatacatt tagacattct
    11041 cacatatccc tacttgctga gctgggcatt cccttgactg ccatcatgga cagagtaggg
    11101 catagtgact caaagaccac actagagatt tattctcacg ttactcaaaa aatggtatca
    11161 gacatatcta gcaagttaga caagataaaa ttttaaattg tgcccctcgt ctgccccttt
    11221 ttcttataca agacaaacaa aaacccctta aagtgttgat tttaaagggt ttttaaagtg
    11281 cacgaaaaaa gagcacacaa ttcaaatcgc ttagggctgc tggattcctc ccctgacccg
    11341 cttcacgcag aactgttgct ccactattta ttatatcaca ttcctattca ttttaaaagc
    11401 aaaattattt tttccgtcta tttctaaaaa aatcctgcat gatagctgcg cattcatctt
    11461 ccaaaattcc tatttcaacc tccacacgat gattgagacg ctcatctgtc aagatatcgt
    11521 acaaactccc agcagcgcca aatttctggt ttttagcccc atagaccaca tttggaatgc
    11581 gggcaagccc aatcgcccca ctacacatga cacaaggttc aatggtcaca aaaagtgtgc
    11641 aatccagcaa gcgccagctc tcctcactca agttcgcatc ctctatagcc ataatttccg
    11701 catgcataac cgctcgctgt aattcctcac gcgcattatg cccacgacca atgatttccc
    11761 catctttgac aatcacacaa ccaattggaa tttcatcgtg ttcaagagca atctcagcct
    11821 ctctcaaagc ctccctcata aagacttctt tttcttcaag cgtataatac atctcttttc
    11881 tcttttccta cttatcgatt ttattattat atcatgaatc ccaacacaaa agaagccacc
    11941 gaatgcggtg actctatagg gagattatta tgaaaaagaa aagtttagga tatttgttac
    12001 aacaagttag gaggtcttct tgtaactgtc tatagtatac ccgacctatc ttaaacaaat
    12061 cttaaaaatc tcttaggacc aaacactttc taaaatattt gtttgttcac gaccaggacc
    12121 tactgagaaa gtagaaatac gaacgccaac caattcactc acacgacgaa catagttacg
    12181 cgcattctca ggaagatctt ccaaattgcg aactccggta atatcttctg accaacctgg
    12241 caactcttca tagataggct tgcaacgttt caattgctca agactagctg gatagtagtc
    12301 aatacgttga ccgtcaagat cataggccac acagattttc acagtatcca aaccgctcaa
    12361 aacatcaata gagttcaaag aaaggttagt aataccagaa acacgacggc tatgacgcat
    12421 cacaactgag tcaaaccaac ctacacgacg tggacgacca gttgttgtac catactcatg
    12481 acccacttca cggatacgtt ctcccacttc atcaaacaac tcagttggga aaggaccatc
    12541 tcctacacga ctcgtataag ctttacatac acctacaacc ttgtcaatct tgcttggacc
    12601 gacaccagaa ccaattgtca caccaccagc tacagggttt gatgacgtaa caaatggata
    12661 agtaccttgg tcgatatcta gcataacacc ttgtgcacct tcaaaaagca cacgtttgcc
    12721 attatcaagc gcatcattca agataacaga tgtatctatc acgtatttct tgatttgttg
    12781 accatattcg taatattctt caaaaatatc atcgaaaaca atcgctttac tgtcatacaa
    12841 tttttcaaaa agacgattct tttcagcaag gttacgttct aaacgctcac ggaaaatatc
    12901 tttatctaaa agatctgcaa tacgaattcc aacacgagca gccttgtcca tataagctgg
    12961 accaattccc ttaattgtcg taccaatctt attgtcgccc ttagcttctt cttgcaagcg
    13021 atccaactcg atatgataag gcaaaataac atgcgcacga tcagaaatac gcaagttatc
    13081 agttgttaca ccttcctcat gaagatagct caactctttt acaagagatt taggatttac
    13141 aaccatacca ttcccaatga cagatatttt ttcagggaag aaaatcccag atggaatcaa
    13201 gtgcaactta aatttcttac cgtcaatcac aatcgtgtga ccagcattat caccaccttg
    13261 gtaacgtgca atcacttctg cattcgctga aaggaagtct gtaatcttcc ctttaccttc
    13321 atcaccccat tgggtaccta caacaacaac tgaagtcata attttgtctg agccctcagg
    13381 ctcttccttt ctcacataca tggcaggact ctcacctgca attatatctt acaatttatt
    13441 ataataaaaa atcgcctttt tatcaagaag aaacaataga aagatttgct atttccaact
    13501 attaaaaaat gatttagaaa aattactagc tatttactat tatctttaca taaaagagta
    13561 aattagttcg gaaatttact aaaattacct caacaagaaa taaaaccccg attcattacc
    13621 aatttttcaa gatacaaacg ataagcaaca cgataatggt aaacgataaa atccctatga
    13681 caaccaatgc catatctcac taaataataa attaaaaatt taaaatgaac atgttcccag
    13741 tcaaaattat caccaaatgt aggaccatac tcttcttcaa tactatcata gaaattagcc
    13801 atctgctcat aaattttttg taacataatc aaatactcct tttctttttt ataaacttat
    13861 tctaacaaaa aattttacac attcactatc aattcctgaa ttgttaaaat accagcctca
    13921 acaagataaa aataggaaaa gttgacaaaa tagaaacaaa tttgctacct aaatttcaaa
    13981 caattaaagt tctaaaaaga ccgccttaaa actt
//
LOCUS       DAVKBK010000044        13361 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVKBK010000044 DAVKBK010000000
VERSION     DAVKBK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.044"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            145..1491
                     /locus_tag="VWX69_001488"
     CDS             145..1491
                     /locus_tag="VWX69_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU9192809.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            complement(1827..2678)
                     /gene="rgg"
                     /locus_tag="VWX69_001489"
     CDS             complement(1827..2678)
                     /gene="rgg"
                     /locus_tag="VWX69_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU9192810.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNVAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFYTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            2802..3143
                     /locus_tag="VWX69_001490"
     CDS             2802..3143
                     /locus_tag="VWX69_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9192811.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            3201..3281
                     /locus_tag="VWX69_001491"
                     /pseudo
     CDS             3201..3281
                     /locus_tag="VWX69_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3397..5100)
                     /gene="ilvD"
                     /locus_tag="VWX69_001492"
     CDS             complement(3397..5100)
                     /gene="ilvD"
                     /locus_tag="VWX69_001492"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU9192812.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(5333..6265)
                     /locus_tag="VWX69_001493"
     CDS             complement(5333..6265)
                     /locus_tag="VWX69_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU9192813.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(6262..7119)
                     /locus_tag="VWX69_001494"
     CDS             complement(6262..7119)
                     /locus_tag="VWX69_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9192814.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(7123..8469)
                     /locus_tag="VWX69_001495"
     CDS             complement(7123..8469)
                     /locus_tag="VWX69_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9192815.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(8482..8766)
                     /locus_tag="VWX69_001496"
     CDS             complement(8482..8766)
                     /locus_tag="VWX69_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9192816.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(8770..10800)
                     /locus_tag="VWX69_001497"
     CDS             complement(8770..10800)
                     /locus_tag="VWX69_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9192817.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEYYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            10991..11998
                     /locus_tag="VWX69_001498"
     CDS             10991..11998
                     /locus_tag="VWX69_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9192818.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            12001..12201
                     /locus_tag="VWX69_001499"
     CDS             12001..12201
                     /locus_tag="VWX69_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9192819.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            12353..12535
                     /gene="rpmF"
                     /locus_tag="VWX69_001500"
     CDS             12353..12535
                     /gene="rpmF"
                     /locus_tag="VWX69_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU9192820.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            12551..12700
                     /gene="rpmG"
                     /locus_tag="VWX69_001501"
     CDS             12551..12700
                     /gene="rpmG"
                     /locus_tag="VWX69_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9192821.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(13192..>13361)
                     /locus_tag="VWX69_001502"
     CDS             complement(13192..>13361)
                     /locus_tag="VWX69_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192822.1"
                     /translation="KDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDG
                     YRVNANGEWVG"
BASE COUNT         4277 a         2816 c         2255 g         4013 t
ORIGIN      
        1 ctaaaaacca tccagaatcc ttgccttagc ttagatcctg gatggtttct tttttcaccc
       61 aatgggtgtt ttttactaga caaaaaagag tttccccttt atggtataag tgtagaaaaa
      121 aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa atcatcactt ccaaaacaag
      181 tctttttacc aactatcttt cgatggaggt catttaaccc agtatggtgg tcttatcttt
      241 tttcaggaac ttttttccca gctgaaacta aaagagcgga tttctaagta tttagtaacg
      301 aatgaccaac gccgctactg tcgttattcg gattcagata tccttgtcca gttcctcttt
      361 caactgttaa caggttatgg aacggactat gcttgtaaag aattgtcagc tgatgcctac
      421 tttccaaaat tattggaagg agggcagctt gcttcacagc caaccttatc ccgttttctt
      481 tccagaactg acgaggaaac agtccatagt ttgcgatgcc tcaaccttga attggtcgaa
      541 ttctttttac agtttcacca gctaaaccaa ctcattgtag atatcgattc tacccatttc
      601 acaacttatg gcaagcaaga aggtgttgct tataacgccc actatcgtgc tcatggctat
      661 catcctcttt atgctttcga ggggaagaca ggttattgtt tcaatgccca gcttcgtcct
      721 ggtaatcgtt attgttctga agaggcagac agctttatca cacctgtttt agaacggttt
      781 aatcaacttc tctttcgaat ggatagtggc tttgcgaccc caaaattata cgatttaatt
      841 gaaaaaacag ggcaatacta cctcataaaa ctcaagaaaa atactgttct gagccgtctt
      901 ggagaccttt ccctcccttg cccacaggat gaggacttaa ccatcttgcc ccactccgcc
      961 tactcagaaa ctctctatca agcaggatct tggtcgcaca agcgtcgtgt ctgccagttc
     1021 tctgaacgaa aagaaggaaa cttgttctac gatgttattt ctctcgttac aaatatgacg
     1081 agtggaacaa gccaagacca gtttcagctt tatcgtggac gtggtcaagc cgagaatttc
     1141 atcaaggaga tgaaggaggg attttttggc gataaaacgg atagttcaac cttaatcaaa
     1201 aacgaagttc gtatgatgat gagctgtatc gcctacaatc tctatctttt tctcaaacat
     1261 ctagctggag gtgacttcca aactttaaca atcaaacgct tccgccatct ttttcttcac
     1321 gtggtaggaa aatgtgttcg aacaggacgc aagcagctcc tcaaattgtc tagtctctat
     1381 gcctattccg aattgttttc agcactttat tctaggatta gaaaagtcaa cctgaatctt
     1441 cctgttcctt atgaaccacc tagaagaaaa gcgtcgttaa tgatgcatta aagaacagtc
     1501 gagatgaaaa aatcgtgtga cgaaccaagg gaggagtctg cccttttgag gaaatctagc
     1561 gaggaaaaac gatactggaa cagcagaaag taaaactgac ctcatgagga ggaagaaagt
     1621 ggctcatgag gtcaggggtt ttgtaagtta catctagttg agagaggtat gaatgatttg
     1681 ggagtatagc acttatgaat ttgcgaaacg attcttttga atatatgcaa caaacaaaat
     1741 gagcaaaaaa acgatagaac ttttgtaatg acctgagaga gggcaacagt tctatcgctt
     1801 caaatttttt cttggtttgc agatactcaa cattcggtcg tatttctata gtattcggca
     1861 gatttattac agccaagcat ctcaaaaata cggacagcat cctccatctt tttctgacct
     1921 tccttgactc taccttgctt gctatcaagg agaccttctg cccacagata aacaattcgg
     1981 aaataggtct cattttcctt gtagaaatgc tcttcgataa cacgtttaaa ataataggca
     2041 ttggtaaatt cttcacactc aatactagct aaaaagccat tcaatagtat agtataaaaa
     2101 aggtttcgat tgccagacat ttccattaga aaatcggatt tacgtaccat ttctcgtaca
     2161 tatctagtaa aaagagaaac agataaaaat ggagaactga ctgaaaataa attgagttca
     2221 tagattcccc agatctcggt agaaaacaaa taatcatgaa ggacttttcc ttcctctgct
     2281 gttaactcta ccctttcatc catgctcttc atataagact tgatcataat ggcatttaga
     2341 atatgtttct gtttgttgtg agaatgggca tgcttttgat actccctgcg atataagtcc
     2401 tcaagaggtg ctacattctt tggttccaag acatctgtaa tttcttttct caactcagaa
     2461 tctgtatcat actggaaacc tctcgccaga aagaggatct cctccacact ggcagatata
     2521 ttttccagag caaatagaaa cttttccacc gaaagctcac tctgacctgt ttcaaaacgg
     2581 gacaacatag acggcgaaaa ttgtcctccg gttgcttgtc tcagtgagat atttcttgac
     2641 tctcgtaatt gtctaaagac ttttccaatc tgctccatag acttcccctt gattccgtat
     2701 tttcttcatt ttatcatatt tttcagaaaa ttcatcaaaa acttgccaaa ttgtcagaat
     2761 tatgagaaaa tagaggatat ttatcacgtg gagggactgc tatgagagac gatatcaaaa
     2821 tcaatgaccg tgctttggcc ttgcaagacc aaatcatcga aaaactagag aaagtttttg
     2881 atacagatgt ggaattggat gtttacaatc taggtctgat ttatgaaatc aatctggatg
     2941 aaacggggct ctgcaagatt gtcatgacct tcaccgatac tgcctgtgat tgcgccgaaa
     3001 gcctgcctat tgaaatcgtg gcaggtctga aacaaatcga gggtatcaaa gatatcaagg
     3061 ttgaagttac ctggtcgcct gcttggaaaa tcacacgaat cagtcgctat ggccgtattg
     3121 cccttggact accacctcgt taagcaggcc aatcattttt aaagatgaaa aaagcaagcc
     3181 aaaaatggct tgctttttga tactcaatga aaatcaaagg gcaaactaga aaactagccg
     3241 caggttgctc aaaacactgt tttgaagtta tggatagaac tgacgaagtc agcccaaaac
     3301 actgttttga ggttgtggat agaactgacg aagtcagtaa ccatacctac ggcaaggcga
     3361 cgttgacgtg atttgaagag attttcaagt atgagtttat tttttacctg acttgtccat
     3421 attccagaag tctgtcacgg ctccgcgtga agcagatgat acgatatggg catatttacc
     3481 gaggacacca cggctgtaaa gtggtggcaa ggttgtttct gccttgcgtt tttcaagttc
     3541 ttcttcggat acggccatgg aaatttcttt ggtatcttgg tcaaccgtaa cgatatcgcc
     3601 ggtacggaga taggcaattg gtccaccatc ctgagcttca ggagcgatat gtccaacaac
     3661 cagaccataa gtaccaccag agaaacgtcc gtccgtcaag agggccacct tatctccctg
     3721 acctttacca acaatcattg aagaaagtga cagcatctca ggcataccag gaccaccttt
     3781 aggtccaaca aaacgaacaa cgactacatc gccatcaacg atttcatctg tcagaacggc
     3841 ctgaatcgca tcttcttctg agtcaaagac cttagctggc ccaacgtgac gacgcacttt
     3901 aacacctgat accttggcaa ctgcaccgtc aggagcaagg ttcccgttca agatgataag
     3961 cggaccatcc gcacgttttg gattttcaag tggcatgata actttttggc ctggagtcaa
     4021 gtctgcaaag tcagccaagt tttcagctac agtcttacca gtacatgtga tgcgatctcc
     4081 gtgaaggaaa ccatttgcca acaagtactt cataaccgca gggacaccac cgacttcgta
     4141 gaggtcttgg aagacatact gaccagatgg tttcaagtcg gccaagtgag gcacacgttc
     4201 ttgaatcgta ttgaagtcct caagtgacaa gtcaacattt gcggcatggg caatggcgag
     4261 caagtgaaga gtggcgtttg tagaaccacc gagagccatc gttacagtaa tagcatcttc
     4321 aaaggcttca cgagtcaaga tatctgatgg tttgagacca agttccaaca tcttaacaac
     4381 agcacgtcct gctgcttcga tatcttcttt cttatcagct gattcagctg ggtgagagga
     4441 tgaccctggc aaactcatcc ctagaacttc gatagcagtt gccatggtat tagcagtata
     4501 cataccacca caaccaccag ggccagggca ggcattacat tcaagacgtt tcacgtcctc
     4561 agctgtcatg tcaccgtggt tccattttcc gataccttca aagacagaaa ccaagtcgat
     4621 atctttacca tcaagatttc ccggtgcaat agttccacca taggcgaaaa tagctgggat
     4681 atccatatta gcaatagcaa tcatagatcc aggcatgttc ttgtcacagc caccgatagc
     4741 gacgaaggca tccacgttgt gaccactcat agccgcctcg atggagtccg cgatgatgtc
     4801 acgagatgtt agagagaaac gcataccagg cgttcccata gcgatcccgt ccgctacggt
     4861 aatggttcca aactgtacag gccaagcgcc tgcagatttg acaccttctt tagccagttt
     4921 cccgaaatca tgcaagtgaa tgttacatgg tgtattttcc gcccaagtcg aaatcactcc
     4981 cacaatcgat gtttcaaagt ccttatctgt cataccagtc gcacgaagca tagcacggtt
     5041 aggtgattta accatgctgt catagatgct actgcggtga cgtttatcta attcagtcat
     5101 cttatccctc ccatttcagt ttttactatt atagcacaat ttaaaggcaa tgaacagaat
     5161 aaaattcttg aattttcaga aaattctata cgcatgtgaa atatttaaaa ttaaaaacaa
     5221 caaagcggat tagtgcactt tctgatgacc agaatatgct ttttaatccg ctttctttaa
     5281 ataacgtact gtaattttta cagaaattct ttcagataag tgtatttaac atctatcttg
     5341 cattataaat ttctagaacc ttctctttta tattcgattc actcaaacca tactcattaa
     5401 gaagataatc cattttccct acttgaccga atctttcttg aacacccatc cgatgaattt
     5461 ttgttattcc atcatcagag aataattcac ataaagcact gccaattcca cctatctgat
     5521 tgtggttttc tacagtaaat atagtttttc cacttaacat tgtttttatc tgttctggta
     5581 tcggtttgat tctaaataaa tctatcacac ttactgaata acctaattta gacagttcat
     5641 ctgcaactcg aatacttgga gcaaccatta taccagaagc aacgattaca agatcttcac
     5701 catgccttaa ctcaatgtag cctttagaaa aatcttctcc accttgatac acaggaactg
     5761 gagcttttct aattgttcga atatatttta gtccttttaa gtctaatgtc tggttcaata
     5821 tttcacgaaa ttggatatca tcagttgctt caaaaatgat cgatttagga attaaacgta
     5881 acaatccaat ttcttcaaat ggcatatgtg tcccaccatt catttctgca gttactcctg
     5941 catctgatcc aatcacagtg gcatccaatt gtgcgtatcc aagagaaata aataattgat
     6001 caaatactct tcgtgaagca aaaggaccaa atgtatgaag ataaggtcta aacccctgaa
     6061 tagacaagcc tgctgcaagg ccgaccattt ctgcttccat aatcccaaca ttcacataac
     6121 ggtctccaaa gtccttttca agattatgag tagccatcga acttgacaaa tcggcttcta
     6181 agactactat atcagaatca ctttgattag cctctaaaag gaagtctcta tatacatgcc
     6241 gtaattcttt cgtgcttctc atcattctgt ttcctccaat tcctgactta atctttctac
     6301 aactgaggtt aacatttgtc tctcctctac agtagggcga agatgatgat tggatttcat
     6361 ttcttccagc tcttgaaccc cttgaccttt aatagtatct aatacaatgc acttaggtga
     6421 tgaattattt gactgtttta attggacaat cccttcataa atttctctaa tatctgaacc
     6481 cttgacccta atggattcaa atccaaatgc tgaaaatttt tctacgaaat cacctggatt
     6541 acaaatatcc tttgtaaaac catctaattg ttttttgtta tcatcaacaa atacaattaa
     6601 gttggataac tgttgatgag aagcaaactg tatagcctcc caacattgtc cctcatttaa
     6661 ctcaccatct ccaacaatag cataagtata aaagggactc tttcttattc tctgaccata
     6721 tgcaagtcca gttgcaacac taattccttg tcctaaagag cccgttgtca tatctatgcc
     6781 tggcgttaga tttctatcag gatgagacgg taatttggtt ccatttgtat ttaaagaata
     6841 taagaattct ttgtcaaaga aaccattcaa atagagtgta ctgtatagag ctggtcctcc
     6901 atgacctttt gataatatga aataatctct atctcgtgct gcaaatattt ctggagtcat
     6961 tggcattatt tcaccataaa gcactgctaa aacttctacg atagacagac ttcctccgta
     7021 atgtccgaat ccaagatgat tcaatgttct aagagtattt aatcggatgt tagtcgcaaa
     7081 ttttcttaac ccatcttctc tatttttact taaaatcatc ccttattcct cctttgcaga
     7141 tggcttttta ataaaggata ctccaaacat aactgctaga ataagaacaa gaccaatcac
     7201 aatgcctgct tgtgagccaa attgatttaa cattcctaaa ataattcctg atagaccaaa
     7261 atctgcatct gagaaagttg atccttggaa accaagtcct cccaaaactg gcattaaaaa
     7321 gactggaaga aaactgatta aaataccttg taaaaatgct ccaatagtgg ctccacgaac
     7381 accaccagat gcattcccaa tgacacctgc agtcgctcca cagaagaaat gaggcacaac
     7441 acctggtaag ataacaaccg ttcctgaagc aatcataatt gccatactta ctaaaccacc
     7501 aataaaacta gagataaatc caattagaac tgcattgggt gcataagtat aaacaatcgg
     7561 acaatccaaa gcaggttttg aattaggtac aagacgctct gaaatacctt taaaggctgg
     7621 aacaatttcg cccaaaataa ggcgaacacc tgctaaaata acaaataccc ctgctgcaaa
     7681 ttgacctgct aattgtaaag cataaactag accacttgta ccactactga tttctttttc
     7741 tatatattct gaccctgcaa agatagctac aataatgtaa ataactgcca tggataaagt
     7801 aatactaaca gtactatcac gtaaaaaagc taaactcttt ggaaatttaa tgtcctctgt
     7861 tgattttgat ttgtcaccga taaggctacc agtaaaacca ctcaaccaat atcccaaaga
     7921 actgaaatga cctaaagcca ccttgtcatt tccagttaat tgaaccatat atttttgaac
     7981 aaatgctggg gaaatactca taataatacc gagtgctaat cctcctagta agataagagg
     8041 caagctagta aagccagcaa ctgataaaat gaccgcaatc atacatgcca tatatagagt
     8101 gtggtgccct gttaaaaaaa tatatttaaa tcgagtaaaa cgagcgatta agatattgaa
     8161 caccatgcct gcaaacataa tcagtgcagt agctgagcca tatgttgtta aagctacagc
     8221 tacaattgct tcattattcg gcacaacgcc agataaatga aaagcatgct caaacatggt
     8281 accaaatgga tttaaagaat tttgtacaat tcctgcacca ccagatacaa ctaagaaacc
     8341 aacaaaggtc ttaattccac ctttaataat atcaggtaat ttcttcttct gaagaactaa
     8401 tcctaaaatt gcaattaaag ctactaaaat agctggtgta ctaacaatat ccaatatgaa
     8461 cttcatcatg acgctagcct cctatataag tcctttttct tcacaaagtt tagtaattaa
     8521 ttctcgtagt tcatccatat caataatact atttaagata cgaacatctc caagatgact
     8581 agctgaatca gctagatcac gaccaacaat ccaaatatca gctgcatttg gatctgctcc
     8641 acctaaatca taatgttcaa cttctacatc tgaaacattc aaatcactca atacagattc
     8701 aatattcatc tgtaccataa aacttgaacc taatcctgaa ccacaagctg taccaatttt
     8761 taacattatc taatcctcct gtttaattat cattttaatg tcatcatagt tttttgatga
     8821 tattaaagtt tgaacatgat ttttatctct taaaattgtt gttaaatgtg acaaagcctt
     8881 taaatgactc tcattatcaa tggctgcaat acaaatcaac aatcttacct cttgttctgg
     8941 attatccaat aaataaatcg gttcttccaa aactaacatt gacattccta tttcattcac
     9001 accttcatct ggccgagcgt gaggaattgc tactcccttc cctaaattaa taaaaggccc
     9061 aaactcttct actttttgaa tcattgcctc agggtagttc tcagttatct tatcttgatc
     9121 caaaagcggt ttagctgcta aacgaatcgc ctccttccat cctaattttt gcgaactaac
     9181 ctgataggtt tctttggtaa tgagttgttc tagcactggt acaatttcct ttctatcatt
     9241 tttttggtaa agataattct ttaacgccaa tcttaattcc aattcttgtg taataattcc
     9301 atatcttttg acaatattca gaatttgttc aatctcaaaa tccccatact ctaaattcgg
     9361 aaaatctttt aacactagtt ctactagttg tattgcttgc tcttcagtca tcataaccga
     9421 aactagataa tttggctttt ctgtctccac ctttatggta gaaaaaacca tatcatagtc
     9481 actactagct ttcacctgta aatcatcaat ctttgaggtt cctataaact caatttgagg
     9541 aaataatgct aatagattct cttttaacat caatgaagaa ctaacaccat taggacaaat
     9601 gattgctgct ttataccatt tttgaggcaa agtatctgct ttctttaaat aacctccgaa
     9661 atggataaca aaatatgctg tttcactatc aggtatggga ttgtcaatag cgtccatcaa
     9721 gggcatcaaa gaatctttga ctaattcaaa taaatcagga taatattctt taacatgcaa
     9781 tacatattca tttgaactag gtaggccgaa ctttaatcta tagtaagccg gtataaggtg
     9841 gcggcgaaga ttttctctca atccttccct ttgtttaaaa tgtaacaaag aaatatcttc
     9901 cattctactt ataatagcct ctgttaattg attaaagtaa accggagcaa catctacttc
     9961 accttcaaag caacttgata ataaaactgt gatatagcga taatcatcct cagaaaacac
    10021 cgtatctata attcccaaat caaccactgt atccaataaa atagtggtta tatcttgaat
    10081 aacaggagat actaatgtct ctgaaagaca tactctttca acatcccttt gatacctaca
    10141 cagaatgaat actaaaccga aaaggcaaac ttttaattga ttaacaatag gtactagttg
    10201 tagcttctca taataatctt taactacctg atttatcaaa tcataagtta atgaataccc
    10261 ccaactggat aaaacataat ccaaacccca aatccctatg gaggattcca gcaactcact
    10321 aaccatttga aaagctaagc ggtgcttatt ccactctgaa ccgtgtaaag tataaccttt
    10381 tgctctactg taccctagct ccaaatcatt atctaacata atctttctta atgattgaat
    10441 atcagataag gttgtattct tacttacttt caaaaagtct tggtaatgat tattcgatat
    10501 aaaatctaat cggcaaaaag tgtaaagata gattaaagct aagcgagtcg actttggtaa
    10561 aaccaattca tccgacttaa taatatctgt caaagactgc ttcgtacgat ttgataaact
    10621 atagcgacct tgttttttat ccagcactat ccctttatta gctagataag gcactaaata
    10681 atctattcct tctttgactt cctttatagg taagctcacc ttaacagata attcatataa
    10741 tgatagctca caatgatcca tcaaagtcat caaaataact agtgctctat aatcaaacat
    10801 ttctcttcct ttctaactac aattatagtg taaaaattat aagaataaaa gagtatttga
    10861 gcacaatata atctcacctt ttaaaagaaa ttattgggct gaaagttttt agtgattatt
    10921 ttcaactttc tattgacttt taaaaacaaa gtgatatcat ttagatatca aataatggga
    10981 ggtcattctt atgactgaaa aactaatcaa ttcaaaacca aatggtgtat tcgcattgat
    11041 tctcattgag ttgacaatcg tacttggtgt ctttatattt ataatgggtg ttggttcgga
    11101 aaacattttt ggaattatta tcggaccttt actaatcgta attgcaggtc tagctcatgc
    11161 tggtttaaaa gttgtcaaac ctcaggaagc tctggttctg acactctttg gtaactatac
    11221 aggtaccatc aaagaacctg gtttttactt tgtcaatccc ttcagcgtag cagtcaaccc
    11281 tgcaaaccac actcgacttg gacaaagtgg tgatgttagc acaaaatctc cttttttagg
    11341 agctaaatca tcaaatgaca atgatgtaaa tcttgaaatt ggcaagaaac agatttccct
    11401 caaagtcatg accttgagca attctcgtca aaaaatcaat gattgcttag gaaaccctgt
    11461 agaaatcggt atcgcggtaa cttggagagt tgtcgatacc gctaaggcag tcttcaacgt
    11521 tgataactac aaagaatatc tttcattgca atgtgatagc gccctccgta atattgtccg
    11581 catctatcct tacgatgtgt ctcctaatgt ggatactacg ggtgacgggc aagcagatga
    11641 aggtagtctc cgtggctcta gcgaaattgt tgctaaccgt attcgtgaag aaatccaaag
    11701 tcgtgttgag gatgctggct tggaaatcct tgaagcacgt atcacttacc tagcttatgc
    11761 tccagaaatt gctgccgtta tgcttcaacg ccaacaagca tctgccatta ttgatgcacg
    11821 gaagatgatt gtagatggtg ctgtaggaat ggttgaaatg gcactagaac ggctcaatga
    11881 aggggaattg gtagaacttg acgaagaacg aaaagctgcc atggtttcaa atctccttgt
    11941 cgttctttgt ggcaatcatg atgcacaacc aattgtcaac acaggaagtc tttactaaag
    12001 atggctgaag ctaaaaaaaa gcagatcccc cttcgactct caacaaagtt atacgctgca
    12061 ctcgcatcat gggcagaaga cgactttcgt tcagtcaatg ggcaaatcga atatctcctc
    12121 acagagtgtg tcaagcaacg gaagaaagac ggaaaatacg tatcagaaac cattgacgaa
    12181 ccatttgaga ttgatattta acatcttctc ctgtctgaca agtcggacag gagaattttt
    12241 tcatcttttt ttgtcaagta actttacttt acaaaaaaaa tgtgttatcc tagtatggtt
    12301 gatgaaaatc agtagattga atcgaatata aatacctaaa ggagaaatca aaatggcagt
    12361 acctgcacgt cgcacttcaa aagcgaagaa aaacaaacgt cgtacacact acaaagtaac
    12421 agctccatct gtaaactttg acgaaactac tggagattac tcacgttctc accgtgtatc
    12481 acttaaagga tactacaaag gacgtaaaat cgctaaagct gcatcagctg aataatagaa
    12541 gggagatacc atgcgcgtaa atattacact tgaacacaaa gaatctggtg aacgcttgta
    12601 ccttacttct aaaaacaaac gtaacactcc agaccgcctt caattgaaga aatactcacc
    12661 aaaacttcgc aaacacgttg tgtttacaga agttaagtaa gcattcaata cgaatcaata
    12721 cagaagaaaa acgcttgatc agcgtttttt ctttttgtta atttcactat attgcaaggg
    12781 aaatcattcg aatgactaca tttttcacta ccttttttga aataagaata cggattcgga
    12841 cgattaaaag taagagaaac tcaaatgtaa gttggggttc cttttttgta tatttttcaa
    12901 ataacgcctc tacactattt gtagcaaatt caccaactac agttgtatct tagttaaaat
    12961 aagttagaat atgtaagtga gtaccagata taccaagaca tcgtcaccat ctaaggtata
    13021 ttcaaaatac aaaagttgac caactagatt tctgaatatc cttatatatc cattcttaaa
    13081 attggtttaa atagcgtagt cttttaaact agttttgaga atccaaaaaa tcttcctaca
    13141 tatgtaagaa gattttttag ttcagaatga ttagatttag ctaatggata cctatcctac
    13201 ccactcaccg ttagcattga ctcgatagcc atcgggtgta gtcgtgttta ctaataaatc
    13261 tcctgaatta taggtatagt accatttacc agaaactgta aaccaaccag tagccattga
    13321 acctgattcg tttaagtaat accataagcc tttgtcttta a
//
LOCUS       DAVKBK010000045        13237 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVKBK010000045 DAVKBK010000000
VERSION     DAVKBK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.045"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            73..288
                     /locus_tag="VWX69_001503"
     CDS             73..288
                     /locus_tag="VWX69_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192823.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(379..1119)
                     /locus_tag="VWX69_001504"
     CDS             complement(379..1119)
                     /locus_tag="VWX69_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9192824.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQELAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(1119..2684)
                     /locus_tag="VWX69_001505"
     CDS             complement(1119..2684)
                     /locus_tag="VWX69_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9192825.1"
                     /translation="MRKIYLSIFTSLLLMLGFVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLIKKDSAYANAKSLDDFNGAKITSQQGVYLYD
                     LIGQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEVANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDNRISQINASIETISKDEQVALMDRMIKEQPAEATTTEETSS
                     SFFNQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            2823..4712
                     /locus_tag="VWX69_001506"
     CDS             2823..4712
                     /locus_tag="VWX69_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU9192826.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELTDVTSEVIEGAD
                     GYTVKVYNPGQEGDTVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSGAIGKFEFNVRG
                     DKGAEKLFFHTGKLFKEGTVEKSNLDYTIRLDNLPSKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKSQSKQLVTWVFPSILSISLLLSVCFYFIYRRKTTISVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLTKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRGA
                     KVSDEKRIQAKGRQLKSSFEEVLKEMQEGVRNRVSFWGLPDYYRPLTGWEKALQVGMG
                     LSTILPLFIGFGFFLYSLDVHDYLYLPLPILGFLGLVLAVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            complement(4911..5882)
                     /locus_tag="VWX69_001507"
     CDS             complement(4911..5882)
                     /locus_tag="VWX69_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU9192827.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALKLLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCLD
                     IIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPR
                     SIETTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILA
                     EIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKVCARF
                     SPAFKAYLKTKLEQGKHYNVAIIHLAKKLIRTLFYILKKSCHLTNKK"
     gene            5969..6106
                     /locus_tag="VWX69_001508"
     CDS             5969..6106
                     /locus_tag="VWX69_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192828.1"
                     /translation="MRYQTHYQLKQKLWLDPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            6137..6982
                     /locus_tag="VWX69_001509"
     CDS             6137..6982
                     /locus_tag="VWX69_001509"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU9192829.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(7129..8190)
                     /gene="dinB"
                     /locus_tag="VWX69_001510"
     CDS             complement(7129..8190)
                     /gene="dinB"
                     /locus_tag="VWX69_001510"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU9192830.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            8584..10908
                     /gene="pflB"
                     /locus_tag="VWX69_001511"
     CDS             8584..10908
                     /gene="pflB"
                     /locus_tag="VWX69_001511"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU9192831.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(11275..11493)
                     /locus_tag="VWX69_001512"
     CDS             complement(11275..11493)
                     /locus_tag="VWX69_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192832.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(11589..11827)
                     /locus_tag="VWX69_001513"
                     /pseudo
     CDS             complement(11589..11827)
                     /locus_tag="VWX69_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11820..12104)
                     /locus_tag="VWX69_001514"
     CDS             complement(11820..12104)
                     /locus_tag="VWX69_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192833.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(12716..12898)
                     /locus_tag="VWX69_001515"
                     /pseudo
     CDS             complement(12716..12898)
                     /locus_tag="VWX69_001515"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3848 a         2441 c         2716 g         4232 t
ORIGIN      
        1 tgttttttta ttgacaaaag acataaaaac gtatagaata atatatcgta aagaagaaaa
       61 taggagaagg acatggctaa gtcaaacttt gaaaaagtag aatcagttgt tggctgggtt
      121 cgtgataaga aaatcacagg ctaccgtatc tctaaagaaa cgaatgcgcg tgaaatgtct
      181 atcattgctc tagcgcaggg tcgtgcaaaa gtaaaaaata tttcatttga aacagctcta
      241 ggtttaattg atttctatga aaaaaatcat gaaaaatttg aagattaatc tttggataat
      301 ggcggattct tgaattgggt ctgccttttc attttgagga cagcaaaaag actgcatggt
      361 tgatgcagcc ttttcttttt atttgagata gcgttgaagg aattcttttg tacggtcttc
      421 tttaggattg gtgaagaggt cttctggttt accttcttca gcaatcacac ccttatccat
      481 aaagataaca cggtgagaga catcacgagc gaattccatc tcgtgagtca ctacaatcat
      541 ggtcaagcct tcctgagcta gttcttgcat gattttaagg acttctccaa ccatttctgg
      601 atcgagagct gatgttggtt catcaaagag aatggcgtca ggattcattg aaagggcgcg
      661 agcgatggcc acacgttgtt tttgaccacc tgagagttgt tttggtttcg cttgccagta
      721 gcgttctccc atgccgactt tttctaggtt ttctttggca attttttcag cttctgtacg
      781 ttcgcgttta aggacagtcg tctgagcgac gattgtgttt tcaagaacgt tgagattctc
      841 aaagagatta aaggattgga acaccattcc tagtttttca cggtattgtg tgaggtcata
      901 acctttttcg aggacgtttt gtccatgata aaggatttgt ccatcggttg gcgtttcaag
      961 taggttaatg gagcgtagga aggtcgattt tccgcttcca gagcttccga tgatagagat
     1021 gacttctccc ttatggacag tgagagaaat atcttttagc acttcgtttt gtccatagga
     1081 ttttttgagg tgtttaattt caaggattgc ttgtgtcatt atttcaaatc ctccgtttgc
     1141 atttgattag cacctgtagt ataggtatcc atatccattc ggcgctcgat gaagcggagg
     1201 atacgtgtta cggtgaaggt gaggacaaag taaatcacgg cgatgattgt aaatgtctgg
     1261 aagtattgat aggtttgagt tgccacggta tttcctgaga aataaagttc gacaacagag
     1321 ataacgttca atacagatgt atctttgata ttgatgacaa attcattacc agttgctggt
     1381 aggatgttac ggactacctg aggtaagaca atcttacgca tggtttggtt atgagtcata
     1441 ccaagagcgg tcgctgcttc aaattgtccc ttgtcaactg ctaggatacc accacggacg
     1501 atttcagtca tgtaggcacc agtgttgatt gaaacgatga agatagcagc cagtgtgcgg
     1561 tcaaggttga taccgaaagc ttgagcggtt ccatagtaga taaccatcga ttgaacaatc
     1621 ataggtgtac cacggaaaat ttcgatatag acattgagaa tccagccgac tagtttttgt
     1681 aggccataaa tggctttatt ctcagagaga ggagcagtac ggaaaacacc aatagcaagg
     1741 ccaataatga gacctatgat ggttccgacg atagagatta aaagagtgat accagcacca
     1801 cgcaagagtt gttgccagtt ttcagaaaga attttagcga cttggttaaa gaaactactg
     1861 ctagtctctt cagttgttgt agcttcggca ggttgttcct tgatcatacg atccatcagg
     1921 gcaacttgct catcttttga aatagtttca atgctggcat tgatctggct aatacgattg
     1981 tcatctttac gaagtccaat ggcaatagct gtatcttctt ctccagtttt gaaacctggt
     2041 tctacttgaa ccatcttgaa cttagagtta gcaacttcgg cagtcagtgc ttcagggcgc
     2101 tcagaaacat aggcatcgat gacaccagcc tcaagtgctt ggcgcatttg agcgaagtct
     2161 cccatggctg tttctttttt agcgcctggg atttgaccaa tcaagtcata aaggtaaacc
     2221 ccttgttggg aagtgatttt cgcaccatta aagtcatcca aagatttagc attcgcatag
     2281 gcagaatctt ttttgatgag taagacaggt tcgctagtgt agtaactgct tgaaaaggcg
     2341 atttcttgtt tgcgttcggc agtaggactc atacctgcga taatcatatc aatcttacca
     2401 gaagtaaggg cagggactag accttcccac ttggttttaa caaccaaagg ctctttgcct
     2461 aagtccttag caattttctt ggcaatctgg acatcgtatc cattggcgta ctggttggtt
     2521 ccatcgattt tgacagctcc attgctatca tcatcctggg tccagttaaa gggggcatat
     2581 gctgcttcca tcccgatgcg taaatattca tcggcttgag caacattgac aaatcctagc
     2641 atcagcaaga gacttgtgaa aatagataag tatatttttc tcatgatttc tcctatttct
     2701 aatctattaa aaaataactg tctcctattt tatcgaaaaa aactctattt ttcaatacag
     2761 gtaagccctt acttgagaaa aaatgatata atgatagcaa agataaaaag ggggcttaat
     2821 tgatgaaaaa aacttttttc ttactggtct taggcttgtt ttgccttctg ccactctctg
     2881 tttttgccat tgatttcaag ataaactcct accaagggga tttgtatatt catgcagaca
     2941 acacggcaga atttagacaa aagatagttt atcagtttga ggaggacttt aaaggccaaa
     3001 tcgtggggct tggacgtgct ggcaagatgc ctagcggatt tgacattgat cctcatccaa
     3061 aggttcaggc tgcgaaaaat ggtgctgaac tgacagatgt tacgagtgaa gtgatagaag
     3121 gagcagatgg ttatactgtt aaagtttata atccaggtca ggaaggcgac acagttgaag
     3181 ttgaccttgt ctggaactta aagaacttgc tttttcttta tgatgatatc gctgaattaa
     3241 attggcaacc tctgacagat agttcagggg ctattggcaa gtttgaattt aatgtaaggg
     3301 gtgataaggg ggctgaaaaa ctctttttcc acacaggaaa actttttaaa gaaggaacgg
     3361 ttgaaaagag taaccttgat tatactattc gtttagacaa tcttccgtct aagcgtggag
     3421 ttgaattgca tgcctactgg tctcgaactg attttgctag cgctagggat cagggcttga
     3481 aagggaatcg tttagaggag tttaataaga tagaagactc gattgttaga gaaaaatctc
     3541 agagtaaaca actcgtcact tgggtctttc cttcgatcct ttccatctct ttgttattga
     3601 gcgtctgctt ctattttatt tatagaagaa agaccactat ttcagtcaaa tatgctaaaa
     3661 atcatcgtct ctatgaacca ccaatggaat tagagcctat ggttttatca gaggctgtct
     3721 actcgacctc cttagaggaa gtgagtcctc taaccaaagg agcaggaaaa ttcacctttg
     3781 accaacttat tcaagctacc ttgctagatg tgatagaccg tgggaatgtc tctatcattt
     3841 cagaaggaga tgcagttgga ttaaggctgg taaaagaaga tggtttgtcc agttttgaga
     3901 aagactgtct aaatctggct ttttcaggca aaaaagaaga aactctttcc aatttgtttg
     3961 cggattacaa ggtatctgat agtctttatc gtggggcaaa agtctctgat gaaaaacgga
     4021 ttcaagcaaa gggacgtcag ctcaaatcat cttttgaaga ggtattgaaa gagatgcaag
     4081 aaggggtaag aaatcgagtt tccttttggg ggcttccaga ttattatcgt cccttgactg
     4141 gctgggaaaa ggccttgcag gtggggatgg gactctccac tatcttgccc ttatttattg
     4201 gatttggttt cttcttgtac agtttagacg ttcatgacta tctttacctc cccttgccaa
     4261 tacttggttt tctaggtttg gttttggctg ttttctatta ttggaagctt cgactagata
     4321 atcgtgatgg tgtcttaaat gaagcgggag cagaagtcta ctatctctgg accagttttg
     4381 aaaatatgtt acgtgagatt gcacgactgg ataaggctga attggaaagt attgttgttt
     4441 ggaatcgtct cttggtctat gcaaccttat ttggctatgc ggacaaggtt agtcatttga
     4501 tgaaggttca tcagattcaa gttgaaaatc cagatatcaa tctctatgta gcttatggct
     4561 ggcacagtat gttttatcat tcaagcgcgc aaatgagcca ttatgctagt gtcgcaaata
     4621 cagcaagtac ctactccgta tcttctggaa gtggaagttc tggcggtggc ttctctggag
     4681 gcggaggtgg cggcagtatc ggagcctttt aaagagagct accatagact gaaaaagtat
     4741 gatataatgg aagatagaag aaagacaaac tataagaaaa gtcaatagtt ttatctaaac
     4801 tatttcttat ttcaatttga tgatttggcg atgattttag agcacggcaa aaagcccttg
     4861 aaaaagtcca ttttttcaaa ggtaatcctg tgttaatttc agaaattaca tcactttttg
     4921 ttcgtcaaat ggcagctctt ttttaggata taaaacaggg ttcggataag tttttttgca
     4981 aggtggatga tggctacatt gtaatgtttt ccttgttcta acttagtctt aagataggcc
     5041 ttaaaagcag gtgaaaagcg agcgcatact ttggcagctt gtatgagtgc ccaccgcaga
     5101 tgaggggaac cccgtttgat cattcttcca gctaaatcaa tctgacctga ctgataaata
     5161 gaagaatcca gtccagcgaa agcttgtaat tgagcaggat tatcaaaggc atgaatattt
     5221 cgaatctcgg ctaaaatgac cgcccctaaa cgacccccaa tcccagtaac cgtcgtgatg
     5281 actgagttga actcagccat caagtcattg acacatgttt ccgccttgtc aatgagcctc
     5341 ttgtaatgtt tgatgatttc gatgatttcg aattcacgag caggagatgt tgtttcgata
     5401 gaacgaggtg cgactgagag gatatcctga attttagaag cggtcaatcg cttaatttct
     5461 atcagcttat caaatcctgc ctcaatcctt ttctgaggat tagggtagcg cgtcaagagt
     5521 tggtaggtat attctgaatg ctttccaacg attttatcca actcaggaaa gatgatatca
     5581 agacaacgag tgtattgtac tttccaatca gactgttttt tcttgagacg atgaatatgt
     5641 ctagccagta tttttaggtc tacttgccga ttatcgtgtt gaaattgttc acgattggga
     5701 tcagaaagaa gtttaagagc gatgagacag tcttggttga gctgtcgaag agacagatct
     5761 aagagttcaa aaccagcttt attatttgaa aaagtgagtg gtttaagaac agtttttcct
     5821 ggaacattca aggctgtaac atcgtgttta tttttagcga tatcaatgcc cacataaagc
     5881 atgggagtac ctccagatat agtatttcaa gtctacttgg ttatccacga actttttgcc
     5941 ttgttacctt agacgagata aaacgtctat gcgttatcaa actcattacc aattgaaaca
     6001 aaagctgtgg ttagatcctt tcggaaatcg tcaagcgatt ggaggaaatg aactaatcca
     6061 cagtggctta ttccaagtat accacttggg ctttggcagt agctaactgc gctaattata
     6121 atatagggag taatctatgt atcttattga aattttaaaa tctatcttct tcgggattgt
     6181 tgaaggaatt acggaatggt tgccgatttc cagtacaggt cacttgattt tagcagagga
     6241 attcatccaa taccaaaatc aaaatgaagc ctttatgtcc atgtttaatg tcgtgattca
     6301 gcttggtgct attttagcag ttatggtgat ttattttaac aagctcaatc cttttaaacc
     6361 gactaaggac aaacaggaag ttcgtaagac ttggagacta tggttgaagg tcttgattgc
     6421 tactttacct ttacttggtg tctttaaatt tgatgattgg tttgataccc acttccataa
     6481 catggtttca gttgctctca tgttgattat ctacggggtt gccttcatct atttggaaaa
     6541 gcgcaataaa gcgcgtgcta tcgagccaag tgtaacagag ttggacaagc ttccttatac
     6601 gaccgctttc tatatcggac tcttccaagt tcttgctctt ttaccaggga ctagccgttc
     6661 aggtgcaacg attgtcggtg gtttgttaaa tggaaccagt cgttcagttg tgacagaatt
     6721 taccttctat cttgggattc ctgttatgtt tggagctagt gccttaaaga ttttcaaatt
     6781 tgtgaaagcc ggagaactct tgagctttgg gcaattgttt ttgctcttgg tcgcgatggg
     6841 agtagctttt gcggtcagca tggtggctat tcgcttcttg accagctatg tgaaaaaaca
     6901 cgacttcacc ctttttggta aataccgtat cgtgcttggt agtgttttgc tactttacag
     6961 ttttgtccgt ttatttgtat aagaaaaacc ttgaaggggc aactcttcaa ggttttatac
     7021 tcttcgaaaa tctcttcaaa ccgcgtcagc tttatctgca acctcaaaac agtgttttga
     7081 gcagcctgcg gctagcctcc tagtttgctc tttgattttc attgagcttt aaaatccagt
     7141 catggtaatc cccaataggc ggacacctct ttctttcttg cttaattctt catagagttg
     7201 cagggctatt tggcttatct gactagcatc ttgtgttttt tgagcaagac tttttcgttt
     7261 ggtaagagtt gaaaagtcct cgtagcggat tttcaaaatg acaatttttc cagctttttc
     7321 ttgttgatgt agattgagag cgactttttc tgatagaaga gtcagctctt ttttgatatc
     7381 ttcctcagca aggagaatct tcccgtaggt tttctccttg ccgattgatt tacggatgcg
     7441 attggatttg actggagagt tgtgaatgcc acgagccttt cgatacagat catagcctag
     7501 tctaccaaaa cggtctatta gggttacctc aggaacttca agtaaatcag caccagtaaa
     7561 aacgcccatt tgatgaagac gttctactgt cttttttcct actccatgaa atttggaaat
     7621 atccatttgt ttgagaaaat cctcagcctg ttcaggtaga atcactgtca aaccatgtgg
     7681 tttttgataa tcactcgcca ttttagctaa gaacttgtta taggaaatac cggcagaagc
     7741 agttagatgg agttcttgcc agatatcttt ttgaatgagg cgagcaattt tgaccgctga
     7801 cttgataccg agtttatttt ctgtcacatc caaataggct tcgtcaatgc tcatgggttc
     7861 aatcaaatct gtatagcgct taaaaatagc tcgaatctgg agtcccacag ctttgtattt
     7921 ctcataattt cctgagataa agacggcctg gggacaacgt tcataagctt ccttggaact
     7981 catggcagaa tggacaccaa aagctcgagc ctcatagcta caggtagaaa cgactccccg
     8041 tccacctgtt tgccgagggt cgcttccaat aatgacaggt tttcctctga gtttaggatt
     8101 atccttgatt tccaccgcag caaaaaaggc atccatgtca atatggatga tttttcttga
     8161 caaatcattt agcaaaggaa aaatcaacat gcctagcacc tttttatact tttcgaaaat
     8221 ctcttcaaac cacgtcagct tccatctgca acctcaaaac agtattttga gctgacttcg
     8281 tcagttctat ttacaacctc aaagcagtgc tttgagcagc ctgcggctag cttcctagtt
     8341 tgcttttcga tttccattga gtgttactgc ttattttctt ttattatacc cttttttctg
     8401 aaaaaaagaa aaaaggactt tattttttca aaaatataat acagtttgaa ataaaatata
     8461 gactgtttta gaaaagaaag tgtaaaaata gggatttttc acttgttaaa atcggttact
     8521 atatggtata cttgtctcat gaatgtaaca gatgactgtt actagaaaaa agaggacatt
     8581 aatatggttg ttaagacagt tgttgaagca caagatattt ttgacaaagc ttgggaaggc
     8641 ttcaaaggcg tagattggaa agaaaaagca agtgtatcac gctttgtaca agctaactac
     8701 acaccttatg atggagacga aagcttcctt gcaggaccaa cagagcgttc acttcacatc
     8761 aagaaaattg tagaagaaac taaagcacac tacgaagaaa ctcgtttccc aatggacact
     8821 cgtccaacat ctatcgctga tatccctgct ggatttatcg acaaagaaaa tgaagttatc
     8881 ttcggtatcc aaaacgatga actcttcaaa ttgaacttca tgccaaaagg tggtatccgt
     8941 atggctgaaa ctactttgaa agaaaatgga tacgaaccag acccagctgt tcacgaaatc
     9001 ttcactaaat atgtaacaac agttaacgac ggtattttcc gtgcctacac ttcaaatatt
     9061 cgtcgcgctc gtcacgcaca cactgtaact ggtcttccag atgcatactc acgcggacgt
     9121 atcatcggtg tttacgcacg tcttgctctt tacggtgcag actacttgat gcaagaaaaa
     9181 gtaaatgact ggaatgcaat caaagaaatc gatgaagaaa caatccgtct tcgtgaagaa
     9241 gtaaaccttc aataccaagc attgcaacaa gttgttcgcc tgggtgacct ttacggggtt
     9301 gatgttcgca aaccagcgat gaacgtgaaa gaagcaatcc aatgggttaa cattgctttc
     9361 atggctgtct gccgtgtgat taacggtgct gctacatctc taggtcgtgt accaatcgta
     9421 ttggacatct ttgcagaacg tgaccttgct cgtggtacat ttactgaatc agaaatccaa
     9481 gaattcgttg atgatttcgt tatgaaactt cgtacagtta aatttgctcg tacaaaagct
     9541 tatgaccaat tgtactcagg tgacccaacc tttatcacaa cttctatggc tggtatgggt
     9601 aacgacggtc gtcaccgtgt tactaagatg gactaccgtt tcttgaacac tcttgacaac
     9661 atcggtaact caccagaacc aaacttgaca gttctttgga ctgacaaatt gccatacaac
     9721 ttccgtcgct actgtatgca catgagccac aaacactctt ctatccaata cgaaggtgta
     9781 acaacaatgg ctaaagacgg atatggtgaa atgagctgta tctcatgctg tgtgtctcca
     9841 cttgatccag aaaatgaaga acaacgccac aacatccagt acttcggtgc tcgtgtaaac
     9901 gttcttaaag cccttcttac tggtttgaat ggtggttacg acgatgttca caaagactac
     9961 aaagtatttg atatcgaacc aatccgtgac gaagttcttg aattcgaatc agttaaagcg
    10021 aactttgaaa aatctcttga ctggttgact gacacttacg tagatgcctt gaacatcatc
    10081 cactacatga ctgataggta caactacgaa gctgttcaaa tggccttctt gccaactaaa
    10141 caacgtgcca acatgggatt cggtatctgt ggatttgcta acactgttga tacattgtca
    10201 gctatcaaat acgctacagt taaaccaatc cgtgacgaag atggctacat ctacgattac
    10261 gaaacaatcg gtgactaccc acgctggggt gaagatgacc cacgttcaaa cgaattggca
    10321 gaatggttga tcgaagctta cacaactcgt ctacgtagcc acaaactata caaagacgca
    10381 gaagctacag tatcactttt gacaatcaca tctaacgttg cttactctaa acaaactggt
    10441 aactcaccag ttcacaaagg tgtatacctc aacgaagatg gttctgtgaa cttgtctaaa
    10501 cttgaattct tctcaccagg tgctaaccca tctaacaaag ctaaaggtgg ttggttgcaa
    10561 aacttgaact cactttctag ccttgacttt agttatgcag ctgacggtat ctcattgact
    10621 acacaagtat cacctcgcgc tcttggtaag actcgtgatg aacaagttga taacttggta
    10681 acaatccttg atggttactt cgaaaacggt ggacaacacg ttaacttgaa cgttatggac
    10741 ttgaacgatg tttacgaaaa aattatgtca ggtgaagacg ttatcgtacg tatctctgga
    10801 tactgtgtaa atactaaata cctcactcca gaacaaaaaa ctgaattgac acaacgtgtc
    10861 ttccacgaag ttctttcaat ggatgatgcc ttggatgcat tgagctaatc aagtttttga
    10921 ataatgaaaa ggaaccctcg gtcaaacgac tgagggtttt gtgcttggga tagtatgagc
    10981 aattccttcg gcgcaatatg caatgttttt gggaaggaat agtggaccga atctgaaata
    11041 taatagattg aaactagaat agtacacctt tacttctaaa acattcttag aaatcgattt
    11101 gactgtcctg atcgatttgt cctattctta tttcatttta ctatagtccg ctgaaacggc
    11161 tcaaacagtg ctagaaattg actggaattc tctaagtgat ttgttccgat tttatttcat
    11221 ttcatcataa aaataagatg actggctaat tgacaatcat cttgtttgat actgttaata
    11281 aaattcgcga agtttatctt gattttcttt aaaaaatttt tctaaccaat ccataccata
    11341 agcataacta aaaccttcta atagaacaga gaggtcaata gtatcaaatc ccatgtcttt
    11401 taaatattta aaggtatcga atggtgaatg aaagtttttg tatttaataa ttgcaccaat
    11461 atcttgcaaa tcctgctctc tgatactcat catcttcatt cctaacacat actcaatagg
    11521 gactactaaa acggtcagat tctcaaatga gtacaaggat tcgcataaac ttaagggagg
    11581 ttgtttgttc atatttgctt tgcaacatga ttgttgagcc ataactcttc gtggatgtta
    11641 agattaaact gttttcctac acgagcaata atttcattga ttttctgatt ttggtcataa
    11701 aaagcatcaa catcttgtgt ggtacgtaaa ccatgatatt ctaagacata accataattg
    11761 ttaaagtcag attttcctga attaatttct tatttagggc ttggaagacc ggtttcattt
    11821 tatccatgtt tgtatttctc catcaatttt tgaacattgg ttaacttagc aggtttattt
    11881 aatgaaatca catatttatg agttggagta tgctcttgaa aggcatactt caagctaatt
    11941 ttttgaaaac gggttagttc tttggagtct agcaactttt ctacatcttg gtttgttaaa
    12001 taagaatagt cttcaaaaat aacttttcgc aaatagcgaa accaatggct tgcgttgaat
    12061 tgtgattgtt tggatgcctg tatcatataa tcgtaccaat ccattgtctt cctcctataa
    12121 aatttagttt atattattgt agtttatatt caaaaatgta gtttttctta attagctcgt
    12181 atctatagga tgatactgaa aatcttcttg ttgctttaaa tcacaatcga aaaattctgt
    12241 ttttcatctt agaaaagaat gtttagaaat gtaaaatgaa ccttttttct tatccgaaaa
    12301 ccttactaaa gtatataatt taggcagtca attctgtatg ataatgtttg tactatcgtc
    12361 gagtttttgc ttgattgcct aacgagataa attttagaag agttttcggt gtgatttgac
    12421 aagtttctga ctggaaggat agttacacta gtattgttta ttaaaatgag cagatagaga
    12481 aaatttggaa tctatttgct tattatcaat cgttttttta gcttatttgt cttagattgg
    12541 tatagaactg atctatggat taatcctctt gtatcttatc ctgttcctaa atatgttggt
    12601 agaaaaatga agcagttgtt acgagtgtct gtattgggaa aaattttgtc tatagaattc
    12661 tttaaatgat atgaaggcta ggaatgccaa aacactgaca tatttcgttt aaagtctatc
    12721 cagtctcttc aattgtattt gtagaaatgc tatcagtaat atattcgcga acactatgat
    12781 ttacaacagt gtggtcgtac atctttgtaa ctttattata caacaaccac ttacaggtgt
    12841 aaagttgagc agtgtcttta gtaaatttag ggacttgttt tgtcatagtt ttgatacctg
    12901 tattcgttgt ttcatgagca tttgacgttt cttttcatgt aggcatttca acaattagaa
    12961 tgatattttt ccgaggatga acttatatat tgtgactttt tagagttatg atgcctcttg
    13021 atttgactat cgctatcaat ttcattcact tttacagttt catggtttta tgaaccgaaa
    13081 catctaggta caggttttag catcaattga ttgtttttga gccatatgaa gttgaaacgt
    13141 ggagatgctt ttcttgtgat aacgccctat tcaaagagga ataaccgttt ttggagagag
    13201 ttcagtacta tgtggcgcta aatactatat gtaaaac
//
LOCUS       DAVKBK010000046        13116 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVKBK010000046 DAVKBK010000000
VERSION     DAVKBK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.046"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            122..304
                     /locus_tag="VWX69_001516"
     CDS             122..304
                     /locus_tag="VWX69_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU9192834.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            249..960
                     /locus_tag="VWX69_001517"
                     /pseudo
     CDS             249..960
                     /locus_tag="VWX69_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1030..1392)
                     /locus_tag="VWX69_001518"
     CDS             complement(1030..1392)
                     /locus_tag="VWX69_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192835.1"
                     /translation="MPKTKTLAELADVILWGFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(1770..3650)
                     /locus_tag="VWX69_001519"
     CDS             complement(1770..3650)
                     /locus_tag="VWX69_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9192836.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVMGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3644..4513)
                     /locus_tag="VWX69_001520"
     CDS             complement(3644..4513)
                     /locus_tag="VWX69_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9192837.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLYRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(4597..7242)
                     /locus_tag="VWX69_001521"
     CDS             complement(4597..7242)
                     /locus_tag="VWX69_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU9192838.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(7333..8613)
                     /locus_tag="VWX69_001522"
     CDS             complement(7333..8613)
                     /locus_tag="VWX69_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU9192839.1"
                     /translation="MIYPKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            8784..10868
                     /locus_tag="VWX69_001523"
     CDS             8784..10868
                     /locus_tag="VWX69_001523"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU9192840.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKILVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(10908..12587)
                     /locus_tag="VWX69_001524"
     CDS             complement(10908..12587)
                     /locus_tag="VWX69_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU9192841.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQQVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLYFYLNLTVDGQLVDQLQVQVS"
BASE COUNT         3651 a         3111 c         2649 g         3705 t
ORIGIN      
        1 gaaattaaag cgggttaaaa aagaaattaa ctgagtaaaa actctcgaaa ttcaattcgc
       61 tatattatca ctcaacttga acaaatacca gaaccacaaa aaacagatgt aaaggaaaaa
      121 tatggactta aaatttgaag gggttgattt agaatacaaa aaagctaaaa acaatcttcc
      181 agagtctttc tgggaaacct actcagcatt tgcaaataca aatggcggga aaataattct
      241 cggtatagat gaaaaaaaca ttgacaccta ccaaagagtc aatagactcc ctgcgaaatt
      301 atgaagcaag taaacaatta actgatacac gatttaagcg tcttgttggt gttcagcgta
      361 ccacttttaa agagatgtta gctgtgttaa aaacagatta tcaacttaaa cacgcaaaag
      421 gtggacgaaa acctaaatta agcctagaag accttcttat ggccactctt caatatgtgc
      481 gagaataccg cacttatgaa gaaattgcgg ctgattttgg tattcacgaa agcaacttaa
      541 tccgtcggag ccaatgggtt gaagtaactc ttgttcaaag tggtgttacg atttcaagaa
      601 ctcctctcag ttctgaggac acggtaatga ttgatgcgac ggaagtacaa atcaatcgcc
      661 ctaaaaaaac aattagcgaa tcattctggt aaaatcttgg ctgacagtga ttatcaaggg
      721 ctcatgaaga tatatcctca agcacaaact ccacgtaaat ccagcaaact caagccgcta
      781 acagttgaag ataaagcctg taaccatgcg ctatctaagg agagaagcaa ggttgagaac
      841 atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa cctatcgaaa tcatcgtaaa
      901 cgcttcggat tacgaatgaa tttgagtgct ggtattatca atcatgaatt aggattctag
      961 ttttgcagga agtctattga aatactaagc ctacacagac tgattccaat tgttttttag
     1021 atttcaattt taccattctt catagtcaaa accatcataa tctggatatt gttctggcga
     1081 cgttccaacc gaacgtacga gataagcttc ttcgtcctct gtctcgattt ctctcagtac
     1141 ttggcattca aaacgccatt catcaccgaa gtcgaaaata aacttaaatt tttgtttgac
     1201 acttaggcta tccagataga cattttctgt gtaacgttct tcaacatcgt cactaacaaa
     1261 gctaagaaag taagaatctg catgactcca ctcaacatta tccatgaaaa atgcgtgagc
     1321 atgatcattt gcaaaatcaa aaccccataa aatcacatct gctagttccg ctaacgtttt
     1381 tgtttttgga atctatatat gtcggtagca acctttttta aatttgacgg aaatgatcca
     1441 agcttctaca gatgctggct tttcagcttc tatttcttgt tttactaatt ttaagtgtag
     1501 cataatacct ccaattgctc atcgatagaa ttgctcttag gaaacattca ctttctgcta
     1561 ttttatcata agtttgtcta actgtagcat ttgaaaccag ataattcttc tgtttcacgc
     1621 gaaacaccct gcgccaagca aggtgttctt gtttttatac tcaatgaaaa tcaaagagca
     1681 aactaggaag ctagctgcag gctgctcaaa acactgtttt gaggttgtag atggaagctg
     1741 acgtggtttg aagagatttt cgaagagtat taagtcgtat aaatcgtcga agctgtcgca
     1801 atggtatgcc actggttagc tgtagttgct gcgaaatcct tgtctgcgta gaagtcagta
     1861 aatggtagga tttcaacttc cagctcgtcg atgcggtcaa gctggccagc cagataaacc
     1921 tcgatacggc tttctgctcg tttgatgcgt tgcaagagtc cgcccatacg gatgtcaact
     1981 gtatccaaac caaagacctt gttttctttc aaccattggt gactaaagag ggcatggaag
     2041 tcttcaattt ggcttctaag ttctggtaat tcttgtctgg cgatttgttg taaactttct
     2101 ttatcatccg cttggtaggc ctgacgaatg cgtcgtccca catctacttt gctacttaaa
     2161 atagcattca actgggcctg agtttcaaag agataagcat agtttccagc tttttcttta
     2221 atgtcagcaa tagttcccgc cgcctgagcg aagtgtggct tgtcctgttc aggtgtcatg
     2281 tgtcggtcaa gtatcggaca gagaacatcc tgataaaaga catagcggtt gggattgatg
     2341 ccactgagat tacctggtag gtctggtaag aggttggcaa ggtcaatctg cataaaatcc
     2401 tcaaccgtta gaccagtatt ggtcttgaaa tgcgcagaca aactatctag gtcattgcga
     2461 tagctgagtt ctgcccagat ttgcaagctt ggtaggatag agaactgggc agtttcacca
     2521 ccattgtctc cccaacccat tacgatgact tctttaatct gattggcacg gcaggcttta
     2581 ttagcctcga tagccactag acggctaaaa tggttgtgag gtgtaaagcc aatccacttc
     2641 caagctcccc ctgcaaatgc aaggtcatgg ctaatcttgt gatgattgcg gaaattacgg
     2701 ttgtattttt cctcgctatc ctgataataa tcccagtaaa ccagagtcac acggtctttg
     2761 agacggtcta ggtagacacg agtttcctct ggaatttcca catcacgatc gtactggcca
     2821 tccgctgaca tgagtttgaa gaacatatca ctccacatct ggcagtggaa accatatttg
     2881 tcagcaatat ccagcacgcg ctccaagtgt tggcacatga ggagactacg atccacaaca
     2941 ccgttcaaaa tcaggtagcg tcccaaacca accaagtggg cttcgtccat cccgatattg
     3001 accttgcgag tcttcagttt agacaacgtg gcaaacatgc catcaatcag gtcataaacc
     3061 ttttcttcgc caatgagaag aatgtcctct acatcacgga gctcctgcac ttccttgaca
     3121 ccccatttga caaaggccga caagtgggcc aaggtctgga tgcatggtac aaaggtcatg
     3181 tcaaactgtt gagcataggc ttcgatttcc tgcaactcct ctgctgaata agctccacgg
     3241 aaatagccaa agtaaggctg tccttcaatc tggtaagtgt cttccatgta aagctcaaag
     3301 gttgagtagc ccatgagagc caagacctca atcatctgct tggcagaagc cacattcagc
     3361 accgcatttc gagaacagtc aaccatgtaa gccaaatctt cgtaagctgc ttgttcctca
     3421 atctctactt tatcagcttc tgctagaact gttaccaaca aggataaggc acgataaagt
     3481 tggtgaggtt tgcggtaggt caattgatag tgaccttcct caccctcgat agagatagag
     3541 gcttggtcag actgagtgac agccacttcc acatctggta gagaaatgtg accttttaaa
     3601 acctcaatag cttgcgtttg tttgggacta agtcctgtaa atcttaccat tgcttttcct
     3661 cctgtagcca gttgacaagg gcaccgtaga gattggcatc tgcgtgatag gtgcaggcct
     3721 ggataactgg tgcgaccgtg tattcttcgt aggcatcgac aaagtcttca acagccttct
     3781 taacaccttg gataaaatct ggattttgac tgatagagcc acccagactg atgacatctg
     3841 gatcgatcag atactggata ttgagcaagc cttgcgtcag attgcggttc atgcgctcaa
     3901 tggcttcttg acaaagagca ttaccagctg cggcctcttg gtaaatcttg cgaccgtccc
     3961 aatcagtatg accagatttt tcaatcacgt atcgtaccat attcccagtt gatgctagtt
     4021 gcgaccagtt attaagtttt tcagcagggg caagggttgt catgtagcca aattctccac
     4081 ccagaccgtg gcgacctcga taaagtctac cattgataat catggctccg ccaatccctg
     4141 tcccaatcac gacacaggct gcattttcaa gctctggatg agctagtagt tcactgagtc
     4201 caacgcagtt ggcatcattt tctaaatgga caggtagctg ataagagcta agcgcctcat
     4261 accaagaaaa gccatggatg tagggcaccg cactgaagcc atcaatcaca cctgtctctt
     4321 gattgaccgc acctggaacg ctcatagcaa tcccactgta atcctgttct gacaagcgtt
     4381 gatctagcca cgctagtaaa tcctccaagt tttcaggcgt tgaaatactt gtcttatcca
     4441 gtattttccc atcaggagtc agactggcaa acttaatccc agtccctccg atatcaatcg
     4501 ttgcaatggt cattgttttt accataaaaa ggggcgaatc agcagttagt tcttactttt
     4561 tcgcccctcc tttcttttga tgtttacttt ttgaaattaa atttcttctt ttttgatgaa
     4621 ttctgtacga atctcttgtg gagccaatag tcctgaatga actggatatg gtcgctcaag
     4681 taagtcaaga atggtttgtt gatgttctga tatgcgcaca ttttcttgac tcatattata
     4741 gtaacggagg acatagcctt cttcattttc cgccacttta aaggctgttg gacaaacttg
     4801 cggtatgctg agaacagaat ggctcaagag gctaccagtc gcaaccacgc ttccttcctg
     4861 tctagcaagc tgaaggctgg taaacggtgt ctgcaaggct ttggcacgac gataggctga
     4921 gaagcgttct tgggcttggt ggcattcaat cgcaaattcg acttcaaact cacgcaagca
     4981 ttgtgcttct ggcgttggga agtagcccca gtcacctagc tcacctgatg cacgcaaaat
     5041 ggtcacggca atggtgttat ccccaaggat ttcgtattca ttcaatccct tgttggatac
     5101 agtcacccct ttttcatcgt catacagact gacaaaagct tgttggtgtt gaggattttc
     5161 aggattttcc catgaagcag ctggtttgtt tggtcgtgtc accacctcat agatactttc
     5221 agaatcattg cttggacgcg tgttatgagt cttgaccaag agacggatac ggtgatcctt
     5281 ggcagtgtta gtaaagcgag tcttgaagcg gatttgtgga ttgtcaacaa agacaatcaa
     5341 ctcagtttcc agaggaatgt ttgtcaattc ttctgaccgt ccagcctcac gcttcataaa
     5401 ctcgatgata ccttgttgct cttcttctag cttttcatcc gcactgacag gcacggtcaa
     5461 ttcatgtttg agcaagattt tagcatagcg atctgtgttt tccaagacct cgtggccctt
     5521 aagctctgca aagattggct ctgttccttt tggttggaaa tagatatact cgtttccgat
     5581 gtcaccccgg tcttcgaagc ggataaaatc ttcataggct tcgtgagttg tcttatcata
     5641 gactgtgatg ttgtcatcca cactcaccgt tacgaatggt gtatcaatca ctccgttttg
     5701 gtaaataccc tcacggtgtt cttgttctcc ttccagcaat tggaaggttg tccaagaaag
     5761 cggtgctagg tgaactggaa tggtcacgcg cacttgtcga gcaatacgag cttggcggaa
     5821 cttatctttt ggtaaatcgt attcaaaatt agctccgagg tcttcgattg taacctctac
     5881 aggacgacca tccaagtcct ccacacggta acttggcaag ataagagcag ccatcttttt
     5941 gtagccttct gttgggtgca attccttgaa atcacaagtc gccacatcaa tcactgtgct
     6001 gacagtatcg accttatcat gcaagcctgt gttaatgaca gtaaagagat agtcactttg
     6061 agccttatcc gtagcaattt tacccttcca ctcgttgagc aaattacttt taacaaagtt
     6121 tcctacttgg ttgaccttgg caaaacgcgt ttccatctcg cggtgaactt cgtccacgct
     6181 acagccacag atactatcat gtggcgcatt ctgcaaaagt gttttccaag cataggtcaa
     6241 ctggtccttg tggttgtgtc caccagtgat aatagtcaag ggttctacca cttgctctag
     6301 gaggttgcta ttttcttgga aggcttgttt taggtaaatg cgggatgaag aagtgttggc
     6361 aagtgtgtac cagccatctg tttcctgact ggtcaactcg cctgtaacag ttgataagtg
     6421 ttcaggaagc gcaccttcta cagcttgaac atattcatca aaagaactat gaacaaagat
     6481 tacatccggg aagagttcat ttgccacacg aatggcttcg ctcagatttt tctgtacagg
     6541 ctggtggtca cagccgttca tcatcaacca ttggttggtc gaagcgtagg cacgcacatc
     6601 tgacaatttt tgtttccaga aggtcaaggc ctcatctttg tcaactggga tttcattccc
     6661 attactgtac cagttggcaa agagaatacc taaaacacga ctaccatcca caccctgcca
     6721 gtacatttct gaaaactggg atgtaaactg ctcatcttca aggacttggt tgtcaaatcc
     6781 aatcggcttc acaccacgac caaaggccgc cacgtgaatg cctgattttt gaagaatttg
     6841 aggcgcttgt cccatatttc caaaggtatc tggaaagtag ccaatctggg ttgatttacc
     6901 ccatttggca gcttcttgtt gaccaatcaa ggtattgcgg acattggctt cactggagat
     6961 caagtagtca tcctgcaaga tgtaaaaggg accaatttta agtttgccct cgtcaatgta
     7021 gcgttggacc ttgtcgcgat tttcagggcg aatttgtaag tagtcatcaa ggacaatagt
     7081 ttgtccatcc aagtggaaac tcttgaactc agggtcattt tcaaagagat caaagagatt
     7141 gtcaaacaat tccaccaact gcatacgatg gctttcaaaa ggcaagtacc actcacggtc
     7201 ccagtgacta tgtgagataa tatgtacaac aacattttcc atgaagtaaa acctcattct
     7261 aaatttaaat tttaacgttt taaatgtaaa cttgtgattc tgataagaat cggttgagct
     7321 aaagcgagcc ccttagcgaa tatccaagta atccaagacc aactcacaga acatcatgtt
     7381 agcccaggag aaccattcac gagagtagag ggtcggatca tctacgtgga agctttcgtg
     7441 catgacacct gtaccaccat cgcaggcaac cagctgatcc agcaagaatt ttttctctgc
     7501 cttatctctt gttgtcaatc cttggataga aagggcgatt ggccagatat agcgatagaa
     7561 ggtatgagaa cttccgagac cgctagcgta ttctccttgg tagaagtatg gattttcaga
     7621 gctcagaatg gtacggcgag tggcttgata cacttcatca tcgatcgaac agtagcccag
     7681 atagggcgca gctagtagac ttggtacatt tggatcatcc atgatgctgg catttcctag
     7741 gccatctact tcaaaagcgt aaatcttttc gcccttgctg ttggtggtgt aagcgtagtt
     7801 ttcgattcct tcttggattt catcctgaag acgcttggca tcagcaataa cactctggct
     7861 atcagctagg tttaatgctg cgaagatttc ttgcacataa cccaagacta ctacagcaaa
     7921 catatttgac ggaatcaagt aactatactg gcaacagtca tcactcggac gaaaggctga
     7981 ccaagtcata cctgtcactg caaagtcagg tccaaagcca tcatttacca aggtgtcttc
     8041 cttacggtcc gtatctcgga caaaacgata aggagagttc ttgtggtctt gttcaactgt
     8101 ccatagatgg agaatttcct tagtcgctgc gacaaaagtc tcatcaaact gactagtctc
     8161 gccagtttct ttccagagga gataagccaa ctgcaaagga tagcaaagcg agtccacctc
     8221 atacttgcgt tcccaaatcc agccattaag gtcggtgtgg tcggtctcgt ggtgcccctt
     8281 ccagttttcc tctatgttga aggaattggc ataaggatcc ttgagtacca aggtcatctg
     8341 acgtttgacc aaacctgcaa tggtctgacg caggagggca tctcttttag ctacatgcag
     8401 gtagggtctg agttgggctg tcgaatcccg aagccacata gcaggaatat ccccagtcaa
     8461 gacaaaagtt gaaccatctt ctaagatttc aaccgtattg tccaaggtat cggtgtagca
     8521 acgctcgaaa acatccaccc actctggatg gtccttagcc cgctctgcta cttcatctag
     8581 ccattctcta acaatttctt tcggataaat catcgtgcaa ttccctcttt caaacaagtt
     8641 tcatgttcag tatatagctt ttgagacaga aaatacatac acaaatgata gtcatttttc
     8701 tacaaaatag ttatttttga aactcctttt ctaaaggccc tctttttctg atataatgta
     8761 gaaaaacagc taaaggaaag actatgaaac cactacttga aaccatcgat acccgctttg
     8821 gtactgctag caagcatgcc ttctcttggg gaaataccct gccatacaca ggcgtgcctt
     8881 ttgggatgaa ttactttgtg ccccagacca gtgaccagga tggatcttgg ttttttgatc
     8941 cgcatctgcc tatctttcag gggattcgat taactcacca gcccagtcct tggattgggg
     9001 actactcttg gctccttctg acacctgtca ccagtcaact ggggggagac agcctctttc
     9061 accgccagtc ttcttatgat atagataaag cttgcttcca gcctcactat ttgaagctct
     9121 tttctctgcg ttatcagatt gaaacccagc tcacaccaac ttgctatggt gcttctattc
     9181 gtttgaatca aaagcaaggc aaagccctct ccctctatct tcacgcagca gatgaactga
     9241 cagtagagca agtagataag cggactcttg ccctgcgaca agaaggtaaa actgaaacta
     9301 acaaaaattc gctaacgatg ttcactgccc tgcaaatgaa cacggatatt cttgctatca
     9361 gccaagaagc tggagactgg cgaattgact tagtaagtag tcaaaccgag atgcaactag
     9421 ccacttcttt catctctcct tctcaagctc taatcaatct acctcaagaa gattttgata
     9481 gctgtaaatc aagtgcccaa gcggattggg aaaatctcct ccatcgtttt gacattatag
     9541 agacaggaga ggctgaccga accttctttg accactgcct ctacagactc ttcctcttcc
     9601 cacagacttt ttatgaggtt gatgagtcag ggcaagccat ccacatggat ctggctactg
     9661 gtactgtcaa gcctggtgtc ctctttagca acaatggttt ctgggatacc ttccgcacca
     9721 ccttccccct ctttgccctt atcataccgg agcactatca acgcttttta gaaggtttcc
     9781 tcaatagcta ccgcgatact ggtttccttc caaaatggct ggctccagat gaacggggta
     9841 tgatgccagg tacactttta gacggtatta tcgcagatag cgcctgcaag gacatggccc
     9901 ctgacctaga aggagaactc ttccaagcca tgctcgaaac agccagcaaa gccgaccctc
     9961 tcggcatcaa tggccgccac ggactagccc aataccaaga actaggttac ctctctaccg
    10021 accaccatga aagtgttagc catactctag actatgccta tagtgacttt tgtatcgcca
    10081 gctgtgccaa aaaactagag aacatagaaa tcgctgaaac ctacaaggct gcttcacaaa
    10141 attaccgcca gctatttgac gctgagacag gttacatgcg agcacgagac aatcaaggaa
    10201 actttcaccc tgacttctct ccttatagtt gggggcgaga ctacgctgaa tgctctgcca
    10261 ttcaagctac tttaggcgtt ctccacgaca tccctggctt aatccaactg atgggtggaa
    10321 aagaaacctt tagcaactat cttttgaaag cctgtcaaga tgctcccctc tttgaaacaa
    10381 caggctatgg ttacgaaatt cacgaaatga gcgagatggc tactgctcct tttggacaaa
    10441 tagccatttc caaccagcct agtttccaca ttccttatct cttccgctac agcgattacc
    10501 ctgactacac tgcccttctt atcaagacgc tccgtcagaa agcttttcac ccaagttggg
    10561 aagcctatcc tggagatgaa gacaatggta gtctctctgc ttggtacatc tggtcagctc
    10621 tcggatttta tccaacctgt ccaggaaaac caagctatga cctcggaatc cctctctttg
    10681 accatctacg agtctaccta gctaaagaag ataaatggct ggatatccat actaaacaaa
    10741 accacaacca ttttaacttt gtcaaagaat gccgactgga caaaatactc gtatcaacta
    10801 ttcaacacca agacctctta aaagctgaac aactaacttt caccctcagc tggttaccaa
    10861 gtcactaata accaaaagaa cctttgcatc gcgcaaaggt tcttctttta tgaaacttgg
    10921 acttgaagtt gatccacaag ctgaccatcc accgttaggt tcagatagaa atacaaggtt
    10981 ttatctcctg cgaaatacaa ggttggtagc gtcagacttt tttcagtctc accagcttga
    11041 aacgcaagga cttgaatctc atcctgatag gcgacaccat ggacacctgt ccccggttga
    11101 atcgaaatct tagcttctaa aggaccacta cattctctgc gcttaactgt aaaataggca
    11161 ttttctccct ttgccacagc taggcttttt tctgcaaatg ctagttcctg aacaacttct
    11221 ttttttgata atccaggagt tttataaagg gaaatcttgg tcaatacagg aatagattgt
    11281 gcctcggtaa tcatcacgcg caccttctgt gcctctacta gcggacctcg caagaggcgc
    11341 ttatgaccaa ctgtgaagcc cctgccaaat tcctgccaga caccatccac ctctacttgc
    11401 acatgaaaag cagcgattcg ttgccctagc ttcaaatctt ctcttaactc aattacatca
    11461 aaagttttag gagaacctaa gtcgagttct aactggatgg gcaagtctgc atcgtttgcc
    11521 caagagctgg tctcaaggcc gtctgtcaaa tggcgacaag caaagtctgc ggaaagagct
    11581 ggaccagata cctcagctcc cagagccaaa tcttctttat agagctcatt gcgataggtc
    11641 gcaaattcat aaagtcgttc aatatccttt gcatcaaaga gcccagcttg attcggcgga
    11701 atattaagca agagtggagt tcctcgccct actgagtgaa agtagatttc gaccaactcc
    11761 tcgagagact taggatcctg atcctcatgg tagaaccagc ctggacggat ggaaacatct
    11821 gcctctccga ttgaaaaaat cgtgcccgag ggatccccgt gctgaagata gtccagctct
    11881 gcttctgttc ctagtttatc aggattcacc ttttgccaca gtggatcacc tgcataccct
    11941 cgttcattgc caatccagcg gatactggtg ccttctgttg aaaaaatcaa acaatcgccc
    12001 tgcaagtcac gaatggtttc aaaccatttt tcaaattcat aattgacctg ctgggcccct
    12061 tcccctctag caccatccat ccaaacctca gcgaacttac cagcattccc atagttagga
    12121 tttgataaga tttccttcaa ctgagccaga taataggcat tgtagtccgc ttctcggtcc
    12181 acatgataga ggggactatg ggcatcccac ggtgacaggt agacccccat atccatatca
    12241 aactctgtgg cagcttggga tacttcaagg agcaagtcgc cctttcctct cctccaagga
    12301 ctgaccttaa ccgaataatc tgtgtgagct gtcggataaa ggacaaagcc atcgtggtgc
    12361 ttgaccacca aaatcaactt tttgaagccc gtttccttga gcacacgaac ccactcacgc
    12421 gcatccaact gactcgggtt aaagcgctca ggatcctcct gacctgttcc ccattcctga
    12481 ttataaaaag tattaggtcc aaaatggata aaggctgcta gttcatctcc cagataagct
    12541 agctgagtct gacttggtaa cggtccatgc ggtttgattt tcttcatcgt tatatatctc
    12601 cttcttttgc aacttctctt gttcacaagg ttatccacag gttgtggata ataaaccatg
    12661 atctaacagc cagctctttc caactccaac tggtaggctc aggatttttc tcctcaatat
    12721 tccctcttca aacagctctg tcatatggtt ctgctaacac ctctcagaat gctactctcc
    12781 ataattattc tcaggcttct ttcaggtcat tgtgtgaaga ccattcactc tccagacttt
    12841 tccacagatt gtgaataagt gattattcta aactatcacc tcgtcgacta taacaaaaaa
    12901 taaaaagagg gtcaataaga taattatctc ttcctaaata ctcagaaaag attctataat
    12961 ttgtacaatt gaacaagaaa tgcttctcca aaatctatct tcaaaagaat gttgcatctt
    13021 tttatccttt cacacaaaca tttctcttta tacagatcca agtgataacc agatgataat
    13081 tggacacttt ttggttattt gtgtattttt tgaaaa
//
LOCUS       DAVKBK010000047        12785 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVKBK010000047 DAVKBK010000000
VERSION     DAVKBK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.047"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(415..2142)
                     /gene="ezrA"
                     /locus_tag="VWX69_001525"
     CDS             complement(415..2142)
                     /gene="ezrA"
                     /locus_tag="VWX69_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU9192842.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2224..4170)
                     /gene="gyrB"
                     /locus_tag="VWX69_001526"
     CDS             complement(2224..4170)
                     /gene="gyrB"
                     /locus_tag="VWX69_001526"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU9192843.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4185..4748)
                     /locus_tag="VWX69_001527"
     CDS             complement(4185..4748)
                     /locus_tag="VWX69_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9192844.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4833..5387)
                     /locus_tag="VWX69_001528"
     CDS             complement(4833..5387)
                     /locus_tag="VWX69_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU9192845.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5398..6621)
                     /locus_tag="VWX69_001529"
     CDS             complement(5398..6621)
                     /locus_tag="VWX69_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9192846.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6658..9108)
                     /locus_tag="VWX69_001530"
     CDS             complement(6658..9108)
                     /locus_tag="VWX69_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU9192847.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPFSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9308..10237)
                     /locus_tag="VWX69_001531"
     CDS             complement(9308..10237)
                     /locus_tag="VWX69_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9192848.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10377..10664
                     /locus_tag="VWX69_001532"
     CDS             10377..10664
                     /locus_tag="VWX69_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU9192849.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10698..12032)
                     /gene="ciaH"
                     /locus_tag="VWX69_001533"
     CDS             complement(10698..12032)
                     /gene="ciaH"
                     /locus_tag="VWX69_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU9192850.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12022..12696)
                     /gene="ciaR"
                     /locus_tag="VWX69_001534"
     CDS             complement(12022..12696)
                     /gene="ciaR"
                     /locus_tag="VWX69_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU9192851.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         3882 a         2731 c         2278 g         3894 t
ORIGIN      
        1 tatttaccgt ggactaaagt tgtacaagaa aagtgcaaat aagaaatctc cagattagga
       61 actatccgtg agttctctag tctggagatt tttcaataga cttcgttatt ggacggttac
      121 caagttactc aaagtacaga tttgaagctg cagataagac tgacgaaatc actttaatac
      181 taaatgaaaa tcaaaaagca aactaagaag ctagcctcag gctgtacttg agtacggtaa
      241 ggcgacgctg acgtgatttg aagagatttt cgaagagtat aaaacactgt tttgaggtgg
      301 tggataaatc ggctgggtaa aaactcaatc tcaggagaaa atgaagtaaa tctccccaca
      361 actatagaaa aagatttgat tctgctcctc acacaataaa atctttttct tttattaaaa
      421 acgaatcgtt tcacgtgttt tctcatatga ggtaacaaag cgattggtta caccaggctc
      481 tgccacttcc aatgcttgag aaatcttgtc aaatgaagcg tgataatcaa attctttttc
      541 aaaaatatct aaagcttcgt taaatgcttc ttgaatgcgt tcatcaaatg agcgatagcg
      601 gttagaatat tgcaagagtt gctctgtcaa agttgcatat tgtacaatat tataagtttc
      661 cgtttctaaa gcttccatat cattcgttgc aatttcaaga actcgggtaa cagattcaat
      721 gttaatcatt ttttgttcta actcaaccat taaatcctcg gtattattgc ttgccgtaaa
      781 gaataacttc aagaaagttt gtggaatacc tggcagattg cgtttttcca tgtatcgctt
      841 gatagtatgg agacgattga cataaacatt ggccttttga cgtgcattaa tatcatcttt
      901 ctcaatttgt gtcaggcgct cactaactga aatttgctca tcttcaatat cttttagttg
      961 agtttgtaaa tcctcaagat tttcttcaag aactgaataa gcttgggttg gttcttcttg
     1021 atttgaagtt acctcaacaa tagctgcctc aaaactctct aattctgtct gaatacgacg
     1081 aacatggctt gcagctgtct caggaagtaa ataggtcttg ttcaaacgtg caatatcttc
     1141 tcccaataaa gtattattct ctttcatatg ttgaaggtaa gttggaagag ttgcaagtag
     1201 attttccact actttctgag cagcaatttc tcgagtaaaa atatcataca aggcattgat
     1261 ttcctcttgt gcctgtccat tctcatattc ggcattatcc aattccaact gacgaatatt
     1321 ctcttggttt ttcttgaatg cttcataaag caagtggaaa cgcgcttcaa tatccgtttc
     1381 aacaaaatga taattagcat caattagttt acgataaccg gattccaaat cctgtaattg
     1441 atctggcaat tctgtagaaa gcgtcgtaac caaggctgga acacgatcca caatatgact
     1501 taaggccaaa atgtgatttt ctgtattatc caaaatcact gcggcttcca cagggtcacc
     1561 cgatgaattc aaggttacaa attgtgaaaa ttcagattgg atattttcta attgtttttc
     1621 aatttcatcc aaggcttgac catactgttc tgaattttca gcaactctat gctgaagttc
     1681 ctcaaataaa tccaaagcat gaagaacacg accactattt ttagattctt gcttctctaa
     1741 gtctgccaaa gcattgcgaa ttgccgcaat atcttcgtca atcaaagtaa tttgactctc
     1801 aatttggtca atttgatgac tggccttgag aaaacgaaat gaatggttat agccttctgc
     1861 ttcaaagaga ttattttcaa tatcggcaaa agagttgaga gataaatcga cccatttttg
     1921 attccattca cggaaagcca cttgactttg tccaatcaag tgcatatttt ttacagcttc
     1981 tacttcatca tttactggaa gattgtatag ttcttctttt ctttcttcta gcgcctctaa
     2041 tctcccctcg tttcgcttac gtagaaagat tgccactaca taagccagaa ctaaaatgac
     2101 tgcaattgca accattaaat aaattagttg tccattagac atatcaaact ccttttttac
     2161 ttgaaacaat cgtaacgatt atatcatatt ttttagacca agggaactac ttctccctat
     2221 tttttagaca tcaagtgtac tatagacagc attttcttcg ataaactcac gacgaggctc
     2281 tactcgatcc cccatcaaca tatcaaagat tttatctgct tctgcagcat catctacaga
     2341 aactctagcc atcaagcgat gttcgggatc catggttgtt tcccacagct gatgatcgtc
     2401 catttcacct agccccttat aacgctgaat agtcggtttg gtacgacctt cactataacg
     2461 ggctaaagct tcttggagtt tgatttcttg atctgcaccc ggctggatat attctttaat
     2521 ctcgcttcca accttgacac catagattgg tggttgggca atataaacat aaccagcttc
     2581 taggattggt ttcatataac gataaatcaa ggttaaaaga agggtacgaa tgtgggctcc
     2641 atcgacatcg gcatcggtca tcaaaacgag tttttggtaa cgggctttcg aaacatcaaa
     2701 ttctgcgcca aatcctgttc ccatggctgt gaaaagacta cgaatttctt cgttagctag
     2761 aatcttatcc atacttgctt tttcaacgtt caaaatctta ccgcgaattg gaaggatagc
     2821 ctgaaactca cggttacgac cagatttggc tgatccacca gctgagtctc cttcgacgat
     2881 gaagagttct gtttcagcag ggttattaga agaacagtct gctagtttcc ctggaaggtt
     2941 ggaaatttcc aaaccagatt ttttacgtgt gacttcacgc gcacgcttgg cagccacacg
     3001 agccttggca gctaaaatcc ctttttccac gatacgtttg gcaatctgtg gattttccat
     3061 gaggaaatcg gagaaggctt cactgaagag gcgattggta atcttgacca cttcgctatt
     3121 tcccaatttg gtcttggttt gtccttcaaa ctgtggattt gggtgtttaa ctgagataac
     3181 tgcagttaat ccttcgcgaa catcttcccc tgttaaatta tcttcattgt ctttcagtaa
     3241 cttattctta cgagcataat cattgataac acgagtcagt gccgtacgga aaccttgttc
     3301 atgcgttcca ccttcatggg tatgaatatt attggcgaaa ctcatgacat tttcatggta
     3361 acctgttgtg tactgcatgg ctacctcaac tgtgatatca tccatctcac cgtctgtata
     3421 gattggtgta tcaaagatta catccttgtt ctcgttgata tattcaacgt aactagcaat
     3481 cccaccttca taatgataat gcttggtttg ttccaaacct tggcgcttat ctgtaattga
     3541 aatttgaaga ccgcgattta gaaaggccaa ctcttgaatc cgtttattta atttatcaaa
     3601 atcaaagatt gttgtttcag tgaaaatttc tgggtccggt gtgaagtgaa ccgttgttcc
     3661 agttctatct gtatccccaa ccacctcaag gtctgcaaca acatgaccac gacggtattc
     3721 ttggtaatga atcttaccgt ttttatggac atgaacgtct aattgagtgg aaagggcatt
     3781 aactactgac gaccccaccc cgtgaagacc acctgaaacc ttgtatccac caccgccgaa
     3841 ctttcctcca gcatgaagga ctgtaaagac ggtctcaaca gcaggacggc ctgttttttc
     3901 ctgaatatcg actgggatac cacgcccatc atccacaaca gtaatcgaat catctggctc
     3961 aataaaaact tgaatatggc tggcaaatcc tgccaaggcc tcgtcaattg agttatcaac
     4021 aatttcccag actagatggt gaagaccttc ttttgaggtt gatccaatgt acatccctgg
     4081 acgcatacga acagcctcta agccctctaa aacttgaatt tgactggcat cataatcctg
     4141 tgcctgcaga tttttgattt cttctgtcat cttattcctt tttcttatat gtctaatact
     4201 tgtcttaaat tcacgatact ggtaaacaag tgggtatcaa gtcctgcagc ttgacctgct
     4261 tcgatatcaa tcggccgatc accaatgaca agaccagagc taatctgata cttttctctt
     4321 aaataaagca tggattcggg atttggcttt ctcttaaagc ctgagctaga agtcaccact
     4381 tctgtaaaat aagctgctat agaggttttt tctaaaattt ccaaaacctg atcatttcga
     4441 tgagagacca aaaaatgacg gccaccttga tttaaaatgt cttccaatag gtcagaaact
     4501 ccttcaaata aaatcgggtg ttcaagctct ctggcttcat tttccttgta cttttctaaa
     4561 aaattctcta aattgggagc gaatgtctca atcgcaaaag gagtagaaac ctttaaagct
     4621 tgatagacac tgtcatggtc ttgtgtgata ccatacagtg ccaatgtttc aacaaatgca
     4681 gctgttgaag tttcataatt atccagtaaa gttccaccta aatcccagat gtaatcgtga
     4741 tatttcatac ccttcattat agcatttttt tatgaaaaaa gcgatgattt ccctgagttt
     4801 tccacataaa aaacgagaga ataactcccg ttttactgat ttttaccaaa gacatctcga
     4861 tagagcattc ctgttcgtaa actctctgcg tcccctccta gttgctccac caactcgtag
     4921 gcaaaggcaa gggctgttga aggaccccga ctggttgtca actgaccatc taccactact
     4981 gtttccttga cgtagtgacc atcaaggatt tgctcttgaa cgccgtcata acaagtgtat
     5041 cgcttatttt tcaatatctc tgcttgattg agggcaattg gtgccgcaca aatggctgct
     5101 agtttcttcc cttcttgctc gaagctttgc aattcttgaa tcaaggtctg attatcacgt
     5161 aaatgtgcag aaccaggcat acctccagga agaacaatca tatcatagtc tgataaatct
     5221 ccatcaaaga catgatctgc tcttacttgg attgcatgcg aacccgttac ttgctcttca
     5281 aaaccaacca tatcacatgt gatattggct cgacgcaaga catctacaac tgtcaaggct
     5341 tcaatttctt caaagccctg agctaacata actgctactt ttaccatgat tttctcctta
     5401 tttaatttgt tttaatacaa cctttttccg tttgaatggg acttttccgc tcttttcttc
     5461 agctaaatta gtctggtaac tcatcgataa aagcaaacca acaccaatca aattactgat
     5521 aatagctgat cccccttgcg aaatgaaagg caagggaatc cccgtcaaag gaagtagtcc
     5581 agtcacagca ccgatattct caaagatgtg gaagagcaac atcataatca aacctgtgga
     5641 aatataagtg tagaactggt tatttgattt aagagtaatc ttcaacatac ggtaaatcaa
     5701 catgagatag agggcaataa ccaggacaga gccaataaag ccaaaatctt ctgcaataac
     5761 cgtaaaaatc atatctgact ctcgaactgg gataagcaga ttcgaagcat taaatccctg
     5821 accaaataag ccaccactcc caatggcaat ctgcccttga gcctgctggt aagtcgttgt
     5881 ttgggcaaac tcaaagggat tgagccaagc caaaatccga ttaatttggt aggtcggcat
     5941 tccaatctgg tgaagaaaag ctcgtccgtc cttgctaata aagatagcta agaaaccagc
     6001 aactcctgtt acagcagtca caaatactgg gataataatt ttccaagaaa cccctgataa
     6061 taaaacgatt cctgagaaaa tggctacaaa aaccaaagcc gtccccaagt cactttgaag
     6121 tgctaaaaga actaggactg gaatggtaaa gagaatcatc cagaaaatta acaaaaagtc
     6181 cagcggaacc gtgcgtctcc attccttatg tttctttgta aattggacaa tgacacgagc
     6241 caacatgagg atataggata tcttcataaa ttctgacggt tgaaataggg taattccatt
     6301 tattgatacc cagtttttgg cacccgttga tgcaactaag cttggattat aaaatacaat
     6361 cggcaagatc ataagtccca agcctaaaat atatagaaag ggggtcacct tccaaagaaa
     6421 ttctgtatta aagagcatga ccacaaaacc aatcacaagc cccaaggcaa tccaggcgac
     6481 ctgctgccct aaaatgggca gaatattatt gggataatca tgactaacgg ctatatagat
     6541 agccaccaca ccgatgacca gtagaaaaaa tactggcaag agcaaactat aatcgactct
     6601 agagtcgaga gaacgtttca tatgtactaa ccttatactt tcatacaata ctatttatca
     6661 aagttcatta aaaaatctat caatagcctc gtcaacttcg gatcgagaga tggttttaac
     6721 agtcgcttct tctgctagag atgctactat ttgtttgccg tatcgttttc cgacgattct
     6781 cctatccaaa ataagagtta aggaacgttg gtattcacgt ctcatacttc ttcccaaagc
     6841 ctgttttaaa cgaataatgg ccattggcaa ttgataatca taaaaggcat ttttcccttc
     6901 ttgattcagt tcttgattaa tctttttcgt caagggttct tgaggatttt ggaaaggaag
     6961 cctcggtaca acttgaatca cagaaggatg gcttgaaaaa tcaactccct cccagaaact
     7021 tgctgcacca agcaagattt gttgttcacc tttttcaaag cgtttcttta gctgatgaac
     7081 atccccattt ttatactggg ccaagtggct aactgtaagt aaatccgata ctgctagaag
     7141 catgtcttta gcggtaaaga gaaccaaaat cggttgctgg aaagcttgaa tttccactag
     7201 taaagcagct acctctctgg catagacttc taaggaggtt tctgttacca gagggaaatc
     7261 tttgaccata accacttctt gttcctgttt tccccgagat tcaatcttga caaatttggc
     7321 ttcaggatag cctaaaaggt ctgccaaaga aaccctctga ctaatctcaa gagtagccga
     7381 tactcccaag acttggcaac tctcaggaag taaagaggac agaagagtac ggcctgattt
     7441 tgtagaagaa atctgaattt tcttttgact cgtttcagtt acttcaagcc agtaatcacc
     7501 ttcagctgta aaatagcgaa ccagctcatc aaagccttcc acttctaatt ctgaaaaata
     7561 ctgatggaga ttgtccagag aatctaagat atttttccta gatttaccag actgaaattg
     7621 ttctatcaag tagagacact caaagcgaat actttctagt atccgttgtt gaaccctgtt
     7681 ttcttctcct actaaagcct tatcaattaa atcgataata gattgtatat cgtaggtctc
     7741 ttgaagcaga ttttctagag ctaacaaaat cttttggact tcatcaataa tcagtaaacg
     7801 gtcactgaca aattcaggat tatcttcaag tctggtcacg agataggcat gattagtcac
     7861 taaaagcttg caagtctctg ccctttcttg actacgtttc caaaaatctt ccgtcacaaa
     7921 taagctctgg gatgataaat tcccatcatg acgaaggtct gctagaaaat gttggtaacg
     7981 gtagagttgc ccgatttcat ccaaatctcc tgtctctgtc tcagtaagcc agaccaagac
     8041 ttgcatttta aagcgtctaa ataagcgatt ttcatcattt tcctgcaagg aatgataaaa
     8101 ggcatccaac ttcagataat tttgtggtcc ctttaagcta tgaatatctg tatggaacac
     8161 ttccttgaga cgtttacctt cttcttccat gatttgattt tgaagaatct ttgtcggaac
     8221 actaagaaca atttgtcgct ctttggattg agataaagcg ggtaagagat agccataggt
     8281 tttcccaatc cctgtcggcg cttgaatcag agagaaaggt tcatctttca atagcaagcc
     8341 aacctcttta gcaaaacttt cttgttcctc cctcacttca aggttcaaca gagaaatatt
     8401 tttagaaaag tcttgagata gttttcgtag ctccagagaa gctgccgttt tcttaaaata
     8461 cagaccttga acttggacca agtctggaga actcaggata gattggttgc gataagtttc
     8521 ctcaataacc aggtaagact catataggag agcgtcagcc atttccagca agcgttccaa
     8581 gagaccttta ggaagctggg tcatcttttc ccgtaaaaaa agaagtaatt ctgctgtagc
     8641 ttgggcatct gaaagggctg tgtgtgcgtg tttaagagga attcctaatt ctcgacacaa
     8701 aatcggcaag ctatattttt ccagttcagg gaaaaagacc tgggccaatt cgaccgtatc
     8761 aacacgaggg tttcttagct catagccttc aaaaaataaa ttttccgcca agagattagc
     8821 atcaaactga acattatggg ctacaaaaat cccatcctcc accaagtcaa agatttttct
     8881 ggcaacttgc gaaaaatcag gtgcttgcgc cagacgttgg tctgtcaatc ctgtcagttc
     8941 tttgatatga gcatccaagg gttcatgtgg attgacatcc gtcgtatagt gatcgacgat
     9001 ttctccatcc tcaatcacga caattcccac ttggataatt ttagccttac tacctgtgct
     9061 agttgcctct aaatccacca caacatagcg attaccaatc gttttcatta taaaaaatta
     9121 taccaaaaaa agggccattt ggcacctgca aacataggat aattttcaaa ctcaagaaca
     9181 ctacttttct tagaaatccc atcgaataga gcattctagc ctgctgattt ttttaaaata
     9241 gtgaagaaat acgaaaaatt gagagaagaa atgttttcat cttccttctc tcaacgaatc
     9301 atgtatttta tttaaccatg tcaggatcgt agtcataaaa tcctgtatca aggaaacggt
     9361 ttttagggtg aagtttacga acttcttcat ccagcaagaa ggcttggtca tggctaaagt
     9421 tgccctcttg aatcaagcta cgcgcttgga taaagagttt tgcaatctca acaaagttct
     9481 gaccaggagt gtagagccct tctagtttcc agcgagtaaa gccatgctcc accaattctg
     9541 ttaatttgat catcaaatca aggtcattgt tggcaaagat atgggtccca tgattatctt
     9601 caaaaatgga atagtggctc tctggatcac ttggctcagc caagaagagg tcacgtttat
     9661 gcgtcttttc atcatcgata tgtgtaaagt tatagtagtt ttgcaagagt ggacgtttag
     9721 aatgatggat gacgctagca ccgtaaacca aaacttcagc aggaatttcc aaaatctctg
     9781 gcattttgaa aagttcagct gatggaattt cacgcgccaa aacagcctca gatgcgccag
     9841 ccttttgtcc ccagaagtta atctgacgac tgctagttac catggttgaa gcatcgtaga
     9901 tggtcttaaa tgaataacca tcgcggttaa ctacgtaaaa gacgcctgca tccccaatcg
     9961 taatatagtc tgtcttgatt tcttccaaga agtctaagaa aggcttgata cggtccatca
    10021 tatcttggtg catgagagca ttgaccgcaa cgatcaattc cttaccagca tcatgaacca
    10081 acttagcgat ttcacgtaat tggtcataac taaaggtcgt tggcagacga aggccaaaat
    10141 ctttctcacc gacatagata cggtctacgc cagcttcgag tagttgttca acttgttcaa
    10201 tactttcagc agttgctgta atgacaatct tttccataag aaaaattata ccacatttct
    10261 ccaaaatcag ccatgctttg aaaatgaaaa gggactttat tctttttgta acctttctgt
    10321 aataattctc tgccgaaaaa atgataaaat aggtatgtac tgttaaggag agaatcatgc
    10381 ccgtaagaaa attacagtcc tatgaggtag actatcaaga agaattaaac cagcagcttc
    10441 ctcattacca agcttataca cctgaagcgc aatctgatgc caatctcaag gaaatcctat
    10501 tttttattaa tatcgctgtt ttttgtatct gtattgctat ctttagtttt atctttttag
    10561 cattaaaatt atcaactgct cttgcctttg ccgcagcaat cggattcagc ttacttgttt
    10621 taaaagttca acggtctatt atcaaacgaa aacgtagaag ataaatccaa aatatcgccc
    10681 caattggagc gatattttta ttttttcttt ttagatggtg tctgaatggc aatcttcact
    10741 tcaaagattg ttcccttggg tttattatct ttgacagtaa cagttccttt tagagcatct
    10801 acaatttgct tggctaggga taatcctaaa ccaaaaccac ctttttgccg ggttctagct
    10861 ttgtctactc gataaaaacg gtcaaaaatt ttctttttat cttctgtcga aataccgatt
    10921 ccattatcag aaacaagtaa ataaagattg cgatcggtcg ccgagataag aaaatcaatt
    10981 tcaccatcct cctcagtata cttgacggca ttatcgaaaa gaatggtcat cagttgtttc
    11041 agaagaagct gatctgtgac aattgttcga tggatacgat tttcaaaacg gaagacacga
    11101 ttattttccg aagcaatcat ctcatagttt gtgaaagttg tattaaaaaa gctagttgga
    11161 acttctgcaa gctccggctt aatcccatca tctctccgag ctaagttcag caagcttgtc
    11221 gttaaaaaac gcatatttcg gacttcttcc aaactcgatg caatgctttc gctcacatcc
    11281 ataatggtag cttctggctt acgaaaaagg gtctctaagc gattttgcaa aactgcgagt
    11341 ggagttcgta actcatgact ggcattttcc acaaaagact gttgcttctg catactctca
    11401 agcaggggcc taacactgac cctagctaga tagagactgg caagtaaaga caaaatccag
    11461 aaactagcca tcacgaccac aatcaattgc tcatgctttt gactagcctg ctccaactga
    11521 ctggtattaa tcaagacagc agcatacttg atattggttg aaaccgaact aatattggtc
    11581 tccatcaaaa tcacacgata gatttcttcc tgcccatagc tattaaaaac ctgaatctgg
    11641 tagatatgtc ctagttcttt cttttctaac ttaatcttat ccaagcccaa aaatcgattt
    11701 ccagaaagaa gttgagtaaa gtctttatca aagagaatga cttccgtatt ggaactgaca
    11761 ttaggtttta tttctacttt actagcgtcc gccctagcat tttctaaatc tttaatctct
    11821 tctgttgccc tatttatagc cagctgaata actgcttgag gattttcact cagtccatga
    11881 agcttatcgt ccaccgaagt ataaagactc gaatgcatga cttgtaaaat aatcagagtc
    11941 attgtagaaa aaatcagggt gaagacaccg aagttgcgga taaaataact aaagtcatcc
    12001 gcataccatg tttttttaag tttactgaac atcttttaaa agatacccaa cactacgcaa
    12061 ggtttgcaaa ttctctgcaa aagtggttcc ctttaatttc ttacggactt ttgaaacata
    12121 gacttcgaca accgaaatcg ttgtatcact atcaaatccc catagacggt caaaaatctg
    12181 cgtcttaggc aaaatcacat tttgattttg aaggaaataa actagtaaat cgaactcttt
    12241 ccccagcaat tcgacaggag tatcttcaac tttaacggta ttggttgata aattaaccac
    12301 gatattccca taagtcaagg tgttttcatt aaacttccct gaacgtttga gaagggcctg
    12361 aattcgcatt ttaagttctt ctaggtagaa aggtttggtc agataatcat ccgctcccag
    12421 ttcaaatcca tgtcccttgt catccaaact ttccttggca gtcataatca gaactggtgt
    12481 cgtaattccc ttttcacgca attcttttaa gacttggaaa ccattttttt ctggcaacat
    12541 caaatccagc aaaatcaagt catagacacc actctcagct tcgtagagac cttcttctcc
    12601 atcaaatacc tgcataacat ccgcaaaatc gtctaaaaag tcaaatactg aatttgacag
    12661 acctaggtca tcctcaacca ataagatttt tatcatgaga aactcctcct tattaaaact
    12721 attataccaa atttgcctta aaaaaaactc aactctctgc attttacatg agatagctga
    12781 gtttt
//
LOCUS       DAVKBK010000048        12749 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVKBK010000048 DAVKBK010000000
VERSION     DAVKBK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.048"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..336
                     /locus_tag="VWX69_001535"
     CDS             <1..336
                     /locus_tag="VWX69_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192852.1"
                     /translation="GTTFVEANQIGAFSNFVITTSYKRTGYLTKENEGAEYIMNLNPC
                     RNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWATVGYVYAADMARQNWWDLSA
                     AISGSWSPN"
     gene            358..1149
                     /locus_tag="VWX69_001536"
     CDS             358..1149
                     /locus_tag="VWX69_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192853.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYPGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            1142..1783
                     /locus_tag="VWX69_001537"
     CDS             1142..1783
                     /locus_tag="VWX69_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192854.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLVFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            1787..2419
                     /locus_tag="VWX69_001538"
     CDS             1787..2419
                     /locus_tag="VWX69_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9192855.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            2447..2734
                     /locus_tag="VWX69_001539"
     CDS             2447..2734
                     /locus_tag="VWX69_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192856.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            2880..5393
                     /gene="secA"
                     /locus_tag="VWX69_001540"
     CDS             2880..5393
                     /gene="secA"
                     /locus_tag="VWX69_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU9192857.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            5474..6505
                     /locus_tag="VWX69_001541"
     CDS             5474..6505
                     /locus_tag="VWX69_001541"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9192858.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            6507..7538
                     /locus_tag="VWX69_001542"
     CDS             6507..7538
                     /locus_tag="VWX69_001542"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9192859.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            7577..7945
                     /locus_tag="VWX69_001543"
     CDS             7577..7945
                     /locus_tag="VWX69_001543"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU9192860.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            7935..9038
                     /locus_tag="VWX69_001544"
     CDS             7935..9038
                     /locus_tag="VWX69_001544"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU9192861.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            9057..11072
                     /gene="recG"
                     /locus_tag="VWX69_001545"
     CDS             9057..11072
                     /gene="recG"
                     /locus_tag="VWX69_001545"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU9192862.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLI
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            11389..12369
                     /locus_tag="VWX69_001546"
     CDS             11389..12369
                     /locus_tag="VWX69_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU9192863.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT         3701 a         2389 c         2901 g         3758 t
ORIGIN      
        1 ggaactactt tcgtagaagc aaatcagata ggtgctttta gtaattttgt tattactacc
       61 agttataaga gaacaggtta tttgactaaa gaaaatgaag gtgcggaata tatcatgaac
      121 ttaaatcctt gtagaaattt acatcccatg actgttaagc atcgtatagt aaattctaat
      181 ggagaagctc gtagtggaga atcgttaaca acctgtggta ctcgttcaac tcatggtaat
      241 tgggcaacgg ttggctatgt ttatgcagca gatatggcaa gacaaaattg gtgggattta
      301 tcagctgcca tttcaggtag ttggtcacca aattaattcg taaagtaggt ataatttatg
      361 aagattcctc tcttaacttt ggcaaggcat aaatttgttt atgtcttgct tactttgctt
      421 tttcttgctt tggtttatcg tgacgttttg atgacttatt tcttttttga tattcatgcg
      481 cccgatctag ctaaattcga tggacaagca attaaaaatg acttattaaa atcagcatta
      541 gattttcgta ttctccagtt caatctaggt ttttatcaat catttattat tccaatcatc
      601 attgttttgc taggttttca atatattgag ctgaaaaata aagttttacg attgagtatt
      661 ggaagagaag tgagctatcc agggttaaaa agaaagttga ctttgcaagt tgcaagtatc
      721 ccttgtttga tatatttagt gactgtgctg acaattgcaa ttataaccta tttccttggg
      781 actttttctc ctcttggatg gaattctcta ttttctgatg gaagtggttt acaaagactc
      841 ctagatggag agataaaaag ctatttgttc tttacttgtg tcctgctaat cggtattttc
      901 atcaatgcaa tctatttttt acaaatagtt gattatgtgg ggaatgtgac tcgttcggca
      961 atcacctatt tgatgtttct ttggcttggt tctatgctgc tctatagtgc cttgccttac
     1021 tatatggttc ctatgacgag tttgatgcaa gctagctatg gggatgtaag tttgatgaaa
     1081 ctctttactc cttatatcct ttatattgtc ccttacatgg tgcttgaaaa atatgaagat
     1141 aatgtttaag aattttaaca atattttgct aaagagaaag attgttttac tacttcgtat
     1201 agttctgatg atgattttga taaaccatct attgtcaaca gcggttcaaa agcaggatgc
     1261 tgttatcttt ttcaagagag aattgatttc aattttttcc tataatgact attctgaagc
     1321 gaatttagaa atccccaaac tcttgttaaa cctttcgctt ttcatggtag gatggctctc
     1381 tgtcatttta cttgaaagtg atttggcaga ccattaccat cacttgattc gctatcaatc
     1441 aagctccttt ttcgattata caaggaaacg attggttgtc atttctaaat tttttactca
     1501 agatttgttt gtctggttcc ttggtttact tccgctagga attcatttca aaacagtcgc
     1561 acttttcttt ttacttgctc agttaatgat gttgtactta ctactgtctt atctgatagc
     1621 actgattagt gcgggcgctg gtttttcctt ttttctctat tttttagtat ttgtgggaca
     1681 agaatggatg atggatcata ttgtaacagt gtatttacta ctcttaagtt tattagttat
     1741 gttgattgtt agtcgcttgg aagagaaatt taagaaagga taaacgatga gacttgaaat
     1801 tataaatgga cagaaaattt atgggaaaag acctatttta aatcagttga atttggtgtt
     1861 tcaatcagga aaaatttatg gacttaaagg tgataatgga tctggcaaga cggttctttt
     1921 aaaggtactt gctggctata ttaagcttga caaaggaaaa gttcttcaag acgggaaagt
     1981 ctacgggata aaaaatcatt atattcagga tgcaggaatt ttaattgaaa aagtcgagtt
     2041 tttatctcat ttatccctga gagaaaattt ggaactgtta aggtattttt catctaaagt
     2101 tacggaaaaa agaattgcct attggattca atactatgat ttacaggaat ttgaagacgt
     2161 tgaataccgt catttatcct tgggaacaaa gcaaaaaatg gccttgattc aagcctttat
     2221 ttcctctcct tctatactct ttctcgatga acctatgaat gctttggatg agaagagtgt
     2281 gaggttaacc aaacaggtca ttttatctta cctgaaaaaa gaaaatggtc tggttatcct
     2341 gacgtcgcac atatcggaag atatttcaga cctttgtaca gatgtattag ttgtcgaaaa
     2401 tggacatata caaatgtaaa ggatatacaa tcctaggaga tggcttatgg cacatctaaa
     2461 atcatttatt acacgctatt ccaaggttta tattggttta gttctgctga tctggctgtc
     2521 tttcttcttt atcccttggg atagagcgat tctgggggta aggattgaca tcttcatcat
     2581 acagaaaatc ttgctagctt ttggaattct gtccattctc atggccttgc tgtccaagaa
     2641 agtcagtctc tttgtttttg gactgatttg ctgtctttct ctttggatta acttatttat
     2701 cacatttgcc attttgccga tttttggcaa ttaaacagtc ataaaagtcg gagaggttag
     2761 cttgaaaact aacctctttt tccttttcaa aatggggatt cttccttgaa aataatcagt
     2821 aattgtgcta aaattaaagg aacattctaa aatattcgga atttaaagta aggaaaaaca
     2881 tggctaatat tttaaaaaca attatcgaaa atgataaagg agaaatccgt cgtctggaaa
     2941 agatggctga caaggttttc aaatacgaag accaaatggc tgctttgact gacgaccaac
     3001 taaaagcaaa aacagttgaa tttaaggaac gttatcaaaa tggagaatca ctggattcat
     3061 tgctttacga agcatttgcg gttgtccgtg aaggtgccaa acgtgtccta ggtctcttcc
     3121 cttataaggt tcaggtcatg ggggggattg ttcttcacca tggtgacgtg ccagagatgc
     3181 gtacagggga agggaaaacc ttaactgcga ccatgccggt atacctcaat gccctttcag
     3241 gtaaaggggt tcacgtagtt acggttaatg aatacctgtc agaacgtgac gcgactgaga
     3301 tgggtgaatt gtactcttgg cttggtttgt cagtagggat taacttggct accaaatctc
     3361 caatggagaa aaaagaagcc tatgagtgtg atattactta ctcaactaac tcagaaatcg
     3421 gatttgacta ccttcgtgac aacatggtcg ttcgcgctga aaacatggta caacgtccgc
     3481 ttaactatgc cttggtcgat gaggttgact ctatcttgat tgacgaggct cgtacacctt
     3541 tgattgtatc aggtgccaat gcggttgaaa ccagtcagtt gtatcacatg gcagaccact
     3601 atgtaaaatc tttgaacaaa gatgactaca tcatcgatgt gcagtctaag actattggtt
     3661 tgtctgattc agggattgac agggctgaaa gctacttcaa acttgaaaac ctctatgaca
     3721 tcgaaaacgt ggctttgacc cactttatcg ataacgccct tcgtgccaac tacatcatgc
     3781 ttctcgatat tgactatgtg gtgagcgaag agcaagaaat cttgattgtc gaccaattta
     3841 caggtcgtac catggaaggt cgtcgttatt ctgatggatt gcaccaagct attgaagcca
     3901 aagaaggtgt gccaatccag gatgaaacca agacatctgc ctcaatcacg taccaaaacc
     3961 ttttccgtat gtacaaaaaa ttgtctggta tgacgggtac aggtaagact gaggaagaag
     4021 aatttcgtga aatctacaac attcgtgtta ttccaatccc aacaaaccgt cctgttcaac
     4081 gtattgacca ctcagacctt ctttatgcaa gtatcgaatc taagtttaaa gcggttgtcg
     4141 aagacgttaa ggctcgttac caaaagggtc aacctgtctt ggttggtaca gtagcggttg
     4201 aaactagtga ctacatttct aagaaattgg ttgcagctgg tgttcctcac gaagtcttga
     4261 atgccaaaaa ccactataga gaagcccaaa tcatcatgaa tgctggtcaa cgtggtgccg
     4321 ttaccatcgc aaccaacatg gcgggtcgtg gtaccgacat caagcttggt gaaggtgttc
     4381 gtgaacttgg aggactttgt gttattggta cagaacgtca tgaaagtcgt cgtatcgata
     4441 accagcttcg tggacgttca ggtcgtcaag gagatccagg tgagtcacaa ttctacctat
     4501 ctcttgaaga tgatttgatg aaacgttttg gttctgaacg cttgaaggga atctttgaac
     4561 gtctcaacat gtctgaagag gccattgagt ctcgcatgtt gacgcgtcag gttgaagcag
     4621 ctcagaaacg tgtcgaagga aataactacg atacccgtaa acaagtcctt caatacgatg
     4681 atgtcatgcg tgaacaacgt gagattatct atgctcaacg ttacgatgtc atcactgcag
     4741 atcgtgactt ggcacctgaa attcagtcta tgatcaaacg cacgattgaa cgtgtcgttg
     4801 atggtcatgc gcgtgccaaa caagatgaaa aactagaggc aattttgaac tttgctaagt
     4861 acaacttgct tcctgaagat tctattacga tggaagactt gtcaggcttg tctgataagg
     4921 ccatcaagga agagcttttc caacgttcct tgaaggttta cgatagtcag gtttcaaaac
     4981 tacgcgatga agaagcagtt aaagaattcc aaaaagtttt gattctacga gtggtggata
     5041 acaagtggac agatcatatc gatgcccttg atcaattgcg taacgcggtt ggacttcgtg
     5101 gctatgctca gaacaaccct gttgttgagt atcaggcaga aggtttccgt atgtttaatg
     5161 atatgattgg ttcgattgag tttgatgtga cacgcttgat gatgaaagca caaattcatg
     5221 aacaagaaag accacaggca gaacgtcata tcagtacaac agcgactcgc aatatcgctg
     5281 ctcaccaagc aagtatgcca gaagatttgg atttgagcca gattggacgc aatgaacttt
     5341 gcccatgtgg ttctggtaag aaatttaaaa actgtcacgg taaaagacaa taaaatgaga
     5401 tagtttagag gcggatatct tgtgaaaagt aaatttttac tgggtatccg tttgctttat
     5461 aaggagatga gttatggtat ttacagcaaa aagctctaaa ataaatatag aagaagttcg
     5521 tgccttgtca aaattagaag gtcaggcttt ggagaggaaa tcacagcgag atcaagagct
     5581 agaagccatt atacgtggag aagaccagcg aattctcttg gtaatcgggc catgctcatc
     5641 tgacaacgaa gaagctgtcc ttgaatacgc taagcgtttg gcagtcctac aagaagaagt
     5701 ggcagatcgt atctttatgg ttatgcgtgt ttatactgcc aaaccccgta ccaacggaga
     5761 tggctataag ggcttgattc accagcctaa cgcgacagaa gcgcctagtc ttatcaatgg
     5821 aatcaaagcc gttcgccatc ttcactatcg tgtcatcaca gaaacaggga tgacaactgc
     5881 tgatgaaatg ctttatcctg aaaaccttcc gcttgtagat gatttgattt cttacatggc
     5941 agttggtgcc cgttcagttg aagaccagca acaccgcttt gtggcaagtg gggcaggatt
     6001 ttctactggt tttaaaaatc caacctctgg aaatctcaat gtcatgttta atgggattta
     6061 tgctgctcaa aacaaacaaa gtttcctttt cttaggaaaa gaagtagaaa caactgggaa
     6121 cccgctttca cacgctattc ttcgtggtgc tcttaatgag tatggaaaaa atattcccaa
     6181 ctactattat gacaatttaa ttgataccat tgcccagtat gagaaaatgg gcttggaaaa
     6241 tccttttatc atcattgata ccaatcatga caattctggt aagcagtata ttgaacagat
     6301 ccgaattgtc cgccagacct tgattaaccg tgcttggaat gaaaaaatta agcagttcgt
     6361 tcgtggtttt atgattgagt cttatctgga agatggtcga caaaatgagc cagaagtatt
     6421 tggtaagtct atcacagacc cttgcctggg ttgggataac acagaagctc ttgtcagaga
     6481 aatttacaaa acgttaggag aataagatgg catttattga aaaaggtcaa gaaatcgata
     6541 tggaagtcat caaggctgaa acccaattgt ctgcggaagc cttgagactc aaggaaagcc
     6601 gtgacaggga attggcagat attatttcag gggaagatga ccgtattctc ttggtgattg
     6661 gtccttgctc ttctgataat gaagaggcgg tcttggaata tgctcgccgt ttatctgcct
     6721 tgcaaaagaa ggtagcggat aagattttca tggtcatgcg cgtgtatact gctaagcctc
     6781 gtaccaatgg agacggctat aaaggattag ttcaccagcc agatacttct aaggctccaa
     6841 gcctgattaa tggcttgcag gctgtgcgcc agttgcacta ccgcgtgatt acagagactg
     6901 gtttgacaac ggcagatgag atgctttatc cgtcaaatct gatcttggtg gatgacttgg
     6961 tcagctacca tgccgttgga gctcgttctg tggaagacca agagcaccgc tttgtggctt
     7021 ctgggattga tgcaccagta gggatgaaaa atccaacctc aggaaatttg ggtgttatgt
     7081 ttaacgccat ctatgctgct caaaacaagc aaaccttcct ttatcatggg caggaagttg
     7141 agacatcagg taatcctttg gcccatgtta tcctccgtgg agcagtcaac gagtatggca
     7201 attatatgcc gaattactac tatgaaaatc tactccaagc cattgaacgc tatgaaacca
     7261 tgggacttga aaatcctttt atcctcattg acaccaacca tgataactca ggcaagcaat
     7321 atatggagca gattcgaatt gttcgccaga ccttgcagaa tcgtgattgg aatgagaaaa
     7381 ttaaaaagac ggttcgagga tttatgattg aatcttacct agcagatggt cgtcaaaacc
     7441 aaccagagat ctttggttgc tctattactg acccttgcct aggttgggaa aatacagagg
     7501 ccttggtaga agagatttat gttaccttga caaaataagt gaaaaggatg gagttgggga
     7561 atctcaactc cttttgatga gaatgatagt tggacacgga attgacatcg aagaattggc
     7621 ttcgatagaa agcgcagtta cacgacatga aggatttgct aagcgtgtac tgaccgctca
     7681 ggaaatggag cgcttcacca gtctcaaagg acgcaggcaa atagaatatt tagctggtcg
     7741 ctggtcggct aaggaggcct tttccaaggc tatgggaacg ggcattagca agctcggttt
     7801 tcaggatttg gaagtcttga acaatgaacg tggggcgcct tattttagtc aggcaccatt
     7861 ttcaggaaag atttggctgt ctatcagcca caccgatcag tttgtgacag ccagtgtcat
     7921 tttggaggaa aatcatgaaa gctagtccac atagaccaac caaggctctg attcatctgg
     7981 gagctattcg acaaaatatt cagcaaatgg gggctcatat ccctcaagga acgctcaagt
     8041 tggctgtggt taaggccaat gcttatggtc atggagctgt tgccgttgcc aaggcaattc
     8101 aagatgatgt tgatggcttt tgcgtttcca atatcgatga agccattgaa ctcagacaag
     8161 ctggactcag caagccaatc ctcattttag gagtttctga aatcgaagct gttgctctag
     8221 ctaaagaata tgacttcacc ttgacagtgg ctggactgga gtggattcaa gcactcttag
     8281 ataaggaagt ggacctaact ggattgacag tccacctcaa gattgattca gggatgggac
     8341 ggattggttt tagagaggca agtgaggttg agcaggctca agatttgctc caacaacacg
     8401 gtgtttgtgt tgaaggaatc tttacccact ttgctactgc tgatgaggaa tcagatgact
     8461 attttaatgc ccagttagaa cggtttaaaa ctattttagc tagtatgaag gaagttccag
     8521 agctggttca tgctagcaat tctgcaacga ctctttggca tgtagagact attttcaatg
     8581 cggttcgtat gggagatgcc atgtatggcc tcaatccaag tggagcggtc ttggatttgc
     8641 cttatgattt gataccggcc ttgaccttgg agtctgctct ggttcatgtc aagacagttc
     8701 cagctggagc ttgcatgggc tatggagcaa cttatcaagc ggatagcgag caagtcatcg
     8761 cgaccgtgcc aatcgggtat gcagatggat ggacaagaga catgcaaaat ttctctgtct
     8821 tggtagatgg ccaagcttgc ccaattgtcg gcagggtttc gatggaccaa atcactattc
     8881 gattgcctaa gctttatccg ctaggaacca aggtaacctt gattggctcc aatggggata
     8941 aggaaatcac tgcaactcag gtagcgacct accgcgtaac cattaactat gaggtggttt
     9001 gcctcctcag cgaccgtatt ccgagagaat attattagaa aagaaaggag tggagcatga
     9061 atctacatca acccttgcat gtcttgcctg gtgtgggacc aaagtcagca gaaaaatacg
     9121 ccaaactagg aattgaaaac ttgcaagatc tcttgctcta ctttcctttc cgttatgaag
     9181 acttcaaaac caagcaggtg ctggagctgg aagacggtga gaaggcagtt ctttctggtc
     9241 aggtagtgac tcctgctagt gtccagtatt atggtttcaa gcgcaatcgc ctgcgtttta
     9301 gtctcaagca gggagaggtc gtttttgcgg tgaatttctt taaccagccc tatctggctg
     9361 ataaaataga gttgggagca acccttgctg tctttggaaa atgggaccgc gctaaggcta
     9421 gtctgactgg gatgaaggtt ctggctcagg tagaagatga cctccagcct gtctatcgtc
     9481 tggctcaggg aatcagtcag gccagtctgg tcaaggtcat caagacggct tttgatcagg
     9541 gactggacct cttgatagaa gaaaatctgc cccagtcttt actagacaaa tacaaactca
     9601 tgtcccgttg tcaggcagtc cgagctatgc attttccaaa ggatttggca gaatacaagc
     9661 aggctcttcg ccgtataaag tttgaggaac tcttttattt ccaaatgcag ctgcagatgc
     9721 tcaagtctga aaatagagtt cagggaagtg gtctggttct gaattggtct caggaaaaag
     9781 tgacagcagt taaagtaagt cttccttttg ccctgaccca agctcaggaa aagagtttgc
     9841 aggaaatttt aactgatatg aagtccgacc accacatgaa tcgtctccta caaggggatg
     9901 tggggagtgg aaaaacggta gtcgctggct tggccatgtt tgcggcagtg acagcaggtt
     9961 atcaggctgc cctaatggta ccaacagaaa tcctcgcaga gcaacacttt gagagtttac
    10021 agaacctttt tcccaatttg aaactggctc tcttgatagg ttccttgaaa gctgcagaaa
    10081 agagagaggt cttggagacc attgccaagg gtgaggctga tttgattatc ggaactcacg
    10141 ctctgataca agatggggtg gagtatgctc gtcttgcttt gattattatc gatgagcagc
    10201 accgttttgg tgtagggcaa aggcgtattt tacgggaaaa aggtgacaat ccagatgtcc
    10261 tcatgatgac ggcgactccc attccacgga cgcttgccat cacagccttt ggagatatgg
    10321 atgtttccat tatcgaccag atgccagcag gtcggaagcc tattgtgacg cgctggatca
    10381 aacatgagca actacctcag gtcttgactt ggttagaggg ggaaattcaa aaaggttccc
    10441 aagcctatgt catctctcct ttgattgaag aatcagaagc tctagatttg aaaaatgcca
    10501 ttgccttatc agaggagttg acgactcatt ttgcaggcaa ggcagaggtg gctcttctac
    10561 atggtaggat gaagagtgac gaaaaagacc agatcatgca ggatttcaag gagagaaaga
    10621 cggatattct ggtttcgacg acggttattg aggttggggt caacgttccc aatgcgactg
    10681 tcatgattat catggatgcc gatcgcttcg gtctcagtca acttcaccag cttagaggtc
    10741 gtgtcggtcg gggggacaag cagtcctacg ctgttctcgt tgctaatccc aagacggatt
    10801 ctgggaaaga ccgcatgcgt atcatgacag aaacgaccaa tggatttgtc cttgcggagg
    10861 aagatttgaa aatgcgtggt tctggtgaga tttttggaac cagacagtca ggacttccag
    10921 agttccaagt ggctgatatt atcgaagatt ttccgatttt agaagaagca agaaaggttg
    10981 ctagctacat tagttctata gaagcttggc aagaagatcc agagtggcgc atgattgccc
    11041 ttcatctgga aaagaaagaa catctggatt aagctttctc taaggaaaac ttaagctagt
    11101 ttttaggttt ggctcttata ctaaagtcat caaaaagaaa cgaggactct catatgacag
    11161 taacgattaa agtaaattac caaaccactt tccaaaagaa ggaagcaaaa aactagtata
    11221 aacagaagag agagcgaaat gctctttttt cgtttctaaa actactttca gcccatcatc
    11281 ctaaaagtaa agaatctaaa ttcactttct atttaccctt ctttcttgca ttgattacat
    11341 agatatgcta cagttgtggt aacgattaca aaataaaagg agcatgctat gaaaaatcca
    11401 gctttgctag aagaaattaa gacctataga ggaagggatg aggttccgga agactttgat
    11461 gctttctggg atggggaagt gaaaaatgtt tccacacttc catcctacca cttggaggaa
    11521 agagatttcc acattcctca agtcaagtgc tatgagttaa catttgaagg aagcaaggaa
    11581 ggaaaggtct atgcacgcat tgttcttcca aagagtgagg agaaggttcc attaatcttc
    11641 cattttcatg gttatatggg acgtggctgg gactgggccg acatgctggg cttcaccgta
    11701 gctggttacg gtgttgtttc catggatgtg cggggccagt caggttactc acaagacggc
    11761 ttgcgttctc ctttaggaaa taccgtgaag gggcatatta tccgtggtgc tatggaaggt
    11821 cgggaccacc tcttttataa ggatgtttat ctggatattt accagttggt cgaaattgtt
    11881 gctagtctgt ctcaggttga tgagaagcgt ctttctagct atggtgcctc acaaggaggg
    11941 gctctagctc tagttgcagc agcgctcaat cctcgaattc agaaaacagt tgccatttat
    12001 cccttcttgt cagacttcag acgggtgatt gagattggta atactagcga ggcttacgac
    12061 gaacttttcc gttatttcaa gtttcacgac cccttccatg aaacagagga ggaaatcatg
    12121 gcgacccttg cctatatcga tgtcaaaaat cttgcccatc gtatccaagg tgaggttaag
    12181 atgattacgg gcttggacga cgatgtttgc tatcccatta cccagtttgc gatttataat
    12241 cgtctgacct gcgataaaac ctatcgcatc atgcctgagt atgctcacga agccatgaat
    12301 gtatttgtca atgaccaagt ctacaactgg ctctgtggaa gtgagattcc ttttaaatat
    12361 ctaaaataag gagtcgactc taagcacaaa atcttaaaaa ttacaaacac gcatagtatc
    12421 aggggattaa aaaaacttga tactatgcgt tttatcatgg aaatatagta aaatgaaaca
    12481 agaataggac aaaacgatca ggacagtcaa atcgatttct aacaatgttt tagaagcaaa
    12541 tgtgtactat tctagtttca atctattata tttatagaat tttttgttgc tagatttgtc
    12601 aaattgctta aaataatttt tttcagaaag caaaagccga tacctatcga gtagggtagt
    12661 tcttgctatc gtcaggcttg tctgtaggtg ttaatacttt tcaaaaatct ctttaaacca
    12721 cgtcagcttc gccttgccgt atatatgtt
//
LOCUS       DAVKBK010000049        12500 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVKBK010000049 DAVKBK010000000
VERSION     DAVKBK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.049"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(359..784)
                     /locus_tag="VWX69_001547"
     CDS             complement(359..784)
                     /locus_tag="VWX69_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192864.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(928..1296)
                     /locus_tag="VWX69_001548"
     CDS             complement(928..1296)
                     /locus_tag="VWX69_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192865.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKK"
     gene            complement(1318..1524)
                     /locus_tag="VWX69_001549"
     CDS             complement(1318..1524)
                     /locus_tag="VWX69_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192866.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(1511..1672)
                     /locus_tag="VWX69_001550"
     CDS             complement(1511..1672)
                     /locus_tag="VWX69_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9192867.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(2031..2987)
                     /gene="lytA"
                     /locus_tag="VWX69_001551"
     CDS             complement(2031..2987)
                     /gene="lytA"
                     /locus_tag="VWX69_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU9192868.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(3363..4733)
                     /locus_tag="VWX69_001552"
     CDS             complement(3363..4733)
                     /locus_tag="VWX69_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9192869.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(5040..6206)
                     /gene="recA"
                     /locus_tag="VWX69_001553"
     CDS             complement(5040..6206)
                     /gene="recA"
                     /locus_tag="VWX69_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU9192870.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(6261..7517)
                     /locus_tag="VWX69_001554"
     CDS             complement(6261..7517)
                     /locus_tag="VWX69_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU9192871.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(7602..8618)
                     /locus_tag="VWX69_001555"
     CDS             complement(7602..8618)
                     /locus_tag="VWX69_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU9192872.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(8626..9144)
                     /locus_tag="VWX69_001556"
     CDS             complement(8626..9144)
                     /locus_tag="VWX69_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9192873.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGELFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(9134..9577)
                     /gene="tsaE"
                     /locus_tag="VWX69_001557"
     CDS             complement(9134..9577)
                     /gene="tsaE"
                     /locus_tag="VWX69_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU9192874.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(9663..10283)
                     /locus_tag="VWX69_001558"
     CDS             complement(9663..10283)
                     /locus_tag="VWX69_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192875.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTVFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(10666..11529)
                     /locus_tag="VWX69_001559"
     CDS             complement(10666..11529)
                     /locus_tag="VWX69_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9192876.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            11994..12218
                     /gene="pneA1"
                     /locus_tag="VWX69_001560"
     CDS             11994..12218
                     /gene="pneA1"
                     /locus_tag="VWX69_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEU9192877.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            12225..12413
                     /gene="pneA2"
                     /locus_tag="VWX69_001561"
     CDS             12225..12413
                     /gene="pneA2"
                     /locus_tag="VWX69_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEU9192878.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
BASE COUNT         3859 a         2661 c         2040 g         3940 t
ORIGIN      
        1 taaaatataa gttttttgat aaaataacca aaaactactc cctatcccct ctcacattac
       61 cctacatatc gtttgacatg cgactgatag ttcaggaaaa cttcaaggag aacttttctc
      121 tcatccacta tgcaggactt actatttcac ttctactcct ataggctcaa tttgacactt
      181 ttctttttcg aattgctcat atgcctcctg aatagtgagt tcgatttatc caaatttatt
      241 tttgtctatt ttgatgaata cttccacgaa gatagtctga aaatgaattt gcaccaattt
      301 tccttctctt tttaagcata ttattccaga tatgattgcc ctcttgttca gtaataaatt
      361 acgctttaaa cgcttcaatc agtatatctc ctgttgtcat atgttctaaa gaaaattctt
      421 ctacatatga tttaacatct cttaggttat tacttcctaa tatcccatta tgctttttcg
      481 ctaaggaaat agaagccgct tctcccttac caataatctt gttactatca tgatttcttg
      541 ttaaatctct atataatgcg tattcttcag ttccaatgtc tatgctcaca atctcagctg
      601 aacccttagc taccaactga tctatcctag attttaaatg gggaattgta ggtatattga
      661 tttcatcata cacctcttgt ggaataacaa ttttacccga atagagcttt tctaaaagat
      721 gttcagtacc aacccataaa aatactgaaa tacaatctgc atcaataaat acacgactag
      781 tcaaacgaca actcccccct cttcatctag cccatataca atatcatatc tgaaagcatc
      841 tagtaacagt tcctcatact tcccttgcga aattctgtta ttttctaaaa gttgttcagt
      901 tgaattaaca tattatccta atatcattta ctttttactt tctgacaaag gacgatataa
      961 acttgtatca tagcctaatc ttgaagctgt ctctataaca ctaatatcca tatttttaat
     1021 ttcttctgca tcaaggtatc catcattcct caatctatat aacataactt tatgactgat
     1081 accataaaac tgacccaatt ttataatatc ttctacttca agatgagttc tattggcatt
     1141 ttctctaatt tcctcaacca tcctatacag tgaagatggg aaaattaaaa aataagaagc
     1201 aaactgatcc gcttttcttt cagtttcatc tccttcacca atcaagataa gactgactga
     1261 actcttcttc acctcatcat aataaagatg atacagttca tgtgctaaag aaaatcttta
     1321 ccttcctaat gacatgtctg aattgactgc aatgagactg aactgagttc ctttataaca
     1381 gactccgcta atattctttc cgagtccata aaataccagc gtcaaatttt ctatcttttg
     1441 taccaattta aaaatatcta tcggcgattc accatcagct cccaactttt ttctaagatt
     1501 tgaagcttta ttacttaaat ccattcgtga tattcctttc acctttttcc attttggcaa
     1561 tcatgctttg attcaaagac aaatactcag caatcttatc ttgagtaaga tttgaagata
     1621 ttctaagttc ttttattctt tttccaacat cacatacatt tatcacatac atttatcata
     1681 ttcatacacc tctcataaaa agaatagcac acttttgtca taatttttta aataaaaaaa
     1741 ttatgacaaa acaaggaagc aatttattga tgctgcttaa aaatctaaaa ttgatgagtt
     1801 cctatcaaaa atcgtatctt caacctcaaa acagtactta aagctatccg actcggttta
     1861 cattgtcaaa tttagatttt atttgagcat aactttctag tttgctttct gatttttgtt
     1921 taatatagta gcaaacattg aaggaaatat ctccacaaaa aaacgcatac tattaagctt
     1981 tttcaagacc taataatatg cgctgttctg atttgaaaga cattccatta ttattttact
     2041 gtaatcaagc catctggctc tactgtgaat tctggcttgt ctgccagtgt tccgtctggt
     2101 ttgaggtagt accagcctgt tccgtccgct gactggataa aggcatttga taccatggcg
     2161 ccttctttag cgtctaagta gtaccaagtg tccttgtact tgacccagcc tgtcttcatg
     2221 gcaccttctt cgttgaaata gtaccactta tcagcgattt tcttccagcc tgtagccatt
     2281 tcgcctgagt tgtcgaacca gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca
     2341 agcatatagc ctgaactgtc aaagtagtac caagtgccat tgattttctc aaacttgtct
     2401 tttggataag agccgtctga atgtacgtac cagtagccag tgtcattctt ctgccagcct
     2461 gtttcaatcg tcaagccgtt ctcaatatca tacttaaact gctcacggct aatgccccat
     2521 tttgccaagt aagggtatgg atccacatgg tctgagtggt tgtttggttg gttattcgtg
     2581 caatactcgt gcgttttaat tccagctaaa ctccctgtat caagcgtttt cggcaaacct
     2641 gcttcatctg ctagattgcg taagagttcg atataaaggc ggtagtccgt catgaactct
     2701 tctttagttg aatggctttc aatcagttca accgctgcat aggtttcagc attccaaccg
     2761 cccccaacgt cccaggcacc attatcaaca ggtcctacct gcatgatgca accgttccca
     2821 acaatgtgcg agaaaaaacc taattctggg tctttccgcc agtgataatc cgcttcattc
     2881 tgtacggttg aatgcggatt cccagttgag tgtgcgtgta cttgcctata tggttgcacg
     2941 ccgacttgag gcaaatctgt tcttaattta ctcacattaa tttccatatt ctactcctta
     3001 tcaattaaaa caactcattt tttacaatcc agaaccagaa actcctttat ttctacctta
     3061 caaagaagac aatcttagtc acgattaggc ttgtagatag aacctcaaaa cgcactattt
     3121 tgacactgta aataggactg acaaggtctg cattctatct acaataacac cccagactaa
     3181 aaagcttttc aaaagtatat ttttacagtc tctatatgtc cttttcataa atactatact
     3241 ttattatatc atataaaaga agtcaaaagt ctgttaaact attttcaaca ccaaactaaa
     3301 gaagagaaca caagtttttt cgatgttcac tagaggaaat ggattttatt cagtaaatcc
     3361 aactaggatt gcactttggt tgccaaaatt gcctttcctt cttttatcaa gggatgacgg
     3421 aatagtgaga agtacagttg aactgtcatg gcaacccaga taagaggttc acaaaggata
     3481 acacccttat atcctgccca aggaataatc aaaaccacaa aaacgatttt tccgattagt
     3541 tcaataaagc tagaaactag aggaaggatc ttctgcccca agccctgcaa gcaattgcga
     3601 taaatcaaca agaggctcaa aatgggataa aaggctgaac tgatttgcag atagagactt
     3661 ccattttcta tcaagtaacc atctgtcgaa ctagccaaga aggaaaccaa ggctggactg
     3721 gcaaaaaaga ggaaaataca aacaaaaact gcccaggata tacttaaacg actgccgatt
     3781 cgaagacctt gaacaatgcg gtcaggtcgc ttagctccta gattctgaga agcaaaggtc
     3841 gtcattgatg cagaaatagc ggtcatagga agaagggcaa aggtcataat gcgtcgagct
     3901 gccgtctggg cactaataat cactgcacca aatgtattaa cagaaaactg taaaatcaca
     3961 ctgccgatag atacaattga actcatcaag cccatagcca aaccttgctc caagagatcc
     4021 gcgtacaagc ttttgtccca tttgaaatgt ttaaactgtg gcaagagttc tggcacactt
     4081 ttacgaatat aataaaagca gagaaccgct gataaacctt gcgaaataat ggtagcaagt
     4141 cctgcggatt gaactcccag atgcaattgc gtaataaaat agagatccag aaccacatta
     4201 accaaggcag agaaaatcag aaatcccagg gctgctagac tgtcaccaat agaccgcaac
     4261 aagcctgcaa aaagattata agcaaagctg acacctacac aggtcacaat catagaaata
     4321 tattgataag attgaggaag aatttctgca ggagtatcta agtattgcaa gagaggatac
     4381 aagccaagaa agcccagcaa cataactaga atgctcaaaa gagcacctaa aatccaggtg
     4441 gctgctactg cttccttgat tttagtgaaa ttccgagccc cataataacg agcaatgaca
     4501 atccccatgc cattgccaac accaagtgta aagcctacaa tcaggtcaaa aatcgctgtc
     4561 gtcgctccta ctgcagccaa ggattcttga ccaagaaatc gtccaacaat caagacatca
     4621 gcagtgttat agagctgttg aaaaatattt gatagcaaga ttggaaaggt gaagcttaag
     4681 agcgagggaa gaatcggacc atgtatcagg tccactgttc gttttttatt cataaagcta
     4741 ttatatcagc tttccagagg agcgacaaga aacagcaaac ttatatatag cggaatgaaa
     4801 taaggacagt caaatcgatt tttaacaatg ttttagaagt agatgtgtac tattctagtt
     4861 tcgatctatt atagttggtt gagtttggaa tagtacgctg tagctgctaa aacatttcta
     4921 gaaattaatt tgactttcct aataaagttg ttcatatctt atttcaagct actatatata
     4981 atctaaaaac ttgaatcaaa aatcgaaaaa gtagcggatt tctccactgc tttaacagct
     5041 tattcttcaa tttcgatttc aagttcatcg cctaagtcaa gcggaacttc ttcattcact
     5101 gcttcttctt tctttggctc atcttttttg ttttcagtat cttgttctga aacttcttct
     5161 ccatcaatca agccaaattt agaacggact tgcttatcaa tttcatcaaa gatttctggg
     5221 tgctctgcca agtatttctt agcattctca gaaccttgcc caattttttc atctttgtaa
     5281 gaataccaag cccctgcttt tttgataata tccaaatcgc ttgcaatctt caaaagctca
     5341 ccagtcttag aaattccttc tccgtacata atttcaacta cggcttcctt aaacggtgga
     5401 gctaccttat tttttacaac cttaatctta gtttctttac cgacattggt ttctttttga
     5461 tcaccagttc ccttaatttg tgtattacca cgaacatcca agcggactga agcatagaat
     5521 ttcaaagcac gtccgcccgg tgttgtttct ggatttccaa acatcactcc aactttttca
     5581 cgcaattggt tgataaaaat ggcaattgtt ttggttttat tgatagaggc gccaagttta
     5641 cgcatggcct ggctcatcat acgagcctgc aaaccaacat ggctatctcc gatatctcca
     5701 tcaatttccg cacgaggaac aagggcagca actgagtcga ctacgacaag atcaactgca
     5761 cctgagtcaa tcaattttcc cgcaatctca agaccttgct ctcctgagtc tggttgagac
     5821 aagagcaatt cgtcaatatt gacaccaagg gccgcagcat aagctggatc aagggcatgt
     5881 tccgcatcga taaaggcagc aatcccacct tctttttgcg cttgtgcaac tgcatgaagg
     5941 gcaaccgttg tcttaccaga tgactctggg ccatagattt cgatgatacg tcccttagga
     6001 taaccacctg agccaagggc aatgtcaaga gctaaagaac ctgagctcat cacttgcacc
     6061 ttttgctccg cacgttcacc caaacgcatg attgatcctt taccaaagtc tttctcaatc
     6121 aatttaagag catcattcaa ggccttttca cgttctgccc caaatttttt tgaaatttct
     6181 tctaattttt ttggtttttt cgccattcta ttctcctaca ttctaatgat cctcagacct
     6241 atctactatt atatcaaaag ttagtcactt aataaagcct tgcgaactag gttaaaggca
     6301 tgcataaccg caatatgacg tacatctgct cggcttctgc ctccaatatt aaccttgata
     6361 acctcagttc cttgctcttg cgccaagcct atgaagactg tcccaactgg gtgtccttct
     6421 aggctatctg gtcctgccac tccggtcaaa ctaattccaa aatcagactg ggtcttgctt
     6481 cgtgcctgct cagccatctt ctgagctgta aattcagaca ccacaccatg ttcttccaaa
     6541 ttcttggcag gaatatccaa catccttgat ttttcctcca agctataggt cacaaaacca
     6601 cccttaaata tacttgaagc tccagaaaaa ttcgccacgg tagcttggaa aagacctgcc
     6661 gttaaactct ctgcagccgc gatggttttc ccttgccttt tcagttcttc taccacaatg
     6721 ctggctaaac tagtttcttc cccataacca tagcaaaagt ctcgtaaaga aattccttcg
     6781 aaagtctggc agtccaagat ttgattttcc aagatatcca gcgcttgatt cgcctcttct
     6841 tgactgctag cctttgttga cagacgtaga gtgacttctc ctgtcttggc ataaggggcc
     6901 aaggtaggat cgatctgatt atcaattaaa tcagccaaaa tcgtaaccaa ctggctctcg
     6961 ccaatcccaa agaaacgaag aactcgggaa tacagcttgc tccctgtcat caacttgggt
     7021 agaagttggt ttaagaccat gggtttcaat tcacttggcg gacctggaag gacgacatag
     7081 gtcactccgt ctacttctaa ttttcctcca acagccagtc ctgtttcgtt tggcagtgga
     7141 atcgctcctt ctacaatttg agcttgtctt tcgttattcg gtgttcgggc atagtctggt
     7201 cgcagggcaa aaaagatatc caacttctcc tgagcctgag gatcaaagac taatgctttc
     7261 cctaaaaatt tagctagggt ttgtttggtt aggtcgtcct cagttggccc caaaccgcct
     7321 gtcaaaatca ccagactgct acgttgactg gcaatctcaa gcaaagacaa gagacgaact
     7381 tcattgtctc ctacagccgt ctgaaaatat acatctaccc caatctcagc tagtttttcc
     7441 gacaaaaact gggcattggt gttgacaatc tgtcctgtca aaatctctgt tccaacagca
     7501 atgatttctg ctttcatgtt tcctcctacc tatctattcg tatttttttg aaaaaatcgc
     7561 aggaattttc ctacgattga tttttttatt tgtatcaaaa gttaattatc ttcatcacca
     7621 acaggtgctc tgccaaataa atcttcaaat aaaaccgcat tggtttcaag ctgagtaact
     7681 tcttcttgtc ccaaagaacg tcggagtata ttttgcattt ccaacatatg tgctctcgaa
     7741 acaatctggt aagaaacacc ttgaagtatc tctccttcac cctgcaactg ctgagtttca
     7801 atggttttaa atgaatcttt atagcctagc aagttaggga tactttttgc agacaaatca
     7861 atattggtct gcatattgtc actcaaagct tttagaatct cttgataatg accaacgcta
     7921 tttaaactga gagctttttc catgactttt tgaataactt cacgttgacg tttttgacga
     7981 ccataatccc cctcaggatc ttggtaacgc attcgtgcat agactagggc ttcttctccc
     8041 ccaatatgtt gctccccaac accgatagaa atagtattaa attcttcttg gtcactgata
     8101 gaaattggga aacctaggat attattgact gtaatacctc ctactgcatc cactagtttt
     8161 tgcaaccctc tcatattgac catcacatag cgatcaatat ggatattcat cattttttga
     8221 atggtttcta tagcaagctc tgctccacca tctgcatatg ctgagttcag tttcgcttca
     8281 tgagcctgac cattccctga ttcaatgcgc gtcagaatat cccgctctaa actcatcatt
     8341 gttgtttttt tcgttttagg attcactgtc atcaagatca tgctatcact tctaccgacc
     8401 caagtttcag ttcgttcaac atttccggtg tccactccca ttaacagaat ggttagaggt
     8461 tcagtcgctt caataacctt ggtttcttca ccgatttttt tataggtttt agctaaggtt
     8521 tctgtccctt gttgataaat agtataagca aaaacaccta ctcctactac agttacagaa
     8581 agtaaagcta gcaccattcc aataattttt ttaaccatat ttctactaac ctatcagttt
     8641 acccatcaag taaacatcga taaatttccc ttcttctata tatgccccac gctcttggct
     8701 accttcaatg acaaagccat gcttttgata aagatggact gctgcttgat tacgagtttg
     8761 gacagtcagt tggagacgac gcagaatgcc acttgcttgt gcccactcta tcgcttcttc
     8821 tagcaacaaa cttcccaagc cattattcca atatcttttt ccaatcacaa tgaagagttc
     8881 tccaatatga cggactctct tacgctggtc agctgtaata tttacaatac cagcaatttt
     8941 gccatttaag aatgcaagta aggttatctg attgtccgaa ctagcttgct tgttgaggaa
     9001 tatttccatc tcctcactag tcaagagaat accatctccg tctaggctgg taaagtctgt
     9061 ctccaaactc acacgattta aaaaggccac taattcagct gcatctttgg gctctgcttc
     9121 cctaatgagc aattcatact ccatattgaa gctcctctaa caatttctca gcacgcaaac
     9181 cctttgcctg aaaatttaaa cggcgtccat ctgcttcttt tagaatttcc aattctaaat
     9241 aagcatctgg caaggcatct cctaagagat tgccccactc aataacagtc acgccgccac
     9301 caaagataaa ctcatccaag tcgatagaat cagcatctcc ttcaatacga taaacatcta
     9361 ggtgataaag tggaagtcga ccttcatact ctctcacgat agtataggtg ggacttttaa
     9421 tcatttgaga aatctgtaat ccttttgcaa gtcctttagt aaaggtcgtt ttacctgcac
     9481 ccagttctcc agttaagatt aaaacatcat tctttgctaa tagatggccc aaacgctccc
     9541 ctaaggcttg caactcttct tcattttttg tgtacatact cttattatac caaaaacttt
     9601 tcttttgtgt ctattttcct actaaactta tcatcataac atccataaaa aacaggcttt
     9661 ctctaaaaga aaatgagcgt aacaatgacc aatacaagat ctcggaaaat atgaccataa
     9721 aaggaaactt ccttcttaac cgaatttggg acaagatagg ctgcaaaaaa caagcccagt
     9781 ccaatataaa tcagaagtga gacaatggtc attggatttc ttaagaaaag aagtgttgct
     9841 aaaatagtca ccaacactgt cttttttctg tctagcatag caagaaaatc gcgcacgtat
     9901 tttttcaagg gtaaaaaaat cagcaaatct agcccaaata ggaaaaagaa ggatggcaat
     9961 aaaaagtcaa ctaattcttg ctgcagcgta tttttgatga acaagttatc tgacaaaaca
    10021 agaacagctc ctaacaaatt aattaagagt aacatactgt aaaaaagctt cacagacttc
    10081 ttactggcta ggacactatg gacttcttgc ttacgggtat aaagataatt tactccagca
    10141 cagattcctg aaacgaaaac catgcttccg atgaaaaaaa ctgtactttg tttaaaggac
    10201 aagatgcatt ccttccatag gaaacagcta ctcaaactga tttgaattaa agctaacaaa
    10261 aataagattc tcattgattt catcttctct ctcccttcct accaatcatt atactaggag
    10321 aaaagagaga actgtttcta atcttctcaa atgtctcttt aagacgctaa acaaacacta
    10381 gagactaata ctcaatgaaa atcaaagatc aaactaggta gctagccaca ggttgctcaa
    10441 aacactgttt tgagattgca gatagagctg acgtgatttg aagagatttt cgaagaatat
    10501 aaatttgaaa tcatgaaaat ccgtcaaacg ggtggttgtt ttgtctcgca cctcacggag
    10561 cgagacggac tcagagtcac ataattataa ggctgatagt attaatctaa ctatcagcct
    10621 tacaggttat ttaacgtttc agaaaaacta taatgtcaag attaactaaa cagtatctaa
    10681 ttccttcaaa taattttcta tcttcatcaa cattaaagga ttgttataaa tcttacataa
    10741 ctctcttgct tctatataat aatttttgac ttgttctctg tctagaaatt tggctccagc
    10801 atttcctaca agaataagta gaggagccaa ttggtagctt gtctgtcttt gtttacagag
    10861 ttcaatcgtt tcaagagctt cttggatggc ttcattatat ttttcctttg atactaggta
    10921 gtgagcgtag ttgtaacgaa ctctgatgta gccaaataaa aactcttgat ggtccaaatt
    10981 ttttgtctga tacaactcta ttaaatgaga gtagtttgcc tcatattctt gttcacgacc
    11041 cactaaggaa tagaaattag atagagtatt caacgccttt aaataaatca gagtatttga
    11101 agagactttt aataatatat tttccaatga cgaaattgcc tcacacttac tgtcatattg
    11161 atagaagtca attatagatt taatccattc aaggtaagtt cggtcttcta atgttagaaa
    11221 agtgcttcgt tctacctcta ttttataaag atattctaaa tcgtcataat ttctgtcatc
    11281 taataggcga gcagatagat gtttgaaatt agagaggtta gacttaactt cgatttgttc
    11341 attgaaaaag taatccaaag ggacttcaag tcgttgagag agtttgaata acaagtctgc
    11401 ggagggaata aaatgacctc tttcaatttt actaatctgg ctttgttcac aaattccttc
    11461 tgcaagagtt tgttgggaga gtctcaactc ttttcttttc aatctgaatt tctctgcgag
    11521 tgtattcatt aaagataata aaccttccta tttgcttaat ttcattataa agtttttagt
    11581 tcaaaatagc aagttaaagg aataaataat tctttatggt aataaacaaa aaaaaaagtt
    11641 aaaaattaca taaaaatact tgactaaata aaatatatct gttagaataa aaacaaggaa
    11701 aaagaaaggg gtttcattgc atgagaaaaa aacgtggaat taaaaaatta gttacatttg
    11761 cattgctagg tgtttttatg tttagtaata caattcctta ccaacagttt attcagaaga
    11821 ataaacaatt ggagattcga gtgtaatcgc aaaagaagtc caatggtctt gatgttggga
    11881 aggctgatta aaacccgata ttttgcacga gaatgagaga attataattt atctgaaaaa
    11941 acgaaaaata tagagcaact tatttaactt tttataagga ggagttatta cttatgacca
    12001 actttaattc aaacgaaaaa ttttgtggaa aaagtttaaa atcattgtct gctgatgaaa
    12061 tgagtttaat ttatggtgca tctgatggtg cagagccacg ttggacgcct actcctatta
    12121 ttttgaaatc tgctgcagct agctcgaaag tatgcattag tgcagctgtt tctggtattg
    12181 gggggctagt tagctacaat aatgattgtt tggggtaaat taaaatgaaa aatgattttg
    12241 taatcggaaa gagtttgaaa gaattatctc ttgaagaaat gcaattggtt tatggtggca
    12301 cagatggtgc tgaccctaga tcaacaatta tatgttctgc tacattaagt tttattgcat
    12361 catatttggg gtcagctcag actcgttgtg gcaaagacaa caagaaaaaa taaaatattc
    12421 aattttaaaa ataaaagttg ctctttattt tcctctctcg taactaataa ttttgagaga
    12481 ggtttttttt taaaacaata
//
LOCUS       DAVKBK010000050        12495 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVKBK010000050 DAVKBK010000000
VERSION     DAVKBK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12495
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.050"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            31..752
                     /locus_tag="VWX69_001562"
                     /pseudo
     CDS             31..752
                     /locus_tag="VWX69_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            943..3234
                     /gene="pcrA"
                     /locus_tag="VWX69_001563"
     CDS             943..3234
                     /gene="pcrA"
                     /locus_tag="VWX69_001563"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU9192879.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNNLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            3277..3957
                     /gene="radC"
                     /locus_tag="VWX69_001564"
     CDS             3277..3957
                     /gene="radC"
                     /locus_tag="VWX69_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU9192880.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3954..4643)
                     /locus_tag="VWX69_001565"
     CDS             complement(3954..4643)
                     /locus_tag="VWX69_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9192881.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4661..5302)
                     /locus_tag="VWX69_001566"
     CDS             complement(4661..5302)
                     /locus_tag="VWX69_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU9192882.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(5385..5600)
                     /locus_tag="VWX69_001567"
     CDS             complement(5385..5600)
                     /locus_tag="VWX69_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9192883.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5608..5955)
                     /locus_tag="VWX69_001568"
     CDS             complement(5608..5955)
                     /locus_tag="VWX69_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU9192884.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5960..7075)
                     /locus_tag="VWX69_001569"
     CDS             complement(5960..7075)
                     /locus_tag="VWX69_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9192885.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(7085..8044)
                     /locus_tag="VWX69_001570"
     CDS             complement(7085..8044)
                     /locus_tag="VWX69_001570"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9192886.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(8157..8726)
                     /locus_tag="VWX69_001571"
     CDS             complement(8157..8726)
                     /locus_tag="VWX69_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU9192887.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8854..9525
                     /locus_tag="VWX69_001572"
     CDS             8854..9525
                     /locus_tag="VWX69_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU9192888.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            9509..10327
                     /locus_tag="VWX69_001573"
     CDS             9509..10327
                     /locus_tag="VWX69_001573"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU9192889.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            10324..11220
                     /locus_tag="VWX69_001574"
     CDS             10324..11220
                     /locus_tag="VWX69_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9192890.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            11264..12238
                     /gene="pta"
                     /locus_tag="VWX69_001575"
     CDS             11264..12238
                     /gene="pta"
                     /locus_tag="VWX69_001575"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU9192891.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3670 a         2393 c         2690 g         3742 t
ORIGIN      
        1 gttggtgttc agcgcacgac ttttgaagag atgttagctg tattaaaaac agcttatcaa
       61 cttaaacacg caaaaggtgg acgaaaacct aaattaagcc tagaagacct tcttatggcc
      121 actcttcaat atgtgcgaga atatcgaact tatgaagaaa ttgcggctgt ttttggtatc
      181 cacgaaagca acttaatccg tcggagctaa tgggttgaag taactcttgt tcaaagtggt
      241 gttacgattt caagaactcc tctcagctct gaggccacgg taatgattga tgcgacggaa
      301 gtaaaaatca atcgccctaa aaaaacaatt agcgaattat tcttgtaaaa aaatgccacg
      361 ctatgaaggc tcaagcgatt gtcacaagtc aagggagaat tgtttctttg gatatcactg
      421 tgaactattg tcatgatatg aagttgttca aaatgagttg cagaaatatc ggacaagctg
      481 gtaaaatctt ggctgacagt ggttatcaag ggctcatgaa gatatatcct caagcacaaa
      541 ctccacgtaa atccagcaaa ctcaagccgc taacagttga agataaagcc tgtaaccatg
      601 cgctatccaa ggagagaagc aaggttgaga acatctttgc caaagtaaaa acgtttaaaa
      661 taatttcaac aacctatcga aatcatcgta aacgcttcgg attacgaatg aatttgagtg
      721 ctggtattat caatcatgaa ctaggattct agttttgcag gaagtctatt gaggtattga
      781 gctagtttat gaaaaaattg ggtgaaaagt cgagtgtttt agaaacccac agtgtagtat
      841 tctagtttca atccactata ttttgctact ccccgtaaag tttctatttt ccctgatttc
      901 tgatataata gaaatattga cttcaagagt aaggaagaga agatgaacgc attattaaat
      961 ggaatgaatg accgtcaggc tgaggcggtg caaacgacag aaggtccctt gctaatcatg
     1021 gcaggggctg gttctggaaa gactcgtgtt ttaacccacc gtatcgctta tttgattgat
     1081 gaaaagctgg tcaatccttg gaatatcttg gccattacct ttaccaacaa ggctgcgcgt
     1141 gagatgaaag agcgtgctta tagcctcaat ccagctactc aggactgtct gattgcgacc
     1201 ttccactcca tgtgtgtgcg tattttgcgt cgcgatgcgg accatattgg ctacaatcgt
     1261 aattttacaa ttgtggatcc tggtgaacag cgaacgctca tgaaacgtat tctcaaacag
     1321 ttgaacttgg atcctaaaaa atggaatgaa cgaactattt tggggaccat ttccaatgct
     1381 aagaataatt tgattgatga tgttgcttat gctgcccaag ctggcgatat gtatacgcaa
     1441 attgtggccc agtgttatac agcctatcaa aaagaacttc gtcagtctga atccgttgac
     1501 tttgatgatt tgattatgct gaccttgcgt ctctttgatc aaaatcctga tgttttgacc
     1561 tactaccagc aaaaattcca atacatccac gttgatgagt accaagatac caaccacgct
     1621 cagtaccaat tggtcaaact cttggcttcc cgttttaaaa atatctgtgt ggttggggat
     1681 gcggaccagt ctatctacgg ttggcgtggt gctgatatgc agaatatctt ggactttgaa
     1741 aaggattacc ccaaagccaa ggttgtcttg ctggaggaaa attaccgctc aaccaaaacc
     1801 attctccaag cggccaacga ggttattaaa aataataaaa atcgccgtcc taaaaatctc
     1861 tggactcaaa acgctgatgg ggagcaaatc gtttactatc gtgccgatga tgagctggat
     1921 gaggctgtat ttgtagccag aaccatcgat gaacttagtc gcagtcaaaa cttccttcat
     1981 aaggattttg cagttctcta tcggactaat gcccagtccc gtacaattga ggaagccctg
     2041 ctcaagtcta acattcctta taccatggtt ggcggaacca aattctacag ccgtaaggaa
     2101 attcgcgata ttattgctta tctcaacctt attgctaatt tgagtgacaa tattagtttt
     2161 gagcgtatta tcaacgagcc taaacgtgga attggtctag gtacagttga gaaaatccgt
     2221 gattttgcaa atttgcaaaa tatgtctatg ctggatgctt ctgctaatat tatgttgtct
     2281 ggtatcaagg gtaaggcagc ccaatctatc tgggattttg ccaatatgat gcttgatttg
     2341 cgggagcagc tagaccactt aagcattaca gagttggttg agtccgtcct agaaaaaaca
     2401 ggttatgtcg atattcttaa cgcccaagcg actctagaaa gcaaggcacg ggttgaaaat
     2461 atcgaagagt ttctttctgt tacgaagaac tttgatgaca ccacggatgt gacagaagag
     2521 gaaactggtc tggacaaact gagtcgtttc ttaaatgact tggctttgat tgccgacaca
     2581 gattcaggta gtcaggagac atcagaagtg accttgatga ccctgcatgc tgccaaaggt
     2641 ctcgaatttc cagttgtctt tttgattggg atggaagaaa atgtctttcc acttagtcgt
     2701 gcgactgaag atccagatga attagaagaa gagcgccgtc tagcctatgt aggtatcacg
     2761 cgtgcagaga aaattctcta tctgaccaat gccaactcac gcttgctttt tggtcgtacc
     2821 aattataacc gtccgactcg ttttattaac gaaatcagtt cagacttgct tgagtatcaa
     2881 ggtctggctc gtcctgcaaa tacaagcttt aaggcatcat atagcagtgg tagtatttcc
     2941 tttggtcaag gtatgagttt ggctcaggct cttcaagacc gtaaacgcgg tgctgcccca
     3001 aaatcaatcc agtcaagcgg tcttccattt ggtcaattta cagctggcgc aaaaccagca
     3061 tctagcgagg caaattggtc cattggtgat attgctctcc acaagaaatg gggagaggga
     3121 accgttctgg aagtttcagg tagcggtgct aggcaggaat tgaaaatcaa tttcccagaa
     3181 gtaggtttga aaaaactttt agccagtgtg gctccaattg agaaaaaaat ctaattttcc
     3241 atccttctca cgaataataa agtgaggagg atttttatgt acagtatttc attccaagaa
     3301 gattcactat taccaagaga aaggctggcc aaggaaggag ttgaagcgct tagtaaccaa
     3361 gagttgctag ctattttact caggacagga acacgtcaag ttagcgtttt tgaaattgcc
     3421 caaaaagtct tgaacaatct ttcaagccta acggatttga aaaaaatgac cctgcaggaa
     3481 ttgcagagtt tgtctggtat tgggcgtgtt aaggccatag aattacaagc tatgattgaa
     3541 ctggggcatc gtattcacaa acacgagact cttgaaatgg aaagtattct cagcagtcaa
     3601 aagttggcca agaagatgca gcaggaatta ggggataaaa aacaagagca cctggtggca
     3661 ctctatctca atactcaaaa tcaaatcatc catcagcaga ccatttttat cgggtctgta
     3721 actcgtagta tcgctgaacc gcgagagatt cttcactatg caatcaagca tatggcgact
     3781 tctcttatct tggtccacaa tcatccttca ggagcggtag cgcctagcca aaatgatgat
     3841 catgtcacta aacttgttaa agaagcctgc gaattgatgg ggattgttct cttggaccat
     3901 ttgattgtct ctcattctaa ttactttagt tatcgtgaaa agacagattt aatctaaagt
     3961 tcattaacga catagtcaaa gagtttttta tctttgggac gattttcaaa aagaagttct
     4021 ggatgccatt ggacaccgag aaaggcgaca tcatccgtac tcatgacagc ctcaatgata
     4081 ccatctttag gatcatgagc cacaactttt aaatttggtg ctaagtcctt gatgctctgg
     4141 tggtggaagg agttgatatg agagatttct ccatagattt cttggagaac ggtatctggt
     4201 tctgttacca agcgttgagt tgtgtactca acagaagaat cctgccaatg gtcttcgata
     4261 tcttggtaca aagttccacc catggcaacg ttaaagagtt gggtaccacg gcagacagag
     4321 aaaatgggct ttttctgttt aatagcttcc ttgatgaggg tcagttcgaa gatatctctt
     4381 tgaaggtgat agtcatcgct atcaatggtt ttgggttcgc cataaaattt tggatcgaca
     4441 ttttgcccac ctgtcaagat gagcttgtca atcaaactga tatagtggca ggccatttct
     4501 tgatcaccaa tcggtaggat gatgggaatc cctccagcat ctttaacgcc ttcaacaaag
     4561 ccttttgctg cgtagctcat catgatgtca tcatctggat gagctttttc gtttcctgta
     4621 atcccaataa ctggtttttt cataaaatga ttttcgcttt ctaatcctct tttcgcatga
     4681 agtagaggag ggtttggagt tcacttgtca aatcgacata ctgaacgacc acgtcttttg
     4741 gtaaatgcag atggactggt gaaaaactga gaattccttt cacaccagca tcaaccaaga
     4801 gattagcaac ctcttgtgac ttgacgctgg gaacagttag gatagcagtc ttcacatcag
     4861 catccttgat tttatccttg atctgagaaa tcccgtaaat gggaatcccg tcaggagttt
     4921 gggtaccgac ttcaggatgg tcgtctaggt caaaggccat gataatcttc atcttgttac
     4981 gttcgtggaa gcggtagtgg agaagggcat ggcccatatt tccaatacca accagcatga
     5041 cattggtaat agagttgtca ttgagcaaat cggcaaaaaa tgtcattagt tttttgacat
     5101 catagccaaa accacgacga ccaagttcac caaaatagga aaaatcacga cgtacggtcg
     5161 ctgaatcaat accgatagcc tctgcaattt gcttagagtt ggcacgttca atcttttctg
     5221 catgaaatct cttaaaaatt cgatagtaga gagagagtct ttttgctgta gcttttggaa
     5281 tagcaaactg tttatctttc acaaaatcac aacctttcta ttcttctatt ttatagaaac
     5341 attgtgaaaa aatcaacaaa aataagaaaa aactaagaaa aatcttagtt ttgatgtaaa
     5401 aaatctgcat gagatagaaa acggtagagg tctccgacca gaccctgata aactttttgg
     5461 cccctaaaag tcagagaagt cacataaagt gtatctggta aggttacaca tcctgacaaa
     5521 gtcaacatga gagcctcatg atcctcatac ttgagagtac gctctacatg atagcagtcc
     5581 ttataggtca gttcaaacat tttggctcta tctttccgat tttgtaaaga caccacgttc
     5641 taccaagcta tccatgagga agtagaattt ttcctgatga atatggtggt cttctgattt
     5701 gaaaatatca actagacgaa ggccaaactt gtcagtgata ttgattttag cccctgtaag
     5761 ttccttgtta atgatgattt tgagttggaa gccttcaccg ctgtttggca ctttttccaa
     5821 aaggcgagtc agttcatagt taccaacctt agtttcaaaa aaggtgttat ctttgagggt
     5881 gaatttttta acagaagggc taagagtgta atcgtaacga caatttttta actgaatgat
     5941 tttttcaaat gccatatggc taacctccga taatttcttt taaggttttt gcgagggttt
     6001 gtaggtcttc aacggtattt tgtggcgaca aactgatgcg aagggattcc ttcaagcgtt
     6061 ctgaatttgc gccatacatg gcttcaagaa catggctgga ttggacaacg cctgcagtac
     6121 aggctgagcc agtagagatt gaaattccag ctaaatctag ccgaaggagt aagaggtcat
     6181 ttttctgacc aggaaatcca atattgagaa cataagggag atgatgtttt cctctattca
     6241 agtaatactg aatgccctcc agctctgcca gaaaggcagt ttctagattt tgtacatgtt
     6301 gaaaatgttc ttcttgtttt tctaggtctt cttttagggc tgcaaccatg cctacgatag
     6361 caggcagatt ttcagttcct gcacgttttt tctgttcctg gtctccgcca tgtagatagg
     6421 aatcaaagtc catgctagat gcgtagagaa aaccgattcc cttaggacca tggaatttgt
     6481 gggcagaagc agtgagaaaa tcaatgccca attcttctga atgaattggg attttaccaa
     6541 tagcctgaac tgcatcaaca tgataggcag cagggtgttg cttgagtatt tggccaattt
     6601 cagcgatggg cagtaggttt cctgtctcat tattggcaaa catggtagaa accaaaatcg
     6661 tatcgtcacg taaagccttt tgaatttgct gggctgtgat ttcttgattt tctggctgga
     6721 taatggttgc ttcaaaccca aagtgttgaa ccaagtaatc aattgtttca aggacagcat
     6781 ggtgctcgat ggcagttgtg atgatatgtt ttccttgttc ttggtgacga agacagtagc
     6841 caatgatggt agtattattg ccttcagtcc caccagaagt gaaaaagata tgttgaggtt
     6901 ttgtccttag taactgggct agttcctgac gggcttctcg caagagtttg ccagcttgac
     6961 gaccatgacc atgaatacta gaaggatttc cgtgggtttc ttgcataacc ttggtcatag
     7021 ctgaaatagc aactgctgac ataggagtcg ttgcagcatt gtccaaataa atcaaagaat
     7081 caccttattt ctttttattg taggcaaaga gtgggctgac tggttttctt tcgtgaatac
     7141 ggacgatagc atcaccaatt aactcactag cagtgatgta gcatacattt ttaggagttt
     7201 tttcttttgt tgctactgaa tcagtcacaa gaatttcttt aatattagta ttgtcaagaa
     7261 gctcagcagc tccctcgacg aagagaccgt ggctagaaac agcataaatt tctgtagctc
     7321 cttcacgttc aacgatttta gaagcttcag agaaggtacg tcctgtattt aaaatatcat
     7381 caatcaagat agctttctta ccttcaacat caccaataat ataaccttcg ttacgagttg
     7441 catcgtcttg agggtagtcg ataatggcga taggagcatc aagatattca gccaggctac
     7501 gcgcacgttt gacacctgaa tttttagggc taacgacaac aacatctgaa ccaagcaatc
     7561 ctttatcgca gtaatgtttt gcgaataggg gaacagtgaa aagattatcc actggaatat
     7621 caaagaaacc ttgaacctga acggcatgca aatcaagagt caggatacga tcaactccag
     7681 ccttaaccag catattggca actagttttg ctgtaagtgg ctcacgagga caagcaatgc
     7741 ggtcttgacg tgcatagcca aaatatggaa ggacaacgtt gatactgtgg gcacttgcac
     7801 gcacacaagc atcgaccatg attaacaatt ccattaggtg gttgttgaca gggaaacttg
     7861 ttgattgtat gatgtaaaca tcataaccac ggacactttc ttcgatattt acttggattt
     7921 ctccgtctga aaattgacgt gatgatagtt ttccaagtgg gacaccaaca gcttgggcaa
     7981 ttttttgtgc aatctcttgg ttagagttga gtgcgaaaag tttcatgttt tttctatctg
     8041 acattataga ccgtcctctg taaactttat aaatcctagt tatatttacc ttacatatat
     8101 gaactgggat ttgtgtattt ttatcttttc tattttacca aaaaatggag attatttcag
     8161 ctatttttca tacttttgac aaatcgaacc aattttgaag gagctttttg gtaggaaatc
     8221 tgatttttct ctaaaaattg tcggaaatcc tgtttgcctt gctcatgatt ttccacttca
     8281 agctccaatt cgtaatctgt tatatcaaag tatcggctct gatccagtgc catgagacca
     8341 atagctgttt tcatttcata gcgaagcgtt gttagacaac caagaacctg ccagttctta
     8401 ctttggatac catgtttcgc caattcatcc agtactagcc cttgaggaag ttcttcctta
     8461 ctcagatagt tctcagcatc ttttagttgc aatttttggt tgtattccat gtttccaaca
     8521 ctctgcggga ctttgagtgt caactcagcc cagtcttcaa aggttcgaat gcgcatagcg
     8581 actttctttt ctcgcagttc aaaatcaggc gtgtcgatgt agtaatttgt ttgaagaaca
     8641 ggagtgacac ctgtgaactg gtcttttaga cgattgtatt catctttttt caatagtgtt
     8701 ttcaattcaa tttctaaatg tttcattttt cttacctttt tttatcgttg aaagcggatt
     8761 tatggtataa taagcattgt atttattgta tatgaatctg gagaaaaaat caaagatatt
     8821 tttgacggat aatatgagaa caagggagaa tatatgacct tagaatggga agaatttcta
     8881 gatccttaca ttcaagctgt tggtgagtta aagattaaac ttcgtggtat tcgtaagcaa
     8941 tatcgtaagc aaaataagca ttctccaatt gagtttgtga ccggtcgagt taagccaatt
     9001 gagagcatca aagaaaaaat ggctcgtcgt ggcattactt atgcgacctt ggaacacgat
     9061 ttgcaggata ttgctggctt acgtgtgatg gttcagtttg tagatgacgt caaggaagta
     9121 gtggatattt tgcacaagcg tcaggatatg cgaatcatac aggagcgaga ttacattact
     9181 catagaaaag catcaggcta tcgttcctat catgtggtag tagaatatac ggttgatacc
     9241 atcaatggag ttaagactat tttggcagaa attcaaattc gtactttggc catgaatttc
     9301 tgggcaacga tagaacattc tctcaactac aagtaccaag gggatttccc agatgagatt
     9361 aagaagcgac tggaaattac agctagaatc gcccatcagt tggatgaaga aatgggtgaa
     9421 attcgtgatg atatccaaga agctcaggca ctttttgatc ctttgagtag aaaattaaat
     9481 gacggtgtag gaaacagtga cgatacagat gaagaataca ggtaaacgaa ttgatctgat
     9541 agccaataga aaaccgcaga gtcaaagggt tttgtatgaa ttgcgagatc gtttgaagag
     9601 aaatcagttt atactcaatg ataccaatcc ggatattgtc atttccattg gcggggatgg
     9661 tatgctcttg tcggcctttc ataagtacga aaatcagctt gagaaggtcc gctttatcgg
     9721 tcttcacact ggacatttgg gcttctatac agattatcgt gattttgagt tggacaagct
     9781 agtgactaat ttgcagctag atactggggc aagggtttct taccctgttc tgaatgtgaa
     9841 ggtctttctt gaaaatggtg aagttaagat tttcagagca ctcaacgaag ccagcatccg
     9901 caggtctgat cgaaccatgg tggcagatat tgtaataaat ggtgttccct ttgaacgttt
     9961 tcgtggagac gggctaacag tttcgacacc gactggtagt actgcctata acaagtctct
    10021 tggcggtgct gttttacacc ctaccattga agctttgcaa ttaacggaaa ttgccagcct
    10081 taataatcgt gtctatcgaa cactgggctc ttccattatt gtgcctaaga aggataagat
    10141 tgaacttatt ccaacaagaa acgattatca tactatttcg gttgacaata gcgtttattc
    10201 tttccgtaat attgagcgta ttgagtatca aatcgcccat cataagattc actttgtcgc
    10261 gactcctagc cataccagtt tctggaaccg tgttaaggat gcctttatcg gtgaggtgga
    10321 tgaatgaggt ttgaatttat cgcagatgaa catgtcaagg ttaagacctt cttaaaaaag
    10381 cacgaggttt ctaagggatt gctggccaag attaagtttc gaggtggagc tattctggtc
    10441 aataatcaac cgcaaaatgc aacgtatcta ttggacgttg gagactacgt taccattgac
    10501 attcccgctg agaaaggctt tgaaaccttg gaggctattg agcttccatt agatattctc
    10561 tatgaggatg accactttct agtcttgaat aaaccctatg gagtggcttc tattcctagt
    10621 gttaatcact ctaataccat tgccaatttt atcaagggtt actatgtcaa gcaaaattat
    10681 gaaaatcagc aggttcacat tgttaccaga ctagataggg acacttctgg cttgatgctc
    10741 tttgccaagc acggttatgc ccatgcacga ttagacaagc agttgcagaa gaaatctatc
    10801 gagaaacgct actttgcttt ggttaaggga gatggacatt tggaaccaga aggggaaatt
    10861 attgctccga ttgcgcgtga tgaagattcc attattacca gacgagtggc taaaggcgga
    10921 aagtatgccc atacttcata caagattgta gcttcttatg gaaatattca cttggtctat
    10981 attcacctgc acactggtcg aacccatcaa atccgagtcc atttttctca tatcggtttt
    11041 cctttgctgg gagatgattt gtatggtggt agtctggaag atggtattca acgtcaggct
    11101 ctgcattgcc attacctatc cttttatcat ccatttttag agcaagactt gcagttagaa
    11161 agtcccttgc cggatgattt cagtaacctt attacccagt tatcaactaa tactctataa
    11221 aaactgtctc agagtataat tattatctta aaggagaaaa ctcatggaag tttttgaaag
    11281 tctcaaagcc aaccttgttg gtaaaaatgc tcgtatcgtt ctccctgaag gggaagagcc
    11341 tcgtattctt caagcaacaa aacgcttagt aaaagaaaca gaagtgattc ctgttttgct
    11401 tggaaatcct gaaaaaatta aaatttatct tgaaattgaa ggaatcatgg atggttatga
    11461 ggtcatcgac cctcaacatt atcctcaatt tgaagaaatg gtttctgcct tggtggagcg
    11521 tcgcaagggc aaaatgactg aagaagatgt acgcaaggtt ttggttgaag atgtcaacta
    11581 ctttggtgtg atgttggttt acttgggctt ggttgatgga atggtgtcag gagcgattca
    11641 ctcaacagct tcaacagttc gcccagctct acaaatcatc aaaactcgtc caaatgtaac
    11701 tcgtacttca ggagccttcc tcatggttcg tggtacggaa cgttacctat ttggagactg
    11761 tgccattaat atcaatccag atgcagaagc cttggctgaa attgccatca actcagcaat
    11821 cacagctaag atgtttggca tcgaacctaa aattgccatg ttgagctatt ctactaaagg
    11881 ttcagggttt ggtgaaagcg ttgataaggt cgttgaagca actaaaattg ctcacgactt
    11941 gcgtcctgac cttgaaatcg atggtgagtt gcaatttgat gcggcctttg ttcccgaaac
    12001 tgcagctctg aaagctccgg gaagtacagt agctggtcaa gcaaatgtct tcatcttccc
    12061 aggtatcgag gcaggaaata tcggttacaa gatggctgaa cgcctgggtg gctttgcggc
    12121 tgtaggacct gttttgcaag gtttaaacaa gccagttaat gatctttctc gtggatgtaa
    12181 tgcagatgat gtttacaagt tgaccctcat cacagcagct caagcagttc atcaatagtg
    12241 aaaactataa agtgatatac tatgctatac tgtagttatg aaactatgta cgaaaagcac
    12301 tgccattaat tcctgagaac taaattactg attggtgtca aaaaggaaaa cttccaagcg
    12361 atgatatcct gtctatacac gacctataga aatctgtaat atacatatcc gtaaaacgat
    12421 aaattccctt tttgatttta aatgagtatg aaaagagaat tttttggctc tttgtcaact
    12481 gtagtgggtt gaagt
//
LOCUS       DAVKBK010000051        12362 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVKBK010000051 DAVKBK010000000
VERSION     DAVKBK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.051"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            46..315
                     /gene="blpJ"
                     /locus_tag="VWX69_001576"
     CDS             46..315
                     /gene="blpJ"
                     /locus_tag="VWX69_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEU9192892.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            384..632
                     /gene="blpK"
                     /locus_tag="VWX69_001577"
     CDS             384..632
                     /gene="blpK"
                     /locus_tag="VWX69_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HEU9192893.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            876..1025
                     /gene="blpO"
                     /locus_tag="VWX69_001578"
     CDS             876..1025
                     /gene="blpO"
                     /locus_tag="VWX69_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU9192894.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1129..1248
                     /locus_tag="VWX69_001579"
     CDS             1129..1248
                     /locus_tag="VWX69_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU9192895.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            1716..2087
                     /locus_tag="VWX69_001580"
     CDS             1716..2087
                     /locus_tag="VWX69_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192896.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLTSIL
                     VTVYLTREMRLREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            2716..3099
                     /locus_tag="VWX69_001581"
     CDS             2716..3099
                     /locus_tag="VWX69_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU9192897.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3151..3840
                     /locus_tag="VWX69_001582"
     CDS             3151..3840
                     /locus_tag="VWX69_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9192898.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            3882..4115
                     /locus_tag="VWX69_001583"
     CDS             3882..4115
                     /locus_tag="VWX69_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192899.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4266..4877
                     /locus_tag="VWX69_001584"
     CDS             4266..4877
                     /locus_tag="VWX69_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9192900.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            5038..5832
                     /locus_tag="VWX69_001585"
     CDS             5038..5832
                     /locus_tag="VWX69_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU9192901.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5829..6464
                     /gene="trmB"
                     /locus_tag="VWX69_001586"
     CDS             5829..6464
                     /gene="trmB"
                     /locus_tag="VWX69_001586"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU9192902.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6590..7069
                     /gene="rimP"
                     /locus_tag="VWX69_001587"
     CDS             6590..7069
                     /gene="rimP"
                     /locus_tag="VWX69_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU9192903.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7113..8249
                     /gene="nusA"
                     /locus_tag="VWX69_001588"
     CDS             7113..8249
                     /gene="nusA"
                     /locus_tag="VWX69_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU9192904.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8271..8564
                     /locus_tag="VWX69_001589"
     CDS             8271..8564
                     /locus_tag="VWX69_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU9192905.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8557..8856
                     /locus_tag="VWX69_001590"
     CDS             8557..8856
                     /locus_tag="VWX69_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU9192906.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8873..11665
                     /gene="infB"
                     /locus_tag="VWX69_001591"
     CDS             8873..11665
                     /gene="infB"
                     /locus_tag="VWX69_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU9192907.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11916..12266
                     /gene="rbfA"
                     /locus_tag="VWX69_001592"
     CDS             11916..12266
                     /gene="rbfA"
                     /locus_tag="VWX69_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU9192908.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3771 a         2126 c         2782 g         3683 t
ORIGIN      
        1 ttaagacttt ggtaacaaat tgaaaataaa aaggaggtat tcatcatgaa tacaaaaatg
       61 ttgtcacagt tagaggttat ggatactgaa atgcttgcga aagttgaagg ggggtatagc
      121 tccactgatt gtcaaaatgc actgattaca ggagtcacta cgggaattat aactggtgga
      181 actggagcag gtttggccac tttaggagta gctggacttg ctggtgcatt tgttggagca
      241 cacattggtg caattggggg tggattaaca tgcttaggag gtatggttgg tgataaattg
      301 ggactaagtt ggtaagactt atagtaaaat tatgaggatt ctattctgat ttattttagt
      361 tttttaaaaa aggagtattt gtcatggata caaaaatgat gtcacaattt tctgttatgg
      421 atactgaaat gcttgcttgc gttgaaggtg gcggatgcaa ttggggagat tttgccaaag
      481 caggtgttgg aggagcagct gtagttgctg ctttaggttg tgcagcgggt ggagtgaaat
      541 atgggaaaat tctaggacca tggggcgctg caataggagg aattggagga gcagtggttt
      601 gtggatattt agcctatacc gctacatcat aaaaatgaaa gctaaatttt atgaaggcta
      661 tattctttat tattctcttc gcttttcaaa cctatcttat ttatctatcc ataagtatct
      721 ctgataaaaa acaaaagact attgaattaa catcattgaa ttgttttgtc atattatttc
      781 taatctatga taaattaatt tttctcttta ttgcctatgt ttttttgata atttttatat
      841 taaacttgtt ccgtaactga aaagtgacat actatatgaa tacaaaaatg atgtcacaat
      901 tttctgttat ggataatgaa atgcttgctt gcgttgaagg tggagatatt gattggggaa
      961 gaaaaattag ttgtgcagca ggggttgcat atggcgcaat tgatgggtgt gcaacaacgg
     1021 tttgacattt ctattgggac catttgctat aggaataggt gtaactggtg ctgcaggtgg
     1081 agctatactt ggaggtgtag cctatgcagc aacatgttgg tggtaattat ggattttaaa
     1141 agttttatta ttggtttagt agttggtata tttggtcctt atatggatga cttaattaga
     1201 aaaatatttt caaaatcttc caaaaaggat acggatagta ctctctaaaa aataaatttc
     1261 tcccctgtat ttgctagctt aatttacagg ggagtttctt taatattgtt tcgcctgtca
     1321 aaatgatatg tgatagcagg atgaaaagtc tacaaacaag ttggtatcaa tacaatataa
     1381 agaggaaagt atgtttttca tgcttgcttt tttaattttt acaattcaag aggttttgat
     1441 gaccatttat gatttgagtg atccaaggtc aaaataagtg ctatactagc agtgtaaatg
     1501 ttcttgctca actaagataa atcgcacatt taggaggaaa acttatgaag aaaaaaatac
     1561 tgattatttt cgttctgtat ctgatcatgt ccatctttct ttatccgctt agggagagta
     1621 tttggtataa tctattttat accatagcct atatgattgc ggttatgatc tatttttctt
     1681 taattaaaaa gaaagaaaag aaatgaaaga ttttcttgat taaaaagaat catattcttt
     1741 gtgagattgt tcctgggtca gttgcctttg cttgtttcta cttatctatt tctatttcgt
     1801 cagttttcca atttctttta gtagttatta acttgacttc tattttggtt actgtttatc
     1861 ttactaggga aatgagatta agagagtttg aagatgatga tttggttagt cctagaacca
     1921 atcaactcat gtttatcggc ttgacaggct ttatgtctat tatttgtttg tatagaggta
     1981 tcacagcagg agaatcttat caacaactaa tcgcttatat tggtgctatt ctttgcttga
     2041 tcatcatgct tctactcatt tggggtttga agtattataa aaagtagggg ctaatgaagt
     2101 ttttgcaatt taggaggttt cgatgacaat tcaagatttg gatgaaaaat tttaaaaaac
     2161 aatgatatac taaacttgtc aaagttgcaa cgggtgctgc tacattatgt taaaaatcgc
     2221 tcttgattga taagttggat ttgttaggaa aggagtaaat aattatggat aagaaaaaga
     2281 tagtttcgac tataatatgt atagtatttc ttgtagtgtc agtagataat ttttttagag
     2341 acttaacccc gttactgttc attttaaata ttattggcct gtcttgcttt tcagtgctaa
     2401 catacattaa cataaaagag atactcttaa atataagtaa atgatgattt ggttagtcct
     2461 agaaccaatc aacttatgtt tatcggcttg gcagatttta tgtttgtcat ttgtttgtat
     2521 agaggtattt cagaaacaga attctatcaa caactaatcg cttatatagg tgtattctct
     2581 gcttgtttat cacgcttctg ctcatgtggg gcttgaagta ttataaaaag tagctttcta
     2641 tccttttctg acaggatatt tgagtagaag gctctattaa attgttagtg aaataaatga
     2701 atggaggtat ttaatatgaa atacagatta ttttttgtta ttttcttgag tagtgtgttg
     2761 gatattcttt tagggacatt tttacaaatc tctatcgtat ctattgggtg gcttgttctt
     2821 tacagtggtt tgtttgaagc aggagttttc cttcttgcta ataaaggggt ggcggtaaaa
     2881 atcaaggaag tagatattcg aaatcgcttt aaatttattt ttggaaaaac cttatggttt
     2941 caaattcttt tgctcatctt tttgataatc aaactttatc ttggtttgga tgcgaggttg
     3001 attttattct atggacatat tttcattgtc tttaatgcct taatgtatct attatctagt
     3061 agtcaggtta gccttaaaaa aaacaaactg tcttcttaat cttacagcag tagagcctga
     3121 caaggtgagg tcatagtagg gaggatttct atgaaaaagt atcaacttct attcaaaata
     3181 agtgcagttt tctcttactt atttttcgta tttggtcttt ctcagatgac gcttattatt
     3241 caaaattatt ggcaattttc ttcccagatt ggcaatttcg tctggattca aaatttcttg
     3301 agtttgctat ttagcggagt catgatttgg attctggtta agacaggtca tggttatctc
     3361 tttcacattc caagaaaaaa atggctttgg tattcgattt tgacagtatt agtggtagtg
     3421 ctccagatct cttttaacgt tcagacagct aaacatgttc agtcaactgc tgaaggttgg
     3481 gctgtattga tcggttatag tgggaccaac tttgctgagc taggtatcta tataactttg
     3541 ttctttctga ctccacttat ggaagagcta atctatagag gattactgca acacgccttt
     3601 tttaagcatt cgagatttgg ccttgatttg cttcttccgt caattttatt tgctcttcct
     3661 catttttcaa gcctgcctag tttgttagat atcttcatct ttgcaacatc tggcatcatc
     3721 tttgctagtt tgacccgcta taccaagagc atttatcctt cctatgcggt gcatgtgatc
     3781 aataatattt tcgcaacatt accatttttg ctgacttttt tacatagggt cttggggtaa
     3841 aaaaacaaaa ggcttgcttt tcagccatag aggagattat catgtataaa cacttatttt
     3901 tcctagattc caaaacttta gatcggttga caccctatat tctagtcttg gcttctgaca
     3961 ccattgcttt taatgttttt gtgctaacct ttgtatctgc ggtggttttt aatttcctaa
     4021 attccatgct agctttaatg gctatattca taggggctgg ctatgtggtc ggattttggt
     4081 tactaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg ctgtacttga
     4141 gtacggcaag gcgacgttga cgtggtttga atttgatttt cgaagagtat aaaatggttt
     4201 gttttggaaa ggctagaact aaagaatgac gcgtaggaag tctgtttggt gaggaggata
     4261 gttttatgga gttttttgat aaatttcatg ccttgtgttt tggattttta gtactaataa
     4321 ttgtcattac agttccttat acgattaacc atgggggttt ttttcaaaat gaatctgcat
     4381 tgattcttgt aagtcttctt gtaacctcgc tgagtgttgc ttatgctaga aagtttgaaa
     4441 tgatttcttt tgggatgtta agcaagaaac aacttttgct tttcattgca atctttcttc
     4501 taagtgtact tgagacgctg gtttatattc atttcttcgc tgtttcttct ggctcagggg
     4561 tccaacactt ggcggaagtc agcagaggaa tttccctgtc tttgattttg actacctcag
     4621 tttttggccc catccaggag gaactcattt tcagaggact tcttcaaggt gcggtttttg
     4681 acaattcttg gttagggctt gtgctaactt cctctctctt ttctttcatg catggacctt
     4741 ctaatgtccc ttcgtttatt ttttatctac ttgggggttt gttgctgggc tttgcttata
     4801 aaaagagtca aaacctatgg gtttctactc tagtccacat gttttacaac agttggccac
     4861 tcctatatta tttataaaaa ttatgaaaag gtaagcagaa gatggtgctt acctttttca
     4921 agctataatg atacccaagc caatccagag gcttttcttt gagaatcggg ttagagtggt
     4981 tgacgaatag gccaaaaact agtagaatag taaggaaact ttatacggag gaaagaaatg
     5041 gatttgggtg ataatgagct aacactgact cccatacctg ggaaaagtgg caaggcttat
     5101 atgggtagct atcctgacgg gaagcgcatc tttgtaaaaa tgaacacctc tccaatccta
     5161 cctggtctag ctagagaaca aattgctcca caattattat ggagtcgtcg tttggcagat
     5221 gggcgtgata tgtgtgctca agaatggttg acaggcaaga tattgacccc ctatgatatg
     5281 aatcgtaagc aaatcgtcaa tattttaacc cgtcttcatc gctcacgtcc gttgatgaca
     5341 caattgagtc gtttgggcta tgccatggaa acacctgtag atttactaca gtcttggcag
     5401 gaaacggctc cagatgcttt gcgtaaaaat cattttatca gtgaagtgat ggctgattta
     5461 cgtcagacta ttccaggatt tagagaggac catgcgacca ttgtccatgg agatgtacga
     5521 catagtaatt ggattgagac agatagtggc ttgatttatt tagtagattg ggattcggtt
     5581 cgcttgaccg atcgcatgtt tgatgtggcc catatgctct gccattatat ttcagaacat
     5641 cagtggaagg aatggttgac ctactacggt tacaagtaca atcaaacggt attaagtaaa
     5701 ttgtattggt atggtcaatt gtcttatttg agtcagattt ccaagtatta tatgaaccaa
     5761 gatttagaaa atgtcaatcg ggagattcat ggtttgcgtc atttccgaga caagtatgga
     5821 aagagaagat gagagttaga aatcgtaaag gggcaacaga attactagag gcaaatcccc
     5881 agtatgtggt cctcaatccc ttggaagcca aggcaaaatg gcgggacttg tttggcaatg
     5941 ataatcccat tcatgtggaa gttggaagtg gaaagggtgc ctttgtttca ggtatggcca
     6001 agcaaaaccc tgacatcaac tatatcggga ttgatattca aaagtctgtt ttgagctacg
     6061 ctttggacaa ggtgcttgaa gttggagtgc ctaacatcaa gctcttgtgg gtagatggtt
     6121 ctgacttaac tgactatttt gaagacggtg agattgatcg cttgtatctg aacttttcag
     6181 atccatggcc gaaaaaacgc catgaaaagc gtcgtttgac ctacaagacc ttcttggata
     6241 ccttcaaacg tatcttgcct gaaaatggag aaattcattt caagacggat aaccgtggct
     6301 tgtttgagta cagtttagtg agcttttctc aatatggcat gaaactcaat ggtgtctggt
     6361 tagatttgca tgccagtgat tttgaaggca atgtcatgac agaatacgag caaaaattct
     6421 caaacaaggg gcaagttatc taccgagttg aggcagaatt ttaagagata gcctaaaatt
     6481 aggctgtaca agtgcttttg ctttacataa gttggcaaac gtgctatact gatagtaaga
     6541 atatgaaaag tgaggcgggg aaatatcttc gcctcttgct tatgaggagg tggacgcaat
     6601 cgcaacaatc gtagaattag tcagagaagt tgtagaacct gtcatagaag ctccttttga
     6661 actcgtggat atcgagtatg gaaagattgg cagtgacatg attctcagta tttttgtaga
     6721 taaacccgaa ggaattacct tgaacgacac ggcagacttg acagaaatta tcagtcctgt
     6781 cctagacacc atcaagccag atcccttccc agaacaatat ttcctagaaa ttaccagtcc
     6841 aggtttggaa cgccctttga aaaccaagga tgccgtcgct ggagcggttg gaaaatacat
     6901 ccatgtcggg ctctaccaag ccatcgataa gcaaaaggtc tttgaaggaa ccttgttggc
     6961 cttcgaagag gacgagttga ctatggaata tatggacaag acgcgtaaga aaaccgtcca
     7021 aattccatac agtttagtat caaaagcacg tttagcagtt aaattataga aaaagaaagg
     7081 atagcttttg aggattcaaa agtgaagaaa acatgagtaa agaaatgcta gaggccttcc
     7141 gcattttgga agaagacaag ggaatcaaaa aagaagatat catcgacgca gtagtagagt
     7201 cgcttcgttc cgcttatcgc agacgctatg gtcagtcaga cagcgtagct attgacttca
     7261 acgaaaaaac aggtgacttt acagtttata ctgtccgtga agttgttgat gaagtatttg
     7321 atagccgttt ggaaatcagc ttgaaagatg ctcttgccat taattcagct tatgaacttg
     7381 gagacaaaat caagtttgaa gaagcaccag ctgagtttgg tcgtgtagca gcccagtctg
     7441 ccaaacaaac catcatggaa aaaatgcgca agcaaacacg tgccatcact tacaatactt
     7501 acaaagaaca tgagcaagaa atcatgtctg gtacagtaga acgctttgac aaccgcttta
     7561 tctatgtcaa ccttggtagc atcgaagccc aattgtcaaa acaagaccaa attcctggag
     7621 aagtttttgc ttctcatgat cgtatcgaag tttatgttta caaggttgaa gacaaccctc
     7681 gtggtgtgaa cgtctttgtt agccgtagtc atccagaaat gatcaaacgt ttaatggagc
     7741 aagaaattcc agaagtttat gatggaactg ttgaaatcat gagcgtggct cgtgaagcag
     7801 gtgaccgtac gaaggttgct gttcgtagcc acaatccaaa cgtggatgct atcggtacaa
     7861 tcgttggacg tggtggtgct aatatcaaga agattactag caaattccac ccagctcgtt
     7921 acgatgctaa aaatgaccgc atggtaccaa tcgaagaaaa tatcgatgtt atcgagtggg
     7981 tagcagatcc agctgaattt atctacaatg ccatcgctcc tgctgaggtt gaccaagtta
     8041 tctttgatga aaacgacagc aaacgtgcct tggtggttgt tccagataac aagctttctc
     8101 ttgccattgg tcgtcgtgga caaaacgtgc gcttggcggc tcacttgact ggttaccgta
     8161 tcgatatcaa gtctgctagc gaatttgaag ccatggaaga cgctgcttca gtagagttgg
     8221 aagtagaaaa cgatactgta gaagaataaa agctgctaga ggagggaaag atgaaaacaa
     8281 gaaaaatccc tttgcgcaag tctgttgtgt ctaacgaagt gattgataag cgtgatttgc
     8341 tccgcattgt caagaacaag gaaggacaag tctttattga tcctacgggc aaggccaatg
     8401 gccgcggcgc ttatatcaaa ctagacaatg cagaagccct agaggcgaaa aagaagaagg
     8461 tctttaaccg cagctttagc atggaagtgg aagaaagctt ttatgacgag ttgatcgctt
     8521 atgtggatca caaagtgaaa agaagagagt tgggacttga ataagcaaaa gataagtaat
     8581 ctcttggggc ttgctcagcg agcagggcgc atcatatcgg gtgaagaatt ggtggtcaag
     8641 gccattcaag acggcaaggc caagttggtc tttctagctc atgatgctgg acccaatctg
     8701 accaagaaga ttcaagataa aagtcattat tatcaagtag aaattgtaac cgtgttttca
     8761 acactggaat taagcatagc agtcgggaaa tcgagaaagg ttttggctgt aacagatgct
     8821 ggatttacaa agaaaatgag gtctcttatg gaatagaaga ggaggacatg atttgtctaa
     8881 gaaaagattg tacgaaatcg caaaagaact tggaaaagaa agtaaagaag ttgtagcgcg
     8941 tgcaaaagag ttgggcttgg atgtgaaaag ccactcatca agtgtggaag aagctgtcgc
     9001 tgcaaaaatt gctgccagct ttaagcctgc agctgctccg aaagtagaag caaaacctgc
     9061 agcaccaaaa gtaagtgcag aaaagaaagc cgaaaaatct gagccagcta aaccagctgt
     9121 agctaaggaa gaggcaaaac cggctgagcc agttgctccg aaaacagaaa aagtagcagt
     9181 gaaaccgcaa agtcgtaatt tcaaggctga gcgtgaagcc cgtgctaaag agcaggcaga
     9241 acgacgcaag caaaataagg gcaataaccg tgaccaacaa caaaacggaa accgtcagaa
     9301 aaacgacggc cgtaatggtg gaaaacaagg tcaaagcaac cgcgacaatc gtcgctttaa
     9361 tgaccaagct aagaagcagc aaggtcagca aaaacgtaga aatgagcgcc gtcagcaaga
     9421 ggataaacgt tcaaatcaag cggctccacg tattgacttt aaagcccgtg cagcagccct
     9481 aaaagcagag caaaatgcag agtacgctcg ttcaagtgag gaacgcttca agcagtatca
     9541 ggctgctaaa gaagccttgg ctcaagctaa caaacgcaag gaaccagagg aaatctttga
     9601 agaagcggct aagttagctg aacaagcaca gcaagttcaa gcagtggttg aagtcgtccc
     9661 tgagaaaaaa gaacctgcag tggatacacg tcgtaaaaaa caagctcgac cagacaaaaa
     9721 tcgtgacgat tatgatcatg aagaagatgg tcctagaaaa caacaaaaga atcgaagtag
     9781 tcaaaatcaa gtgagaaatc aaaagaatag taactggaat aacaacaaaa agaacaaaaa
     9841 aggcaataac aagaacaacc gtaatcagac tccaaaacct gttacggagc gtaaattcca
     9901 tgaattgcca acagaatttg aatatacaga tggtatgacc gttgcggaaa tcgcaaaacg
     9961 tatcaaacgt gaaccagctg aaattgttaa gaaacttttc atgatgggtg tcatggccac
    10021 acaaaaccaa tccttggatg gggaaacaat tgaactcctc atggtggatt acggtatcga
    10081 agccaaacaa aaggttgaag tggataatgc tgacatcgaa cgtttctttg tcgaagatgg
    10141 ttatctcaat gaagatgaat tggttgagcg tccaccagtt gttactatca tgggacacgt
    10201 tgaccacggt aaaacaaccc ttttggatac tcttcgtaac tcacgtgttg cgacaggtga
    10261 agcaggtggt attactcagc atatcggtgc ctaccaaatc gtggaaaatg gtaagaagat
    10321 taccttcctt gatacaccag gacacgcggc ctttacatca atgcgtgcgc gtggtgcttc
    10381 tgttaccgat attacgatct tggtcgtagc ggcagatgac ggggttatgc ctcagactat
    10441 tgaagccatc aaccactcaa aagcagctaa cgttccaatc atcgtagcta ttaacaagat
    10501 tgataaacca ggtgctaacc cagaacgcgt tatcggtgaa ttggcagagc atggtgtgat
    10561 gtcaaccgct tggggtggag attctgaatt tgttgaaatc tcagctaaat tcaaccaaaa
    10621 tatcgaagaa ttgttggaaa cagtccttct tgtagctgaa atccaagaac tcaaggcaga
    10681 cccaacagtg cgtgcaatcg gtacggttat cgaagcgcgc ttggataaag gaaaaggtgc
    10741 ggtcgcaacc cttcttgtac aacaaggtac cttgaatgtt caagatccaa tcgttgtcgg
    10801 aaataccttc ggtcgtgtcc gtgctatgac caacgacctt ggtcgtcgtg ttaaagttgc
    10861 tggaccatca acaccagtct ctatcacagg tttgaacgaa gcaccgatgg cgggtgacca
    10921 ctttgccgtt tacgaggatg aaaaatctgc gcgtgcagca ggtgaagagc gtgccaaacg
    10981 tgccctcatg aaacaacgtc aagctaccca acgtgttagc cttgaaaacc tctttgatac
    11041 ccttaaagct ggggaactca aatctgttaa tgttatcatc aaggctgatg tacaaggttc
    11101 tgttgaagcc ctttctgcct cacttcaaaa gattgacgtg gaaggtgtca aagtgactat
    11161 cgtccactca gcggtcggtg ctatcaacga atcagacgtg acccttgccg aagcttcaaa
    11221 tgcctttatc gttggtttca acgtacgccc tacaccacaa gctcgtcaac aagcagaagc
    11281 tgacgatgtg gaaatccgtc ttcacagcat tatctacaag gttatcgaag agatggaaga
    11341 agctatgaaa gggatgcttg atccagaatt tgaagaaaaa gttattggtg aagcggttat
    11401 ccgtgaaacc ttcaaggtgt ctaaagtggg aactatcggt ggatttatgg ttatcaacgg
    11461 taaggttgcc cgtgactcta aagtccgtgt tatccgtgat ggtgtcgtta tctatgatgg
    11521 cgaactcgca agcttgaaac actacaaaga cgacgtgaaa gaagtgacaa acggtcgtga
    11581 aggtggattg atgatcgacg gctacaatga tattaagatg gatgatgtga ttgaggcgta
    11641 tgtcatggaa gaaatcaaga gataagattt tttgctcctt tcttaggtgg tgagggacgc
    11701 aagcaaaccg atggtttcat tgcttatttt tgagcctagg gtctcaaaaa tcccctgtga
    11761 tgggactgat aaatcagttc catcactttc accacggcga aagaagcaga tgacttcaaa
    11821 ttgaacttcg tttcaattta aactgaaaat caagaagttt aaaatagcta ggtctgctgg
    11881 cctagctttt ggttcaaagt agagaaagga atatcatggc aaatcatttc cgtacagatc
    11941 gtgtgggcat ggaaatcaag cgtgaagtca atgagatttt gcaaaagaaa gtccgtgatc
    12001 cacgtgtcca aggtgtgacc atcacagatg ttcagatgct gggtgacttg tctgttgcca
    12061 aggtttatta caccattttg agtaaccttg cttcggataa ccaaaaagcc caaatcgggc
    12121 ttgaaaaagc aactggtacc atcaaacgtg aacttggtcg caatttgaaa ttgtacaaaa
    12181 tcccagattt gaccttcgtc aaagacgagt ccatcgagta tggaaacaag attgacgaga
    12241 tgctacgcaa tctggataag aactaaagaa gaggggttgc ccctcttttt tggtggagga
    12301 aaataggttg aatttgaaat ggaaaaatat tcttttaaaa tatattgaaa ctagaatagt
    12361 ac
//
LOCUS       DAVKBK010000052        12198 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVKBK010000052 DAVKBK010000000
VERSION     DAVKBK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12198
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.052"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(37..384)
                     /locus_tag="VWX69_001593"
     CDS             complement(37..384)
                     /locus_tag="VWX69_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9192909.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKEDYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(495..2270)
                     /gene="spxB"
                     /locus_tag="VWX69_001594"
     CDS             complement(495..2270)
                     /gene="spxB"
                     /locus_tag="VWX69_001594"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU9192910.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2477..4720)
                     /locus_tag="VWX69_001595"
     CDS             complement(2477..4720)
                     /locus_tag="VWX69_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9192911.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4730..5101)
                     /locus_tag="VWX69_001596"
     CDS             complement(4730..5101)
                     /locus_tag="VWX69_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU9192912.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            complement(5112..5507)
                     /locus_tag="VWX69_001597"
     CDS             complement(5112..5507)
                     /locus_tag="VWX69_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU9192913.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5691..5789
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5873..6664
                     /gene="thiD"
                     /locus_tag="VWX69_001598"
     CDS             5873..6664
                     /gene="thiD"
                     /locus_tag="VWX69_001598"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9192914.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(6874..7506)
                     /locus_tag="VWX69_001599"
     CDS             complement(6874..7506)
                     /locus_tag="VWX69_001599"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9192915.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7499..8302)
                     /locus_tag="VWX69_001600"
     CDS             complement(7499..8302)
                     /locus_tag="VWX69_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9192916.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8302..8826)
                     /gene="thiW"
                     /locus_tag="VWX69_001601"
     CDS             complement(8302..8826)
                     /gene="thiW"
                     /locus_tag="VWX69_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU9192917.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(8831..9523)
                     /gene="tenA"
                     /locus_tag="VWX69_001602"
     CDS             complement(8831..9523)
                     /gene="tenA"
                     /locus_tag="VWX69_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU9192918.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9534..10184)
                     /locus_tag="VWX69_001603"
     CDS             complement(9534..10184)
                     /locus_tag="VWX69_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU9192919.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10186..11571)
                     /locus_tag="VWX69_001604"
     CDS             complement(10186..11571)
                     /locus_tag="VWX69_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192920.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11572..12132)
                     /locus_tag="VWX69_001605"
     CDS             complement(11572..12132)
                     /locus_tag="VWX69_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9192921.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
BASE COUNT         3648 a         2738 c         2356 g         3456 t
ORIGIN      
        1 aaaatagcta aggttaacgt caaatgacta cgcgacctat ttcatacgat aaaaatcaag
       61 cactagacca gcaggtcctt gaactaataa ggactctgtt ccccaatcgg ttacagttgg
      121 tccgtgtaaa acctttatac caagctcgtt caaccgtttg tagttctggt ctacatcctc
      181 aacctcgata tgaataatga ttcctgactg aaagttttcc aaaggaacca aatgattttg
      241 tgacaacata aggcagtgac taccaatcgt aaactgagca aaaccatcat cagcataatc
      301 ttccttttta tccaaaatat gctccaagtc agcacagact tggggaacat ttgaaacgat
      361 aatatctaat tgatttaaat tcatttactc tcctccataa aaagaccgga ttgctccgat
      421 cttttaaagt tctgctctat gaaaatcaaa gaataaagtc tacaagtttc atatttgatt
      481 ttcggcgaga ggaattattt aattgcgcgt gattgcaatc cttcttcttc caagaagaga
      541 cggaatggta cgagttcttc tgcttcgtat ttttccttga aggctttgat agcttcttct
      601 gagtgaagtt ttggatccaa ttcaagtact tctactggaa gtggacggtg ttgagtgatg
      661 cgagcatcga tgacaacagt tttaccttct ttgttcaatt taacagcttc tgcaacaact
      721 gcatcgatgt cttcgatacg gtcaactgtg aatccaacag ctccttgagc ttccgcaatt
      781 ttagcgtagt cagcgtttgt gaagtctaca ccaaacaagt gtttgtttgt atcttcgtat
      841 ttgttcttga tgaagccgta ctcagcattt gagaagacaa ggttgataac tggaaggtcg
      901 tattgaacgt ttgtgataac gtctgggtag cacatgttga atgctccgtc acccatgatg
      961 ttccatactt ggcgatctgg attgtctttc ttagcagcga taccaccagg aagggcaata
     1021 cccattgtcg caaagagtgg agatgtacgc cacatgttct taggtgtcat gtgaaggtga
     1081 cgagtagatg tttgagtagt gttacctacg tcgattgagt agatagcgtc ttgatcagca
     1141 tgtttgttga ttgcattgta aacttgatac aattgcaatt caccctcagt tttaccttcg
     1201 agtttgttca tgtaatcacg ccagttttgg ttgttcttaa cgtttgcacg ccaccatgga
     1261 gttgattcaa ctgggtttac tttgtcaagg atagctttag ctgcttgacc agcatcacca
     1321 aggattgaag cgtcaagggc atgacgttta ccaagtttgt aagggtcgat atcaacttgg
     1381 atgaattttt cagtgttctt gaatgcttcg taaacttcag caaatgggaa gtttgaacca
     1441 aggaaaagaa ctgtgtctgc ttcaaagacc acttcgttgg ctggtttcca accaacacga
     1501 taagcagaac ctgtcaaacc ttcatagttc cattcgaaag cttcaaagtt tttaccagtt
     1561 gtgatgattg gtgctttgat tttacgtgac aattcagtaa tcacttcacc agctttaaca
     1621 ccaccaaatc cagcatagat aactgggcgt tcagcattgt tcaagatttc aacagctttg
     1681 tcgatttcaa cttcgttcaa agcaggagcg atgaatgagc gttcgtatga acctgaaccg
     1741 tagtatgagt tttcgtcgat ttcttggaaa ccgaagttta ctggaatttc aacaacagct
     1801 ggaccttttt tagaaactgc agcacggcag gcttcgtcaa ttacttttgg caattgctca
     1861 gcgtaagcta cacgtttgtt gtaaacagcg ataccgttgt acattgggtt ttggttaagc
     1921 tcttggaaag catccatgtt caattcgtta actggacgtg atccaaggat tgctaggaat
     1981 ggagtgttat ccatagctgc atcgtaaaca ccgttaatca agtgagtcgc acctggacca
     2041 cctgaaccaa ctgcaacccc gattgagccg ccgaatttag cttgcataac cgctgcaaga
     2101 gcacctgtct cttcgtggcg aacttgtaag aagcggatat ctttgtcttc agccaaagcg
     2161 tccatcaatg agctgagtgt tcctgatggg ataccgtaga ttgtatctac gccccatgtt
     2221 ttcaatacgt taagcattgc tgcagatgca gtaattttcc cttgagtcat aatgataact
     2281 ctccttcaat ttttttagac ttggagaata cgattacata gaattggaaa cgttctccaa
     2341 ttttttacta ttccactgta tcatatttat gctgactttt ctaaaaatct gctcaaaact
     2401 ctctattctc tattctaata cagttttgaa agtgtcgtca tttctgtttt ataacaaaaa
     2461 aatctagtca ttacttttag tctattttac taaaatttaa cagaagggaa ctggtcagaa
     2521 cagatacaga actaaaggcc atggctagac ctgccaattc tgggttgaga gccagtccaa
     2581 cacctgaaaa gactcctgct gcaatcggaa ttccgacaac attgtagata aaagcccaga
     2641 aaagattgag cagaatacga tgaaaggttt tcttactcat gtcgaaggca cgcaccactc
     2701 ctaaaagatt attggttgtc aacaccaaat ctgctgactc gatggcgata tctgttccag
     2761 ctcccatagc aatccccaca tctgctacac taagggcagg agcgtcattg atcccatcac
     2821 caacaaaggc tactttacct gactgttgca gtttatggat ttcatgggct ttttcttctg
     2881 gcaagacgcc tgcaatgacc tcttcaattc cgatttgatc tgcaatagca cgcgccacac
     2941 cagcattgtc tcctgtcagc atgactgtcc cgagaccacg tttttttagc tgactgatgg
     3001 ctagcttagc atttttctta ggaatatctt gcaaagcaag caagcctttg atttcattgt
     3061 caacagctaa gaacacaact gtcttagctt ctttttctag ttcttctagt ttatcttgat
     3121 aagtattaga aatatccatg ccatccagca ttttagcatt tccaagtaaa acttgttttc
     3181 cattgattcg ccctgaaaca cctttcccgt gcaaggcctg aaaattttca acagtttgaa
     3241 actcaagtcc agcttcactc gctcgcttaa cgatagcctc agccagtggg tgttgagaag
     3301 catcttccaa ggaggctgcc aatccaaaca cttctacttc gtcgccgatg acatctgtta
     3361 ccacaggttt cccttccgtc aaagtcccgg tcttatcaaa gacaagggtt tgaactttct
     3421 ggatttcctg taagacagtt ccatttttga ggagaacccc catcttggca ctacgtcctg
     3481 tccccaccat aagggctgtc ggtgttgcaa gtcccaaggc acaaggacag gcgataatca
     3541 aaaccgccac tccgtagaga agagaggaca caaagctagc tccaagcaca accacactat
     3601 ccctgagcaa gacgaaccaa acccaaaagg tcatgattcc taaaatgaca actactggga
     3661 caaaaatccc tgaaatctta tccgtcaagt cctgaatcgg cgcacgactt gtctgagctt
     3721 tcttcacaaa atccacaatc tgagccaaaa cagtctctga gccaactttt tctgctctaa
     3781 agacaagcgt tccactatga ttgatggttg agccaatgac agtatctcca actgtcttgt
     3841 ccacaggcag actctcacct gtcaccatgg attcgtcaat actagagaca ccttctacta
     3901 cgacaccatc aacagcaatc ttttcaccgg gacgcactcg aatcaggtcg cctaccttga
     3961 cttgttccaa aggaacttgg acataactat catcactcaa gacttctgcg gttttagctt
     4021 gcaagtccag taatttctcc acagcttggg acgtattttt tctcattttt tcctcaaaaa
     4081 ctgctcccaa aagaacgaaa aagaggataa atccagcact ttcgaagtaa acagggagac
     4141 cagcaaagag agcaactagg ctatagaaat aagccactag agttcccagc gcaaccaagg
     4201 tatccatgtt ggcattgtgc tttttaaaac tggcccaagc actctggata tatggcttac
     4261 ctgcaactaa cataataggc gttgttgcta gaaaggttcc ccaatgcatg acttgatgac
     4321 taatgctacc tgccaacatc ccaatcatga gaatcacaag aggcacagta cagatactag
     4381 taatccaaaa acgttgcagg agagatagag attttcgagt cttctcaacg actgtatagc
     4441 ttcccttttg catcttcatg ccacaagaaa attcatgtcg ccctaattct tgaggtgtaa
     4501 aacgaatgac tttctcctca tctacgccga ttggttccaa gataccttct tcttcaaaca
     4561 gaatttcctt ataacagttt gaaggagtag cacgatgaaa ggtaatctca gctggaattc
     4621 ccttttgaag ctggatatgg gctggatgat agcctttttc agcttggata cggatttttt
     4681 gaatgccatt ttctaagctt gctttcacaa tttctgtcat agtctccacc tactctacaa
     4741 tcatcttgcc gtgcatcatg ttcataccac aagcaaagct aaactctcca gcctgttcag
     4801 gcgtgatttc cactacatac tcttccccca ttggcaggtt cgcatgtaca ccaaaatctg
     4861 gaaaaacaat ttgatccaga catggtgaag gatccttgcg gtcaaagaca atgcgggctg
     4921 gcactgattt cttgaggaca atcaactcag gagtatagcc tcccatgact tccactcgaa
     4981 tctcttggta tccgtttttt tgctgggctt tttgtccaga tttttcaggc tttttgaaaa
     5041 accaaaacaa gataaacgcg ataagggcaa tacaaataat ggttacaata ctatttaaca
     5101 tgacgtctcc tttacataca attacatctt acttctgtta cagcacttga tttcttctct
     5161 gaaatcacag cttccaagtc ttccaagtca gtctgagtaa attcacattc tacaatcaag
     5221 tcagccaaca aattcctaat cctacgggaa caaaccttgt ctttgatatc ttggacaagt
     5281 aaatcccgac tttggtctag agttaaaagc gctgaataaa caaaggactt gccttctttt
     5341 ttccgagtca aacactcttt ctcaactaga cgagccaaaa gtgtctgaac cgtggacttg
     5401 gaccagtcaa accgctctgc caaaacccta atcaaatctg tactggtctg ctccccctgc
     5461 atccaaataa tcttcatgac ctgccattct gcatctgaaa tctgcattac catacctcca
     5521 aaatctacat ttgtcaatta cactcaacag tatactccca aaatctacat ttgtcaatta
     5581 tagaaataat attttcttcg aaaaatagaa ttttaatcat ttgaaaaacg atttgcagtc
     5641 aaatattact atataaacaa taaaaatatg ctatactaaa gaaaaaagaa aacaaccact
     5701 aggggtgcgt aaagctgaga ttaacgactg ttagatccct ctgactcaat ctaggtaatg
     5761 ctagctgatg gaagtggaaa tgataatggg gactagcagt cttctattgc ctttctaaaa
     5821 cagactagct tgttcttaag aatacaaact tcagttggtt gggaggtttt agatgactta
     5881 tttacccgtt gctttgacca ttgcagggac tgaccctagt ggtggtgctg gcattatggc
     5941 agatttaaag tcattccaag cgagagatgt ctatggaatg gctgttgtaa ccagtcttgt
     6001 cgctcaaaat accagaggtg ttcagctaat cgagcacgtt tctcctcaaa tgttgaaagc
     6061 ccaattggag agtgtctttt ctgatattcc acctcaggct gtaaaaactg gaatgttggc
     6121 tactactgaa atcatggaaa tcatccaacc ctatcttaaa aaactggatt gtccctatgt
     6181 ccttgatcct gttatggttg ctacaagtgg agatgccttg attgactcaa gtgctagaga
     6241 ctatctcaaa acaaacttac tacctctagc aactattatt acgccaaatc ttcctgaagc
     6301 agaagagatt gttggttttt caatccatga ccccgaagac atgcagcgtg ctggtcgcct
     6361 gattttaaaa gaatttggtc ctcagtctgt ggttatcaaa ggcggacatc tcaaaggtgg
     6421 tgctaaagat ttcctcttta ccaagaatga acaatttgtc tgggaaagcc cacgaattca
     6481 aacctgtcac acccatggta ctggatgtac ctttgctgca gtgattactg ctgaactagc
     6541 caagggcaag agtctttacc aggcagttga taaggccaag gcctttatca caaaagctat
     6601 tcaagatgcc cctcaactcg gtcatggttc tggtccagtc aaccatacaa cttttaaaga
     6661 ttaagaaaaa aaactctcta gttcccactt taagggaatt agagagtttt tatactcttc
     6721 gaaaatctct tcaaactacg tcagcttcca tctgcaactt caaaacactg ttttgagctg
     6781 acttcgtcag tcttatctaa aacctcaagg cagtactttg agcaacctgc gactagcttt
     6841 ctagtttact ctttgatttt cattgagtat taattaggaa agaatgtcat gcaactttgt
     6901 taaaaaggct tgcgtttttg cctcaatatc ttctgcttgc atcaaatcac gtacaacagc
     6961 tacaccagct atgccagtgc ccataagctg atcaatattc tccgaagtca agccaccaat
     7021 agcaactatt ggaatggcaa ccgtttggca aattgttttc aaggttgaaa tcagggtgat
     7081 gggtgcattt tccttggtgg ttgtcggaaa aatggctcct gtccccaagt aatctgcacc
     7141 tgatttctcc gcttccagag ctcttttaac cgttttagcg gtgacaccga ggattttttc
     7201 aggacccaag acttgtcggg caaccgaaac tgggagttcg tcatctccaa tatgcagacc
     7261 agcagcatca accgcaagac aaacatccaa ccgatcatcg attatcaagg gtacctgata
     7321 agcatctgtt atttccttga cttgttttgc cagttgataa tattgattgg ttgtgagatt
     7381 tttttctcgc aattggacta tggtaacccc tgaacggcag gccgtctcaa cttttgcaag
     7441 aaagctttcc acggaatctt gatagcgatt ggttaccaga tatagtctaa gtgcttctct
     7501 attcataaac ctctcctttg atggtatcta gccaattttc atctcttctt aggagcgaaa
     7561 gctgattgag tacttggtaa cgaaattctt ccaatcccat tccttgaaca actattttct
     7621 cagcagcgat attgagataa gagactgcta agcaagaagc ttcaaaacca gtctttcctt
     7681 ggctgagaaa aacggctgtt aaggctccaa ccaaatctcc tgtccctgtt atccagtcta
     7741 attctgcaca gccatttccc agtacagcga cctgattttt cgaaacgacg aggtccttgg
     7801 gacctgtgac taagaaagac ataccatgat aggtctgaca ccagtctttc aagacttgaa
     7861 gcaaatcctc cgtttcttga tctttagcac tcgcatcgac cccaacgccg tggtgcttta
     7921 atccaacaag acttcgaatt tctgacatgt ttcctttaag gaccgtaggt ctatagtcta
     7981 aaaggtctct gactaagctc ttacgaatgg atgaagctgt tacgccaacc gcatctacta
     8041 ccattgggag acaaacttga gctgcataag aagctgctat acggattgct ttctccttct
     8101 cagctgacaa atgccccaaa ttgatgaaga gagcctgact ttgcttagta aaatcaagaa
     8161 cctcacgggg atcatctgcc atgacaggtt tgcatcccag agccaaaatc ccatttgcca
     8221 gcatctcaca agaaatctca ttggtcatac agtgaatgag ggaactagag cctataggaa
     8281 agggatttgt aaattcctgc atcagtctat cctttcacta aagaaatatc cctgcacttt
     8341 tttaaagaat tcctgcttga ttaaaaatcg aaaggcaata aaggaaatcg ctgtaccaat
     8401 caaggttgct ccgaaaaatc gaggcgtgta gataaaccag ctaagcttag cagctgatcc
     8461 tgtaaagagt accataacag gataggaaac aatagaacca ataatacctg ttcccacaat
     8521 ttctcccaag gcagaaaagt aaaattttcg accgtactta taaaagagac ctgctagaag
     8581 ggctccaaaa gtcgctcctg tgagagctaa aggcggaatc ccttgagtcg tcatacggat
     8641 aaaggctgtc actgtagcca tagccaaggc ataaacaggt cccatcatga ttcccgctag
     8701 aatattgact acactggaca tcggtgccat tccctcaatc cgaaagatag gtgtaaggac
     8761 tacatcaagg gcaatcatca tagataaaat ggtcaatttg tgaacttgta gttggtgctt
     8821 tctcatgttt ctattcttct cctttttcta aagactgtaa atcgctcttc catgtctggt
     8881 gttggtaagc catctcccaa aacttggctt ccatatgaac actgatgtgg aaggcatcta
     8941 gcattttttg cttatctgtc tcatcacttt ctcgatagag ctgattgacc agtgctccct
     9001 cctctctgat ctgttgctct aactcatccg taatataagt ttcaatccat tgttgataga
     9061 gaggatttgg tgatggttta agattaagtg atttgcctat atcatggtat aaccaaggac
     9121 aaggaagcaa gcttgcaaaa gcgatggcta agttcggttc tgcaaattgc ctataaatat
     9181 gagaaatgta atgataacag gttggagcga ttggatgttg ctccatttcc tggtcgctga
     9241 tttccaattc cttgaaaaat tgttggcgaa taaataactc accctccact aaaccctgag
     9301 cattttgttt caagagtctt ttcatctctt ggtttgaagt cttatcagcc aaaagatgat
     9361 agatttctga gaaagccttc agatagtagg catcctgaat caggtaatag cggaaaatgg
     9421 caggttctaa attcccctct tgtaattgta aaataaaggg atgatgaaag gaagcctgcc
     9481 aagctttctt ggataattcc atcgcaatat ctgtaaattc cataataact cctttataaa
     9541 aatagactgg tttgaagcaa taaaaagaaa agcaggtaga ttaattttgt ttttttagga
     9601 atataaaaag tccgatagct attcttcaac tgtgcatgtt cgtcatatcc gtgagcagat
     9661 agagctctca ggtaaagatg gcgccaccta aagactgtca tcagaacctt actgtaaatc
     9721 aagggcgacc aaaaatgtag ttcttgacca cgtaataggc aagcttcttt gagggacttg
     9781 atttcttgct gaatgagagg aaaagaattg aataccacaa tcaaggcata ggaccaagag
     9841 cgtgatagcc ccttttgagc caagtacaag agaagctctt ttagtgaaat agaggaaaca
     9901 aagacaaggc cgatacaaac tgtcacaaag gccctcgttc caagcatgac tgcctgtgaa
     9961 gcatctccgt gtaactgaac tgcccagtag ttggcaaaag atggtaaaat ggcaagtatg
    10021 atcatccaag ctaacatttt aaatcgacgg taatagagca taaagagaat acaaaatgcg
    10081 actaccgaaa gattcagagc aatcgaagga atgaaagatg tttccaagga taaaatcagc
    10141 aagaagagac tgataatcgg tgtctgggtt gctactttga ccatactatc tcacctcccc
    10201 ttgggtattg ctactctgag atgtaagtgg tttggtaatg gtcacttctt tcacatgccg
    10261 aagaccctga ctagtcatct caatccaata atcaaccaca gaaatcaaag ggtctaaacg
    10321 atgactaatg agcagaaaac ttcttccttg attcctctcc tccacaatcc acttgcaaaa
    10381 ataatggcag gctctatcat ccaaacctgc aaaaggttca tctagcaaga tcacggaagc
    10441 cttactggtc aagatggtca ggagctgaag aattttttgc tgaccaccac ttaattgata
    10501 gggactctta tcgactgcct gctccaaatc aaaatatcgt aaagcttgaa aaatccgctg
    10561 atttctttca gaatcaggtc catctaattg aagctcctct cgcagactga ctcggataaa
    10621 ctgcttctca gcttcctgaa caacaccagt cagatcacga tacaaactct ttttcttttt
    10681 caggaccgaa cccttccatg caatgcgccc cttatacttt tgaaattgaa gaatagaccg
    10741 aaagagggtt gatttcccga caccattgtc acccaggata caggaaatcc cttgatagaa
    10801 tgtgaaatca gcaattgaaa agagggggcg atttccaaac tcacaagtcg ttctatccat
    10861 atggaatagt tccgggctag aagcaacttc ctttgaagca acctgtgtca tctcatagga
    10921 agggatttga aacacttccc ttagttttcc gtctcttagc tcaaccatat ggtcgatata
    10981 ggctttatag tcagataaat catggtcgca caaaataact gtctttccat caagagccaa
    11041 ctcttttaga atctccaata tctcgattct gctcttgcgg tcaatggaag caaaaggttc
    11101 atccaagaga tagaccctag gattcatggc aaagaggaca gccagcgctg ctttttgctt
    11161 ttccccacct gataggtgat gaatgggacg gtgtaagatt gcctcgcaac gacattgctg
    11221 gacaacctct gctattttag aatcaatttc ctgaaggtga tagccgatat tctccaaggt
    11281 gaaaatcagc tcctcaaaca agctctccat ggtaaattga tgattgggat tttgaaagag
    11341 aatgccaacc ttctggacac gtgcgatgat agaaagttga ctgacctcgc tcccatctat
    11401 caggacttga ccactatagg gaagagaact gacttgggca atcatttgaa agaggctgga
    11461 ttttccagac ccactactcc caactaacaa ggtaaaggct tgcgcatgaa aagtaaaatc
    11521 aaacggctca gagaagattg gggactgaat cgctcgtagt tccagaccca tctatgcttt
    11581 tcctccagtt gcaaactgat gatagagttt gacaatggca cgaaccaaga tggtacagaa
    11641 gaaataaaca gaaataaaac gtaccacaag taaggaaagg acaaacggaa gggaaaaggc
    11701 gtagtaacct aacttaatgt attcatagac aaagctaaca agcgtaatcc caatactatt
    11761 agcagttaga gagagccaac tttcatagcg attcttagtt acgataaaac caaattcact
    11821 tcccaaacct tgaaccaagc cagacaaaag agctcctaga ccaaattggc taccataaag
    11881 gacttcagca agcgcagcta gcacttctcc aatcgttgca cttccgactc tcggaacaaa
    11941 gatggcagca atgggcgcag ccatacacca gagaccgaag aggatttcat tggcaaaggc
    12001 ctgcaaacca agaggtgtta agagtagact gagaatatta tacacatatc ctgaaccaac
    12061 gaaaacccca ccaaaaaaga tagacaagaa agcaagcaag ataacatctt ttaactgcca
    12121 ttttttcaac ataaaaaact ccttttttta aagaaaagtg gggcactcaa gaagaccgac
    12181 ctaaatactt tgtatagc
//
LOCUS       DAVKBK010000053        11812 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVKBK010000053 DAVKBK010000000
VERSION     DAVKBK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11812
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.053"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            112..765
                     /locus_tag="VWX69_001606"
     CDS             112..765
                     /locus_tag="VWX69_001606"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU9192922.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            775..1239
                     /locus_tag="VWX69_001607"
     CDS             775..1239
                     /locus_tag="VWX69_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9192923.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1252..2520
                     /locus_tag="VWX69_001608"
     CDS             1252..2520
                     /locus_tag="VWX69_001608"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU9192924.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKFNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2534..2794
                     /locus_tag="VWX69_001609"
     CDS             2534..2794
                     /locus_tag="VWX69_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192925.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2805..4166
                     /gene="pdrM"
                     /locus_tag="VWX69_001610"
     CDS             2805..4166
                     /gene="pdrM"
                     /locus_tag="VWX69_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU9192926.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            4320..5288
                     /locus_tag="VWX69_001611"
     CDS             4320..5288
                     /locus_tag="VWX69_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU9192927.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5304..6296
                     /locus_tag="VWX69_001612"
     CDS             5304..6296
                     /locus_tag="VWX69_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU9192928.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNSVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6514..7557
                     /locus_tag="VWX69_001613"
     CDS             6514..7557
                     /locus_tag="VWX69_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU9192929.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7621..9306
                     /gene="lpdA"
                     /locus_tag="VWX69_001614"
     CDS             7621..9306
                     /gene="lpdA"
                     /locus_tag="VWX69_001614"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU9192930.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9370..10359
                     /locus_tag="VWX69_001615"
     CDS             9370..10359
                     /locus_tag="VWX69_001615"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU9192931.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10432..11502)
                     /gene="xerS"
                     /locus_tag="VWX69_001616"
     CDS             complement(10432..11502)
                     /gene="xerS"
                     /locus_tag="VWX69_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU9192932.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3508 a         2206 c         2657 g         3441 t
ORIGIN      
        1 attcaaatcg tatatatagt cgatttatta aatctttaga taaactgtaa aaagtggttt
       61 ccatagccac tttttgctat aatagaggca gtaaaaatga aggagtcggc tatggaacac
      121 tcgtcttggc atgctttgat taaggcgcaa ttacctgagg gttatttcgg gaaaatcaat
      181 cagtttatgg agcaggtcta ttctcagggg attatttatc cacccaagga aaaggttttt
      241 caggctctct tgacaacact gcttgaagaa gttaaggtgg taattctagg gcaagacccc
      301 tatcacggac caggtcaagc gcagggcttg agtttttctg tacctgactc tatcccagct
      361 ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg atatcggagt taagaaatct
      421 catgatttga cagcttgggc tgagcaagga gtcttgcttc ttaatgcttg tttgactgtt
      481 cctgctggac aggccaatgg tcatgctggt caaatctggg agccttttac tgatgctgtg
      541 attcaggtgg tcaatcatct agatagacca gtcgtttttg tactctgggg agcttatgca
      601 cgtaagaaga aggcattagt taccaatcct catcacttga ttatcgaatc agcccatcca
      661 agtcctttgt cggtttatag aggattttgg ggttccaagc ccttttccaa ggccaatgca
      721 ttcttaaaag agacaggaca agagccaatc gattggctta gataaggaga aaatatgcct
      781 cagttagcga cgatttgcta cattgataat gggaaagaac tgctcatgct ccatcgtaat
      841 aagaaaccca atgatgtcca tgaagggaaa tggattggtg tgggtggtaa gctagagaga
      901 ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg aagaaacagg gctcaaagcc
      961 aagccagttc taaaaggtgt catcactttt cctgaattta caccagattt agactggtac
     1021 acctatgttt ttaaggtgac ggagtttgag ggcgacttga ttgactgcaa tgaggggacg
     1081 ctagaatggg ttccctatga tgaggttttg agcaagccga cttgggaagg tgaccacacc
     1141 tttgttgagt ggcttttaga ggataaaccc ttcttttcag ccaagtttgt ttatgatggg
     1201 gataaattgt tggataccca agttgatttc tatgaataaa ggagaaagca gatgctacta
     1261 atcaaaaatg gtcgtgtaat ggatcccaag tctggtttgg atcaagtttg tgatgtctta
     1321 gttcaagatg ggaaaattat caaaattgcg cctgagatca cggaagaagg agcagaaacg
     1381 attgatgcta ctggtcttgt ggttgctcct ggtttggtcg atattcatgt gcatttccgt
     1441 gaacctggtc aaacacataa agaagacatt catactggtg ccctggcagc cgctgcaggt
     1501 ggttttacta ctgtcgtcat gatggctaat accagtccaa ccatttcaga cgtggagact
     1561 ttgcaagcag ttctccagtc agctgccaaa gagaagatta atgtcaagac agttgcgacc
     1621 attactaaaa actttaatgg taaaaacttg actgacttta aggcgctctt agaagctggt
     1681 gcggctggtt tctctgatga cggtattccg cttgagagca gtaagattgt caaggaagcc
     1741 atggaggaag ccaaaaaatt caataccttt atcagccttc atgaggaaga tccaggtttg
     1801 aacggtgttc ttggctttaa tgaaaatatt gctagagaac atttccatat ctgcggtgct
     1861 actggagtgg ctgagtacgc tatgatggcg cgtgatgtca tgattgccta tgcaactaaa
     1921 gcccatgttc acatccagca tttgtctaag gaagaaagtg ttaaagtagt ggagtttgct
     1981 caggggttag gtgcagaagt cacagcagaa gtagcgccac agcatttctc taagacagaa
     2041 gcacttcttt taacacaagg tagcaatgct aagatgaatc caccgcttcg tttggaatca
     2101 gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca tcacagttat tgcgactgac
     2161 cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata ttaccaaagc gccatctggt
     2221 atgactggct tagaaacatc cctgtctctc agcttgacct atttagtaga agctggtgag
     2281 ttgagcttga tggaattact tgaaaaaatg acatacaacc cagccaagct ttacaacttt
     2341 gaagcaggtt acttggctga gaatggtcca gcagatatca ctatttttga tgccaaggct
     2401 gaccgctttg tggactccca ttttgcttcc aaagcagcta attcaccatt catcggtgaa
     2461 accttaaaag ggcaggttaa atataccatc tgtaagggac aaatcgtcta tcaagcttga
     2521 taggagttag aatatgaatt attttcgaaa acgtagggag agacaagcga aatctaatag
     2581 tggaatttac tgtcccgcag ctaatcgttc caaaattcaa tatgaaacta aagaaaaagc
     2641 tgaccatgcg gttcaatatg ataacggagg tttagttaga agctattatt gtcgtacatg
     2701 tgcgtgttgg catactactt caaaatctaa taaacctccg ctaagtttga aaaactatgg
     2761 tctgaaactc tttggtttag ataaatcaga atagaaagag aagtatgtat aagacaaagt
     2821 gtttacgaga gaagttagta ttatttttaa aaattttctt cccaatcctg atctaccaat
     2881 ttgccaatta ttctgcctct tttgttgata ctgcaatgac aggtcaatac aacactatgg
     2941 acttggctgg tgtatctatg gcaaccagta tctggaatcc tttctttaca tttctaacag
     3001 ggattgtgtc agccttggtg cctatcattg gtcaccatct tggtcgaggc aaaaaggaag
     3061 aagttgcgtc tgatttttac caatttattt atttggcctt gggcctatct gtggtcttgc
     3121 tggggatggt acttttcttg gcaccaataa tcttgaatca tattgggtta gaagcagcag
     3181 tagcggcagt agcggttcgc tatctttggt ttttatctat cgggattatc cccttgttgc
     3241 tctttagcgt cattcgttcc ttgctggatt cgctgggctt gaccaaactg tccatgtacc
     3301 tcatgctttt gttactccct ctcaatagcg gatttaacta tctcttgatt tacggtgcct
     3361 ttggtgttcc agaactggga ggggctggtg ctggtttagg aacatccttg gcctactggg
     3421 tcttgcttgg gatttctgtt ctggttttat ttaaacagga gaagctcaaa gccttacacc
     3481 ttgagaaacg aattccactt aatatggata acattaagga aggagttcgt ttaggtctgc
     3541 ctattggggg aactgtcttc gcggaagtgg ctatcttttc agtggttggc ttgattatgg
     3601 ctaagttttc gtccttgatt atagctagtc accagtcagc tatgaacttt tcaagtctta
     3661 tgtacgcctt tcctatgagt atctcatcgg ctatggctat tgtcgtttcc tatgaagtgg
     3721 gagccaagcg atttgatgat gcgaaaacct atattggtct aggaagatgg actgctctca
     3781 tttttgcggc cttcacctta accttccttt acatttttag gggaaatgtg gccagtcttt
     3841 atggtaacga cccaaaattt atcgatttga cagtgcgttt tttaacttat agtcttttct
     3901 tccagttagc agataccttt gcggcgccgc ttcagggaat tttgcggggg tataaggata
     3961 cagttattcc tttttacctt ggtttgcttg gttattgggg cgtagcaatc cctgtggcta
     4021 cgctatttga ttccctaaca gattttggag cttattctta ctggatcggc ttgattatta
     4081 gtttgattgt gagcggggcg ctctaccgtt ggcgtttaac tgtgattatg aagagatttg
     4141 aatctttagc aaaatccaaa tgctaaaaag tttgtgaaaa aatattcttg acaagaaaat
     4201 cccttgtttt cacggggttt tcttttttat tttgtgaaat ttcttttaga aaaactttga
     4261 cagtatttgc caaaagcggt aaaatagtaa ggtaagaaga aagttagaaa ggcaagaaga
     4321 tgtcaacttt agataaaaat cttttgctag aaatgttccg taagatggaa gaaatccgtc
     4381 gcatggactt aaaaattgca caattagtaa agaaagggaa agtgccagga atgacgcact
     4441 tttctgttgg tgaagaggca gctaacgtgg gggctatgtt agctctcaat ccagatgatc
     4501 tgattacctc aaaccaccgt ggacacgggc aagctattgc taaagggatt gacctcaacg
     4561 gaatgatggc tgaaatcctt ggtaaataca ctggaacctg taaagggaaa ggtggatcta
     4621 tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa tggtatcgta ggtggtggta
     4681 tggggatcgc tgtcggtgca gccctcagtc agcaaatgca aaataccggt aaaatcgttg
     4741 tctgcttctt tggagatggt gcgaccaatg aaggtgtttt ccacgaagca gtgaacatgg
     4801 cttctatctg gaacctgcca gtcattttct attgcattaa caacggttac ggtatctctg
     4861 cggatatcaa gaaaatgacc aatatagaac atatccatca acgtagcgcc gcttatggaa
     4921 ttcctggaat gttcatcgaa gacggtaaca atgtcatcga tgtctatgaa ggatttcaga
     4981 aagctgtgga ccatgttcgc agtggcaatg gtccagtctt gattgaaagt gtaacttatc
     5041 gctggctcgg tcactcatca tctgaccctg gtaaatatcg tacgcgtgaa gaagtggaat
     5101 tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta ccttattgaa aataacattg
     5161 caagtgccga agaattggaa gaaatccaag cgcaagtaaa ggaagcagta gaagcttctg
     5221 ttaaatttgc agaggaaagc ccattcccac cgcttgaatc agcctttgaa gatatttacg
     5281 cagactaagg agaaagagat aaaatggaaa caaaaacaat gtccttccgt gacaccatta
     5341 tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt gttcttgatg ggagaagacg
     5401 tcggtgtctt cggaggagac ttcggtactt ctgttggaat gcttgaagaa tttggtccag
     5461 aacgtgtccg tgactgtccg atttctgaag ctgccatctc tggagcagca gcaggagcag
     5521 ccatgacagg acttcgtcca atcgtcgata tgaccttcat ggacttctct gttattgcca
     5581 tggacaatat cgtcaaccaa gctgctaaaa cacgttacat gtttggtggt aaaggtcagg
     5641 ttccaatgac tgttcgttgt gcagctggta acggagttgg ctctgccgcc cagcactcac
     5701 aatctctaga gtcttggttt actcacattc caggacttaa ggttgtggca cctggaacac
     5761 ctgcggacat gaaaggcctg cttaagtctt ctatccgtga taacaactca gttattatac
     5821 ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc agttgatcca gactacacaa
     5881 ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga tgtaacagtt gttacttatg
     5941 gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt agcagaagaa ggaatttcag
     6001 ttgaaattgt tgacccacgt acccttgttc cgcttgataa ggatatcatc ataaactcag
     6061 tgaagaaaac tggtaaggtt gttctggtca acgatgccca caaaacaagc ggctatatcg
     6121 gtgaaatttc agctattatt tcagaatcag aagcatttga ctatctagat gcaccaatcc
     6181 gccgttgtgc aggagaagat gtgccgatgc cttatgcaca aaacctagaa aatgcaatga
     6241 ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac ttataacaaa gaatagggtt
     6301 acataagata agttatgtaa ataaaataaa gctgacgaga aactttgtat cttttaggtg
     6361 cagagctctt cgtcattaat atcttagatt agagcacggg ctaaaagatc ggaaaaaaga
     6421 taaatctcct tggcttcatc gaagccatcg tcgatttcct atttttcagt cgcttttgac
     6481 gccctttgta tcataaatag aattggagag gtcatggctg atgacaagct aagagcgact
     6541 cctgcagcta gaaagttagc ggatgattta gggataaacc tctacgacgt ttctggctca
     6601 ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt ataaagacac aaacgtggtt
     6661 cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata acattgcttg gcaggaaatc
     6721 caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg ttttggccct gcttcctgaa
     6781 aatatcgaaa acgatagcat caaatctcct gctcagattg aaaaagtgga agaagtccct
     6841 gataacgtaa caccatatgg taaaatcgag cgtattccaa tgacaccaat gcgtaaggtt
     6901 attgcccaac gcatggttga atcttacttg actgcgccaa ccttcaccct caactatgaa
     6961 gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc ttgagccaat catggaagca
     7021 actgggaaga agactactgt aacagacctt ctttcgcttg cagttgttaa gactcttatg
     7081 aaacacccat acatcaacgc ttcattgaca gaagatggca agactattat cactcacaac
     7141 tatgtcaatc ttgccatggc agttgggatg gataatggat tgatgacacc tgttgtttac
     7201 aatgctgaga agatgagtct ttcagaactg gttgtagcct ttaaggatgt tattggccgt
     7261 accttggatg gtaaattggc tccaagtgag ttacaaaatt caacattcac aatcagtaat
     7321 ttgggaatgt ttggtgttca gtcctttggt ccgattatta accaacccaa ctcagctatc
     7381 cttggtgtca gttcgacaat cgagaagcca gttgtcgtca atggtgaaat tgtgattcgc
     7441 ccaatcatga gtttaggatt aaccattgac caccgtgtcg tagatggtat ggctggtgct
     7501 aagtttatga aggacttgaa agagttgatt gaaacgccaa tctcaatgtt aatttaagag
     7561 caagagtatt catttttaag atatagataa aggaaggaag acatggcctt agaagtaatt
     7621 atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg tccaatggaa taaaaaagtc
     7681 ggagaatttg taaaagaagg agaaatcctt ttggaaatca tgactgataa agtcagcatg
     7741 gaattggaag ccgaagaaga tgggtacttg attgccattc tcaaaggaga tggtgaaact
     7801 gtccctgtaa cggaagttat cggttacctt ggtgaagaaa gggaaaacat cccaacagct
     7861 ggagcagcat cgccagaagc tagctctgta cctgtagcaa gtacctcaaa cgatgatgat
     7921 aagagcgatg atgcttttga tatcgttgtg attggtggag gtcctgctgg ttatgttgca
     7981 gccattaaag ctgcccaatt cggcggtaag gttgcccttg ttgagaaatc tgaacttggt
     8041 ggaacctgct taaaccgtgg atgtattcca accaagacct accttcataa cgctgaaatt
     8101 attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga ttgaaaatcc taacttcact
     8161 gttgatatgg aaaaactttt agaaactaaa tctaaagttg ttaatactct tgttggtggt
     8221 gttgcaggac ttcttcgtag ctacggagtt actgttcata aaggaattgg tacaatcact
     8281 aaagacaaga acgtcttggt aaatggttct gaattgcttg aaaccaagaa aatcattctt
     8341 gctggtggtt caaaagtcag caagatcaac gtccctggta tggaatctcc acttgtcatg
     8401 actagtgatg acattcttga aatgaacgaa gtgccagaaa gccttgttat catcggtggt
     8461 ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat ttggttcaaa agtgactgtt
     8521 atcgaaatga tggaccgtat agttccagct atggatgtgg aagtttctaa gaaccttcgc
     8581 ttgattcttg agcgtaaagg aatgaccatc ttgactggta ctaaactgca agaaatcatt
     8641 gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag acgatatcat cgcaagcaaa
     8701 gctcttcttt caattggtcg tatgccagac cttgaaggta ttggagaggt tgagtttgaa
     8761 ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa cttcagttcc aggcatttat
     8821 gcaccaggtg acatcaacgg tactaagatg ttggctcacg cagctttccg catgggtgaa
     8881 gtttccgctg aaaatgccct taaaggaaat catgcagttg ccaaattgaa tttgactcct
     8941 gcagccatct acactctccc tgaagtagca gcagtaggtt tgacagaaga acaagcccgt
     9001 gagaaatacg atgttgccat cggtaagttt aactttgctg ctaacggtcg tgctattgca
     9061 tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata agaaatacgg agaaatcctt
     9121 ggtgtacaca ttattggtcc tgcagccgca gaattaataa acgaagcatc aagcatcatc
     9181 gaaatggaaa tcactgttga ggaaatgctg aagaccatcc acgggcaccc aacttactct
     9241 gaagtgatgt acgaagcgtt tgcagatgtt ctaggaatgg ccatccattc acctaagaaa
     9301 aaataaaacg aagatagatt agactggaag gttatttcca gtttctatca tataaagtaa
     9361 agggatatca tgaaatacat tatcaatcat tcaaatgaca ctgcttttaa tattgccttg
     9421 gaagaatacg cctttaaaca ccttttggat gaggatcaaa tcttcctact ttggattaac
     9481 aagccatcta tcattgttgg tcgtcaccag aacactatcg aagaaatcaa ccgtgattat
     9541 gttcgcgaaa atggtattga ggtagttcgc cgtattagtg gtggtggagc tgtttaccac
     9601 gatttaaata acctcaacta cacgatcatc tccaaagaag atgaaaataa ggcatttgac
     9661 ttcaagagct tctcaactcc ggttatcaat accctggctc aacttggggt taaagctgag
     9721 ttcacaggtc gtaatgacct tgagattgat ggtaagaagt tctgtggcaa tgcccaagcc
     9781 tatatcaacg gccgtatcat gcaccacggt tgcttgctct ttgacgttga tttgtcagtc
     9841 ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat caaaaggtgt gaaatccgtc
     9901 cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa aaatcacagt cgaaaaattc
     9961 cgtgatttac tcttggaata catgaaaaaa gagtacccag agatgactga atacgtcttt
    10021 tcagaagaag aattggccga aatcaatcgc atcaaggata ctaagtttgg aacttgggac
    10081 tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg gaatcaaatt cactagtggt
    10141 aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc aagacatcaa gatttatggt
    10201 gacttctttg gtattgaaga cgttgctgca gtagaagatg tccttcgtgg ggtgaaatac
    10261 gaacgcgaag atgttcttaa ggcgctaaaa accattgata tcacacgcta cttcgctggt
    10321 attagccgtg aagaaatcgc tgaagcggta gttggataaa tcaaaaagaa gttggccaac
    10381 taaccaactt ctttttttga tatttattta cataatttaa aatacgtaaa atcataaact
    10441 atccagagca ttcttttgtt catcattaac aatatgggta tagaggtcag tgacttgtgt
    10501 gctggcatgt cctagttggt gactgactaa aacttgtgat ttagtagcat catagagcct
    10561 agttgctagt gtatggcgca gtttatgggg tgttacacgt actttaaaat cctctgagta
    10621 tttagcaacc attttctcaa cgctagaagc atcgatacga ttaggaacac ctctgtagag
    10681 agttaaaaaa agggctgtat ctgttttttc cgttttatag cgttgattcc gaatggccag
    10741 ataattctct aaataaggtt tagcaaaagc agcgacattg actgagtcac gtttgccacc
    10801 ttttcgagta acatcaataa ccatcatttt tagattgaga tctcttagat ctagattaac
    10861 agcttcagat aagcgaacac cagatgccaa gagaagggca ataatggcta aatctcgttc
    10921 tttatttttg ttgaatgatg agagagctcg atttgaaagc tgttgtgggt gctcttgatc
    10981 gatataagtt agaaaacctt ctgtttcatc acctagaaag agtttttgct tgatattttc
    11041 agctctggca gcaagggttt ctttcttttt cttggttgaa acttttttca ttacattacg
    11101 atagaaataa ggttccccct gatcgttttc aacctcctcg gttagatact tgtaaagact
    11161 agaaagtgct gataaggttc gattgatagt tgtctgtgaa acaccttgtt ttgttgtatt
    11221 agcattcagc aagggacgtt cacgtagata aaggataaag gattccatgt ctttcttaga
    11281 catattttcc aaaactgata aaggaatatc ggatatttta tcagcgtttg aaataccaga
    11341 ctccaaaacc cagctgaaaa atcggtcata ttccttaagg tattcgtaca gggttgtaaa
    11401 actgtagggc acagccagtt tagattggta gtattccaga acataccagg gcatgagttg
    11461 ttttagtttg tcgattcgtt ccagtaaaat ctcacgtttc atgtattttc tccataatta
    11521 agtatactag tagtatagca tagacttgta tatttttcaa gaaaattata gtttttcaga
    11581 aagatgctat aggagttttt caaagtgata aaaagactta gacctacaaa caaaacagaa
    11641 taaggaaaat aataaaaatc tcacccacta aacttctgtt aatactacat aactgaagag
    11701 ctatataagg agctatgaga tacaaaacac attgtataat agattgaaac tagaatagta
    11761 catctggact tctaaaacat tgctagaaat tgatttgatt gtcctgattg tt
//
LOCUS       DAVKBK010000054        11733 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVKBK010000054 DAVKBK010000000
VERSION     DAVKBK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.054"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(342..1235)
                     /locus_tag="VWX69_001617"
     CDS             complement(342..1235)
                     /locus_tag="VWX69_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9192933.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(1986..2216)
                     /gene="blpU"
                     /locus_tag="VWX69_001618"
     CDS             complement(1986..2216)
                     /gene="blpU"
                     /locus_tag="VWX69_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU9192934.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(2419..2709)
                     /locus_tag="VWX69_001619"
                     /pseudo
     CDS             complement(2419..2709)
                     /locus_tag="VWX69_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2755..2988)
                     /locus_tag="VWX69_001620"
     CDS             complement(2755..2988)
                     /locus_tag="VWX69_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9192935.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(2994..3986)
                     /gene="plsX"
                     /locus_tag="VWX69_001621"
     CDS             complement(2994..3986)
                     /gene="plsX"
                     /locus_tag="VWX69_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU9192936.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(3983..4753)
                     /gene="recO"
                     /locus_tag="VWX69_001622"
     CDS             complement(3983..4753)
                     /gene="recO"
                     /locus_tag="VWX69_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU9192937.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(4750..5919)
                     /locus_tag="VWX69_001623"
     CDS             complement(4750..5919)
                     /locus_tag="VWX69_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9192938.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            6068..7078
                     /locus_tag="VWX69_001624"
     CDS             6068..7078
                     /locus_tag="VWX69_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HEU9192939.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(7361..7798)
                     /locus_tag="VWX69_001625"
     CDS             complement(7361..7798)
                     /locus_tag="VWX69_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU9192940.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(7883..10516)
                     /gene="polA"
                     /locus_tag="VWX69_001626"
     CDS             complement(7883..10516)
                     /gene="polA"
                     /locus_tag="VWX69_001626"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU9192941.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPDIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            10772..11122
                     /locus_tag="VWX69_001627"
     CDS             10772..11122
                     /locus_tag="VWX69_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9192942.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            11337..11453
                     /locus_tag="VWX69_001628"
                     /pseudo
     CDS             11337..11453
                     /locus_tag="VWX69_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            11446..11679
                     /locus_tag="VWX69_001629"
     CDS             11446..11679
                     /locus_tag="VWX69_001629"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192943.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         3404 a         2800 c         2015 g         3514 t
ORIGIN      
        1 tttaactttt atacgattac tacctccttt ttagtttaca cttcctacat cataaataaa
       61 catactcaac cctcacaatc tccaaataac tcttctatat cattgaaaat tgagtttcat
      121 cctctatact aatgtaggaa acctattaaa acattccttt aatccaatat aagaatacct
      181 tgttccatta atctctaccc gatattatag atagaaccag actcctatac ttaaaaggac
      241 aaataacgtt ccaaccataa taaacctcct ttctttttga gaacgttttc tttataggtt
      301 tagtatagca aaaacatgaa aaaaacaacc tgacttagaa gtcaggttgt tgggaaatct
      361 atctgttttt ctgctaaaat tctctgaact aatacctgat cgtctagcaa ttctgctaga
      421 gaaatcgcct tttcatagaa actttctgcc tctaaaatat tcttgtctac aaataaagca
      481 tattttgcct ttagcaaaaa tagatgaggt cggtaaaaaa catgtcttgt tttagcaata
      541 attttctcaa atgtttgaat atatatcaga ctatcttctg tctgaatttg gataaatagg
      601 ctcagaagaa ctttttccat ttgaactagg ctagccttat cttcatattc tgaacatagc
      661 aatacttttt gagctaactc ctcaaaatgt tctttatctt ctaatcccat agcacaacaa
      721 aagaaataca attcaataat caacaaatca tttacagaaa aatatttctt ttttaataac
      781 tgctggaaat attcttccac taaccctaaa ccgtaggtca catctgaact accataaata
      841 tcaaaacgag cttgtgtcac atccacaatt aactgctctt cctcaggcaa attctcataa
      901 tagttttcat atatttcctc aagtatagct tcttttcgtt cgattcttcc cttatcagcg
      961 taggtttgag aatgaatcag ctcatctttg agttttagga atccttttgg aatctctata
     1021 accttaacat ccacaatatt ctgtaatgat actccaagtt tatccgcaat caataataat
     1081 ttaggaagtg ttgctaaagc ttgcccattt tcaatacgtg ctagctgacg aatcgtcaac
     1141 tctgattcat caccacaaat atctatctga gtttttccac aagatcgcct aatagttttg
     1201 attttataac caatttcacg tttcaactca tccatagtaa tactccttaa gttgattaca
     1261 aagatttctt tttcttccta attcttttgt caatcatata taaaacgata agcgaaaaca
     1321 gcggtagaac aatataactc ttttcactca ttatcagctg aaatcccagg gttgctagta
     1381 tcttaaagat gaaaatattc atcaaaaata gaaaaacaaa tactaaaaaa tattttaaaa
     1441 ccttcttcat ttcttttctt caactttcct aatttctaca cctattttat cgaaaatata
     1501 tataaaactc caaataaaca cttcgactgc actttttttg gcaaaaaata gacagaacaa
     1561 acatcctatc tactaaaaat atgatatgaa aggaaattga ttttttactg tcaccctagg
     1621 caagcttgaa acaaataaat cattgatagt aacacttacg acatcctatt tattacttca
     1681 atttctaatg tctctgctat ttctaagcta cctctggtat gatctattcc tagtcagaat
     1741 agataacacc gttctaaatt acgattcata gttactcctt ttttgactcg ttactataag
     1801 actcctcttt acatgcgcaa aataattttg attcagattc atcatttata gttttgatta
     1861 ttttttaaca gatttttctg ttttcttctc cgaagacttt aaaaattttt ttctaattaa
     1921 atcatccata taaggaccaa atataccaac tactaaacca ataataaaac ttttaaaatc
     1981 cataattacc accaacatgt cgctgcatag gccacacctc caagtatagc tcctcccgca
     2041 gcaccagttg ctgcaccttg ccatgttctt gttttaattc ctagctgaag acctcgtact
     2101 gctcctcctc caacacctgc tttggcaaaa tctccccaat tgcatccgcc accttcaacg
     2161 caagcaagca tctcagtatc cataatttca aattgtgaca tcttttttgt attcataacg
     2221 aatacctctt ttttattttt aatatttgtc ttgttacaaa cttgacaagt ttagtataac
     2281 agtatctatt aatttttttc atccaaatct tgaattggca tcgaaacgtc ttgaattagc
     2341 ttttttgttt caaaatcatc tctattttta aaaaagatgt tttctaatca cttttttact
     2401 attagacttc ctgcaaaact agaatcctag ttcatgattg ataatgccag caatcaaatt
     2461 cattcgtaat ccgaagtgtt tacgatgatt tcgataggtt gttgaaatca ttttaaacgt
     2521 ttttactttg gcaaagatgt tctcaacctt gcttctctcc ttggatagcg catggttata
     2581 ggctttatct tcagctgtta gcggcttgag tttgctggat ttacgtggag tttgtgcttg
     2641 aagatatatc ttcatgagcc cttgataacc actgtcagcc aagattttac cagcttgtcc
     2701 gatatttctc atttctaaaa accatctact tccgttgact tggaactccg attactattt
     2761 tccttgaatg attttaacca catctcctac gttttggagt tggtcaattt cttcatcgct
     2821 gatttcgata ctaaattcat cttccagagt caagataaac tccatcaagt caacagaatc
     2881 cgcatccaaa tcgtctttca gactcaagga ttctgtcacg acaaagtcct ctccctgtcg
     2941 ctcttggata atggtcacaa tacggtcaaa aatttctttt tctgtcatct cttttattct
     3001 cctgaaaatt cacgcgcagt ctgggcaacc acgtctgttt ctagcatggt acggatctga
     3061 cgaatcgtac tataaacagc cttggcatcg cttgagccat gagtcttgac aacaggtgct
     3121 ttaacaccaa acaagaccgc tccaccaaca tctgaataat tgagctgttt tttcaaacca
     3181 ctgaggctgt ccttgagaag gagggcacct agtttcgctc gaagaccacc acctgtaata
     3241 gctgtcttga gcaagcccat gattcccata gctgtccctt cgatggattt gagcacagcg
     3301 tttcccgtga aaccatctgc cacaacaaca tctgcaacgc cattcatcaa atcacgcgct
     3361 tccacgtttc cgataaagtt caaactttca tcagccgcca gtaattcata agtttcctta
     3421 cgaagcgggt cgcccttgct actctctgtt ccgttgttga gcaaaccaac gcgtggttgc
     3481 gcaatgccac ggacattttt agcatagaag gaacctagaa ccgcatattg atggaggtgc
     3541 tgggctgtat tttctgcatt agcaccaagg tctagcatgt caaaaccttt tccatcaacg
     3601 gtaggcaagg tagacatgag tccaggacgg tcgatattct tgatacgacc cacgatgaag
     3661 aatcctgctg ccaacaaggc acctgtattc ccagccgaaa ggacagcgtc tgcttcacca
     3721 tctttgacag ccttggctgc caataccata ctggcatttt tcttattcct aatagctctc
     3781 gtaggttcat catccgaatc aatcttctca tccgtatgga taatgctgac gcgctctgtc
     3841 gctgtcagat attgcttgat tttagcttca tctccgtaaa gttgaacctc gatatctgaa
     3901 aagtcagata gggcttgatt gacaccctca acaatggcct gaggtgcgta atcgcccccc
     3961 atggcatcta ctgcgatttt tttcatttct tttcctcttt tagtaattgt ccccagtctg
     4021 ctagggaatc aataaatttc tttgatttta ggtgaatccc aacgtactct tcatatagtt
     4081 gatccataaa ttggcgtagc tcttgcttga ttccaggctt gagcgaaatg gtctccaaag
     4141 tctcaaaatc aatagcttga aattgattga gcagataggg gatattggga ttgagatgac
     4201 aacgtctctt atcctcatga taatgctctg gacagaggca ggctccatat ttgaaagaaa
     4261 agtcaaaagc ctgaccaacc cgatggcaga agacacactc attaaaattg aggctgattc
     4321 caaatcgagt caaaatttga atttcaaaaa tattggtcaa aacctgataa tccaagcctg
     4381 cttccatcaa ctccaaagtc ttttgcaaaa aagcaaacaa gggagcatcc tgctgattgt
     4441 cctgcaaact agcatctgca agagctgcca cataggtcgc ataggccatg acaaagaggt
     4501 cactattaat cttgggaaaa gtcatgacct catgatagtc ttcgatgtaa ctgagtccgt
     4561 catcattgat tcgcaagaga aatcgtgcca gcaccaaggg ctgaataaca ggcgccagct
     4621 tagactgacc agcgtgtttg acaaaaaaca tgcgtttgcc aacctgctct gtaaaaattt
     4681 tgacgagctt gtcatcctca cgaaaattgc gattgtaaag caccaagcct tgactcgtga
     4741 tagactgaat catgcttctc tcatgtactc ctcaagtcgt ttcatggctt ctttgatagt
     4801 ctccatgctg gctgcataag ataggcggac gtagccttcc ccgtaacgtc caaaggctgc
     4861 accagggata aaggcaacgg ccttcttctg agcaaaatcc ttcagaaaag caaaggagtc
     4921 ttgattgtag cccgctggaa ttttagcaaa aatatagaag gcaccgtctg gtttgataat
     4981 ctcaaaacca agagcagtca ttttttcgat gatatagtcc cgacgttgga tatattcctt
     5041 cttcatgggc tccgcatcgt ttttaccagc cgtcaaggct tctactgcag catgttgcgc
     5101 catggtattt gcggcagtga ccaagtactg gtgactcttg attaactggg ctgtgaaggt
     5161 cgcaggagcg aaaatcagcc ccaaacgcca acctgtcatg gcatgcgatt tagacaaacc
     5221 attgataata atagcctggt ctctcaacat cgttcctaga gacacatggg cttcgcctgt
     5281 gtaggtcaat tctgagtaaa cctcatcaca gacaacaaaa atttcgtact tgcgtaaaac
     5341 agctgccaag gcctctaact gctctcgact gtaggtaatt cctgtcggat tggctggata
     5401 gttgagaata accgccttga gcttatcacc ctgctccaaa atggccttct ccaacatctc
     5461 aggagtcaag acaaaaccat tttcagtcgt atcaatctca acaatttctg ccccaactaa
     5521 gttaacaatc ggttcatagc ctggataagc aggagctggc aaaagtacct tgtctccctc
     5581 ttccaaaata gccgtcaaag tcgcagataa agcctctgtc gccccaattg taaccaagat
     5641 ttcattttca ggagcatagt ccagttggta cttttcctta acaaagtcac tggctgcctg
     5701 acgtagagtc agcagaccac tcatccctgt atagtaggat tggttctgat caatcgctcg
     5761 cttggccgcc tccttgacat ggtctggcgt tgtaaaatca ggttccccca aggtcaaacg
     5821 caagacccca ggaatctccg aaataacctg gtcaaactga cgaatcaacg aaacttgaat
     5881 tttatctaac tgtttattaa agcgcttagt taagtccata gatacctcct actttcaaaa
     5941 cgtatctcta ttatactaca aaagcccccc gaccgcaaaa atacattaga gaatagcttt
     6001 ccactttcta ttttactttt cctgtttata ggtctataat ggtaatagat tttatttgga
     6061 ggtttttatg tcatttctat caaaaaatgg agcaggtatc ttggcctgcc ttctcatttc
     6121 catcctatct tggtacttag gaggattctt ccctgtgatt ggcgcgcccg tttttgccat
     6181 tttcataggc atgctcctac atccctttct ctcgtcctat aaacaactgg atgctggttt
     6241 gacctttagt tccaagaagt tgctccaata tgccgttgtc ttgcttggtt ttggtctcaa
     6301 tatctcgcag gtcttcgcag ttggccaatc ttcactccct gtcatcctgt ccactatctc
     6361 aatagctctg attattgcct acctcttcca gcgtttcttt gcactggata caaaactggc
     6421 taccttggtt ggagtaggtt cttctatctg tgggggttct gccattgcag cgacagcgcc
     6481 tgttatccat gctaaggaaa aggaagtagc ccaagccatt tccgttatct ttttcttcaa
     6541 tgtcttggct gcgctcatct ttccaaccct cggcacctgg cttcatctat ccaatgaagg
     6601 cttcgccctc tttgcaggga ctgcggtcaa cgacacttcc tctgtaacgg ctgccgccag
     6661 cgcttgggac agtctttacc aaagcaatac cctcgagtct gcaaccattg ttaaactcac
     6721 acgtactttg gccattatcc ctatcacgct ctttctatcc tactggcaaa gtcgccaaca
     6781 agaaaacaag caaagcctac aactgaaaaa agtcttccca ctttttatcc tttactttat
     6841 ccttgcctct ctcctcacta cactactcac ctctctaggt gtgtccagta gtttctttac
     6901 ccctctcaaa caactctcta aattccttat tgtcatggcc atgagtgcta tcggtctcaa
     6961 aaccaatctg gtcgctatgg tcaaatccag tggaaaatcc attgttcttg gagccatctg
     7021 ctggattgcc atcatcctca ccactcttgg tatgcagacc cttatcggca ttttctaaca
     7081 ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg ccgtaggtat atgttactga
     7141 cttcgtcagt tctatctaca acctcaaaac ggtgttttga gctgacttcg tcagttctat
     7201 ctacaacctc aaaacggtgt tttgagctga cttcgtcagt tctatctgca acctcaaaac
     7261 ggtgttttga gcagcccgcg gctagtttcc tagtttgcta gtgtgctctt tgattttcat
     7321 tgagtataac acaaaaggta gcccatcagc tacctttttc ttatgcttcc tcaatcaagc
     7381 gagtatgttc tctcttgata cagcgattca tcacgatatc atcacatcca ccatcacgca
     7441 aaatctcttt cgcttctaaa ctttcaagtc ctagctgtgc ccaaaaaatc ttggcatcag
     7501 ctttgagaaa atcacgcgcc acatcgggca gaaattcact gcgacgataa acattgacaa
     7561 tatctacagg aaaaggaatt tcagcgaggc tagcataagc cttttcaccc aagatttcgc
     7621 cacctgccgc cttgggattg actgggatga ttttatagcc ccgagcctgc atttcctttg
     7681 ttactcgatt gctggttgtt tcttcacggt cagacaaacc caccacagca agggttttac
     7741 tcgttgcgag atactgacga atcacgccat cacttggatt gataaattct tgactcatag
     7801 aaatcctcct ttttcatcag tatagcacat tttgaaaagg tttgcagaat tatactacaa
     7861 aaaaggagga ctagccccct ttttatttag cctcgtacca ggttgcccct tcattctcat
     7921 ctgcgataag aggaacactg agttgaatgg cttcttccat ggtttgtttc accaattttt
     7981 tcatctctac caattcagat ttaggcactt caaggacgat ttcatcgtgc acttgtaaca
     8041 gcatcttagt ctgataacca cctgcaacca aggctttatc cagctgaatc atggcaatct
     8101 tgagaatatc tgctgccgaa ccctggatag gtgagttgat agcagttcgc tccgcaaaac
     8161 cacgaatatt gaagttgcgc gaattgatat ctggcaactc acggcgacgc ttaaagaggg
     8221 tctctacata gcccttatca cgcgcctccc gcaccacttc atccatgtag tttttaatat
     8281 ctggaaaacg ttcaaagtag gtatcaatgt aggctttggc ttccttacga ctaattccca
     8341 aattattaga caagccaaag tctgaaatcc cataaaccac tccaaagtta actgccttgg
     8401 cattgcgacg gtcatttgca gtcacattat caggacgctc aatgccaaag acccgcatgg
     8461 ctgtcgaagt atggatatct gccccctctt ggaaggcctt aatcaagtgc tcatccttag
     8521 aaatatgcgc caaaacgcgc aattcaatct gtgaatagtc agagctgagt agcacactat
     8581 cctcccactc tggcacaaaa gccttccgaa tcaagcgccc ttgttccaat cgggcaggaa
     8641 tattttgcaa gtttggatcc acactagaca aacgcccggt ctgggtcaaa tcctgcatat
     8701 agcgagtatg aatctttcca tcagccaaaa tccagtcctg caagccaatt acataagtag
     8761 attgaatctt agcaatttga cggtaatcca ggattttctt aacaatcgga gcaataggag
     8821 cgagacgctc caacacatcc actgctgtcg aataacctgt cttggttttc ttagtgtatt
     8881 ctagaggaag tcccaatttc tcaaagagaa gcacgcccaa ctgcttaggc gagttgacat
     8941 taaactcctc accagccagc tcgtaaatct cttgagtcag tttttcaatg acaagctcat
     9001 tttcagcctg catctcaagc aaggtctctt tcttgaccac aatcccagca atttccatct
     9061 tggcaagaac aaaagccaga ggttgctcca tatcataaag aagctctaat tgcccatttt
     9121 cgctgagttt ttcaagtaaa ataggctctg tttctaccaa aacagcaagt ttacaagcta
     9181 agtgttccaa gaatttctca cgttcaggaa tggccttttt aacaccctta ccgtagaaag
     9241 tttcatcatc aaccaagtaa gtctgaccat aaagactagc gatggtcgca atttcattgt
     9301 cctccacagt cgaaaggagg tatttagcca aacggatgtc aaaagcaggc gcctgcaaat
     9361 ccacaccaaa acgttgcaaa agaactttaa ccttcttaaa gtcataaact ctcagagatg
     9421 ttttttctaa gaaatccttg aaaatcgggt cttgcaacag ctcaagcttg tctgtggcat
     9481 agagcttatc ctcacaagac caggcaaatc caaccaaatt atccgtatgg taattctcac
     9541 caaaaagctc aaagtggaag atagactctt cactcagcat atcttgactg atttggtcaa
     9601 caatagtaaa atccaaaccc ttagccacat cagctgacga cacatttaaa gcctgcttga
     9661 gctgtttgaa tcccatctca tcgtaaaatt tcccaagatt ttcaacatct ggaccactat
     9721 agaccaagtc ctctaaacca atcgcaatcg gtgccttggt atcaatggtc gctagtgttt
     9781 tagacaaaaa ggcctgttcc ttgtcattga tgagattttc cttcatctta gaagtcttca
     9841 ttccatcaat attttcataa atcccctcaa gcgaaccata ctccagcaag agcttaatac
     9901 ccgtcttttc accgactttg gtcaccccag ggatattatc cgacttatca cccatgagcg
     9961 ccttgagatc gataaactga gctggtgtga ggcccatttc ttccatgagg taatctggcg
    10021 taaaggcctc aaactcagcc acacctttct tggaaatttc aaccaccgta tgctcatccg
    10081 tcagctgaat caaatccttg tccccactga caatggtaat atcaaaacca tcctgctctg
    10141 ctagcttatc cagcgtccca atgatgtcat ccgcctcata ctgagccagc tcatagtgac
    10201 gaatccccat atgatccagc aactcacgaa tgaaaggaaa ttgctcacga aactcatcag
    10261 gagtcttggc ccgaccaccc ttatagtccg catacatctc tgtccggaag gtcgtctttc
    10321 ccgcatcaaa agccaccaaa atatgactcg gctcaacccg ctccaacaaa tgactcaaca
    10381 tcaactgaaa accataaatc gcattggtat gcaaaccagc cgcattctta aaacggtcca
    10441 actgctgata cagcgcaaaa aacgcccgaa aagctacaga agacccatca atcaataata
    10501 attttttctt atccatacac ccattataaa ggaaagaatc aaaaaatacc attgggaaga
    10561 gctagagcaa gtatttttca aactttttcc gaataaatag atagagccag agaatttagt
    10621 aaacctagat ttaaaaatgt gctataatat aatatattga atctataata gtacaccttg
    10681 actgctaaaa tatttctata aattaatttg actttcctga tagagttatt cacatcttat
    10741 ttcaactcac tatagaagga ggaataggag gattctcaga catccgggca tcagcccaac
    10801 taatgatttg attgctaaga aaatattcag caatccagaa atcacttgtc aatttattcg
    10861 cgatatgctg gacttgccag caaaaaatgt gaccattttg gagggaagcg atattcacgt
    10921 attactctcc atgccttact cggtgcagga tttttatacc agtatagacg tcttggcgga
    10981 gttggataac ggtactcaag taattattga gattcaagtc catcatcaga attttttcat
    11041 caatcacttg tggacttacc tgtgcagtca ggttaatcaa aatcttgaaa aaattcgtca
    11101 gcgagaaggt gatactcact agagctacaa acacatcgct cctgtttacg ccattgctat
    11161 cgtggatagt aattatttct cagatgacct ggcttttcat agctttagta tgcgcgaaga
    11221 cacaacaggt gaggtattgg cgattaccaa caatggacag gaaaaccatc tggttaagat
    11281 ggcattcttg gaattaaaaa atacagagaa accagcaaag acaaggttcg caagccatgg
    11341 ttggagtttt tcggcaacaa gccctttacc cagcaaccgc aacgagccat tagccaagca
    11401 aatcaactgc tggactacaa gagctggtcc gaggaggaca ggaaaatgtt tagtcaacta
    11461 catatgcgag aagaacaagt cttgttagca caggactatg ccttggaaac tgctagggct
    11521 gaaggccttg aacaaggact agagcgtggg aaagttgaag gaagggcaga aaggaaactt
    11581 tttgccttcc tagacatagt acgccaaggt cttctgactt ctgaggttgc cagccagcaa
    11641 ttaggtatgt cagtatctga atttgaggca ctgttgtaaa atggctccat aatatccata
    11701 gtgggtaaat cccctatgga tattatggag cct
//
LOCUS       DAVKBK010000055        11676 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVKBK010000055 DAVKBK010000000
VERSION     DAVKBK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.055"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            116..919
                     /locus_tag="VWX69_001630"
     CDS             116..919
                     /locus_tag="VWX69_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9192944.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     EVADRIIFMADGEVLVDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            959..1723
                     /locus_tag="VWX69_001631"
     CDS             959..1723
                     /locus_tag="VWX69_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9192945.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQGDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     EFNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            1736..2413
                     /locus_tag="VWX69_001632"
     CDS             1736..2413
                     /locus_tag="VWX69_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9192946.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            2423..3082
                     /locus_tag="VWX69_001633"
     CDS             2423..3082
                     /locus_tag="VWX69_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9192947.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNSVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            3378..4568
                     /locus_tag="VWX69_001634"
     CDS             3378..4568
                     /locus_tag="VWX69_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU9192948.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(4889..5770)
                     /locus_tag="VWX69_001635"
     CDS             complement(4889..5770)
                     /locus_tag="VWX69_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU9192949.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(5911..7239)
                     /gene="vncS"
                     /locus_tag="VWX69_001636"
     CDS             complement(5911..7239)
                     /gene="vncS"
                     /locus_tag="VWX69_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU9192950.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(7236..7892)
                     /gene="vncR"
                     /locus_tag="VWX69_001637"
     CDS             complement(7236..7892)
                     /gene="vncR"
                     /locus_tag="VWX69_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU9192951.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(7941..8024)
                     /gene="pep27"
                     /locus_tag="VWX69_001638"
     CDS             complement(7941..8024)
                     /gene="pep27"
                     /locus_tag="VWX69_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU9192952.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(8204..9583)
                     /gene="vex3"
                     /locus_tag="VWX69_001639"
     CDS             complement(8204..9583)
                     /gene="vex3"
                     /locus_tag="VWX69_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU9192953.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(9635..10282)
                     /gene="vex2"
                     /locus_tag="VWX69_001640"
     CDS             complement(9635..10282)
                     /gene="vex2"
                     /locus_tag="VWX69_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU9192954.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(10295..11572)
                     /locus_tag="VWX69_001641"
     CDS             complement(10295..11572)
                     /locus_tag="VWX69_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9192955.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGNSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         3271 a         2613 c         2228 g         3564 t
ORIGIN      
        1 gatcgatttt tcctgttctt atttcactat agtgaatttt ttcagatatg gtttgacaag
       61 aacattcttt tattgcagaa ttgtgttata aaatctaaca taaaggagtt ctctcatggc
      121 tttagtagaa tttaaaaacg tcgaaaaata ttacggagac taccacgcac tccgcaacat
      181 caatctccgt tttgaaaaag gacaagttgt tgtcctgctt ggaccttctg gctctgggaa
      241 gtccactctt atccgtacga tcaatggttt agaggctgtt gacaaaggaa gtctcctagt
      301 caatgggcac caagttgctg gtgccagcca gaaagatttg gtacctcttc gcaaggaagt
      361 cggcatggtt tttcaacatt ttaaccttta tccacacaaa acagtgttag aaaacgtgac
      421 acttgcaccc attaaagttc taggaattga taaaaaagaa gctgaaaaaa ccgccaaaaa
      481 atatctggaa tttgtaaata tgtgggacaa gaaagattcc tatcccgcca tgctatctgg
      541 tggacaaaaa cagcggatcg ccatcgctcg tggtcttgct atgcatccgg aactcctcct
      601 ctttgatgaa ccaacatctg ctcttgatcc tgagactatc ggagatgttc tagcagttat
      661 gcagaaactg gcgcgtgatg ggatgaacat gatcatcgtt acccacgaaa tgggctttgc
      721 tcgagaggtt gcggaccgca ttatctttat ggccgacgga gaagttttag aggttgcgga
      781 ccgcattatc tttatggccg acggagaagt tttagtagat acgacagatg tcgataactt
      841 ttttgacaat ccaagcgaac ctcgtgccca acaattcctc agcaaaatta tcaaccacga
      901 aagtgacaaa gtcaaataag gaggcgccta tgaaaaaaaa ttctttttat cagcattatt
      961 gattagcctt ttcggccttg ctgctgccaa accagtccag gctgatacaa gtatcgcaga
     1021 cattcaaaaa agaggcgaac tggttgtcgg tgtcaaacaa gacgttccca attttggtta
     1081 caaagatccc aagaccggta cttattctgg tatcgaaacc gacttggcca agatggtagc
     1141 tgatgaactc aaggtcaaga ttcgctatgt gccggttaca gcacaaaccc gcggccccct
     1201 cctagacaat gaacagggcg atatggatat cgcgaccttt accatcacgg acgaacgcaa
     1261 aaaactctac aactttacca gtccctacta cacagacgct tctggatttt tggtcaataa
     1321 atctgccaaa atcaaaaaga ttgaggacct aaacggcaaa accatcggag tcgcccaagg
     1381 ttctatcacc caacgcctga ttactgaact gggtaaaaag aaaggtctga agtttaaatt
     1441 cgtcgaactt ggttcctacc cagaattgat tacttccctt cacgctcatc gtatcgatgc
     1501 cttttccgtt gaccgctcta ttctatctgg ctacactagt aaacggacag cactactaga
     1561 tgatagtttc aagccatctg actacggtat tgttaccaag aaatcaaata cagagttcaa
     1621 cgactatctt gataacttgg ttactaaatg gagcaaggat ggtagtttgc agaaacttta
     1681 tgatcgttac aagctcaaac catctagcca tactgcagat taaggaggac accccatgac
     1741 agatttatca tcttggacag cctattttca ggattttgga caatttttca atggtttcct
     1801 cttcaccctt gccctagcga ttggatcctt tatcctcgcc atggtcttag gaatcttctt
     1861 tggtgccatg tcaaccagta aacgtccaat tttacgcatt ttagctcgca tctttgtgga
     1921 attttaccaa aacactcccc tcttggtgca gtttgttatt gttttttatg gcctacctct
     1981 tatcagtgac catactatca tgattccgat ttattggaca gctgttctct gcgtgggact
     2041 ctatcacggc gcttatatcg ctgaggttat tcgttcaggg attcagtcta ttcctagtgg
     2101 tcagatggag gccgccttat cgcaaggttt tacctatatc agtgccatgc gcttgattat
     2161 cttgcctcag accttccgca tcattctccc tccattgacc aaccaaattg ttaacctcat
     2221 caagaacacc tctactgtag ctatcatctc tggagtagac ttgatgtttg tgactaagtc
     2281 ttggtcggct ctcaacggaa actatatccc agccttttta ggtgctgctc ttctctactt
     2341 tgccctatgc ttccctgttg cccagtttgg tcgcaagatg gagcaagcca acaaaaaagc
     2401 ctattcactt taggaggtta ctatggaatc tattttagaa gttttaaccc cagataacct
     2461 agtctttatc tttaaaggat ttggcttgac cctctatatt tctctgattg ccatcatcct
     2521 ctctactatc atcggtacgg tgctagctgt catgagaaat ggcaaaaatt ctgtcttgcg
     2581 aatcatctcc agtatttata tcgagtttgt gcgcaacgtt cccaaccttc tctggatttt
     2641 tactatcttt ttggtgttca aaatgaaatc cacaccagca ggtattacag cctttactct
     2701 ctttacatca gcagccttgg ctgagattat tcgaggcggt ctcaatgccg tagacaaggg
     2761 acaatacgaa gcaggaatgt cacaaggctt cacctcagcc caaatcctct actacatcat
     2821 tctcccacaa gccatccgca aaatgctacc agccatcatt tctcagtttg ttaccgtgat
     2881 taaggatacc agtctcctct actctgttat cgccctacaa gaactctttg gagccagcca
     2941 aattctcatg ggccgttatt tcgaaccaga gcaggtcttc agtctttaca tcctgattgc
     3001 cctcatctac ttcagcttta acctagcaat ttctagcctg tctcatatgc tagccaaacg
     3061 ttggcaacaa gccgcagaat aatactcttc gaaaatctct tcaaaccacg tcagcttcac
     3121 cttgccgtat atatgttact gacttcgtca gttctatcca caacctcaaa acggtgtttt
     3181 gagcagcctg cgggctagct tcctagtttg ctctttgatt ttcattgagt ataaacagcc
     3241 actctccaat tcaattggag agttttttga tgagagtaga tatttataga cctcaatttg
     3301 acaccataca ttttctatga taaaatgtaa caaattcatt tacaacaaat cgaaatctaa
     3361 atgaaatgga attttctatg aaatcagtca aaggactact ctttatcata gctagtttta
     3421 tcttgactct tttgacttgg atgaacactt ctccccaatt catgattcca ggactagctt
     3481 taacaagcct atctctgact tttatcctag ccactcgtct cccactacta gaaagctggt
     3541 ttcacggttt ggagaaggtc tacaccgtcc acaaattcac agcctttctc tccatcatcc
     3601 tactaatctt tcataacttt agtatgggcg gtttgtgggg ctctcgctta gctgctcagt
     3661 ttggcaatct tgccatctat atctttgcca gcatcatcct tgtcgcctat ttaggcaaat
     3721 acatccaata cgaagcttgg cgatggattc accgcttggt ttacctagcc tatattttag
     3781 gactctttca catctacatg ataatgggca atcgtctcct tacatttaat cttctaagtt
     3841 ttcttgttgg tagctatgcc cttttaggct tactagctgg tttttatatc atttttctat
     3901 atcaaaagat ttccttcccc tatctaggga aaattaccca tctcaaacgc ttaaatcacg
     3961 atactagaga aattcaaatc catcttagca gacctttcaa ctatcaatca ggacaatttg
     4021 cctttctaaa gattttccaa gaaggctttg aaagtgctcc gcatcccttt tctatctcag
     4081 gaggtcatgg tcaaactctt tactttactg ttaaaaattc aggcgaccat accaataata
     4141 tctatgataa tcttcaagcc ggcagcaaag taaccctaga cagagcttac ggacacatga
     4201 tcatagaaga aggacgagaa aatcaggttt ggattgctgg aggtattggg atcaccccct
     4261 tcatctctta catccgtgaa catcctattt tagataaaca ggttcacttc tactatagct
     4321 tccgtggaga tgaaaatgca gtctacctag atttactccg taactatgct cagaaaaatc
     4381 ctaattttga actccatcta atcgacagta cgaaagacgg ctatcttaat tttgaacaaa
     4441 aagaagtgcc cgaacatgca accgtctata tgtgtggtcc tatttctatg atgaaggcac
     4501 ttgccaaaca gattaagaaa caaaatccaa aaacagagct tatttacgaa ggattcaagt
     4561 tcaaataagt aatcatactc tcctgggatt tcccaggaga gttttttata gccaaatgaa
     4621 ataagaccgg aacgatggaa ttttggcatt caaatcaatt gataagaata ttttatagtg
     4681 gagtgaaata ggatacgaac aaattgatta ggaaaatcaa atgaatttat agaaatcttt
     4741 tagcagttat gttgtcctat tctagtttca aaacgctata gaagcagcat tgtactagtc
     4801 tagattcagt ttactatact aaaacgagta gcttgaaatc aaaaaaccca ccctcacagg
     4861 caggttttat ctgtattatt cagctagatt atgctttacc ttctgaaccg aatacgtcga
     4921 tacgttcttc aaccgatgct tggatagctt ttacaccgtc agccaagaat ttacgtgggt
     4981 cgaagagttt tttcttgtcg tattctgctt cgtttgcttc gtagtcacga gcaaatttac
     5041 gagttgcgtt agcgaatgcg atttggcatt ctgtgttaac gttaactttg gcaacaccaa
     5101 gtttgatagc tgcttggatt tgctcatcag gaatacctga tccaccgtgc aatacgattg
     5161 ggaatcctgg aagagcttct gtcaattttt gcaagtggtc aaggtcaaga ccttcccagt
     5221 ttactgggta agggccgtgg atgttaccga taccagctgc caagaagtcg ataccagttt
     5281 caaccattgc tttagcgtct tcgattggag ccaattcacc tttaccgatg attccgtctt
     5341 cttcaccacc gatagtacca acttcagctt ctactgagat acctttagcg tgtgcttttt
     5401 caacaacttc tttagccaat ttaaggtttt cttcaactgg aaggtgtgaa ccgtcaaaca
     5461 tgattgaagt ataaccaact tcgatacact caagtgcatc ttcgtagtga ccgtggtcaa
     5521 ggtggatagc tactggtaca gtgataccca ttgattcaac aaggttagcg atcaagttgc
     5581 gagcaacttt gtaaccaccc atgtatttag cagcacccat tgaagtttgg atcaaaactg
     5641 gagctttttt agcttctgct gcgcgcaaga tagcttgagt ccactcaagg ttgtttgtgt
     5701 taaatccacc aactgcataa ccgttgtcac gggctgcttg gacaaatttt tctgctgaaa
     5761 cgattgccat tttatcaggc ctcctgtata tttttatggg tcatcccatt tacattgttc
     5821 attttatcac tttttgccaa aaaaatctag tttttcccgc agtttcgatt gattttcttc
     5881 taactccatc tatgtaaacc ctttctctcc ctagtcttgg gcgacttttg gaaaagctat
     5941 aaagaaggtt aaacgattct cctccatctc gaaacgataa gctaattttt catgttctaa
     6001 tagactctta accacaaaga gccccatacc agaccccttg accttgcgac tggcattgtc
     6061 agaaaaagac tgggctagtt tttcttgttc ctctgagcta cagctatttt cgataaaaag
     6121 ttctccttct ctttctccaa ttcgaactaa gccacctgga acagagtgct taatggcatt
     6181 gctgatgaga ttagaaagaa tcaacttcat aactgatggg tttagataag cctgctgatg
     6241 ggtcaaacta ttgtctatct ggagctctct ttccttggct agcaaggcat aatctttgac
     6301 cagattttgc gtcatctgga ggaggtcaat tgtttcccta tcatctcgca attcctgcac
     6361 agaagagagg gaaagtatct gcagaacatg gtgattgagt tcatccacaa tccccaaggc
     6421 aactcccaga tactggtctc tatccttata acgaccgata ttctctctca tattttcgat
     6481 taggattttc aaactagcca gcggtgtttt caattcatga gaagctcctc gtaggaattc
     6541 gaccttcatc ttctccagct ggagaatggc ttcattcttt tcatgcaagt ccgcaataac
     6601 agtcaagaga tgctggtaga ggctattgat ttgttccttg agattaccta tctcatcctt
     6661 agaatccacg cgcaatcgca cttgggaatc caggtccatc atccgacggg tcacccgctt
     6721 gatttccaaa atcggtgcaa caatagtccg ggcgtagatg taggccacca agagggaaat
     6781 cagaaaggag gccagcaagg tatagggaag aaactggaga ctgatttgct ccgcttcctt
     6841 ttgtaaatcc atggaagcta gaaactggag aatcatagta ccaccgtctt gcgttttcac
     6901 ctcgcgctcc tcaataaaga gagaggttgt ctggcggtct gtgtccagag gaagactgtc
     6961 cttgacttct aacttgtcct cggtcatctc acctttgacg gtccccttga tatcactagt
     7021 ctgggaatac aagtctaaca cttgctcgat actctgccta tctttccctt ctagggactg
     7081 ggcaatggct gttgcctttt gaccaatggt ttcctgacga tgactcagat aagtcgaagg
     7141 aaaaagaaaa taaatagcta aatgaaggca gataaccaga acactaaata tcgagaaggt
     7201 atagataaat atctttgcaa ataaacctgt tcgtttcatt ttcgctccaa tttataacca
     7261 acattgcgca cagtgaggat acaatccaag tctagctttt tccgcaattc cttgatataa
     7321 acatcaataa cacggtcaaa gggaacctca tctgtcgctt tccagacggc atcgataatc
     7381 tgagaccgag tcaaggcccg gccttcattt ttcactagat agtccagaat ttccaactct
     7441 ttggcattga taggcacttc ttgacctgcg aggcttgcac tgtagctttc aaagtccacc
     7501 ttggtatcct tgtaagaaaa gattcgtcct gtatcgtagt agcgcttgaa aatcgcgtcc
     7561 accctcactt ttaagaggga gagagagaaa ggtttttcca gatagccatc tgccaaagag
     7621 gcaaaggcac tcatcttgta ttcctcatcc tgaaaagctg tcaacatcaa gacaggaacc
     7681 tgactggttt tacgaatctc agctaggact tctaagccgt taagcttggg catctggata
     7741 tccagtaaaa ccagggccac ctcatagcta gaaaattgct ccagagcttc ctgaccgtcc
     7801 gctgcctcaa tagtttcata gccacaatcc gtcaaataat cactgacccc ctcacggatc
     7861 atctcttcat cttctacaat taaaattttc atactttaac tgctctctat tttttatttt
     7921 tcttagaata aatacctact ctattttcta ttatagtctc ttgctggcct tttgtctgta
     7981 agcaactgat cactagataa aacgttgtga aattcctttc tcataaattc cataacttta
     8041 gtatattata tttaagcact aaagtacaaa gaaagcaact gaaagcaatg attttcacca
     8101 ctgctttcag atttattttg aattgttaaa tagctattcc tatccactat tcttgaatag
     8161 aaacacaaga tgcaatcttt attccagact cattttttca aatttattca ccatccagca
     8221 agagctcttt tggttgtttt ctaaggagat tgcttgaagc aagcgccata acgagaacca
     8281 ctagaaccaa ggcaaggaca aaaatgatga taaagtctga tgtctgaatg gaaatgtcta
     8341 ggctcgacaa ggtcttgcta aagccatcta cttctgcacc gccaccaagg ttagaggctt
     8401 gagccgcctt actagcctgt ttggcaacac ctgaagtcac attggcaagg acagtgtttc
     8461 caattgcacg ggcagtgtaa ttagctagga agtaagcaga aactagagca gggatagcaa
     8521 tcaagataga ttcggtgatg aattgaccca agatacttgc ctgcttgagg ccgatagaga
     8581 ggagaattcc cacttccttg cgacgggcgt tgatccaaag gctgagcaag agggcaagga
     8641 ggagaactga gaagctcaag ctaccccaga agaggaggtt ggccatcttg tacataccag
     8701 agatagattg ctcaagagct gggtagttag aggagctctt gacgagtgtg tagctcttcc
     8761 agttgatacc actgatgcca ttcaactctt tcataacatc atccaagttc ttgtctgctg
     8821 ttacaaagaa ggttgcgtcc ccataaatgg ctgtgtcttc tgtgtatcca taaagttttg
     8881 cagcagtgtg aatgtctgta atagctgtgt tttcgtaaag ttcttgtgag taggttactg
     8941 ctgacttatt atgaccatca aagagtccct tgattgtcac ttcaactgtt tccttggctc
     9001 ctttttcatt atctgcatcg tagatattag agtccagttt aaccttgtcc cctactttcc
     9061 agccgtgttt ggctgccaag tccttgtgca agaggatttt atccttgtcg tcgttggtta
     9121 agtgctctcc ttcgactagt ttataagaac cagagacaaa cttgtcttct ttagaggagt
     9181 cattgacacc tgtaatcatc aagctacttc caaaacgttt ggcacgatca gcagtgagat
     9241 tcttcttggt ttctggcgtt tcaatcaggt catatccagt caaatctccg atagcgttga
     9301 tacgtttgac ataagactca atggccttgt tttcggtgat ttttttgatg tcttcaccct
     9361 tgatattccc agcaccgcga ggcgttcctt ggttgacgcg acgattgatt tgcatggaga
     9421 agctattggt gatattttta aaggtctcct gagaagcctt ggcagtagct cccttgattg
     9481 acaagccgac caaactcaag ctcgccatga ggagaataat caggaagatg acaatcgatt
     9541 tgaaaaactt ccttgtaaca taggcaaatg cgttgtgtaa catagattcc ctttctagat
     9601 tttgttttaa tcattctatt aaagtaagct caaattattt actagtattg cgcgtttcag
     9661 tcagtttctt atcctttaat tcaagtgtaa tatctgacgc ttgtgccact tctttactgt
     9721 gagttacgac aatcacacat ttacctgttt tctgggcaag tgatttgagt agttcgacaa
     9781 tatctccagc agttttagga tccagatttc ctgttggctc atcagctaga ataactggag
     9841 cttctgagac caaactgcga gcaatggcaa cacgttgctg ttgaccacct gataactgga
     9901 gaacattccg cttgatctgg ctttcatcca aaccaagctc aagaagtgta ttcttgcttg
     9961 cctttttgtt gaccaatcgg atattttcca gcggagaaag ataatctatc aagttataat
    10021 tttgaaagac cagggaaata tggtgcatgc gatggtaaga atagcccttc ttacgaatat
    10081 cctctccttg aaaaaggata gaaccttcaa caggactatc tagaccagca agtagggaca
    10141 agagtgtgga ttttcctgct cctgactccc caataatact gtaaaatttt ccgggttcaa
    10201 aattataatt gatctgatat aggactgctt cagcagtatt cttataacgg taggtaacat
    10261 cttgtaattg taataaagtc atgatttctc cttcttaact aatagatgat aaaatttctt
    10321 tcggtgattt tctaaataag aataggaaac aaagggctac agataagcaa ctaagcagaa
    10381 ctagaaaaac ataggattct gcaaaagata agatgctagt tgataaactg cttgctttgg
    10441 ctagtgtatc ttgtaagctt gcctgatctc cacttgctag tagagtttgg agtaggtaag
    10501 ttgtgattcc gtttcctgca acaaatgctg gaagcaaagc tccaagagat accaaaacta
    10561 cctctaaaca gaattgtagg aaaatcgagc tcttgccttt tccaagtgca agtaaaatcc
    10621 ccacttcata gacccgttct ctcaaccaga gagacaaaac cagaattaag gctccagctc
    10681 ctgctatcaa catcccataa aggaagatgg tcaggaaggt ttggaaagtt gcaactgagt
    10741 ctttgatttg ttcaaaagcc ttgttttcct tttcgacttg gtagccttga ttttccaagg
    10801 ccaagttttc tacctgcttc atgagtccgt ccatttcctt aggattttct acatagaagc
    10861 gtgctgcact gacttgagct tcactattgc ccaaaagggt ttggctactt tcatagtctg
    10921 taaagacttg attttcactg aagtcagaag acaagcctgt gaatttctct tgttttttac
    10981 cagaaaagat gccgataatc tcaaactcta ctgtttgtcc ttttccagat tcagactgac
    11041 cagcatccaa gccaatcttg tcatgaagtg aaagaccgtt cttcttagcc aattcttcgt
    11101 ggataaggat tttcttggaa ttcccttttt gaaggtgtcg cccttctttt agattgaaag
    11161 ccgaactggt aaaggttaca tccttggatg aatcctcaag agccgttaag ctaaccaagt
    11221 tattgtctgc agctgataaa tcatcacgct ccacgctctg ctcgccagtc actgcttcct
    11281 tgtcttttag ttttgcgacc gtctcgagtt caggagagac attttccagc cccttaatct
    11341 tgcttacaga tgctaggtct gacaacttga atgtctgacc attctctatc ttcttaatag
    11401 aaaaagatgt attgagtgat ttataaagat tgctttctac tgttttgttg gacttcatca
    11461 gagtcaaaca ggctgaaatt ccggccaata agaccaataa aatcagaaat aaaataaaac
    11521 ttctcagtcg ctttctgctg acataagccc aagatctttg gattggattc atttgtcacc
    11581 tccatatttg taagactatt ataaaaccca aatatgaaat gtttatgaaa tacgaaaaaa
    11641 aaatatcgag taggggataa tctctagccc ctctca
//
LOCUS       DAVKBK010000056        11650 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVKBK010000056 DAVKBK010000000
VERSION     DAVKBK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.056"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            168..857
                     /locus_tag="VWX69_001642"
     CDS             168..857
                     /locus_tag="VWX69_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU9192956.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPK
                     EIAQRFINVIK"
     gene            882..1799
                     /locus_tag="VWX69_001643"
     CDS             882..1799
                     /locus_tag="VWX69_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEU9192957.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            1827..3368
                     /locus_tag="VWX69_001644"
     CDS             1827..3368
                     /locus_tag="VWX69_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEU9192958.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAIAIVYSYTGGLKSVLWTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLAIATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGVTGL
                     ILAAIYAAAQSTVSTGLNSVATSWTLDIQDVISKNMSEDRRTKIAQFVSLAVGLFSIV
                     VSIIMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTENKVSAPKYTTIHDISEIKADSS
                     WEVRH"
     gene            3394..3852
                     /locus_tag="VWX69_001645"
     CDS             3394..3852
                     /locus_tag="VWX69_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9192959.1"
                     /translation="MIISEQSDFRRYASVNKHFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            3854..6076
                     /locus_tag="VWX69_001646"
     CDS             3854..6076
                     /locus_tag="VWX69_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEU9192960.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTSISEVQHKSGNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVTRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPAPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIREHGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTQVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQISIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6116..7225
                     /locus_tag="VWX69_001647"
     CDS             6116..7225
                     /locus_tag="VWX69_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9192961.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            7382..8272
                     /locus_tag="VWX69_001648"
     CDS             7382..8272
                     /locus_tag="VWX69_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9192962.1"
                     /translation="MKIIGIDIGGTTIKADLYDDFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYVLNYSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTSEIEKRF
                     GLSTFVENDVNCAALGELWEGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLSSGDKVAKETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNVVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            8297..8620
                     /locus_tag="VWX69_001649"
     CDS             8297..8620
                     /locus_tag="VWX69_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192963.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELISIESNLEMKQQNLIDEVNKTIKENDAKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            8610..10601
                     /locus_tag="VWX69_001650"
     CDS             8610..10601
                     /locus_tag="VWX69_001650"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEU9192964.1"
                     /translation="MAISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFSTIQISHTSNSHHGVIEGNDALNYLMNKQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKW
                     EKLEIIPAHLEQFSFCRGKVGTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETRILYFIKVMDERFGHSIYIYE
                     SETLSDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGIMLALKIFHLPSVTKKFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ITTTSDVMTILVVSVVFGFITVFVGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDIRPLFVLGKWVSIFNAVGILIASIIQAKSLSGIGSGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGTLAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            10617..11093
                     /locus_tag="VWX69_001651"
     CDS             10617..11093
                     /locus_tag="VWX69_001651"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEU9192965.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11127..>11650
                     /locus_tag="VWX69_001652"
     CDS             11127..>11650
                     /locus_tag="VWX69_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192966.1"
                     /translation="MSNLENLRESVIEQAHEKGSMKLLDSKKKIDDEFEMQKSVIVKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTL"
BASE COUNT         3925 a         1659 c         2320 g         3746 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccaaa agaaattgct cagcgattta
      841 ttaatgtcat caaataaaaa acaatataaa ggagaaatct gatgaaagat ttaactaaat
      901 acaaaggcgt tattcctgca ttttatgctt gctatgatga aaatggtgaa attagccaag
      961 aacgtgtaaa atctctggtg caatatttca ttgacaaagg tgtaaaaggt atctatgtaa
     1021 atggttcttc aggtgaatgt atttaccaaa gtgtagaaga tcgtaaacaa attattgaag
     1081 ctgttatgga agttgctaaa ggtaaattaa cagttatcaa ccatgttgca tgtaataaca
     1141 cgaaagatag tattgaattg gcaaaacatt cagaaagtgt tggagtcgat gctattgctg
     1201 ctatcccacc tatttacttc aaattgccag aatattcaat tgcagcatat tggaatgcaa
     1261 tgagtgaagc tgcgccaaat acagatttta tcatttataa tattccacaa ttggcagggg
     1321 ttgcgttgac tggtagtttg tatgcaacaa tgcgtcaaaa tcctcgtgtg attggagtta
     1381 aaaattcttc tatgcctgta caagatattc aaatgtttgt agctgcaggt ggagaagatt
     1441 acattgtatt caatggtcca gatgaacaat atcttggtgg tcgcttgatg ggagcagaag
     1501 ctggtattgg tggtacttat ggcgttatgc cagatttgtt cttgaaattg gaaagtttga
     1561 ttcaagaacg agatttagat actgctaaaa aacttcaata tgctatcaat gaagttatct
     1621 ataagatgat atcaggtaag gcaaatatgt atgctgtagc aaaagaggtt ttgcgtctaa
     1681 atgaaaaact tgatttaggt tctgttcgtc aacccttaga agcattggca gaaggtgact
     1741 tggaagttgc aaaacaagca gcagaactta ttcaacaagc acgaaaagaa tttttataat
     1801 aaataaaatc aatatggaga tatgttatgg gcacaacagg atttacaata attgacttaa
     1861 ttatcttgat tgtttattta cttgcggtgt tggttgcagg tatctatttc tctaaaaaag
     1921 agatgaaagg aaaagagttc tttaaaggag atggttcggt tccttggtat gttacttcgg
     1981 tatccatttt tgccacaatg ctcagtccga tttccttctt gggactcgct ggtaactctt
     2041 atgcaggtag ctggatttta tggtttgctc aattagggat ggttgtagct attccactga
     2101 caattcgttt tatcttacct atctttgcac ggatagacat cgatacggca tatgattact
     2161 tggataaacg ttttaattct aaagcacttc gtattatttc agcactcttg tttattattt
     2221 atcaattggg acgtatgtct atcattatgt acctcccatc agctggttta tcagtattga
     2281 caggaattga catcaatatt ttgattattt tgatgggtgc aattgcaatt gtttattctt
     2341 atactggtgg tctaaaatcc gtattatgga cagactttat tcaaggtgtg gttctgatta
     2401 gtggtgtcgt tgtagcttta tttgtactga tggctaatat taaaggtggc tttggtgcag
     2461 tagcagaaac attagcaaac gggaaattcc ttgctgcaaa tgaaaaactt ttcgatccta
     2521 acttgctttc aaactccatc ttcttaattg tgatgggttc aggctttaca atcttgtctt
     2581 cctatgcttc atctcaagat ttggttcaac gttttactac aacacaaaat attaagaaac
     2641 ttaataaaat gttgttcaca aatggtgtct tgtcacttgc aattgcaaca gtcttttact
     2701 tgatcggtac aggcttgtac gtattctatc aagtacaaaa tgcaggtagt gcagctagca
     2761 atatccctca agaccaaatc tttatgtact ttattgcata ccagttacca gtaggtgtca
     2821 caggtttgat cttggcagcg atttatgcag cagctcaatc aactgtttca acaggtttga
     2881 actctgttgc aacttcatgg acattggata ttcaagatgt catttctaaa aatatgtcag
     2941 aggatcgtcg tacgaaaatt gcacaattcg tatctctagc agtaggttta ttctcaattg
     3001 ttgtttccat tatcatggct cattcagata ttaaatctgc atacgaatgg ttcaatagtt
     3061 tcatgggact tgtacttggt ctacttggtg gtgtattcat tcttggtttt gtttctaaaa
     3121 aagcaaataa acaaggtgct tatgcagcgc tgattgtatc aaccatcgtt atggtattta
     3181 ttaaatactt ccttcctcca acagctgtta gctactgggc atattcattg atttcaattt
     3241 ctgtatcagt agtttcaggt tatattgtat ctgttcttac tgaaaataaa gtatctgcac
     3301 ctaaatatac aacgattcat gatatttcag aaattaaagc ggattcaagt tgggaagttc
     3361 gtcactagtc actaatagaa aagagaaaat aatatgatta tttctgaaca atctgatttt
     3421 agacgatatg cttctgtcaa taaacatttt tcaaaagtct gtgatttttt agaaaataca
     3481 aatttgacag atttagttga tggaaaaatt gatattgacg gggaaaatgt ttttgcaaat
     3541 tgtatgactt atctagctga tggagttcca ggagatattt ttgaaactca taagaaatat
     3601 ttagatattc atattgttgt tgaaaataca gaaaaaatgg cagtaacttc cccagttcgt
     3661 gctcagtcac gtgtaccttt tagcgaagag aaggatattg ctttttacga tagcaaagac
     3721 tatcaaattg ttgaattgct tccagggaat atgttggtga cttttgaaga agatcttcac
     3781 caaccaaaga ttcattgcaa tgatgaaact gttaaaaaac ttgttatcaa agttttaaac
     3841 gaggaaaaat aaaatgaaaa aaaatattaa acaatatgta accttaggta ctgtagtggt
     3901 attatcagca tttgttgcta actcagttgc agctcaggag actgaaactt ctgaagtatc
     3961 aacaccagag ttggtgcaac ctgttgcacc aacgacttcg atttcggaag tacaacataa
     4021 atcgggtaac tcttcggaag ttactgtaca acctcgaaca gttgaaacta ctgttaagga
     4081 tccatcttct acagcggaag aaactcctgt cttagaaaaa aataatgtta ctttaacagg
     4141 gggcggagaa aatgttacta atgagttaaa ggataaattt actagcggtg actttactgt
     4201 agtgattaag tacaatcagt ctagtgagaa aggtttacaa gctctgtttg gaatatctaa
     4261 ttctaaaccc ggtcaacaaa atagttatgt agatgtgttc cttagagaca atggtgaatt
     4321 gggaatggaa gcgcgtgata cttcttccaa taaaaatcac ctagtaacca gacctgcttc
     4381 agtttggggt aagtacaaac aagaggccgt gacgaacact gttgcagtag tagcagattc
     4441 agtcaaaaaa acgtattctt tatatgcaaa tggtacaaaa gtagtagaaa agaaagtgga
     4501 taacttccta aacatcaagg atattaaagg tattgattac tatatgcttg ggggagtgaa
     4561 acgtgcagga aaaacggcgt ttggttttaa cggaacacta gaaaatatca aattctttaa
     4621 tagtgcattg gatgaagaaa ctgttaaaaa gatgacaaca aacgctgtta ctggacattt
     4681 aatttatacg gctaatgata caacaggttc taactatttc cgtattccag ttctgtatac
     4741 ttttagcaat ggtcgggttt tttcaagcat tgacgctcgt tacggtggaa ctcatgattt
     4801 cttgaataaa attaatattg ctacaagtta tagtgatgat aatggtaaga catggactaa
     4861 accaaaatta acattagcat tcgatgattt tgcgccagca ccattagaat ggcctcgtga
     4921 tgttggtgga cgtgacttac aaatcagcgg tggtgcaacc tatattgact ctgttattgt
     4981 tgaaaaaaat aacaaacaag tactcatgtt tgctgatgtt atgcctgctg gagtaagttt
     5041 tagagaagct actagaaaag attcaggtta taaacaaatt gatggtaatt attaccttaa
     5101 attaaagaaa caaggtgata ctgattataa ttatactatt cgtgagcatg gtactgtata
     5161 cgacgatcgt accaacagac caactgaatt ttcagtagat aaaaatttcg gtattaaaca
     5221 aaatggtaat tatttgacgg tagagcaata ttcggtttca tttgaaaata ataaaaagac
     5281 tgaatatcgt aatgggactc aagtccatat gaatatcttc tacaaagatg cattattcaa
     5341 agtagtgcca acgaactata ttgcatatat ttctagcaat gatcatggcg aatcttggtc
     5401 tgcaccaact ttattacctc ctataatggg acttaatcgg aatgcgcctt atttgggtcc
     5461 tggacgtgga atcattgaaa gctcaactgg acgtattctt attccgtctt acactggtaa
     5521 agagtctgca ttcatttata gtgacgataa tggagcgtct tggaaagtta aagttgtgcc
     5581 acttccttct agttggtcag cagaagcaca atttgtagaa ttgagtccag gagtaattca
     5641 agcatacatg cgtacaaata atggtaaaat tgcatattta acaagtaaag atgcaggtac
     5701 tacttggagt gcgccggaat atttgaaatt tgtttcaaat ccaagttatg gaacacaatt
     5761 atcaatcatc aattatagtc aattgattga tggtaaaaag gctgtcattt taagtactcc
     5821 aaactccaca aatggtcgta aacacggaca aatttcgatt ggtctaatta atgatgataa
     5881 tacaattgat tggcgttatc atcacgatgt tgattatagt aactatggat actcatattc
     5941 aacattgaca gagttaccaa atcatgaaat tggattgatg tttgaaaaat ttgattcatg
     6001 gtctcgtaat gaacttcata tgaaaaatgt tgtaccatat ataacattta agattgaaga
     6061 tttgaaaaag aattaaagct gaaatttaaa aatatataga aagaggataa aaattatggt
     6121 aaattacggt attgttggag ctggatattt tggagctgat ttggctcgct caatgaacaa
     6181 aattgaagat gcaaaagtgg ttgcggtatt tgacccaaat catggagaag aagttgctca
     6241 agagttggga tcagatgttt gtgcaagttt agatgaactt gtagcacgtg aagatattga
     6301 ttgtgtgatc gtagcttcac ctagctacct tcaccgtgaa cctgttgtga aagctgctca
     6361 acatggcaaa cacgtatttt gtgaaaagcc aattgcattg tcttatgaag attgtaaagc
     6421 catggttgac gcatgtaaag aaaataatgt tatctttatg gctggtcaca tcatgaactt
     6481 ctttaatggt gtacaccatg ctaaagaatt gattactcaa ggtaaaatcg gtaaagttct
     6541 ttattgccat gccgctcgta caggttggga agaacaacaa ccaactgtat catggaagaa
     6601 acttcgttct caatctggag gacatttgta ccaccatatt catgaattag attgcattca
     6661 gttcatcatg ggaggacttc ctgaaaaagc gacaatggta ggaggcaatg tatatcataa
     6721 aggtgaaaac tttggtgatg aagatgatat gctcattgta aacctagaat actctgatga
     6781 tcgttatgct gttttggaat atggtaatgc tttccgttgg ggtgaacact acgtcttgat
     6841 tcaaggaact gaaggagcta tcaaacttga cttgttcaat actggaggta ctcttcgtgt
     6901 taaaggtgaa ggagaatcac acttcttagt acatgaaact caagaggaag atgatgaccg
     6961 tacagctatc tataccggtc gtggtatgga tggagcaatt gcgtacggta aaccaggagt
     7021 acgttgccca ttatggttac aaacatgtat tgataaagaa atggaatatc tacatgacat
     7081 cattaaaggt ggagaaatta cagaagaata tgaaaaactt ctcaatggtg tagctgcttt
     7141 agaatcaatc gctaccgctg atgcatgtac tttatcagtt aaagaagatc gaaaagtaag
     7201 tctttcagaa atcacaaatg cttaactatt gtaaaacaga atagtaaatt cttgtcatta
     7261 tataatttct aaagttctgt gatacaactc attgaataaa gaaatagaga tgggactggg
     7321 ataatgccca gtcccatttt ttatcaaaaa gtaatgagat caaaaatgtg ggagtgatga
     7381 aatgaagatt atagggatcg atattggcgg aacaacaatt aaggcagatt tatacgatga
     7441 ttttggaacg agtttaaatc agttcaaaga gatagaaaca attattgact atgatttggg
     7501 aacgaaccag atattaaatc aggtctgtga tttaattggt gagtatgttt taaattattc
     7561 aattgatggt gttgggattt ccactgctgg agttgttaat gctaatacag gagaaatcat
     7621 ctatgcaggc tatacaatac cagggtatat cggagtaaac tttacttccg aaatagaaaa
     7681 acgttttggg ttgtctactt ttgttgaaaa tgatgttaat tgtgctgcat taggtgaatt
     7741 gtgggaggga caagccaaag ataagaaaaa tgtagtaatg gttactattg gaacaggtat
     7801 aggaggcagt attattgtca atggacaaat tgttaacgga tttaactata ctgctggtga
     7861 agtaggctat attcctgtag gtaattcgga ttggcaaagc aaagcctcaa caaccgcatt
     7921 gattcattta tatcaaaaga agagcttgaa aactaatcaa actggacgta ctttctttac
     7981 tgatttaagt tctggagata aagtcgctaa agaaactttt gaaatttttg tagaaaatct
     8041 aacaaaaggt ttattaacta tttcttatct acttaatcca gaaattctca tattaggagg
     8101 tgggattctg gctaaaaagg atattttgtt acctgaaatt caaagttctt tagctaaaaa
     8161 tgcaatggat aataggtttt tgcctaaaaa tgttgtggca gctacattag gaaatgaagc
     8221 tggtcgtata ggagctgtaa aaaatttctt agatagaatt tctaataaat agtgtgaaag
     8281 ataaggaggt gtcacaatga ctaactctgt attttcgaca atgcaagata ttgagaatgt
     8341 tgcaaccgat attataaaat catatgataa tgagatttat acgtataaag ctgtctccca
     8401 agaagaattg gaaaaactag aaaaaagtta tgatgaaaaa agtcacgaag aattaatttc
     8461 aatagaaagc aatttagaaa tgaaacaaca gaacctcatt gatgaggtta ataaaacaat
     8521 caaggaaaat gatgcaaaga ttcagtatat ttcatcaagt aggagaggag aatttgtaga
     8581 aaaaattatt ggtagggtgg tagaaaaata tggctattag tcagatgaaa agaatttctc
     8641 tactatttac taagagtagt cttgatgatg ttttaaaaac tattcaagaa ctagagtcag
     8701 tgcagttccg tgatttaaag gttcaggata actggtcaga agcgctagaa aaagatgagg
     8761 ttgtattttc aactattcaa atttctcaca cttctaattc ccatcatggg gttattgaag
     8821 gaaatgatgc cttgaattat ttgatgaata aacaacaaca tttggaagca actgtagaga
     8881 aattacaaga atacctaccg aaagaaaaca cgtttaagtt attacagcaa cctccgataa
     8941 caacctctta tgaagaatta gaaaaatttg gtaaagctaa tgttgctgag ggtgttctta
     9001 aaaaagtgaa tcatcaaata aacagagttc atgaattaga aagaaacatt caaagtaata
     9061 atgaggaaat agagagatta ataaagtggg aaaaattaga aattattcct gcgcatttag
     9121 aacaattttc tttctgtaga ggaaaagtcg gaacaattcc aaggactgta gataatcgct
     9181 tatacaataa ttttttagaa aacaatattg aagttcaaga aatattttct aatgatagag
     9241 agtacggtgt tgttgttttc tatcagtcca gttgctctat tgattttgat gaatacttat
     9301 ttgaaccatt tgattattct agaaaggaat taccgaagca gcgagtagta gatttggatc
     9361 aagaaaacat gcagttaata actgaaaaag agaatattat cgcatcgttg caagattcaa
     9421 agaaaaattt gatagattta caatggcaaa ttgactatat tttatctatc tatgctcgtc
     9481 aaatctctaa gaataacctt ttgagcactc cgcatctagt tgcattagaa ggatggatag
     9541 aagaaactcg tattttatat tttataaaag ttatggatga gcgttttgga cattctattt
     9601 atatttatga atcggaaaca ttgtcggata atcaagatga aatacctatc aaattaacga
     9661 atcactcttt aattgaacca tttgaattat tgacagaaat gtatgctctg cccaaatatt
     9721 atgagaaaga tcctacacct gtattagcac cattttactt tacatttttt ggaatgatgg
     9781 ttgctgattt aggctatggt ttactattgt ttttaggaat aatgttagca ttaaaaattt
     9841 ttcatctacc ttcagtaact aagaaatttt taaaattctt taatatatta ggggtagccg
     9901 ttgcaatttg gggtggaatc tatggctcat tttttggata tgagttgcca tttcatctga
     9961 taactacaac ctcggatgtc atgactatat tagtagtgtc agttgtgttt ggatttatta
    10021 cagtatttgt aggtttgtta gcttcaggac tacaaaaagt aagaatgaag aaatatgcag
    10081 aagcatataa ttcaggattt gcgtggtgtg ttattctgct tggcttgtta tttattgctg
    10141 tcggaatgtt gatgcctgat attagaccgt tatttgtatt agggaaatgg gtatctattt
    10201 ttaatgctgt ggggattttg attgcttcta ttattcaagc caaaagcttg tcaggtattg
    10261 gctcaggatt gtttaatcta tataacattt catcttatat aggtgattta gttagtttca
    10321 ctcgattgat ggcattagga ttatctggag caagtatagc atcagctttc aatttaattg
    10381 ttggtttgtt tccggggaca ttggctaaac tgacaattgg attagtatta ttcattcttt
    10441 tacatgcgat caatattttt ctatcgttac tatcaggata tgttcatgga gcgcgtctga
    10501 tatttgttga attttttggt aagttttatg agggtggagg aaaaccattt caacctttga
    10561 aggcttctga gaaatatatt aaggttatta caaagaatta atggaggata tatataatgg
    10621 aacatttagc aacttatttt tcaacctatg gaggagcttt cttcgctgca ttgggaattg
    10681 tattggcggt tggattaagc ggtatggggt ctgcttatgg agttggtaag gctgggcaat
    10741 ctgccgcagc tttactgaaa gaacagccag aaaaatttgc ctcagctttg atattgcaac
    10801 tattgcccgg aacacaagga ttatatggtt ttgttattgg aattttgatt tggttgcaat
    10861 taactccaga acttcctttg gaaaaaggcg ttgcttattt ctttgtagct cttccaattg
    10921 ctattgtagg atacttttcg gctaagcatc aaggaaatgt agcagtagcg ggaatgcaaa
    10981 tcttggctaa aagaccaaaa gaattcatga agggagcaat tttggctgcc atggtagaaa
    11041 cctatgcaat tcttgccttt gtcgtatcat tcattttgac ccttcgtgta taagaaatta
    11101 atttgctatt caaaggaggt gtctaaatga gcaatttaga aaacttacga gaatctgtta
    11161 ttgaacaagc tcatgaaaaa gggagtatga aattattgga ttccaaaaag aagattgatg
    11221 atgaatttga aatgcaaaag tcggtcattg taaagaaaaa agaagctgaa catgaacgaa
    11281 agttaaaaga attacaacag aaatatcaaa taatttttca acaattaaaa aataaggaac
    11341 gccaatcaac gttagtatca aaacagaaaa tattaaaaga actttttcaa tctgctttaa
    11401 tagaaatgga atcttggagt gcagataaag aaatggagtt catctatcga attctggaac
    11461 gatattcaca acaagaggtc atagtaactt ttggggagcg gactttagct aaattcaatt
    11521 tggaacaatt agagaaattg aaattctctt ttccaaatca tttatttagt gaacagccta
    11581 tctcaaatga atcaggctta cttatttcaa taggtaaaat tgatgataac tatttgtata
    11641 aaacgttaat
//
LOCUS       DAVKBK010000057        11595 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVKBK010000057 DAVKBK010000000
VERSION     DAVKBK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.057"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            436..1146
                     /gene="deoD"
                     /locus_tag="VWX69_001653"
     CDS             436..1146
                     /gene="deoD"
                     /locus_tag="VWX69_001653"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9192967.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1169..1693)
                     /locus_tag="VWX69_001654"
     CDS             complement(1169..1693)
                     /locus_tag="VWX69_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU9192968.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1746..1982)
                     /locus_tag="VWX69_001655"
     CDS             complement(1746..1982)
                     /locus_tag="VWX69_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU9192969.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(2050..2970)
                     /locus_tag="VWX69_001656"
     CDS             complement(2050..2970)
                     /locus_tag="VWX69_001656"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU9192970.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3161..3564
                     /locus_tag="VWX69_001657"
                     /pseudo
     CDS             3161..3564
                     /locus_tag="VWX69_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3780..4361
                     /locus_tag="VWX69_001658"
     CDS             3780..4361
                     /locus_tag="VWX69_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9192971.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4358..5635
                     /locus_tag="VWX69_001659"
     CDS             4358..5635
                     /locus_tag="VWX69_001659"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU9192972.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5653..6315
                     /gene="deoC"
                     /locus_tag="VWX69_001660"
     CDS             5653..6315
                     /gene="deoC"
                     /locus_tag="VWX69_001660"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU9192973.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6302..6691
                     /locus_tag="VWX69_001661"
     CDS             6302..6691
                     /locus_tag="VWX69_001661"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9192974.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6782..7834
                     /locus_tag="VWX69_001662"
     CDS             6782..7834
                     /locus_tag="VWX69_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU9192975.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7978..9513
                     /locus_tag="VWX69_001663"
     CDS             7978..9513
                     /locus_tag="VWX69_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192976.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGAINADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            9506..10564
                     /locus_tag="VWX69_001664"
     CDS             9506..10564
                     /locus_tag="VWX69_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9192977.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10567..11523
                     /locus_tag="VWX69_001665"
     CDS             10567..11523
                     /locus_tag="VWX69_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9192978.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         3306 a         2077 c         2653 g         3559 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg acgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttgatgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc
      961 aaggctgtgg aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat
     1021 gcgctagcta tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca
     1081 gaagaacgtc aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca
     1141 gaataattat agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca
     1201 gaaattgatc tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc
     1261 aaagtttttg gtaattttct ttttgagttt tgctacgccc atcccaaaga atccatctga
     1321 taaactccca ctcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac
     1381 ggtatttaag ataacgctta aaggctctaa agagacaggt caatggcaaa aaattgagaa
     1441 agatgatttg gtcagcttct tgcattcgtt cttggtagta gcaccaagaa taattaccat
     1501 cgatgaccca agctttatgc ttggtgagaa agttttttat ctcggttaac atccattcgc
     1561 agtcactgtc ttgccaacca ggttgaaatt ggagtgtgtc catgtgcagt tttggaatgg
     1621 agtagtagtt agataacttt tctgctagag ttgacttacc agaaccagaa tatccgataa
     1681 ttgtgatttt cattttctac cttttcctat ttggagacaa aaaaacagcc tctatggact
     1741 gtttcttatt tagcaagttt agttgaaaga cgagctttat cgcggcttgc tttgtttttg
     1801 tgaatcaaac ctttagtttc tgctttatcg atagctgagc tagcagcacg gaaaagttct
     1861 tcagatgggt ttgcttcgaa agcttttata gcagtacgca tagctgattt ttgagctgag
     1921 ttcttttcgt tttgtttaac gttcaattca gcgcgtttga tagctgattt aatgtttgcc
     1981 aatgttctta cctccatatt tactaactat accattatat atgaaaactt acgttttgac
     2041 aagggaaaat tactttttta agtaaatttc atcgatttca tggttcttgc ttttatgaag
     2101 aatcacttct gcacgatttc tggttggttc aatataattt tgcagatttg tgagattgat
     2161 actgatccag acctgatggg caaaggactc cacttcccca atcggcatct gagtaaaacg
     2221 ataatagtag ctatcagggt cgttttgggc taggctcagc atcttcaaga aacggtccag
     2281 ataccaactt tcaatatcat ctactccagc atctacatag atggaaaagt caaagaagtc
     2341 agtgatatag agacgatcgt tttgtggatt ttgaaagaca ttaattccct caacaattac
     2401 aaaatcagca gctttgacac tttgtttctt ttcgggtacg atgtcgtaaa cttcatgaga
     2461 atagacagga atatctacat cttgtccatt tttgatgcgg tccaagaagt tgagaagagc
     2521 ttccatatca tagctttcag gaaatccttt acgatttaaa atcccctgct caatcaaggt
     2581 ttgattggga tagagaaaac catcagttgt aaccaactca accgtagcat ctgtaaacgt
     2641 acgggacagt aggatttgaa gtaggcgact ggttgtggat tttccaacgg caacactccc
     2701 agaaacccca ataataaaag gttgagattt actttcacgt tggaggaaaa ttccttttga
     2761 aaaggctaaa tcttccttag ttcgcttgta aatctgaatc agatgagcca aggggagata
     2821 gatatctgta acgtcttgga gactgatttg gtcattaaaa ctcttgatag attccaattc
     2881 ttcttctgtc aaaggaggtg ttgtctttcg atgtaaagat tgccaagtct ggcggctgat
     2941 tttttcaaaa tgtaaaaatt cgttggtcat ttgttttccc ctagatattt tgtctatcat
     3001 accataaaaa gctaaaaaaa taaagcggtt tcttgaatgt ggtaagtcaa tggtatatag
     3061 tataagtgat caatttattg atgaaatagg agatagattc tactgattta taagcttata
     3121 aagggggctt tttagttcac aacttagtag gaggtgtact atgaaaatct taaaacgtta
     3181 tatattggaa ctctgtttta ttttaagttt tgctttacct tttataaaag gaaccaatgc
     3241 agataatggt agatgctttg tggaaaccta ttacggtttt acttttttga tggaacatgc
     3301 tattgtaaca gctgtcttta tctgttcgtt cttaattgct ttcttactaa aaaacgatgg
     3361 acgaaatgga ttgctgcggg tagttattgc tttttagtcc tacggattgc gacagagggt
     3421 tatttcttcc acatgtcact agaagatttg atacgacttt ggacaagttt ggaaatcctg
     3481 acacaaacgt atcagttggg cttttatcta aacattttgt taggaatttt gttgataata
     3541 aagtatttta aggttaagca atagaaataa taatctgcct gattatagat gataaacttt
     3601 ttgtttttat ctggactgtg atatttatag ttctaaatgg tttattattt ataagtgttg
     3661 aaagagattg aagaaaatgg cttcgtgact tgctttcttc ggtctttttc gttttattat
     3721 caatttgtaa acgatttaca atttgagtca aattatggta aaatagtgtc atgagtaaaa
     3781 tgtactatgc agaaaatcct gacgctgctc acgacattca tgagttgaga gtggacttgt
     3841 tgggagaaaa aatgactttt ttgacagatg cgggtgtttt tagcaagaaa atggttgact
     3901 ttggaagtca actcttgctc aagtgtctgg atgtcaacca aggagagaca gtcctagatg
     3961 taggctgtgg ttatggtcca ttaggtttgt ccttggtcaa ggtttacgga gttcaggcga
     4021 ccatggttga tattaacact cgtgccctgg atttagctca gagaaatgct gaaaaaaata
     4081 atgcaaaagc gacgatattt caatctaata tttatgcaag agttcaaggg cgatttgacc
     4141 atgtcatttc caatcctcct atccgtgcgg gcaagcaagt cgttcatgaa atcatcgaga
     4201 aaagtaaaga tttcttggaa attggtggag atttgaccat cgtcatccag aaaaaacaag
     4261 gagctccaag tgccaaatct aagatggaag atgtgtttgg caattgtgaa atccttaaaa
     4321 aagacaaggg atactatatc cttagaagtg tgaaagaatg agagcagttg atttaatcca
     4381 aaaaaaacga gacggtcaag aactgacttc aagtgaaatt gaatggctga tagaaggcta
     4441 tgtatcagga actgttcctg attatcagat gtctgccttt gctatggctg tttattttaa
     4501 aggaatgacg actcgagaaa tctctgattt aacgatgaat atggttaaga ctgggcaaga
     4561 gtttgacctg tcagccattg atggtgtgaa agttgacaag cattctactg gtggtgtcgg
     4621 cgataaggta accttgattt tagctcctct tgttgctagc ttcggtgtgc ctgtagcaaa
     4681 aatgagtggt cgtggtcttg gccatacagg cggaacaatt gataaattgg agtccattag
     4741 gggctatcaa gtagaacgta gtcaagagga ttttattcgt caggttcagg atattggagt
     4801 atctgtcatt gggcaatcag accagctggt caaagcagat aagcttctct atgcccttcg
     4861 tgatgtgacc gcaactgtcg acacgattcc tttgattgcg agttcggtga tgagcaagaa
     4921 aattgcggca ggggcggatg ctattttgct agacgtgact gtcggtgagg gtgccttcat
     4981 gaagacggtt gatgaggcgc gtgagttggc tcaaactatg gtagatcttg gtaaggttgt
     5041 tggacggaag acagtagcag tgattacgga tatgagccag cctttggggc gagcgattgg
     5101 aaatcgtctg gaaatccttg aagcattgga gattttgcaa ggtcaaggac gtcaggatat
     5161 tacccacttt atttgtgaat tggctcaaat tatgcttggt ttggcaaatg ttaacaaaac
     5221 tgttgaagaa gttcgccaac atcttgaaaa tggtcaagca ctggctaagt ttgaggaaat
     5281 ggtgcaagcc caaggtggag acttggaaga cctctatcgt cctgtaaatg tagctcatgt
     5341 ggtggaaatc cctgctcagg aaacgggtgt catttcagct cttccagcta tggactttgg
     5401 tctttatgcc atgaggctgg gtgctggtcg tgcagttaag tctgatgtct tggactatga
     5461 aacaggaatt gtttttgaaa agaagattgg agactccgtt caaaagggtg aaattgttgc
     5521 aaaagtatac acaaatgaaa aaattccacc tcaactagtt acagatttcc aaaaatgtgt
     5581 taaaataagt gatgaagtga aaaaaatccg tgaaattgta gaaatcatct cctaaatgga
     5641 gggaaaaccg aaatgaaatt aaataaatat atagatcata cgcttttaaa acaagatgca
     5701 aagaaaaaac aaattgatag tttgttgtct gaggctagag agtatggctt tgccagtgtt
     5761 tgcgttaatc cgacctgggt tgaacatgct aaaaaaggac ttgaaggcac agatgttaag
     5821 gtttgcacag tagtaggttt ccccttggga gcaacaactt caactgtgaa agcttttgaa
     5881 acaaaagaag ctatccaaaa tggggctgat gagattgaca tggtaatcaa tgttggggct
     5941 ctcaagtcag gtgatttggc cttggttgag tcggatattc gtgcagtagt ggaagcaagt
     6001 ggggacaagt tagtgaaagt tattattgaa gcttgccttc tgacagacca agaaaaagtt
     6061 ttggcttgcc aattagccca aaaagcagga gctgactttg tcaaaacatc tactggcttt
     6121 tcaactggtg gtgctacgat agcagatgtt agattaatgc gtgaaacagt tggacctgat
     6181 atgggtgtca aggccgccgg tggagctcgt tcttatgcag atgctcttac ctttgtcgaa
     6241 gcaggtgcga cccgtatcgg aacgtcagct ggggtagcta ttttaaaagg agaattggca
     6301 gatggcgact actgagttga ttgaactggc aattgaaacc agcaaacatg cctatgtccc
     6361 ctattctcac tttcctatcg gagcagtttt agtagccaaa gacggaagtg tttacacggg
     6421 agtgaatatc gaaaatgcta gctatccttt gaccaattgc ggtgagagaa cagctatttt
     6481 taaggctata tctgaaggcc aaagagaatt ttcagaattg attgtctatg gtcaaactga
     6541 aaaaccgatt tcaccatgtg gtgcttgtcg ccaagtaatg gtcgaatttt ttgaacaaga
     6601 tttaaaagtg accctagtcg caaaagataa atcgacggtc gagatgacgg tcggggagtt
     6661 acttccatac tcttttacag acttaaatta gtctgagtcg ctctttgagt ggcaagggtc
     6721 tttgtgacca atcaatccat acttgcaaca tcgttgcaca tcttatttag gaggttcagt
     6781 aatgaacaag aaacaatggc taggtcttgg cctagttgca gtggcagcag ttggacttgc
     6841 tgcatgtggt aaccgctctt ctcgtaacgc agcttcatct tctgatgtga agacaaaagc
     6901 agcaatcgtc actgatactg gtggtgttga tgacaaatca ttcaaccaat cagcttggga
     6961 aggtttgcaa gactggggta aagaacacaa tctttcaaaa gataacggtt tcacttactt
     7021 ccaatcaaca agtgaagctg actacgctaa caacttgcaa caagcggctg gaagttacaa
     7081 cctaatcttt ggtgttggtt ttgcccttca caatgcagtt gaagaagcag ctaaagaaca
     7141 cactgacttg aactatgtct tgattgatga tgtgattaaa gaccaaaaaa atgttgcgag
     7201 cgtaactttc gctgataatg agtcaggtta ccttgcaggt gtggctgcag caaaaacaac
     7261 taagacaaaa caagttggtt ttgtaggtgg tatcgaatct gaagttatct ctcgttttga
     7321 ggcaggattc aaggctggtg ttgcgtcagt agacccatct atcaaagtac aagttgacta
     7381 cgctggttca tttggtgatg cggctaaagg taaaacaatt gcagccgcac aatacgcagc
     7441 cggtgcagat attgtttacc aagtagctgg tggtacaggt gcaggtgtct ttgcagaggc
     7501 aaaatctctc aacgaaagcc gtcctgaaaa tgaaaaagtt tgggttatcg gtgttgaccg
     7561 tgaccaagaa gcagaaggta aatacacttc taaagatggc aaagaatcaa actttgttct
     7621 tgtatctact ttgaaacaag ttggtacaac tgtaaaagat atttctaaca aggcagaaaa
     7681 aggagaattc cctggcggtc aagtgatcgt ttactcattg aaggataaag gggttgactt
     7741 ggcagtaaca aacctttcag aagaaggtaa aaaagctgtc gaagatgcaa aagctaaaat
     7801 ccttgatgga agcgtaaaag ttcctgaaaa ataatggatg gaagtcattt cttaggaagc
     7861 ggccaagggc cgctttttta agagttgaga caaagtcatt ttgtctcagt aaagcttgct
     7921 actagacaaa ctagcaagtt ttattgaaat aaaataagac tctgaaagga agagcacatg
     7981 gcacacgaaa atgtcattga gatgcgtgat attaccaagg tgtttggtgg atttgttgcc
     8041 aacgacaaaa tcaacttgca cctacgaaaa ggtgaaattc atgcactttt aggagaaaat
     8101 ggggctggta agtccacgct aatgaacatg ttagcaggcc ttcttgaacc aaccagtggt
     8161 gaaatcgcgg tcaacggtca agttgtcaat ctcgactccc catctaaagc agctagcttg
     8221 ggaatcggga tggttcacca gcactttatg ttggttgaag ccttcacagt ggctgaaaac
     8281 atcattttag gtagtgaatt gactaaaaat ggtgtgctag atatcgctgg agctagcaaa
     8341 gaaatcaagg ctctttctga acgttatggc ttagctgttg acccttctgc caaggtagca
     8401 gatatctcag ttggagccca acaacgtgta gaaattttaa aaacacttta tcggggggct
     8461 gatatcctta tctttgacga accaacggct gttttgactc catcagaaat tgatgagttg
     8521 atggctatta tgaaaaatct tgtcaaagaa ggaaaatcaa ttatcttgat tacccacaaa
     8581 ttggatgaaa ttcgcgcagt ttctgaccgt gttacagtta tccgtcgtgg gaaatcaatt
     8641 gaaaccgttg aaattgcagg ggctatcaat gctgatttgg cggaaatgat ggtaggacgt
     8701 tctgtttcct ttaaaacaga gaagcaagcc tctaaaccaa aagaagtggt tttgtctatc
     8761 aaagatttgg tggtcaatga aaaccgtggt gttccagctg ttaaaaatct gtccttggat
     8821 gttcgtgctg gagagattgt tggtattgcg gggattgatg gaaatggtca gtctgaactg
     8881 attcaagcca ttacaggtct tcgtaaggtt gaatctggta gcattgagct aaaaggagat
     8941 tcaattgtag gcttgcaccc acgtcagatt acagaactaa gtgttgggca cgttccagaa
     9001 gaccgtcacc gtgatggctt gattttggaa atgatgatat ctgaaaatat tgcccttcaa
     9061 acctactata aagaaccaca tagtaaaaat ggaattttga attattcaaa tattacttct
     9121 tatgctaaaa agctgatgga agagtttgat gttcgcgctg ccagtgaatt agttcctgca
     9181 gctgcactct caggaggaaa tcaacaaaaa gcaattattg ctcgtgaaat tgatcgagat
     9241 cctgatctcc ttatcgttag ccagccaact cgtgggttgg atgtcggtgc cattgagtat
     9301 atccacaaac gcttgattga agagcgtgat aatggcaagg ctgtccttgt tgtcagcttt
     9361 gaattggatg agattttaaa cgtctcagac cgtattgccg ttatccacga tggtaagatt
     9421 caaggtattg tatcaccaga aacaaccaat aaacaaggac ttggtgtctt gatggctggt
     9481 ggaaacttgg gaaaggagaa gagtgatgtc taaaaaatta caacaaattt cggttccctt
     9541 gatttctgta ttcctaggaa ttttactcgg agccattgtc atgtggatct tcggttatga
     9601 tgctatttgg ggctacgaag aattgttcta tacagccttt ggcagtctgc gtgggattgg
     9661 agaaatcttc cgtgctatgg gtcctctggt cttgattggt cttggttttg cggttgccag
     9721 tcgagctggt ttctttaacg tcggacttcc tggtcaggct ttggcaggtt ggattctcag
     9781 tggttggttt gccctgtcgc atccagatat gccccgtccc ttgatgattc tagcaaccat
     9841 cgtgattgcc ttgattgctg gtgggattgt cggagcgatt ccaggtattc ttagggccta
     9901 tctagggacg tcagaggtta ttgtaaccat catgatgaac tacattgtct tgtatgtagg
     9961 gaatgccttt atccatgctt tccctaaaga cttcatgcaa agtacagatt cgaccattcg
    10021 tgttggggct aatgcaacct atcagacacc ttggttagct gagttgactg gtaactcacg
    10081 gatgaatatt ggtattttct ttgccatcat tgccgttgca gttatttggt tcatgctcaa
    10141 gaaaacaact cttggttttg aaatccgtgc agttggtctt aatccacatg cttcagaata
    10201 tgctggtatt tctgccaagc ggactattat cctatctatg attatttcag gtgccttggc
    10261 aggtcttggt ggagctgttg aaggtttggg aaccttccag aacgtctatg ttcaaggttc
    10321 gtcattagct atcggattta acggaatggc ggttagtttg cttgcggcca actcaccaat
    10381 tggtatactc tttgcagcct tcctatttgg cgttctccaa gttggggctc ctggtatgaa
    10441 tgcggcgcag gtaccatctg agctcgtcag cattgtaaca gcgtctatta tcttctttgt
    10501 cagtgttcat taccttatcg aacgctttgt caaaccgaaa aaacaagtta aaggaggtaa
    10561 gtaaagatgt ctattataac cttgctcccc ctcttggtgt cttctatgct gatttactca
    10621 gcacctctca tctttacaag tatcggtggt gttttctctg aacgtggtgg tgtggtaaac
    10681 gttggccttg aaggaattat ggttatgggt gccttttctg gagttgtctt taaccttgaa
    10741 tttgcagaac aatttggagc agcaactcca tggctatcct tgcttgtagc aggattggtt
    10801 ggtagtgttt tctctatcat ccacgcagca gcgacggttc atttccgtgc agaccatgtt
    10861 gtcagcggta cggtattgaa cttgatggcg cctgccttgg ctgttttctt agttaaagtt
    10921 ctttataaca aaggacaaac cgacaaccta agtcaaactt ttggacgctt tgatttccca
    10981 gtcttggcaa atatcccagt gattggtgat atcttcttca agtcaactag tctacttggt
    11041 tatctggcga ttgccttctc attccttgct tggtttattc tctttaagac tcaatttggt
    11101 cttcgtctcc gctctgtcgg tgaacatcct caagcagcgg ataccttggg aatcaacgtc
    11161 tacaagatga gatatttagg ggttattatt tcaggttttc taggtggaat tggcggagcg
    11221 atttatgcgc aatcaatctc agttaacttc tcagtgacaa ctattgttgg acctggattt
    11281 atcgcccttg ctgcgatgat ctttgggaaa tggaatccaa tcggtgctat gctttctagt
    11341 ctcttctttg gactttcaca aagtttggct gttatcggtt ctcaattgcc gttcctacaa
    11401 ggagtgccag cggtttatct tcaaattgca ccttatgttt tgacaattct tgtcttagca
    11461 gccttctttg gaaaagcagt cgcaccaaaa gcagatggta tcaactacat caaatcaaaa
    11521 taagcataca aaaaaacgtc agtccaatga ctgaactgcc ccccaaaagt tagacagaaa
    11581 aaatctaact tttgg
//
LOCUS       DAVKBK010000058        11516 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVKBK010000058 DAVKBK010000000
VERSION     DAVKBK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11516
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.058"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(56..286)
                     /locus_tag="VWX69_001666"
     CDS             complement(56..286)
                     /locus_tag="VWX69_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU9192979.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(454..1098)
                     /gene="pcp"
                     /locus_tag="VWX69_001667"
     CDS             complement(454..1098)
                     /gene="pcp"
                     /locus_tag="VWX69_001667"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU9192980.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(1113..2036)
                     /locus_tag="VWX69_001668"
     CDS             complement(1113..2036)
                     /locus_tag="VWX69_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU9192981.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(2033..2722)
                     /locus_tag="VWX69_001669"
     CDS             complement(2033..2722)
                     /locus_tag="VWX69_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU9192982.1"
                     /translation="MEWIRLIGIAIIVVGFIFKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(2787..3491)
                     /locus_tag="VWX69_001670"
     CDS             complement(2787..3491)
                     /locus_tag="VWX69_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9192983.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(3547..4569)
                     /locus_tag="VWX69_001671"
     CDS             complement(3547..4569)
                     /locus_tag="VWX69_001671"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU9192984.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(4701..7172)
                     /gene="parC"
                     /locus_tag="VWX69_001672"
     CDS             complement(4701..7172)
                     /gene="parC"
                     /locus_tag="VWX69_001672"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU9192985.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(7592..9535)
                     /gene="parE"
                     /locus_tag="VWX69_001673"
     CDS             complement(7592..9535)
                     /gene="parE"
                     /locus_tag="VWX69_001673"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU9192986.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGFKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAVVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            9671..10312
                     /gene="plsY"
                     /locus_tag="VWX69_001674"
     CDS             9671..10312
                     /gene="plsY"
                     /locus_tag="VWX69_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU9192987.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(10355..11516)
                     /locus_tag="VWX69_001675"
                     /pseudo
     CDS             complement(10355..11516)
                     /locus_tag="VWX69_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3271 a         2574 c         2032 g         3639 t
ORIGIN      
        1 ctctcctaca atcaacatgg actattatat catgaaaatt tcaaaaaaac aagacttatt
       61 ttgctaaatt ataattttca atcaaaattt ccacagcttt ttccaatttt ttataaaaac
      121 tatcgacatt cccattcttt ataatggcaa attgtccgtc taattcggca atttctccga
      181 taactttttt accgatagtc aatgtataac cttcaaaact gtctttacca acattaactt
      241 tggcatccgc tacttgaatt tcgatttttt tatctttctt gctcatttca tacctctctt
      301 cactttttct attttacaag aaaatcctaa aactagcaag aaaaaactct atatcaggct
      361 tctctgatat agagttttat gtaaacaacc tcaatcgatt tagcatagct aatagttagt
      421 aaacaagcat aattgactat cctttttagg ttatcagtga gtctcaccgc ctactaactg
      481 caaatcctta tctttgtagt ctacaatagc ttcaatagct acctctatgc ctcttacaat
      541 atcacataga ctcattcctg cagtattcgg cttatttact acttgttcca tcatatatgg
      601 aatatgcatg aaacctgctc tcatattagg gaatttttta tccactaaat aaagagcttg
      661 gtacatcaaa tgattgcaaa caaaggttcc tgcactattg gatacaactg ccggaagtcc
      721 ctgttttttg atagcttgta ccatcgcttt gataggtaaa ctactaaaat aggccgatgc
      781 tccatcaata cgaatcggtg tatcaattgg ttgattgcct tcgttatcag gtatgcgagc
      841 atcatcttga ttaatagcca ctcgttcagg tgttaagccg gtcctgccgc ctgcttgtcc
      901 aatacaaagt acagcatctg gttgatatcg taatatttct gcctctaaaa cttctgacga
      961 cttataaaaa accgttggaa tttctaccca gcgaacttca gccccattaa tctcagatgg
     1021 taataatttt acagcctcca aagctggatt aatcttttca cctccaaaag gattaaaacc
     1081 tgtaaccaat attttcattt tattttcctt tactaaaatg cgagaaagta cattaagaat
     1141 atgtgaataa caatcattac tagagcaaca cctgcttgag cctttataac gccattctga
     1201 tctttcatat ccatcaatgc tgctggtaga gcgttaaaat tagcagccat tggggtcaat
     1261 aaggtcccac aataacctgc tgtcatggca agagcaccag ccacaattgg attagctccc
     1321 agagcaaata caaagggaac tccaacacct gctgtaataa cggtgaatgc tgcaaaagca
     1381 tttcccataa tcattgtgaa tagaaccatt ccaagaacat aggccaaaac tcctataaag
     1441 cgactatctg aaggaacaat accgctaatc agatgagaga taacatcacc aacacctgct
     1501 acagtaaaaa tagcccccaa agcccctaat aattgaggaa caataccact tgttgaaact
     1561 tgctgagtca ttcgattatt ttctgataac agactcttag ggtgactatt ggtaatcaca
     1621 agaacagaaa ttgtagcaaa caaggcggca aggctaatcg aaatcttgct aaattctgga
     1681 atcatttgcg ctaagaccaa cgcaagtatt gccatcagca taactggaat aaaaatttta
     1741 tttttcaacc tgttagattc aatattggct ttcatttcat ctaaggatgg caaggttccg
     1801 atacggactt gcttaaacaa tgttaacagc gataatagga ttacaataat accaatactc
     1861 atatttggca tataggaacc acctataaac gtaatagaca atagagtcca aaatgcagat
     1921 gtcccaagtc gaactgggtt tgttttatct ttataactac aataggctgt atggagaaat
     1981 tgacaaccaa tcacaatata ggtcaactct aatagttgct ttgccaactc tgtcattttt
     2041 gttctcctcc cctagtcttt tttgatatca attttttatc aaataaataa ttgtaaatcc
     2101 ccactacaat aagtgttata acagcaacaa taatagatgt agaagcaatc cctgcataat
     2161 tgctttcata gcctaactga tctaatgttc cccctatcaa gaggactccc ccagcaccta
     2221 caaacgtatt ttgagcaaag aaatttccaa aattttcatt cgcagccgca cgcgctttta
     2281 ttgtctcatc ttcaacctct gttaactttc tacctaattg agactctgca gctgcttctc
     2341 ccataggttg aaccaaaggt ctgacaaact gagggtgtcc tcctagacga attgaaaaga
     2401 aaccagctaa ctctcgaata aaaaaataaa ctgtatagaa gtttccaact gtcagacctt
     2461 taatctttcg aatcaaatcg attgatcgtt gcttgagtcc aaaggtttct gacagcccca
     2521 caagaggcaa ggtaaccata aaaatcgtga gcactcgctg attgctaaat tcttttccca
     2581 aaatctccaa aaattcaacg agagaaacac ctgaaactaa agctgtaacc aaaccagcta
     2641 agactactgt tgcaattgta tcaaatttaa aaataaaacc cacaacaatg attgctattc
     2701 ctattaatct aatccactcc atatcaaact cctttatatt caaaatgaca gtattttaaa
     2761 aattttatca agatcaatac cattccttat ttaatgtatt tttctagttc tttttggtat
     2821 ttgctattgg attccaattt ttctttttgc cattttttaa aaacctcgtt atattctttt
     2881 gttgtaacaa tatctttttg caatttcatt cctttaaaga tatatggttc ccccttaata
     2941 ccaacttgtg agtatggttt tgagaatggt actacgttac ttacaactgg agaaccacca
     3001 gatgaagctg ttggcatcaa taatgaacta tctgtcgacc aagcttgagc tttggcatat
     3061 ttttcatatc tcttctctag gtcagtggtc tcagaaacag catcttctaa caatttctta
     3121 tatttatcca aaccaggttt agctacaaca tccttatctt ttcctttcgt aataccaagg
     3181 tgtttcatgg cagaaccaga ttttggatcc ataatattca agtaagacgc tggatcttga
     3241 tagcttggag cccatcctgt actattcaaa tcatagtctt tttgagaagg agcaacattg
     3301 ccgtatttat cattttccat caaaccatca ataacatttc caataacgtc tgtcctcgat
     3361 gttcgagtcg ctatactgta gcccaatgat gctggatcta ctgcatagac ataagaaaat
     3421 gttgtcggtg catctgcttc tttatcagtt tttccacaag ccactaaaat agctgacgtg
     3481 ctcaggacca ctcctgctgt taagagccac tttttctatt tcataaaaaa tctcctttgg
     3541 tttattttaa tctactttta caatccaacc ttctggcgct tcaatatcgc caaactgaat
     3601 acccgtcaat tcattatata atttacgcgt cacaggacct acttctgttt cactatagaa
     3661 tacatggaaa tcatcaccat gttgaatacc tccaattgga gaaataaccg ctgctgtacc
     3721 acaggcacct gcctctacaa aacggtcaag attatcaatt ggaacatcac cctcaatagg
     3781 agttaatccc aagcgatgtt ctgccaaata aagcaaggaa tacttggtaa tagatggcaa
     3841 gatagatgga ctcaatggtg ttacaaattc attatcagct gtaattccaa agaagttagc
     3901 tgatccgact tcttcaatct ttgtatgagt tgatgggtcc agatagataa catctgagaa
     3961 atgacgtgac ttggccattt ttcctggtaa gagacttgca gcatagtttc caccaacctt
     4021 agccgcacct gtaccatttg gtgctgcacg gtcgtactca tcctgaatca agaagttggt
     4081 tgggaccaaa ccacctttaa agtaatttcc aactggcata gcaaagatgg tgaaaatgta
     4141 ctcttctgcc ggttttaccc cgataatatc tccgacacca atcaaaagag ggcgaagata
     4201 taaggttcca cctgttccgt atggtggtac gtattcttca ttcgcacgga caactgcttt
     4261 acaagcttct acaaacatgt ctgtcggaac ttgtggcatc aagagacggt cacatgtacg
     4321 ttgcagacgt ttagcatttt catcaggacg gaacagttga acactgccat ccttagtacg
     4381 ataagctttc aaaccttcaa atgcttgttg tccatagtga agacttggag aagactctga
     4441 aatatgcaaa gttgcatcct ctgtaagctc tccttgatcc cattgtccat ttttgaaatg
     4501 agcaagatag cgataaggta atttcatata ggaaaaaccg aggttttccc aatcaatcgt
     4561 tactgtcata ttccactcct tattctaaaa acctatttct tatattctac actatttttc
     4621 taaaatagca agtatatttt gtaattttca gaaaatttct ccaataaaaa ccagctctta
     4681 gaactgattc ttcatttcac ttatttatct tcagtaacta cttcctgaag ataagcgtca
     4741 aaaacttctt catctgaaat cgtgtcagaa atgaagcttc cattgctagt gcgttctgac
     4801 aagttcaagt cttgcaatcg gctttcatag attgttcctt tattggattg gacaagcaga
     4861 gtttggtcgt tcacatccac ttccgtactg aagaaatcgc caacaaatcc ttgctctgca
     4921 actgctcctg ccaagaagac acgatgcggt ttgtttttca actcacgcaa gacttgtaat
     4981 cctcgtttgg cacggctggt tgctagaatt tcctcaatgg aaacacgttt caagcttcca
     5041 cgctgggtca agaggtagaa ggacgaagta ttacagataa agccagattg gaggacatca
     5101 tcttctttca aattcatagc cttgacacct gctgccttag caccgacaac cggaacctct
     5161 tcgatattga aacgcagggc ataaccattt tgactaacca agacaacatc atctagttta
     5221 atcggagcca ctgctacaat ctgatctgta tcgtctttga gcttagcata cttgacagac
     5281 ttagatctat aggtccgcca tggagtgaat tcttttcgct ctacccgttt gatttgacca
     5341 aggcgagtca ctgcaaagta ggttgtcgca tcgtcaaact gatccagtac ttccacataa
     5401 aggatttctt cattcgtttc aaagtttgtg atggtttggc tcagatgctc tccgatgtcc
     5461 ttccaacgaa tatctgccaa ctcatggatt ggtctgtaga tgacatttcc aagacttgtg
     5521 aacatcaaga ggtgctgggt tgtcttggca gattgaacaa aaatcaaacg gtcatcatca
     5581 cgcttgccaa tttcttccaa ggtggaagcc gcaaaggaac gtggactggt acgcttgatg
     5641 taacctgcct tggtcacgct gacgtaggta tcttcctcag cgataagact agctgtatca
     5701 atctcaattg ctttcgcagt gtcttctaaa gaactcaaac gaggagttgc aaatttcttc
     5761 ttgacctcac gaagttcttt cttcatgaga ttgtacatag tcctttcatc accgataata
     5821 gccgccagca tagcaatctt ctcacgaagc tctgcttctt cttcctgcaa gacaaccaca
     5881 tcggtattgg tcaaacggta cagttgcaaa gttacgatag cctcagcctg ttcttccgta
     5941 aaatcatagc taactttgag gttttccttg gcgtccgcct tattctcaga agcacggata
     6001 agagcaatga cttcatccaa aatcgaaatc acacgaatca aaccttcgac gatatggaga
     6061 cgtttctcag ccttttcttt gtcaaagcgt gaacgcgcca aaatcacttc tcgacggtga
     6121 gcgatgtagc tagacaggat tggaacaatc ccaacctgac gaggtgtgaa attgtcaatc
     6181 gccaccatat taaagttgta gttgatttgt aggtcggtgt acttaaataa gtagttgaga
     6241 acaagctcag tattagcgtc tttcttaagt tcgatagcga tacgaagacc atcacggtca
     6301 gactcatcac gaacctcagc aatcccagct accttgttat taacacgaac atcatcgatt
     6361 ttcttgacta gattggcctt attgatttca taaggaatct cagtaataac gatttgttcc
     6421 ttaccacctt ttagcttttc aatttcagtc ttggaacgaa caaccacgcg ccctttccca
     6481 gtttcataag ctttcttgat ttcatcacga ccctgaataa tagcccctgt agggaagtct
     6541 ggtccaggca agaattccat gagtttatca atctttgcag ttgggtggtc aatcatgtaa
     6601 actgcagcat ctatgacctc agctaaatta tggggaggaa tgtctgtggc ataaccagcc
     6661 gaaatcccag tcgaaccatt gaccaagagg tttggaaagg ctgctggcaa gaccgttggt
     6721 tctttctccg tatcgtcaaa gttccatgca aaaggaactg tatttttctc gatatcctga
     6781 agaaggtaac ctgcaatttc agacaaacgt gcctcagtat aacgcatagc cgcaggagga
     6841 tctccgtcca tagaaccgtt attaccgtgc atttcaacta gaatctcacg atttttccag
     6901 ttctgtgaca tacgaaccat ggcatcatag atagaagaat ccccgtgtgg gtggaaattc
     6961 cccatgatgt tcccgactga cttggccgac ttacggtagc tcttgtcaaa agtattgcta
     7021 tccttattca tagaataaag aatacggcgc tgaaccggct tcaacccatc acgaatatct
     7081 ggcaaagccc ggtcttgaat aatgtacttg gagtagcgac caaagcgctc tcccatgatg
     7141 tcctccaggg acatgttttg aatgttagac ataagataca aagcccataa aataccaagt
     7201 gaaaatagaa aattcttgaa gtaagcaaac tcacaagaga atttatcttt ttcacacagt
     7261 atctagggcg tgttcaactc ctttcaaaga atgtagagta ggtttttatg cagtaaaaga
     7321 tattttacgg gaattcctcc cgtgttcagt tacgataagt aaccaaacta tcctgtttgt
     7381 atttttcaat atgaaaatct ggttttccaa aattagtctt agtttgtgtc ttagccgctc
     7441 ccttaagcgc ctctttgaga taagcactca tagcagattc ttcattaata atcctgcaat
     7501 tttttcaaac caagattttc aaactgcttt ttcacatagt cattcacatc cgactctaat
     7561 ttccagttta ctaacatatt attttctttc attaaaacac tgtcgcttct tctagcgtaa
     7621 acttgacatt atcttcaatc catttacggc gtggttctac cttatctccc atgagaacat
     7681 tgacgcggcg ttcggcgcgc gctaaatctt caattgtgac acggatgagg gtacgtgttt
     7741 ctgggttcat ggttgtttcc cagagctggt ccgcattcat ctcaccaagt cctttgtatc
     7801 gttggagggt agcgccttta ccgaactgtt tacggagttc ttctagttct ccgtccgtcc
     7861 aagcgtaggc cacttcttct ttcttgcctt tacctttgga catcttataa agaggtggga
     7921 gggcaatata gacatgacct gcctcgacta gcggacgcat gtaacggtag aaaaatgtca
     7981 agagcaaggt ctggatatgg gcaccgtcgg tatccgcatc ggtcatgata atgatcttat
     8041 catagttggc atcttcaata gagaagtctg ctccaacacc cgcaccaatg gtataaatca
     8101 tggtattaat ctcttcattt ttgaggatat ccgccatctt ggccttggct gtattgacaa
     8161 ccttaccacg aagaggtaga atagcctgga acttgcggtc acgaccttgt ttggcagaac
     8221 caccggcaga gtccccctca actagataga gttcattctt agcaggattc ttagattggg
     8281 ctggggtcaa tttcccagac aacaagccct tatctttctt gtttttcttc ccatttcggc
     8341 tctcatcacg cgccttacgt gctgcttcac gagcatcacg ggccttgata gccttgcgga
     8401 tgaggttaga agctaattcc ccattttcca taaggaaaaa ggtcaactta tcagccacta
     8461 ttccatccac aactgggcga gctagggggc ttcctagttt atccttggtc tgtccttcaa
     8521 actgcaagtg ttcttcagga actaagatag aaagaacgac cgctagtccc tcacgatagt
     8581 ctgaaccttc aaggttttta tctttttcct tgagaagacc tgttttacgt gcatagtcat
     8641 tcatgacctt ggtaatggca gacttgaatc ctgtctcgtg cgttccaccg tccttggtgc
     8701 gaacgttatt gacaaaggat agaatgttat ctgagaatcc gtcattgtac tggagggcta
     8761 cttccacttg aaaaccattg tcttcccctt caaagtaaag aactggcgtc aagatttcct
     8821 tatcttcgtt gagataagaa acaaaatctt gtactccatt ctcatagtgg aactcaatcg
     8881 cttcatctgt tcgcttgtcc gttaaagaca aggtcacatt tttcaagaga aaggctgatt
     8941 cattaaggcg ctctgaaatg gtattgtact tgaaatctgt cgtagaaaag atagtcgcgt
     9001 caggcataaa agtaactttg gtgcctgttt tagacttggg tgctgtaccg attttcttca
     9061 aagtcgtgac aggttttcca ccattttcaa aacgttgctt gtaaactgcg ccatcacggg
     9121 taatttcaac ttctaaccag ctagaaaggg cgttaacaac ggaagaaccc actccgtgaa
     9181 gtccacctga tgtcttatag ccaccttgac cgaatttccc tccggcatga agaatggtaa
     9241 agataacctc aacagttgga attcccatag cgtgcatacc tgtcggcatc ccacgtccat
     9301 ggtcttgaac cgttagacta ccgtctttat tgatagttac atcaatacga tcaccaaacc
     9361 cagacaaggc ttcatcgact gcattatcaa cgatttccca aactaggtga tgaagaccag
     9421 cgccatcggt cgatccaata tacatccctg gacgttttcg gaccgcatcc aacccttcta
     9481 gcacctgaat agcatcatca ttataattgt taatattgat ttcctttttt gacacaagga
     9541 acctcctatt cgttcatctt tactattcta caggttttcc aaggattttg caaaattttt
     9601 ctttctccga tgtgacaatt tcagcagaga ttctctgctt ttctttccca attcatgata
     9661 taataggagt atgattacaa tagttttatt aatcctagcc tatctgctgg gttcgattcc
     9721 atctggtctc tggattggac aagtattctt tcaaatcaat ctacgcgagc atggttctgg
     9781 taacactgga acgaccaaca ccttccgcat tttaggtaag aaagctggta tggcaacctt
     9841 tgtgattgac tttttcaaag gaaccctagc aacgctgctt ccgattattt ttcatctaca
     9901 aggcgtttct cctctcatct ttggactttt ggctgttatc ggccatacct tccctatctt
     9961 tgcaggattt aaaggtggta aggctgtcgc aaccagtgct ggagtgattt tcggatttgc
    10021 gcctatcttc tgtctctacc ttgcgattat cttctttgga gctctctatc ttggcagtat
    10081 gatttcactg tctagtgtca cagcatcgat cgcggctgtt atcggggttc tgctctttcc
    10141 actttttggt tttatcctga gtaactatga ctctctcttc atcgctatta tcttagcact
    10201 tgctagtttg attatcattc gtcataagga caatatagct cgtatcaaaa ataaaactga
    10261 aaatttggtc ccttggggat tgaacctaac ccatcaagat cctaaaaaat aaaacgccag
    10321 ttctgtactg accccaaaaa gttagacaat taatttatcc gaaggattta gttctgtatt
    10381 gcacagggct aagtcctttt agttttacct taattcgttt attgttgtag taatcaatat
    10441 agtctacaat ggcttgttcc aattgcttaa gcgactgaaa cgacttctca taaccgtaaa
    10501 acatttccga tttcagaatc ccaaagaagg actccatcat accattgtct gggctgttac
    10561 ccttacgtga catggatgct tgaattccct taccctcaag aaactgatga taagaatcgt
    10621 gttgatattg ccagccttgg tcactatgga gaatcgtatt ctcgtagtgc ttctctgtga
    10681 atgcctgttc caacattgtt tgtacttgtt ctaagttggg tgaagttgaa agattatagg
    10741 cgataatttc gctgttaaaa ccatctaaaa ctggtgataa gtaaagcttt tgagtactta
    10801 ctggaatggc aaattcagtc acatctgtgt agcactgttc cattgtttta gagccttcaa
    10861 attggccttg aatgagattc tctgctttct taccaacgtc tcctttatga gaagaatatt
    10921 ttcgtttctg tcgcatttta gcttgtaaat tgagtacttt catcaagcct tgaactcttt
    10981 tatgatttac cagataacca cgatttctta gttctaaata aatccgacga taagcataat
    11041 ttcccttgtg ttcgataaaa atggattgaa tttcagcttt aagctcttgg tccttatctg
    11101 gtttgtctag ctgtttcaag tgatagtagt aggtcgaacg agctagttta atggctttta
    11161 gaagaatatc taacgaaaac tcagtcatta attcttgaac aatttctgtc tttcttcttt
    11221 ctctttttcc tccttcaatc ggagttctct taactttttt aggatggcat tctccgctct
    11281 caggtactca ttttctgctt gaagatgttc taattctgtc ctctcttcag gtctcttttt
    11341 tggcttacgt cccattttag gtactctccc tcttgttttc tcaacaatag tatacccgtt
    11401 tttttctgta ttgtgctagc cagttaagaa gtatcgtacg acttgggaga ccgtattcaa
    11461 gagaaactct gtctttagtc cagccttcat gtcagacttt attaatcatt tcttgt
//
LOCUS       DAVKBK010000059        11157 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVKBK010000059 DAVKBK010000000
VERSION     DAVKBK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.059"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            10..1005
                     /locus_tag="VWX69_001676"
                     /pseudo
     CDS             10..1005
                     /locus_tag="VWX69_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1031..1675
                     /locus_tag="VWX69_001677"
     CDS             1031..1675
                     /locus_tag="VWX69_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU9192988.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFTAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(1717..3705)
                     /locus_tag="VWX69_001678"
     CDS             complement(1717..3705)
                     /locus_tag="VWX69_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9192989.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFTKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(3707..4465)
                     /locus_tag="VWX69_001679"
     CDS             complement(3707..4465)
                     /locus_tag="VWX69_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9192990.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4893..5084
                     /locus_tag="VWX69_001680"
     CDS             4893..5084
                     /locus_tag="VWX69_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192991.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(5438..5710)
                     /locus_tag="VWX69_001681"
     CDS             complement(5438..5710)
                     /locus_tag="VWX69_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9192992.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(5769..6218)
                     /locus_tag="VWX69_001682"
     CDS             complement(5769..6218)
                     /locus_tag="VWX69_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU9192993.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            complement(6205..8334)
                     /locus_tag="VWX69_001683"
     CDS             complement(6205..8334)
                     /locus_tag="VWX69_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU9192994.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            8378..8461
                     /locus_tag="VWX69_001684"
                     /pseudo
     CDS             8378..8461
                     /locus_tag="VWX69_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            8450..8590
                     /locus_tag="VWX69_001685"
     CDS             8450..8590
                     /locus_tag="VWX69_001685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9192995.1"
                     /translation="MDKTDEVSSKHCFEVVDRTDEVSSKHCFEVVDRTDEVSNRTTVR
                     RS"
     gene            8836..9741
                     /locus_tag="VWX69_001686"
     CDS             8836..9741
                     /locus_tag="VWX69_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU9192996.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            9738..10553
                     /locus_tag="VWX69_001687"
     CDS             9738..10553
                     /locus_tag="VWX69_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU9192997.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTNLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(10683..>11157)
                     /locus_tag="VWX69_001688"
     CDS             complement(10683..>11157)
                     /locus_tag="VWX69_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9192998.1"
                     /translation="LILLDGGYLDLDKILPLDTELEETKNYIKSQIISDLDVLTSKEK
                     SEAKHWSENMEKAVRQSYHWNVEYNRYELAINYENIEAILRLRRKIQAFKREVGDTLF
                     ISPRYPNEATWREEALKELPDYFDTIFLENFGHELYTQAPKEIASLMNEWLAYFL"
BASE COUNT         3341 a         2337 c         2154 g         3325 t
ORIGIN      
        1 ggcacagaga tgcaagacaa ttatactaca aaagccaaac atttgacaat cgatagccgt
       61 cgcttaatcg aaagatggaa aaaagaagga aaatcaaata gagaaattgc ctctctactt
      121 ggaaaagctc ctcaaactat ccacactgaa atcaagcgta ggacagtccg acaatgtctt
      181 ggaaaagggc gcttcaaaga ggtttattct gccgactatg ctcaacagtc ttatgaaaat
      241 aatcgcaagc actcggtcaa gagatcaagc gtgaccaagg aactaaagga aaagattctc
      301 cactatcata accaaaaatt ttcgcctgaa atgatggtta tggctaaagg ggttaacgtg
      361 ggaatttcaa ccatttacta ttggattcat catggaaaat tggggttaag caagcaggat
      421 ctgctttacc ctagaaaagg aaaagcgctt aagaaacagg ctagcaccaa ctttaaacct
      481 gctggtcaat ccatcgaaca gcggcctgaa gctatcaatc ttcgcttgga gaatgggcat
      541 tatgagattg atacggttct acttacgaga tcgaaaaact actgcttgct tgtcttgacg
      601 gatcgaaaga gtagacatca gatcatccga ttgattccaa ataaaagtgc tgaggtggtc
      661 aatcaggctc taaaactcat cttaaaacaa cacaagattc tttccatcac ggcagataat
      721 ggaacggaat tcaatcgctt gtttgatata ttttctgagg agcacatcta ttatgcgcac
      781 ccctatgcct cttgggaaag gggaactaat gagaatcaca acaggctcat tcgtagatag
      841 ttacctaagg gaaccaagaa aatgactccc aaagaagtcg cattcatcga aaagtggatt
      901 aacaactatc ctaaaaaatg cttggactac aagtcaccca gagaagactt ctggatggct
      961 aacttgaact tgaaatttag cgtcagaaac aaatcacgaa attgattcaa attttgcagg
     1021 tcgtttaaat atcctgcgtg cgggtgttct tgatgctaac gatggaatta tttccattgc
     1081 tggtgtggtt atcggagttg ccagtgccac gaccaatatc tggattatct ttttatcagg
     1141 ttttacggct atcttagctg gtgccttttc aatggctggt ggagaatatg tatccgtttc
     1201 aactccaaaa gataccgagg aagctgccgt ttcgcgagaa aaactcttgc tagaccaaga
     1261 tagggaacta gccaaaaaat ccctctatgc tgcttatatc caaaatggag aattcaaaac
     1321 ttctgcccaa ctcttgacca ataagatctt tcttaaaaat ccactcaagg ctctggtaga
     1381 ggaaaaatat gggattgagt atgaagaatt taccaatcct tggcacgctg ccatttctag
     1441 cttcgttgcc tttttcctta gaagtttgcc tccaatgctg tcagtgacca tttttccaag
     1501 tgattaccgc atccctgcta ccgtccttat tgtcggtgtg gcccttcttc tcactggtta
     1561 cacaagtgct agacttggaa aagccccaac caaaacagct atgattcgga accttgctat
     1621 tggtctcttg accatgggag ttaccttcct gctcgaacaa cttttcagca tttagaatac
     1681 aagaaatacc tcgattttga agtcgaggta tcttttttac atttgcacaa tcttgcgata
     1741 acttcttgaa gtaatcatga aaatcagcac ataggcgatg aggaagatag cgcagataga
     1801 caaggtcaca atcaacatca tagtcgtatc cagtacacca atcactttta aaatcaggct
     1861 aagcatatgg taggcaaagg cgagatgtat gaaggcaaag agcaaaggaa ggaagaaaac
     1921 agttaaaacc tgtttgttga tggtttgctt gatttgcttt tggtccaaac cgactttctg
     1981 caagataata aagcgttcac ggtcttcgta gccttcagaa atttgtttgt agtagatgac
     2041 cagaacagtt ccgaccataa agataatgga taggaaaata ccgataaaga agacaccacc
     2101 aaagagggca ctcatctgag aactagcatc tgctagattg ctaccataaa catagctacc
     2161 ttctgtgtct aattgagcat taaattgatt gaggtagttt tcatactcct cagcgacctt
     2221 gagttgttct tcttcgctgg catctacatt cataccaccg taaaactgat tatagatagc
     2281 cgaatctggg aattgatcca aaaaggcttg taaatcagga acaacaaggt aattgtaatc
     2341 agtagtcaag atattaaact tatttggaac atggttgaca ataaaatctt tagtaaattc
     2401 ttctttgaca gaaaattgat gatcatttag agttagagct ttctgtcctt tcagtccgtc
     2461 atttttggca aagagaccga cctcatttcc tgatagagac agtttttgac cagtcatatt
     2521 ttcataatct ttttggtcaa ataccatgaa aactgttttt ggttggacac ggttttgtcc
     2581 tttttcaaaa atagttaact tggttccttc ttgattcgca acagcaaagt aagtgtaacg
     2641 aaatacttct ttttctttaa tcttataacc tttgtcactt gcaaactggc tcaagagttt
     2701 gtccaagtct tctttttcaa cattttgccc tgaaacccca aaatcatgag gatttagaac
     2761 ttttttaaag ctttctgagg aattgaaaat gcttgtcgct gctgacatgg ttaccaaaac
     2821 cattgttgac aagatagcga tggtggctag tccaactgca tttttcttca tacggaaaat
     2881 caagttagaa acagatatga ggttatttgg ttggtaatag tatttcttat ttttctttaa
     2941 gatttggagg aaaacggtaa tccctgcatt aaacaagaga taagtcccaa agataaccag
     3001 taaaacagct atgaagaagg ttgttaaggc tgtaagagga tcttttaccg taagggcaag
     3061 ataatagcca attcctaaac ttatggaacc aagaatggtt tggagaggaa ggaagcgacc
     3121 ttttttctct ccactagctt tctcacgaga gagctggagg gcattcatac gggcgattcg
     3181 aagggcattc aggaacatga ggcctaggaa aatcaaaccg aagacaacaa gcactgtaat
     3241 gacaactttc gtctggaagg tagcaaccag ctcaaccttc aatttcatta gtttgagcag
     3301 gaaagcgaaa attaacttgt caaacaaggc tccaataccg atacccgctc caacagttag
     3361 aatcccaaat accactaact ccttaaaggt catactgata agatgacgct tctccaagcc
     3421 caacatgcca taaattccta gttccttgga acggttcttc atgacaaaac tattggcata
     3481 gagaacgata atggctgacg caagggtgac gacaaacata ccaaatccaa gtgtagcctg
     3541 aatggttgtt cctccacgga tttccgcaat cttaggattg aaggttagag agtaaaagag
     3601 ataggtgaca gtgactgcca agagaacagc cagcgcaaaa ggatagtaga gtttgcggtt
     3661 tttaatcaag ttcgataccg ctaacttatt ggttaatcga aacatactaa ttcacctcgc
     3721 ttgccatgac agtcaaggta tcagagattt cttggaacat ctgacgttct gtcttctctc
     3781 cacggtagat ttgattgtaa agaatgccgt ctttgataaa gagtacacgt ttagctctgc
     3841 tagctgctgc tgttgagtgg gttaccatga gaatggtttg gccgcgctca ttgatttcat
     3901 caaagacatc aagtaaggct gcagatgact tggagtcaag agctcctgtc ggttcgtccg
     3961 caaggagaat ttcaggttct gtgatgatgg cgcgggctac tgctacacgc tgtttctgac
     4021 caccagaaat ctcgtaaggg tacttctctt gtaattggtt tattcccaga ttctcagctg
     4081 tcaccaccaa tttcttcatc atctctgtaa taggtcttct tgacaagaca agcggaagca
     4141 agatattgtc ctttacagat agagtatcta gcaagttaaa gtcttggaag acaaagccca
     4201 acttttcacg acggaagcta gaggcctgtg aatttttaat ggttgcggtg tcagttccat
     4261 tcaagtaaac ctgaccacga cttggtttat ccagcatagc tagaatattg agaagagttg
     4321 atttaccaga accagactca cccatgatgg caacgtagtc acccttttcg acggtaaagt
     4381 gaatatcctt gagggcttct acttggttgc cctgaaaacg tgttttataa attttttgaa
     4441 cgtgttttac atctaaaagt gtcatgagaa tctcctttct taatatccca tcaaatgaaa
     4501 tgtagcttgc atcatagtgc atcccagctg aacgcgctca atttctttgt gacttggttt
     4561 tctagttttc ttatgtaaga tttgtttcat gatgttactc ctttgttctt tatgagtcta
     4621 gtttacatca aaaaaagacc gcttgccata acctaacctt acaaaagaga ctttaatctt
     4681 acatttttgt aagattgggt gaaatataag caaaattact tagaaaatga tttgatttcc
     4741 tatttttaaa gttgtaaaat ataagtgtga aaaggcttac tttgaaaagg aggaagcggg
     4801 aactaacatt ttagtaaggt tacctagata acataccatt caatttaaca cttgcaagtc
     4861 gttcaaccta taaggaaaga aggtgcgctt taatgaaaca caaagaacat atactcatcg
     4921 gacttctcta tctgctctct ccattcatcg gtcagctctt agttgaacac acacacttta
     4981 tcggtacaga atttaccggc actgcttatg ttatttgctg gttatcagtt gttatcagca
     5041 tccaccattt ttccaaaaat gtattgtctc agcagcaaaa atagattaaa aaactgagtt
     5101 taaattactg cttttataat aaaatgaaat aagaacagga caaatcgatc aggatagtca
     5161 aatcgatttc taacaatgtt ttagaagtag aggtgtccta ttctagttcc aatccactat
     5221 agtttgtgga tgaagctggc gaaatattat taatactatt caaaaatcaa agtgcaaact
     5281 atgtcaactt cacattgccg actaaattac agcctgtggc tggcttccta gtttgcactt
     5341 tgatttttat tgagtataaa agtaaaaaag ctttaaatca agcagtttag actattgatt
     5401 taaagctttt tgcttattcc aaatcttctg tagaacctca ccaaaaccag ccttcattgt
     5461 cgtcaatggc ttgggcttct ttgcgtttac gtgggcctgt tccgtacatt tctgcttcga
     5521 tttcttcctt ggtaggcatg atagaagcta ggatgatata gataatcacg ccaagtccaa
     5581 agtttgcaac tgtaaaaata gcaaacaaga aacgaactag ggtaacatca aaattccact
     5641 tgtctgacag acctgccaga actcctgaaa tcatgcgatt gcgtctcatt ttataaaatt
     5701 tactgttcat gatatttcct ctttctgcta ggttagacat agtatatcac ggggaggctc
     5761 ggctttcatc agtcctcagg ctgatttatc agaagcaatt tacctcgaca aagtccacag
     5821 cgatagcgtt tggtatcaat cctacgcttg cgctgatacc tttgctggca ggattgacaa
     5881 cgataaagct tgagtggttt agagttacta ttgggcaagg atggtacaaa ccgtaatcca
     5941 tccactgctt tcaaaagttc cttaaaatcc cgatccttgt gttgatagcc cttcccttgg
     6001 aaataaaggt gataatgaca gagttcatgt cggacaattt tcctaaaaac ctccataccc
     6061 agtttctgat aaaccttggg attaaaatcc agatgcccat ctttggggaa aaatcgccca
     6121 cctgtcgaac gtagacgcct attccactgg acatgatgga taaaagctct cccgaagtct
     6181 tctagtgaaa cctgcttgac ataatcagtc agtttcattt ggagcgagga gcgacagatt
     6241 aactttttca cgttcagtat caattttctt gacccaaacg gtcaccaaat ctccaactgc
     6301 caccacttga ctagggtgtt tgataaactt gcgactcata tgagaaatat gaatcaagcc
     6361 gtcctcgtga atcccgatat caacgaaggc accgaagtca acaacgttac gcacaacacc
     6421 ttctagcttc tgacctacca ctaggtcttt gatatctagg acatcttggc gaagcacagg
     6481 tgcgtcaaag gaatcacgga aatctcgacc tggtttgaga agatctgcaa tgatatcttt
     6541 aagggtttct ggaccgaggt ctagctcttg agccatttcc ttgactgaaa gcgacttgag
     6601 tttgctttgg gcctcttcat tcagatcctt aatgtccaag catttgaaga gttccttaac
     6661 ggcagcgtaa ttttctgggt gaactcctgt attatcaagg atattgctac tttcagggat
     6721 acggaggaaa ccagcagcct gttcaaaagc cttggccccc aaacgaggaa ctttcttgat
     6781 ttgggagcgt gaagtgattt ttccctcttc ctcacggtat ttgacgatat tttcagaaat
     6841 ggttttattg agtccagcta cgtgtgaaag aagagctggg ctagctgtat tgacattgac
     6901 accaacttgg ttaaccactg tatcgacaac aaagtccaga ctctcagata gtttcttctg
     6961 actgacatcg tgttggtatt gaccgacacc aattgactta ggatcgattt tgaccaattc
     7021 cgcaagagga tcttgcaaac gacgggcgat agaaatggca gagcgttttt caacggtcaa
     7081 gtctggaaac tcctgacgag caagttcgct ggcagaatag acagaagcac cactttcatt
     7141 aacgataaca tagctgactt cagggaaatc tttcagaact tccgctacaa aagcttcact
     7201 ttcacgactg gccgttccat ttccaatggc aataatctct acaccgtatt gaccaattaa
     7261 atctgctaaa tctttcttgg cttcttcgat ttgacgagct gatgctggtt taacaggata
     7321 aataacctga gttgtcagca tttttcctgt tgcatccacg acagctagct tggcacctgt
     7381 acgaaaggct gggtcaaacc caagaaccac gcgccctttc agtggagcaa ccaagaggag
     7441 attgcgcaga ttgtcagaaa aaagttggat agctccctct tcagctttct cagttaattc
     7501 tgtccgaata cgacgctcaa tagcaggcaa gacctttttc ttaacggatt gctgaacaac
     7561 ttcatcaata taagcatttt tcaccttgaa acgagtagca aagaaggcaa gaatacggtc
     7621 cgtcgcatgt tcaaaaccga tcttcaagac accaagtttc tccccacgat tgagagccaa
     7681 ggtacgatag ccttgcatag ttccaactgt ctctgaaaaa tcataataaa tctgaaaaac
     7741 ctgcttttca tcaagacttt catccttggc ttgagaagtg agtttagagt gtctcagcac
     7801 ttcctgataa gtcatagaac gcaaggtcac atcttccgat aaggcttcga ccaaaatatc
     7861 aactgcaccg gtcaaggctt ccttgccagt cgcaaatcct tcacagacga acttttcagc
     7921 ttctttctct aagtcaacta tattctgcaa aatcaaacga gcaagaggaa agagtccagc
     7981 ttcacgggca atggttgcct tggtacgacg cttttcctta taaggaagat agagttcttc
     8041 aacgtctgct aatttttcgg caactaagat agcttcttcc aattccttgg tcaacttacc
     8101 ttgttcttga atcttagcta agacagcttc cttacggtca ttgagatttg tcagactttt
     8161 atccaaatca ataatagcct taatcgccac ctcatccaga ctaccagtca tgtccttgcg
     8221 ataacgcgcg ataaagggaa tagtcgcccc ttcagctgtc aaacttagaa cggtatcaat
     8281 ttgctttaac gtcactccca aatcctgaga gattttttca tattttttat ccataaatct
     8341 attataccac aagctggaag gctttctcca atccttttca tactcaataa aaatcaaaaa
     8401 gcaaactagg aagctagccg taggctgctc aaaatactgt tttgaggttg tggataagac
     8461 tgacgaagtc agctcaaaac actgttttga ggttgtggat agaactgacg aagtcagctc
     8521 aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccgta ctacggtaag
     8581 gcgaagctga cgtggtttga agagattttc gaagagtatc aactatcgaa aacaaattaa
     8641 aaaactccct tttccgcaaa ataatagtat aatagaggta gaatttagaa tcgaggtaca
     8701 cctatggctg tcaaatttac aaaacgagac gacttggaca agatgtttga agagtttgct
     8761 aaactccctg atttgaaaca agttactttc cctgatgaca aagagaaaaa agtcaaagca
     8821 gaaaagaaaa actagatgac tgcttttcaa caactcccat ctagtgtact tcaaactgga
     8881 gccatttttc tctccattat cattgaagcc cttcccttcg ttctgatagg aagcattgtc
     8941 tcagggctga ttgaagttta tatcacacct gacaaggttt atcattttct ccctcgaaat
     9001 cgttggggga gaatcttttt tgggaccttt gtcggtatac ttttcccttc ttgtgaatgt
     9061 ggaatcgtcc ccatcatcaa tcgttttctg gaaaaaaagg ttccaagtta cacggccgtt
     9121 ccttttcttg tgacagcacc tgttatcaat cccattgttc tttttgcgac ctattctgcc
     9181 tttggcaact ccttccatgt cgccctatta cgagctctgg gttccattct tgtggctgta
     9241 atactaggaa tttttctagg atttttctgg caagaaccga ttcagaaaga aaatcgtctg
     9301 gcttgtcatg agcatgattt ttcttacttg agttctgcaa aaaaagtttt tcaagtcttt
     9361 gtgcaggcca ttgatgaatt ttttgatacg gggcgttatt tggtatttgg ctgcctcttt
     9421 gcttctataa tacaggtcta cgttccgact cggattctga cctctatcag tgcgacccct
     9481 ctttttgcca tcctgctctt gatgatttta gcctttcttc tttcgctctg tagtgaggcg
     9541 gatgccttta taggtgcttc tcttctctcg agtttcggtt tggcaccagt tctggccttt
     9601 ctcgtcattg gtccaatgct ggatatcaaa aatattctca tgatgaaaaa ttacttgaaa
     9661 gcacgattta tcagtcactt cataacaatt gtaactcttg tcgtcttagt ctattctctc
     9721 ttgattggag tcatcctatg attcgatttt tagttttagc tggctatttt gaactgacta
     9781 tttacctcca tctgtcgggc aaactaaacc agtacatcaa catgcactat tcctatctgg
     9841 cctatatctc catggtgctt tcttttatct tggctatcgt tcaattgtat atctggatga
     9901 agcaagtcaa aacccacagt catctgaaca gccgattggc caagatgacg agtatttctc
     9961 ttctggctat tccacttgtc atcggcttaa ctttcccaac tgttagcttg gattctcaga
    10021 ctgtttcagc taaaggctat catttccctc tatcggaagg aacgaatctg gctattcaga
    10081 caagtgaagg gactacaagc caatatttga aaccagatac tagttcttat ttttcaaaat
    10141 cagcctatga aaaggaaatg cgaacggcgg cggataaata cttatcccaa gacagcattc
    10201 agatcactaa tgaaaactat atggaagtca tggaggctat ctacgactat ccagatgagt
    10261 ttgagggcaa gacaatccag tttacaggct ttgtctataa cgaccccagt catgccaata
    10321 gtcaatttct gttccgattc ggcattatcc actgtatcgc agattctggt gtctatggat
    10381 tgctgaccaa gggcaatacc cggcagtatg aaaacaacac ttggatttca gccaaaggaa
    10441 aactggtcaa tcactaccat aaagaactca aacaaaacct tccaaccttg gaaatcgaca
    10501 gctttaccaa agtcgataaa ccagaaaatc cctatgtata tagagctttt taagaaaatc
    10561 aagataaaaa cgaacaagtt ctcttctgaa taacagaaaa agagcctgtt cgttttttgg
    10621 ttatatgaaa attagtgact tgtagatttt catcttatac catttccagc aatacaagta
    10681 gctcatagaa aataagcgag ccactcattc attagactag cgatttcttt aggtgcttga
    10741 gtataaagct catggccaaa gttttctaaa aaaatagtat caaaatagtc tggcaattct
    10801 tttagggctt cctctctcca tgtagcttca ttaggatagc gaggactaat aaacaaggta
    10861 tctcccactt ctctcttaaa agcttgtatt tttctccgta ggcggagtat cgcttctata
    10921 ttttcataat ttatagccaa ctcatatcta ttatactcaa cattccagtg ataggactgt
    10981 cttacagctt tctccatatt ttctgaccaa tgctttgctt cagatttttc tttagaagta
    11041 agaacatcta agtccgaaat aatttgagat ttgatataat ttttagtttc ctctaactct
    11101 gtatccaaag gtaaaatctt atctaaatct agatagccac catccaaaag aatcagt
//
LOCUS       DAVKBK010000060        11150 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVKBK010000060 DAVKBK010000000
VERSION     DAVKBK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.060"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..2314
                     /locus_tag="VWX69_001689"
     CDS             <1..2314
                     /locus_tag="VWX69_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEU9192999.1"
                     /translation="ETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLP
                     ALNSVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENN
                     NKVIDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSAL
                     DNVIELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFK
                     EQTKAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSV
                     FIIANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKN
                     KEKLYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYA
                     TGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPD
                     HPNDPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEG
                     KAVAKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHD
                     IITRRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKD
                     GMVPYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKE
                     REDKFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETN
                     SRVLKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            2358..7571
                     /locus_tag="VWX69_001690"
     CDS             2358..7571
                     /locus_tag="VWX69_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9193000.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            7825..8676
                     /gene="ylqF"
                     /locus_tag="VWX69_001691"
     CDS             7825..8676
                     /gene="ylqF"
                     /locus_tag="VWX69_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU9193001.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            8663..9442
                     /locus_tag="VWX69_001692"
     CDS             8663..9442
                     /locus_tag="VWX69_001692"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU9193002.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            9458..11008
                     /locus_tag="VWX69_001693"
     CDS             9458..11008
                     /locus_tag="VWX69_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU9193003.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         3860 a         1804 c         2246 g         3240 t
ORIGIN      
        1 agagacactt aatgtaaatt atcaaactga tttttcaaat gtagcagagt atagaatagg
       61 cggtacaaac ttaatttata caccgaatac attacttcgc aattatcaaa atattttaga
      121 tgaagtatta ccagcattaa atagtgtaga atataaatca gaggcaatta gaaaagtatt
      181 agatgtttct aaggatgtta gtttaacgga gttatattta gaagaacaat tcaataccac
      241 aaaaactaat ttgaaagata gtttgacaaa acttcttact gcagatgctg caatagctga
      301 aaataacaat aaggtaatag ataattatgt aatcgagaaa attaaaaata ataaagaagc
      361 tttacttcta ggattaacat acttagagcg ttggtacgac ttcaaatatc gtgatacaaa
      421 agcgaaagat ttagtcatgt accacttgga tttcttcggt aaatcaaata gttcagcgtt
      481 agataatgtt atcgaactag gtaaatcggg atataataac ttactagcaa aaaataatgt
      541 tataacttat aatgttttat tagcgaaaaa ttataagact aataatttat ttgatgcatt
      601 agagaaatat agaaaagcat ttgtaccaga taaaacaaat aatgagtggt ttaaagaaca
      661 aactaaagca tatattgtag aagaaaaatc tactattaaa gaggtaagtg ataagcaatc
      721 aatagctggt agtccatatt caattggagt atatgataga ttaactagcc catcttggaa
      781 atatccaagt atggtgttgc cgctattaac attacctgaa aaatcggtgt ttattatagc
      841 caacatttcg actataggtt tcggtgctta tgatagatat agaagtaaag aacatccagc
      901 aggaactgat ttaaatgact atgttgagaa aaaagctaaa gaagcggctg ttagatttag
      961 agatcactat gattattggt atagaatact agatgataaa aataaagaaa aattatatag
     1021 aagtgttcta gtctatgatg catttagatt tggtacagat gaaaaagaag ataaagatac
     1081 atatcaagca acttttgaaa ctaatcatcc agctataaaa catttcttcg gtccagcggg
     1141 aaataatgtt gttcataatt ctaatggagc atatgctaca ggggatgcat tctattatat
     1201 ggcatatcgc atgcttgata aagatggtgc ggtaacttat acacacgaaa tgacacataa
     1261 ctcagataga gaaatttatc ttggaggcta tggaagacga aatggacttg gaccagagtt
     1321 ttatgctaaa ggactgctac aagctcctga tcatcctaat gatccaacag tcactattaa
     1381 ttccatatta aaatatgatc aatcagaaga atcaacaagg cttcaagtag cagatccaac
     1441 tcaacgattt ggaagtgttg atgatctaaa taagtatatg cataatatgt ttgatgtaat
     1501 atacatgctt gaaatactag aaggtaaagc tgtagctaaa ttagatacaa atcaaaaata
     1561 tgatttatta agaaaaatag aaaatgaata taaacctgat cctgatggaa attctgttta
     1621 tgcaacgaat gttgtacgta gattaaaacc agaagaactt actaaattaa ctacatttaa
     1681 cagtttgata gaacatgata ttataacaag aagaggttat gtagatgaag caacttataa
     1741 gcggaatggc tactatacaa ttaatctatt ctcaccaatt tattcagcat tgagcagtaa
     1801 aataggaaca ccaggagatt taatgggacg acgtattgca tttgagttat tggcagccaa
     1861 ggggtacaaa gacggtatgg ttccatatat ttctaatcag tatgaaaaag aagcgaaagc
     1921 tcaaggaaaa gttattacat catatggtaa acaaataggt ttagttactg atgaaattgt
     1981 tctttcaaaa gtatttaata accagtataa ttcttggata gatttcaaga aagatatgta
     2041 taaagaaaga gaagataaat ttggaaagtt aaataaagtt agttttatcg atccaaacgg
     2101 ttcttgggct cgacaacaga aagtgactat tgataatatt aatagacttg aaaaaatgat
     2161 tgaagatgca gtaaaatttg atgctgagga tgaagttgcc aaattatatc ctgagacaaa
     2221 tagtagagtt cttaaactga aaaaagcaat ctttaaagct tatcttgacc aaaccggtga
     2281 ttttagaagt tcaatttttg agaataaaaa atagtgttta ctattaggaa ataaaaagtg
     2341 aaggtggagg attagaattg tcattattaa aaaaagataa attttccatt cggaaaataa
     2401 agggtattgt tggttcggta ttcttgggga gtcttttatt tgcaccgtca gttgttggtg
     2461 catcgactta tcattactta gattatagta gtttgacaca aactgaacgt gatcaactca
     2521 aacaaggtag acctgatgaa tccaaagagt catatgcttt ggattatgaa aaagacgcac
     2581 taccaaacac aggaagttct caatctatta tgactgcatt gggtttgtta gctatcggga
     2641 gtcttattgt gattatcaca aaagataata gaaataaaaa aatagctaca tttttgattg
     2701 taggggcgac aggtttagtt acactatcaa ctgcttcagc acttaatttg aatgctaaca
     2761 tccatgagtc tggacgtgat ggtgtgttgc aaatttctgg ttacagatat gttggttact
     2821 tggagcttga tgataaaact gtttcgtcgg tttctccagc atcaactgtt tcgccagttg
     2881 agcaacccaa agttgtaaca gagaaaggcg aaccggaagt tcatgagaag cctgactata
     2941 cgcaaccaat aggtgcaaac cttgttgagc ctgaagttca tgagaaacta gcatacactg
     3001 aaccagtagg gacaacagga gtagatgaaa atggaaactt gattgaacca cctgttaacg
     3061 acatcccaga atatactgag ccagtaggta caacaggagt ggatgaaaat ggaaacttga
     3121 ttgagccacc tgttagcgac attccagagt atactgaacc aatatctaca gtttcagaag
     3181 ttgcatcaga aagagaagag ttgccttctt tacataccga tattcggaca gagactattc
     3241 ctaaaaccac tatagaagaa tctgatccta gcaaatttat aggcgatgat tctgttagac
     3301 aagttggtga ggatggcgaa cgtcaaattg ttactagcta tgaagagtta catggcaaaa
     3361 aaatcagtga cccagttgaa acagtaacta ttttgaaaga aatgaagcct aaaattcttg
     3421 taaaaggtac caaagaaaaa cctaaagaaa aaacggctcc tgttttgacc ttagatagaa
     3481 caaatacaaa tgtattaaac cgatccgcaa ctctttctta tcatttagtt aatacagatg
     3541 gagtcacaat caataaaatt actgcgacaa ttaaagatgg aaatgaaatt gtcaaaacag
     3601 tagatttgac ttcagagcaa ttagataagc aggtagaaga tttaaaattc tacaaggact
     3661 ataagataga gaccactatg acctatgacc gtggcaaggg agaagaaact gcaacattag
     3721 aagagaaacc acttcgcttg gatttgaaaa aagttgaaat taaaaatatc gcatctacta
     3781 atttagtgaa ggtaaatgac gatggtactg aaacacctag tgattttatg actgaaaaac
     3841 cttcagatga agatgtgaag aaaatgtact taaaaattac tagtcgtgat aataaagtaa
     3901 cacgtttagc agttgataaa attgaagaag tgactgaaga aggtaagaaa ctttataaaa
     3961 tcactgccga agctcaagat ttgattcaac atacagaccc aacgaaggtt cgtaacaagt
     4021 atgttcatta tattgaaaaa ccagttccaa aagttgatga cgtttattat aactttaaag
     4081 agttagtaga tgccatgaat gctgataaaa atggtacatt taaaatcgga gcagatttga
     4141 atgcaacgaa tgtaccaaca cctaacaaac aatatgttcc aggtacgttt aagggacatc
     4201 tatcaagtgt tgatggtaaa caatatacaa ttcataacat tgcccgtccc ttatttgacc
     4261 gtgttgaaaa tggttctgtg aaaaatatta atttaggtaa tgtggatatc aatatgcctt
     4321 gggctgacgg aatagcacct gttgccaata tggtgaaaaa tgcaactgtt gaagatgtta
     4381 aggtaactgg taatgtagtt gctaataaca atattgcggg tatcgtcaat aaaatcgata
     4441 gtggtggtca gttgacaaat gtagccttca tcggtaatct tacaggtgtt ggtgataaag
     4501 gtcaatatat ggctggcatt gccggtgaga tttggagagg taatcttgca aaagcatatg
     4561 tcgaggctga tattgttgct aacagagccc gtataggtgg tttagttgct aaaacagata
     4621 atggtaacga ctctatggga attggtaaat acggttcaat tcgtaaatca gtcaccaaag
     4681 gaaccattaa gactaaagtt ttgtttgaaa caggtggatt tatcaatagc aatcttcctt
     4741 ttggtaaact tgaagataat atttcaatga tgagagttga aaatggtgaa gagttctttg
     4801 gttcttccga tttggactac gatggtggtt atttcacaaa tggctggtta gagcgtaact
     4861 ttgttgtcaa aggtgtcagt tcaggtaagc attcatacaa acgttctcgt gacaaaatta
     4921 aagaaattag tcaagatgaa gctaataaga gaattgcaaa ttttggactt actgctgata
     4981 aatacgaaat caacgaacct gtggtcaatc gcttaaatcg tttaaccaga agagaagatg
     5041 aatataagtc aactcaagac tacaaatccg aacgtgattt agcttatcgt aatattgaga
     5101 aacttcaacc attttataat aaagaatgga ttgtcaacca aggtaacaaa cttgcagaag
     5161 attcaaactt agctaagaaa gaagtccttt ctgttacggg gatgaaggat ggtcaattcg
     5221 tgaccgattt atcagatatt gataagatta tggttcacta tgctgatggt actaaggaag
     5281 aaatggatgt tactaagaat actgattcta aagtccaaca agtgcgtgaa tatagtgtat
     5341 ctggtcttgg tgatgttgtt tatacaccga atatggttgt taaaaatcgt gataaattga
     5401 ttgctgatgt taaatctcaa ttatcaagtg tggaattgat ttcacaagaa gtaagagatt
     5461 taatgagtag acgtgataaa cctgcagaga atacggatga acgtaagaat ggttatatta
     5521 aagatctata cttagaagaa agctttgccg aagtgaagca aaatctagat aagttagtca
     5581 aatccttggt cgaaaatgaa gaccatcaat tgaatggtga tgaagctgcg ataaaatcac
     5641 ttctcaagaa agtggaaacc aataaagcta aaatcatgat ggctctgact tatctcaatc
     5701 gttactatga tatcaaatac ggtgacataa gtataaaaaa catcatgatg ttcaaacctg
     5761 atttttatgg taaaacacca agtgttattg acagactcat caacatcggt tcaagtgaaa
     5821 agaacttgaa aggggatcgg actcaggatg cttaccgtga aatcatcgca ggtaatactg
     5881 gtaaaagtaa tttgcgtaac ttcttagaat acaacatgcg tctgtttaca gaggataaag
     5941 acatcaatga ttggtttatc cactcagcta agaatgttta tgtttcagaa cctaagacaa
     6001 caaatacaga gttgaaagat aaacgtcatc gtgtgttcga tggtttagat aacggtgttc
     6061 atggtcgtat gattttacca cttctaacgc ttaaagatgc ccatatgttc ttaatttcaa
     6121 catataacac gatggcgtac agttcatttg agaaatatgg aaaacataca gaagaagctc
     6181 gtaatgagtt caaaactaag attgatgaag ttgcacatgc tcaacaaact tatttagatt
     6241 tctggtccag attagctctg cctaatgttc gtgatagact tcttaagagt caaaatatgg
     6301 taccgacacc agtttgggat aaccagacct acaatggttc tcctgtaggt cgtcgaggat
     6361 ttgacagtaa aggtaaccct atagctccaa ttcgtgaatt atatggtcca acatggcgac
     6421 accatgatag agactggcgt atgggcgcta tggcatcaat attccctaat ccaaataatg
     6481 atgacaaggt cttgtttatg gtgacggata tgattagccc atttggtatt tcagccttta
     6541 ctcacgaaac aacacacgta aacgatagaa tgctttactt cggtggtcat aagcatcgtc
     6601 aaggtacaga cgttgaagcc tatgctcaag gtatgttgca aacacctgac agctcaacga
     6661 ctaatggtga atacggcgca cttggaatta acatggctta ccatcgtcca aatgatggta
     6721 accaatggta caacccagat cctgacaaat taaagacacg tgatgacatt gaccgctaca
     6781 tgagaaacta caatgaagct atgatgttgc ttgatcatgt agaagctgat gctgtacttc
     6841 ctaaaattaa aggagacaat agtaagtggt tcaagaagat tgacaaagaa atgcgctcta
     6901 agattcagta taatgatctt ttaggtccaa accaatggga tagtatccgt gatttgaaag
     6961 atgaagaaaa ggtaatgact ttatctagcg tcaatgattt agtggataat aacttcatga
     7021 caaaacatgg aaatccaggt aatggacgtt atagaccaga agattttaca ccaaactcag
     7081 cttacgtaaa tgtcaatatg atggcaggaa tttacggtgg gaatacgagt caaggtgctc
     7141 ctggttcatt atcatttaag cacaatgctt tccgtatgtg gggctattat ggttatgaaa
     7201 atggctttat tagttatgta tcaaataaat acaaagcaga agcagataaa aacaaccacg
     7261 gtttactaag cgataagcta ataattaata aagtatcgaa aggaaacttt aatactcttg
     7321 aagagtggaa gagacattgg tacggggaag ttcttgctaa agctaagaaa ggttttgagg
     7381 ctatcgatat tgatggcgtc catatcagta actatgatga gttaaggcct ttatttgata
     7441 aagcagttga agaagatttg aagaaaccag atgacttctc tcacactgtt gctcttaaat
     7501 ctaaggtctt caaagccctt cttaaaaaca cagacggttt ctttaataaa ctgtttaaag
     7561 aagacattta aatgtttaga atatagaagg aacagttttt tgctccctct gaaaagtcat
     7621 catttgatgg cttttttcta tatagggtac ttgaaaggct atcatcggac aaaataaaga
     7681 aggcatgata taatataagg tagatttcta tgccataaaa caaaaaactg tttgaacatc
     7741 attcatttga gaacccttta tgttcaaacg atagtaaaat aaaataggat ctctaaaccc
     7801 ttgctacgaa aggaaaaaaa ctcaatggct actattcaat ggtttcctgg tcacatgtct
     7861 aaagcgcgtc gacaggtgca ggaaaattta aaatttgttg attttgtaac gattttggtg
     7921 gatgcacgct tacctctatc tagtcaaaat cctatgttga ccaagattgt tggtgataaa
     7981 ccaaaactct tgattttaaa taaggcggat ttggctgatc cagcaatgac caaggaatgg
     8041 cgtcagtatt ttgaatcaca aggaatccaa actctggcta tcaactccaa ggagcaagtg
     8101 actgtaaaag ttgtaacaga tgcggccaag aagctcatgg ctgataagat tgctcgccag
     8161 aaagaacgtg ggattcagat tgaaaccttg cgtactatga ttatcgggat tccaaacgct
     8221 ggtaaatcaa ctctgatgaa ccgtttggct ggtaaaaaga ttgctgttgt tggaaacaag
     8281 ccaggggtca caaaaggtca acaatggctt aaaaccaata aagacctgga aatcttggat
     8341 acaccgggga ttctctggcc taagtttgag gatgaaactg ttgcacttaa gttggcattg
     8401 actggagcta tcaaggatca gttgcttcct atggatgagg ttaccatttt tggtatcaat
     8461 tatttcaaag aacattatcc agaaaagctg gctgaacgct tcaaacaaat gaaaattgaa
     8521 gaagaagcgc ctgtgattat tatggatatg acccgcgccc tcggtttccg tgatgactat
     8581 gaccgttttt acagtctctt cgtgaaggaa gtccgtgatg gcaaactcgg taactatacc
     8641 ttagatacat tggaagacct cgatggcaac gattaaagaa atcaaagaat tccttgtgac
     8701 agtcaaggag ttagaaagcc ctattttttt agagcttgaa aaggataatc gctcaggagt
     8761 tcaaaaggaa atcagcaagc gtaaaagagc cattcaagct gaattagatg aaaatttgcg
     8821 cttggaatcc atgctttctt atgaaaaaga actttataag caaggattga ccttaattgt
     8881 aggtattgat gaggttggtc gtggtcctct tgctggtcct gtagtcgctg cggccgtcat
     8941 tttacctaaa aattgtaaga ttaaaggtct caacgacagc aagaaaattc ctaaaaagaa
     9001 acatctggag attttccaag ccgttcaaga ccaagccttg tcgattggaa ttggtatcat
     9061 agataatcag gtcatcgacc aagtcaacat ctatgaagca accaaactag ccatgcaaga
     9121 agcaatctcc cagctcagcc ctcaaccaga gcaccttttg attgatgcca tgaaactgga
     9181 cttgcccatt tcacaaacct ccattatcaa aggagatgcc aactccctct ctatcgcagc
     9241 agcatctata gtagccaagg taacacgtga tgaattgatg aaggaatacg atcagcagtt
     9301 ccctggctat gatttcgcta ctaatgcagg atatggcaca gctaaacatc tggaaggcct
     9361 cacaaaacta ggagttaccc caattcaccg aaccagcttt gaacccgtta aatcactggt
     9421 tttaggtaaa aaagaaagtt aattgaaagg aaataccatg gaggaacagt cggaaatagt
     9481 ccgttctaag aaagaattcg cctttgcatc cagcactata ctatcccaag ttggtcgagg
     9541 aatcattgtc ggcctcatcg ttggaattat cgtcggatcc tttcgtttct taattgaaaa
     9601 gggcttccac ctgatacaag gagtttatca agatcaaggg tacttagtgc gcaatctttt
     9661 tgtactggtt ttgttttata tactcatctg ttggctcagt gccaaactaa cacggtcaga
     9721 aaaagatatt aaaggctcag gaattcctca agtcgaagcc gaactgaaag gcctcatgtc
     9781 cctcaactgg tggggcattc tttggaaaaa atatgtgcta ggtattcttg ctattgccag
     9841 tggactcatg ctgggtcgag agggacccag tattcaactt ggagcagttg gtggtaaagg
     9901 aattgccaag tggctcaaat ccagtccagt agaggaacgt tccttgattg ccagtggagc
     9961 tgcagcaggt ttagccgcag cctttaatgc tcctattgca gcacttctct ttgttgtaga
    10021 agaagtctat caccattttt cgcgcttttt ctgggtctca actctagcag ccagcatcgt
    10081 agcaaacttt gtgtctctac tcatgttcgg tttgacacca gtattggata tgccagataa
    10141 cattcctccc atgaccctag atcagtattg gatatatctc gtcatgggaa ttttccttgg
    10201 attttcaggt tttctctatg agaaagctgt attaaacgtt ggaagagttt atgacttgat
    10261 tggtcaaaaa atccatttgg atagggctta ttatcccatc ttggctttta tccttatcat
    10321 accagtcgga atcttcttac ctcaaatcat tggtggcgga aatcagcttg tcctttcttt
    10381 aactgaacaa aattttagtt tccaagtttt attagcttac tttttaatcc gctttatttg
    10441 gagtatgatt agctatggaa gtggactgcc aggaggaatt ttcctcccca ttttagctct
    10501 tggttctttg cttggtgcct tagttggtgt tatctgtgtc aatcttggac ttgtcagtca
    10561 agagcaattc cctatatttg tcattctagg aatgagtggc tattttggag ccatatcaaa
    10621 agctccctta accgctatga tcctcgtaac tgagatggta ggagatattc gcaaccttat
    10681 gccacttggt cttgtcactc ttgtttctta tattatcatg gatttgctca aaggtacgcc
    10741 agtctatgaa gccatgctgg aaaaaatgct tccagaagaa gtatctagcg aaggagaagt
    10801 tacacttatc gaaataccag tttctgataa aattgctggg aaacaagttc atgaactcaa
    10861 cttaccacac aacgtcctca tcacaactca agtccataat ggcaagagcc aaacagttaa
    10921 cggctcaacc agaatgtatc tgggtgatat gattcacctg gttattccaa aaagtgaaat
    10981 tggaaaagtc aaagatttgt tgttgtagta tgatcattta cataatttat gttatgtaaa
    11041 tgatcagttt gatttattta gaaaaccgat tctcagaaat gagatcggtt attttttact
    11101 gatgaggaat tttacatata aataattgaa ctttattaaa aataagacta
//
LOCUS       DAVKBK010000061        11012 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVKBK010000061 DAVKBK010000000
VERSION     DAVKBK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.061"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(284..1090)
                     /gene="yidA"
                     /locus_tag="VWX69_001694"
     CDS             complement(284..1090)
                     /gene="yidA"
                     /locus_tag="VWX69_001694"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU9193004.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1103..2407)
                     /locus_tag="VWX69_001695"
     CDS             complement(1103..2407)
                     /locus_tag="VWX69_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU9193005.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2479..2856
                     /locus_tag="VWX69_001696"
     CDS             2479..2856
                     /locus_tag="VWX69_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU9193006.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2947..3279
                     /locus_tag="VWX69_001697"
     CDS             2947..3279
                     /locus_tag="VWX69_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU9193007.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            3291..4862
                     /gene="ffh"
                     /locus_tag="VWX69_001698"
     CDS             3291..4862
                     /gene="ffh"
                     /locus_tag="VWX69_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU9193008.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5057..6340)
                     /locus_tag="VWX69_001699"
     CDS             complement(5057..6340)
                     /locus_tag="VWX69_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU9193009.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6643..7356)
                     /gene="rsmG"
                     /locus_tag="VWX69_001700"
     CDS             complement(6643..7356)
                     /gene="rsmG"
                     /locus_tag="VWX69_001700"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU9193010.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7450..8010
                     /locus_tag="VWX69_001701"
     CDS             7450..8010
                     /locus_tag="VWX69_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU9193011.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            8012..8911
                     /gene="htpX"
                     /locus_tag="VWX69_001702"
     CDS             8012..8911
                     /gene="htpX"
                     /locus_tag="VWX69_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU9193012.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(9060..10619)
                     /locus_tag="VWX69_001703"
     CDS             complement(9060..10619)
                     /locus_tag="VWX69_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9193013.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(10901..>11012)
                     /locus_tag="VWX69_001704"
     CDS             complement(10901..>11012)
                     /locus_tag="VWX69_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9193014.1"
                     /translation="TKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT         3212 a         2044 c         2458 g         3298 t
ORIGIN      
        1 tgaagtatcc taatttgtat aattgattgt gtgtagattc agggtcaatt tgaagagagt
       61 atttaaaata tcttgggaaa ttataatttc tccctgtttt ttgagtccaa tctatgagta
      121 tgagttgccc aggagtaagg ccacattcta aatcgtttag gtaaaaattg ttacaatcag
      181 aatttgtgtc tctattatga ttattttgtt ttaaattaaa tagtttgcta aaaaaattca
      241 ttggatttta ttgctaatca attcttattg aaaaatgata cttttacagt acccatgttc
      301 ggatggcgtg ggcaacgccg gattcgtcat ttgttttagt gatgtatttg gcgatttttt
      361 tgatttctgg atttccattt tccatgacaa cggggtttcc aacgacttcc agcatggcac
      421 ggtcattttc ttcgtcaccg attgccatgg tttcatcttt ggtcaatccg agtttttcag
      481 ccaagtgagt aatagctgaa cccttgtcta cattcttttt aaggagttcg aggtagaaag
      541 gagcagattt gttgatagag tagtgctcgt aaaattcggc tggtattttt tcaatcgcag
      601 catcgagaat ttctggttca tcgatgaaca tacacttgac aatttccttg ccagccattt
      661 cttcaggggt acggtagaag ataggcatgc tgacgagggt tgattcgtgt acagtgtatg
      721 ttccgatatt gcgatttgca gtatagatac cgtccttggt aatggcatgc atgtggacac
      781 cgagcttgcg actgaggaat tccatatcca gataatcctc ataggtcaag gattcgctga
      841 taatctcatg gccagtagca gtttcttgga caagggcacc attgaaggtc accacatagt
      901 caccttggtc tctcaactgc aagtcgtcca gaagtttggc aacacctgcg atggggcggc
      961 cagttgcaat cacgactttg acaccagctt ctttggcatc ttggatggca gaaaagactt
     1021 caggagtgat ttccttttgg ctgttgacta gggttccgtc aatatcgacg gcgattagtt
     1081 taatactcat aaatttcctc ttttagtttt tatttggggt aaaatgatcg ttctcaatca
     1141 agtgtaaaaa ttgctgggtg atgcttgcga agatgctgtt ttggtctaac atttctttcg
     1201 ggaaataaaa gcgattatct ccgtggcgac ttccagcaag ggattggacg ataggggaca
     1261 ggctagagag ttctgccagt tctccatttt tttgtaaaat ctcaatctgt gtccttggat
     1321 tttcagattc gggacggtaa atatcataag ggaggtcaaa gttcttatga atggcagtat
     1381 agtagtcggg atcaaagccg atgtcctcaa ccaattttct catgctagcg agttggtctt
     1441 ggtcttcttg tgaaaaggta atggatttaa agaccttgcg gttgacaaag cgatgcgata
     1501 aatctgcaag aatcttgtca ggactggtca tccaaagctg gaagtaggta ttcatcacgc
     1561 catcatccag agccagatag tcagtcaagg tcacattttt ttcgaagaaa ggcaggaggt
     1621 gtggagaagt tcgggcaaag aaatccttgt cctcaggata gagttccttg gcgcgtttga
     1681 gaagattctg taggagaact tccatggcgc gtgttgcggg gtggaaataa acctgcatgt
     1741 acatctggta gcgactgagg acgtagtctt cgatggcgtg catgccattg cgctgaaagg
     1801 cgataccatt ttcgatagga cgaatgactc ggaggattcg agtcaggtca aattccccat
     1861 aggatgctcc tgtaaaatag gagtcgcgca agagatagtc catgcgatct gcgtcaatct
     1921 gactagaaat gagctgcacg acctgcttat taggataggt atggtcaatg acactggcca
     1981 ccttttctgg gaaatcaggt gccacttgta gcaggacttg gtgaatctct gtctcaggat
     2041 tttgaataat ctcctgagta atggcttcat ggtctgtatc aaagagattt tcaaaagtat
     2101 gggagtaggc accatgccca aggtcgtgta ggagagcagc ggtcatggtc aagagagact
     2161 cggcaggatt ccattcctca ggatattttt cttcgaaaat ctctgtgatg cgtcgtgcaa
     2221 tttcatagac tcctagacag tgagagaagc gactgtgttc tccaccgtgg aaggtataac
     2281 tggaagttcc cagttgtttg atccggcgca aacgctgaaa ttcttttgta ttaatcaagt
     2341 catagatgat ttgattattg acatggatgt agttgtgaac agggtcacgg aatacttttt
     2401 cgttcatatg accattatag caaaatcctg ctctttttgg taaaatagta ggacaagaga
     2461 caagaaagag ggcctgatgt gaagattcgg atgcgaaata caattcagtt tgatgagcag
     2521 ttggaagtga ttgaccagct ttatgatgtg gaagtgcatg aaaaaggaga ttatagctac
     2581 ctgcttttct ataatgagga aaaggaaaaa gtagtgatta aatttcatgg tcaagaactt
     2641 gtgatgagtc gattttccaa tcccaagacc attatgcgct ttctaaagga tagtgatagt
     2701 ttagcctata ttcccacacc tatgggtatg caggagttta ttatccaaac gaatcgttat
     2761 caagtggatg ggcaaaagat tgaactagat tatcaactac aaaatcaaga gggacatccc
     2821 tttgccagct atcaattgga aattacttgg ggctaggctt atgtcttttt caaatttagc
     2881 tatctatctt cttggatcgg cttcctagtg tggtagatta ggctaatttt tggtataata
     2941 aaagttatgg aaatcgaaaa aaccaatcgt atgaatgcgc tctttgaatt ttatgcggcg
     3001 cttttgacag ataagcaaat gaattatatc gagctctact acgctgatga ttacagcctt
     3061 gctgaaattg ccgaggagtt cggtgtcagt cgtcaggctg tctatgacaa tatcaagcga
     3121 acagaaaaga ttctggaaga ttatgagatg aaattgcaca tgtactcgga ctatattgtc
     3181 cgcagtcaga tttttgatca gattttggag cgctatccca aggataactt tctgcaggag
     3241 cagatagaaa ttttaacaag cattgataat agagaataag aggaagaaaa atggcatttg
     3301 aaagtttaac agaacgtttg cagaacgtct ttaaaagtct acgtaaaaaa ggaaaaatct
     3361 ctgaatctga tgtccaagag gcaaccaaag aaattcgctt ggccttgctt gaggccgacg
     3421 ttgctttgcc tgttgtaaag gactttatca agaaagttcg tgagcgtgca gtcgggcatg
     3481 aggtcattga tacacttaat cctgcgcaac agattattaa aatcgttgat gaggaactga
     3541 cagccgtttt aggttctgat acggcagaaa ttatcaagtc acctaagatt ccaaccatca
     3601 tcatgatggt tggtttacaa ggggctggta aaacaacctt tgctggtaaa ttggccaaca
     3661 aactcaagaa agaagaaaat gctcgtcctt tgatgattgc ggcggatatt tatcgtccag
     3721 ctgccattga ccagcttaag actttgggac aacagattga tgtgcctgtc tttgcacttg
     3781 gaacagaagt accagctgtt gagattgtac gtcaaggttt ggagcaagcc caaactaatc
     3841 ataacgacta tgtcttgatt gatactgcgg gtcgtttgca aattgatgag ctcctcatga
     3901 atgagcttcg tgatgtgaaa gcattggctc aaccaaatga aattctcctc gtcgttgatg
     3961 ccatgattgg tcaggaagca gccaatgttg cgcgtgagtt taatgctcag ttggaagtga
     4021 ctggggtcat ccttaccaag attgatggcg atactcgtgg tggtgcggct ctatcggttc
     4081 gtcacatcac tggaaaacca atcaagttca ctggtacagg tgaaaaaatt acagatatcg
     4141 aaaccttcca cccagaccgt atgtctagcc gtatccttgg catgggggat atgctcactt
     4201 tgattgagaa agcttctcag gaatacgatg aacaaaaagc ccttgaaatg gctgagaaga
     4261 tgcgcgaaaa cacctttgat tttaatgatt tcatcgatca attagatcag gtgcaaaata
     4321 tggggccgat ggaagacttg ctcaagatga ttccaggtat ggccaacaat ccagcacttc
     4381 aaaacatgaa ggtggatgaa cgccagattg ctcgtaaacg tgccattgtg tcttcgatga
     4441 cacctgaaga acgtgaaaac ccagatttgt taaatccaag ccgtcgccgt cgtattgctg
     4501 ctggttctgg aaatacattc gtcgaagtca ataaatttat caaggacttt aaccaggcta
     4561 aacagctcat gcagggtgtt atgtctgggg atatgaataa aatgatgaag caaatgggga
     4621 ttaatccaaa taaccttcct aaaaatatgc caaatatggg aggaatggat atgtctgccc
     4681 ttgaaggaat gatgggacaa ggcggtatgc ctgacttatc agctctcgga ggagcaggaa
     4741 tgccagatat gagccagatg tttggtggcg gtttgaaagg taaaattggt gaatttgcca
     4801 tgaaacagtc catgaaacgt atggctaaca aaatgaagaa agcgaagaag aaacgcaagt
     4861 aagacaagag attgatgcaa atctcatttg atgagaaaat aaagtaaaaa tttctatgat
     4921 aaaacgtaca gtatcaaggt tttagaatat ctgatattat acgttttttg attttaataa
     4981 ttttgttaag acacttttat tatgatatac gaaaaatcca ctcagctgtc tgagtggatt
     5041 aggtgtattt agactcttag tctttatttt cgtatggcaa gatcaagttc aagatgattc
     5101 ctgtcatggc tgaaagggca gtacctgaaa gtgtaactgg accaagttta aggatagctc
     5161 ctccaagtcc aagaaccaac atagcacttg cgatgatgag gtttcgcatt tgagcgaaat
     5221 caacacgttc tttaatcaag actttcaaac cattgctggc gataacccca tagagaagga
     5281 ttgacatacc accaagtaca gcgtttggaa tagttgaaat caaggcagtg aatttaccaa
     5341 ggaagctgag ggcaatcgcg atgaaggcag cgttacggat aactgagaca gaagcgatac
     5401 gagtcatacc gataacccct gtattttctc cgtaagttgt attggctggt ccaccaagga
     5461 aggcagaaac agaagttgcg ataccgtcac caataagagt acggtgaaga cctggttctt
     5521 ttaagaattg acggccacag atttgaccca aaacagtatg gtctccgata tgttcagaaa
     5581 ttgttacgat agcgattggc aagatagcga tggcttctgg accaaagtaa agattgtact
     5641 ctttaaaggc accacctgtg ctaaatggca agtagaaacc aggaatttcg aaccagttgg
     5701 ctttaagaac tggtgtaaag tcaaccaagc caagagttag tgcgaaaagg taaccaccga
     5761 taatggcaaa gaggaatgga atgattcgta ggaagccttt tccttttgta ttgataaagg
     5821 cagcaattag gaaagtaaca acggctacca gagcattttt ccaatttccg tctgctacaa
     5881 gacctgcatt ggtaacagct gaacctgcaa gtccaagacc gataacgatg atcataggac
     5941 cgataatgat tggtggcaag agtttatcaa tccattttgt tcctacaaat cggatgctgg
     6001 tagcaacaag gacatagacc aaaccagtca agataacccc tgtttgggca gcagatacat
     6061 ccccccccat ttctttcata gccagtgaca tagctgtgat aaaggcaaat gaagaaccta
     6121 gataaactgg aactttaaaa ccagtagcaa tcatgtagat gagtgttcca acacctgaag
     6181 caaaaagggc aacagataca ggcattccca aaatcaatgg taccaagatg gtcgcaccaa
     6241 acatggcgaa aacgtgttgg aagctaagga gaattccttt tccatccgaa ggacgttggt
     6301 caacgtctag taacaaatca acagttgatt cttgtttcat ataaacctca cttttgggca
     6361 tcagaaaaga gcccattatt ttacagcaat aggccctcag agtaagactt ctctaaaatc
     6421 tagactttaa agagtttcaa atatttctgc gtcttcgtca cctcacggga tgacattaaa
     6481 aacctttgct taggatagta tagcagaaaa aaatgatttt gtaaatcatt ttttcccgag
     6541 cctagaaata aaagagcgag gctgattttg taaatcattt tttcccgagc ctagaaataa
     6601 aagagcgagg ctgattttgt aaacatttgt ttactaaaaa atttaaagtg ggcgtttatt
     6661 tggcatacca gccttacgtg gatatttatt tggtgtttct tttttctttt ctaccactgt
     6721 gatatagcgc ggatctctat tcggtagggc gtagctgaga ttgtcttcga ccttactaaa
     6781 aaggagattg agggcattct tagcttctaa caactcctca ggcgcattgc tagccttgag
     6841 tgctaatagt ttgccaccaa ccttaaggta gggaatagtc aattcagata ggacctgcat
     6901 acgggcaacc gcacgagctg ttacaaaatc atattgagca cggaagttct tgtcttgggc
     6961 aaaatcttcg gcacgtccgt ggtagaaatg aactccgttc aaatccagtt cttgagccaa
     7021 gagttgtagg aagttgatgc gcttattgag tgaatcaata atggtcacat ctaactccgg
     7081 atagagaatt ttcattggta gactaggaaa tcctgcccca gccccgatat caagaagttt
     7141 gatagtttca ttgggaatca aaccttgaag aatgggtgca atcgaatcgt aaaaatgttt
     7201 gagataaact tcttccttgt ccgtaatcgc cgtcaaatta atcttctcat tccactcgac
     7261 caagagctca aaataacgtt caaattgttc tttttgctgg tccgaaagtg gaagattctg
     7321 ctcggcaagc aagttgtaaa atgtttctgg tttcatagtt atttccttct ttagtatcat
     7381 cttattttac cacaatcatt aaaaatttga tatactggta ctaatctaaa agtagaaagg
     7441 acttatatca tgacttggat tattcttgga gttatcgctc ttattgttat ttttgtgatt
     7501 gttagctata acggtttggt taaaaatcgt atgcaaacca aggaggcttg gagtcagatt
     7561 gatgttcagt tgaaacgtcg aaatgacctc ttgccaaact tgattgagac tgtaaaaggt
     7621 tatgccaaat atgaaggttc tacccttgaa aaggtggcag aactacgtaa ccaagtggcg
     7681 gcagcgactt caccagcaga agctatgaaa gccagtgatg ccctcactcg tcaagtttca
     7741 ggtatttttg cagttgcaga aagctatcca gatttgaaag ctagtgctaa ctttgttaaa
     7801 ttgcaagagg agttgacaaa cacagaaaat aaaatttctt actctcgtca actctataac
     7861 agtgttgtca gcaactacaa tgtaaaatta gaaactttcc cgagcaatat tatcgctgga
     7921 atgtttggat ttaaagcggc agatttcctt caaacacctg aagaggaaaa gtcggttcct
     7981 aaagttgatt ttagcggttt aggtgactaa gatgttgttt gatcaaattg caagcaataa
     8041 acgaaaaacc tggattttgt tgctggtatt tttcctactc ttagctcttg ttggttatgc
     8101 ggttggttat ctctttataa gatctggact tggtggtttg gttatcgcac tgattatcgg
     8161 ctttatctac gctttgtcta tgatttttca atcgacagag attgtcatgt ccatgaatgg
     8221 agcgcgtgag gtggatgagc aaacggcacc agacctctac catgtagtgg aagatatggc
     8281 tctggtcgct cagattccta tgccccgtgt tttcatcatt gatgatccag ccttaaatgc
     8341 ctttgcgaca ggttctaatc ctcaaaatgc ggctgttgct gcgacttcag gtctactagc
     8401 tatcatgaat cgtgaagaac tagaagctgt tatgggacat gaagtcagtc atattcgtaa
     8461 ttatgatatc cgtatttcga ctattgcagt tgcccttgct agtgctatca ccatgctttc
     8521 tagtatggca ggtcgtatga tgtggtgggg tggagcaggt cgcagacgaa gtgatgatga
     8581 ccgagatgga aatggtcttg aaatcattat gctagtggtt tccctactag ctattgtact
     8641 ggcacctctc gctgcaacct tggttcagct cgctatttct cgtcagaggg aatttctggc
     8701 agatgcatct agtgtcgagc tgactcgcaa tccccaggga atgattaatg ccctagataa
     8761 gttggacaat agcaaaccta tgagtcgcca cgtcgatgat gctagcagtg ccctttatat
     8821 caatgatccc aagaaaggtg gggggttcca aaaactcttt tatacccacc cacctatctc
     8881 agaacggatt gaacgtttaa aacatatgta aaatgaaggc tggaaaaaag tctttaaaat
     8941 ctgaaaaacg cataatatca ggtgtgaaaa cttgatatta tgcgttttac tatgggaaga
     9001 tttacttctt tttctcctaa aattgtgttt ttgccccacc tatctgctat gttgcaaatt
     9061 tataaatctt ctaaattaac tagcttcaaa ccgtgttctg tcatgcgata gatgatcgag
     9121 cagacttctt ttaagaaacg acggtcatgc gaaacagtga tgagaccgcc aggataagtg
     9181 gcaaagagtt ttctgatttg gggttgagaa gtgggagaaa agtttcgtgt gggttcatcc
     9241 agcaggagaa agtttggttt gcgcaggact aaatccaaaa gcaggagttt tccctgttgt
     9301 ccgccagata aggagcgaat ttgatgctgc atttctggat aactgaaatt gagactagct
     9361 aggtgagatt ggattttctg tagttcctct ttttccccag ttttactgag ataggctatt
     9421 ggggataaat ccaattgcag ttttttgtgg taatcttgtg gcataaaacc aagtgaaatc
     9481 tctcttttat cattcagaag tctctgtaac ttggctaaca gagttgattt cccaacacca
     9541 tttggcccga taataccgat tttttcttgg ccacggacag ttagttgtag tttttgaacc
     9601 aaaactcggt cgtcaatgga caaattttct ttttccagtt ggactaagac tttagaagct
     9661 ggtaatggtt ggatgtctga aaagaaaagt tggatttgtt cctcttcaag tggtttttga
     9721 gtcatggact gagctgcctt ttcgtagcgt ttttcttgtg agaggacagt tttcatcttt
     9781 ttagccaata ggcgaccggc agtactatct ttggtagctc gaagcgcagt ttctacattt
     9841 tgcttaactc tccgatgttt ttccatggtt ttatcgtagg ctctttggtt gttagcagct
     9901 tgctgacttt gtttggcaaa attagccttt ctctgctcac tatagctatc atagtctaaa
     9961 tgctctacta gcgtttccgc ttctttacgg tgtttgacca gtcgcaagtg aacaatagtg
    10021 tctgccgttt cagaaagaaa gtcttcatca tgggaaatga aaataacggt ttgcctggtc
    10081 ttttgaatct ggccttttag ccaatcaact gtctcaaggt ctaggtcatt tgaaggttca
    10141 tctaaaaata gaatctcaaa gggtttggct aactcatgga taagctgaat tttcaaagct
    10201 tctccccctg atagattgcc aatctcttgg tcacttgcga aacgattgct atcaaaatgc
    10261 aattcctccg ccaaacgata gaggatactg tagtctaaat caatagaatc taaaaagaag
    10321 tagtcgtgta aagttttctt tttcagctcc tcgggaagtt tttgaggaat gtaggccagt
    10381 gactgatagt cagattggat gtctcccttg atagtgaaat cagacaaatc ttcccccatt
    10441 aaagttttaa gtaaggttga tttaccattt ccttcttcgc caataatagc taccttttcc
    10501 ccgtcttgta tggtcatgct taggtcagag acaaggtctc gtaaatcttt gttttgtgtg
    10561 atggtcaggt gattgatttt tatcatacta ttgccctttc tagaatgtcg atagtgcata
    10621 acaaaaagct ctactttacc tagtagagcc caaagtctat gtcaaaaaaa ctctattaac
    10681 atgccagaaa aagagcataa aagagcacac aaaaagagac aaaaacaaga tctactaaat
    10741 aaaggttctt tatttgatag acttagttgt tcatgtctcc cttacctccg agtattagta
    10801 tctttatatt atacctttaa ggaaattttg tcaacagaaa actggaaatt ctatgctcta
    10861 aaatccaaaa acaggtccat acccaaattt caagttgaag ttagccaccc aaaagaaatt
    10921 cacttggcga cttgtagtcc aagcattttt tagggtagtt gttaatccaa ttttcgataa
    10981 aagctacttc tttcggagtc gttttcttgg tt
//
LOCUS       DAVKBK010000062        10426 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVKBK010000062 DAVKBK010000000
VERSION     DAVKBK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.062"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(114..1328)
                     /locus_tag="VWX69_001705"
     CDS             complement(114..1328)
                     /locus_tag="VWX69_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9193015.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1484..1778)
                     /locus_tag="VWX69_001706"
                     /pseudo
     CDS             complement(1484..1778)
                     /locus_tag="VWX69_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1940..2392
                     /locus_tag="VWX69_001707"
     CDS             1940..2392
                     /locus_tag="VWX69_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU9193016.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2427..3815)
                     /locus_tag="VWX69_001708"
     CDS             complement(2427..3815)
                     /locus_tag="VWX69_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9193017.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3881..4843
                     /locus_tag="VWX69_001709"
     CDS             3881..4843
                     /locus_tag="VWX69_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU9193018.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(5049..6059)
                     /gene="ccpA"
                     /locus_tag="VWX69_001710"
     CDS             complement(5049..6059)
                     /gene="ccpA"
                     /locus_tag="VWX69_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU9193019.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLVKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6483..7082)
                     /locus_tag="VWX69_001711"
     CDS             complement(6483..7082)
                     /locus_tag="VWX69_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9193020.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLAFQADVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7083..8180)
                     /locus_tag="VWX69_001712"
     CDS             complement(7083..8180)
                     /locus_tag="VWX69_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9193021.1"
                     /translation="MLERLKSIDYMYWASLIFMIFPILPVVTGEIPSWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERAEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVSPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8180..8917)
                     /locus_tag="VWX69_001713"
     CDS             complement(8180..8917)
                     /locus_tag="VWX69_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9193022.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHTPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHFVRGVDMPLGSWIGAAFLLIVGSVAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYILVFSAVLFGLTIYLQGHKENA"
     gene            complement(8919..9803)
                     /locus_tag="VWX69_001714"
     CDS             complement(8919..9803)
                     /locus_tag="VWX69_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9193023.1"
                     /translation="MNMIKVESLNKNIKGKAILKGISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELIAFFQRIY
                     PNSLSDQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(9790..9984)
                     /locus_tag="VWX69_001715"
     CDS             complement(9790..9984)
                     /locus_tag="VWX69_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193024.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(9981..10112)
                     /locus_tag="VWX69_001716"
     CDS             complement(9981..10112)
                     /locus_tag="VWX69_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine aminotransferase"
                     /protein_id="HEU9193025.1"
                     /translation="MFSGLDESFYHFPWELFAGFGMMSWLVREGLKLVGDVKKEFEE"
BASE COUNT         3160 a         2402 c         1899 g         2965 t
ORIGIN      
        1 agcttttatc gaaaattgga ttaacaacta ccctaaaaaa tgcttggact acaagtcgcc
       61 aagtgaattt cttttgggtg gctaacttca acttgaaatt tgggatgcaa gccctatcta
      121 cgatactgtt tcaagaaacg agtcatcttt tcttggattt gggctaactc atcaacacga
      181 ggaaggtaaa cgatacggaa gtggtctggt tcctgccagt taaagcctcg accatgaacc
      241 aagagaacct tttcctgctt caagaaatca aggacaaact gctcatcatc atcgatacgg
      301 tacatattgc ggtcgatttt tgggaagata tagagccccg ccttgggttt aacggcagac
      361 aaacctggaa tatcttgaat ggcattatag atgaaatttc tttgctcgta gattcgtcca
      421 ccaggaagaa gcaattcatc gactgattgg tgacccccca aggaagtttg tacgacttgt
      481 tgggccaaaa cgttagagca aaggcgcata ttggacagca tattgagccc ttcgatatag
      541 cccttaacat gagtcttagg gccagacaag accatccaac ccacacggaa acctgctatg
      601 cggtgggatt ttgacagacc attcatgctg acacagaaga catctggtgc caagctcgcc
      661 acaggcgtat gcacatgtcc gtccattacc atgcggtcat agatttcatc cgcaaagata
      721 atcaaatcgt tttgacgggc aatctcaata atctccagca agagttcctt aggataaagg
      781 gctccagttg ggttatttgg attgataagg acaattgcct tggtattgga agtgattttt
      841 gacttgatat cgtcaatatc tgggtaccat tccacagctt catcacagat atagtgaacg
      901 gcatttcctc cagctaggct gacagccgcc gtccatagag gatagtctgg cattggcact
      961 aagacctcat ccccattgtc caaaagcccc tgcatggaca tgacaatcaa ctcactgaca
     1021 ccatttccaa ggtaaatatc atcaatatct acgtttggga atttcttcag ctggcaatac
     1081 tgcatgatgg ccttacgggc tgagaaaatc cctttggagt cagaatagcc ttcactatca
     1141 cgcgcattca taatcaagtc atgaatgacc tcgtctggcg ctgtaaagcc aaattctgct
     1201 ggatttcctg tattcagacg taaaatcttt tctccattcg ctcgcatccg catggcttct
     1261 tccaatacag gaccacggat atcataagca acatgctcta acttactaga cttgttatat
     1321 tctttcatct tgtttcctca attcatcagg atagtaacat tataccacta gaaagagaat
     1381 gcgacaagtt tactgaaatg tgttactagt ttcgtataga agaaaaacct tgctaaaggc
     1441 gaggttaaga acgtagagat agcaggtatt ttgcaaagac acatcacata ccaaaagata
     1501 aacctagaaa aaagcaagcc tagaaaggag tcataaagaa gattaaacat gaggaaaagc
     1561 ccccatatca tcaagtaatc ccaacgccca cttcgttttg caactagaaa taagattaga
     1621 tggtagagta catgaaaaac taaaaatcca ataaaacttg gataaagaag cggtaccaga
     1681 ctctctaatt gacagatcat gatcacttct accaagactg aaactaggat aattccataa
     1741 taaaggaaat ttgatttttg aaaagagttt ttcatcattc tcccttcctt cacttctttc
     1801 ctgctatcct ttcttttatt ttatcatata tttatataga gtttaagccc taatattctt
     1861 ttgaaaaata ctttttttgc tttacttcta tagtgaaaag gtttacaatt atagtaagaa
     1921 aatttcagga ggtttcatta tggcacaacg ttaccaaaat atcatggtcg caatcgatgg
     1981 ttctaaggaa gcggacttgg cttttgtcaa gggagttcat tctgctctac gaaacgacgc
     2041 taaactcacc atcgcacatg tcattgacac acgcgctctc caaagcgtat ccacctttga
     2101 tgctgaagtt tacgaagaac tccaagtcga cgctgaaagt ctgatgaaag agtacgaaaa
     2161 acgtgctaaa gatgctgggg tagcagatgt tcatatcgtc attgaaatgg gaaatccaaa
     2221 gaccctgcta gcacgtacta ttccagatgc cgaggaagtg gacctcatcc tcgttggcgc
     2281 aactggtctc aacgcctttg aacgcctctt ggtcggctct tcatctgaat acatactccg
     2341 ccatgctaag gtcgatttgc tggttgtgag agaacaagaa aaaaccttat aatcacaaag
     2401 aaaaggagcc cctagctcct ttttgtttac gatttatttc tctctttatg gcgttcgtaa
     2461 gccttgagct ggcgctgcag ttccttttta atagcaggtt ctggagcata tttttcttcc
     2521 caattatctg gttttaagat tttatgggtc actggatcaa aatgagcctt gccatctgga
     2581 aaaattttcc ccatattggc ctgatggaca atatcaaaaa tacgttctgg gtccaccccc
     2641 atcaagacaa aactgccgta ggtgaagtaa agcgtgtcaa tcaaggcatc cacttgccct
     2701 atcaaatctt gctgagcagg tgtcttcttg gctactttac ctgctgcctt atcaagggcc
     2761 tgatgaagtt gcgatacagc ttgaccaaaa tcttcttcag aaggactggc tgatcgaaca
     2821 aactccacca attcttctat tttaaaacca gccctatggg ttgcaccctc taaatcccaa
     2881 gctcgaggtt cttcttgggt tcgttcatcc atcatgtggt ggaaggtctt gaccttattg
     2941 aaatgatagt cacggctgac aaaaactttt tctgaagaca aaacaccaaa atgttccaag
     3001 gccttgtgga tcccatcttg ttgattgcta gtggtaatgt gcttggcagc ttccttgaca
     3061 ctgctactac catttcccat agcgaccgac ataccgacgc cagccagcat ttcaaggtca
     3121 ttatctgagt caccaaaagc catgacttgg ttgaggtcaa agccatattc tttcccaact
     3181 cggcgaatgc cttctaattt agaatttccc tgattgatga catccgatgc aaaaggattg
     3241 ctacgtgtca atttcaagtc ttcaaaatca gctgccgcct tctcagattc ttctggtgtc
     3301 atcagcatca aaacttggta aataggttga ttcatcaggt gaagcaggtc ctcttccttt
     3361 tggggaacaa ccttgctgac catgcgatta aaagactgac tcaccgtccg agttaaaaca
     3421 gagggaacga agcgactaat tcgttgggaa aaagaaccca gaccaaagga catgatttta
     3481 gaacccaaca tggcatcctt ggtccctaag gcaatctccg tgccctcttt tttagcatag
     3541 ctaattagat ggcgcaaatg taacttggaa atagggctcg tgaacaagac tctgtcttta
     3601 ctaaagatat actggccatt ataggttacc gcaaaatcca gatccaaatc gtccatcaat
     3661 tccttaacaa aaaaaggtcc tcgccctgtc gctacgccaa ctagtacccc ttgttctttg
     3721 acaatcttaa tcgcatcctt agtagatttc aaaacactct tgcgattgtt gaccaaggtt
     3781 ccatcgatat caaaaaaaac agctttgact tccatcctat cccaatctcc ccttttgtga
     3841 tacaatgatt ataccacatt tcagaaagag tgagtaaatc atgcctaaga aaatccttgt
     3901 tttacatacg ggtggaacta tttccatgca ggccgatgct tctggcgctg ttgtgacgag
     3961 ttcagataat cccatgaacc atgtgtccaa cccacttgaa ggaatccaag tccacgcctt
     4021 ggactttttt aaccttccaa gtccccatat caaacccaaa catatgctgg tcctctacca
     4081 gaaaattaaa gaggaagcag ataactacga tggagtggtg atcacacacg gaaccgatac
     4141 tttagaggaa acagcctatt tccttgatac catggaagtt ccccatatgc ctatcgttct
     4201 aacaggagcc atgcgtagct ccaatgaact cggtagtgat ggtgtttata attacctaag
     4261 tgctttacga gtggccagcg atgacagggc tgctgacaaa ggagttttgg tcgttatgaa
     4321 cgatgaaatc cacgctgcca agtatgtcac caaaacacat acgactaatg tcagcacctt
     4381 ccagactcca acacatggcc cccttggtct catcatgaaa caggaaatcc tctacttcaa
     4441 aacagctgaa cctcgtgttc gctttgacct tgatcacata caaggtttag tccctatcat
     4501 ctcggcttat gctggtatga cagatgagct gattgatatg ctggatttag aacacttgga
     4561 cggtttgatt atccaagcct tcggagctgg taatattccc aaagaaacgg ctcaaaaatt
     4621 agaaagcctt ctgcaaaaag gaattccagt cgctctggta tcacgatgct ttaacggtat
     4681 tgccgagcct gtttatgcct accagggtgg gggcgtacag ttgcaaaaag caggcgtttt
     4741 ctttgttaaa gaactcaacg cccaaaaagc tcgcttgaaa ctcctcatcg ccctcaatgc
     4801 cggactaaca ggacaggctt tgaaagacta tatggaaggc taatactctt cgaaaatctc
     4861 tgcaaaccac gtcacgtcgc cttaccgtat gtatggttac tgacttcgtc agtttcatct
     4921 acaacctcaa aacagtgtgt tgcgcagcct ttaaccagcc gcctagtccg ctctatggta
     4981 ttcattaagt caacatctct tgtttaagag cacaaaatca ggaaatcttc tcgattccct
     5041 gattttttct atttacgttt tcgtgttgag ctacgttctg tcaaaccatg aggtaagaga
     5101 acttcacgtt cttccaactc ttccttatgc ataatcttgg tcaacatacg catactaatg
     5161 gcaccaaggt cataaagagg ttgggcaatc gttgtcaagt ttggacgggt aaagcgtgag
     5221 atttgtgaat catcactagt aataatttca aaatcttctg gcacagaaac acccttatca
     5281 gccaaaccgt tcaagactcc tgctgccaac tcatcacctg tcacaactgc tgcagttgca
     5341 tttgatgaaa tcaaacgctc tgctaaggcg taaccatcat catagctata tttagattca
     5401 aataccaaac cctcactata agtgattcct gcttttttca aggtttcctt gtagccaact
     5461 aaacgaacct taccattgat gtcatccact agcggaccgc taacgaaagc aatacgctca
     5521 ttttctttaa caaggtaact cactgcatca attgttgctt gcttatagtc aatattgaca
     5581 cttggcaact ggtgctcaac atcgacagtt cctgcgagaa caatcggagt acgtgaacgc
     5641 gaaaattctg agcgaatttt atctgtcaag tgataaccca tatagataat gccatctacc
     5701 tgctttgaaa agagggtatt gacaacagaa acttctttct cgttatcttc atcgctatta
     5761 gctaggacaa tattgtactt gtacatttct gcaatatcat caatcccctt agccaaactc
     5821 gaaaaataac cattggtaat atttggaatc acgacaccga cagtggttgt ctttttactt
     5881 gcaagaccac gcgcaactgc atttggacga taatccaaac gatcaattac ctctagcact
     5941 tttttacggg tattctcttt tacattttta ttgccattga ccacacggct gaccgtcgcc
     6001 atggaaacac ctgcttcacg agcgacatca taaatggtta ctgtatcatc tgcattcatt
     6061 ccttttcctg tcctttctat ctcacacatt cttttacaag tagaggtgct gattgaagct
     6121 ctatatctac ttacaaaagt gaagatgtga aaatttcgtt ttcatatttc tacttattcc
     6181 attctatcac taattgtaaa cactttcaag tgttttttga agattgattg aaaaaatttc
     6241 atagaaaacc taggtttagc tccttgctac caccttagac taaacaaaaa ggaggaaact
     6301 aagccctcct aaagttatag taaaatgaaa taagaacagg ataaatcgat caggacagtc
     6361 aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt caatctacta
     6421 taggtattgt tccattcact accgtcaatt ttagcacata gtcttcataa aatattatat
     6481 catcataacc aaccagattc ttttgcgata ttagctgcct ctgttcgatt accagcatcc
     6541 agttttgaaa gaatattggt gacatagttt cgaatagttc cgtttgagag gtaaagctga
     6601 tctgcgattt cttggttgga taagccccgg gcgattccct ttaagacagc aatctcttgt
     6661 tctgtcaacg gattgggacg ggtcatcacc acttccatca attcaggcga atactccttg
     6721 cgtccttcga ggacggtgtg caaggtttgc atgaggtctg caatgcttcg ttcctttaat
     6781 acataagcat ctactccagc cttgaccgca cgttcaaaat accctgggcg cttgaaggtc
     6841 gtcactacaa ccacctttgt ttcgagcttt tctgctcgta tccactccaa gacttcgagt
     6901 cctgtcttaa caggcatttc tacgtcaagg atggcgatat ctacagactc cttttctaat
     6961 agttgaattg cttcttgacc attcttggct tgtaagacag actctacatc tgcttgaaag
     7021 gcaagcaact ggcacatggc atctcgcaac atactttgat cttctgcgac taatactttc
     7081 atctactttc tctccttata aggtagtcga acttgcactt ccgttggatg tttctgactg
     7141 attacactta cttctcctga aaatggagaa acacgatctc ggactgtatg gagctcatct
     7201 ccttttagaa aagcaaagcc gcagccatca tcacttactg ttaaaatgag ttctttctct
     7261 gcccgttcta atttcaggta ggccttcgac gctttggcat gtttgataat attggtcacc
     7321 aactcaagca aaatcatgga agccgttgac tccaattctt gagtaagact agcagtatct
     7381 agttggttat ccgtttccac ctcaattcca gcaatttcta acatcttttt cacagtctct
     7441 agttcggatg tcaaagttct agacttaaga ttttccacaa tggttcgcac ttcattcatg
     7501 gaatccttac tgatctggtg aatttctttt aattcctttt ccacctgtgg ataagcctcc
     7561 atctgaaata actgcaaggc taaatctgtc ttgacactca acatagcaaa ggtatgtccc
     7621 aagctatcat gcaaatcctg accgatacga ctgcgttcat tttcagcaag caatagattt
     7681 atctgggcat tttgcttgac ctgagcttct ttcaaatcct ccacaatacg aatccgaacc
     7741 aagccaaaag tcattaaatc gacaaaagca agaattacaa gtagatagaa tagaaactca
     7801 acttcgattc tctgaaaaat caacagttgg cccacaacaa ggacttgagc aagaagaaaa
     7861 gtccagacat gtaaagactt taaaccacct acgctgaaat gataacttaa gagattggat
     7921 aggaaaaaga aaaaccagat ataattaaca gcaacaaagg cagtattccc aactacataa
     7981 gtcagcatga ggccccaata tagccaagat aggcgctggc tcttagttgt taaaacaccc
     8041 aaatacgcca ctacaaatag aatatcaatc aataaatgcc agctaggaat ctccccagtc
     8101 actacaggta ggatggggaa aatcataaaa attaaactgg cccaatacat atagtctatg
     8161 ctttttagtc tttcaagcat taagcattct ccttatgacc ttgaagataa atggtcaaac
     8221 caaacaaaac tgctgaaaaa acaagtatat aaactgtggc tgatagattg atgccaccct
     8281 cgtttaagaa ggttttgagc aactccatca actgataagt tggtaggcac ttcccgattg
     8341 cttgcatcca gtctggaaat aaagagatgg gcatccagag tccgcctaaa acagccaagc
     8401 ctagatagag aagattgccc acgacagaca tcaactgact agaaggcaag agtgtcaagg
     8461 tcaagccaag cgctacaaag gcaacacttc ctactattag caagaacgca gccccaatcc
     8521 agcttcctag aggcatatcc acacctctta caaaatgccc aactgagaaa acaaccagaa
     8581 ttgataccaa ataatcaacc atcatacttg ttatctttga tagataatat tctaccatat
     8641 ttacaggggt atggcgcaat gttttctgcc agttgttgat tttatcagta tgtaagacag
     8701 ctgggaatga aaacatagct gtcgacatca tggaaaaggc tgtcatggag atgaggtaat
     8761 cacgcataaa attcgcgagt tcacctggtg tgtcctgata gataccagaa aaaaataaat
     8821 agaaagccgt cggcatccct accgacaata gataatagat taattgtcgt ttggtcaata
     8881 aaaattctat cttactaagt gctatccatc gtttcatctt agttatctcc cttttgtgtt
     8941 tcttcaaaga ttgtattcaa caaactacga ttattaactt cgatttcttg catcctacat
     9001 cctgcttggg ctaatagttc ccagaaagca tctgcttctc gagtgactac ttgtagagca
     9061 tcctgttttt gtgaccagtt ttcaaccaag ttagactgct caatgacttc cttgtatgcc
     9121 agaggaagga taaaatgctt ttcaattccc tcactacgca tagctagagg cgtcgtatca
     9181 cgaatcaact ctcccttatt taaaaccaaa atccggtcag ccgtatgctc tacctcttca
     9241 atataatgag acgaatagag aatcgtgact ccttgcgctt ttaggtcccg aacgatttcc
     9301 caaaagcgtt gacgagttga agtatccatg gcagcagttg gttcatctaa aaagacaagc
     9361 tttggtcgcc caatcaaggt caagacaaaa gagaagagac gcttttgccc gcctgacaat
     9421 ttttctgcga attgctcttt ttgttgctgg tcaaactgca atagttgatc gatttcctga
     9481 tcgctcaagg aatttggata gatacgttga aagaaagcaa tcaactcttt gacctttaat
     9541 ttctgaacga tgacattttc ttgaggcaga taacctctaa tatagtctaa ctgagaactc
     9601 gtcactgaca agccttggat ggatacttga ccgcttgtga ccagtttatc tccaagcaga
     9661 cagtccaaga gtgtggtctt cccagcacca ttgggcccaa tcaaggcgac gcattcacct
     9721 tcagctacct caaaggaaat acccttcaaa atagccttgc ccttgatgtt tttatttagg
     9781 ctttctacct taatcatatt catgatattc tcctttcaac cactccattc tcataaggaa
     9841 aacgacgaaa atcataaatc caaaccccaa agcaccacga atgaattggc gaagcaaggt
     9901 ttggtcaaac caacctgtaa acatttccac taaccatacc aagagtgaca ggccgataaa
     9961 gaaatagatg atccctctct tcattcctca aactcctttt tcacatctcc gactaatttc
    10021 aaaccttctc taacaagcca agacatcatt ccaaagccag caaagagctc ccaaggaaaa
    10081 tgatagaaac tctcatccaa tcccgaaaac atgagttagg tcataactcc tgctactact
    10141 aaactcactg cgataatcat tttatttctc atctcttctt cctccatttc atactacaat
    10201 tatagtcttt tgaaatcaga ggagacagaa gcttctgtca ctagaaaata tgacaaatgt
    10261 cataaaaaat tctgttcaaa acaagcaaga tacactatac aataaaacac aatcagaaaa
    10321 atctaaggca acttcctcaa aagagatatc aaacccaatt cacaccataa tgtaaactaa
    10381 tacttattta aaatcaaaaa gagtagaaat ttttatcaga caaaca
//
LOCUS       DAVKBK010000063        10276 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVKBK010000063 DAVKBK010000000
VERSION     DAVKBK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.063"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..389
                     /locus_tag="VWX69_001717"
                     /pseudo
     CDS             1..389
                     /locus_tag="VWX69_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            475..687
                     /locus_tag="VWX69_001718"
                     /pseudo
     CDS             475..687
                     /locus_tag="VWX69_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            587..1033
                     /locus_tag="VWX69_001719"
     CDS             587..1033
                     /locus_tag="VWX69_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9193026.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1171..2475)
                     /gene="eno"
                     /locus_tag="VWX69_001720"
     CDS             complement(1171..2475)
                     /gene="eno"
                     /locus_tag="VWX69_001720"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU9193027.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2639..3085
                     /locus_tag="VWX69_001721"
     CDS             2639..3085
                     /locus_tag="VWX69_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU9193028.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3082..3885)
                     /locus_tag="VWX69_001722"
     CDS             complement(3082..3885)
                     /locus_tag="VWX69_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU9193029.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3894..4223)
                     /locus_tag="VWX69_001723"
     CDS             complement(3894..4223)
                     /locus_tag="VWX69_001723"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU9193030.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4168..4539)
                     /locus_tag="VWX69_001724"
     CDS             complement(4168..4539)
                     /locus_tag="VWX69_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU9193031.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4598..6031)
                     /gene="glgA"
                     /locus_tag="VWX69_001725"
     CDS             complement(4598..6031)
                     /gene="glgA"
                     /locus_tag="VWX69_001725"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU9193032.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6028..7167)
                     /gene="glgD"
                     /locus_tag="VWX69_001726"
     CDS             complement(6028..7167)
                     /gene="glgD"
                     /locus_tag="VWX69_001726"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU9193033.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7157..8299)
                     /locus_tag="VWX69_001727"
     CDS             complement(7157..8299)
                     /locus_tag="VWX69_001727"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU9193034.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8289..10217)
                     /gene="glgB"
                     /locus_tag="VWX69_001728"
     CDS             complement(8289..10217)
                     /gene="glgB"
                     /locus_tag="VWX69_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU9193035.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELREKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3139 a         2270 c         1818 g         3049 t
ORIGIN      
        1 caccaagtaa aaggaacaaa accaagaaaa gttgatagag atagacttaa aaactatctt
       61 actgacaatc cagacgctta tttgactgaa atagcttctg aatttggctg tcatccaact
      121 accatccact atgcgctcaa agctatgggc tacactcgaa aaaaaagaac cacacctact
      181 atgaacaaga cccagaaaaa gtagccttat ttcttaagaa ttttaatagt ttaaagcacc
      241 tagcacaggt ctaacaaatg aatggtgagt taatcgctcc aatgacttac gaagagacga
      301 tgacgagcga cttttttgaa gcttggtttc agaaatttct cttaccaaca ttaaccgcac
      361 cattggttat tatattaaaa cgaagtaaga ataggacaaa tcgatcagga cagtaaaatc
      421 taattctaac aatgttttag aagtagaggt gtactattct agtttcaatc tactatatta
      481 atggacaatg caagattcca tagaatgggg aagctagaac tcttgtgtga agagtttggg
      541 cataaacttt tacctcttcc tccctactcg cctgagtaca atcttattga gaaaacatgg
      601 gctcatatca aaaagcacct caaaagggta ttaccaagtt gcaatacctt ttatgaggct
      661 cttttgtctt gttcttgttt caattgacta tataaattgt ctaagcgaaa caaccgataa
      721 gaattggcac aaaagcgacc gtatttttgt taccaataca ggaaaaccag ttcatagttc
      781 tatcttgagc aagtctctcc agcgagcaaa cgaacgcctt aaaaaaccaa ttcccaaaca
      841 tctgtcccct cacatcttca gacacaccac tattagcatc ttatcagaaa ataaaattcc
      901 tttaaaaaca atcacggaca gggttggtca ttccgactct gaagtcacta cttccatcta
      961 cacccacgtc acaaagaaca tgaaagatga agcaatcaat gtactggata aagttatgaa
     1021 aaagattttt taaaaagttt tgtccctttt ttgtcctcta aatacaaaaa tagcccttcg
     1081 gataaaatcc gaggggctag aaacgttgtt aaatcaacgg ccgaactttt gaatttcatg
     1141 gttcgggata aaatagttca ctgaactatt ttatttttta aggttgtaga atgatttcaa
     1201 tccacgatat tcagctactt caccaagttg gtcttcgata cgaagcaatt ggttgtattt
     1261 agcgatgcgg tctgtacgtg aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac
     1321 tgcaatatca gcgattgttg aatcttcagt ttcacctgaa cggtgtgata caacagcagt
     1381 gtaaccagct tctttagcca tttcgatagc ttcaaaagtt tcagtaagag taccgatttg
     1441 gttaactttg ataaggattg agttagcagc accttcttgg ataccacgtg caaggtagtc
     1501 agtgtttgtt acgaagaagt cgtcaccaac aagttgtact ttcttaccaa gacgttcagt
     1561 aagagctttc caaccatccc agtcgttttc atccatacca tcttcaatag tgatgattgg
     1621 gtatttgtta accaattctt caaggtagtc gatttgttct gcagatgtac gaacagcagc
     1681 accttcacct tcaaatttag tgtagtcgta aactttacgt tctttatcgt agaattctga
     1741 tgaagcacag tcaaatccga taaatacgtc tttacctggt acatatccag cagcttcaat
     1801 cgcagcaagg atagtttcaa caccatcttc agttccttcg aaacgaggag cgaatccacc
     1861 ttcgtcacct acggcagttt ccaaaccacg tgatttaagg attttcttaa gagcgtggaa
     1921 gatttcagca ccgtaacgaa gggcttcttt aaatgttggc gcaccaactg gcaagatcat
     1981 gaactcttgg aaagcgattg gagcgtcaga gtgagaacca ccgttgatga tgttcatcat
     2041 tggagttgga agaactttag tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag
     2101 gtagtcagca gcagcacgag ctacagcgat agacacaccg aggattgcat tcgcacccaa
     2161 tttacctttg ttaggagtac cgtcaagtgc aatcatagca cggtcaatag cttgttgatc
     2221 acgtacatcg tagccaatga tagcttcagc aatgatgttg tttacgttgt caacagcttt
     2281 ttgtgtacca agaccaccgt aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg
     2341 ttcaccagta gaagctcctg atggaaccat accacgtccg aaagcacctg attcagtgta
     2401 aacttctact tcaagtgttg ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc
     2461 agtaataatt gacatttttt actctcctta tgagttaaat tttttacacc tctataatac
     2521 cttaaaaccc ctcctttttc aagaaaaaac gttatctttg tgcaactttt ccttaacttt
     2581 ataaagtaat cgctttcttt tgtctgtttt attctaactt ttatgatata ctgttttcat
     2641 gacagattta tcaaaacaat tacttgaaaa agctcatggt gggttaaaaa taaatccgga
     2701 tgagcaaaga cgctatcttg gtacttttga ggaaagagtt cttggatatg tagatattga
     2761 cacagcaaat agccctcagt tagaaaaagg ctttttattt attttagaaa accttcagga
     2821 aaaagcaaag ccactatttg tgaagatttc accaactatc gaatttgata agcaagtttt
     2881 ctacttaaaa gaagcaaaag aaactgatag tcaagccacc atagtatctg aagagcatat
     2941 tacttctcct tttggcctgg ttattcatag caatgcacca gttcaagtag aagaaaaaga
     3001 ccttcgactt gcttttccaa aactttggga agttaaaaag gaagaaccag ccaaaacatc
     3061 cttatggaag aaatggttta gctaaatctt gcacatattt aataagtgcc caatattggc
     3121 agccgtgcgc tccagataga gactggcatt tttcaaacta tcttctaaag gttcactttt
     3181 ctccaaaata gaaaagacag cttggatatt ttcaaatggt aggggaggta aatcttcagc
     3241 aagactaccg caaatagcaa taacaggaac tccaacaggg gttctttttg caacacctat
     3301 aggcgctttc ccagcaaagc tttgactatc aagtcttcct tctccaacaa caaccaagtc
     3361 agcatctgaa actttcttat caaagttgat taagtccaag caggtatcaa ttccagacac
     3421 gatacttgcc tgagcaaagg cacacaaacc agcagcaatc cccagtcctc catcattact
     3481 ggccgtgcca ccaacaccga tataaatatc tttaatccct ttagaaatga gatggagaat
     3541 caactctcca ataccacaag tttggatttg aagtggattt cgtttctcta gcggaatttt
     3601 tccaagacca accaagtcag ctacttcaaa tagtgccagt tccccttttt gaaaatagcg
     3661 catggcttct ttttgtccaa aagggtctgt cacttggatc catttttctt ttaggtcaag
     3721 agaatgtcgg atagcatcta cagtaccttc tcccccatca ccaacagggc agaggagaca
     3781 ttctacatct gctatcgatt gttggaagcc tctttttatt gcttcagcta cctgttgagc
     3841 tgtcaagctt tccttaaacg aatccggtgc aattacaatc ttcatatttt ccctcattct
     3901 aaacagtcaa tcaaaggaag aacttctaaa aaatccctct tgtcaacatg atgtggtatt
     3961 tcttttttga gcatttcttt ggaacaaaag gcgattccta actccgccga cttcaacatt
     4021 aatagattat taaccccatc accgattgcc accgttcttt ctttagaaag ttttagtttc
     4081 tttctccatt tttccagagt ttcttttttg acctggggac ttataatttg tccaactaat
     4141 tttcctgtta aaagaccttc tttgacttca agctggttgg cagtgaaata ggcaatacca
     4201 agggattttg ctaatctctc caactattgg tgtaaatcca ccagacacca gaccaactag
     4261 gatgccattc ttttggagaa tagagatgaa ctctgggaca tttagcgata gatgaattga
     4321 gttgaagacg ttatcaaaga ccaaaatagg aagaccttcc aacaaggaca ctctttttct
     4381 taaactgctt tcaaagacca actctcctcg cattgctcga cttgtaatct gcgaaatttc
     4441 cgcctcatga cctgcctctc tccctaaaag atcaatcact tcttctagga ttaaggttcc
     4501 atctacatcc aaaacacaca agccttttac ttgagacatc agttctcctc tctaaacagc
     4561 ctaaaaatcg tatgaagtca tcatacgatt ttatctatta attaactaaa ctatggtaca
     4621 agtcaaggta tgacttgcag gctgtatccc atgagaagtc actctccata gcttgttttt
     4681 gtaggtttct ccaaatgtct ggatggtttc tatacaagtc caatgctgtt tggaaagtcc
     4741 aatttaacca ataaggagat agattgtcaa agctaaagcc agtaccgctt ccttcgattg
     4801 gattgaaagc gcgaactgta tctcgcaagc ctccaacttc atggaccaat ggcaaggttc
     4861 cataacgcat agccatcatt tgagacaagc cacacggttc aaaacgactt ggcatgagga
     4921 agaggtcaca agcagcgtag atttcctgag caagtttgac atcaaaagtg atatttgctg
     4981 atagcttgtc tgggtaaatc tgagcaaacc atgagaaagc tccttcaaag gctggatcgc
     5041 cagttcccaa aagaacaatc tgaacatctt cttgcaagat atggtgaaga ctttcgacca
     5101 ccacatcaaa acctttttga cgtgtcaaac gagaaacaat tcccaccagt ggaacgtctg
     5161 ctctaacagg caagccaact ctttcttgca attttgcctt atttttggct ttcccagaca
     5221 aatcttcctg attgaaatga tagtctaaaa gagcatccgt ctgaggatta taaagatcag
     5281 catcaatccc attcacgata ccagatactt taccagactc cattttaaga atctgatcca
     5341 aattacatcc aaactgacta gtcataattt catgagcata gctaggtgaa acggttgaaa
     5401 cacggttcgc atagagaata cctgccttca tccagttcag acagttgttc catcgaaggg
     5461 tgccatcagc gtaacgttca aggccaactc caaacaaatc acccaacatt ccttctgaaa
     5521 attgtccttg gaattctaaa ttatgaatgg ttaaaactgt ttcaatgtcc tcataggctt
     5581 gaatccaaca gtatttttcc ttcaacaaga aaggaatcat agctgtatgg tagtcatgaa
     5641 catggagaag atcaggaata aagtcaatcc tttccatagc ctcaatggca gccagttgga
     5701 aaaaggcaaa gcgttctccg tcatcaaaat caccgtaaac atgaccacgg aagaaataat
     5761 attgattgtc aataaagtag aaggttacac catttaatac tgttttctta attccacaat
     5821 actgtctacg ccaaccaacg ctcacctcaa aatgaagcac atcttcaatc tgatttccaa
     5881 atttagcctc taccatatca tagtagggta aaatcactgc aacttcgtgc ccagctttta
     5941 ccagtgattt tggaagagcg ccaatgacgt ctcccaaacc acctgttttt gaaaagggtg
     6001 caccctctgc tgctacaaat aaaattttca tgaatgaata tcctctgtta ctttagcacc
     6061 tttcttaacc acaactggat gttctgcagt tcctcgaatc acaacaccaa gctcaacttc
     6121 aacccctttg tccaagatag catattcgac ctgagcccct tctccaataa caacacgagg
     6181 gaagagcagg ctatctttaa ccaagctatc cttatggaca tgaatattac gtgatagaac
     6241 agaattagct acttgacctt caataatact accagaggca aactgagaag tgcttacctt
     6301 agatgtatta gcatagtaag ttggctcttc gtttttgacc tttgtataaa tcttttggtt
     6361 tggtgagaaa agagaataga atttttgtga ttcaagcata tcgatattcg cttgataata
     6421 agatttaaca gagtgaatat tggctagata gcccgtgtac tcgtaggcaa aagctccctc
     6481 ttttacagcc aaatcccgta aaacatagcg caatttctct ggatgttctt ttttagcttc
     6541 ttcttccaag tgttcaatca accaaggtgt atcaacgaca aagatatctg tagacatatt
     6601 gaacgtttca gctgttgact tgctatcaaa gagtttatga gaaagaacat ggtctgtttc
     6661 atctacatcc aagattgcat ttacttctga aatatctttc ttagctagtt ttttataaac
     6721 tacagtgata ggctcttttg ttgtactatg taggtggaaa acttggttca aatcaatgtt
     6781 aataagaaca tcgcagttga gggcaaccgt ttggtttgag ccagaacgtt tcaaataagt
     6841 aagaagctgt tggtagtatt cttttccaac tgtactactt tctacacggg tattgtaaat
     6901 tcctagatag taatggctaa gaagggttga taagccccac tcgcgccctg aacgaatatg
     6961 gtcaaagact gagctgatat tatcctgctg gaaaatacca aagacactac gaacacctgc
     7021 attagcaagg cttgaaagtg ggaagtcaat caaacgatat ttcccaccaa atggcaaact
     7081 tgctactgga cggtggtccg tcaatgtcga catatcgtga aaaccaactg tatttcctaa
     7141 aatggcagaa tatttatcaa tcttcatctg ttgctacccc cactacttca ttatatccta
     7201 caacttgtac ttcatctgtt ccatcaattt cgacaccgtc agaaataatc gcaccttcac
     7261 caataatggc acgtttaatc ttagctcctt gaccaatgat agctccactc atgataactg
     7321 aatcaaggac ttccgctcct tcgcgaactt gcgcgcctgt tgaaaggata gaatgtttaa
     7381 cagttccatc aacgaaacat ccgtctacaa ctaatgagtc ttccacatga gcatttgccc
     7441 cgaggaagtt tggtggtgaa atcaagtttc ttgagtaaat cttccattga cggttacgac
     7501 tatccaaggc attttctgga gaaatatact ccatgttcgc ttcccaaagt gactcaatag
     7561 taccaacatc tttccaataa ccactaaatt cataagcata aacactttca cctgactcaa
     7621 ggtaatttgg aatgacattt ttaccaaagt ctgacatgcc aaccttgctc ttttcagcag
     7681 cgactaacat attacgaagg cgttgccaat caaaaatgta gattcccata gaagcttttg
     7741 tagatttagg ttgagctggt ttttcttcaa attcaacaat acgattgtta gcatctgtgt
     7801 tcatgatacc aaaacggctt gcttctttaa gagggacgtc taaaactgct actgtcaagc
     7861 tggcattatt atccttatga gactggagca tatcatcata gtccattttg tagatgtgat
     7921 ccccagacaa aatcaagaca tactcaggat tgacactgtc gatatagtcg atattttggt
     7981 aaatagcgtg actagtcccc tcaaaccaac gatttccttc acttgcagaa taaggttgaa
     8041 gaatagagac acctgaatta ataccgtcta gtccccagct tgaaccattc ccaatatggt
     8101 tgttgagagc aagtggttga tactgtgtaa cgaccccaac attatgaatc cctgagttgg
     8161 cacagtttga tagggcaaag tcaatgatac ggtagcgccc accaaattgc acagctggtt
     8221 ttgcgatgct ttgagtgagt ttaccgagac gagttccttg cccaccagca agaatcaaag
     8281 ctaacatttc atttttcatt ttctactcct ttttggtttt tatttgtgac ggttttagta
     8341 gatttcaagc gacgtttgat tttccataca cttgctccca tagccggtag ggtaaaggtt
     8401 aaggtctgct cataatcttt ccatagtcct tcttgcgttt gaacagtttg attatgttct
     8461 ttccaaacgc ctccccactc ttccaactca gtattccata cttcttcgta aattcctgca
     8521 acgggtagtc cgattgtaaa atctttccgc tcaacaggta ccatgttaaa gatacagact
     8581 aacatttctc cctttttacc cttacgaata aaggaaagaa cactctggtc tcgattatcc
     8641 gcatcaatga tttcaatacc atcatagctg gtatcgattt cccacagaca gcgatgatct
     8701 ttgtaaaact ggtttagctg agaagtgaaa tacttcatct tagcattcat tgggtcttct
     8761 aggttagacc attccaactg ttcttcagat ttccattcta ggaattgacc gtattcgcta
     8821 cccatgaaga gcaatttctt accaggatga caaatttggt acgtatagag attgcgcaag
     8881 cctgcgaatt gattgtaacg atctccccac atcttatgca tcatactctt cttgccatga
     8941 accacttcat cgtgcgagaa tggcaagaga taattctcct tgaaaacata cataaagctg
     9001 aaagtcacca ggttaaagtc atatttacga tagatcggat cttcttcgta gaaacggagg
     9061 atatcattca tccagcccat gttccatttg tagtcaaatc ctagaccacc aatctctttc
     9121 attcccgtaa tcttggtcgc agacgaactt tcttctgcaa tcatcatcac atctggatat
     9181 tctaacttaa taacctcatt caagcgctga aggaaataat aaccttcata gttgagattt
     9241 ccgccatctt tattaggtgt ccatggagca tcatcatagt ccaaatagag catgttgcta
     9301 acagcatcca cacgaatacc atccaaatga tagacatcaa tccaatgctt aatgcaagaa
     9361 attaagaagg actggacttc attttttcca aggtcaaaat taagggcacc ccaaccatgg
     9421 ttatgagcct tattatggtc ttggtattca aaagtcggtg tcccatcata ataggctaag
     9481 gcatcatcgt tgatggtaaa gtgacctggt acccagtcca caataacccc aatattatgg
     9541 gtatgacact cctcgacaaa atcttgaaac tcctctggtc ggccataagc atgctctaaa
     9601 gcgaagtaac ccataagctg atacccccaa ctcaagccca aaggatggga catcaagggc
     9661 ataaactcaa tatgagtata gttcatttca acgagataag gaatgagttc atccttgagc
     9721 tgggcaaaac tataaggact gccatcagaa tttcttttcc atgatccagc gtgaacttca
     9781 taaatattga caggacgctc ttcaaagccc caacgttttc ttcgtgccag ccaaagtcca
     9841 tccttccatt tcttctcacg aagctctgtt aagattgccc ctgttcctgg acgagcctca
     9901 tacctgacag caaaagggtc aatcttcatc agttgatgac cattttgacg tgtgacatga
     9961 tatttgtaaa tatgcccttc ttgagccata ttggtaaaga cttcccagac cccaaaatca
    10021 tttcttacca ttggaatctg attttcaatc cagttggtaa aatcaccaac caagtgaaca
    10081 gcctgagcat taggtgccca aacacggaag gtatagccat gctctccatt tagttcttcc
    10141 ctatgtgctc ctagataatg ttggagataa aaattttcac ccgtcataaa ggtttttaat
    10201 gcttctctat tatccatata ctccccttct cctgtaagcg ttttctatgt ttttattata
    10261 ctaccttttt agagaa
//
LOCUS       DAVKBK010000064         9437 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVKBK010000064 DAVKBK010000000
VERSION     DAVKBK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.064"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            476..1762
                     /locus_tag="VWX69_001729"
     CDS             476..1762
                     /locus_tag="VWX69_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9193036.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            1777..2088
                     /locus_tag="VWX69_001730"
     CDS             1777..2088
                     /locus_tag="VWX69_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193037.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            2348..3076
                     /locus_tag="VWX69_001731"
                     /pseudo
     CDS             2348..3076
                     /locus_tag="VWX69_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            3539..4304
                     /locus_tag="VWX69_001732"
                     /pseudo
     CDS             3539..4304
                     /locus_tag="VWX69_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            4320..4799
                     /locus_tag="VWX69_001733"
     CDS             4320..4799
                     /locus_tag="VWX69_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193038.1"
                     /translation="MKLNKQKNRMIYVLSNFLYAISVSIIYALNGIVLLVIVSKLGIP
                     GDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYKLKSGLVFGILVALLLFIPNILNTMM
                     MNTSNDLFIKAIELLPFYSLPVFVASNTMSISQYLVVITTIILLYFFTLKKSKKYSF"
     gene            5185..5394
                     /locus_tag="VWX69_001734"
     CDS             5185..5394
                     /locus_tag="VWX69_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9193039.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            5384..5872
                     /locus_tag="VWX69_001735"
     CDS             5384..5872
                     /locus_tag="VWX69_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193040.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            5988..7448
                     /locus_tag="VWX69_001736"
     CDS             5988..7448
                     /locus_tag="VWX69_001736"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU9193041.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAVRIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            7445..8269
                     /gene="nadE"
                     /locus_tag="VWX69_001737"
     CDS             7445..8269
                     /gene="nadE"
                     /locus_tag="VWX69_001737"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU9193042.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            8619..9170
                     /locus_tag="VWX69_001738"
     CDS             8619..9170
                     /locus_tag="VWX69_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9193043.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
BASE COUNT         2948 a         1594 c         2001 g         2894 t
ORIGIN      
        1 ttctttgagc ttttttcttt ttaaatattg attgtttcta aaagttctag taatattgct
       61 atttctcatt tttccaaata tgttattcaa cttattagct acgtctctat tcatatttgg
      121 gtataaaaca aaaaatcaat tctaacagtt ttatatcaga ataataaata aaaaagcgat
      181 attctagact gtatcaatcc ttttccatta taggagcaac agagtgggag tagtcatcta
      241 aggactaatt tatgtatttt tacgagtcag tatcttggga tactggtttt tactttttta
      301 gactttttga ctacttgtta aaactggggt aattttcgac tgtttaacag ttattatgca
      361 aagtctaaaa gattagaatt gtcaaaacaa tccgtctagg cttgatttta tcctttattt
      421 actataaaat gagaaggaaa aatgtcaaac ttttatattg caaataggag aaatcatgac
      481 aaaaacatta aaacgtcctg aggttttatc acctgcaggg actttagaga agctaaaggt
      541 agctgttcag tatggagcag atgctgtctt tatcggtggt caggcctatg gtcttcgtag
      601 ccgtgcggga aactttactt tcgaacagat ggaagaaggc gtgcagtttg cggccaagta
      661 tggtgccaag gtctatgtag cggctaatat ggttatgcac gaaggaaatg aagctggtgc
      721 tggtgagtgg ttccgtaaac tgcgtgatat cgggattgca gcagttatcg tatctgaccc
      781 agccttgatt atgattgcag cgactgaagc accaggcctt gaaatccacc tttctaccca
      841 agccagtgcc actaactatg aaacccttga gttctggaaa gagctaggct tgactcgtgt
      901 cgttttagcg cgtgaggttt caatggaaga attagctgag atccgcaaac gtacagatgt
      961 tgaaattgaa gcctttgtcc atggagctat gtgtatttca tactctggac gttgtactct
     1021 ttcaaaccac atgagtatgc gtgatgccaa ccgtggtgga tgttctcagt catgccgttg
     1081 gaaatacgac ctttacgata tgccatttgg gaaagaacgt aagagtttgc agggtgagat
     1141 tccagaagaa ttttcaatgt cagccgttga catgtctatg attgaccaca ttccagatat
     1201 gattgaaaat ggtgtggaca gtctaaaaat cgaaggacgt atgaagtcta ttcactacgt
     1261 atcaacagta accaactgct acaaggcggc tgtggatgcc tatcttgaaa gtcctgaaaa
     1321 gtttgaagct atcaaacaag acttggtgga cgagatgtgg aaggttgccc aacgtgaatt
     1381 ggcaacaggt ttctactacg gtataccatc tgaaaatgag cagttgtttg gtgctcgccg
     1441 taaaattcct gagtacaagt ttgtcgctga agtggtttct tatgatgatg cggtacaaac
     1501 agcaaccatt cgtcaacgaa acgtcattaa cgaaggggac caagttgagt tttatggtcc
     1561 aggtttccgt cattttgaaa cctatattga agatttgcat gatgccaaag gaaataaaat
     1621 cgaccgcgct ccaaatccaa tggaactatt gactattaaa gtcccacaac ccgttcaatc
     1681 aggagacatg gttcgtgcat taaaagaagg actcatcaat ttttataagg aagatggaac
     1741 cagcgtcaca gttcgagctt aagaaaggaa aaggaaatga tagaggcaca gggtttctta
     1801 gtggataagc aaacaagatg cattcattac catagcaagc tggatattat tgctttacaa
     1861 tgctatgatt gtaaaaagta ttatgcttgt tatcggtgtc atgattcatt agaaaatcac
     1921 ccttttgagc cttatccctt atctttgata caggataagc ctattttatg tggtgtttgt
     1981 ctaaaactat taacatataa gcaatataaa gaaagcttaa gttgcctctt ttgtttttct
     2041 cgctttaatc caggttgcca aaatcataag gaacgctatt ttaaatagca aatcatctag
     2101 ttttgaagta ggagaaaact caattccaag agaaaatgaa gtaaatcttc ccacaataaa
     2161 acgcataata tcaagattgt tcaatacctg atactatgcg tttttaagat tttaaagact
     2221 tttttcctag ccccttttta ctttatctgg tattttgact acttgttaaa actggggtaa
     2281 ttttcgactg tttaacagtt attatgcaaa gtctaaaagg ttagaattgt caaaacaatc
     2341 cgtctagagt atgcgtgatg ccaaccgtgg tggatgttct cagtcatgcc gttggaagta
     2401 cgacctttac gatatgccat ttgggaaaga acgtaagagt ttgcagggtg agattccaga
     2461 agaattttca atgtcagccg ttgatatgtc tatgattgac catatctcag atatgattga
     2521 aaatggtgtg gacagtctaa aaatcgaagg acgtatggag tctattcact atgtatcaac
     2581 agtaaccaac tgctacaagg cggctgtgga tgcctatctt gaaagtcctg aaaagtttga
     2641 agctatcaaa caagacttgg tggacgagat gtggaaggtt gcccaacgtg aactggctac
     2701 aggattttac tatggtacac catctgaaaa tgagcagttg tttggtgctc gtcgtaaaat
     2761 ccctgagtac aagtttgtcg ctgaagtggt ttcttatgat gatgcgacac aaacagcaac
     2821 cattcgtcaa cggaacgtca ttaacgaagg ggaccaagtt gagttttatg gtccaggttt
     2881 ccgtcatttt gaaacctata ttgaagattt gcatgatgcc aaaggcaata aaatcgaccg
     2941 cgctccaaat ccaatggaac tattgactat taaagtccca caacttgttc aagctggaga
     3001 catggttcga gctcttaaag aggggcttat caatctttat aaggaagatg gaaccagcgt
     3061 cacagttcgt gcttaatgta gttgtttagt tttaaaaaat tatgcaaagc tccatataca
     3121 acacttaaac gagattaaag aatggcgaaa tcccttgatg cgcaagagat tagctgtcct
     3181 tttttatttt ttaagtgata aagtcggagc ttaggtatta aagcctatca aattaaacaa
     3241 agaagcgatg tcttagatat tttgaaaaaa attaataagc agaaaactct ctattatttt
     3301 gttgtagaga gttttttgtt aataaaattt tacaaaatga catttatata ttgcattaag
     3361 ttagatatat gatataatat tgttaaaaag aggcgcaact ttttaaactc aataagaatc
     3421 aaagagcaaa ccatgaatat taatggagga ataaaaaatg taagttataa atgtaagtaa
     3481 gcattatggt cattcaatca ttctcaaaga tataaatttt gcacttaaca agggtgaaat
     3541 tgttggtcta gtagggagaa atggagttgg taagagtacg ttgatgaaaa ttcttgttca
     3601 aaataatcaa ccgacttcag gtaatattat aaacagtgat aatgttgggt atttaatcga
     3661 agaaccaaaa ttatttttat ctaaaacagg tttagagaat ttaaaatatt tgtcaaattt
     3721 atatggtgtt gactacaatc aagaaagatt tagaagtttg atccaagagt tagatttgac
     3781 tcagtctatt aataaaaaag taaagaccta ttctttgggt acaaaacaaa aattagcttt
     3841 gcttctaact ctcgttacgg aacctgatat attgatttta gatgaaccga ctaatggttt
     3901 agatattgaa tcatcacaaa tagttttagc ggttctaaaa aaaattagct ttaaatgaaa
     3961 acgtgggaat tttaatatcg agtcataaat tagaagacat tgaagaaatt tgtgagaggg
     4021 ttcttttctt ggagagcggg cttttgacat ttcaaaaagt aggaaaagat agtcataatt
     4081 tcttgtttga gatagctttt tcatcagcta cagatagaga cattttcatt accaaacaag
     4141 aatttgggga tattgttcag gaagagggat tgagaattac tatgtctggg aatattcaaa
     4201 atagtgagct ttttaaattt tttaacgaaa actctattaa agtagttgat tttgaaacta
     4261 aaaaagagac gcttaaagat atttacctaa atcgttcaaa ataaaggaag gttataatca
     4321 tgaaattaaa taaacagaag aatcggatga tttacgtctt gtctaatttt ctatatgcca
     4381 tctcagtttc cattatttat gctttgaatg gcattgtgtt actagtcata gtaagtaaat
     4441 tgggtattcc aggtgattta ggattagatt ttatagtagc tattgtagtc aatacaattt
     4501 tgttagtcct gttttatttt ctattatctt acatttttta tttatacaaa ttgaaaagtg
     4561 gcttggtatt tggtatttta gtagctttac tactctttat ccctaatata ttaaatacga
     4621 tgatgatgaa tactagtaat gatttgttta tcaaagcaat tgaacttctt cctttttatt
     4681 ctttacctgt atttgtggct tcaaatacga tgtctattag tcagtatctt gtggtaatca
     4741 ctacaatcat tttattgtac tttttcactc tcaagaaaag caagaagtat tcattttagt
     4801 ttcatttagt attattttgc atacctaaaa tacaataaaa aaatcagtca tcttggtatg
     4861 ctcctgcttt cactattcaa cacgtttttg acttatacta ggctcatttc caaaagcatt
     4921 atataatagt gatatgaaac caactaaact aaacaagaaa tataagcaat aaaaactcgt
     4981 ttaaaagatc ctactaaagc taatactaaa taaaaataaa agagtaaact aggaagttta
     5041 tttcaaacaa cctaaaatac tgattttcgg ctgaagataa tactggagtg caaattaatg
     5101 gggttataat aaatagctga tagcttgtgt tggttttgga ttttttaaga gtagatgagt
     5161 attaaaacta taaggaggac gaaggtggct aaaaatttaa aattaaaatt agctcgggta
     5221 gagcgtgatt taacacaagg tcaactggca gaggctgtcg gggtgacgcg ccagactatt
     5281 ggtttgatag aagcggggaa atacaatccc agtctctcgc tctgccagtc catttgcaga
     5341 tgtttaggga aaaccctaga ccaactattt tgggaggaag aagatgaaaa atagatttta
     5401 ttattatcaa ttactagacg aaagagaaga acaactgttc aataaagcgg gctctgaaag
     5461 tttctatatc tgcatcgctt tgtcgctcct atcttatatc atttcagtat tagcaccaag
     5521 cctttttaat tctaatatgc tgctaatcgt tatcatcata gggacatttt actttttcaa
     5581 tcgtgcccgt tatctgggag tgacctacta tagtcgtttt cattttacga ttttgggttg
     5641 ttttttccta accttggcta ttacggctct tttgatgttg cagaattatc aattcaacat
     5701 agaaatttat cagcacaatc ctttgaattt taaatacctg tctgcttggg tcattactta
     5761 tatcatttac cttccgtgga tctttattgg caatcttggt cttaagagct atggcgaatg
     5821 ggctcagaaa aaatttgaac aagatatgga tgaattggag agtggagaat agcttgttac
     5881 tcttttctca atccagctaa aatgtgatat aatagtacta atttattgga atacatgaaa
     5941 gttcttgaaa attttcatgg gtttctagct aaggaagtag gaaaagtatg tatccagatg
     6001 atagtttgac attgcacacg gacttgtacc agatcaacat gatgcaggtt tactttgacc
     6061 aagggattca caataagaag gcggtctttg aggtgtattt ccgccaacag ccttttaaga
     6121 acggctatgc ggtttttgca ggtttggaaa gaattgtgaa ctatcttgaa gacttgcgtt
     6181 tttcagatag tgatatagcc tatttggagt cgcttggtta tcatggggcg ttcttggatt
     6241 accttcgcaa tttcaagttg gagttgaccg ttcgttctgc ccaagaaggg gatttggttt
     6301 ttgctaatga accgattgtg caggtggaag gacctctagc ccaatgtcag ttggtcgaaa
     6361 cggctctttt gaacatcgtc aactaccaga ccttggtggc gacgaaggca gttcgtattc
     6421 gttcggttat cgaagatgaa cccttgatgg agtttgggac acgtcgggct caagaaatgg
     6481 atgcggccat ctggggaaca cgcgcagctg tgattggtgg cgccaatgga actagcaacg
     6541 tgcgtgcggg taagctcttt gacattcctg ttttgggaac ccatgcccat gccttggtac
     6601 aggtttatgg caatgactat gaagctttca aggcttacgc tgcgacccac aaaaattgtg
     6661 tctttcttgt ggatacctat gacacccttc gcatcggtgt accagctgcc attcaggtgg
     6721 cgcgtgagct gggtgatcag attaacttta tgggtgtgcg gattgactct ggggatattg
     6781 cctacatttc taagaaagtc cgtcagcaac tggacgaggc tggatttaca gaggctaaga
     6841 tttatgcttc taatgatttg gacgaaaata ctatcctcaa tctcaagatg caaaaggcca
     6901 agattgatgt ctggggcgtg ggtaccaagc tgattacagc ctatgaccag ccagctcttg
     6961 gtgcagttta caagattgtt gcaatcgaag atgaaactgg tcagatgcgc aatacgatta
     7021 agctgtctaa taatgctgaa aaagtttcta cgccaggtaa gaagcaggtg tggcgcatta
     7081 ccagtcgtga aaaaggcaag tcagaaggcg actatatcac ttatgatggt gtggatatta
     7141 gcgacatgac agaaatcaag atgttccatc cgacctatac atacatcaag aagacggttc
     7201 gtaattttga tgccgttcct ctcttggtgg atatcttcaa agaaggaata ttagtttaca
     7261 acttgcctag tttgactgac attcaggatt atgcccgtaa agaatttgac aagttgtggg
     7321 atgagtataa gcgtgtgctc aatccgcagc actatccagt ggatttggcg cgtgatgtat
     7381 ggcaagataa gatggacttg attgataaga tgcgcaagga agcccttggt gaaggagaag
     7441 aagaatgagt ttgcaagaaa cgattatcca agagctgggt gtcaaaccag tgattgatgc
     7501 ccaggaagaa atccgtcgtt ctattgattt cttaaaaaga tatctgaaaa aacatccctt
     7561 cctaaaaacc tttgtactag ggatttctgg gggacaagac tcaaccttgg cagggcgttt
     7621 ggcgcaatta gctatggaag aactgcgagc tgaaacggga gacgatagct acaaatttat
     7681 cgctgtccgc ctgccatacg gagtgcaagc tgatgaagca gatgctcaaa aagctctagc
     7741 cttcatccag ccagatgtca gcttggttgt gaatatcaag gaatcagctg atgccatgac
     7801 agctgcagtt gaagcgacag gtagtcctgt ttcagacttc aacaagggga atatcaaggc
     7861 acgttgccgt atgattgctc agtatgccct tgctggttcc catagcggag cggtcattgg
     7921 aacagaccac gccgcggaaa atatcacagg tttctttacc aagtttggtg acggcggtgc
     7981 ggatattctc cctctttacc gcctcaataa acgccaagga aaacagctct tgcagaaact
     8041 tggcgcagag ccagcccttt atgaaaaaat cccaacggca gacctagaag aagataaacc
     8101 aggcctagct gacgaagtcg cacttggagt cacctacgca gagattgacg actacctaga
     8161 aggcaaaaca atcagcccag aagctcaagc gaccattgaa aactggtggc acaaaggcca
     8221 acacaaacgc cacttaccca tcactgtatt tgatgacttt tgggagtaaa aaggtccggg
     8281 ggaccttttt agcttcttgc cctgaaatta aaaagcaaga aaaacctcca ctggaggttt
     8341 tcagcctctc atcttaaaat aagaaagtga gagaaggtct gggggatctt gaaccccgag
     8401 tttagaaata agaaaatgag gcagattcgg taactcgaag agttcgattt catcgtctta
     8461 cccctgcaac gatgactagg tttgaaaaag cttgctagat cgcatttcaa accaggcagc
     8521 gattgcgtca agaaattaga agacaaactc gttttctagc tgttactgag ttgagccttt
     8581 ttactacgag catagaaata aggaagtgag gtagcatcat gaaatctatt ggtacgcaaa
     8641 tattacagac agaacgtttg attttaagaa gatttgtgga gagtgatgca gaagctatgt
     8701 ttcaaaattg ggcttcatcc gctgagaatc tgacctatgt tacctgggat ccccatcctg
     8761 atatcgaaat cactcgaaac tcgattcgca attgggttgc ttcctatact aatctcaact
     8821 attataaatg ggccatttgt ctaaaagaaa acccagagca agtgatagga gatatcagca
     8881 ttgttaagat agacgaggct gatttaagct gtgaaatcgg ctatgtgcta ggcaaggctt
     8941 actggggaca tggtatgatg acagaggcct tgaaagctat cttggacttt tgttttactc
     9001 aagcaggttt tcaaaaggtc agagcacgtt atgccagtct caacccagct tcaggtcgtg
     9061 tcatggaaaa ggctggaatg tcctatctac aaaccattgt taatggtgta gagagaaaag
     9121 gctatcttgc ggatcttatt tattatggta taagtaggga agaatgttga attctatttt
     9181 ctgtttctat cgaagtcaac tatttattgt aaatataata attagcattc caagtttatt
     9241 tgaaacttta aaatagcata ttgattagta caagacagat gttctagttc cttctttaat
     9301 ctggtttagt attagttaaa aaatcgcttt aagcttgtaa ctaagaggga cctaatcgac
     9361 tagattctcc agccgaacag gtggtaatgt actttttata gtgtaatcct agctgttgtt
     9421 aaatttaaaa tagaatc
//
LOCUS       DAVKBK010000065         9243 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVKBK010000065 DAVKBK010000000
VERSION     DAVKBK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.065"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            444..1919
                     /locus_tag="VWX69_001739"
     CDS             444..1919
                     /locus_tag="VWX69_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU9193044.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(1885..2600)
                     /locus_tag="VWX69_001740"
                     /pseudo
     CDS             complement(1885..2600)
                     /locus_tag="VWX69_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            2856..3716
                     /gene="speE"
                     /locus_tag="VWX69_001741"
     CDS             2856..3716
                     /gene="speE"
                     /locus_tag="VWX69_001741"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU9193045.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            3713..4972
                     /locus_tag="VWX69_001742"
     CDS             3713..4972
                     /locus_tag="VWX69_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU9193046.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            4972..6099
                     /gene="nspC"
                     /locus_tag="VWX69_001743"
     CDS             4972..6099
                     /gene="nspC"
                     /locus_tag="VWX69_001743"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU9193047.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6096..7181
                     /gene="aguA"
                     /locus_tag="VWX69_001744"
     CDS             6096..7181
                     /gene="aguA"
                     /locus_tag="VWX69_001744"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU9193048.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7191..8066
                     /gene="aguB"
                     /locus_tag="VWX69_001745"
     CDS             7191..8066
                     /gene="aguB"
                     /locus_tag="VWX69_001745"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU9193049.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGGVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8247..9056)
                     /locus_tag="VWX69_001746"
     CDS             complement(8247..9056)
                     /locus_tag="VWX69_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9193050.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
BASE COUNT         2708 a         1775 c         2075 g         2685 t
ORIGIN      
        1 tttttatcaa aaaatacttt acaagttctt aaaaacatga tatagtaata aagcttagaa
       61 aatgagatga tgttttctag caaatataaa cccgagtaaa aaatgcctac ggacaggcag
      121 ggttgaatgc cgaagcgtgg ttgaaaagcc acattattga tagggttaaa agcctacttt
      181 tataagttga tgttaggaca cttgtcctaa ttcataaatt tttagtgtgg tgaaagcaca
      241 cgtcatcttg tgaaacgatc aataaagtac gtaatatttg ctactagaga gttaggaaac
      301 atcgggaaca gacatactca acagaaacca aaataaacac gtcagaagat tgcagagcag
      361 gtgaaaacct gctctttttt catgagtcaa cctttagttc cttagttttc ataaggtcct
      421 aaaaatattg aaaggagtat gttttgaaag agttagatca aaaccaagcc ccaatttatg
      481 aggccttggt gaagttacgc aagaaaagga ttgttccctt tgatgttcca ggtcacaagc
      541 gtggacgggg aaatccagaa cttgtcgaac tcttaggaga aaaatgtgta ggcattgatg
      601 tcaattcgat gaaacccttg gataatttag gccatcctat ttcgattatt cgtgatgcag
      661 aggagctggc tgcagatgct tttggagcta gccatgcctt tctaatgatt ggtggaacaa
      721 cttcatcggt gcagactatg attctggcaa cctgcaaggc aggagataag attattctgc
      781 cacgaaatgt ccataaatct gctatcaatg cgttggttct atgtggtgcc attcccatct
      841 atatcgagat gagtgtagat cctaagattg gtatcgcttt aggtcttgaa aatgaccgag
      901 tagcacaggc cataaaggac catccagatg ctaaggctat cctaatcaac aatcctactt
      961 actacggcat ctgttcagac ctaaaggggt tgacagaaat ggctcatgaa gctggcatga
     1021 tggttttagt agatgaagcc catggagcgc atttgcattt cactggtaaa cttccaattt
     1081 ctgctatgga tgcaggagct gatatggcag cagtttccat gcataagtct ggtgggagtt
     1141 tgacacaaag ttcgcttctt ttaatcgggg agcagatgaa ttctgaatac gttcgtcaga
     1201 taattaacct gactcagtct acatctgcct cttacttgtt gatggctagt ttggatattt
     1261 cacgtcgcaa cttggccctt cgtggtaaag agtcgtttga gaaagtcatt gagctatctg
     1321 agtatgcccg ccgtgaaatc aatgctatcg gtggctacta tgcctactca aaagagttaa
     1381 tagacggtgt ttcggtttgc gattttgacg taactaagct gtcagtttac actcagggta
     1441 ttggcttaac aggtatcgag gtttatgacc tcttgcgaga cgaatacgac attcagatcg
     1501 agtttggtga tatcggcaat atcttggcct atatttccat cggcgaccgc atccaagaca
     1561 tcgagcgctt ggttggtgct ctggctgata ttaagagact ctattcaaga gatggaaaag
     1621 atttgatagc aggagaatat attcagcccg agttggtgct gtctccacaa gaagccttct
     1681 attcagagag aaaaagtttg accttagatg agtctgttgg acaggtctgt ggagaatttg
     1741 tcatgtgcta tcctccaggg attcctatct tggctcctgg tgaacgcatt acacgagaaa
     1801 ttgtagacta tatccaattc gccaaggaac gtggttgctc cctccaaggg acggaagatc
     1861 cagaggtcaa tcatatcaac gttattaaga gaaagacaaa ctataagaaa agtcaatagt
     1921 tttatctaaa ctatttctta tttcaatttg atgatttggc gatgatttta gagcacggca
     1981 aaaagccctt gaattagaag cggtcaatcg cttaatttct atcagcttat caaatcctgc
     2041 ctcaatcctt ttctgaggat tagggtagcg tgtcaagagt tggtaggtat attctgaatg
     2101 ctttccaacg attttatcca actcaggaaa gatgatatca agacaacgag tgtattgtac
     2161 tttccaatca gactgttttt cttgagacga tgaatatgtc tagccagtat ttttagttct
     2221 acttgccgat tatcgtgttg aaattgttca cgattggggt cagaaagaag tttaagagcg
     2281 atgccatgag cgtctttctt atccgtttta gtcttgtgaa gtgataatga tttggcaaat
     2341 tccttgatga gcaaaggatt gtaggtgtaa actttatatc cttgttcatg caggaagttc
     2401 agtagattaa aggcataatg tccggtattt tcaagagcga tgagacagtc ttggttgagt
     2461 tgtcgaagag acagatctaa gagttcaaaa ccagctttat tatttgaaaa agtgagtggt
     2521 ttaagaacag tttttcctgg aacattcaag gctgtaacat cgtgtttatt tttagcgaca
     2581 tcaatgccca cataaagcat gggagtacct ccagatgtag tatttcaagt ctacttggtt
     2641 atccacgaat tttttgcctt gttaccttag acgagataaa acgtctatgc gttatcaaac
     2701 tcattaccaa ttgaaacaaa aaactgtggt tagagccttt cggaaatcgt caagcgattg
     2761 gagggaataa actaatccac agtggcttat tccaagtata ccacttgggc tttggcagta
     2821 gctaactgcg ctaaatataa tataaggaga aatagatgga tttatggttt tctgaagttc
     2881 atactccaga tgtcaaattg tctctgagaa cagccaagca actttacgct ggaaaaagtg
     2941 aatggcagga tatcgaagtc ttggatacgc cagcttttgg gaaaatactg attttaaatg
     3001 gccatgtctt gttctcagat gcggatgatt tcgtctacaa tgaaatgacc gttcacgttc
     3061 ccatggctgt ccacccaaat ccaaagaaag tattggttat tgggggtggt gacggcggtg
     3121 ttgcccaagt attaacactc tatcctgaac tggaacaaat cgatatcgtg gaaccggatg
     3181 agatgttggt cgaggtctgt cgtgagtatt tcccagactt tgctgcaggg ctagatgatc
     3241 ctcgtgttac catttactac caaaatgggc tacgcttttt gcgaaactgc gaagatgatt
     3301 acgatattat catcaacgat gcgacagatc catttggcca tacggaagga ctctttacca
     3361 aggaattcta cggcaatagt tatcgagctc tgaaggaaga cggcatcatg atttaccagc
     3421 atgggagtcc cttctttgac gaggatgagt cggcctgccg aagcatgcac cgcaaggtca
     3481 atcaagcctt tccaatcagt cgggtttatc aggcccatat tccaactagc ccagctggct
     3541 attggttgtt tggatttgca tcgaaaaaat accaccctgt caaagatttt gacaaggaag
     3601 gttggaaaaa acgccagctt ttcacagaat actacactgc aaacttacac gtgggatcct
     3661 ttatgttgcc caagtatgtt gaggacattt tagaagaaga ggaaggaaaa aaatgagtcg
     3721 tttactagtt attggttgtg ggggcgttgc ccaagttgct atttcaaaga tttgtcaaga
     3781 tagcgaaaca tttacagaga ttatgattgc tagccgtacc aagtcaaaat gcgatgactt
     3841 gaaagcgaag ctagaaggca aaacaagtac taaaattgaa actgcagcac ttgatgctga
     3901 caaggttgaa gaagtgattg ccctgattga aagctacaaa ccagaagctg ttttgaatgt
     3961 agctctgcct tatcaagatt taaccattat ggatgcttgt ttggcaacag gtgttcacta
     4021 tatcgataca gccaactacg aagcagaaga cacagaagac cctgagtggc gtgctatcta
     4081 cgaaaaacgt tgtaaggaac ttggttttac agcctacttt gactactcat ggcagtgggc
     4141 ttatcaagag aaattcaaag aagcaggctt gactgctctt cttggttctg gttttgaccc
     4201 aggtgtaact agtgtctttt cagcttatgc cctcaaacac tattttgatg aaatccatta
     4261 tatcgacatt ttagactgta atggcggtga ccacggttat ccatttgcaa ccaactttaa
     4321 tccagaaatt aatctccgtg aggtttctgc gccaggttct tactgggaag atgggaaatg
     4381 ggtcgaagtc gaagctatgt ctatcaagcg tgagtatgat ttccctcaag ttggacaaaa
     4441 agatatgtat ctccttcacc atgaagaaat cgaatcattg gccaagaaca ttccaggtgt
     4501 caaacgcatt cgtttcttta tgacttttgg tcaatcttac ttgacgcaca tgaaatgtct
     4561 tgaaaatgtt ggactccttc gtacggatac cattaacttt aacggccaag aaattgttcc
     4621 aattcaattt ttgaaagcct tgcttccaga tcctgctagc cttggcccac gtactgtagg
     4681 taaaaccaat attggatgta tctttacagg tgtcaaagat ggcgttgaaa agactatcta
     4741 catctacaat gtttgcgacc atcaagagtg ctatgcagaa gtcgggtcac aagcaatttc
     4801 atacacgaca ggcgttccag ccatgattgg gacaaaatta gtcatgaacg gaacttggaa
     4861 acaagctgga gtgtataacc ttgaggagtt agatccagat ccattcatgg aagctttgaa
     4921 tgagtatggt ttgccatggg ttgtggttga aaatccacaa atggtggact aatgaagtta
     4981 gaacaagtac caacaccagc ctatgttatt gacttggcca agttagaagc taattgccgc
     5041 attctacaat atgtacaaga agaggccggt tgcaaggtct tgcttgccca gaaggcatat
     5101 tccctctaca aaacttatcc cttgattagc cagtatctat caggtacgac agctagtgga
     5161 ctctatgagg ccaaattggc aagggaagaa tttcctggtg aagtccatgt ttttgcacca
     5221 gctttcaagg atgaggacat ggaggaattg cttgggataa cagaccatat cgtctttaac
     5281 tcagagagac agttgcgtaa gcatggggct cgttgtcgag aggctggtgt cagtgttggt
     5341 ttgcgcctca accctcagtg ttcaactcaa ggagatcacg cgctctatga cccttgtgca
     5401 cctggttctc gctttggagt tactatagac aagattccga gtgatttgct agatttggtt
     5461 gacggacttc attttcatac cctttgcgag cagggagcag atgatttaca aacaactttg
     5521 aaagcagtag aagaacagtt tggtccctac ttacatgagg taaaatggct caatatgggt
     5581 ggtggtcatc atattacaag agaaggttac gatgtggatt tgctgatttc agaaatcaag
     5641 cgtatccgaa aaacttacaa tcttgaaatc tatatcgagc ctggtgaagc cattgcgctt
     5701 aatgcgggtt atttagcaac tgaggtatta gatattgtag aaaacggtat ggaaatcttg
     5761 gttttagacg cctctgcgac ctgccatatg cctgatgtac ttgagatgcc ctatcgtcca
     5821 cctttgagaa atggctttga gtcacaggaa aaagcccata cctacagact ttcttctaat
     5881 acctgtctga ctggcgatgt gattggtgat tatagttttg aaaatccagt ccaaatcgga
     5941 gacagacttt attttcaaga catggccatt tattcttttg tcaaaaataa tacctttaat
     6001 ggtattggat tgccaagtct ctatctcatg gacgaacagg gagactgtag cttactcaaa
     6061 gcttttggct atcaagactt taaagggaga ttatcatgat ggacagtcca aaaaaattag
     6121 gctatcacat gccagcagag tacgaacccc atcatggtac cctcatgata tggccgactc
     6181 gaccaggatc atggcctttt caaggaaagg ctgctaaaag agcatttact cagatcatcg
     6241 agaccatagc agaaggggaa agagtctatc ttttggtgga gcaggcctat ctatctgaag
     6301 cccaatccta tcttggagac aaggttgttt atttagacat tcccaccaat gatgcctggg
     6361 cgcgtgatac tggcccaacc attctcgtca atgataaagg taagaaatta gccgtggatt
     6421 gggcctttaa tgcttgggga ggcacctatg atggtcttta tcaagattat gaagaggatg
     6481 accaagtagc cagtcgtttt gctgaggcct tggaaaggcc tgtctatgat gctaaacctt
     6541 ttgtactgga aggaggcgca atccatagcg atggtcaagg aactattctc gtaactgaaa
     6601 gttgcttgct tagtcctggt cgcaatccta acctgactaa agaggagatt gaaaacacat
     6661 tattagaaag tcttggtgct gaaaaagtta tttggcttcc ttatggtatt tatcaggatg
     6721 aaaccaatga acacgtcgat aatgttgttg cctttgttgg tcctgctgag gttgttttgg
     6781 cttggacaga tgacgaaaat gatccccagt atgccatgtc aaaagcagat ctcgaactct
     6841 tagaacagga aacagatgca aaaggttgtc acttcaccat tcataaattg cctatccctg
     6901 cagttcgaca agttgtgaca gaagaagatt tgccaggcta catctatgaa gaaggagaag
     6961 aagagcgata cgcaggtgaa cgactagcag cttcctacgt aaacttttat atcgccaaca
     7021 aggctgtctt ggttccacag tttgaggatg taaacgacca agtggcctta gatatcctca
     7081 gcaagtgttt cccagaccgt aaagttgtcg gaataccagc cagagatatt ctcttaggtg
     7141 gtggcaatat ccactgtatc acccaacaaa ttccagaata ggagaaaaag atgagaaatg
     7201 taagagttgc aaccattcag atgcaatgcg ctaaggatgt ggcaacaaat atccaaaccg
     7261 cagagcgttt agtacgtcag gctgctgagc aaggagccca aattattctc ttgcccgagt
     7321 tgtttgaaca tccctatttc tgtcaggaac gtcagtatga ctactaccag tatgcccaat
     7381 ctgtagcgga aaatactgcc attcagcatt ttaaggtgat tgccaaggaa ctacaagttg
     7441 ttttaccaat cagtttctat gaaaaagatg gtaatgtctt gtataactct attgccgtca
     7501 ttgatgcaga tgggggagtg ctgggcgttt atcgaaagac ccatatacca gatgaccatt
     7561 attatcaaga aaaattctat ttcacgcctg gtaacactgg tttcaaggtc tggaatactc
     7621 gctatgctaa gattggtatc ggtatctgtt gggatcaatg gttccctgaa acagcccgct
     7681 gtcttgcatt gaatggtgct gaattgctct tttatcctac agctatcggt tcagagccaa
     7741 ttttggatac agatagttgt ggtcactggc aacgtactat gcaagggcac gcagcagcga
     7801 atattgttcc agtcatcgca gccaatcgtt atggtttaga ggaggttact cctagtgagg
     7861 aaaatggcgg acagagttcc agtcttgact tctacggttc ctcctttatg acggatgaaa
     7921 caggagctat tctagaacga gctgaaagac aagaagaagc tgttctgtta gctacttatg
     7981 acctagacaa gggagcaagt gaacgtctaa actggggctt gtttcgagat agaagaccag
     8041 aaatgtatag acaaattaca gattagtgtg ggagaaatga gagattcatt ctgctagact
     8101 aacttcttat tagcaactat aagatactat ggcatctagt aaatcgattt ttatgattcg
     8161 ctattcttgt ctattgatta gtccgtattt taaaatatta gcaaaaaagc aaatagcagt
     8221 aacttctgtc tatttgcttt tcttttttat agaatatatt tctcaatagc acgcgcaacg
     8281 ccgtcttctt cgttgcttga ggtaacggca tccgcaagag atttgacata atcgctggca
     8341 tttcccattg caatcccaag ccctgcaaac tggagcattt cgatatcgtt attagcatcg
     8401 cccatggcca taatctctga ggaatcaatc ttcaaaatct cagctagtcg tgaaagagca
     8461 gtagcctttg tcgttccaag cggcattgct tcataaatga caggctgcga acgaactcca
     8521 ctgaatcgtt ggcaaagctc ttcagcaaaa cgctgctcaa aatcgtctgt ttgttctttt
     8581 gttcctaaaa acataccttg gaacatccgg aactttccac tagtcgcttc ttcaagagaa
     8641 atttcagtca ggtctgaaaa tactagttta gcatcatttt caataacttg attgggtttg
     8701 ccaccgagaa caaaataatg tgactcgtca aaaagtgtca actgaacatc actcttttca
     8761 gcaaggtcat agaggtattc gatgtcagct ggactcagtt ctttccagtc aactagactc
     8821 caatcactgg tctggtgagt tgaacaaccg ttgttaacaa taatatattc gttctggagg
     8881 tcaagctcca gttttttgta gtaggggagg acaccgaaaa gggggcgacc cgtacagaga
     8941 accagtttga cacctttttc aatggctttg tgaatagcag taatgtgagc ttgtgggatt
     9001 tccttggctt cattgaggag ggtgccgtcc atatccaagg ctagtagttt aatcataggt
     9061 cttccttctt tatcttttgc tattattata gcatattttg gagaagaaat tgatagaaag
     9121 cttgagacta attgatttta tagtttaaga tgttttgatg acaattcatg atttgaagag
     9181 gatatttggc aaagatatgc tatactatgt ttgtcaatgt tgcaactaga caaattaaaa
     9241 aac
//
LOCUS       DAVKBK010000066         9223 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVKBK010000066 DAVKBK010000000
VERSION     DAVKBK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.066"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(101..2659)
                     /locus_tag="VWX69_001747"
     CDS             complement(101..2659)
                     /locus_tag="VWX69_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9193051.1"
                     /translation="MERSQFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKNFINE
                     QGKIQYFPSYDYGWKQLPPEKRSFQTLTNSVLKSHFRGEAAIGIFPMHLDDSCYFLVL
                     DLDEGDWKEAGLTIRRIARERQMEAHLEISRSGYGLHIWFFFEEAILSRKARLFGKKL
                     LELAMQESMQLSFDSFDRMFPNQDVLPKGGFDNLISLPFQGEAYHQGRTVFVDEQFQP
                     YEDQWRYLQEIQKISTAKVALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFF
                     LKNMASFSNPEFYLKQAMRQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSV
                     EDRRKVQRSISVEFKGELTFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKT
                     KTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKL
                     VDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPE
                     RKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWI
                     ATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDGCYIISGKTKV
                     RERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIH
                     RNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKV
                     LREDLAGERQECLLILPYVHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKI
                     KVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            3207..4407
                     /locus_tag="VWX69_001748"
                     /pseudo
     CDS             3207..4407
                     /locus_tag="VWX69_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4522..5325)
                     /locus_tag="VWX69_001749"
     CDS             complement(4522..5325)
                     /locus_tag="VWX69_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU9193052.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(5606..6361)
                     /locus_tag="VWX69_001750"
     CDS             complement(5606..6361)
                     /locus_tag="VWX69_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU9193053.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCFSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPCFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(6431..9082)
                     /locus_tag="VWX69_001751"
     CDS             complement(6431..9082)
                     /locus_tag="VWX69_001751"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU9193054.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(9094..>9223)
                     /locus_tag="VWX69_001752"
     CDS             complement(9094..>9223)
                     /locus_tag="VWX69_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEU9193055.1"
                     /translation="KYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
BASE COUNT         2825 a         2016 c         1606 g         2776 t
ORIGIN      
        1 acttgtagaa atttttttat tttgtgtgct tcgaatgtga taatgtcaac agtctcatta
       61 aaaaatgaaa atcatacata gaaattttta aaaattttct ctatcgtaaa cctgccacta
      121 gttcagaaac tatactagct gattccaaac gtaatatggt catctcatct accttcccta
      181 ataatggcat tgcaccatac caaacaatag tcttattcac caaaagaata ggcgttacta
      241 tttttgattg agtaaaagac actttaattt tctggctctt caactggtct agccatgctt
      301 tatttgcaac cgtctctggt atacatatct caatttgact aatcctaaat tcttttagaa
      361 aattcatcag ttttgtctgg tgcacataag gtaaaataag cagacattcc tgtctttccc
      421 ctgctaagtc ctctctcaac accttctcat atctactatc aacataaacg aattgtttct
      481 cctcaccctc gatgacacga taatccatct ttcgataagc tacttgtcgt ttctgaaaca
      541 tcttttctaa ataaggaaca tgaatatcca cataatcgaa aatacgcacc aaagacttat
      601 ccttgtagtt tctatgaatc cgacctgcat actgaattaa attatttttc caagaaaagg
      661 gtgctgccaa gataagcgtg tccaactgag gtaagtcaaa accttcgcca atgtattttc
      721 cagtagacaa caaaacaaac cctttatcta actgttctaa cgtctccagt aaactcgttc
      781 tttctcggac tttggttttt ccgctaataa tgtaacagcc atcaacctct ttctctttca
      841 ataacttttc aaagacatct atctgttgaa ttcgattaac taaaaccaag atattccgtc
      901 cttctgccac ttgggctaga atatccttga gaatcaactg attcctcgct gagtctgtag
      961 caatccaatc actgagctgt ataaaattac ttgctttggt cttttcaatc tccaaatgac
     1021 caaaagaagt gaatcttaat tgcaattgcc gtttaaaatc cgtttccctc ttatcagcag
     1081 tatggagtat ctcaccaatt ctctgaaaaa caataggctc atgaccattc ttacgctcag
     1141 gcgtagccgt caaaccgtaa agatacttcc ctctaaactg agcaacaact ttttcaaaca
     1201 tcaaggcaga gacatgatga cactcatcca caatcatcat ctcatactca tccaaaagac
     1261 tttgactatt ttccaactta aatagagatt gaatcataac gacatcaacc agtttactca
     1321 gccatttctt agtcccaccg tactgtccaa catagccgat taccttttca cgacctgatg
     1381 ccgtataacg gatagcctcc tcctcttcga aagtcaaaaa gcagtttaag cgatctagcc
     1441 attggtctaa gagttgctta ttatggacta gaataattgt ttttgttttc cgttcagaga
     1501 taagagcagc acctaaaacg gtcttcccaa aaccagtctc cgcatgaagt aaaccatttt
     1561 ctttagaagt catatctgac agggctaact cttgctcaaa agtgagttct cccttaaatt
     1621 ccacgctaat agacctttgt acctttctcc tatcttccac agatacctgc ttaaatttat
     1681 cttgcaatgg atacagcaaa cctcttggca accataaata atgatcggat tctccaaata
     1741 aatacattct ctcaggaatt tgataggttg gctgtcgcat agcctgcttt aaataaaatt
     1801 cgggattaga aaatgaagcc atatttttca agaaaaacag tgtcttgggt gtcacagacg
     1861 atttttcaag ttggatcata ttggataaga cgatcttcaa ctccttgtcc aattcttgct
     1921 tgcctaactc ctcttggatt aacagtgcca ctttagcagt tgaaatcttc tgaatttctt
     1981 gtagatacct ccattgatct tcataaggct gaaactgttc atccacaaag accgttcgcc
     2041 cttgatgata agcttctcct tgaaaaggaa gggaaattaa attatcaaat ccacctttag
     2101 gaagaacatc ctgatttgga aacatgcgat caaaagaatc aaaggacagt tgcatacttt
     2161 cctgcatagc caattctaat agtttctttc caaacaggcg agcctttcga ctcagaatcg
     2221 cttcctcaaa gaagaaccaa atatggagtc cgtaacccga acgagaaatc tctaaatggg
     2281 cttccatctg gcgttccctg gctattcttc gaatggttaa accagcttct ttccaatctc
     2341 cttcatccaa atccagtacc aaaaaataac agctatcatc taagtgcata ggaaagatac
     2401 cgatagctgc ctccccacga aaatgagatt tcaaaacgga gttcgtcaat gtctggaaac
     2461 tccgtttttc aggtggcaac tgcttccaac cataatcata ggaaggaaaa tactgaattt
     2521 tcccttgttc attgataaaa ttcttagcat aaacatcata acggccagca aacacagagg
     2581 taaacaattg taatttttct tgcgtcgtca agcgactact ttgaagttgg aacatctcct
     2641 cgaactgaga gcgttccata acaaactgac tcttgtcttt aagacgttta tagtggaatg
     2701 aaataagata tgaacaaatt gattaggaaa atcaaattaa tttatagaaa tcttttagca
     2761 gtcatggcgt cctattccag attcaaaatg ctatacacaa gaaaaactca ctatccccat
     2821 taaaagaaga aaagacatca aggacttcta ccacaattcc atccaaagac acaaaaacag
     2881 ccataagagt cacctccttg attcctatag gctgattata acaagactgg ctgaaattgt
     2941 acatgaaaat aaaatcctaa tagtactcat tttgtatgtg actaatattc cgtctcgctc
     3001 cagaaggtac gaagtaaata gagtttaaac gagcagtcta taaaattcaa aaaacgcata
     3061 ttatcaagcg acctaaaact ttgggctcta taatatttgt agtgggtaaa ttccctatgg
     3121 atattatgga gcctattttg ggtagaaaaa aagtcccata agatctataa tgaaaagcga
     3181 caaaacaact cattagaaag aatcatatgg aacaattaca ttttatcaca aaattactag
     3241 acattaaaga ccctataaaa ttccttacct tgaaacgact ggtatgccta ctagaattct
     3301 ccttagaaaa cgtcgtttta agtgctatca ttgcttgaaa atgatggtcg ctgaaacttc
     3361 tatcatcaag aaaaatcacc aaattcctcg tattatcaac caaaagattg cgcaaaagtt
     3421 aattgaaaag atttctatga ccgatattgc ccatcagctg gccatttcaa cttcaactgt
     3481 cattcgaaag ctcaatgact tccactttga gtgtaatttt agaaatctgc ctaagattat
     3541 gtcttgggac gttgaaacag tccggggagt gactgtttca atcgggagat ggagatgagc
     3601 tttattgcgc aagattttga aaagctcgat atcatcactg ttcttgaggg tagaacacaa
     3661 gctgtcatcc gagatcactt tcttaaatat gatagagccg tccgatgtcg cgtcaaaatt
     3721 attactatgg atatgtttag tccttactat gacttagcta aacagcttcg ctttcaaatt
     3781 tctaggctca ggctgaaaca gtctcccaga ctgtttcact cccgaatgct aaaatcgttc
     3841 ttgatcgctt tcatattgta caacatctta gccgtgctat gagtcgtgtg cgtgtccaaa
     3901 tcatgaatca gtttcatcga aaatcccatg aatacaaggc tatcaagcgc tactggaaac
     3961 tcattcaaca ggatagccgt aaactcagcg ataaacattt ttatcgccct acttttcgta
     4021 tgcatttaac caataaagag attttagaca agcttttgag ctattcacaa gacttgaaac
     4081 atcactatca gctctatcaa ctcttgctgt ttcactttca gaataaggaa ccggagaaat
     4141 ttttcgaact tatcgaggac aatcttaagc aggttcatcc tatttttcag actgtcttta
     4201 aaaccttcct caaagataaa gaaaaggtta tcaacgccct tcaactacac tattctaatg
     4261 ccaaactgga agcgaccaat aatctcatca aacttatcaa gcgcaatgcc tttggttttc
     4321 gaaactttga aaacttcaaa aaaacggatt tttatcgctc tgaacatcaa aaaagaaagg
     4381 acgaaatttg tcctttctcg aacttagctt ttcttcaacc cactacaatt gacaaagagc
     4441 caaactttga tgatatacgt tttcttgtga gaatatttac ttcatttttg cctaaaattc
     4501 aatgtttact cagtatttgg attatgaaaa atcaaggtct aaatctagat acattttttc
     4561 tgaagacaaa tcattttgac caccgagcaa gagattttca aaaaaagctg ttaaaaactc
     4621 aggacgtcgc tgtaaaatct ttgcattatc taataccaag gcatcacgaa aatatttgga
     4681 atgttgctga aatggtgtat tatcaatatc aaaaccaaac tcacgaagat actgaatcaa
     4741 aaagaccgtt actgtccgag tgtttccttc gcgaaatgga tgaatctgcc agattcctga
     4801 aataaaatgc tggatttgtt taaccacatc cgcctgagtt agtgtcgcat atgcaacttg
     4861 tttttcctga ttaaaatcat aatctaaggt catttgaatc atggagtaat cagagtacac
     4921 aacactttca ccattcaaaa caggttcatt ctttgtgata ttggtctgac gaaattgccc
     4981 caccggaata gagggttcaa atatatcttg aaacaactcc ttatgaatag caagtaaggt
     5041 cgcaggacta aagctaaagc ctcttcgaga caatagttct acaatacgta gagaaaccaa
     5101 gtctgcctct tccgtacttg catcaatagt atggtgataa gccgttgcat cctcataaac
     5161 ctgctcataa gtcagttctc cccgggactg tttctcagcc aaagattcca tatacgctga
     5221 tggcactaga ttgtcaactt tctgcagacc aaaacctatc cgccataaat cacgcttcgc
     5281 ttcataagac aagtttggat tgtcaatgtt gtaagttggt tgcatagaaa tatcctttca
     5341 attgtttttc ttcattacca gtaaatcacg aaattggttg gaaactggct taaactataa
     5401 aaagtcctca caataggttc tatgatatat atatatatat acttcatgta aataataaaa
     5461 gagttataat cagcactact gataaattca ataccgattt cgccatctta aaacttagtc
     5521 aaacgaatac cgttgatttc cagttcatta agtcgttgac ctgtcaagac ttctcgttcc
     5581 ttcaactgga aaagttaagg gggaactaat acaaatcctc tacgcttcta tattcaatga
     5641 tttcattttt gataatattc tttttaaact caaaatgttt taaaggatta tcgattaaca
     5701 ctaactttgg aatatcatct agatttgtga ccaaggataa aataaaatcc gattgaaact
     5761 ccttgacttt ttcaaattct tttgcagtta aacgcacacg ccccttagat tttcggatac
     5821 cttttacttc ggcaaggtaa gaatactctt ggacatctac ctgaaagtca tatccatcac
     5881 cataaagacg ggcatcggtt aactgtccac cttggaattt ttcttcttta tcaaaatgaa
     5941 ggataaaata attctcagcc tccattcccg tttcctgtag acgtttgaat ttagttcgaa
     6001 ctattggttt ttcaacgatg gttatgcctg ttttcttccc ttcactggca agtaacattt
     6061 taactatttc agcataacta tgaacatctt catttccaaa catcatatca attaaatctt
     6121 tacgaaaacg ataaacttca gctttctgcc accaaccttt tcgattattg tcaaaacaag
     6181 gatcaaataa atccattcta ttttttacaa ctccagttgt ttcagcaatt cccagagaaa
     6241 ccacatagcg ataaaactcc gacttgctaa agcattgaaa ttcttttata aaaagcttgt
     6301 caaacttggc aagaccgtag ccaattaaat ttaacaattc ataatgaggg tgtttggaca
     6361 tcactttctc catcaataga tattgatttc attataccaa aaaacacggc tcatcaccgt
     6421 gtttctgtgt ttatttcacc aacttcttca tctcatcaat acgtgctacg gtcacatcat
     6481 acttggcttg gtagtcggct tgtttgtctt tttctttttg gacaacttct ggtttagcgt
     6541 tggcgacgaa gcgttcgtta gagagtttct taccaaccat gtccagttct ttttgccatt
     6601 tagcgagttc tttgtcgaga cgagctagtt cttcttcaac attgaggaga tcggccagtg
     6661 gcaagaagat ttcggctcct gtaataacgc ttgacatagc cagttcaggt gcagggatgg
     6721 ttgatgcgat ttccaagtgt tctggatttg taaagcgttt gatatagttg acattgctgt
     6781 taaagaaggc ttccaagtca ctatcgcttg tcttaacaag gatggtgata ggcttgcttg
     6841 gtgctacatt tacttccgca cgcgcattcc gaacagcacg aattaagtct ttgagacttt
     6901 ccacaccagt gtgagccgca aggtcttcaa aggctagatt aacagttggg tatgcagctg
     6961 tcacgataga accttctgag atttgtccaa agatttcctc tgtcacgaat ggcatgattg
     7021 ggtgaaggag acgaaggatc ttgtccaaag tgtatagtag aacagaacgt gtgatgactt
     7081 tctcttcttc gttatcgcta taaaggactt ccttggtcaa ctcaacatac cagttggcaa
     7141 attcttccca aatgaagttg taaaggatat gaccagccac accaaactcg aacttatcaa
     7201 agttttcagt aacttttgca atggtttcgt tgagattgtg gagaatccag cggtccgtca
     7261 cattaccagc ctcacctgtt gcaacttttg tgacattgtc atgcgccaca tccagcgtca
     7321 aacctccatt gttcatgagg atatagcgag aaatgttcca aatcttgtta ataaagttcc
     7381 atgaagcatc cattttctca taagagaaac gcacgtcttg tcctggcgca gaaccgtttg
     7441 aaaggaacca tcgaagggca tcggcaccgt atttctcgat aacatccatt gggtcaatcc
     7501 cgttaccgag agacttagac atcttgcgtc cttgctcgtc acgaatgaga ccgtggataa
     7561 ggacgttttg gaatggttga cggcctgtga attccaatga ctggaagatc atacgagaca
     7621 cccagaagaa gatgatgtcg taacctgtta ccaaggttga agttgggaaa taacgtttaa
     7681 agtcttctga gtcgacttca ggccagccca tggttgaaaa tggccagagg gcagaactga
     7741 accaagtatc caagacgtct tcgtcctgag tccatccgtc accttctgga gcttcttcgc
     7801 cgacatacat ttcaccatca gcattgtacc aggcagggat ttggtgaccc caccaaagct
     7861 gacgagagat aacccagtcg tggacatttt ccatccattg aaggaaggta tcgttgaaac
     7921 gaggtgggta gaattcgacc ttgtcctctg tgtcttggtt ggcaatggcg ttcttagcca
     7981 attggtccat cttgacgaac cattgagtag acaagcgtgg ctcaactacg acacctgtcc
     8041 gttctgagtg accgactgaa tggacacgtt tttcgatttt gacaagggca ccgatttctt
     8101 ccaacttagc aacgactgcc ttacgagctt caaaacgatc catgcctgaa aattcaaagg
     8161 caagctcatt catagttccg tcgtcgttca tgacgttgac ttgtggcaag ttatgacgtt
     8221 ggccaaccaa gaagtcattt ggatcgtggg caggtgtgat tttcacgaca ccagtaccaa
     8281 actcaggatc tgcgtgctca tctccaacga ttgggatgag tttattagcg attggaagga
     8341 tgacgttttt accaatcaag tccttgtagc gcgggtcttc tggattaacc gcaaccgcaa
     8401 cgtccccaaa catagtctca ggacgagttg tagcaacttc aagggcgcgt gaaccatctt
     8461 ccagcatgta attcatgtgg tagaaggcac cttctacatc cttgtgaatc acctcaatat
     8521 cagaaagggc tgtgcgagct gctgggtccc agttgatgat aaactcacca cgatagatcc
     8581 agcctttctt gtaaaggtcc acaaagacct tacgaacagc ttttgacaaa ccttcgtcaa
     8641 gagtgaaacg ctcacgagaa tagtctacag aaagccccat cttgccccat tgttccttga
     8701 tggtagtggc atattcgtct ttccattccc agaccttcgt caagaaagac tcacgaccta
     8761 ggtcataacg cgtaataccc tcaccacgta agcgctcctc aaccttagcc tgagtcgcaa
     8821 taccagcgtg gtccatacct ggaagccaaa gggtatcaaa gccctgcatg cgtttttgac
     8881 ggatgatgat atcctgcaaa gtcgtatccc aagcgtgacc aaggtgaagt ttcccagtta
     8941 cgtttggtgg tggaatcacg attgaataag gcttagcctt ttgatcgcct gaaggcttga
     9001 aaacatccgc atcaagccat ttttggtaac gaccagcctc aacctcggct ggattgtatt
     9061 tagatgaaag ttctttagac atgtgtgttc tccttaatta cttttattga caattttaac
     9121 caaaccaatt tttgaaagtt caatataaat ctcttcaatt tcagcaaatg ctgcaagtgg
     9181 tgacatagta taatttccag gattatattt aagatcatac ttg
//
LOCUS       DAVKBK010000067         9068 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVKBK010000067 DAVKBK010000000
VERSION     DAVKBK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9068
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.067"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(406..2685)
                     /gene="pulA"
                     /locus_tag="VWX69_001753"
     CDS             complement(406..2685)
                     /gene="pulA"
                     /locus_tag="VWX69_001753"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU9193056.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(2797..4755)
                     /gene="ligA"
                     /locus_tag="VWX69_001754"
     CDS             complement(2797..4755)
                     /gene="ligA"
                     /locus_tag="VWX69_001754"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU9193057.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(4848..6026)
                     /locus_tag="VWX69_001755"
     CDS             complement(4848..6026)
                     /locus_tag="VWX69_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9193058.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(6106..6969)
                     /locus_tag="VWX69_001756"
     CDS             complement(6106..6969)
                     /locus_tag="VWX69_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9193059.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQKAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(6972..8873)
                     /locus_tag="VWX69_001757"
     CDS             complement(6972..8873)
                     /locus_tag="VWX69_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9193060.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         2733 a         1996 c         1622 g         2717 t
ORIGIN      
        1 tacgtcaagg cgaggctaat gtggtttgaa gaaattttcg aagagcgtga atgagtatca
       61 tctatagtaa aataaaaaaa ctgaacaatt tggttgggga cagccaaacc aatttctcac
      121 aatgtttcag aaacaagggt gtgctactcc aatttcagcc tactataact gtcatagatt
      181 gctgaaacaa agtctaggta aaagtcttca taataaaaag acctcctatc aagtgttcaa
      241 aaactttgat aggaggtctt gttttgtgaa aatatttatc aaattttcta tacaagtgag
      301 ctgttagcca ggttctttct attctttcaa tttcaatgaa tggatttttt actaatactc
      361 ataactggga atttgtctgt gtaaaaatag cgagatagat ggtatttata aaacactcaa
      421 gacagctaga ctaatatcat ttaaaacatt atcttctttt gagcgactgt tggttaccaa
      481 catagctaaa tttcctgcat tttcaaattg atagggttct gatttagcat tcacaaccac
      541 caagaggtgt tctttgccgt gaacttcata gataaggtag ccgctatgtt caatcgcaga
      601 atgcacaaag acatgatggt aaatttcatc atagctagag taagaaaagg caccagtttt
      661 tgtcttcaat cggatgactt gacggataaa ctcaatactg tcttgacgct cattaatcaa
      721 gttccagttc acttggttca cactgtcagg agcattatag ctattcatcg cacgctctct
      781 atcatcatgg gtcaactcac cattttcacc agtcgcaacc agtttggtac gaccaaattc
      841 ttgaccgatt tccataaagg ccatcccctg catgagcaga ttcatggctg tggcagtttc
      901 gaccttgcgc atgatttgct ctgaactttg gtctggatga agggttgcca ataaatcgtg
      961 aagattgtaa ttgtcatggg cttctacata gttaagcacc tgatttggat gtgtatagct
     1021 tcctaattca cgacttccta ggattgcttt agctagaatt ggctctgtcg cagcaccact
     1081 gacaaaacct gacttgatag caccataaac ttctccccct ttgacagcat cgcgctgatt
     1141 gtcattaaag aaaccaatat ttggcatctg gtaggcattg tccttcttgg ccttatcata
     1201 aggggcaaga cctgttccca tatcccatcc ttctccatag aggataatgt tggagtcgat
     1261 ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca tcatgaatcc ccatcaagtc
     1321 aaaacggaag ccgtcaatat tatattcctg cacccagtat agaagagaat caatcatata
     1381 cttgcgaaac atttcgtgtt cactggctgt ttcatttcca acacccgttc cattctggaa
     1441 ggtaccatct ggattcatac gataatagta atcagggact gttgtttgga atggtgcatc
     1501 aacaactgag aaggtatggt tatagactac atccataatg actccaatac ccgcatcgtg
     1561 ataagcttga accatcacct tcaaatcacg aatgacctga gctggatcat ctggattagt
     1621 tgaaaaacta gtttctggcg cgttatagtt ttgtggatca taaccccagt tgtaggttac
     1681 atttccatcc tcatcgtatt ctttatgacg gtctgcaatt ggttgcaatt gaacataatt
     1741 gtagcccagc ttcttgatgt aatcaaaagc agttgactgg ccgtattggt taactgttcc
     1801 agcctgagca gcacccaaga aagttcctcg aagatgttca tctacacccg atgtaggtga
     1861 tttagtcaaa tcacgaatat gcatttcaca gataactgcc ttacatggat tttccaagcg
     1921 ccaagtagcc tccgaaccgt gcttaacctc gaagttttca acttgctttt ctacatggct
     1981 cagaatagct gaacgtttgc catcagggct ggtcgcgatt gtataaggat cacgtgtcag
     2041 tgtttggtga tgagggaatt ggacttgata ctgataagcc ttacctacca aatcttcctc
     2101 aacatccaaa ctccagacac cgattgtatt gtccttatga ttataagagt agctattgcc
     2161 tcttttcatc tcaaaagtct tccaaacggg tgcatcatta gcagctgatt cataaacgac
     2221 aacttgcact tctgtcgctg taggtgacca gagggaaaaa tgagcctgat tgtcctctac
     2281 acggcaaccc aattctcctt ggtaacccca atgatggtca aaactagcac tgttaatggc
     2341 cttatcaaag gcaaaaggat tttgattttt atagaaagga ctggcaatag caggattttc
     2401 agagtaataa atcctatcat cgccttccaa aatccagacc tctgttaata ggggatagtg
     2461 attaaaacgg atagaatatt ctttactagt ttgacctgta tgaaccacaa aattcaagct
     2521 ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa gctccaaaat aatcttcttt
     2581 gtaggttagc aaatcaattc gttgatcctg actttttaca aaggagcaag tgtcatattc
     2641 tccattctta cgatggtaat gaatgcgcat agggtagtta tacatttttt atttttcctt
     2701 tttactttgt ttctatttca ctaataaatt tttgtcaatc tcgtctcaat taacagacat
     2761 agtcatattc tctaaactct gtttttaaac gatccattac aaactttcta gccatgcctc
     2821 atctctgacc tggataccaa gttcttgtgc tttttgcagt ttacttccag cgtctgcacc
     2881 taccacgacg aggtcggtct ttttagaaat actacctgtc actttggcac ccagactttc
     2941 gagtttactt ttagcttctg agcgcttgag tcgttccaat tttcctgtca ataccacggt
     3001 caaacctgac aaggccgcat ccgctactac cgtctgtcct ttatagtcca gattgacccc
     3061 agtttctttc aattctctga gcagaatttc agagccttct gtcgcaaaat aagtctgaag
     3121 acttttggca atcacgccac ctagactttc aatactagcc acttcctctg aatctgcctg
     3181 agacagattt tcaattgaat ggaaatattg aagtaaaagc tgactaacct tgcttccgac
     3241 atgacgaatt cccaaaccaa ataagagctt ctcggcagaa ttttcctttg atgcttggat
     3301 agcctgatac agtttagcag cggacttttc cttaaccccc tctaaaagga ggaaatcctc
     3361 ttcttgcaaa cgataaatat ccgccacatc cttgactaaa ttagcagcaa aaagcttctc
     3421 aacaatagat ggaccaaggc ctgtaatatt catagcatca cgagaagcaa agtgaatcaa
     3481 gccttccatg atttgagcag ggcaacgcgg attgatacaa cgtagggcca cttcatcttc
     3541 aaagtgcaac aagtcagagt tacaacttgg acagtttgta gggatatcta gtttttcttc
     3601 agaaacccgt ttggactcta ccacacgtaa aacggcaggg atgatgtcac cagccttata
     3661 tacaatgacc gtatcgtctt ttcggatatc tttttcagca atataatcta cattgtgcag
     3721 ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt gttagattag cagttggagt
     3781 tacaacaccg gtacggccaa ctgtccagtc aactgataag agttgagctt ctttttcttc
     3841 ggcagggaac ttgtaggcta ctgcccactt tggagcctta actgtaaaac caagttcttc
     3901 ttgacttgct aggtcgttga ccttgattac cactccatca atatcgtaag gcagattttc
     3961 ccgttcctgt cctacttctt ggataaaatt ccagatttca tctatgtttt cagccaagat
     4021 tcgcttagga ttgaccacaa aacctagttg ttctaggtac ttcaaaccct tttcttggct
     4081 atcacgagtt gaagggctgg cttcttgata gagaaacgtt gcaagattac gcttggcaac
     4141 tactgctgta tccaactgac gcagagttcc tgctgccgca ttacgaggat tagcaaattc
     4201 aggctctcca ttttcttggc gcacttggtt aacttggtca aaggaagcgc gtggcatgta
     4261 acattcccca cgaactgtga tatctagttc ttctggcaaa gtcaaaggga tgtccttaac
     4321 acgcttgagg ttttctgtga tattttcacc aattgaacca tctccacgtg ttaccccagc
     4381 aaccaaaatc cccttttcat aagtcagcga gatagataag ccatcgattt tcagctcaca
     4441 aatataggtc ggatgagcca cttccttacg aacacgcgca tcaaaagcat ctagctcctc
     4501 acgtgaaaaa gcatcctgca aactataaag aggatactga tgactgtatt tttcaaaacc
     4561 atctaaaacc ttgccaccaa cacgatgagt cggactgtct gctagcactt gctctggata
     4621 agcagtttct aactcgacca actcacggta aaggcggtca tactcactgt ctgcaaccga
     4681 gggattatcg ctggtatagt actcagtcgc atagcgattg agcaaagcga ctaactcatt
     4741 cattctttta ttcataagac cattttacca taaaacaagc cctcctcaca aacgagaagg
     4801 gcggaaaaaa cacttagttt gaaattattt ttgaaactca agcaacctta tatcaatttt
     4861 tcaaaatgag ttcgaacata aataaacgat atacaagaca agatgataac accacttcca
     4921 attatcagga aagaagagag atgtacactt ggcaagactg tcataaatcc ttttgcaata
     4981 ggcataaata gaatagctaa ggtaaaaatt gtactcagta ctcttccaag aaattcgctc
     5041 tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa aaatcgtcat aaacaattca
     5101 caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg gtaatcccat cataaaaact
     5161 ccgacacctg tcaaagccag taaaatcaaa agattataaa tattagcttt aattttacta
     5221 gctagaagag ccccaatgat ggaaccaata gcccccatag ttaaaatact tgcataggct
     5281 ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc tgcaaaaaag
     5341 aaattaacgc tggaagctac cagcaaaagg aagaaaattt cttgctgatg ccagatatag
     5401 tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt tttctcttga
     5461 acttttgctt cctcttttgg aaggaaagcc actagaacaa aagcaatgaa aaaagtcagc
     5521 gagtctagca gtagcgtcat attgagactt gcaaactgta aaacaaggaa ggaaagaaca
     5581 ggagagctaa cacctacaac ctgcaaaacc agctctaagc gagaattata gatcacaatc
     5641 tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga aaaggcaaaa
     5701 gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct atcattcctt
     5761 atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat taaaatctta
     5821 cgacgagaaa aacggtctga aataactccg ccaaagggat tgacgagaat agatgtgacg
     5881 agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat agaagccaac
     5941 cagacactat ttccataatc atagagcata tttcccattt tattgatagc cccacggcta
     6001 atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga aactattgta
     6061 tcaaaaccga aaggagcttt ttattttttc ccttatttgg gaaaattaac ttttgacaaa
     6121 tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca catcaaaaat
     6181 atgcatggcc ttttgcatct gcttacagcc ttctttacac tgtccttttt gatataaggc
     6241 aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt tgtcaataat
     6301 cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatgct ctaaacaatg
     6361 ctggtaacaa ttgagggcca aaatcaaaac taatctctta tggcgactaa tctcttggta
     6421 aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta catcgtagaa
     6481 actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg ttttgaagag
     6541 ataatctgct accttatcca aatcatcctg cttcatatca taagtcgcat ctctttgaca
     6601 aatcagacct tgtagcaaaa tccagttcag ctcaaaataa agggaagtcg tcgaactctt
     6661 agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt ttgaatagta
     6721 aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat tccttgcctt
     6781 atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga aacgggagac
     6841 tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc aggattcgcc
     6901 tgctgcttcc tttaaagaat aatttccact tgttcgaaat tcacgaaata cttttccaag
     6961 atgttccatc tttacacctg atctgataat tcttcccact caagcatagc ttcttcctga
     7021 cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc atcgtttgtt
     7081 tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat ttcagcttct
     7141 agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt ctgggcctga
     7201 tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc ctcagtctga
     7261 ctcatttctg ctgttgcttt cttctcaaca tagtagtcgt aatctccaag gtagagagtt
     7321 gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa gtaacgatca
     7381 tgactgacaa aaagcaaggt accatcaaag tcaatcaagg cattttctag cacttcctta
     7441 ctatcaatat ccaagtggtt ggtcggctca tccagaatca aaaagttatt gttttccata
     7501 gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc gactgatttt
     7561 ttaacatcat ctcctgagaa aaggaaggcc ccaagacggt tgcggatttc aacttctggt
     7621 gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt cagcttgctt
     7681 tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc acctttgata
     7741 aaaggaatct ggtccacaat agacttgata aaggttgact tgccgatacc atttggacca
     7801 acgatagcga cagcattcat cttacgaaga tctaggttga taggttgtga caaaacttcc
     7861 ccgtcataac caatagcagt attttcaaca gtcaaaacaa cattgcccga cgttttttca
     7921 gactggaagg tcatgttggc tgctttcttg ccagcttcag gcttgtccaa acgctccatt
     7981 ttttctagtt gtttacggcg agattgagca cgtttggtcg ttgaagcacg aactagattg
     8041 cgattgacaa agtcttccag agcagcgatt tccttctgtt gcttttcata gttttttgcc
     8101 tcagtagcta gcttttgctc cttcaactca acaaaacgag agtaattccc cacatagcga
     8161 tccaaggaat acttggtcaa atctagcgta attgtcgcaa ccttgtccaa gaaataacgg
     8221 tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc tagccaggag
     8281 atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt gggcttttca
     8341 aggagcattt tagctagagc caaacgagta ttttgaccac cagaaagctc agcaattttc
     8401 atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat atcagcttca
     8461 taggtaaagc cacctgcttg gcgaaaattt tcagataagc ggtcataatc tgacatcagt
     8521 ttatccaaat cctcaccaga cttttcaccc atctccagct ccatctgacg cagttgttta
     8581 tctgtccgac gtaagtcatc aaagacatga agcatctcat catagatggt attttcagac
     8641 tcaaaacggc tatcttgagc taggtaagac agagaaatat cttttttctt attgatttct
     8701 ccactagttg gctcctcttc tccaactaaa atcttcaaaa gagtagactt acctgcacca
     8761 tttttcccaa caagggcaat ccgatctcgt tcatcaacct gcaggttgat attatcgaaa
     8821 agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat catacaagta
     8881 gtatagcatg tttccctaag gcattcaaga taatcgtaag tcttttagta caacttttat
     8941 aacataaaat aaactaaatt atgtatattt tatattagat tccttcacta tcttgttgga
     9001 ttttctaacc agctaatctt gtttcaaata gttatcgcac aagcctatta tttaattctt
     9061 ttcattat
//
LOCUS       DAVKBK010000068         8926 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVKBK010000068 DAVKBK010000000
VERSION     DAVKBK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.068"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..415)
                     /locus_tag="VWX69_001758"
     CDS             complement(<1..415)
                     /locus_tag="VWX69_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEU9193061.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVD"
     gene            537..1283
                     /locus_tag="VWX69_001759"
     CDS             537..1283
                     /locus_tag="VWX69_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9193062.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1296..2276
                     /locus_tag="VWX69_001760"
     CDS             1296..2276
                     /locus_tag="VWX69_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU9193063.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            2471..2791
                     /locus_tag="VWX69_001761"
     CDS             2471..2791
                     /locus_tag="VWX69_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9193064.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            2837..3145
                     /locus_tag="VWX69_001762"
     CDS             2837..3145
                     /locus_tag="VWX69_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9193065.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3162..4460
                     /locus_tag="VWX69_001763"
     CDS             3162..4460
                     /locus_tag="VWX69_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9193066.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            4611..7049
                     /locus_tag="VWX69_001764"
     CDS             4611..7049
                     /locus_tag="VWX69_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU9193067.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7068..7736
                     /locus_tag="VWX69_001765"
     CDS             7068..7736
                     /locus_tag="VWX69_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU9193068.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLVLAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            7754..8842
                     /locus_tag="VWX69_001766"
     CDS             7754..8842
                     /locus_tag="VWX69_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU9193069.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT         2951 a         1252 c         1815 g         2908 t
ORIGIN      
        1 aatccacata ttgaattaaa tcaataaatt tttcatgatc aacaaaggca gtagtttcaa
       61 tggcagtgtg tatgtgatgt tctttagctg attttaagat ggctttagca aattcaaact
      121 gagcaaatat ttcacctcct gataaagtta aacctccacc ggattcttcg taaaattctt
      181 tgtcttttaa tacctctgta ataatttctt ctacagtctt ttcttcaccg actaaggtga
      241 atttctctcg ttgagcatct ttcatttttt caggtttcat tctttgagat tcaggattag
      301 aacaccatgg acagcgcaga ggacatcctt ttaaaaaaac agttgtacga atacccgggc
      361 cgtcatgaat tgaaaagtgt tgaatattaa aaataattcc tttagatatt tccataagag
      421 ttcctcctct tcataagtct atcctatcac aaaaacgaaa gaaaaacaat tacgaacgaa
      481 agtttaattt gttgtttttt gctttttatt ttggtagaat aaaacggagg tgtaaaatga
      541 aaagattgga acaaattatt aaattagtat cagaatatga aaagatcgac gttaatacat
      601 tatcggaaaa attaaatgta tcgaaagtaa cgattagaaa agatttagat aaattagagt
      661 caaaaggttt attacacaga gagcatggat atgctgtatt aaatagtgga gatgacttaa
      721 atgtacgttt gtcaattaac tatgaaatta agagaaaaat tgttcaggaa gcagtaaaat
      781 tggtgtcaga taatgaaaca ataatgatag aatctggatc gacctgtgct ttacttgctg
      841 aggaaatttg caagcaaaaa agaaatgtta cgattgtaac aaattcattt tttatagcaa
      901 attttgtgag agcttatgat tcatgtcgta ttattgttct tggtggagag tttcagaagg
      961 attcacaggt tactgtggga cctttattaa aagaaatgat acagactttt catgtgcatc
     1021 aagcttttgt tgggacagat ggttacgata aagagatggg ctttacagga aaagatttaa
     1081 tgcgcagtga ggtagttcaa tatatttcag cagcgtcgga taaagtcatt gtactaactg
     1141 actcaagtaa atttgataaa aggggtacag taagaagatt tgctttaagt caagtctatg
     1201 aagtaataac agacgaaaaa ctttctaaac aaaatatagc tacattagaa aatgctggga
     1261 taatggttaa ggtagtttcg taagaggtta aatgtatgaa tcaagatagg aataaactgc
     1321 tctctaaaat tgcttatctg tattatattg aaaacttaaa tcagtcacaa atagcagcaa
     1381 aattaggaat ttatagaacc tctattagta gaatgttaac agaagcaagg aatgcaggaa
     1441 ttgttaaaat tgaaatagag aattttgata ccaatatgtt taagttggaa aattatgtaa
     1501 aagaaaaata tggtctggaa agtttagaaa ttattccaaa tgaatttgat gataatccaa
     1561 caattttatc tgaaagaatt tctcaagttg cagcaggtgt ccttaggaat ctaattgatg
     1621 ataatatgaa aattggcttt tcttggggga aaagtttaag taatttagta gatttaattc
     1681 acagtaaaag tgtccgaaat gttcacttct atcctctagc aggtggtcct agtcacatac
     1741 acgctaaata ccatgtgaat acactgattt atgaaatgtc tagaaaattt catggagagt
     1801 gtacatttat gaatgcaacg attgtgcaag aaaataaatt gttagcagat ggtattttgc
     1861 aatcaagata ttttgaaaat ttgaaaaata gttggaaaga tttagatata gctgtagtcg
     1921 gaattggtga ttttagcaat aaaggaaagc atcaatggtt agacatgctt acagaggatg
     1981 actttaaaga attgaccaaa gttaaaactg taggagaaat ttgttgtcga ttttttgatt
     2041 caaaaggtaa agaagtctat gaaaacttac aggaaagaac gatagcaatc tctttggaag
     2101 atttaaaaaa tattcctcaa agtttagctg ttgcttacgg tgatacgaaa gtatcttcga
     2161 ttctttctgt cttgcgtgct aatttagtaa atcatttgat tacagacaaa aatacaattt
     2221 taaaagtttt ggaagaagat ggggatttga cttttagaga gattctaggt gagtgaaaat
     2281 gatagactga tcagtttatc gttttttctt tttagtcgat tgcacatttg tgctcatata
     2341 aacaaaaata gtttatctgt tgtttttgga ttgacaactt tattatgtag ttgtattcta
     2401 tagttacaaa agaaaatttt aaaatttcaa atgaaaaaag ctttttacat agtgaaatga
     2461 ggaggaattt atggaaatta ttgttccaga tcaaattatc atgggtttaa ttttatatgc
     2521 tggtgatgcg aaacaacata tttataaagc gttagattac ataaaaaatg gtacatgtga
     2581 acggtgtgaa gaagaaatcc agttagctga tgccgcctta ttagaagccc ataatctaca
     2641 aacaaaattc ttggcacaag aagcgtctgg tacaaagaca gaaattacag ctctctttgt
     2701 tcattcacaa gatcatctca tgactagtat gacggagatt aatttaatca aagaaattat
     2761 tagtttgaga aaagaacttc ataaaaaata atactagagt attatcattg ttattaacat
     2821 agaggaggaa aacataatgg tgaagattgg tttgttttgt gcagcaggtt tttctactgg
     2881 tatgcttgta aataatatga aaattgcagc gcaagctagt ggagttgagg cagaaataga
     2941 ggcgttttct cagtctaaat tagcggatta tgcgccaaat atagatgttg cactattggg
     3001 tccacaagtt gcttatacat tagataaatc aaaagaaatt tgtgataagt gtgatgttcc
     3061 gatagctgtt attccgatga tggactatgg tatgttagat ggaaaaaaag tattagattt
     3121 ggccctatct ttgattagtg ggtaagaaaa ggagatttat tatggcaaag atggatgttc
     3181 agaaaatcat tgcaccgatg atgaagtttg tgaatatgcg tggcattata gctctaaaag
     3241 atgggatgtt agcaattttg ccattgacag tagttggtag tttattcttg attatgggac
     3301 aattgccgtt cgaaggatta aataagagca ttgctagtgt ttttggagct aattggacag
     3361 agccgtttat gcaagtatat tcaggaactt ttgctattat gggtctaatt tcttgttttt
     3421 caattgccta ttcttatgct aagaatagcg gagtagaggc tttaccagct ggagttctat
     3481 ctgtatctgc attctttatt ttgctaagat catcttatat ccctaaacaa ggtgaggcaa
     3541 ttggggatgc tattagtaaa gtttggtttg gaggtcaagg aattatcggt gctatcatta
     3601 taggtttggt agtaggaagt atttatacct tctttataaa gagaaaaatt gttattaaga
     3661 tgccagaaca agttccacaa gctattgcca aacagtttga agcaatgatt ccagcatttg
     3721 taattttctt actttctatg attgtatata ttttagcgaa gtcattgact aatggcggaa
     3781 cattcataga aatgatttat tctgctattc aagttccatt gcaaggttta actggatctt
     3841 ggtatggtgc aattggaatt gcattcttta tatcattttt gtggtggttt ggtgttcatg
     3901 gacaatcggt agtaaatgga gtagtgacag ctctgctttt atctaatctt gatgctaata
     3961 aagctatgtt agcctctggt aatctatcat tagaaaatgg tgcacatatt gttactcaac
     4021 aatttttaga ttcattttta attctatcag gttcagggat tacgtttggt cttgtagttg
     4081 ccatgctttt tgcagcaaaa tcaaaacaat accaagcctt aggaaaagtt gccgcttttc
     4141 cagcaatatt taacgtaaat gagccagttg tatttggatt tccgattgtc atgaatccag
     4201 ttatgtttgt acctttcatt cttgttcctg tacttgcagc tgtgatagta tatggagcta
     4261 ttgcaacagg tttcatgcag ccattctcag gggtaacatt gccttggagt acaccagcta
     4321 ttttatcagg atttttggtg ggtggatggc aaggagttat tactcagctg gtgatattag
     4381 cgatgtctac attggtttat tttccattct ttaaagtaca ggatcgttta gcttaccaaa
     4441 atgaaatcaa acaatcttag aggtatttgt gtgttactgt taaactcaca catttgtgct
     4501 aaaaattaga gagttaaaat ttttctagtt aaaagcttga aaatttctat aaaaatcggt
     4561 attatatttt cgaaagaaat aaaaatattt tcgaaagaaa ggtggttacg atggtaaata
     4621 cagaagtagc aagaacaaca atcaagacag aatattttgg cagccttact gaaaggatga
     4681 acaaatatcg agaagatgtt ttaaataaaa aaccttatat tgatgctgag agagcagttc
     4741 tagcaacacg cgcctatgaa cgatacaagg aacaacctaa tgtcctaaaa cgtgcatata
     4801 tgctgaaaga aattttggaa aatatgacta tctatattga agaagaatct atgattgggg
     4861 gaaatcaagc ttcttccaat aaagatgctc ctatttttcc ggaatatacg ctagaatttg
     4921 ttctcaatga gttggatctt tttgaaaagc gtgatggaga tgttttctat attacagaag
     4981 aaacaaaaga acaacttaga agtattgctc cgttttggga aaataataat ttacgtgcta
     5041 gagctggtgc cttattacct gaagaagtgt ctgtttatat ggaaacagga ttcttcggta
     5101 tggaaggtaa gatgaattct ggagatgctc acctagcagt taactatcag aaacttttgc
     5161 aatttggctt aagaggtttt gaagagcggg ctcgtaaagc aaaagcagct ctagatttaa
     5221 cagatccagc aagtattgat aaatatcatt tttacgactc tatatttatc gtaatcgatg
     5281 ctattaaagt atatgcaaag cgctttgttg ctcttgctaa aagtttagcc gaaaatgcaa
     5341 atcctaaacg taagaaagaa ttacttgaga ttgcagatat ttgctctaga gtcccatatg
     5401 aaccggcaac tacttttgca gaagctattc aatcagtttg gtttattcaa tgtattttac
     5461 aaattgaatc taatggccac tctctttcat atggccgttt tgatcaatat atgtatccat
     5521 atatgaaggc tgatttagaa agtggtaaag aaacagaaga tagcattgtt gaacgtctga
     5581 caaatctttg gattaagaca attacaatta ataaggttcg cagtcaatca catacatttt
     5641 cttcagcagg aagtccttta tatcaaaatg ttacaattgg tggacagact cgagataaga
     5701 aggatgctgt taacccatta tcttatttgg tattaaaatc agttgcacaa acccatctac
     5761 cgcaacctaa tctaactgta cgttaccatg caggtttaga tgctcgtttc atgaatgagt
     5821 gtattgaagt gatgaaactt ggttttggta tgcctgcatt taataatgat gagattatta
     5881 ttccttcttt tattgcaaaa ggagtattgg aagatgatgc ttatgattac agtgccattg
     5941 gatgtgttga aacggcagtt ccagggaaat ggggctatcg ttgcacaggt atgagttata
     6001 tgaacttccc taaggttcta cttatcacga tgaatgatgg aattgatccg gcttcgggta
     6061 aacggtttgc accaagcttt ggtcatttta aggatatgaa gaacttttct gaattagaaa
     6121 atgcttggga taaaacacta agatatttga cacgaatgag tgttattgtt gaaaattcta
     6181 ttgatttatc attggaacga gaagttcctg atattctatg ttcagcattg actgatgatt
     6241 gtattggtcg tggaaaacac cttaaagaag gtggagcagt atatgattat atatcaggat
     6301 tgcaagttgg aattgcaaat ttgtcggatt cattagctgc aattaaaaaa ttggtgtttg
     6361 aggaagaacg tataagccca agtcagcttt ggcatgcatt ggaaacagat tatgccggag
     6421 aagaaggtaa ggtcattcaa gaaatgttga ttcatgatgc acctaagtat ggtaatgatg
     6481 atgattatgc tgacaaattg gttactgctg cttatgacat ttatgttgat gaaattgcta
     6541 aatatcctaa tacacgttat ggaagagggc ctattggagg aattcgttat tcaggaacat
     6601 cttctatatc agccaacgta gggcagggac gtggaacatt agcaactcca gatggacgca
     6661 acgcgggtac accgttagca gagggttgtt caccatcaca taatatggat caacacggcc
     6721 ctacatctgt tttaaaatct gtttcaaaat taccaacaga tgaaatcgta ggtggggttc
     6781 tcttaaatca gaaagtaaat cctcaaacgt tagccaaaga agaagataaa ttaaaactaa
     6841 ttgctttgtt acgaacattc tttaatcgtt tacatgggta ccatattcaa tacaatgttg
     6901 tttccagaga gacgttgatt gacgctcaga aacatcctga aaaacacaga gacttaattg
     6961 ttcgtgttgc aggatactct gcattcttca atgttctttc taaggcaacc caagatgaca
     7021 ttataggacg tactgagcat actttgtaaa ataaagaggt tctttttatg gaatttatgc
     7081 ttgacacatt aaatttagat gagattaaaa agtggtctga aattttgccg ctagctgggg
     7141 taacttcaaa tcccactatt gcaaaaagag agggttctat taattttttt gaacgaatca
     7201 aagatgtaag agaattgatt ggctccacac cctctattca tgttcaggtg atttctcaag
     7261 attttgaagg catcttaaag gatgctcatg aaattcgaag acaagcagga gatgatatat
     7321 ttatcaaagt acctgttact ccagctggat tacgtgcaat aaaggtgcta aaaaaagagg
     7381 gctaccatat cactgcaaca gctatttata cagttattca gggattatta gctatcgaag
     7441 caggagcgga ttacctagct ccatattata atagaatgga aaatctgaac attgattcaa
     7501 attctgtcat tcgtcaatta gttcttgcta ttgatagaca gaactctcct agtaagattt
     7561 tggctgcatc ctttaaaaat gtagcacaag taaataatgc tttagctgca ggtgcgcatg
     7621 ctgttacagc aggagcagat gtttttgaat cagctttcgc catgccatct atccaaaagg
     7681 cggttgatga tttttctgac gattggtttg ttactcaaaa tagtcgttcc atttagatag
     7741 agaggaaata catatgagaa tttttgctag tccttctaga tatattcagg gggaaaatgc
     7801 cttgtttgaa aatgccaaat caattttgga tttgggaaat taccctattc tattatgcga
     7861 tcagttggtt tatgatattg ttggaaaacg atttgaagat tatctacata ggtatggttt
     7921 ccatattgtt ctggcgctat ttaatggtga agcttctgac aatgaaatca atcgagttgt
     7981 tgccttggct gagaaagaaa attgtgatag tattatcggt cttggtgggg gaaagacgat
     8041 tgatagcgca aaagctattg cagatttgat tgaaaagcct gttattattg ctccaacaat
     8101 tgcatcgacc gacgcacctg tatctgcttt atctgttatt tatacagatg aaggtgcatt
     8161 tgatcattat ctattttatt ctaaaaatcc agatttagtt ttggttgata caaaagttat
     8221 ttcacaagcc cctaagcgtt tattagcgtc tggtattgca gatggtttag caacttgggt
     8281 tgaggcgcgt gcggttatgc aggcaaatgg aaaaactatg ttgggacaac agcaaacatt
     8341 ggctggagtt gcaattgcga agaaatgtga agaaacgctg tttgcagatg gtttacaggc
     8401 tatggcagct tgtgaagcta aagtggtgac accagcatta gaaaatattg ttgaagctaa
     8461 tactttattg agtggtctag gttttgaaag tggaggatta gctgcggcgc atgcaattca
     8521 taatggtttt actgcattga caggtgacat tcatcattta acacatggtg aaaaagtagc
     8581 ttatggaact ttagtacaac tattattgga aaatagacct aaagaagaac ttgataagta
     8641 tattgagttt tacaaaaaaa ttggtatgcc aacaactcta aaagaaatgc atttggatca
     8701 agttggatat gatgatttaa taaaagttgg taaacaagca actatggagg gtgagacaat
     8761 tcatcagatg ccgtttaaga tttcgccttc agatgttgct caagctatta tcgctgtaga
     8821 tgcctatgta aattcaaaat aaacaataag gactactgtt ttccaaatgg tagtctttta
     8881 ttgatccccg tattgaattc tatagaagat tgaaatagga tgagaa
//
LOCUS       DAVKBK010000069         8926 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVKBK010000069 DAVKBK010000000
VERSION     DAVKBK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.069"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            122..277
                     /locus_tag="VWX69_001767"
                     /pseudo
     CDS             122..277
                     /locus_tag="VWX69_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="VWX69_001768"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="VWX69_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU9193070.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="VWX69_001769"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="VWX69_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU9193071.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKANFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7614..8792
                     /locus_tag="VWX69_001770"
     CDS             7614..8792
                     /locus_tag="VWX69_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193072.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         2760 a         1866 c         1895 g         2405 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagaaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct accagtcgac attaagatac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      301 cttttttatt atgtgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cggacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagctaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 atcatgagat gaccaaatcc cagatgagtt ttttggactt ggagaattta acagatgagg
      901 ataagagggc ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaaggtc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1021 gtagtgattt taatcaaatc accttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgttga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcctgc tcaggactgt tctcaaactc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagtat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg attaatcttc ttagaactga tttgtatact gacctcagtc
     1681 agtctgatat tgatgctttt gagcaatata tccgctatct tggtatcaat ggcttgccag
     1741 cctttcagca aatcttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1861 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     1921 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     1981 aggctttctg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2041 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2101 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2161 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2221 gtcttctgac agatgaagaa aggcaaaacc taaaccaagc gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2341 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2401 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagga
     2461 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2521 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2581 aggttctgtc gcgtgtcata ggtaaaaaac tagatctgca aggtctggaa aatccagcta
     2641 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2701 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2761 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcgt cctgatgccc
     2821 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttacagttg cctaatgaag
     2881 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3001 cacggacgac tggacatatt ctccgacaca atccagccat cgaaaccatc aaagaagaag
     3061 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3121 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3181 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttaccaac ctatcttgct gccctaaaaa gagaagggaa gcagaacttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggctaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctag
     3661 aaaaattgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggt
     3721 ttgaaaaaat aagagaggag ttaaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3841 acaaatcgaa gctatctaca cttctggtca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg cagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgatctca aacaacactt
     4081 gggtcgccag ttggcagacc tacccaacgc tgccatcgga accatggact ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agagctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc ggcagcaagt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctctggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagttcg atagtcaggc
     4621 ttatcaggca gtacttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgtgctct
     4681 gactaatgcc agccgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagacccag tttactaaac taggacaatt atcagaccag atagcgattc tcgactatca
     4801 agaacgttat catggagaca cttggaaact agctaaaacc ttccaatctt tcatgagcga
     4861 ttttgtagag gcttatcgtc agagaaaacg acaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagagaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatccccaa gaaggcaagc tcattctcct caaggcaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac aagcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggcagaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg aattcctgtc aaaactgacg gagagcaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5641 tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttg gttttgatga
     5701 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5761 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga ttcacacagc
     5821 tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct tgtatgccaa
     5881 aacccactct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     5941 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6061 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6121 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6241 gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag aagaccacta
     6301 tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaagtca agcaataccc
     6481 agcagccaaa aatgggaaac taaatagcaa tactagactg caagcacgga atttccaaga
     6541 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacaagttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agtactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtataac ttatactctt tgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7501 ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgttttgag ctgattgcgg
     7561 ctagctttct agtttgctct ttgattttta ttgagtatta gaaaggagac ctcatgacac
     7621 ttccagttag aaaatccctg cacgatgcag ttttacaggc ttcgaaagcg gatacttggg
     7681 aacaagctac caaggaatgg aatgaagttt ccttgatttt taacggtatc ggccgtagca
     7741 attgtgtctg tggaaatgcc atcaaatacg cttatgaact ctttaacggt gtcacaggcc
     7801 aacgcctctt tccaattggt agcgactgtg ttcgtcattt tcatcgattg tcccttgacc
     7861 agcaattgga agaggaagaa aaactgctca gaaaggttga aaatctaacc agaaaagctc
     7921 agaaaaagga aaaaatcaag gtcaataaaa gtgactttga cgagcgactt ctaaaatggc
     7981 tctgggaaaa aggtgttttc aaacccaatc gtggcaatca atttgcgcct gagagagact
     8041 accagctttt cctagaagtc tttcagggag gaagttggac caaggcggaa ccaaagaaaa
     8101 aggctcggat ggaagaagtc cttgaaaagt gtatcaaacc ctttttactt gggaaatcgg
     8161 atgaccaact ctaccttgtc aagctaggca aggagaaaat tgactacgaa caagaactcc
     8221 gtatccaggc agagaaagaa cgcaagaaga gggataaaat cgccaagcaa tatgcagaca
     8281 atctggttct agccatggga cccgcagagc gtgcttatca agattacttt ggctttacag
     8341 agaccctgac tcaagaagaa cgcaagtggg aaaaaattct ttttggtaaa aatagagcag
     8401 aacgggctat caaggccaaa caataccaaa aagagctgga aaaagaccaa cgaattgcca
     8461 gtcaggatcc aattgaaaga aaacagaagc agacttggct cctcaattcc tattttcgtg
     8521 agcttcctga agaaaaagct cgattttcta ggctcttatt agaatatcga aaaagtggtg
     8581 aagtaccctt ttcaactgaa tacctgtccg atcatctcat cgactttttc tataaaatga
     8641 aagcctttga atttgaaatc gcaccagaac aagtccgaga ttttctaaaa aaaagcctgc
     8701 aggaagacca tcgctcatca gcacaaggaa gctggataga aggaattctc ctcaactgcc
     8761 tcaaaccatt tttagaacga ttagtgatat gagtaacacc taccgtgtaa atttcatggt
     8821 aggtgttatt gtacccccaa ataatataaa acaaagtatg aaagcgcatc tcaattttaa
     8881 gacttttttg taaattaaga gtataattaa ggtatactgc cttttc
//
LOCUS       DAVKBK010000070         8804 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVKBK010000070 DAVKBK010000000
VERSION     DAVKBK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8804
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.070"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..455)
                     /locus_tag="VWX69_001771"
     CDS             complement(<1..455)
                     /locus_tag="VWX69_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HEU9193073.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTG"
     gene            complement(442..1314)
                     /gene="hslO"
                     /locus_tag="VWX69_001772"
     CDS             complement(442..1314)
                     /gene="hslO"
                     /locus_tag="VWX69_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU9193074.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            1479..2906
                     /locus_tag="VWX69_001773"
     CDS             1479..2906
                     /locus_tag="VWX69_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9193075.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            3065..4573
                     /gene="glpK"
                     /locus_tag="VWX69_001774"
     CDS             3065..4573
                     /gene="glpK"
                     /locus_tag="VWX69_001774"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU9193076.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNFVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            4615..6441
                     /gene="glpO"
                     /locus_tag="VWX69_001775"
     CDS             4615..6441
                     /gene="glpO"
                     /locus_tag="VWX69_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU9193077.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            6511..7215
                     /locus_tag="VWX69_001776"
     CDS             6511..7215
                     /locus_tag="VWX69_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9193078.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            7512..7715
                     /locus_tag="VWX69_001777"
     CDS             7512..7715
                     /locus_tag="VWX69_001777"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193079.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(7802..8410)
                     /locus_tag="VWX69_001778"
     CDS             complement(7802..8410)
                     /locus_tag="VWX69_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193080.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         2558 a         1742 c         1983 g         2521 t
ORIGIN      
        1 cagccggtac gcattttgac agtaagtggg atatcaagga cagactggac cttgttgatg
       61 atagagtaga tcttgtcagg atccttgagc cacatagctc cagcttcgtt cttcacgatt
      121 ttgttgacag ggcagcccat gttgatatcg acgatatcgg tcttggtgtt ttcttggatg
      181 aattctgctg cgcgtgctag gctgtcttca tcgctaccaa aaagttggat agagacaggg
      241 ttttcgccct catcgatatg aagcatgtgc agggtttttt cgttgttgta ttggattccc
      301 ttgtcagaga ccatttccat tacaacgagt ccagctccga gctcttttgc gatggtacga
      361 aaggctgagt tggtcacgcc agccataggc gctaaaacgg tacgattggg aatctcaaca
      421 ttgccaatca taaaaggtgt attaagattt gtcacgaatg agttcctcca ggtccttttc
      481 atcaaagttg taagtagttt ggcagaattg acaagtgatt tctaccccgt ggtcttcctc
      541 tttcatttcc tgtaagtctg agcttggaag gctggcaaga gcgttcataa agcgttcatg
      601 gctacagtca cattggaaac ggatttcttc ttcagaaaga cgcttgtagg cttcgtcccc
      661 gtagatagcc ttgaggaggg cttcgatatg gtcgtcgctt tcgagaagag tagagatagc
      721 tggcatttct tggatgcgtt tttcaaagcg agcaatctct tctttcttgg ctcctggcaa
      781 gacttgaact aggaaaccac ctgcaacctt gaccttgtct tcctcgtcca aaaggacatt
      841 gaggccgacc gctgaaggcg tttgttggct ttcagtaagg taaaaggcaa ggtcttcacc
      901 gatttctcca gagatgaggg gagttataga gttgtaagga tttccagcac cgtagtctgt
      961 gataacgagg aattgaccat ttccaacaaa aggtccgact aggacttcac cagtcgcagt
     1021 ctttttgatg tcaacaccag gattttgaac atagcctttg acgttcccct tggtatcagc
     1081 gacggtgata atagcaccta gagagctaga gcccaacacc ttaactgtaa gtttggtatt
     1141 tcctttttca ttggctgcga gaatctggct ggcgataaga gttcgaccaa gcgctacagt
     1201 tgagctagct tgggtttgat gtttttcttg agcagtgcgg acggtttccg tgctatcaag
     1261 gacaaaagca cgaaaggctc cgctttctga tatagtttta ataattttat ccatagctac
     1321 tattttagca taaaaatgcc caaaggggga gccgtgtgtt tactgatttt caggataatg
     1381 gaccaggaaa tcagcatgaa aataaaaaga gaaacagatt attttagcat ttgtaagatt
     1441 tatgctatgc ttaaggtaga aaatgaaagg ggtaacaaat gtatttagga gatttgatgg
     1501 agaaagccga gtgtggtcaa ttttcaatcc tttcctttct attacaagag tctcagacga
     1561 ccgtcaaggc tgtaatggaa gaaacaggat tttcaaaagc aaccctaacc aaatatgtca
     1621 ccctgctcaa tgacaaggct ttggatagtg gcttagagct ggctattcac tcagaagatg
     1681 aaaatctgcg tctgtctatc ggtgcagcta ccaaggggag agatattcgg agcttgtttt
     1741 tggagagtgc tgttaaatac cagattttgg tttatcttct ctaccaccaa cagtttttag
     1801 cccatcagct ggctcaagaa ttggtgatta gcgaggctac gcttggtcgt cacttggctg
     1861 gtttaaatca gattttgtca gaatttgatt tatccatcca aaatggacgt tggcgaggtc
     1921 cagagcatca gattcgctat ttctatttct gtcttttccg aaaggtctgg tcgagtcagg
     1981 aatgggaagg tcacatgcag aaaccagaga gaaaacagga gattgccaat ttagaggaaa
     2041 tctgcggtgc aagtttgtct gtggggcaga aattggactt ggttctctgg gctcacatca
     2101 gtcaacaacg tcttcgggtc aatgcttgtc agtttcaagt catagaagag aaaatgcgag
     2161 ggtattttga caatattttc taccttcgtt tgctgagaaa ggttccgtcc ttttttgctg
     2221 ggcaacatat tccactagga gttgaggatg gtgagatgat gatattcttc tcttttctcc
     2281 tatctcatcg cattcttcct cttcatacta tggagtatat tcttggtttt ggagggcagt
     2341 tggcagattt actgacgcaa ttgattcaag aaatgaagaa ggaggaacta ttgggggatt
     2401 atacagagga ccatgtcacc tatgaactca gtcagctttg tgctcaagtc tatctctata
     2461 agggctatat tttacaggat cgctacaagt accagttaga gaatcgtcat ccatatttac
     2521 tgatggaaca tgattttaaa gagacagcag aggagatttt tcatgctcta cctgcttttc
     2581 aacaggggac agatttagat aagaagattc tctgggaatg gctccagtta atcgaatata
     2641 tggctgaaaa cggtggccag catatgcgga ttggtctgga tttgacatct ggttttcttg
     2701 tcttttcaag gatggcagcc attttgaaac ggtatttgga atacaatcgt tttattacca
     2761 ttgaagccta tgaccctagt cggcattatg atttgctggt taccaataac ccgattcata
     2821 agaaggaaca gacaccagtc tattatttaa aaaatgactt ggatatggag gatttggtag
     2881 cgattcgcca gttattattc acttaaaagg cttggttaat ccaggtcttt tttgtgaaat
     2941 tcacacaatc tcctcacatt tttttaaaaa ttaaaaaaag ttgataaaca agaaagcgct
     3001 ttattttgta tactagtaag tgtaaagagg aaacacctca agatctttat caggaggaca
     3061 gtacatgtca caagaaaaat acatcatggc cattgaccag ggaactacaa gttctcgtgc
     3121 catcattttc aacaaaaaag gggaaaaggt tagctcgagt caaaaagagt ttacccagat
     3181 tttccctcag gcaggttggg ttgagcacaa tgccaatgaa atttggaact ttgttcagtc
     3241 agttattgcg ggtgctttca tcgaaagtgg tgtcaagcca aatcaaatcg aggcaatcgg
     3301 gattaccaac caacgtgaaa caacggttgt ctgggataag aaaacaggac ttcctatcta
     3361 caatgctatc gtttggcagt cacgccagac agcacctttg gctgagcaac taaaaagcca
     3421 aggttatgtg gaaaaattcc atgaaaagac tggtttgatt attgatgctt acttctctgc
     3481 taccaaggtt cgttggattt tggatcatgt agaaggtgct caagagcgag cagaaaaagg
     3541 ggaattgctc tttggtacta tcgatacttg gttggtttgg aaattgactg acggtgcggc
     3601 tcacgtgact gactactcaa atgcagctcg taccatgctt tataacatta aagaactcaa
     3661 atgggatgat gagattttgg aaatccttaa cattccgaag gctatacttc cagaagttcg
     3721 ttctaactcc gaaatctacg gcaagacagc tccattccat ttctacggtg gagaggtgcc
     3781 aatctcaggt atggctgggg accaacaagc agccctcttt ggacagttgg cttttgagcc
     3841 aggtatggtt aagaatactt atggaacagg ctctttcatc atcatgaata ctggggaaga
     3901 gatgcagttg tctgaaaaca acctcttgac aaccattggt tacggaatca acggtaaggt
     3961 ttattatgcc ttggaaggtt ctatcttcat cgcaggaagt gctattcagt ggcttcgtga
     4021 cggtcttcgc atggttgaaa attcaccaga atctgaaaaa tacgctcgtg attctcacaa
     4081 caacgatgaa gtttatgtcg ttccagcctt tacaggtcta ggcgctccat actggaacca
     4141 aaatgctcgt ggttccgtct ttggtttgac tcgtggaaca agcaaagaag actttatcaa
     4201 ggcgactttg caatctattg cttatcaagt gcgtgatatc atcgacacca tgcaagtgga
     4261 tactcagacc gccattcaag tactgaaggt ggatggtggt gcagccatga acaacttcct
     4321 catgcagttc caggcggata ttttaggcat tgacattgca cgtgctaaaa acttggaaac
     4381 aacagctcta ggagcggcct tcctagcagg tttgtcagta gggtactgga aagacttgga
     4441 cgagttgaaa ctcttgaacg agacaggaga actctttgag ccatctatga acgaatctcg
     4501 caaggaacaa ctctacaagg gctggaagaa ggctgtgaaa gcaactcaag tctttgcgga
     4561 agtagacgac taatactggc agaataaagc gatttattta gaaagtgtgt aaatatggaa
     4621 ttttcaaaaa aaacacgtga attgtcaatt aaaaaaatgc aggaacgcac cctggacctc
     4681 ttgattatcg gtggaggaat cacaggagct ggtgtagcct tgcaggcggc agctagcggt
     4741 cttgagactg gtttgattga aatgcaagac tttgcagaag gaacatctag tcgttcaaca
     4801 aaattggttc acggaggtct tcgctacctc aaacaattcg acgtagaagt ggtctcagat
     4861 acggtttctg aacgtgcagt ggttcaacaa atcgctccac acattccaaa accagatcca
     4921 atgctcttac cagtttacga tgaagatgga gcaaccttta gcctcttccg tcttaaagta
     4981 gccatggact tgtacgacct cttggcaggt gttagcaaca caccaactgc gaacaaggtt
     5041 ttgagcaaga aagaagtctt ggaacgccag ccaaacttga agaaggaagg cttggtagga
     5101 ggtggagtgt atcttgactt ccgtaacaac gatgcgcgtc tcgtgattga aaacatcaaa
     5161 cgtgccaacc aagacggtgc cctcattgcc aaccacgtga aggcagaagg cttcctcttt
     5221 gacgaaagtg gcaagattac aggtgttgta gctcgtgatc tcttgacaga tcaagtattt
     5281 gaaatcaagg cccgtctggt tattaataca acaggtcctt ggagtgataa agtacgtaat
     5341 ttgtctaata agggaacgca attctcacaa atgcgcccaa ctaagggagt tcacttggta
     5401 gtggattcaa gcaaaatcaa ggtttcacag ccagtttact tcgacacagg tttgggtgac
     5461 ggtcgtatgg tctttgttct cccacgtgaa aacaagactt actttggtac aactgataca
     5521 gactacacag gtgatttgga gcatccaaaa gtaactcaag aagatgtaga ttatctactt
     5581 ggcattgtca acaaccgctt tccagaatcc aacatcacca ttgatgatat cgaaagcagc
     5641 tgggcaggtc ttcgtccatt gattgcaggg aacagtgcct ctgactataa tggtggaaat
     5701 aacggtacca tcagtgatga aagctttgac aacttgattg cgactgttga atcttatctc
     5761 tccaaagaaa aaacacgtga agatgttgag tctgctgtca gcaagcttga aagtagcaca
     5821 tctgagaaat atttggatcc atctgcagtt tctcgtgggt ctagcttgga ccgtgatgac
     5881 aatggtcttt tgactcttgc tggcggtaaa atcacagact accgtaagat ggctgaagga
     5941 gctatggagc gcgtggttga catcctcaaa gcagaatttg accgtagctt taaattgatc
     6001 aattctaaaa cttaccctgt ttcaggtgga gaattgaacc cagcaaatgt ggattcagaa
     6061 atcgaagcct ttgcgcaact tggagtatca cgtggtttgg atagcaagga agctcactat
     6121 ctggcaaatc tttacggttc aaatgcaccg aaggtctttg cacttgctca cagcttggaa
     6181 caagcgccag gactcagctt ggcagatacc ttgtcccttc actatgcaat gcgcaacgag
     6241 ttggctctta gcccagttga cttccttctt cgtcgtacca accatatgct ctttatgcgt
     6301 gatagcttgg atagcatcgt tgagccagtt ttggatgaaa tgggacgatt ctatgactgg
     6361 acagaagaag aaaaagcaac ttaccgtgct gatgtcgaag cagctctcgc taacaacgat
     6421 ttagcagaat taaaaaatta agaaaaaata aaagaggtgg agggcagcat tccttgtcgc
     6481 ccgtcccttc tttttaatgg agacagaaag atgatgaatg aattatttgg agaatttcta
     6541 gggactttaa tcctgattct tctaggaaat ggtgttgttg caggtgtggt tcttcctaaa
     6601 accaagagca atagctcagg ttggattgtg attactatgg gttgggggat tgcagttgcg
     6661 gttgcagtct ttgtatctgg caagctcagt ccagctcatt taaatccagc tgtgacagtt
     6721 ggtgtagctt taaaaggtga cttgccttgg gcttccgttt tgccttatat cttagcccag
     6781 ttcgcagggg ccatgttggg tcagattttg gtttggttgc aattcaaacc tcactatgag
     6841 gcagaagaaa atgcaggcaa tatcctggca accttcagta ctggaccagc catcaaggat
     6901 actgtatcaa acttgattag cgaaatcctt ggaacctttg ttttggtgtt gacaatcttt
     6961 gctttgggtc tttacgattt tcaggcaggt atcggaacct ttgcagtggg aactttgatt
     7021 gtcggtatcg gtctatcact aggtgggaca acaggttatg ccttgaaccc agctcgtgac
     7081 cttggacctc gtatcatgca cagcatcttg ccaattccaa acaagggaga cggagactgg
     7141 tcttacgctt ggattcctgt tgtaggccct gttatcggag cagccttggc agtgcttgta
     7201 ttctcacttt tctagtttat actcttcgaa aatcaaattc aaaccacgtc agcgtcgcct
     7261 taccgtactc aagtacagct tgcggctagc ttcctagttt gctctttgat tttcattgag
     7321 tattagaaaa caattatgtt gatagagctt gggcaagagc ccaatttcag caaaaaatga
     7381 agtaaatctt ctcataataa aacgcatcat atcaagcacg aaaattccac gaggtcaact
     7441 acagtcagaa agctgaacaa caagccaaaa cgcccaaaaa aggcggcaaa aagcaagcac
     7501 ctgcaagcaa cgtgccgaaa tggtcaaatc ctgattatgt caacgaatta gacccaaaaa
     7561 tcgttgatat gctagtagaa tttcacaagt cacaaggcac tttggaaact cccgaggcgc
     7621 aagcagaaat cgcccaaaaa cgtgaagaaa tcgagcaaag gagagctgag cttgaggata
     7681 aaaaacaaga gcttttgaac cgcttgaaca aatagagttt cgcaagtatt atgcttacaa
     7741 attacttgag caattaacta aaatataaac cctgcctaga tataaaggca gggtttatat
     7801 tttagaaatt cacgtaggtt gttacggttt ttacataccc agtatagttt gagtttctat
     7861 agtattcagt gataaacttc cattttcttt gagcaacatg gatataagta cttgttatgt
     7921 agtatggata tgggctttgt gaatccaagt aagactgata agcttgtata ccaaaatatg
     7981 ctccaccaat tattgcaccc catggacccc ccaataaagc acctatccta ccaatcatat
     8041 aactgattcc agcaccagtc atgaagttag cgaatgtgtt agcttgttta ttcccatgta
     8101 ttgtgttgac gtaattccaa acattaggat cgtatgatct aaaagatata tttaggtcga
     8161 tttcattctt ttgataagcc atataaaatg ccccattgat atagacgccg tcagcacgtc
     8221 gttcaatagt gtctacactt ccatctggat tgacaacctc aagaacttca tcgcttaaaa
     8281 tatttacttg cgtatctccg aaccgcactg atgagccatt ctcaaactga gcctcaccag
     8341 atacaacttt agagtttgcc gataagctat catcagcaaa aacaacaagc gacggggaaa
     8401 tgctagacat acagaaaaca gacataacta gcaaacacat gcatttaaac atcttagaca
     8461 taacggaaac tcttttgtat ttttgatttt tttcaacttt tattatacaa taaaaccaaa
     8521 taaaaagaaa gcggtaacaa tatgcttaat gcgaaaattt tttatatatt tttatgtttg
     8581 atcgttatcg aaactacagg cttgttgttg ttgaaaagag gtctcgaaat gggttattta
     8641 gacacagaag ctattatcct cgcagttttt tcatttgctt tttacaacct atgttcattc
     8701 gcttgggtct gctctacaat aaaaaataaa tagacgtatt ttcaaaaaaa aaaaaatgaa
     8761 tatttatatt agcaaaatga cgatttaaat cgtcgttttt ttgt
//
LOCUS       DAVKBK010000071         8797 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVKBK010000071 DAVKBK010000000
VERSION     DAVKBK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8797
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.071"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(1..401)
                     /locus_tag="VWX69_001779"
                     /pseudo
     CDS             complement(1..401)
                     /locus_tag="VWX69_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(418..1221)
                     /locus_tag="VWX69_001780"
                     /pseudo
     CDS             complement(418..1221)
                     /locus_tag="VWX69_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(1314..1472)
                     /locus_tag="VWX69_001781"
     CDS             complement(1314..1472)
                     /locus_tag="VWX69_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU9193081.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(1543..1972)
                     /locus_tag="VWX69_001782"
                     /pseudo
     CDS             complement(1543..1972)
                     /locus_tag="VWX69_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2067..2507)
                     /locus_tag="VWX69_001783"
     CDS             complement(2067..2507)
                     /locus_tag="VWX69_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9193082.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKASQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILRQ"
     gene            2498..2806
                     /locus_tag="VWX69_001784"
                     /pseudo
     CDS             2498..2806
                     /locus_tag="VWX69_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2961..3284)
                     /gene="tnpB"
                     /locus_tag="VWX69_001785"
     CDS             complement(2961..3284)
                     /gene="tnpB"
                     /locus_tag="VWX69_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9193083.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(3265..3450)
                     /locus_tag="VWX69_001786"
     CDS             complement(3265..3450)
                     /locus_tag="VWX69_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193084.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(3723..4334)
                     /locus_tag="VWX69_001787"
     CDS             complement(3723..4334)
                     /locus_tag="VWX69_001787"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEU9193085.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            complement(4357..5742)
                     /locus_tag="VWX69_001788"
     CDS             complement(4357..5742)
                     /locus_tag="VWX69_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEU9193086.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            complement(5743..7518)
                     /locus_tag="VWX69_001789"
     CDS             complement(5743..7518)
                     /locus_tag="VWX69_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEU9193087.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            complement(7581..7901)
                     /locus_tag="VWX69_001790"
     CDS             complement(7581..7901)
                     /locus_tag="VWX69_001790"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEU9193088.1"
                     /translation="MEANKYKIGIIGSHDIILPFSMIGFDIFSAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            complement(7891..8787)
                     /locus_tag="VWX69_001791"
     CDS             complement(7891..8787)
                     /locus_tag="VWX69_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEU9193089.1"
                     /translation="MAFILEATPYHLSIDVLENPSQTEISLMTKLVNDYRWAYAESPS
                     DKIVTLFALRYVYHNIKVLLKSKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLP
                     DFMVHEVESIWNEYETFNNIRVLDVGADLAYFKHLKLLSNELGEVLSQVIVAMIDFYN
                     IITVKRGLSQNKSHGDILQLLSDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFST
                     YELKMQDATISSSELEFLCDLLLYKTLDQGRYNVDGPLVLARYLLGCEFEVKNLRMII
                     SALQNTIPFESIKERIRPHYGS"
BASE COUNT         2758 a         1802 c         1377 g         2860 t
ORIGIN      
        1 gttattcttt cctcattaat agtgtctaat gcactagttg cttcatctaa aattacaata
       61 ctaggattat ttattaatgc acgtgccagt gctatccgtt gcctttgccc acctgaaata
      121 tttgacccca tctctgagat gatagtatta aatttcatcg gcatagccat gatttcatca
      181 tagatttgaa ctgctttaca aacttcctct atcttttgtg aagtaacttc gtgctttaaa
      241 gttatattat caagaatact tcggttcaat aaaaatgaat cctgtggaac tactcctaaa
      301 ttttgactta atattttttt atctatttga ttaatattta caccatcaaa taaaactttt
      361 cctgtatcaa tcttatataa tcttgatggt atttttgata atagacttcc tgcaaaacta
      421 gaatcctagt tcatgattga taataccagc aatcaaattc attcgtaatc cgaagcgttt
      481 agatgatttc gataggttgt tgaaatcatt ttaaacgttt ttactttggc aaagatgttc
      541 tcaaccttgc ttctctcctt agatagcgca tggttataga ctttatcttc aattgttagc
      601 ggtttgagtt tgctggattt acgtgaagtt tgtgcttgag gatatatctt catgagccct
      661 tgataaccac tgtcagccaa gattttacca gcttgtctga tatttctgcg actcattttg
      721 aacaacttca tatcatgaca atagttcaca gtgatatcca aagaaacaat tctcccttga
      781 cttgtgacaa tcgcttgagc cttcatagcg tgaaatttct ttttaccaga ataattcgct
      841 aattcttttt ttagggcgat tgatttttac ttccgtcgca tcaatcatta ccgtgtcctc
      901 agaactgaga ggagttcttg aaatcgtaac accactttga acaagagtta cttcaaccca
      961 ttggctccga cggattaagt tgctttcgtg aataccaaaa acagccgcaa tttgttcata
     1021 agttcgatat tctcgcacat attgaagagt ggccataaga aggtcttcta gacttaattt
     1081 aggttttcgt ccaccttttg cgtgtttaag ttgataagct gtttttaata cagctaacat
     1141 ctcttcaaaa gtcgtgcgtt gaacaccaac aagacgctta aatcgtgcat cggttagttg
     1201 tttacttgct tcatcattca tagaactact ataccatatt ttgtttcgca ggaagtctat
     1261 tgaaaaatct ccagactgga gaactcacgg atagttccta atctggagat ttcttatttg
     1321 cacttttctt gtacaacttt agtccatggt aaataagcct ctaaaacctc tttgtttacg
     1381 agagtttcct cgtttggaag acattctaga agataggata gatatttctc gctatttaat
     1441 tgatgacgtt tagctgtttc caacaaactc ataataatag ctcttgcttt agctccttca
     1501 aaactttgag aaaataacca ccctcgcttt tttaaactga gcttaggcta aaagagtcca
     1561 ctggactctt ttactccgtc ccataaccaa tgatttaatg gcgcgttcag ctagattatt
     1621 ggaaaggacc agatgtccgt ctttcaaaat ggtcttaaag gtttcttcat acttgaggct
     1681 gtattcaatt gcccttccta gttttgaacc tgctaaaact gactgacgcc ggcactaagc
     1741 aaagaagtct tccattaagg gctggagatg ttcttgacgt ttctgtagtc gttcatcagc
     1801 tggcaaagcc tcccagtttc tttccaagga aaataactga tcacaataag ctaaaccttt
     1861 agctcctaag gatgatttat ccgcttgctt gggggggcgc ttcaaaaaac ttccttctca
     1921 catgcgccca acatccaaca agttcagctt cttccagttg acgataagca gacgagcggt
     1981 tcgaagttta ccaagcttag cgtcgccttg ctcctaaacc ttggactgct atcgcatagg
     2041 cagaactaga ggactaaagt cctaagttac tgccgcaaaa tatcacaatg cacatagcca
     2101 gaataatctc ctaggaattc ttgtactact gaaccacttc gacactgatc atggtggtaa
     2161 agcgtaatcc cttgtttctc tgctttacct gacaaaaaag tccaatagta agtcagctga
     2221 ctatcactct ctagcaccct ataagaagtt tcatccgcat gaagtaaggg ctgagtcaat
     2281 agtctctctc gcaagaggtt ataaaggggc tccaaatagt attgactcgc cttgatatgc
     2341 caattagaga tttccttacg tgtgattggt aaacccatcc tagcccaatc ttcttcttgg
     2401 cgataattgg gtaccttcag attaaacttc tgatggatgg tgtgagcgat aatagaagct
     2461 gagccaaagt tatgcgctaa aggggcttta ggaataggag atttcacaag cttatccaga
     2521 tgattatctt ttactcgtta tggacaatgc tatatggcat aaatcaagta ccttaaagat
     2581 tccgactaat attggctttg catttattcc tccatacaca ccagagatga accccattga
     2641 acaagtgtgg aaagagattc gtaaacgtgg atttaagaat aaagcctttt aaactttgga
     2701 agatgtcatg aatcaactcc aagatgttat acaaggactg gagaaggagg tgataaagtc
     2761 catcgttaat cggagatgga ctagaatgct ttttgaaagc agatgagtat aaaaagaaag
     2821 tcctcatttc aatagaaatc acgactttct gatggattta tagtaaaatg aaataagaac
     2881 aggacaaatc gatcaggaca gtaaaatcga tttctaacaa tgttttagaa gcagaggtgt
     2941 actattctag tttcaatcta ctatattttt ggagtgatag aaaagccctt cataagccag
     3001 tctacttgtt ctggtgtgag agctttgaca tccttttctg tacttagcca aatcaatctg
     3061 ccgttctcaa agcgtttata tagtagccaa aatccttgac catcccagta aaggacttta
     3121 aagcggtctt tacgtccacc acaaaagaga aagacttgac cggagaaagg atccaattca
     3181 aagtgggttt taaccagata agccagtgaa tcgattcctt gtctcatatc agttttccca
     3241 cacacgagat agacctcccc taggctagat agatgaattg tcatagagca acaccttatc
     3301 caaaagctgt tctaccattt cgagattgag agattgaaaa aaacttactt caagcttgcc
     3361 aatacgaatt ttaagcagaa tatcatttct ctttttagaa tcaaaacgac gagattgtgg
     3421 aatctctaca ggaacaatag gttgtggcat taaaatatcc tccaatagtt ttactttact
     3481 aatagtatac aggaggagct ccatgaatga tagatacctt gttatgacgc gcttactttc
     3541 tatataatta catttacgat ttactaatcc taaatctaga ttagtagaaa cattttcatt
     3601 atctaacaaa ccaaaatttt gaaaaagata tcctgatact gtcaataaaa aaagcttaga
     3661 aaggcttaaa gccttatcca agctgatatt tgttcatcta attaataatc taaataaagg
     3721 atctacttca ctttcataat acgaactaaa ttggctcttt ctgcctcctc tagtttcaat
     3781 tctatataat gaatagtttc cgacaagttt ggaataatcg agtattctaa accatttaca
     3841 cgtctacgtg ttttttctat ttcatcagcc attaactgac acgttttttc aacttctgcc
     3901 agtcttagta atttataaat taaactattc attgtagcaa atacatcatc catttcacta
     3961 ttagaagata aatagctgta ttcactgttc tcattttgag aagtaatatt catatgcatt
     4021 ctaggaactg ttacactcat gatattttct ttctcaacaa ataattcaat ttctttcgat
     4081 ggaattgaaa ataattcctc caccatttga gaattcttta atgatttagc aactgcaaag
     4141 gattttagat tatcaattag ataactttcc acttctttcc gaagttgatt attctcacga
     4201 atcaaagaaa taaatcgcct catcaattca tctcttttat cctttaataa cttatgtcca
     4261 cgttcagctg ttgtcaaacg ttcctttaag ttattcaatt ccatacgagt tggttttaca
     4321 ttcaaacgta ccatagataa tcactccatt tccggattaa acttctacca aaggtaagta
     4381 tttatcaagc aaatcatctt tgatacgttt taactctgtt ctaggaagaa ttgatagtaa
     4441 ttcccaccca agattcaacg tatcttctat atttcgattt ttataaaatc cttggtttat
     4501 gtactcttct tcaaaacgct ttgtaaacct cacatacaat ttatctacat cagataaagc
     4561 cgattctcct aatactactg ctaactcttc aacctttttc ccttgggcat aggctgcaaa
     4621 cagttgattc atagttggag catgatctcc acgagtttta ccttctccag atcccttatc
     4681 ttttaatcga gagagagaag gtaaaacatt gattggtgga cgataacctt gattatacaa
     4741 ctcatgcgac aaaataattt gcccttcagt aatgtatcca gttaaatcag gaattggatg
     4801 tgttatgtca tcttctggca ttgttaaaat aggaatctgt gtcaccgaac cttttttacc
     4861 aactaagcga ccagcccttt cgtatagagt tgataaattt gtatataaat atcccggata
     4921 gcctcgtctc cctggaactt cacggcgagc tgccgagact tcacgtaacg cttcacaata
     4981 gttagtcata tccgtcatga taactagaac gtgcatatct ttttcaaaag ctagatactc
     5041 tgccgcagtt aaagcaatgc ggggagttgc aatacgctca attgcaggat catttgccaa
     5101 gttcataaat aaaaccgaac gatcgatcgc tcctgttttt ctgagttctt ccataaaaaa
     5161 ctcagcttct tcaaaagtaa tacccattgc tgcaaataca accgcaaaat tttcatcaga
     5221 atttaaaaca gtcgcttgtc ttgctatctg agcagctaat tcattatgag gtaagcccga
     5281 acctgaaaat actggtaatt tttgaccacg tacaagagta ttcaaatgat caatagagga
     5341 gatccctgtc tgaataaatt catctggata atctctagat acaggattaa tagcttgacc
     5401 atcaatatct aaatatttct ctggaattaa atctggtcca ccatcaattg gttttcccat
     5461 cccattaaaa atacgaccaa ccatatcctc agatacagcc aattctaatg catgaccagc
     5521 aaaacgaatt ttagactttt ctaaatttat tccactagat ccttcaaaaa gctgaaccat
     5581 tgctttatct tcgtggatct ctaaaacttg tccacgacga atttctccat tatgaagttg
     5641 aatttcaact aactcattgt aagacacatt atttacttgt tcaacaatca taagaggccc
     5701 aacaacttca ctagcagttc tgtattcttt tataacactc atttatagac ctcctgtttc
     5761 taatatcaaa tgaatttgat gtgtaatctc atttgatata attttgattt catctaatct
     5821 atcttctgaa acatatttac ttctcgccat acggtctcga actgccacgg taccttccat
     5881 aatctctgta aagtaagaac ccaactctaa agcatgattt gcctgatcag caaaagtgag
     5941 aatattactt agcattgctt cttgttttgc aaacgaagtg aatgtatcta ccgaatcaaa
     6001 agcgttctgt tgcaaataat cttctcgaat ttgtttagca atttccatcg ttagtcgttc
     6061 attatcagac agagaatcaa ttccaacaag acgaacaatt tcctctaaac tagattcccg
     6121 ttgtaagtag ttcatcgcac gagttatttt actattccaa tctgtcttct ctttaccatc
     6181 tatataagtg cccacactgt ctttatatag tgaataagat gtaagccagt taattgcagg
     6241 aaaatgacgt cgctgtgcca acggagcatc aagcccccaa aaaactttca caatccgtaa
     6301 agtgttttga gtaactggtt ctgaaatatc tccaccaggt ggcgatacag ctccaatagc
     6361 agtaatcgtt ccttcacgtt ctggaagccc tagaacctga gaacgtcctg ctctttcata
     6421 atattcagcg atacgacttc ccagataagc aggataaccc tcatcaccag gcatttcttc
     6481 tagacgtcct gacatttcac gtagcgcttc tgcccaacgt gaagttgaat cagccataat
     6541 ggcgacagag tagcccatat cacgaaaata ctcagccatg gtaattcctg tataaattga
     6601 agcctcacga gcagcaacag gcatatttga agtattagca atcagaactg tccgttgcat
     6661 aattgattgt ccggtattag ggtcaatcaa ctcaggaaac tcattcagta catccgtcat
     6721 ttcatttcca cgttctccac aaccgacata aataacaata tcaacattgg caaatttagc
     6781 tacttggtgt tgtacaactg tctttcctgc tccaaacggt ccaggaactg ctgcagctcc
     6841 ccctttggtt actggaaaga atgcatcaat aactcgttga cctgtgatta atggttcttc
     6901 tggaattaaa cgtttagaaa caggacgcgc cttgcggaca ggccattttt gcataagcgt
     6961 tcctttatag aaactaccgt ccaatttttt tatttcatat acaacttcat caattgtaaa
     7021 atcgccagat gcaatagaaa cgacttctcc agatactcca taaggaacca taattttatg
     7081 attaactacc tcggtttcct tgacagttcc aagaatatca cccgtactca ctttttgacc
     7141 aattgctata gtggaatcaa aatgccactt aatatctcta tccaaacttg gaacttctac
     7201 cccacgaact agaaaatcat tatgagtagc caatttaaat cgatctaatg ggcgttgtat
     7261 gccatcaaac atttgagaaa tcaatcctgg ccctaattca accgagagag gttctccagt
     7321 tgtaacaaca ggttctcccg gaccaagacc agatgtttct tcatagactt ggatagatgc
     7381 ctgatctctt ctcatttcaa taatttcacc gattaaccct agcttaccta cacggcaaat
     7441 atcttgaata ttagcctcct gcatacctga tgcaataact agaggtcccg atacttttat
     7501 aatcttccct tgagtcaaag ttattctcct tactaagtcc aaaaattata gaataatatt
     7561 acagacaatt ttgtacatta ttataaaata ttgtgtccta ctgctttctc tacattatcc
     7621 tctatacgtt ttaatcctaa atttaaacct tgtttatgag tcggtaataa aataatagca
     7681 ggcacaactt gagaatcata atggcgaatt gtatctaata tcattgaagc aatgtcttca
     7741 gtgatataaa tgacaccata atcagattga gctaattttc ttagagtatt tatagcttct
     7801 tgttcttgat aggcagaaaa tatatcaaac ccaatcatgc taaagggtaa aataatatca
     7861 tggctaccaa ttatgccaat tttatactta ttagcttcca taatgcgggc gtatcctttc
     7921 ttttattgat tcaaaaggaa ttgtattttg aagagctgat atgatcattc taagattctt
     7981 tacttcaaac tcacatccca ataaatatct agcaagaact aacggcccat ctacattata
     8041 ccttccttga tctaaagttt tatacaatag taaatcacat aaaaattcta actcagaaga
     8101 tgaaattgtt gcgtcctgca tcttcaattc gtaagttgaa aagattgaat ctaagcttgg
     8161 atttatttta ttgaaccaca caaatatttc ttgattttct acaatgtata taaattcttt
     8221 agcagaaata cttccttcat ctgaaagtaa ttgtaaaata tccccatgac tcttattttg
     8281 agataaacca cgttttacag taataatatt ataaaagtca atcattgcaa caataacctg
     8341 agacagcacc tcacctaact cattagataa aagtttcaga tgtttaaaat atgctagatc
     8401 agctccgaca tcaagtacac gaatattatt aaaagtttca tactcattcc aaattgattc
     8461 tacttcatga accataaaat caggaagtgt atctgaatgt aaggaagaaa ctaaatgttt
     8521 taaactttct atatcaaaaa tccctattgg aattaataat ttagaaaaat ctttcttaat
     8581 tgccgcctta gattttaata aaactttgat attatgataa acatatcgta aagcaaataa
     8641 agtcacaatt ttatcagacg gactttcagc ataggcccat ctataatcat tgactaattt
     8701 tgtcattagc gaaatctctg tctgactagg attttctaaa acgtcaatcg ataaatgata
     8761 gggagttgct tctaagataa atgccaatgt ctccgta
//
LOCUS       DAVKBK010000072         8660 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVKBK010000072 DAVKBK010000000
VERSION     DAVKBK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.072"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            10..1011
                     /locus_tag="VWX69_001792"
     CDS             10..1011
                     /locus_tag="VWX69_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9193090.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    1223..1452
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1618..1695
                     /locus_tag="VWX69_001793"
                     /pseudo
     CDS             1618..1695
                     /locus_tag="VWX69_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2242..3603
                     /gene="trpE"
                     /locus_tag="VWX69_001794"
     CDS             2242..3603
                     /gene="trpE"
                     /locus_tag="VWX69_001794"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU9193091.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNSFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGVTDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3600..4166
                     /locus_tag="VWX69_001795"
     CDS             3600..4166
                     /locus_tag="VWX69_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU9193092.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            4177..5181
                     /gene="trpD"
                     /locus_tag="VWX69_001796"
     CDS             4177..5181
                     /gene="trpD"
                     /locus_tag="VWX69_001796"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU9193093.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDVRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5178..5945
                     /gene="trpC"
                     /locus_tag="VWX69_001797"
     CDS             5178..5945
                     /gene="trpC"
                     /locus_tag="VWX69_001797"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU9193094.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLNYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            5932..6531
                     /locus_tag="VWX69_001798"
     CDS             5932..6531
                     /locus_tag="VWX69_001798"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU9193095.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVVADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            6509..7732
                     /gene="trpB"
                     /locus_tag="VWX69_001799"
     CDS             6509..7732
                     /gene="trpB"
                     /locus_tag="VWX69_001799"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU9193096.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7725..8501
                     /locus_tag="VWX69_001800"
     CDS             7725..8501
                     /locus_tag="VWX69_001800"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU9193097.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(8473..8574)
                     /locus_tag="VWX69_001801"
                     /pseudo
     CDS             complement(8473..8574)
                     /locus_tag="VWX69_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
BASE COUNT         2575 a         1612 c         2076 g         2397 t
ORIGIN      
        1 aggactgaaa tgaaaaatat aaatgggaaa aaggtaacta tttatgatat tgcacgttta
       61 tcaggttttt ctccaaaaac agtttcacga gttattaatg gtggagtaaa tgttaaagaa
      121 gaaacttatc aagcgattca aaaagttata gaggaattgt cgtatattcc aaatgcgtat
      181 gcaaaaaatt taactaaaaa agaagctata aatatattga tttctgtaaa aaaaatcgac
      241 tcttttcctt taatttggtt tcatacgctg ttagataaag tgttacggac gtgtaaagaa
      301 tttggtgtta atgctatagt tgagtacttt ggagaggagg atacaattag taattcaatt
      361 atatcaagca caggtagcct agtagatggt gttattgttt tttatgaaag tgtagatgat
      421 atcagaattc agtatttaaa gaagaaccat atgccttttc ttgttttcgg tgaatctcaa
      481 acgtctggag tagtctatgt atctaataat aattttcaag ctacttatga tatgatgaaa
      541 gctgtaactg aagaaaaatt taaaaatatg tggttgctta tgggaggaga atcccatgtt
      601 aataaggatc gtgaaagagg tgtgcgttct tttctgaatg ataaaaatta ctttatggat
      661 ttaaaagtca tttatggctt atctacaatt gattcagttt attcttatgc aatgcagcac
      721 ttgactaccc aaaattatcc ggacattatt tttgtttcag gagatgaaaa ggttcagggc
      781 ttgattcgtg cgtgctatga gaaaggaatt cttattccag atgatatttc tatcattgga
      841 tttgataata ttcctatttc tcagtattat actccagctt tgtctacaat tgctcccaat
      901 tatgttaaat tggctaaaga aatgatagaa ggtgttttag caattattaa aggggaaagt
      961 gtcacatctg ttgaagtttc tcctaaattt gttaggagac agagtttcta gtattgttta
     1021 attcttgaaa atcctagtgg aaaagatgga gtgttctaaa ataagttctg tttagcctcc
     1081 attcagtttc tattgagttg gatccaattt ctaacaagtg ggacatgttc atgttcgatc
     1141 taaggaagac atggtcacat tcgaatgata ttttcaaaaa aatcgtaaaa aagtcttgac
     1201 aaagaaaaaa caaagtatta aaataagttc aacaaatcag aaaagtaact atttttgatc
     1261 ttcagggagc ctgtggtggt tgtgaatagg tggttggaag tagtgaaagt gggctgattt
     1321 tgaaaatgaa tttgaaacaa tgaaaattcg gtgcgcacac cttacagtgc agcttgttgt
     1381 taaacaaggc agagatgtaa agggatagtc cctttataat tgaggtggca ccgcgttacc
     1441 aacgccctca cacggaagta tattttgtgt gtgggctttt ttctatccgt cgtttggttt
     1501 atcttttatt agggccttaa gtcgctttga tgaacttgag ttctatctac agctccttgc
     1561 ctactactaa aagcaaacaa aaagctggac taatacgaaa aaagctagta atactcaatg
     1621 aaaatcaaag agcaaactag gaaactagcc gcaggttgct caaaacactg ttttgaggtt
     1681 gtggatagaa ctgacgaagt cagctcaaaa tactgttttg aggttgtgga tagaactgac
     1741 gaagtcagct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaaccat
     1801 acctacggca aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaggtgta
     1861 tcgaaataaa aatctcctca tcaatatctc tggtcgtgga ggcaaggacc tagctgcgat
     1921 tgcagattac ctagaagcta aaaaataata gatggaaaaa ttacagtctt ttctctcaca
     1981 gagagcttgt ggttgctgaa aacaagcaga gaaagctgta aagttgggtt catctgaaac
     2041 gagagaagaa aacatcattc tcaagggagt gccctttatc gcacagcctg ttacaggagg
     2101 tatctgagac aggaatgaga gataggagaa atcctataat tgaggtggca ccgcgaattt
     2161 cgtcctcacg caagttattt tgcgtgggga tttttcatac agtcaccacg gactagaagt
     2221 agaactgaaa gggaaattac aatggaacga atcattcatg gagatgtctt atcaccaatc
     2281 ttggcttata tgcgcttaaa ggggcaacac aaggttatct tagagagtat tccgagagac
     2341 aaggaaacag ctcgtttttc tatcttagcc tataatcctg tttttgagat taagtttgaa
     2401 aatggagttc tttatcaaaa tggtcaagtg attgatcgag atcccttgga tttcctttat
     2461 gaagtgattc ataagagtca gcaccactca gagctacctt ttggtggtgg agccattggt
     2521 tttgtgggtt acgatatgat ttcgctttat gaagaaattg gtcaaatccc tgaggataca
     2581 attgggacgc cagacatgca tttctttgtc tatgagagct atatggtctt tgaccacaag
     2641 aaggagaaga tacatgtcat agaggatgct ctctatagtg agcgcagtca agaggccttg
     2701 gaaaaatcct tgaaccaagt gcttgaggaa ttacgcattc ctgctccaaa tgaatttgaa
     2761 gacttggatt tatcaccact tgacttcaaa ccgcatatcg ctccacataa gtttgaggta
     2821 atggtagaaa cagctcgtga cttgattcgt aatggtgata tgttccaatg tgtactcagc
     2881 cagcgtttct cagcagaagt tactggaaat tcatttgact tctacagaaa tctccgcgtg
     2941 accaatccat ccaattacct ctatttctat gattttgggg attatcaaat catcggagct
     3001 agtccagaaa gtttagtttc tgtcaaaaat ggcatcgtga caaccaatcc gattgcaggg
     3061 acgcgaccaa gaggggttac ggatgaagaa gacaagacct tggcgactga cctcctctct
     3121 gatgagaagg aaacagcaga acatcgaatg ttggtagact tggggcgtaa cgatattggc
     3181 cgcatctctg aaacggccag tgtccaagtt actaagtata tgaaggtgga gctcttccgc
     3241 tacgtcatgc atttgaccag cgtggtcaag gggcgtttgc ttgcagaact cactgccatg
     3301 gatgccttga aagcaacgct tcctgctgga accgtttctg gagcaccaaa gattcgggcg
     3361 atgagacgca tctatgaact ggaaacggaa aaacggggcg tatatgcagg agcaatcggc
     3421 tacttgtctg cgacgggtga tatggatttg gccattgcca tccgaaccat gattctcaaa
     3481 aatcaaagag cctatgtgca ggctggggca gggattgtct acgactctat cgcccaaaac
     3541 gaataccaag aaaccattaa caaagcaaaa tctatgacta gaattggaga actaagacca
     3601 tgattttatt gattgacaac tatgattctt ttacctataa cttggcccaa tacattggga
     3661 attttgcaga agttcaggtt ctgagaaatg atgattccaa gctgtatgaa gaagctgaaa
     3721 aagcagatgg tctggtcttt tctcctggtc ctggttggcc agttgatgct ggaaagatgg
     3781 aagacatgat tcgtgatttt gcaggcaaga agccgattct agggatttgt ttgggccacc
     3841 aagccattgc agaagtcttt ggtggtaagc taggtttggc tccaaaagtc atgcatggga
     3901 aacagagcaa tatcaacttt gaagcgccat ctgttttgta tcaaggtatt gaggatggac
     3961 gtgcggtcat gcgttatcac agtattttga ttgaggaaat gccagaagac tttgaagtga
     4021 cagctcgttc gactgatgac caagccatca tggggattca acataaaaac ctaccgattt
     4081 atggcttcca gtaccatcca gagagcattg gaacgccaga cggcttgtct tctattcgga
     4141 attttatcga gaaggttgta aagtgaggaa actaggatga aagagattat tgaaaaacta
     4201 gcaaaatttg aaaatttatc aggtgtggaa atgacggatg tcattgagcg tatcgtaact
     4261 gggcgtgtaa ctgaagcgca gattgcttct ctcctcttag ctcttaagat gaagggggaa
     4321 acacctgaag aacgcacagc cattgcccaa gtcatgagag gacatgccca gcatattcca
     4381 actgagattc atgatgccat ggacaactgt ggtacaggtg gggacaagtc tttcagtttt
     4441 aatatttcca caactgcagc ctttgtcttg gctggtggcg gtattcacat ggccaagcat
     4501 ggtaaccgct cgatttcttc taaatctggt tccgcagatg tcctcgaagc cttgggaatc
     4561 aatcttgacc tcaaaccagc tgaactaggt aaggtctttg ataaaactgg aatcgtcttt
     4621 ctcttcgcta aaaatatgca cccagctatg aaatacatca tgccagctcg tttggaattg
     4681 ggaattccaa cgattatgaa cttgactggt ccactgattc atccaatggc tttagaaaca
     4741 cagcttcttg gaattagtcg tccagaactc ctagaaagta cagctcaggt tttgaaaaat
     4801 atgggtcgca aacgtgccat cgtggttgct ggaccagaag ggttggatga agctggcttg
     4861 aacggaacaa ccaagattgc acttcttgaa aatggcgaaa tcagcttgtc aagctttact
     4921 ccagaggatt tgggaatgga aggctatgct atggaagatg ttcgtggtgg gaatgctcag
     4981 gaaaatgcag aaattttgct tagcgttctg aaaaacgaag caagtccatt cttggaaacg
     5041 acagtcttga atgctggtct tggtttctat gctaatggta agattgatag catcaaggaa
     5101 ggagttgcct tggcccgtca agtgattgct agaggcaagg cccttgaaaa actcagactg
     5161 ttacaggagt atcaaaaatg agtcaggaat ttttagcacg aatcttagag cagaaggcgc
     5221 gtgaggtgga gcaaatgaag ctggagcaaa tccagcctct gcgccagacc tatcgcttgg
     5281 cagaattttt gaagaatcat caggaccgct tgcaggtaat cgctgaggtc aagaaagcta
     5341 gccctagttt gggagatatc aatctcgatg tggatattgt gcaacaggcc cagacttatg
     5401 aagaaaacgg agcagtgatg atttcggtgt tgacagatga ggttttcttt aaagggcatt
     5461 tgaattatct acgggaaatt tccagtcagg tagagattcc gacgctcaac aaagacttta
     5521 tcatagatga aaagcaaatc atccgcgctc gcaatgcagg tgcgacagtt atcttgctta
     5581 ttgtggcagc cttgtccgaa gaacgcctca aggaactgta tgactacgcg acagagcttg
     5641 gtctggaagt cttagtggag actcacaatc tagctgaact agaggtagcc cacagacttg
     5701 gtgctgagat tatcggggtc aacaaccgca acttgactac ctttgaggtc gacttgcaga
     5761 ccagtgtaga tttagcccct tactttgagg aaggtcgcta ttacatttct gaatctgcca
     5821 ttttcacagg gcaggatgcg gaacgactag ccccatactt taacggaatt ttggtaggga
     5881 cagctcttat gcaggcagaa aatgtggccc agagaatcaa ggagttgcag attgacaaag
     5941 gttaaaattt gtggactatc gaccaaagaa gcggtggaaa cagccgtttc agcaggagcc
     6001 gactatatcg gttttgtctt tgcacctagt aaaagacagg tgactttaga agaggcagct
     6061 gagttggcaa agcttattcc tgcagatgtg aaaaaggttg gagtatttgt ttcaccaagt
     6121 cgggtagaac tgctggaagc gattgacaaa gttggcttgg acttggttca agttcacggt
     6181 caggtggtag ctgatttatt tgagaatttg ccttgtgcca gtattcaggc tgtgcaggta
     6241 gatggaaatg ggcatgtccc caattctcag gcagattatc tactctttga tgcccctgtg
     6301 gcaggaagtg gtcagtcctt tgattggggt caactggata cgactggact agcacagccc
     6361 ttctttatcg caggtggcct taatgaagat aatgtagtaa aagcaattca acattttact
     6421 ccctatgcag tagatgtatc gagcggagtg gagacagatg gacaaaaaga tcatgaaaag
     6481 attagaagat ttatagagag ggtaaagcat ggcatatcag gaaccaaata aagatggatt
     6541 ttacggaaaa ttcggcggac gttttgtccc agaaacattg atgacagcag ttttggagtt
     6601 ggagaaggcc taccgtgaaa gtcaggcaga cccaagtttc caagaggaat taaaccagct
     6661 tttgcgccag tacgtaggac gtgaaactcc tctttattac gcaaaaaact tgacccagca
     6721 tatcggcgga gccaagattt atctcaaacg ggaagacctt aaccatacag gagcccacaa
     6781 gattaacaat gccttgggac aagtttggct tgccaaacgc atgggtaaaa agaaaattat
     6841 cgcagaaact ggtgctggtc agcacggtgt ggcaactgca actgctgcgg ccctctttaa
     6901 catggaatgt accatctaca tgggtgagga agatgtcaaa cgccaagccc tcaatgtctt
     6961 ccgtatggag cttttgggag ctaaggtcga ggccgtgaca gatggttcgc gcgtgctcaa
     7021 ggatgcggtc aatgcagccc ttcgttcatg ggtggctaat atagatgata cccactatat
     7081 ccttggttct gccttggggc ctcatccatt tccagaaatt gttcgtgact tccaaagtgt
     7141 cattggtcga gaggctaaac aacagtaccg tgacttgaca ggacaaaatc tgccagatgc
     7201 cctagtagcc tgtgttggtg gtgggtcgaa tgccatcggt ctcttccatc cctttgtaga
     7261 agatgagtca gtagccatgt atggagctga agcggctgga tttggtgtgg atacggagca
     7321 ccacgcagct accttgacca agggtcgtcc aggtgtcctt cacggttccc tcatggatgt
     7381 gctccaagat gcccatggtc aaattcttga agccttctct atctcagcag gtttggacta
     7441 tcctggtatc ggtccagagc attctcacta ccacgatatt aaacgtgcca gctatgtccc
     7501 tgtgacagac gaagaagcct tggaaggatt ccaactcttg tctcgtgtgg aagggattat
     7561 cccagctttg gaatctagcc atgctatcgc ctttgcggtg aaattggcca aagaacttgg
     7621 accagaaaag tctatgattg tatgcctatc aggtcgtggg gacaaggatg tggttcaagt
     7681 aaaagaccgc ttggaagcag atgcagcaaa gaagggagaa gctcatgcct aagacactaa
     7741 caaaaaaatt aaatgctatt aaagcagctg gaaaaggaat ttttgttccc tatatcatgg
     7801 ctggtgacca cgaaaaaggt ttggatggtc ttgctgaaac aattcacttt ttagaagatt
     7861 tgggtgtctc tgcaattgaa gtgggtattc ccttttcaga ccctgttgca gatggacctg
     7921 ttatcgaaga agctggcttg cgcagtttag cccacgggac ctctacccag gctttagttg
     7981 aaaccttgaa aaccattgaa acagagattc cactggtcat catgacctac ttcaaccccc
     8041 tctttcagta cggtgtggag aactttgtca aagatctggc tgatacagct gtgaagggct
     8101 tgattatccc agacctgcct catgaacatg ccaactttgt agaaccattt ttggcagata
     8161 cagatatcgc cttgattcct ttagtaagct tgaccacagg aattgagcgc cagaaagagt
     8221 tgattgaagg ggcggaggga ttcgtctatg ccgttgccat caatggggta acagggaaat
     8281 caggcaatta ccgtgcagat ttggacaagc acttggcgca acttcatcaa gtggccgaca
     8341 tcccagtctt gacaggtttt ggtgtatcta gtcaagccga tctggaacgc ttcaatgcgg
     8401 tgtcagatgg tgttatcgtc ggttcgaaaa tagtaaaagc tctccaccaa ggagagccga
     8461 ttcaggactt tatcaaacaa gcagtagctt accaaaaata attaaacaag tagcaagtaa
     8521 gaggaaaggc acgaaaggaa gtctttcctt tttcttttgc aggagaaagg ctagttttat
     8581 agtgaattga atctggaata ttacactacg gttcctaaaa tattttaaga aagtgatttg
     8641 aatttcccaa taaatttgtt
//
LOCUS       DAVKBK010000073         8353 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVKBK010000073 DAVKBK010000000
VERSION     DAVKBK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8353
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.073"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..243
                     /locus_tag="VWX69_001802"
     CDS             <1..243
                     /locus_tag="VWX69_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU9193098.1"
                     /translation="SCYREEQSGCLDMVVIQKQNEIEELSTNIEKKIMNYIFEDDGNV
                     SEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            256..1731
                     /gene="galT"
                     /locus_tag="VWX69_001803"
     CDS             256..1731
                     /gene="galT"
                     /locus_tag="VWX69_001803"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU9193099.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1744..2724
                     /gene="galE"
                     /locus_tag="VWX69_001804"
     CDS             1744..2724
                     /gene="galE"
                     /locus_tag="VWX69_001804"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9193100.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGLPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            2934..3593
                     /locus_tag="VWX69_001805"
     CDS             2934..3593
                     /locus_tag="VWX69_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU9193101.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3618..4685
                     /locus_tag="VWX69_001806"
     CDS             3618..4685
                     /locus_tag="VWX69_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9193102.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELASKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWGVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4788..5798
                     /locus_tag="VWX69_001807"
     CDS             4788..5798
                     /locus_tag="VWX69_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9193103.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5810..7501
                     /locus_tag="VWX69_001808"
     CDS             5810..7501
                     /locus_tag="VWX69_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9193104.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7504..8214
                     /locus_tag="VWX69_001809"
     CDS             7504..8214
                     /locus_tag="VWX69_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU9193105.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2835 a         1156 c         1643 g         2719 t
ORIGIN      
        1 tcttgttata gagaggaaca atctggatgt ttagatatgg ttgttataca aaaacagaat
       61 gagatagaag agcttagtac aaatattgaa aagaaaataa tgaattacat atttgaagat
      121 gatgggaatg tttctgaagt aattggtgct ttagatatta ttcatcacct tgataaaatt
      181 gctcatacta cgcaatcaat ttataaatgg ataatgtata gaaaatatgg gaacataaat
      241 tagaaagaaa aatatatgaa aacaattatt gataattttg ttgatagagt aattgaatac
      301 ggaatgtata atgaaattga caaaatatat gtgaaaaata gagtactagc gttaataggt
      361 gaggagggaa ctgatcgcat ttccgatgaa aatgacctga aacaaataaa agattactta
      421 gtggaaatcg ccttaaaaaa cggtaaaatt aaagatttaa tcgaggaaaa ggaatgttta
      481 ggagcagagt taatgaattt catagttcct ttacctagtc gattaaatga tattttttgg
      541 agttcatatg atatatcacc tcaagaagca gttgaagagt tttataagtt aagtaaagat
      601 agtgattata ttaaaacttc tgctattgct aagaatattg agtttcgagc atcaactaaa
      661 tacggagagc tagagattac gataaatttg tcaaaacccg aaaaagatcc aaaaacaatt
      721 gctgctgaaa aattagtaaa agccactaat tatcccaaat gtttactatg tatggaaaat
      781 gaaggatatc aggggcgaat aaattatcca gcacgttcga atcatagaat tattcgattg
      841 aaacttggtg acgaagtatg gggattccaa tattctccct acttatactt taatgagcat
      901 gcgatatttt taaatagtca acatgtacca atggctatta cctctaaaac atttgaacaa
      961 ttattggaga ttgttgatat tttgccagga tattttgctg gttcaaattc tgatcttcct
     1021 atctcaggag gctccattct tagtcataac cactaccagg gagggaaaca tattttccca
     1081 atggaaaaag caaaatttga gagtgaattt cgttttaaag actttgagga tgttaatgct
     1141 ggtattgtaa aatggccaat gtcagtaatt aggttacaaa gtgaaaataa aaatcgcttg
     1201 ttagatttag ctactaaaat tctaaataag tggagagaat attcagattt agaagtagac
     1261 atcattgcta tgactgaaga tgtcccacac catacggtga ctcctattgc tcgtaaagtg
     1321 gacgggagat atgaattaga tattgttcta agagataatc atactactga acagtaccca
     1381 gatggtgttt tccatcctca tcaagatgta caacatatta aaaaggaaaa tatcgggtta
     1441 atcgaagtga tgggacttgc gatattacca cctcgtttga aaccagagtt agaagaagtt
     1501 ggaaaatatc ttttaggaga ggataacgca attgcggatt atcatttaga atgggccgac
     1561 caattgaaag aaaaatatcc tcgcattaat aaagaagagg ttaatagcgt agttcaacac
     1621 gaagcaggac aagtgtttgc gagagttctg gaagatgcag gagtttataa gaatacaccg
     1681 tctgggcatg aagcgtttat gagatttgtt aagtcggttg gaattaatta ggaggaaaca
     1741 aaaatggcaa tattggtaac aggcggagct ggttatattg gtagccatac cgtagtagaa
     1801 ttactaaatt taggaaagga agtcatcatt gtcgacaacc tttcgaactc tagcatcttg
     1861 gtgctagacc gtattgaagc aattacagga atacgtcccg tgttttacga attagatgtt
     1921 tgtgataaac cagcattgag aaaggtattt gaacaagaat cgattgatgc tgcaattcat
     1981 tttgcaggtt ataaagctgt cggagaatcc gtgcaaaagc ctgtgatgta ctacaaaaat
     2041 aatattatga gtacattggc acttgttgaa gtgatgtcag aatttaatgt taaaaagatt
     2101 gtcttttctt caagtgcgac tgtatatgga attaacaatc agtcacctct aattgagacg
     2161 atgcaaacaa gtgcgacaaa tccttatggg tatacgaaag tgatgcttga gcaaatttta
     2221 aaagatgttc atgtggcaga ttcagaatgg agtattgcgt tgcttcgtta tttcaatcca
     2281 attggtgctc atgagtctgg tttgattggg gaagatccct caggacttcc taacaacttg
     2341 atgccttata ttgcacaagt agcggtaggt aagctatcag agctaagtgt gttcggaaat
     2401 gattatgata cgcttgatgg tactggtgtg cgtgattata tccatgtagt agatttagca
     2461 ataggacata taaaagcttt agaaaaagta tctgaaaaaa cagatgttta tatctataac
     2521 ctaggctcgg gagaaggcac tagtgtatta caacttgtaa atacatttga aagtgttaat
     2581 aagatcccta ttccttataa aatagttcca agacgttcag gagacgttgc aacttgttat
     2641 gcaaatgcag acaaagcata taaggaatta aattggagga caacaaaatc gattgaagac
     2701 atgtgtagag atacatggaa ttagcaatca aaaaatccca atggctataa ttgatgatac
     2761 tgtctatatg agtgctgtat tttggaaaaa ttacttaacc ttttaatgaa atgcatattt
     2821 aatgaaagat aaattaaaaa aaatgtttga cagcgcttga caaaggaaac ggtttcattg
     2881 tataatgtaa acatagtgac accgatgtca aatataaaaa agaaggtctt tatatgaaaa
     2941 acttaacaaa aattaagttc aaagaaaatg gggaatttaa tcatttccct gggaatacag
     3001 ttgtagcaaa tctttatact aaacaagatt tgatggaagt tgttgatatt attcaatcac
     3061 gttatagaga attaccattt atcgataagt ttactttaac tccaaggaat tctattcaca
     3121 tgactgtaat tgaattgttg tgccatgaaa atcgtgaaac ggagttttgg agcagtaatc
     3181 ttcctctaga tacaccttta caggaaatac atgattactt tgctaaacaa cttgaaattt
     3241 ttccattgtt ggatgaagaa attcatatgc gtataactga aatgggaaaa caaaacatac
     3301 tagttgaacc tgcagatgaa gcttctgcaa agagattaga agaaattcgt acttatgtct
     3361 cagaaaaagc aggtgtttgt ttccctaatc atgatagata tcaattccat atttcaattg
     3421 ggtatcttcg gattcctcta accgaagagg aggaagaaga gtttactaaa gtcagagcag
     3481 aattaactga aattttatta gagaagattc caactattac tgtaaaccgt attgactata
     3541 ctgtatttga agatatgaga caatttgttc catatcacga aaaatttaaa taaaataata
     3601 aaaaaggaga acttatcatg aaaaaaatga aagtttggtc tactgtactt gcaacgggag
     3661 ttgctcttac tacacttgct gcttgctctg gaggttcaaa ttctacgact gcttcttcat
     3721 ctgaagaaaa agctgataaa agtcaagaat tagttatcta ttcgaactca gtctcaaatg
     3781 gtcgtggtga ttggttaact gctaaagcaa aagaagctgg ttttaatata aaaatggttg
     3841 atatcgctgg cgctcaatta gcagaccgtg ttattgctga gaagaataat gcagttgcag
     3901 atatggtatt tggaattggt gctgttgact caaataaaat tagagatcaa aaattactag
     3961 tacagtacaa gcctaaatgg ttagataaaa ttgatcaatc tttatcagat aaagataatt
     4021 attataatcc tgtgattgtt caaccattag ttttaattgg ggcgcctgat gtaaaagaaa
     4081 tgcctaaaga ctggacagag ttagctagta agtataaagg taaatattca atttatggtc
     4141 ttcaaggtgg tacaggacgg gcaattctag caagtatctt agttcgttac cttgatgaaa
     4201 aaggagattt aggcgtatca gaaaaaggat ggggagttgc aaaagaatac tttgcaaatg
     4261 cctatactct tcaaaaaggt gaaagctcag ttgttaaagc gttagataaa gaaagcccaa
     4321 ttcaatacgg tatgatctgg ggttctggag cgttaatcgg acaaaaagaa caaaatgttg
     4381 aattcaaagt tatgactcct gagattggtg taccatttgt aactgaacaa actatggttt
     4441 taagcactag taaaaaacaa gcgttagcta aagaatttat tgattggttt ggtcaatcag
     4501 aaattcaagt agaatatagt aaaaaatttg gatctattcc tgcaaataaa gatgccctaa
     4561 aagagttacc tgaagatacg aaaaaatttg ttgatcaagt gaaaccacaa aatattgact
     4621 gggaagctgt tggaaagcat ttggatgaat gggtagaaaa agctgaatta gaatacgtaa
     4681 aataagaaat aagagttatt ttttatgtcc aagtctctct attatttcta aatttaagga
     4741 agaaataaag agaggctttt ggtttagtaa tagagggagt tagtgagatg attaaatttg
     4801 ataatattca aattaaatat ggtgattttg ttgcaattga taatctgaat ttagatatac
     4861 atgaagggga attctttaca tttcttgggc cttcaggatg tggtaaatca actactttga
     4921 gagcattggt aggtttttta gatccatcat caggaagtat tgaagttaat ggaacagatg
     4981 tcactcattt ggaacctgaa aagcgtggaa ttggtattgt atttcaatct tatgcgctat
     5041 ttccaactat gactgttttt gataatattg catttggttt aaaagttaag aaggtagctc
     5101 cagatgttat taaagctaaa gtatcagcag tggcagcaaa aattaagatc tctgatcaac
     5161 agttacagcg taatgtatca gaattatctg ggggtcaaca acaaagggta gcattggctc
     5221 gtgctctggt tcttgaacct aaaattcttt gtctagatga accattgtca aaccttgacg
     5281 caaaattacg tgtagatttg agaaaagagt tgaaaagact tcaaaaagag ttaggtatta
     5341 ctactttata tgttactcat gatcaagagg aagccttgac tttatctgat agaattgcag
     5401 tctttaacaa tggatacatc gaacaggtcg gtacaccagt agagatttat cataattctc
     5461 aaactgaatt tgtatgtgat tttattggag atattaatgt tttgaccgat gaaacagtcc
     5521 acgaagtatt actgaaaaat acaagcgttt tcttagagga taaaaaaggt tacattcgat
     5581 tagagaaagt tcgattcaat cgtgaaactg aacaagattt tattctaaaa gggacaatta
     5641 ttgatgttga gttttctgga gttacaattc actatacaat aaaagtttct gaaagtcaga
     5701 ttcttaatgt aacaagtatt gatagtcagg ctgctattag atctgtcgga gaaagtgtgg
     5761 aattatttat cacaccatca gacgttctgc aattttaagg aggtgcagta tgcgtcataa
     5821 attaaattta aaagattggc ttattcgttt agggttaatc tggttcttag taacatttat
     5881 tatttatcca aactttgatc tagtagtgaa tgtatttgta aaaggaggag aattttccct
     5941 tgatgctgta catcgtgttc taaaatctca gagggcactt cagagtatta tgaacagttt
     6001 taagttagca ttttcactca ttattacagt taatgtcgta ggtattcttt gtgttctatt
     6061 tacagagtac tttgatatta aaggtgctaa aattttaaaa ttaggttata tgacctcttt
     6121 aatttatgga ggagtggttt tagcgactgg atataaattt gtctatggtc cttatggatt
     6181 gattacaaaa tttttacaaa atgttatccc ttctttagac tctaactggt ttattgggta
     6241 tggtgcagtc ttattcatta tgacattttc aggaactgct aatcatacat tgtttttaac
     6301 aaatacaatt cgaagcgttg actatcacac tattgaggct gctcgaaata tgggagcaaa
     6361 accatttact gttttccgaa aagtagtgtt accaacctta attccaactc tatttgcact
     6421 tactattatg gtttttctta gtggtttatc tgcagtagca gcacccatga ttgttggtgg
     6481 taaagaattt caaactataa atccaatgat tattacattt gcagggatgg ggaattctcg
     6541 tgatttagct gccttacttg caattatttt aggtattgca actacaattt tgcttactat
     6601 catgaataag atagaaaaag gtggaaatta tatttctatc tctaagacta aagcgcctct
     6661 taaaaaacaa aaaattgcgt ctaagccttg gaatatcatt gctcacattg tagcatatgg
     6721 attgttcaca gttttcatgc ttccactaat ttttatagta ttatactcat ttacagatcc
     6781 agttgcaatt caaacaggta acttaacatt atcaaacttt actttagaaa attatcgctt
     6841 attctttagt aatagtgcgg cattctctcc attcttggtc agctttattt attctattat
     6901 tgctgcgaca acagcaacaa ttctcgcagt tgtatttgct cgtgttgtca gaaaacataa
     6961 atctcgtttt gatttcttat ttgaatatgg tgctctactt ccttggttac taccaagtac
     7021 acttttagca gtaagtttat tatttacttt taatcagcca caatttcttg tcttgaatca
     7081 gattttggta ggtagtttgg taattctact tattgcatat atagttgtaa aaatcccatt
     7141 ttcttataga atggtacgtg ctattttatt tagtgttgat gatgagatgg aagatgcagc
     7201 aagaagtatg ggtgcttcac ctttttatac tatgatgaag gttatcattc catttatttt
     7261 accggttgtt ctctctgtta ttgctttaaa ctttaactct ttattaactg acttcgactt
     7321 atctgtattc ctttaccatc ccctagctca accattaggt attacgattc gatctgcagg
     7381 tgatgaaaca gcaacatcta atgcacaagc tctggtattt gtttatacaa ttgttctgat
     7441 gatcatttct ggaacggtat tatacttcac acaaagaccg gggcgtaaag taaggaaata
     7501 atcatgacag ccactagtct tgggttatca aatattgaaa tagttgtcag gattgtttta
     7561 tcagtagtca ttggtagtat aattggttta gagagaggga gcaaatccca gcctgcaggc
     7621 atccgaactt atagtattgt ttgtctagct gcatgtttga ttatgatgac gaatgaatac
     7681 gtatcttata aatttgggac aggagatcct acacgattag gagctcaagt tatatcaggt
     7741 gtgggttttc taggcgctgg aacgattctt attacagata aaaagaaaat tacaggtctg
     7801 acaactgcag caggcatttg ggcttcggca ggaattggat tagctattgg agtaggtttt
     7861 tatgagggag ctcttttagt agccatttct gtttggggtg tgatatccat gttccaacca
     7921 ctaaaaaaat atctgcaaaa tcgttctaaa atgattgaat tgtatatagt ggttaaatct
     7981 acagaagcct ataatcgtgt attggtttat tgtgcagaaa atggtatcag aatgaccgat
     8041 tcaagaacag cgtttggaga tgttaattct gacagaattg aatactttga tgttccggac
     8101 aaaaaaatag cgtcatttat tactctggaa ttatcaggta gatttgaaca tcttcgactg
     8161 atggaagaaa ttgctaatat tgtaggtgtt atttatgtcg aagaaattag ctgaaattta
     8221 gtaaacaaag ggacagatgt ttttgtcctt ttgtttttta gatgttttaa tcatctaatt
     8281 tttgagtaga tttttgctca gaggttttta tgaaagatta taaaatcaat tttgatttag
     8341 gtaaaataga ata
//
LOCUS       DAVKBK010000074         8233 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVKBK010000074 DAVKBK010000000
VERSION     DAVKBK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.074"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            116..1597
                     /locus_tag="VWX69_001810"
     CDS             116..1597
                     /locus_tag="VWX69_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9193106.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1959..2960
                     /locus_tag="VWX69_001811"
     CDS             1959..2960
                     /locus_tag="VWX69_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9193107.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     KVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3111..4028
                     /locus_tag="VWX69_001812"
     CDS             3111..4028
                     /locus_tag="VWX69_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9193108.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAVRLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4039..4929
                     /locus_tag="VWX69_001813"
     CDS             4039..4929
                     /locus_tag="VWX69_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9193109.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4958..6574
                     /locus_tag="VWX69_001814"
     CDS             4958..6574
                     /locus_tag="VWX69_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9193110.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6584..7903
                     /locus_tag="VWX69_001815"
     CDS             6584..7903
                     /locus_tag="VWX69_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9193111.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
BASE COUNT         2763 a         1289 c         1558 g         2623 t
ORIGIN      
        1 ttattatacg aaataaaaga ttttaggaaa agtcgttata tcatgctata cctattcttt
       61 gtggtataat tgcaagaggt ttaatccgat aatttataaa gagagaaaga tattcatgag
      121 agatttatta tctaaaaaaa gtcataggca attagaatta ttagaattat tatttgaaca
      181 taaacgttgg tttcatcgtt ctgaactagc agagttatta aattgtacag aacgtgcagt
      241 caaagatgat ctatcccatg ttaaatctgc ttttcctgac ttgatttttc attcttctac
      301 taatggtata cgcattatta ataccgatga tagtgatatt gaaatggttt accatcattt
      361 ctttaaacat tcaactcatt tttcgatttt agaattcatc ttctttaatg aaggttgtca
      421 agctgagagt atttgtaaag aattttatat cagttcatct tcgctctatc gtattattag
      481 ccaaatcaat aaagtgatta aaaggcaatt tcaatttgaa gtcagtctga cccctgttca
      541 aatcattgga aatgagagag acattcgtta cttttttgca caatattttt cagaaaaata
      601 ttatttccta gaatggccat ttgaaaattt ttcatcagag ccactatctc aattgttaga
      661 attggtttat aaggaaacaa gctttccaat gaatttgtca acgcatagaa tgctaaagtt
      721 gctcctagtt acgaacctat atagaataaa gtttggtcat tttatggaag tagataaaga
      781 ttcttttaac gaccaaagtt tggatttttt aatgcaggca gaaggaatag aaggtgttgc
      841 tcagagtttt gaatcagaat acaatatctc tttagatgaa gaagttgttt gccaattatt
      901 tgtgtcttac tttcaaaaaa tgtttttcat agatgaaagt ctctttatga aatgcgtaaa
      961 aaaggatagt tatgttgaaa aatcttacca tctattgagt gattttattg atcagatttc
     1021 agtcaagtat cagattgaaa tggagaataa ggataatctg atttggcatc tgcataatac
     1081 cgcacatctg tatcgtcaag agttgtttac tgagtttatt ttatttgatc aaaaagggaa
     1141 tacaatcagg aactttcaaa atatttttcc aaaatttgtt tcagatataa aaaaagagct
     1201 ttctcactat ttagagactc ttgaggtttg ttctagttca atgatggtaa atcatctatc
     1261 ttataccttc atcactcata ccaaacattt ggtgattaat ttgctacaaa atcagcctaa
     1321 actaaaggtt ttagttatga gtaattttga tcagtatcat gcaaaattcg ttgcagagac
     1381 actttcttat tactgtagca ataattttga actggaagtt tggactgaat tagaattatc
     1441 aaaggaatct ttagaagatt caccttatga tatcattatt tctaatttta ttattcctcc
     1501 tattgaaaat aagagactca tctattcaaa taatataaac acggtctcac tcatatactt
     1561 gttaaatgcc atgatgttta ttcgattaga tgagtaacca aaaataacaa aaaaacgcta
     1621 tttcgcgttt gaactgtacc tcaaaagtta gacagaaaaa atctaatttt tggggtgttt
     1681 ttgttaagaa aagaccttca atcatttaag caaaatgtac atctagattt atagccctct
     1741 aaaactcttg ctttttttgt agaagatacg aaaaaagcca taaaaccaag gcttttcctg
     1801 ttttatgtag atgtttacac atgaaaattg aagtattttc aaaagctaat tggagtgatt
     1861 ttattcatga tgggataaat gatctggcca aaaatgattg agaaatagtt gcttaaaaag
     1921 catttgcatg atactatata ttgaaaggag gtgataatat ggtagaacaa agaaaatcaa
     1981 ttaccatgaa agatgttgct ttagaagcag gagttagtgt tggaactgtt tcacgtgtaa
     2041 ttaataaaga aaaaggcatt aaagaagtaa ctttgaaaaa agtggaacaa gcgattaaaa
     2101 ctttgaatta cattccagat tactatgcta gaggaatgaa aaaaaatcga acagaaacga
     2161 ttgcaatcat tgtaccaagt atctggcatc ccttcttttc agaatttgct atgcatgtgg
     2221 aaaatgaagt ctataagaga aataacaaat tactcttatg ttctataaat ggtacaaata
     2281 gagagcaaga ctatctggag atgttgcgtc ataataaagt tgatggagtg gttgccatta
     2341 cctatagtcc aattgaacat tacttgacgt caggaattcc ctttgttagt attgaccgca
     2401 catactcaga tattgccatt ccttgtgttt catcagataa tgatgcaggt ggaagagaag
     2461 cagctaaaca attaattagt aaaggatgtc agcatttagc ctttgtgggc ggacataata
     2521 caaccattaa tgaaaccaaa cgtcgtagaa tttcatttga aaagtatgtc caagagcata
     2581 aaatacctct tagtattttt gatttggatg agaaagttac tgactattat ggaaagctag
     2641 agagtttctt ggaagaaaat tcttctatag atggaatttt tacaatcaac gattttacag
     2701 ctttggatgt gattgaaata ctagaaaaaa atggcaaacg tattcctcat gatgtccaaa
     2761 ttattggata cgatggaatt aaaatggctg gagatagaga ttatctactt tcaactattg
     2821 aacaaccatt ggaagaaatg gcaaaagaag cggttcgtat tttgtttgat ataattgatg
     2881 gaaagactgt taatttgcag acaatcctac cagtaaaatt tgttgaagga aaaacaacaa
     2941 aaaatgaaaa taagtcttga cagaaagcgc tatcaatgat agaatgaatt cagataaaaa
     3001 gatttatttt taaaacaaaa atgaaacgtt tcaaaaaaag aaataaaaag acagcgccaa
     3061 gcgctatctt ttatagaaaa aatgaaacgt ttcaaaaaaa ggaggttgct atgaatagca
     3121 aagcgaagca agtttctctt tgggaaagaa tcaagaaaca aaaactcttg ttattgatga
     3181 ctgtccccgg tttagtttta acctttatct ttaaatacat ccctatgtat ggggttttaa
     3241 tcgcatttaa agattacaat cctttaaaag gaattttagg gagtgattgg attggttttt
     3301 ctgagtttac aaaattcata tcctctccca actttggtat cttgttagcc aacacattaa
     3361 aattaagtat ctatggttta ttgcttggct ttttaccacc aatcattctt gcgattatgc
     3421 tcaatcaact cttgagtgaa aaagtcaaaa aacgaattca gctcatttta tacgcaccaa
     3481 actttatctc agtcgttgtt attgtcggta tgattttcct cttcttttca gtgggaggac
     3541 caatcaacaa ttttctttct atgtttggaa tgaaggctga cttcttgaca aatccagact
     3601 tctttagacc cttatacatc tttagtggta tctggcaagg aatgggctgg gcttcaacgc
     3661 tctacacggc aacattggta aatgtagatc cagccttagt agaagcagtt cgactggatg
     3721 gagccaatat cttccaacga atctggcaca ttgatattcc agctcttaag cctattatgg
     3781 ttatccaatt tgttttagct gcaggtggaa ttatgaatgt cggatatgaa aaagcattct
     3841 tgatgcagac atcgttaaat ttgccaactt ctgaaattat ctcgacatat gtctataaag
     3901 ttggtcttgt atcaggagac tattcttact caacagcggt tggtttgttt aatgcagtga
     3961 ttaacgtagt attgcttgtt gcagttaacc aaatcgttaa acgcatgaat aatggtgaag
     4021 gaatttaagg aggaaagtat gaaaaattcg attatggata caaaatttga tagacgtatc
     4081 ttactcttaa ataaaatcat tattgtcttt atcgttttga tgactttgct tcctttactt
     4141 tatatcgtcg tagcatcctt tatggatcct aaggttctgg ttagtagagg gattagcttt
     4201 aatccagccg attggactgt agaaggttac cagcgtgtat tcagtgacca atctattcta
     4261 agaggtttta tcaattctct actatactct tttggatttg cagctttaac agtattgcta
     4321 tctgtgttta cagcttatcc tctttctaag aaagacttgg ttggacgtcg ttggattaac
     4381 tacttcttga ttgtgactat gttctttggt ggtggtttag tcccaactta cttgctcgta
     4441 aaagaattgg gaatgctcaa tactccatgg gctatcattg ttccaggtgc tgtcaatgtt
     4501 tggaatatta ttcttgctag ggcctatttc caaggattgc ctgaagaatt agttgaagct
     4561 gctgtcattg atggagcgaa tgacttgcag attttcttta aaatcatgct tcctcttgca
     4621 aaaccaatta tgtttgttct cttcctctat gcttttgtag gacagtggaa ctcatacttt
     4681 gatgcaatga tttatatcaa ggatccaaac ttggaaccat tgcaacttgt acttcgtaaa
     4741 attctcattc agagccaacc aggtcaagac atgattggag cacaagcggc tatgaatgaa
     4801 atgaaacgtt tagctgaatt gattaaatac gcaactattg tcatttccag cttgccattg
     4861 attgttatgt atccattctt ccaaaaatac tttgataaag gaattatggc tggttcactt
     4921 aaaggataaa aaaagaaaaa ataaaaggag ttttctcatg aaattcaaaa cattctcaaa
     4981 atcagcagtt ttgttgacag ctagtttagc agtacttgca gcctgtggct caaaaaatac
     5041 agcttcaagt ccagattata agttggaagg tgtaacattc ccgcttcaag aaaagaaaac
     5101 attgaagttt atgacagcca gttcaccgtt atctcctaaa gacccaaatg aaaagttaat
     5161 tttgcaacgt ttggagaagg aaactggcgt tcatattgac tggaccaact accaatccga
     5221 ctttgcagaa aaacgtaact tggatatttc tagtggtgat ttaccagatg ctatccacaa
     5281 cgacggagct tcagatgtgg acttgatgaa ctgggctaaa aaaggtgtta ttattccagt
     5341 tgaaaatttg attgataaat acatgccaaa tcttaagaaa attttggatg agaaaccaga
     5401 gtacaaggcc ttgatgacag cacctgatgg gcacatttac tcattcccat ggattgaaga
     5461 gcttggagat ggtaaagagt ctattcacag cgtcaacgat atggcttgga ttaacaaaga
     5521 ttggcttaag aaacttggtc ttgaaatgcc aaaaactact gatgatttga ttaaagtcct
     5581 agaagctttc aaaaacgggg atccaaatgg aaatggagag gctgatgaaa ttccattttc
     5641 atttattagt ggtaacggaa acgaagattt taaattccta tttgctgcat ttggtatagg
     5701 ggataacgat gatcatttag tagtaggaaa tgatggcaaa gttgatttca cagcagataa
     5761 cgataactat aaagaaggtg tcaaatttat ccgtcaattg caagaaaaag gcttgattga
     5821 taaagaagct ttcgaacatg attggaatag ttacattgct aaaggtcatg atcagaaatt
     5881 tggtgtttac tttacatggg ataagaataa tgttactgga agtaacgaaa gttatgatgt
     5941 tttaccagta cttgctggac caagtggtca aaaacacgta gctcgtacaa acggtatggg
     6001 atttgcacgt gacaagatgg ttattaccag tgtaaacaaa aacctagaat tgacagctaa
     6061 atggattgat gcacaatacg ctccactcca atctgtgcaa aataactggg gaacttacgg
     6121 agatgacaaa caacaaaaca tttttgaatt ggatcaagcg tcaaatagtc taaaacactt
     6181 accactaaac ggaactgcac cagcagaact tcgtcaaaag actgaagtag gaggaccact
     6241 agctattcta gattcatact atggtaaagt aacaaccatg cctgatgatg ccaaatggcg
     6301 tttggatctt atcaaagaat attatgttcc ttacatgagc aatgacaata actatccaag
     6361 agtctttatg acacaggaag atttggacaa gattgcccat atcgaagcag atatgaatga
     6421 ctatatctac cgtaaacgtg ctgaatggat tgtaaatggc aatattgata ctgagtggga
     6481 tgattacaag aaagaacttg aaaaatacgg actttctgat tacctcgcta ttaaacaaaa
     6541 atactacgat caataccaag caaacaaaaa ctagaggttg attatgggag ataagaaata
     6601 cacagtagaa aaagccaatc gttttatagc agaaaataaa catctcgtta atactcaata
     6661 taagcctgaa gaacattttt cagctgagat tggttggatc aatgatccaa atggatttgt
     6721 ctattttcgt ggagaatacc atctctttta tcaattctat ccatatgata gtgtttgggg
     6781 gcctatgcac tggggacatg ctaaaagtaa ggacttggtg acttgggagc acttgccagt
     6841 ggcacttgct cctgaccaag attatgaccg aaatggttgt ttctcaggct ctgccattgt
     6901 caaggatgat cgcctctggc tcatgtacac tggacatatc gaagaagaaa ccggtgtccg
     6961 ccaagtgcaa aatatggcat tttcagatga cgggattcac tttgaaaaga ttgaacaaaa
     7021 tccagttgca actggatcag acttgccaga tgagttgatt gctgctgatt ttcgtgatcc
     7081 aaaactcttt gaaaaagatg gacgctatta ctccgtagta gctgccaaac acaagaataa
     7141 tgtgggctgt atcgttctac tagggtccga taacctagta gaatggcagt tcgaatccat
     7201 ctttttaaaa ggggtagaac accaaggctt tatgtgggaa tgcccagatt acttcgagtt
     7261 agatgggaaa gattgcctta ttatgtcacc catgcgttat cagcgtgagg gagactcata
     7321 tcataacatc aactcatcgc ttttgttcac gggtaaggta gattggggag aaaaatgttt
     7381 tatcccagaa tcagttcaag aaattgatca tggccaagac ttctatgcgc ctcaaacatt
     7441 gttggacgat caaaatcgtc gtatcctgat tgcttggatg cagacatggg ggcgtaccct
     7501 tccaacccat gaccaagaac acaaatgggc atgtgccatg actttaccta gaattttaag
     7561 attggaagat ggcaaactaa gacaattccc tgttaaaaaa ggccaatatc aaatccaaat
     7621 agataaagat tgtcattacc acttaggaaa tgatatagat tatcttgaat ttggttatga
     7681 tagtaatgcg cagcaagttt acattgatcg tagccatctt attcaaaaaa ttctaggtga
     7741 agaagaacag gacactagtc gacggtatgt agatattgaa gctaaagaat tggaagttgt
     7801 tctagataaa aattccatcg agatttttgt caatcaaggt gaagcaagct tgactgcaac
     7861 ttattactta acggtgccag ctgagctatc acgaattgat taaaaattaa gttatttctc
     7921 ctaaagaaaa agttctcttt ctaaaatagt ggaaagagga ctttttgtgt tttgggtata
     7981 taagcttagt ttatggtatt tgtaaaattg gtgttggatt atgatttaag ctagttttct
     8041 aaagaatttg aaaaaaattt tatttaagca aaaaaaaccc ttggttccaa ggcttttcct
     8101 gttgtattta tatgccccct acaagtatat tatgatacat agtattaagt gattatttat
     8161 ttttgaggct tttcttattc taaaagtagg tatatgagtt tatggacatt gtaattcaca
     8221 acaaattcac ggc
//
LOCUS       DAVKBK010000075         7950 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVKBK010000075 DAVKBK010000000
VERSION     DAVKBK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7950
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.075"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(164..304)
                     /locus_tag="VWX69_001816"
     CDS             complement(164..304)
                     /locus_tag="VWX69_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HEU9193112.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQVTADDIRLQELLNTTMQELKKQ
                     KS"
     gene            473..1015
                     /locus_tag="VWX69_001817"
     CDS             473..1015
                     /locus_tag="VWX69_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU9193113.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            1015..1644
                     /gene="nth"
                     /locus_tag="VWX69_001818"
     CDS             1015..1644
                     /gene="nth"
                     /locus_tag="VWX69_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU9193114.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            1855..2376
                     /gene="pyrR"
                     /locus_tag="VWX69_001819"
     CDS             1855..2376
                     /gene="pyrR"
                     /locus_tag="VWX69_001819"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU9193115.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            2395..3318
                     /locus_tag="VWX69_001820"
     CDS             2395..3318
                     /locus_tag="VWX69_001820"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU9193116.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            3368..4447
                     /gene="carA"
                     /locus_tag="VWX69_001821"
     CDS             3368..4447
                     /gene="carA"
                     /locus_tag="VWX69_001821"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU9193117.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            4759..7935
                     /gene="carB"
                     /locus_tag="VWX69_001822"
     CDS             4759..7935
                     /gene="carB"
                     /locus_tag="VWX69_001822"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU9193118.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         2300 a         1610 c         1795 g         2245 t
ORIGIN      
        1 acaggtccat agagacttag tacgtgtttg acatactcgt aatggatttt atcatagttt
       61 cgccaagcag tgcgtgcttg attgtttagt tttaggctac ccagtccaat cagaggactg
      121 gtgggttggt aaaatttctc aagattaatt aagatactgt tgttcaactt ttctgttttt
      181 tgagctcttg catagtagtg tttagcagct cttgtagtcg aatatcatct gccgtaacct
      241 gtttacagtt ttggtagctt ttatttaact tggataggag ttgaatgagt ttcttgtctt
      301 ccatgtgagc atcctccttg atctgatgta ctctttccct atagtatagc actaaaaaat
      361 aaaactatca tagtaaatat gttaaaattt gaattttaat tacaaagttt ggtgtgctga
      421 tttgtagcct tttcatggta taatcaagag agtaaatctt tatggaggaa gtatgaaatt
      481 aaatattcaa gaaattcgta agcagtctga aggtttgaac tttgaacaaa cgttagattt
      541 agttgatgac ctgcgtgcac gtaatcaaga aattttagat gtaaaagata tccttgcagt
      601 tgggaaagta caatatgaag accgtatgta tttcttagat tatcaactat cttataccat
      661 tgttcttgct tcgagtcgca gtatggagcc agttgagtta gttgaatctt atccagtcac
      721 ggaagttttc atggaaggcg caactaacca gctagatcaa gaagttttag atgatgactt
      781 ggtcttgccc atcgaaaatg gggcgcttga ccttgctgag agtgtatcag acaatatcct
      841 gctaaacatt cctatcaagg tcttgacggc tgaagaagaa gctggtcaag gatttgtctc
      901 aggaaatgac tggcaaatca tgacagagga agaataccaa gctcaacaag cagtaaagaa
      961 agaagaaaac agtccttttg ctggcttaca aggactattt gacggagatg aataatggtc
     1021 ttgtcaaaaa aacgagcacg aaaggtgcta gaagaaatca ttgccctctt cccagatgcc
     1081 aagcctagtc ttgattttac caatcatttt gaactcctgg ttgcggtcat gttatcagcc
     1141 cagacgacag atgcagcggt aaataaggcc acaccaggtc tctttgttgc ctttccaaca
     1201 ccccaagcta tgtctgtagc gacagagagt gagattgctt cacatatttc tcgcttggga
     1261 ttgtatcgga ataaagctaa attccttaaa aaatgtgccc aacagttact agacgatttt
     1321 gatggtcaag tccctcagac acgtgaagaa ttggagagtt tggcaggtgt tggtcgcaag
     1381 acagccaatg ttgtcatgag tgtaggattt gggattccag cctttgcagt ggatactcat
     1441 gtggagcgta tttgcaaaca ccacgatatt gtcaaaaaat cagcgacgcc acttgaggtg
     1501 gaaaagcggg tcatggatat cttgccgcct gagcagtggt tagctgccca tcaggccatg
     1561 atttattttg gaagagccat ttgccatcca aaaaatccag agtgtgacca gtacccacaa
     1621 ttatatgatt ttagcaattt gtaagatgct acattgaaac tttttgcttg attttaagca
     1681 tgctttgtgc tatagtaaat gataactaaa tattccttta aacctgtccc gtgaggcagg
     1741 caaggagcgc gataaagtag aagggtgaag tctacactgt gtgcagtagg gctcgcttgg
     1801 ctataaattt caagtctcct tgtttaagga gacttttctt tttggaggtt tgtcatgaaa
     1861 acaaaagaag ttgtagacga attgaccgtc aaacgagcga ttacgcgtat tacttatgag
     1921 attatcgaac gcaacaaaga tttgaataag atcgtcttgg ctggtattaa aactcgtggt
     1981 gtctttattg cccaccgaat ccaagaacgt ttgaagcagt tagaaaatct ttcagttcct
     2041 gttgtggaat tggatactaa acctttccgt gatgatgtta aaagtggaga agatacttct
     2101 ttggtttctg tcgatgtgac agaccgcgaa gttatcttgg tggatgatgt gctctataca
     2161 ggtcgtacca tccgtgctgc tattgataat attgtcggtc atggtcgtcc tgcgcgtgtg
     2221 agtttagcag ttctagtcga tcgtggacat agagaattgc caatccgtcc agattacgtt
     2281 ggaaaaaata tcccaaccag tcgttctgaa gaaatcatcg tagagatgac agaacttgat
     2341 gaccaagaca gagttctgat tactgaagaa gcttagaaag ttaaaggagt agccatgtca
     2401 gaaaatcaac aagcattgaa ccatgtggtg tccatggaag acctcactgt cgatcaagta
     2461 atgaaattga tcaagcgagg aattgagttt aaaaatggag cccagcttcc ctatgaagac
     2521 catccgattg tttccaatct cttctttgag gattctacac ggacacataa gtcctttgaa
     2581 gtcgcagaga ttaaacttgg attggaacga cttgactttg atgtgaagac tagttcggtt
     2641 aataagggtg agacacttta tgacaccatt ttgactctgt ctgctttagg agtggatgtc
     2701 tgtgtgattc gccatccaga ggtcgactac tatagagaat tgattgctag tccaacgatt
     2761 acgacttcca tcatcaatgg tggagatggt tcgggccaac accctagcca gagcttgctt
     2821 gatttgatga ccatttatga ggaatttggc cactttgagg gtcttaaagt tgctattgca
     2881 ggtgacttgg atcactcacg cgttgccaaa tccaatatgc agattttgaa acgcttggga
     2941 gctgaactct ttttcgctgg acctgaggaa tggagaagtc aagagtttgc agactatgga
     3001 cagtttgtaa ccattgatga aatcattgat caggttgatg tcatgatgtt tctccgtgtg
     3061 caacacgaac gccatgatag tggagctgta ttttcaaaag aagactacca tgcccaacat
     3121 ggcttgactc aagaacgtta cgatcgtttg aaagaaacag caatcctcat gcacccagct
     3181 ccaatcaatc gtgatgtaga aatagcagac cacttggttg aagcaccaaa atcacggatt
     3241 gtccaacaaa tgaccaatgg tgtctttgtt cgaatggcaa tcttagaatc cgtactagcg
     3301 agtagaaacg ccaactaaaa cacaagacgt taaaagacgc cagtgagcgt ccacgagagg
     3361 tgaaaatatg acaaaaagaa ttctagtatt agaagatggc acagtttttg aaggcaaggc
     3421 cttcggagca gatattgatg taacaggcga aatcgtcttt aatacaggga tgaccggcta
     3481 ccaagaatcc attacagacc agtcttataa tggacaaatc ttgaccttta cttatccttt
     3541 ggtaggaaat tatggtatta atcgtgatga ttatgaatcc attattccaa cttgtaaggg
     3601 agtcgttgtt tttgaagaag cgcgtagagc tagcaactgg cgcaaccaaa tgaccttgga
     3661 tgaatttttg aaagccaaga aaattccagg gatttcagga attgatacgc gtgctcttac
     3721 caagattatc cgtaagcatg gtactatgcg tgcaaccttg acccatgttg gggacagtat
     3781 ggaccatgtg acggaccagc tccaagcaac agttttaccg acagacaata tcaaacaggt
     3841 ttctactaaa acgtcttatc cagctccagg agttggtttg agcgtggtgc tagtggactt
     3901 tggtctcaag cactcaatcc tacgtgaact ttctaaacgc aactgtaacg tgacagttgt
     3961 tccttattcg acaacggctg aagaaattct ccatctcaat cctgatggag ttatgttgtc
     4021 aaatggtcca ggtaacccag aagacgttcc acaagcactc gacatgattc gcggtgtaca
     4081 aggaaaaatt ccaatctttg gtatttgtat gggacaccaa ctctttgcaa tggcaaacgg
     4141 ggctaagacc tataagatga agtttggcca tcgtggattc aaccatgcgg tacgtgaaat
     4201 cgcaacagga cgagtagact tcaccagcca gaaccatggt tatgcagtca gccgcgagga
     4261 tttgccagag cacttgatta ttacccacga agaaatcaat gacaagtcag tggaaggtgt
     4321 gcgccacaga taccaacctg ctttctctgt tcaataccac ccagatgcag ctcctgggcc
     4381 acacgacgct agctacctat ttgacgagtt tatcgagatg atggaagttt ttaaacaatc
     4441 aaactaagaa cgagtaaaag ctcgtcggag aatttatgta actgaacacg gacggaaagc
     4501 tcagaattta gagaaaccaa cttggattgt caatccttcc ttgatttctt aaaattcaat
     4561 cgctttctat tcgtcctttg tatcttattt aatgtcgccc tgagaggcga cgaatagaaa
     4621 ggagaagata cattgttcgc ggaagtgaac acgccctaag aactgtgtga aaaagataaa
     4681 catcgtcttg acgctgaagg cgtctgcgcc gagtttccta ttttcactgt gttctttacg
     4741 ggctttgtat cataaactat gcctaaacgt actgatattc aaaaaattat ggtgattggt
     4801 tctggtccga ttattattgg tcaggctgct gagtttgact acgctgggac ccaggcttgc
     4861 ttgtcgttga aagaggaagg ttatgaggtt gttttggtta actcaaatcc tgcaaccatc
     4921 atgacggaca aggaaattgc tgacaaggtt tacattgaac cgattacact tgagtttgtg
     4981 acacgtattc ttcgtaagga acgtccagat gccttgctac caacactcgg tggtcagaca
     5041 ggtctcaaca tggccatgga attatctaaa aatggtatcc tagacgagct tggcgttgaa
     5101 cttctgggta ccaaattatc tgccattgac caagcggagg accgtgacct ctttaaacaa
     5161 ttgatggaag agcttgagca acccattcca gaatctgaaa ttgttaacac agtagaagaa
     5221 gcagttgcct ttgcagcgac aattggctac ccagtcatcg ttcgtccagc ctttaccctt
     5281 ggtggtactg gtggtggtat gtgtgccaac gaaaaagaat tgcgtgaaat cactgaaaat
     5341 ggtttgaaat tgtcacctgt tacccaatgt ttgattgagc gttcgattgc cggttttaag
     5401 gaaattgaat acgaagtgat gcgtgactca gctgacaatg ccttggttgt ttgtaacatg
     5461 gaaaactttg acccagttgg gattcacaca ggggattcca ttgtatttgc ccctgcgcaa
     5521 accatgtcag actatgaaaa ccaaatgctt cgtgatgcga gcttgagcat tattcgcgcc
     5581 ctcaagattg aaggtggatg taatgttcag ctagctcttg atcctaacag cttcaagtat
     5641 tatgttatcg aagtaaaccc tcgtgtatca cgttcgtcag cccttgcttc taaagcgaca
     5701 ggatatccga ttgctaagtt ggctgccaag attgcagtag gtttgacctt ggatgaggtt
     5761 ataaacccag ttacaggttc aacctatgcc atgtttgaac cagcccttga ctacgtagtt
     5821 gctaagattc cacgtttccc atttgacaag tttgaaaagg gtgaacgccg tctcggtaca
     5881 caaatgaagg cgactggaga agtcatggca atcggtcgta acatcgagga atctcttctc
     5941 aaggcctgcc gctcccttga aattggggtg caccacaatg aaatacctga acttgcagca
     6001 gtttctgatg atgccttgat tgaaaaggtt gtcaaagccc aagatgaccg tctcttctac
     6061 gtatcagaag ccattcgtcg tggctacaca cctgaagaaa ttgcagagct tacaaaaatt
     6121 gatatcttct atcttgataa actcttgcat atctttgaaa ttgagcaaga attgggtgct
     6181 catccacaag atctagaagt tttgaaaaca gccaaactta atggtttctc agaccgtaag
     6241 attgctgaac tctggggaac gactgatgat caagttcgcc aacttcgctt ggaaaacaag
     6301 attgttccag tttataagat ggtagatact tgtgcggcag agttcgactc tgaaacgcca
     6361 tatttctatt caacctatgg ttgggaaaat gaatctatca gatctgataa agaatctgta
     6421 cttgtcctag gttcaggtcc aatccgtatc ggtcaagggg ttgagtttga ctacgcaacc
     6481 gttcactctg ttaaggctat ccaggcagct ggttatgaag ctatcatcat gaactcaaac
     6541 ccagagaccg tttcaacaga cttctctgta tcagataagc tttactttga gccattgaca
     6601 ttcgaagatg ttatgaacgt cattgacttg gaacaaccaa agggagttat cgttcagttt
     6661 ggtggtcaaa cagccatcaa ccttgcggag ccattggcaa aagcaggtgt gaccatcctt
     6721 ggtacacagg ttgctgacct agaccgtgcc gaagaccgtg acctcttcga gcaagctctc
     6781 aaagaattgg atattccaca gccaccagga caaacggcta ccaatgaaga agaagcagct
     6841 cttgcagctc gtaagattgg cttcccagtt cttgtccgcc catcttatgt acttggtgga
     6901 cgtgccatgg aaatcgttga aaacgaagaa gaccttcgtt cttacatgcg aactgctgtt
     6961 aaggctagtc cagatcaccc agttcttgtc gactcttata tcgttgggca agagtgcgaa
     7021 gttgatgcca tttcagatgg taaagatgtg ctcattcctg gtatcatgga gcatatcgaa
     7081 cgtgctggtg tccactcagg tgactcaatg gctgtttacc caccacaaac cttgtcgcaa
     7141 aaggttcagg agaccatcgc agactacacc aaacgcttag caatcggtct tcactgcctt
     7201 ggaatgatga acatccagtt tgttatcaag gatgaaaaag tctacgttat tgaggtcaat
     7261 ccacgtgcca gccgtactgt tccattccta tctaaggtaa ccaatattcc tatggctcaa
     7321 gtagcgacca agctcattct tggtcaaagt ttatcagaac ttggctacca aaatggactt
     7381 taccctgaaa gcacccgtgt tcatatcaag gcacctgtct tctcctttac caaactagct
     7441 aaggtagaca gcttgctcgg tcctgaaatg aagtcaacag gtgaagttat gggttctgat
     7501 gctactttgg aaaaagctct ctataaagcc tttgaagctt cttatctaca cttgccaact
     7561 tttggtaatg tcgtctttac catcgctgat gatgccaaag aagaagcctt gaacttggct
     7621 cgtcgtttcc aaaacattgg ttatggaatc cttgcgacag aagggacagc agccttcttt
     7681 gctagtcatg gcttgcaagc ccaacctgtt ggtaagattg gtgatgacga taaggatatc
     7741 ccaagttttg tacgcaaagg aagaattcaa gctatcatta acacagtagg aacaaaacga
     7801 actgctgacg aagatggtga gcaaattcgt cgttcagcca ttgaacacgg ggtgcccctc
     7861 ttcacagcgc tagatacagc taatgccatg cttaaggtac ttgaaagtcg tagctttgtt
     7921 acagaagcga tttaaataga aaaataagat
//
LOCUS       DAVKBK010000076         7252 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVKBK010000076 DAVKBK010000000
VERSION     DAVKBK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.076"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(98..2356)
                     /locus_tag="VWX69_001823"
     CDS             complement(98..2356)
                     /locus_tag="VWX69_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9193119.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VWX69_001824"
     CDS             complement(2585..2815)
                     /locus_tag="VWX69_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU9193120.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VWX69_001825"
     CDS             3005..3688
                     /locus_tag="VWX69_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9193121.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VWX69_001826"
     CDS             3688..4422
                     /locus_tag="VWX69_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9193122.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VWX69_001827"
     CDS             4576..5433
                     /locus_tag="VWX69_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU9193123.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5570..6391
                     /locus_tag="VWX69_001828"
     CDS             5570..6391
                     /locus_tag="VWX69_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEU9193124.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            6405..7244
                     /locus_tag="VWX69_001829"
     CDS             6405..7244
                     /locus_tag="VWX69_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU9193125.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKVMK
                     RYV"
BASE COUNT         2073 a         1324 c         1621 g         2234 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata cggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggtccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc caacttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg agggcaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ttaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag cttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gatggaaaat attaccttgt cacctatcaa gactaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatac aatcaggatc cagcttggca tgggattttg
     4861 gttcagttgc cattaccaaa acacattgat gaagaggcgg ttctattggc tattgaccca
     4921 gaaaaggatg tggatggttt ccatcctcta aatatgggac gcctttggtc tggacatcca
     4981 gtcatgattc catcaacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgaa
     5041 ttagaaggta aaaatgcggt tgtcatcggt cgttctaata tcgttggaaa acccatggct
     5101 cagcttcttt tggccaagaa tgcaacagtg actttgaccc actcacgcac ccataatctt
     5161 gctaaggtgg ctgctaaagc agatattctg gtggtcgcaa tcggtcgtgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggta gtcattgacg ttgggatgaa tcgtgatgaa
     5281 aatggtaagc tctgtgggga tgtggattat gaggcagttg ccccacttgc tagctatatt
     5341 acgccagtcc ctggaggtgt cggccctatg accattacta tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaaa atcgctgaag agagtgtatt
     5461 ttctatagct atatttaaaa tggcagaaat gaatattaaa ttttagatat aagattacaa
     5521 aaggaggtct gcgcctcctt tttgttgtat aatggagtga ggtgattaga tgattttaaa
     5581 aatttataat agggaatata gtttacaatg ggatggaata tactacctag cactaattga
     5641 ttatccaaat attcaagagt gggaattaga aaaaattgct aaatttatag cttacgaaaa
     5701 acttcataaa cgtcaaacaa gtattgagtg tgctgattct tgtttaaaaa aagaaatttt
     5761 agattacatc tgtcagcatc cctttctgcc accatttacc cctacagata aaagagtagc
     5821 ctcgacttat gatctacata agaggttagt gacttcagac tactgtagtc atactacgac
     5881 tatagatgca gcgatttcta tctttaaaac aggtcagctc ttatctgctg tgaaagcctt
     5941 taggcgagat gctgaagagt tggttttgga tagtagaaat gctgcatcgg atccgataga
     6001 ttattttgat tatgtcatgt tagggtggtc aaatacaagt tctggttatc gattagcgat
     6061 ggagcgttta ttaggtcgag ctccttcaga gaaagaatta caagacaagt ttattcctgg
     6121 agtgagtttt cattttatct atacagattt gattaaagtt actggttata tttttgatgg
     6181 ctaccatgtt gcaaaaatta aggacatgtt gaatttattt agtgagttgt atatttgtat
     6241 tattccaact cataataaga gccaatttga aaatattatt ccaactaaaa tacaagatag
     6301 ggtgcattat cttgactatg ctggagaaga cttagaagag tggactaaga aagtctatca
     6361 agttgtttta aaacaatcag ataaaggata gttgaggaag aacgatgaaa gtgattgatc
     6421 aagccttact agaaaaagtt attattgaac gttctcgtac tagtcataaa ggagactatg
     6481 gccgtctgct gtttcttggt ggaacttatc cttatggtgg tgccatcatc atggctgctt
     6541 tggcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacagatagg gaaaatattc
     6601 cagccctgca cagccattta cctgaggcta tggccttttc tcttcaagac cagcagttgt
     6661 taaaagagca attggagaag gcagaagttg tcttgctggg gccgggttta cgagacgatg
     6721 cttttggaga agatctagtt aaacaggtct ttgctggctt aagacaaaat cagattttga
     6781 ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt tcctcaagcc
     6841 agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt acgattgaaa
     6901 agcaaaagga agatgcaacg gctagtgccc taacttcctt ccctcaagga acaattttgg
     6961 tggagaaagg ttcagctact cgtatttggc aagctggcca atcagattat taccagttac
     7021 aggttggcgg tccctatcag gcgactgggg gaatgggaga tacgcttgct gggatgattg
     7081 caggatttgc aggccagttt aagcaagcta gtctttacga acgtgtggca gtagcgaccc
     7141 atcttcattc agccatagcc caagaactag ctcaagaaca gtatgtggtt ttgccaacgg
     7201 agattagtaa ttgtcttcct aaagtaatga aaagatatgt ctaaaatagt ta
//
LOCUS       DAVKBK010000077         6936 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVKBK010000077 DAVKBK010000000
VERSION     DAVKBK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6936
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.077"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(93..356)
                     /locus_tag="VWX69_001830"
                     /pseudo
     CDS             complement(93..356)
                     /locus_tag="VWX69_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            554..2320
                     /gene="patB"
                     /locus_tag="VWX69_001831"
     CDS             554..2320
                     /gene="patB"
                     /locus_tag="VWX69_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU9193126.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2459..3148
                     /locus_tag="VWX69_001832"
     CDS             2459..3148
                     /locus_tag="VWX69_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9193127.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            3152..3331
                     /locus_tag="VWX69_001833"
     CDS             3152..3331
                     /locus_tag="VWX69_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193128.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3318..4667
                     /locus_tag="VWX69_001834"
     CDS             3318..4667
                     /locus_tag="VWX69_001834"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU9193129.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4791..6251
                     /locus_tag="VWX69_001835"
     CDS             4791..6251
                     /locus_tag="VWX69_001835"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU9193130.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            6265..6696
                     /locus_tag="VWX69_001836"
     CDS             6265..6696
                     /locus_tag="VWX69_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9193131.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
     gene            6820..6891
                     /locus_tag="VWX69_001837"
     tRNA            6820..6891
                     /locus_tag="VWX69_001837"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6853..6855,aa:Glu,seq:ttc)
BASE COUNT         2180 a         1324 c         1495 g         1937 t
ORIGIN      
        1 ttgtaatgtt ttccttgttc taacttagtc ttaagatagg ccttaaaagc aggtgaaaag
       61 cgagggcatg ctttggcagc ttgtatgagt acctaccgca gatgagggga accccgtttg
      121 accattcttt ctgctaaatc aatctgacct gactgataaa tagaagaatc cagtccagcg
      181 aaagcttgta attgagcagg attatcaaag gcatgaatat ttcgaatctc ggctaaaatg
      241 accgccccta aacgaccccc aatcccagta accgtcgtga tgaccgagtt gaactcagcc
      301 atcaagtcat tgacacattt tttcgccttg tcaatgagcc tcttgtaatg tttgatgttt
      361 tcattacaag agataaaacg tttatgcgtt atcaaactca ttaccaattg aaacaaaaag
      421 ctgtggttag atcctttcgg aaattgtcaa gcgattggag gaaatgaact aatccacagc
      481 ggcttattcc aagtatacca cttgggcttt ggcagtagtt aactgcgcta aatataatat
      541 aaggaggagt aaaatgaaga cagttcaatt tttttggcat tattttaagg tctacaagtt
      601 ctcatttgta gttgtcatcc tgatgattgt tctggcgact tttgcccaag ccctctttcc
      661 agtcttttct ggacaagcgg tgacgcagct agccaattta gttcaagctt atcaaaatgg
      721 caatccagaa cttgtatggc aaagcctatc aggaatcatg gtcaatcttg gcctgctggt
      781 tttggttcta tttatctcta gtgtaatata catgtgtctc atgacgcgcg tgattgcaga
      841 atcgaccaac gagatgcgca aaggcctctt tggtaagctt gctcagttga cggtttcttt
      901 ctttgaccgt cgacaagatg gcgatatcct gtctcatttt accagtgatt tggataatat
      961 cctccaagcc tttaacgaaa gcttgattca ggtcatgagc aatattgttt tatacattgg
     1021 tctgattctt gtcatgtttt cgagaaatgt gacgctggct ctcatcacca ttgccagcac
     1081 tccattggct ttccttatgc tgattttcat cgtgaaaatg gcacgtaaat acaccaacct
     1141 ccagcagaaa gaggtaggga agctcaacgc ctatatggat gagagcatct caggccaaaa
     1201 agccgtgatt gtgcaaggaa ttcaagagga tatgatggca ggatttcttg aacaaaatga
     1261 gcgcgtgcgc aaggcaacct ttaaaggaag aatgttctca ggaattcttt tccctgtcat
     1321 gaatgggatg agcctgatta atacagccat cgtcatcttt gctggttcgg ctgtactttt
     1381 gaatgataag tctattgaaa caagtacagc cctaggtttg attgttatgt ttgcacaatt
     1441 ttcacagcag tactaccagc ctattatcca agttgcagcg agttggggaa gccttcagtt
     1501 ggcctttact ggagctgaac gaattcagga aatgtttgat gcagaggagg aaatccgacc
     1561 tgaaaaggct ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc atatcgattt
     1621 ttcatacttg cctgataaac ctattttgaa agatgtcagc atttctgccc ctaaaggcca
     1681 gatgacagca gttgttgggc ctacaggttc aggaaaaacg actattatga acctcatcaa
     1741 tcgcttttat gatgttgatg ctggtggtat ttattttgat ggtaaagaca ttcgtggcta
     1801 tgacttagat agtcttagaa gcaaggtggg aattgtattg caagattcgg tcttgtttag
     1861 cggaacgatt cgagacaata tccgatttgg tgtgccagat gctaatcagg aaatggttga
     1921 ggtagcagca aaagcaaccc acattcacga ctatatcgaa agtttgcctg ataagtacga
     1981 tactcttatt gatgatgacc agagcatctt ttcaacaggg cagaagcaat tgatttcaat
     2041 cgctcgaacc ctgatgacag atccagaagt tctcattctc gatgaagcaa cttcaaacgt
     2101 agatacggtg acggaaagca agattcagca tgccatggag gtggttgtag caggtagaac
     2161 tagtttcgtc attgcccacc gcttgaaaac cattctcaat gcagatcaga ttattgtcct
     2221 taaagatgga gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc taggtggctt
     2281 ttattcagaa ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg
     2341 ggcagctttt tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa catattagac
     2401 gaaagtcatt ttgagtgata tgataggact atcgttagta ttcgaaagga gaggcatcat
     2461 ggctagaacg gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag aaggcaaaat
     2521 cattcattca tctgtatctt gtagattcgc agagatcatt cgtcaagtcg gtggtctccc
     2581 tttagtcatt cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa
     2641 actcattttg acaggaggcc aaaatgttca tcctcagttt tatggagaga aaaagaccgt
     2701 cgaaagcgat gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc
     2761 gcttcgtcag aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc
     2821 ctttggtgga accctcaatc aagaaatcga aggtcactgg caaggactac ctttcgggac
     2881 atctcactct attgaaacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag
     2941 tcaggtcaac tcagtccatc gtcaaagcat taaagatttg gcacctaatt tccgtgtaac
     3001 tgctattgat tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat
     3061 tatcggttta cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt
     3121 atttgagtat ttattgaatg aactgtaacg attggaacat ctggtcgttc tttcttttat
     3181 tttttcaaaa tttttagaat gtggcatttt acgcaaacgt ttgaattctg ataaaaattg
     3241 gagaaattcg acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga
     3301 aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat
     3361 ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga
     3421 tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat
     3481 acgaccgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg
     3541 atgttttggt tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact
     3601 tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagct ccacaaatcc
     3661 tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag
     3721 acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg
     3781 ctttccgtgt ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa gctaacaaac
     3841 gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaacg
     3901 gttggggaac atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg
     3961 ttggtttgct tccaatcgca gcatcaggag ctgacatcaa agctcttatg gaaggtgcga
     4021 atgcagctcg caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg
     4081 cagtcgttcg taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg
     4141 agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa
     4201 aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg cactcacttg
     4261 gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac
     4321 ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc
     4381 aaggaaaaga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca
     4441 cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg
     4501 gttacactat ctacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca
     4561 acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa
     4621 aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag
     4681 tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt
     4741 gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaact atgtcaaaag
     4801 atatccgcgt acgttacgca ccaagtccaa caggactact acacatcgga aatgcccgta
     4861 cagcattgtt taactacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg
     4921 aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc
     4981 gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg
     5041 agcgtttgga cttgtatcaa aaatacattg accaactatt agctgaagga aaagcctata
     5101 aatcttacgt tacagaagaa gagttggcag ctgaacgtga acgtcaagaa gtagctggcg
     5161 aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcggcttata
     5221 tcgcagaacg tgaagcagct ggtatcatac caacagttcg tttggctgtc aatgagtcag
     5281 gtatctacaa gtggcatgat atggtcaaag gtgatatcga atttgaaggt ggcaatatcg
     5341 gcggtgactg ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgtta
     5401 tcgatgacca cgatatgcaa atctctcatg ttatccgtgg agatgaccat attgctaata
     5461 caccaaaaca gcttatggtc tatgaagctc ttggttggga agctccagag tttggtcaca
     5521 tgaccttgat tatcaactct gagactggta agaagttatc taaacgtgat actaatacac
     5581 ttcaatttat cgaagattac cgaaagaaag gttaccttcc agaagcagtc tttaacttta
     5641 ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca
     5701 ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaat
     5761 tagactggat gagcaatgat tatatcaaga atgcagacct tgaaaccatc tttgaaatgg
     5821 caaaaccatt cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa ttagttgagc
     5881 tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct
     5941 cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa
     6001 cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgatgaa tttgtgacag
     6061 aaaatatctt cccacaaatt aaagcagtcc aaaaagaaac aggtattaaa gggaaaaatc
     6121 ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata
     6181 caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatt ctaaaagaaa
     6241 tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag
     6301 aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca
     6361 gtagaagcag gagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt
     6421 ttccatctct gcgcagaacg ggcgaccctc ttcaatatgt accaattttc aggacaaact
     6481 aaggttaaga aagtattagc ctttcgagac aaaccacctt atggtggaag ttcagccatg
     6541 ccttgcggtg cttgtagaga attcctttta gagcttaatg ctgaaaataa agatgcagaa
     6601 ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg
     6661 tggggagaag aacgtgcttc taagtttaat gagtgataga agagtcagta taattctggc
     6721 tctttttact ataagttgaa aaaataaaaa aaattagaaa aagtagttga caaaatttga
     6781 aaagactgta taatagtaag agttgaaaat aacaactcag gtccgttggt caaggggtta
     6841 agacaccgcc ttttcacggc ggtaacacgg gttcgaatcc cgtacggact atggtatgtt
     6901 gcgtcaggag cacttgatga aaaaaagttt aaaaaa
//
LOCUS       DAVKBK010000078         6824 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVKBK010000078 DAVKBK010000000
VERSION     DAVKBK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6824
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.078"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..379
                     /locus_tag="VWX69_001838"
     CDS             <1..379
                     /locus_tag="VWX69_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9193132.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEEMMTSDFFEAWFQK
                     FLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKK
                     HLKKVLPSCNTFYEALLSCSCFN"
     gene            465..1415
                     /locus_tag="VWX69_001839"
     CDS             465..1415
                     /locus_tag="VWX69_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9193133.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1592..2599
                     /gene="gap"
                     /locus_tag="VWX69_001840"
     CDS             1592..2599
                     /gene="gap"
                     /locus_tag="VWX69_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU9193134.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2667..3503)
                     /locus_tag="VWX69_001841"
     CDS             complement(2667..3503)
                     /locus_tag="VWX69_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9193135.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVRWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGKYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3629..5824
                     /locus_tag="VWX69_001842"
     CDS             3629..5824
                     /locus_tag="VWX69_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9193136.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYNSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5877..6029
                     /gene="rpmG"
                     /locus_tag="VWX69_001843"
     CDS             5877..6029
                     /gene="rpmG"
                     /locus_tag="VWX69_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9193137.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6039..6215
                     /gene="secE"
                     /locus_tag="VWX69_001844"
     CDS             6039..6215
                     /gene="secE"
                     /locus_tag="VWX69_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU9193138.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6270..6806
                     /gene="nusG"
                     /locus_tag="VWX69_001845"
     CDS             6270..6806
                     /gene="nusG"
                     /locus_tag="VWX69_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU9193139.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2124 a         1190 c         1480 g         2030 t
ORIGIN      
        1 aagaggtaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
       61 tggtgagtta atcgctccaa tgacttacga agagatgatg acgagcgact tttttgaagc
      121 ttggtttcag aagtttctct taccaacatt aaccacacca tcggttatta ttatggataa
      181 tgcaagattc catagaatgg gtaagttaga acttttatgc gaggagtttg ggcataaact
      241 tttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
      301 caaaaagcac ctcaaaaagg tattaccaag ttgcaatacc ttttatgagg ctcttttgtc
      361 ctgctcttgt ttcaattgac tatagttcac ggatacagtt gggaaagaag ctattaaata
      421 tttggagagt ccttttggga tgaacatgtc aaatattact atagatgggc aagaaaagat
      481 gggcaagaaa tggatctgag tcaaacgatg cttcttatgc tcaagtagtg agtctttatg
      541 atgatacaag tatctctgtt agtaataatg agacggacaa agtgttgact ggatccctct
      601 atactgaaac aaatgaacag ggattaacga ttccaagcag tttactaaaa aattggaatg
      661 aacagacagg aaaaaatttg acaactaatg atcttattgg caaatcagtc tcagccagca
      721 ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt tcaaacgaag attgtacgtg
      781 taatcaatga tgaagatgac atggaggaca gcaacagttt catgctgtct catcaaatgg
      841 aaacgatttt gaaagaggct ggatttacga aagctgtatc ttattttatc ttggaactca
      901 aagatccatc acagacaaaa gtagtaacag aagaattaca gaaaaataag aagtatactg
      961 tgctttctca acagagagtt cttgatattg tgattacctt tattcgtgtt attcagggat
     1021 tattgattgt gctttcatca caagctattg tggtagcagc ggttatgatt ggtatcatta
     1081 tttacatcaa tatcatgcaa cgttccaagg aaataggtgt catgaaagca gttggttatc
     1141 agaatcgtgg tgtcaaagga atttttattt acgaggctat ctggattgta ggcatcgcct
     1201 tgctgctggc atttttggtt gcacaagggg tgggaagttt ggcgaatgcg attgtaagtc
     1261 acttttaccc atccatcact aaggtttttg aattaaatct tttatctgtt ttaggaactc
     1321 tagttttcgc tctattactt ggttatgtct cagcctactt cccggcgcgt aagattagta
     1381 aaatggatcc tgtagaatcg ttacgctatg aataataagg gattccttga tttacagtct
     1441 taaaaagaaa ctcacataga aaaacaatgg ccatacttgc aattcaactc aaatagttgt
     1501 ataataggtt tgttgaaagg tgatttgtag tgattcaagt tactcttttc acaataaaaa
     1561 tttcatgatt ttcataagga ggaaatcact aatggtagtt aaagttggta ttaacggttt
     1621 cggacgtatc ggtcgtcttg ctttccgtcg tatccaaaac gtagaaggtg ttgaagttac
     1681 acgcatcaac gaccttacag atccagttat gcttgcacac ttgttgaaat acgacacaac
     1741 tcaaggtcgt ttcgacggta ctgttgaagt taaagaaggt ggattcgaag ttaacggtaa
     1801 attcgttaaa gtttctgctg aacgtgatcc agagcaaatc gactgggcta ctgacggtgt
     1861 agaaatcgtt cttgaagcta ctggtttctt tgctaagaaa gaagcagctg aaaaacacct
     1921 taaaggtgga gctaaaaaag ttgttatcac tgctcctggt ggaaacgacg ttaaaacagt
     1981 tgtattcaac actaaccacg acgttcttga cggtactgaa acagttatct caggtgcttc
     2041 atgtactaca aactgcttgg ctccaatggc taaagctctt caagataact ttggtgttgt
     2101 tgaaggattg atgactacta tccacgctta cactggtgac caaatgatcc ttgacggacc
     2161 acaccgtggt ggtgaccttc gccgtgctcg cgctggtgct gcaaacatcg ttcctaactc
     2221 aactggtgct gcaaaagcta tcggtcttgt aatcccagaa ttgaatggta aacttgatgg
     2281 atctgcacaa cgcgttccaa ctccaactgg atcagttact gaattggtag cagttcttga
     2341 aaagaacgtt actgttgatg aagtgaacgc agctatgaaa gcagcttcaa acgaatcata
     2401 cggttacaca gaagatccaa tcgtatcttc agatatcgta ggtatgtctt acggttcatt
     2461 gtttgacgca actcaaacta aagttcttga cgttgacggt aaacaattgg ttaaagttgt
     2521 atcatggtac gacaacgaaa tgtcatacac tgcacaactt gttcgtactc ttgaatactt
     2581 cgcaaagatt gctaaataat tcttgagttg atagaaagca aggctttgtg gtcttgcttt
     2641 tttatatgga aaaatggatg acacgatcat ccattctttt ttaattcttt ttcaaatgta
     2701 tttgaaaggg tagtgaaagt tagcctctct aaagtaagtg ggtgggtaaa ggaaagtcgg
     2761 aaggcatgaa gcataagccg gcttgtcttt gatttactat tatagagagg gtctcccagg
     2821 ataggaagat tatgatgcaa aaggtgcaca cgaatctgat gggttcgccc tgtctttagc
     2881 ttgcaatgag ccaaggaagt cttgtttgag aattgcttta atctgcttac atgcgtttca
     2941 gcatatttcc cattttttgc atcaactatt ctttttctac gatcatggcg atcacgtcca
     3001 attttgtctc tgaaaacaag ttcttttctg ttgatatttc catcaactag agcccaatat
     3061 tctctagaaa tctctttttt ctccaataag cgattgagaa tgggcaggat aaaaggattt
     3121 ttggcaaaga gaactaagcc actggtttcc atgtccagac gatgaacgac atagcaggtt
     3181 tggccaacat aggtactgac atggttaaga agggcaattt cgtttggttg attaccatgc
     3241 gttttcatcc cctctggttt gtttacaata atcaagtgtt gatcttgata aacttcctgc
     3301 actaagtctg ggttgcccca agggatcgtc ttttggggat aatcttcctc gtcaaaagtc
     3361 aactggcaaa catctccagg atttacgatt tcgttccagc ggacttcttc ttgatttatc
     3421 aaaatatgtt tcttgattct caaaaaatga cggatttttc tagggatgag gagttgttcc
     3481 tcaagtaatt gctttaccgt catttgaggt agagaggcgg gtaatgtaaa tgtgaattgc
     3541 atacagatat tgtaacaaaa aaagccctat ttggatagga aatagctaaa ttcttgtctt
     3601 cctatgatga agatgataaa ataaacgcat gaaattagat aaattatttg agaaatttct
     3661 ttctcttttt aaaaaagaaa caagtgaact agaggactct gattctacta tcttacgtcg
     3721 ctctcgtagt gatcgaaaaa aattagccca agtaggtccg attcgaaaat tctggcgtcg
     3781 ttatcatcta acaaagatta tccttatact aggtttgagt gcaggcttgc tagttggaat
     3841 ctatttgttt gctgtagcca agtcgaccaa tgtcaatgat ttgcaaaatg ccttgaaaac
     3901 tcggactctt atttttgacc gtgaagaaaa agaggctggt gccttgtctg gtcaaaaggg
     3961 aacctatgtt gagctgactg acatcagtaa aaacttgcag aatgctgtta ttgcgacaga
     4021 agaccgttct ttctataaaa atgacgggat taactatggc cgtttcttct tggctattgt
     4081 cactgctgga cgttcaggtg gtggctctac cattacccaa cagctggcta aaaacgccta
     4141 tttatcgcag gatcaaactg ttgagagaaa agcgaaagaa tttttccttg ccttagaatt
     4201 aagcaaaaaa tatagtaagg agcaaattct aaccatgtac cttaacaacg cttattttgg
     4261 aaatggtgtg tggggtgtag aagatgcgag taagaaatac tttggagttt ctgcatcaga
     4321 agtgagtctg gatcaagctg cgactctggc agggatgctc aaggggccgg aactgtataa
     4381 tcccttgaat tccgtagaag attctactaa tcggcgcgat actgtcttga agaatatggt
     4441 tgcagcagga tatattgata aaaaccaaga aaccgaagct gctgaagttg atatgacttc
     4501 gcaattgcac gataagtatg aaggaaaaat ctcagattac cgttacccct cttattttga
     4561 tgcggtggtt aatgaagctg tttccaagta taatctaaca gaggaagaga ttgtcaataa
     4621 tggctaccgc atttacacag agctggacca aaactaccaa gcaaatatgc agattgttta
     4681 tgaaaacaca tcgctatttc cgagggcaga ggatggaacg tttgctcaat caggaagtgt
     4741 agctctcgaa ccgaaaacag ggggagttcg tggagttgtc ggtcaagttg ctgacaatga
     4801 taaaactgga ttccggaatt tcaactatgc aacccaatca aagcgtagtc ctggttctac
     4861 aattaagcct ttagttgttt atacgccagc agttgaagca ggctgggctt tgaataagca
     4921 gttggataac cataccatgc agtataacag ctataaggtt gataactatg cagggatcaa
     4981 aacgagtcga gaagttccta tgtatcaagc cttggcagaa tcgcttaatc tacctgctgt
     5041 tgccactgtt aatgatttgg gtgttgacaa ggcttttgag gcaggcgaaa aattcggact
     5101 caacatggaa aaggtcgacc gtgttcttgg tgtcgccttg ggaagcggtg ttgaaaccaa
     5161 ccctcttcaa atggctcaag catacgctgc ctttgcaaat gaaggtttaa tgcctgaagc
     5221 tcattttatt agtagaattg aaaatgctag tggacaagtt attgcgagtc ataaaaattc
     5281 acaaaaacgg gtgattgata agtctgtagc tgacaagatg accagtatga tgttggggac
     5341 tttcaccaac ggtaccggta ttagttcatc gcctgcagac tatattatgg cagggaaaac
     5401 tggaacaact gaagcagttt tcaatccgga gtacacaagt gaccagtggg taattggtta
     5461 tactccggat gtagtgatta gccactggct tggctttcct accactgatg aaaatcacta
     5521 tctagctggc tctacttcaa acggtgcagc tcatgtcttt agaaacattg ccaataccat
     5581 tttaccttat acgccaggaa gtacctttac ggttgaaaat gcttataagc aaaatggaat
     5641 tgcaccagcc aatacaaaaa gacaagtaca aaccaatgat aatagccaga cagatgataa
     5701 tttgtctgat attcgagggc gtgcgcaaag tctagtagat gaggctagcc gggctatctc
     5761 agatgcgaag attaaggaaa aggctcaaac aatatgggat tcgatagtca atctatttcg
     5821 ttaagatgct tgtcaaagcc tagctttctt gttataatgg ataagatgga ggcgttatgg
     5881 cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc gagaaactat tcaatcaaga
     5941 tcagcggaaa ccccaagcct acacgactag aagtaaataa attttgtaag cattgtggca
     6001 agtacactac acacagagaa acgagatagg agagagcgat gcgttttatt ggagatattt
     6061 ttagacttct taaagacaca acatggccaa ctcgcaagga aagctggaga gattttcgtt
     6121 ctatcatgga atacacagct ttctttgtag taattattta catttttgac cagttgattg
     6181 tttcaggttt gattcgattt attaacattt tttagaagat tagtggagtt aattacacta
     6241 gaaatcttct atttatgaaa ggaaatatca tggatagttt tgataaagga tggtttgttt
     6301 tacaaactta ttctggttat gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa
     6361 cctacaatat gttggataat attctacgcg ttgaaattcc aacacaaaca gtgcaagttg
     6421 aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt tccaggttat gttcttgtag
     6481 aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat gttacaggat
     6541 ttgtcggatc acacgggaac agatcaaaac caactccatt attggaacaa gaaattcgtg
     6601 acattttggt atctatggga caaactgttc aagaatttga tttcgatgtt gagattggtc
     6661 aaactgtacg tattattgat ggtgcttttg cagactacac tggtaagatt acagaaattg
     6721 ataataacaa agtgaaaatg attatctcta tgtttggtaa tgacacagtt gcagaagtaa
     6781 acctaaacca aatcgcagaa ttataaccct gagagaggct ggag
//
LOCUS       DAVKBK010000079         5849 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVKBK010000079 DAVKBK010000000
VERSION     DAVKBK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5849
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.079"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            82..561
                     /locus_tag="VWX69_001846"
     CDS             82..561
                     /locus_tag="VWX69_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU9193140.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            656..727
                     /locus_tag="VWX69_001847"
     tRNA            656..727
                     /locus_tag="VWX69_001847"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:689..691,aa:Glu,seq:ttc)
     gene            979..2524
                     /locus_tag="VWX69_001848"
     rRNA            979..2524
                     /locus_tag="VWX69_001848"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2576..2648
                     /locus_tag="VWX69_001849"
     tRNA            2576..2648
                     /locus_tag="VWX69_001849"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2609..2611,aa:Ala,seq:tgc)
     gene            2773..5674
                     /locus_tag="VWX69_001850"
     rRNA            2773..5674
                     /locus_tag="VWX69_001850"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5751..>5849
                     /gene="rrf"
                     /locus_tag="VWX69_001851"
     rRNA            5751..>5849
                     /gene="rrf"
                     /locus_tag="VWX69_001851"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1729 a         1131 c         1670 g         1319 t
ORIGIN      
        1 ggagctaaag ggaacagaat ggagaaaatg gaacaaatgt gttttctaat ctgttagact
       61 gtatctagaa aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgtg
      121 tataagtgta gaaatgaata ttaccttcat ttatgggaat tatcggattg ggaccaagaa
      181 ggcatgctct gcttacatga attgattagt agagaagaag gactggtaga cgatattcca
      241 cgtttaagga aatatttcaa aaccaagttt cgaaatcgaa ttttagacta tatccgtaag
      301 caggaaagtc agaagcgtag atacgataaa gaaccctatg aagaagtggg tgagatcagt
      361 catcgtataa gtgagggggg tctctggcta gatgattatt atctctttca tgaaacacta
      421 agagattata gaaacaaaca aagtaaagag aaacaagaag aactagaacg cgtcttaagc
      481 aatgaacgat ttcgagggcg tcaaagagta ttaagagact tacgcattgt gtttaaggag
      541 tttactatcc gtacccacta gtaagtcatg caaaaaaaaa tgaaaaaaat tagaaaaagt
      601 agttgacaaa gtttgaaaag actgtataat agtaagagtt gaaaataaca actcaggtcc
      661 gttggtcaag gggttaagac accgcctttt cacggcggta acacgggttc gaatcccgta
      721 cggactatgg tatgttgcgt caggagcact tgatgaaaaa aagtttaaaa aaacttaaaa
      781 atcttcaaaa aagtgttgac aagtgaaagt ggctgtgata tactaatata gttgtcgctt
      841 gagagaagca agtgacaaag acctttgaaa actgaacaag acgaaccaat gtgcagggcg
      901 ctacaacata agttgtagta ctgaacaatg aaaaaacaat aaatctgtca gtgacagaaa
      961 tgagtaagaa ctcaaacttt taatgagagt ttgatcctgg ctcaggacga acgctggcgg
     1021 cgtgcctaat acatgcaagt agaacgctga aggaggagct tgcttctctg gatgagttgc
     1081 gaacgggtga gtaacgcgta ggtaacctgc ctggtagcgg gggataacta ttggaaacga
     1141 tagctaatac cgcataagag tagatgttgc atgacatttg cttaaaaggt gcacttgcat
     1201 cactaccaga tggacctgcg ttgtattagc tagttggtgg ggtaagggct caccaaggcg
     1261 acgatacata gccgacctga gagggtgatc ggccacactg ggactgagac acggcccaga
     1321 ctcctacggg aggcagcagt agggaatctt cggcaatgga cggaagtctg accgagcaac
     1381 gccgcgtgag tgaagaaggt tttcggatcg taaagctctg ttgtaagaga agaacgagtg
     1441 tgagagtgga aagttcacac tgtgacggta tcttaccaga aagggacggc taactacgtg
     1501 ccagcagccg cggtaatacg taggtcccga gcgttgtccg gatttattgg gcgtaaagcg
     1561 agcgcaggcg gttagataag tctgaagtta aaggctgtgg cttaaccata gtaggctttg
     1621 gaaactgttt aacttgagtg caagagggga gagtggaatt ccatgtgtag cggtgaaatg
     1681 cgtagatata tggaggaaca ccggtggcga aagcggctct ctggcttgta actgacgctg
     1741 aggctcgaaa gcgtggggag caaacaggat tagataccct ggtagtccac gctgtaaacg
     1801 atgagtgcta ggtgttagac cctttccggg gtttagtgcc gtagctaacg cattaagcac
     1861 tccgcctggg gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca
     1921 agcggtggag catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat
     1981 ccctctgacc gctctagaga tagagttttc cttcgggaca gaggtgacag gtggtgcatg
     2041 gttgtcgtca gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta
     2101 ttgttagttg ccatcattta gttgggcact ctagcgagac tgccggtaat aaaccggagg
     2161 aaggtgggga tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca
     2221 atggctggta caacgagtcg caagccggtg acggcaagct aatctcttaa agccagtctc
     2281 agttcggatt gtaggctgca actcgcctac atgaagtcgg aatcgctagt aatcgcggat
     2341 cagcacgccg cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccacgaga
     2401 gtttgtaaca cccgaagtcg gtgaggtaac cgtaaggagc cagccgccta aggtgggata
     2461 gatgattggg gtgaagtcgt aacaaggtag ccgtatcgga aggtgcggct ggatcacctc
     2521 ctttctaagg ataaggaact gcgcattggt cttgtttagt cttgagaggt cttgtggggc
     2581 cttagctcag ctgggagagc gcctgctttg cacgcaggag gtcagcggtt cgatcccgct
     2641 aggctccatt ggtgagagat caccaagtaa tgcacattga aaattgaata tctatatcaa
     2701 atagtaacaa gaaaataaac cgaaaacgct gtagtattaa taagagttta tgactgaaag
     2761 gtcagaaaat aaggttaagt taataagggc gcacggtgga tgccttggca ctaggagccg
     2821 acgaaggacg tgacaaacga cgatatgcct tgggtagctg taagtaagcg atgatccagg
     2881 gatttccgaa tgggggaacc caacaggtaa tacctgttac ctacatctgt taaggatgtg
     2941 aggaggaaga cgcagtgaac tgaaacatct aagtagctgc aggaagagaa agcaaaagcg
     3001 attgccttag tagcggcgag cgaaacggca gaagggcaaa ccgaagagtt tactcttcgg
     3061 ggttgtagga ctgcaatgtg gactcaaaga ttatagaaga atgatttggg aagatcagcc
     3121 aaagagagta atagcctcgt atttaaaata gtctttgtac ttagcagtat cctgagtacg
     3181 gcgggacacg tgaaatcccg tcggaatctg ggaggaccat ctcccaaccc taaatactcc
     3241 ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg aaaagcaccc cgggagggga
     3301 gtgaaataga acctgaaacc gtgtgcctac aacaagttcg agcccgttaa tgggtgagag
     3361 cgtgcctttt gtagaatgaa ccggcgagtt acgttatgat gcgaggttaa gttgaagaga
     3421 cggagccgta gggaaaccga gtctgaatag ggcgccttag tatcatgacg tagacccgaa
     3481 accatgtgac ctacccatga gcaggttgaa ggtgcggtaa gacgcactgg aggaccgaac
     3541 cagggcacgt tgaaaagtgc ttggatgact tgtgggtagc ggagaaattc caaacgaact
     3601 tggagatagc tggttctctc cgaaatagct ttagggctag cgtcgacatt agagattctt
     3661 ggaggtagag cactgtttgg gtgaggggtc catcccggat taccaatctc agataaactc
     3721 cgaatgccaa tgaattatgg tcggcagtca gactgcgagt gctaagatcc gtagtcgaaa
     3781 gggaaacagc ccagaccacc agctaaggtc ccaaaataat tgttaagtgg aaaaggatgt
     3841 ggggttgcac agacaactag gatgttagct tagaagcagc tattcattca aagagtgcgt
     3901 aatagctcac tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa acaatttacc
     3961 gaagctgtgg atacctttat aggtatggta ggagagcgtt ctatgtgtga tgaaggtata
     4021 ccgtgaggag tgctggaacg catagaagtg agaatgccgg tatgagtagc gaaagacagg
     4081 tgagaatcct gtccaccgta agactaaggt ttccagggga aggctcgtcc gccctgggtt
     4141 agtcgggacc taaggagaga ccgaaaggtg tatccgatgg acaacaggtt gatattcctg
     4201 tactagagta tgtagtgatg gagggacgca gtaggctaac taaagcagac gattggaaga
     4261 gtctgtctaa gcagtgaggt gtgaattgag tcaaatgctt aattctataa cattgagctg
     4321 tgatggggag cgaagtttag tagcgaagtt agtgacgtca cactgccaag aaaagcttct
     4381 agcgtttaaa catactctac ccgtaccgca aaccgacaca ggtagtcgag gcgagtagcc
     4441 tcaggtgagc gagagaactc tcgttaagga actcggcaaa atgaccccgt aacttcggga
     4501 gaaggggtgc tgacttaaag tcagccgcag tgaataggcc caagcaactg tttatcaaaa
     4561 acacagctct ctgctaaatc gtaagatgat gtataggggg tgacgcctgc ccggtgctgg
     4621 aaggttaaga ggagtgctta gcgtaagcga aggtatgaat tgaagcccca gtaaacggcg
     4681 gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt ccgacccgca
     4741 cgaaaggcgt aatgatttgg gcactgtctc aacgagagac tcggtgaaat tttagtacct
     4801 gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt actgcagttt
     4861 gatattgagt gtctgtacca catgtacagg ataggtagga gtctaagaga tcgggacgcc
     4921 agtttcgaag gagacgctgt tgggatacta cccttgtgtt atggccactc taacccagat
     4981 aggtgatccc tatcggagac agtgtctgac gggcagtttg actggggcgg tcgcctccta
     5041 aaaggtaacg gaggcgccca aaggttccct cagaatggtt ggaaatcatt cgcagagtgt
     5101 aaaggtataa gggagcttga ctgcgagagc tacaactcga gcagggacga aagtcgggct
     5161 tagtgatccg gtggttccgt atggaagggc catcgctcaa cggataaaag ctaccctggg
     5221 gataacaggc ttatctcccc caagagttca catcgacggg gaggtttggc acctcgatgt
     5281 cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc gcccattaaa
     5341 gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc cgtcgcgggc
     5401 gtaggaaatt tgagaggatc tgctcctagt acgagaggac cagagtggac ttaccgctgg
     5461 tgtaccagtt gtcttgccaa aggcatcgct gggtagctat gtagggaagg gataaacgct
     5521 gaaagcatct aagtgtgaaa cccacctcaa gatgagattt cccatgatta tatatcagta
     5581 agagccctga gagatgatca ggtagatagg ttagaagtgg aagtgtggcg acacatgtag
     5641 cggactaata ctaatagctc gaggacttat ccaaagtaac tgagaatatg aaagcgaacg
     5701 gttttcttaa gttgaataga tattcaattt tgagtaggta ttactcagag ttaagtgacg
     5761 atagcctagg agatacacct gtacccatgc cgaacacaga agttaagccc tagaacgccg
     5821 gaagtagttg ggggttgccc cctgtgaga
//
LOCUS       DAVKBK010000080         5665 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVKBK010000080 DAVKBK010000000
VERSION     DAVKBK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5665
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.080"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            90..278
                     /locus_tag="VWX69_001852"
     CDS             90..278
                     /locus_tag="VWX69_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU9193141.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            340..1098
                     /locus_tag="VWX69_001853"
     CDS             340..1098
                     /locus_tag="VWX69_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9193142.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            1156..2010
                     /locus_tag="VWX69_001854"
     CDS             1156..2010
                     /locus_tag="VWX69_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU9193143.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            2122..3006
                     /locus_tag="VWX69_001855"
     CDS             2122..3006
                     /locus_tag="VWX69_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU9193144.1"
                     /translation="MKKAMVIITPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEAIHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKLKED"
     gene            3169..4908
                     /locus_tag="VWX69_001856"
     CDS             3169..4908
                     /locus_tag="VWX69_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEU9193145.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESASNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEINSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELD
                     NQLVISPDGFMIF"
     gene            4994..5311
                     /locus_tag="VWX69_001857"
     CDS             4994..5311
                     /locus_tag="VWX69_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193146.1"
                     /translation="MNCRGHETRQRIVRDFEVQPKVHIKLLANQQKHSDAVATIEDEY
                     YVFIAESKIDGKKEVIQCCMGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGS
                     GNL"
     gene            5357..5638
                     /locus_tag="VWX69_001858"
     CDS             5357..5638
                     /locus_tag="VWX69_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193147.1"
                     /translation="MWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         1899 a          844 c         1194 g         1728 t
ORIGIN      
        1 aaatcctctc cacttttaaa ctaatgtatt ataaaagcca gttgacacta gtgttacacc
       61 tgtgatagaa ttaacttgag gtgatgaaaa tggcaaccga taaaaataga ataatgatta
      121 gcttggatga taaaaatcta gagaaacttg aaaatttagt agaagatgct agagatagaa
      181 ggggaatgcg actaacaaag tcccaggtta ttgaattact cctaaatacc gttgattatt
      241 tcgatgatat tatgggggct atttactcaa aaaaataaga gcaaaattgc tattattttt
      301 tacaaattgg tgtaacacta gtgatatagg agtgatgaaa tggttgttta tattagacaa
      361 agtaaattac caagtgaggt ttcaattaat aaatacaatg ctcaagtagg tgcctactta
      421 caaggagaag aagttatttt atatcaatct ttttctgaaa taaaagagtt aacaagtgaa
      481 gatatagttg tagattatat aatggagact agagcattac taaaaatgat gggcttaaac
      541 gttccggttc atgactatcc tattgagctt aaagagtttt atggtcgaaa gatttatgct
      601 ggtattttag gagagattgt gaatatacct gataattggg gaaaatttat taagcctaaa
      661 gctggttcaa aagtctttac tggaagagtt gttaatggaa cccatgattt aataggtatt
      721 ggtctacctt tcgactatcc tatatggatt agtgaggttg tagaattcat agctgaatgg
      781 cgttgttttg tgttagatgg tcgcgtatta gatgttcgac cctatacagg tgattatcat
      841 gcacaatttg atgcaagtgt aattgatgaa gcgatatcat gttggaaaga tgcgccaata
      901 gcttatggac tagatatcgg tgttactcgc gatggcagaa cacttgttgt tgaagtaaat
      961 gatggttatg cattgggaaa ttatggccta tctcctttaa aatcaatcaa ttttcataga
     1021 gctaggtgga aagaaatggt aaaaccctat tttgaaaaaa atgaaatttt taaaatccaa
     1081 caggatgtta ttttctaaaa taaatatggt agataaccaa tataaaaagc atcaaaatga
     1141 acaaggagga atctgatgct tggagcaatt attggagata ttgtcggttc tgtttacgaa
     1201 tggaacaata tcaaaacaaa ggactttcct ttatttcgga aggactgctt ttttacagat
     1261 gacacggtta tgacctgtgc tgttgcagaa gcaattatga atggtggaca aaaagatgac
     1321 ttcattgacg cgatgaagaa atatggcaga atgtatccga atgctgatta cggtgctcgg
     1381 tttaatgcat ggctaaacag cgataaccgt gagccttata atagctttgg gaatggatca
     1441 gctatgcgta tttctccatg tgcttggatc atggactgtg gtttttatgc gaaaactggt
     1501 atatggccat catctagagg acttacgagt ctttctgcag aggtaactca taatcatcca
     1561 gaaggtgtca aaggcgctat ggctacagct gatgctatct ttctatgtcg tttttacttt
     1621 ggtggttatt gtagagagta cgagcaatca attaacgaca atcctacaga gtgtaaaaga
     1681 cgaattaagg attatataga aaaagaatac gattacaatc tatctcaaac tttagatgaa
     1741 atccgtccta actatcgttt taacgaaaca tgtcaggaaa ctgtccctca agccattatc
     1801 gcctttcttg aaagtagaga cttcgaagat gcgataagaa atgccatctc acttggtggc
     1861 gacagtgata ctctcgcagc aatcacttgt agcatagcag aggcagctta cggtattcct
     1921 gattggatca aggataaggc ctattcttac ttggatgaac ccttaaagga tgtagttagg
     1981 cgatgggaaa atagaataaa agcgtattaa tctccagtac gtcagatttc tcttttctgt
     2041 attttcattg tataatagga ttacatttac ttgcatacga cgaaatgtaa acatttctgt
     2101 ttaaaattaa ggataaaatc aatgaaaaaa gcaatggtaa ttatcacccc tacttctggt
     2161 ggcgagaagg ctttggatta caaagaaaag ctggagaata aagcaaaaga atactttgaa
     2221 tatgttgaaa ccaaaattac cgaaaaagcg ctggatgcaa cacattttgc tgaagaagct
     2281 tctcgtgagc agtatgatgc agtggttgtg tttggtggag atggaactgt caatgaagtc
     2341 atttcaggta ttgatgagag agactacatt cctaagttag ggattatccc aggcggtacg
     2401 ggtaacctca ttacaaaact tttggaaatc aatcaagaca tcgatggcgc aattgacgaa
     2461 ctggattttg atttaaccaa taagattgat atcggtaaag caaatgacaa ctattttggt
     2521 tatatcttta gtatcggttc tctgcctgag gcgattcaca atgttgaaat agaggacaaa
     2581 acaaaattcg gtattttaac ctatgctgta aataccatga agtctgtcat gacagatcag
     2641 gtctttaaca ttaaggttga gacagaaaat ggaaattatg ttggtgaagc tatccatgtt
     2701 ttggtccttt tgacaaatta cttcgctgat aagaaaatct ttgaagaaaa caaggacggc
     2761 tatgccaaca ttttgattct gaaagatgcc tctatattct ccaaattatc cgtcattcct
     2821 gatttattaa aaggggatgt tgtcgcaaat gataatatcg agtatatcaa agcgcgtaat
     2881 attaaaatct cttcagatag tgaattggag tcagatgttg acggagataa atcagataac
     2941 ctacctgtag aaatcaaagt cctagctcag cgagtagaag tattttcaaa actgaaagag
     3001 gattagtata tagagaaagc cttttttaag gctttttgta tactttaaaa gatagttcct
     3061 ttaacaacgg acattccttg caaatagttt acaaaaatag tatactggat ttattgagtt
     3121 tgaaaacgtt tgcgtaaaat ttgaatgaat actttaggag acaaattgat ggaattgagt
     3181 gctatttacc ataggcctga gtcggagtat gcctatcttt ataaggataa gaaactccat
     3241 attcgaattc gaactaagaa aggggacatt gaaagcatca acttgcacta tggggaccct
     3301 tttatcttta tggaggagtt ttatcaggat acaaaagaaa tggtcaagat aacttctggt
     3361 accttatttg accattggca ggttgaagtg tcagttgact ttgcacgtat ccagtatctc
     3421 tttgagctca gagatacaga aggtcaaaat attttgtatg gcgataaagg gtgtgtggaa
     3481 aattctctag aaaatcttca tgcaattggg aatggattta agttgcctta tcttcatgag
     3541 attgatgcct gcaaagttcc tgactgggtt tcaaatacgg tatggtatca gatatttcct
     3601 gaaagatttg ccaatggcaa tgctctatta aacccagaag ggactttaga ctgggattca
     3661 tctgtcacac ctaagagcga tgatttcttt ggtggtgatt tacaggggat tattgatcat
     3721 atggattact tgcaagactt gggtattact ggactatatc tttgtcccat ctttgaatct
     3781 gcaagcaatc acaagtacaa tacgacagat tactttgaaa ttgaccgtca ttttggagac
     3841 aaggagacat ttcgggaact ggtggatcaa gcgcatcatc gtggcatgaa agtcatgctg
     3901 gatgcggtat ttaatcatat tggttcgcaa tctcttcaat ggaaaaatgt cgtcaaaaat
     3961 ggtgaacagt ctgcttataa ggattggttc catattcaac aattcccagt gacaactgaa
     4021 aagctagtta ataagagaga cttaccctat catgtttttg gtttcgagga ctatatgcct
     4081 aagctaaata cagccaatcc agaggtcaag aattatcttt taaaggttgc gacttattgg
     4141 attgaagagt ttaatatcga tgcttggcgt ttggatgtgg ctaatgagat tgaccatcag
     4201 ttctggaagg attttcgtaa ggcagtttta gctaaaaatc ctgatcttta tatcctagga
     4261 gaagtctggc atacatctca gccttggcta aatggagatg agttccatgc cgtcatgaat
     4321 tatcctttat ctgatagtat caaggactat ttcttacgag gaattaagaa gacagaccag
     4381 ttcatcgatg aaatcaatgg agagtctatg tattacaagc agcagatttc agaggtcatg
     4441 tttaatctct tggattcaca tgatacagag cgaatcctgt ggacggccaa tgaagatgtt
     4501 caactggtta aatcagcctt agcctttctc tttttacaaa aaggaacacc gtgcatttat
     4561 tacggaaccg agctagcctt gactggagga ccagatccag attgtcgtcg ttgtatgcct
     4621 tgggaacgtg tatcaagtga caatgatatg ctgaacttta tgaagaggct gattaagatt
     4681 cggaaatacg cgtcagtaat catttcgcat ggcaagtata gccttcaaga aatcaactct
     4741 gatctagtag ctctggaatg gaaatacgaa ggacggatcc tcaaagcaat attcaaccaa
     4801 tcaacagaag attatctttt agagaaagaa gcagtagcac tagcaagcaa ttgccaagaa
     4861 ttggataatc agcttgtcat ctctccagat ggatttatga ttttctaaaa actagttgat
     4921 gaagattatg gtacatttca taccttatat agtataataa ggctagttac taaacttgta
     4981 aaggagaact taaatgaatt gtagaggaca tgaaacaaga caaagaattg ttagagattt
     5041 tgaagttcag cctaaagtac atattaagct gttagcaaat caacaaaaac atagtgatgc
     5101 agtagcaact attgaagatg aatattatgt atttatcgct gagagtaaaa ttgatggcaa
     5161 gaaggaagtt attcagtgtt gcatgggtgc ggcaagggat tttttagaac taattaatca
     5221 caaagggcta cctcttttta atccgcttgt aggtgattct catgtaaata atagacaaga
     5281 atatgacaat acagggagtg gaaatttata acctgaaaag tggaatgaaa ctgcaaagca
     5341 gctttataat gctataatgt ggttgattat tttatggaat gctaagccgg atacaccttt
     5401 atttaatttt aaagacgaag taattaagta taaaacatat gagccttttg aaagcagtat
     5461 aaaaagagta aatactacta taaagaatgg tagtaaaggg aaaactctga ctgagatgat
     5521 taatggctac agagcggata acgatattag agatgaaatt tgtaacttta atattctgaa
     5581 aaataaaatt cgtgatatga aagaccaaca aggaaataca atggaatctt acttttagtt
     5641 attgttgaat tttgggtatt ctata
//
LOCUS       DAVKBK010000081         5662 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVKBK010000081 DAVKBK010000000
VERSION     DAVKBK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.081"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="VWX69_001859"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="VWX69_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU9193148.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1317..2021
                     /locus_tag="VWX69_001860"
     CDS             1317..2021
                     /locus_tag="VWX69_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9193149.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2014..3363
                     /gene="vicK"
                     /locus_tag="VWX69_001861"
     CDS             2014..3363
                     /gene="vicK"
                     /locus_tag="VWX69_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU9193150.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3365..4174
                     /locus_tag="VWX69_001862"
     CDS             3365..4174
                     /locus_tag="VWX69_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9193151.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4265..4507
                     /locus_tag="VWX69_001863"
     CDS             4265..4507
                     /locus_tag="VWX69_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU9193152.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4509..4763
                     /locus_tag="VWX69_001864"
     CDS             4509..4763
                     /locus_tag="VWX69_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU9193153.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4810..5505
                     /locus_tag="VWX69_001865"
     CDS             4810..5505
                     /locus_tag="VWX69_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEU9193154.1"
                     /translation="MKKKWLFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
BASE COUNT         1764 a          939 c         1266 g         1693 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattc ctggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgc ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggcta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg
      661 attttaatca agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggccccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg cacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga
     1321 aaaaaatact aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga
     1381 ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg
     1441 aagcagagca accagatatt attattctgg atttgatgct tccagaaatt gatggtttag
     1501 aagttgctaa gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag
     1561 atagtgaatt tgataaggtt atcggtttgg aacttggggc agatgactat gtaacgaaac
     1621 ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta
     1681 tgccagtaga tggtcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag
     1741 aaattgttcc agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc
     1801 gtgaatttga gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac
     1861 acttgcttga gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga
     1921 ctgtacgacg tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga
     1981 cgcgccgtgg tgtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt
     2041 tttaccagag attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc
     2101 ttattactgg aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa
     2161 gatttgattg caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc
     2221 aatattacca ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta
     2281 gaacaagaga gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg
     2341 accaaccgtc ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg
     2401 gttaaggaag atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat
     2461 gaattgcgtg atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat
     2521 ggcgaatatt tgaaccttcg agttcgcttt gccttgatac gtcgagagtc tggctttatt
     2581 tcaggtttgg tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga
     2641 agactctttg tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc
     2701 tatcttgaag ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag
     2761 gtttctcttg atgagaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca
     2821 cgtattgata atgctaccag tcacctagat gtggaactga ttaacttcac tgcttttatt
     2881 acctttatcc tcaatcgttt tgacaagatg aaaggacagg aaaaggagaa aaaatatgag
     2941 ttggtgagag attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg
     3001 caggttgtcg acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc
     3061 actgtcagaa tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg
     3121 gggattccta agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct
     3181 agaagtcgtg cacaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattatcaaa
     3241 caacataagg gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt
     3301 gtgctccctt atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac
     3361 tagaatgagt gaaataggct ttaaatacag tattttagcg tcgggttcca gtggaaattc
     3421 tttttatctg gaaacctcaa aaaagaagct tttagtagat gcaggcttgt ctggcaagaa
     3481 aattaccagt ctgctagctg aaattaaccg taagccagaa gacctggatg ccatcttgat
     3541 tacccatgag cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat
     3601 ggatctttat gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa
     3661 ggtggattct tcgcaaaagc atatttttga aatgggtaaa accaaaacct ttggagatat
     3721 cgacatcgag agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat
     3781 gaaggatgat aagagttttg tccttttgac agatacaggt tatgtcagtg accgtatggc
     3841 gggcattgtc gaaaatgcgg atggctatct tatcgaggcc aaccatgatg tagagatttt
     3901 gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc ctatctgacc ttggtcacct
     3961 ttctaacgag gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat
     4021 ttaccttggg catttatcta aggaaaataa tatcaaggaa ctggctcata tgaccatggt
     4081 caatcagctg gctcaagctg atctgggagt cggagtagac tttaaggttt atgatacctc
     4141 accagatacc gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt
     4201 tatattgact gaacacctaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca
     4261 aaagatgact actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat
     4321 ggctaagttt gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct
     4381 agaagatgaa tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagactt
     4441 ggaaaaagga gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga
     4501 tgaataattt gtataaatta gttccaacaa gacgttttat caagcaattg aaaaaattgg
     4561 accgttatac gcagaagcta attacaaact atttacaaac caatgttttg gaaggtccaa
     4621 gacgacacgg aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta
     4681 attatcgagt tatcgtacaa attgtagatg atgaattagt cgttgctact ctagaagttg
     4741 gtcatcggag agatatttat tgaattaaag ctgagtaata acaatataga aagtaaggag
     4801 agtaaaaatt tgaagaaaaa atggttattt gcagattatt atgatacaac aattatttta
     4861 cttgctttaa tctctgttat tctggtatta cttggatttg ctgagatgac tgatttggac
     4921 aatccgcctt atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt
     4981 tggcgctttt ttattactaa aagaaaatgg cgctttattc ttgaaaatat ttttgattta
     5041 ttgaccattc tccctttaaa tgctattttt acagtgtttc gattaggacg tatcttccgc
     5101 ttagcaaggc tgacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca
     5161 ggtaaactag aaagaaaaat tagtagattc ttacgaacaa atggattgat ttatatcttg
     5221 tatgttaata tctttattgt tctagtaggg agttcgattt tatccgttgt tgaagaaaaa
     5281 tccttctcag atagtctttg gtgggctctt gtgacagtaa ctactgttgg ttatggtgat
     5341 attgttccag tttccctttt tgggaaatgg ctagcagttt tactgatgct tgtcggtatt
     5401 ggaacaatag ggatgctaac aagtgctttg acgaactttt ttgtaaagga taatccagat
     5461 gaacagataa aacttgataa actcaaagac gaattatcga gctaaagaat attaatagag
     5521 aaacaatctg aaaaaatcga agaactacat tgaatgataa aagacttagt tgaaaaaata
     5581 tcataaaggt gagacaaaat aaaacttgat tcgaggagaa atcaagtaag ttttgacaca
     5641 atagaacgca tattatcagg ta
//
LOCUS       DAVKBK010000082         5455 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVKBK010000082 DAVKBK010000000
VERSION     DAVKBK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.082"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            89..772
                     /gene="rpiA"
                     /locus_tag="VWX69_001866"
     CDS             89..772
                     /gene="rpiA"
                     /locus_tag="VWX69_001866"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU9193155.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            786..1997
                     /locus_tag="VWX69_001867"
     CDS             786..1997
                     /locus_tag="VWX69_001867"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU9193156.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            1999..2532
                     /locus_tag="VWX69_001868"
                     /pseudo
     CDS             1999..2532
                     /locus_tag="VWX69_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285096.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            2556..3365
                     /locus_tag="VWX69_001869"
     CDS             2556..3365
                     /locus_tag="VWX69_001869"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9193157.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            3841..4236
                     /locus_tag="VWX69_001870"
     CDS             3841..4236
                     /locus_tag="VWX69_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU9193158.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            4246..4821
                     /locus_tag="VWX69_001871"
     CDS             4246..4821
                     /locus_tag="VWX69_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9193159.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            4846..5358
                     /locus_tag="VWX69_001872"
     CDS             4846..5358
                     /locus_tag="VWX69_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU9193160.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNFPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         1672 a          970 c         1268 g         1545 t
ORIGIN      
        1 aaataagcag tattctaaag gtacttttag atgaaataaa agcctttaca tggtataata
       61 gaggtagctc tttaatggag gtgtttgagt ggaaaatctg aagaaaatgg caggtatcaa
      121 ggctgctgag tttgtcaagg atggaatggt cgttggactt ggaacaggct cgactgccta
      181 ttattttgtc gaagaaatcg gtcgtcgtat caaggaagaa ggattgcaga ttatagctgt
      241 aacgacttct agtgtgacca ctaaacaggc agaaggcctt aatatcccac tcaaatctat
      301 tgaccaagta gactttgtcg atgtgacagt tgatggcgca gatgaagtgg atagtcagtt
      361 taatggaatc aaaggtggtg gtggtgctct tctgatggag aaggttgttg cgacaccatc
      421 aaaagaatac atttgggtgg tggatgaaag caagctggtc gaaaaactag gtgcttttaa
      481 attgccagta gaagtggttc agtatggtgc agaacaggtc tttcgtcgtt ttgaacgagc
      541 tggctacaaa ccaagtttcc gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa
      601 ttttatcatt gacctcgcct tggatgtcat tgaaaatcca attgcttttg gacaagaatt
      661 ggaccatgtc gttggtgttg tggagcatgg tttattcaac caaatggtgg ataaggtcat
      721 cgttgctgga cgggatggag ttcagatttc aacttcaaaa aaaggaaaat agaagggggc
      781 ataagatgtc taaatttaat cgtattcatt tggtggtact ggattctgta ggaatcggtg
      841 cagcaccaga tgctaataac tttgtcaatg caggggttcc agatggagct tctgacacac
      901 tgggacacat ttcaaaaaca gttggtttga atgtcccaaa catggctaaa ataggtcttg
      961 gaaatattcc tcgtgaaact cctcttaaga ctgtagcagc tgaaagcaat ccaactggat
     1021 atgcaacaaa attagaggaa gtatctcttg gtaaggatac tatgactgga cactgggaaa
     1081 tcatgggact caacattact gagcctttcg atactttctg gaacggattc ccagaagaaa
     1141 tcctgacaaa aatcgaagaa ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt
     1201 attcaggaac ggctgttatc gatgattttg gaccacgtca gatggaaact ggagagttga
     1261 ttatctatac ttcagctgac cctgttttgc agattgctgc ccacgaagac attattcctt
     1321 tggatgaatt gtaccgtatc tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc
     1381 ttcttggtcg catcattgct cgcccttatg taggtgaacc aggtaacttc actcgtacgg
     1441 caaaccgtcg tgacttggct gtatctccat tttccccaac tgttttggat aaattgaatg
     1501 aggctggtat cgatacttat gctgtgggta aaatcaacga tatctttaac ggtgctggta
     1561 tcaaccatga catgggtcac aacaagtcaa atagtcatgg aattgataca ctattgaaga
     1621 ctatgggact tgctgagttt gaaaaaggat tctcattcac aaacctagtt gactttgatg
     1681 ccctttacgg ccatcgtcgt aatgctcacg gttaccgtga ttgcttgcat gagtttgatg
     1741 aacgcttacc tgaaattatc gcagctatga gagagaatga ccttctcttg attactgcgg
     1801 accatggaaa tgacccaacg tatgcaggaa cggatcacac tcgggaatat attccattgt
     1861 tggcctatag ccctgccttt aaaggaaatg gtctcattcc agtaggacat tttgcagata
     1921 tttcagcgac tgttgccgat aactttggtg tggaaactgc tatgattggg gaaagtttct
     1981 tagataaatt ggtataagat gacgcgctat gctttgctgg tgagaggtat caatgttggt
     2041 ggtaagaata aggtcgtcat ggcggagctt cgtcaagaat tgacaaactt gggactggaa
     2101 aaggttgaga gctacatcaa cagtggcaat attttcttta cttcgataga ttccaaagcc
     2161 caattggttg aaaagctaga gactttcttt gcagtccatt atccatttat tcagagcttt
     2221 tctttactga gtctagagga ctttgaggcg gaacttgaaa atctaccagc ttggtggagc
     2281 agagatttgg cacgaaaaga ttttctcttt tacactgagg gtttggatgt ggaccaagtc
     2341 atcgcgacag ttgaaagttt agagctgaaa gatgaagtgc tttattttgg aaaacttggg
     2401 attttctagg ggaaattttc tgaagaatcc tattctaaga ctgcctatca taagtacttg
     2461 ctgaggtgcc tttctaccgc cacattacta ttcgtaatgc taaaaccttt gacaaaattg
     2521 gtcaaatgct aaaaaaataa taaaggagac acacaatgac atttttaaac aaaatccatg
     2581 aaactgctac tttcctgaaa gaaaagggaa ttgcagcccc tgagttcggt ctaatccttg
     2641 ggtcaggact tggagaattg gcagaagaaa tcgaaaatcc agttgtagta gactatgctg
     2701 agattccaaa ctggggccgt tcaacagtag tcggtcatgc tggtaaattg gtatatggtg
     2761 aactggcagg tcgcaaggtc ttggctcttc aagggcgttt ccatttctat gaagggaatc
     2821 ctctggaagt ggtgactttc ccagttcgtg tgatgaaagt tcttggatgt gaaggtgtta
     2881 ttgtaaccaa tgcagctggc ggtatcggat ttggtcctgg taccttgatg gctatctcag
     2941 accatatcaa catgacgggg caaaatccat tgatgggtga aaacttggat gactttggcc
     3001 cacgtttccc agatatgtct agggcctaca caccagaata ccgtgctact gcccatgaag
     3061 tggctaaaaa acttaatatc aagcttgatg aaggtgtcta tatcggagtt actggtccga
     3121 cttatgaaac accagcagaa attcgttcct ataagacact gggagcagat gcagttggta
     3181 tgtctacggt tcctgaagtt atcgtggcag cccactctgg cttgaaagtt ctgggaattt
     3241 catgtatcac taactttgcg gctggtttcc aagaagaact caatcacgaa gaagttgtag
     3301 aagtgactga acgtgttaaa ggtgatttta aaggcttgct taaagcgatt cttgctgaat
     3361 tgtaagaaaa aagatttaaa agggggagtg cctctgtctt ttcaggattg actgcctatc
     3421 cgtattaaag aagaaacaga ggaatactat gagcttcttc ctgctcttat aactgaaaga
     3481 agcggaagaa taggtgtgtc tgatctgata gccagcattg tgaaagacaa gattctagga
     3541 tactagcatt agcttcctag ccaagcagac tagtatgata aggagagatg agaatgaatt
     3601 gactttctga atttctcagt cttatcatat atagcacaat gagatttcgc ttgagtctgc
     3661 ttgtaaataa acgaaaagaa agataagaaa taatgaaaat tggtcaacga attatgcgct
     3721 ttggcataaa aaattaagta tcggagttgt atctgttgta gtcggctttg atttctagct
     3781 ccagctggaa tttcagccaa tgaagtaaag caagatgtaa caactgaagt ggtaataggt
     3841 gtgctagatt ctaaggagga attgaaagag tcagaaaatg atgctccaaa actagaaact
     3901 cctcttagag aggagccaag actagctcct caaacgcttc cggaagcaag tgaagttctt
     3961 gaaaacaaaa gggaagagtc aaaagtagag ataacagagc cagctcaagc ggatgacatc
     4021 cgcaaggttg ttggggaatt agccaaggat ataagtatta ctaagttgta tatgacaggt
     4081 cattctcttg gaggctacct agctcagatt gcagcggttg aagattacca aaaatatcct
     4141 gatttttata accatgtatt gaggaaagtg acaactttca gtgctcctaa agtgattact
     4201 tccagaactg tttgggatgc taagaatggt ttctgagatg ttggtttgga aagtcgtaaa
     4261 ttagctgtta gtggaaaaat taagcattat gtggttgata atgacaatgt tgtgactccc
     4321 ttgattcata ataatcgtga tattgttaca tttacaggta attcacgctt taaacaccgt
     4381 tctcgtggct attttgaaag tccaatgaat gatattccta actttaatat tggtaaacaa
     4441 gctaccttgg ataaacatgg ttatcgtgat ccgaaattgg ataaagtgcg attctttaag
     4501 aaacaggctc tacctcaatc ttctagtcaa ccaagcgctg aaccaatgga aaatattgcc
     4561 ttaggaaaac aggttactca aagttcgaca gctttcggag gagatgctag aagagctgtg
     4621 gatggcaaag tcgatggtaa ctatggtcac aattctgtca ctcatacaaa cttccaatct
     4681 aagccttggt ggcaagtaga tttggctaaa gaagaaacca ttcgccaaat caatatttac
     4741 aaccgaacag acactgccca ggatagattg gcaaactttg atgtcattct tttagacagt
     4801 tctggtaaag aaattgagtg aaaacgtata atatctccta aagatgtgtc agcacaaatt
     4861 acgattaacc ataaaaaagc gcgctatgtt cggattgggc tagaaggcta taatgccctc
     4921 agtcttgcag aagttgaagt tttccgcttt atagctacga atgctgaaac ggcgacacaa
     4981 gtttctaagc cagttcaacc aatcagtcag actcctgtga aagataaaac attgacaatt
     5041 caacacagtg gagcttacat tgcccgctac tccataactt gggaagaagt tccagtagat
     5101 aaagatggaa accaagttgt tcgtagtcat tcttgggaag gaaacggttg caaccagact
     5161 gcaggttttg tcctcaactt cccaatcaaa gaaaatatga gaaatctgcg agttaagatt
     5221 gagaaaaaga cgggcctact atggaataga tggcaaacaa tctatgaaaa cagaccaatt
     5281 ttagctcaac cccaccgtaa aattacccat tggggtacga cattgaattc caaggtgagt
     5341 gacgatgatg tcttgtaatc tgatggtaca atgacagtta gtttgtctag tttataagaa
     5401 agtactatct gagcttgaat agaactcagg tagctctctg tgaaagaaca aaatt
//
LOCUS       DAVKBK010000083         5191 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVKBK010000083 DAVKBK010000000
VERSION     DAVKBK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5191
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.083"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(349..1077)
                     /locus_tag="VWX69_001873"
     CDS             complement(349..1077)
                     /locus_tag="VWX69_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9193161.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1235..2644
                     /locus_tag="VWX69_001874"
     CDS             1235..2644
                     /locus_tag="VWX69_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9193162.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKSIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2662..3957
                     /locus_tag="VWX69_001875"
     CDS             2662..3957
                     /locus_tag="VWX69_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9193163.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVNRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3962..4270
                     /locus_tag="VWX69_001876"
     CDS             3962..4270
                     /locus_tag="VWX69_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9193164.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4267..4575
                     /locus_tag="VWX69_001877"
     CDS             4267..4575
                     /locus_tag="VWX69_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9193165.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1749 a          874 c          941 g         1627 t
ORIGIN      
        1 aattcatttc tagcaatttg ttagaagtca cagtctacta ttctaacctc agtatactat
       61 atgtgttaca agaaaagact caaaaacttc tcgtcagtgt aagaatattt gaaacactat
      121 ttaaaactaa ataactataa gaagtagatc aggtgaacaa tttcagtacc tactctataa
      181 gctatacgaa gatatttttc aacatgatgg ataaaacgat cactctttta aagccatctt
      241 atttagaaaa gagaaaccat ttaagcatag atgggacctt cttgccctgt tttaaatttt
      301 tcttaaacta gagtctgtaa aagattggct tcattttcac attttctcct aggaggaatg
      361 tcgtaatgca aaagaattaa attcaaataa atcatagcga tgacgactaa tcgagtactc
      421 aaacggagtt ccgttatcca aataagccac ttgttctact tcaaataccg gttccgttgg
      481 aaggagctgc aagtaatgtt gctcattttc tgaactagaa gaagctcgta agatttttgt
      541 agcactggca atatgcaatc ctaactttcc ttcaatgtaa ttgtaaatcg atttttgtaa
      601 aatatcttca gtaatacctg gaataacatc ggtactcata taagtttgtt ccagaacata
      661 aggtttaccg tcaataatac gcaggcggta aatattataa actggactct gcaaagcgac
      721 ctgtagtttt tctgctaaaa attcatttgc aaattctaat ttgaagtgaa taatcctcga
      781 gtcaattgta gaatgagcat cttcagatat ttttgtcagt ccccggatat ctctttctgg
      841 aacgattaat tttctttttg agctgccacg agagagaaca aaggttccct gcccacgttt
      901 tctaaaaatt aagccctcag aaactaacaa gtctaaagct tttttgatcg tcattcgact
      961 acaggcaaac tgtttagcta atgtcatttc atcaggtaat tgttcgttca tggtatattt
     1021 attacaaaga atcttttcac gaatctcatt gtaaataaat aaatattttg tactcattta
     1081 atctggttct ctctataata ttctaatagt agtataacaa agttcaagaa atgaggcaaa
     1141 cacaagatat gtatcaacaa tttttaaaaa tgtctagaca aattttaaaa ttatgctata
     1201 ctttatgtat agaataatag aaaggaggtt gagcatgaaa aaaaagttag tatttcctaa
     1261 tctgttttgg tggggagcag cttctagcgg acctcagaca gaaggtcaat atggaaaagt
     1321 acatgaaaat gtgatggact actggttcaa aacgcatcca gaagattttt tcgataatgt
     1381 cggacctctt gtagccagta acttttttca tacttacacc gaagatttcc acttgatgaa
     1441 ggaaattgga gttaattctt tccgcacttc catccaatgg agtcgactca tcaagaattt
     1501 agagacaggt gagcctgatc caaaaggtat tgctttctac aatgccatca ttgaagaagc
     1561 taaaaagaac cagatggatc ttgtgatgaa tttacatcat tttgatttac cagtggaact
     1621 tcttcaaaaa tacggtggtt gggaaagcaa acatgtagtg gagttattcg tgaagtttgc
     1681 caagactgct ttcacatgct ttggagataa ggttcattac tggacaactt tcaatgagcc
     1741 aatggtcatt ccagaagcag gatacttata tgctttccat tatccaaatc taaaaggaaa
     1801 gggaaaagag gccgtacaag tcatctataa tctaaacctt gctagtgcaa aagtgattca
     1861 actatatcgc tcattagaac ttgatggaaa gattgggatt attttaaact tgacacctgc
     1921 ttatccaaga agtaattctc cagaagactt agaagcaagt cgatttacag atgacttctt
     1981 taacaaagtc ttcttgaatc cagctgttaa aggaactttc ccagaaagat tggtaaaaca
     2041 gctagagaga gatggcgtgt tatggagtca taccgaaaaa gagcttcaac tgatgaaatc
     2101 aaatacggtt gattttcttg gagtaaacta ctaccatcca aaacgtgttc aagcacaagc
     2161 aaatcctgag gaatatcaga cgccctggat gccagaccaa tacttcaaag agtatgaatg
     2221 gccggagcgt cgcatgaatc catatcgtgg ttgggaaatt tttccgaaat ccatttatga
     2281 tattgctatg attgtgaagg aagaatatgg taatatccca tggtttatca gtgaaaacgg
     2341 aatgggtgtt gaaaacgaag cacggtttat cgatgaaaat ggagttatcg atgacgtgta
     2401 tcgtattgaa ttttatgaag aacatttaag atggctacat aaagccattg aagagggaag
     2461 tcactgtttt ggataccacg cttggaccgc atttgattgc tggtcttgga ataatgcata
     2521 taagaatcgt tacggattta tctccgttga tttagaaacg caaaagagaa ccatcaagag
     2581 ctcaggaaga tggtatcgca aagtaagtga caataacggt tttgaagtag aaattgagga
     2641 gtaaagagag gagatattca tatgaaaaac tcaaaattta tagaccaatt tgccaccttt
     2701 gctggtaaac tagggaacca aattcattta aaaaccctaa gagatgcatt cgtaacagta
     2761 atgccattat atattttggc aggtttaatc gttcttttga acaacacggt atttaagtgg
     2821 attttccaag gggatacatt aacaagattc caatattggg gaataacaat tgcaaacggt
     2881 actttaagta tttcaggtat gattattgct gtaatggttg gttatttctt agctaaaaac
     2941 agagatttcg aaaacccgtt agcagcatca atgctatcat tagtttcttt aattgtgatg
     3001 atgccaaata cagtttctgt agttcctgac ggagcaaaag atgctgtaaa catttcaggt
     3061 gttctttcat tcaacaacac aggtacaggc gcaatgttcg ccggggttat cgtagcgatt
     3121 attgcaacag aattattcat tgaattatca aatgttaaag ctttacaaat gaaccttggt
     3181 gaaaatattc caccagctgt taatagatca tttagcgtat tacttccagt catgaccgtc
     3241 atctccttat ttggggttgt ttcagcatta ttattcaata taactggaat gaacttaatc
     3301 tcaatcatta caatctttat tcaagaacca attcgtcata ttggtacaag cttaatcggg
     3361 gtcattatta tttactcttt aggaaatatg ttatggctat ttggtattca ccaagcagtt
     3421 atttacagtg ccatcctaga accattacta ttaattaaca ttactgaaaa catcactgca
     3481 gcaaataatg gacaagccat tccacacatc atcaacctat cacaaataca aacattcgct
     3541 ttaatgggtg gtagtggatc tacattatgt ttattaatag caacattctt agtgagtcgc
     3601 aatgctgtct ctaaaaacgt ggctaaatta tcttttggac ctggtatctt caatatcaat
     3661 gaaccagtat tattcggtta cccaatcgtt tataacattt cattagctat tccatttatc
     3721 acagttccag tccttggtat tttaatcagc tacttagcaa cagttacagg attcatgagt
     3781 cctgcattta tacaagttcc ttggactaca ccagtattct taaatgcatg gttagcaaca
     3841 gcaggggacg tgagagcagt tctagttcaa ttcatcatct ttgcacttgg agttcttcta
     3901 tacattccat ttatcaaagt taatgacaaa gttgttgaac aagaaatgga aggttaagat
     3961 tatgaaacaa attttattag tatgtaatgc gggaatgtcg acaagtatgc ttgttaaaaa
     4021 aatgcaacaa agtgcgactg aacgtgggat tgaaatctct atccaagcaa aatcaatgac
     4081 agaagctaaa aagaatatcc atgaagcaga tgtcattcta attgggccac aaattcgtta
     4141 tgagttactt gctgtgaaag aaattgcagg aaatatccct gtagatacca ttgatatgcg
     4201 ggattacgga atgatgaatg gagcaaaagt tctggaacaa gcacttgcat ggataggaga
     4261 aataagatga cagaagaaat ggaatatatc tgttttcagc tcattgccaa tagtggagca
     4321 gccaaatcat cctttattga agccatccaa ctagctaagg caggaaattt aaaagaagcg
     4381 aaaattaaag ttgaagaagc ggaagactcc ttagtagaag cgcacaagat tcactctaat
     4441 ctcatacaaa aagaagctac tggagaaaaa ataggattct ccttgctatt tatgcatgca
     4501 gaagaccaaa tggcttcaac agagattatt cagttgctat ctaaagaatt catcgatctc
     4561 tatcaaaata aataggaaca ctgtcattcc catctgtctt tattaatgac gactacattg
     4621 taggaacctc caaaagttgg acaaaatgat tgaaaggatt ggatcctgca ttacacaaga
     4681 tccaatcctt ttcttttact ctagttttta taatatgttg aatctagaat agtccactgt
     4741 agtttctaaa aaattgctgg aaatggatgt taagctccaa tttatttgtt tatatcttat
     4801 ttcagtttac tatactagct tattattcta gtgaaaaatt gaatgagcca ctatttattt
     4861 aatatgtatg atgagggaat gactcaaaaa cttcttgtcg atataagaat atctgagata
     4921 gtattttaaa acgaaaggac tataaaagct catttccttc gcacttattt tatagagatc
     4981 tatcattata ctctttagaa atcaaaaagc aacacacctt gtcatcgttt tatcgtaaat
     5041 ctgttaatga gggggctagt cttatctgca atctcaaatc agtgttttga gctgaatggc
     5101 actcgttttc tagtttgctc tttgatttta attgggcctt agtaaatact actcttaaat
     5161 taaactatag tgaattgaaa taagatgtga a
//
LOCUS       DAVKBK010000084         5163 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVKBK010000084 DAVKBK010000000
VERSION     DAVKBK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5163
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.084"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            70..597
                     /locus_tag="VWX69_001878"
     CDS             70..597
                     /locus_tag="VWX69_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9193166.1"
                     /translation="MEDYCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNT
                     RKAQGRHLEQEGNIKHALIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQ
                     TLMESLSDDDYDFAFDEALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKY
                     ECYSPLNNLELDDFE"
     gene            complement(763..834)
                     /locus_tag="VWX69_001879"
     tRNA            complement(763..834)
                     /locus_tag="VWX69_001879"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(799..801),aa:Arg,seq:cct)
     gene            complement(876..1223)
                     /gene="rplS"
                     /locus_tag="VWX69_001880"
     CDS             complement(876..1223)
                     /gene="rplS"
                     /locus_tag="VWX69_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU9193167.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1342..1671)
                     /gene="crcB"
                     /locus_tag="VWX69_001881"
     CDS             complement(1342..1671)
                     /gene="crcB"
                     /locus_tag="VWX69_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9193168.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1665..2039)
                     /gene="crcB"
                     /locus_tag="VWX69_001882"
     CDS             complement(1665..2039)
                     /gene="crcB"
                     /locus_tag="VWX69_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9193169.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(2036..2302)
                     /locus_tag="VWX69_001883"
     CDS             complement(2036..2302)
                     /locus_tag="VWX69_001883"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU9193170.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2418..2861)
                     /locus_tag="VWX69_001884"
     CDS             complement(2418..2861)
                     /locus_tag="VWX69_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU9193171.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2965..3900
                     /locus_tag="VWX69_001885"
     CDS             2965..3900
                     /locus_tag="VWX69_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU9193172.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3954..4238
                     /locus_tag="VWX69_001886"
     CDS             3954..4238
                     /locus_tag="VWX69_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU9193173.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4295..4513)
                     /locus_tag="VWX69_001887"
     CDS             complement(4295..4513)
                     /locus_tag="VWX69_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193174.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(4510..5084)
                     /locus_tag="VWX69_001888"
                     /pseudo
     CDS             complement(4510..5084)
                     /locus_tag="VWX69_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1647 a         1086 c          895 g         1535 t
ORIGIN      
        1 aaagaagcac aaaatcttat tatcgaacat agtgactata tcaaagcata ctatgataaa
       61 gacataacta tggaagatta ttgtaaagaa aaaaacaata tctcttttaa agcaactttt
      121 ggtgatataa aatggagtct cttaaataaa caagctcata ggaatactgt atcaggagat
      181 tttggatgct tatctaacac acgaaaggct cagggaagac atttggaaca agaaggtaat
      241 attaaacatg ctttaatata ttacatagaa tctttgataa ttactatttc aggattagaa
      301 aacaattttt cagccactga ttatccagta tattatcccg attcgatacc tgactactca
      361 ctaaaacata ttcaaacatt aatggaatca ttatctgatg acgattatga ttttgctttt
      421 gatgaagcat tatttcgctt ctcaattttg aatgcaaatc attttttatc taaggaagat
      481 attgactatt taagagttaa tttacctcgt tccactgctg aagaaataaa caattactta
      541 aagaaatatg aatgttatag tcctttaaat aatttagaac ttgacgattt tgaataaatt
      601 gactatacaa acatttatat actcgatata gtctcaattt tatctgatga ttgcccaaat
      661 ttttcaataa taaaacgcat aatattatgg agacaatccc ctatattatg cgttctttta
      721 atatcaaaga ctttttgaca aacttcttcg atatctaatt actgccccct gcaggaatcg
      781 aacctgcaac tactccttag gagggagttg ttatatccat tgaactaagg gagctagata
      841 aaaactctgc tgaaaagcag agttttttag tcgaattaac gacggatttc tttgatacga
      901 gctgccttac cttgaagagc acgcaagtag tacaatttcg cacgacgtac tttaccgtaa
      961 cgaacaactt cgattttttc aacacgtgga gtgtggattg ggaagatacg ctcaacacct
     1021 acaccgttag agattttacg aactgtgtag ttttctgaga ttccagcacc tttacgtgcg
     1081 ataacaacac cttcaaaaat ctggatacgt tcacggttac cttcgacaac tttcgcatgt
     1141 acacgaacag tgtcaccagg acggaatgat gggatatctg tacgaagttg accttcagtc
     1201 aagctttgga ttaatggatt cattttattc tcctatcttt gtcaatcttg aggaatcttc
     1261 ctcagcggat aaactgtatt tttgtgcgtc cattacacac aagatatagt ttaccaaatt
     1321 tctaaaaaaa agtaaagaaa tttatagcaa aattcctaaa aaaatcgcaa ccaaaccacc
     1381 tatgtaagtc aaagtcaggt aagaataaaa gaccttctta tcacttagca gtctttgaag
     1441 ttcgtcattc aaggtcgaaa aagttgttaa accgccacaa aatcctgttg ctagaatagc
     1501 atatacttcc ttagactcta catgattgta gaatactcca attaaaaaac aacctaaaag
     1561 attagctatg agcgttccga gtggcaattt agaagcttga ttatagcgag aaaagaaata
     1621 ccgtacgagt gctcccaagc cacaggcgat tgcaagatag acgattacca tttcttcctc
     1681 cccaaatagt aagctaaaag caggcctcca ccgatactca aaagcaaata cagtatcaaa
     1741 ctaagataac gccctgtatc aagcagcttc acagtatcaa gcattaggct ggaaaaagtt
     1801 gttaaacctc cgcaaaaacc cgtccccagt gctaaaatca agcccttact agtcccctta
     1861 tagaccagat agcccttgac aagataaatc aagcagaaaa ttcccagata gttgacaaag
     1921 agagtgcccc aagggaaatc tggactggct ggtaaccaag tggaaactag gtagcggaca
     1981 agtccgccca acatagcagc tagaaaaatc cctagcggat aaaattgttc ttttttcatt
     2041 tgatattttg atcctgataa tcacgcgaac gtttgagtat gtccgaaaaa gtcgcgacaa
     2101 tagtctcctg atagcgcttg tcctctacac gacttctaac cttttcaaaa ataactgctt
     2161 ctctcttagt atctaaaatc ggtttccctg aagccttctt ataagcgaca actccttcaa
     2221 ctaagtgcat tcgttcttct aacagtttga caatttggtc gtcgatttga tcgatttctt
     2281 gacgaataat atctaaatcc atacagtctc ctcctttatt tgaattattg tatcaaaaag
     2341 ccatcaatta ggctagtaaa atcccaactc tcgataagaa aaatgcactg attgattaca
     2401 tcagcgcact tttatgctta tcctacttta gcagccaatt cttctgcgaa ttgttccaag
     2461 cgttcaatat cttcttcctc ggcagaaaga tcaactttaa cacactctga acctttttct
     2521 gctcctgttg acacaaagac acggtcaaag tcatcaacag ccttacaaaa ttcatcgtag
     2581 aaggtatctc ctgagccgac cactccgtag attttgccat tcaagttgag atctgctagg
     2641 tcttcgtaga agtccatcat ctcatctggc aattcaccat caccataagt ataggtcgca
     2701 acgatagcga tgtctgcttc caagaagtct gaagcgtcaa cagttgtaca ttcatcaaca
     2761 tcaacatcca agcccaagtc acgtaatttg tctgctacaa tatctgcaat ttcttcggta
     2821 ttaccggtca tactggcaaa tacaattttt gctaatgcca tatcgtcctc ctcaatttat
     2881 ctttctccat tatatcacat ctttttcatt ttaaaaataa aaattcttgt gctacaatga
     2941 aatgagaaag aattgaggtt atttatggag atttgccaac aaattttaga aaaaattaaa
     3001 gaatacgaca ccattatcat tcatcgtcat atgaaaccag accctgatgc cttgggaagt
     3061 caggtgggat tgaaagcctt gctagaacat catttcccag aaaaaaccat caaagccgtc
     3121 ggttttgatg aaccaactct tacttggatg gctgagatgg atcttgttga agatagagcc
     3181 taccaaggcg cacttgtcat cgtctgtgat acagctaata ctgctcgtat cgatgataag
     3241 cgctatagtc aaggtgattt tctcattaag attgaccacc atccaaatga tgatgtatac
     3301 ggtgacctgt cttgggtcga tactagttca agtagcgcta gcgagatgat taccctattt
     3361 gcccaaacaa cccaactagc cttggcagat cgcgatgctg agttgctctt tgcaggaatt
     3421 gtcggtgata caggtcgctt cctctaccct tctaccactg cacggactct tcgcctggct
     3481 gcttatttga gagaacataa ctttgacttt gcggctctca ctcgcaaaat ggacactatg
     3541 agctacaaaa ttgctaaact gcaaggctac atctacgacc atctggaagt ggatgaaaat
     3601 ggtgctgctc gcgttatcct gagtcagaaa atcttgaaac aatacaatat aaccgatgct
     3661 gaaactgcgg ccattgtagg tgcacctgga cgcattgaca gagtgagtct ctggggaatt
     3721 tttgtcgaac aggctgatgg ccactaccga gttcgcttac gcagtaaagt ccatcctatc
     3781 aatgaaattg ccaaggagca tgatggtgga ggccaccctc tagcaagtgg tgctaattcc
     3841 tatagcctag aagaaaacga aatcatctac caaaagttaa aaaacttgct taaaaactga
     3901 taaaatactt gccaaacttt tcagaatctg atagactagt atagtaacaa tctatggctc
     3961 gcaaagagac catggcagaa aggaaatatt gcaaaatgaa aaaagatatc catccagaat
     4021 atcgcccagt tgtcttcatg gacacaacta ctggttacca attccttagc ggttcaacaa
     4081 aacgctctaa cgaaacagtt gagttcgaag gcgaaactta cccattgatc cgtgtggaaa
     4141 tttcatcaga ctcacaccca ttctacactg gacgtcaaaa gttcactcaa gcagatggac
     4201 gcgtggatcg tttcaacaaa aaatacggtc tcaaataatg ataagagaac agttttggct
     4261 gttctttttt gtttcttgaa atcaactgct gttttcatgt tccagactca tctgtaggtt
     4321 cgatttccat gctactaggc aggaaggaaa tagctgtttc aacacgtcca taatgagcta
     4381 tactattgtc acgaaccaca ctttcattga tggtccaagt ggaattcatt ttcttaaaag
     4441 cttctcggac tttttccaaa tctttggagg caatggcctg ctctaaggtt tcaaaacgag
     4501 gacttatact catctgcttt caaaaagcat tctagtccat ctccgattac cgatggactt
     4561 tatcacctcc ttctccagtc cttgtatgac atcttgaagt tgattcatga catcttccaa
     4621 agttcgaaag gctttattct taaatccacg tttacgaatc tctttccaca cttgttcaat
     4681 gggttcatct ctggtgtgta tggaggaata aaggtaaaat caatattagt cggaatattt
     4741 aaggtacttg atttatgcca tatagcattg tccataacga gtaaaaggat aagcttgtga
     4801 aagctcttct aaaaaggcgt tcatccacac tcctttttat aaacctgaaa taaggcatca
     4861 attgtaacaa attctcctgc ctctgtagcc ttcaaatgac gggcaagaaa ggctttctct
     4921 tcctcaactg tcatatatgc atggttacga ccaccacgtg tttcttgaag gagagagtcg
     4981 agtccgaact cctcatattt ttttacgttt cgccaaatcg ttgtttgatt acagtctaaa
     5041 agctctataa tctctttata agatttgccc atcagacgaa atatagtaga ttgaaactag
     5101 aatagtacac ctctacttct aaaacattgt tagaaatcga tttgtcctgt tcttgtttca
     5161 ttt
//
LOCUS       DAVKBK010000085         5124 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVKBK010000085 DAVKBK010000000
VERSION     DAVKBK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.085"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..736
                     /locus_tag="VWX69_001889"
     CDS             <1..736
                     /locus_tag="VWX69_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9193175.1"
                     /translation="VSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGF
                     YNVNKGSIKIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVM
                     RALKLAGCDLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASA
                     SIDPDNEFELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMS
                     KDTRYKSLQEMFNSANEWRVSNERVL"
     gene            720..2441
                     /locus_tag="VWX69_001890"
     CDS             720..2441
                     /locus_tag="VWX69_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9193176.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            2452..3036
                     /locus_tag="VWX69_001891"
     CDS             2452..3036
                     /locus_tag="VWX69_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9193177.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            3036..3731
                     /locus_tag="VWX69_001892"
     CDS             3036..3731
                     /locus_tag="VWX69_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9193178.1"
                     /translation="MSTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGISF
                     KNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            3719..5083
                     /locus_tag="VWX69_001893"
     CDS             3719..5083
                     /locus_tag="VWX69_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9193179.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSINVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFIFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         1894 a          651 c          959 g         1620 t
ORIGIN      
        1 tgttagcttt gcttataatg ataaagctgt cattgaaaat ttatccttta atttagaaga
       61 aggaaagtcc tacgcacttg tcggttcatc tggatcaggc aaatcaacag tagcaaaact
      121 tatatcaggt ttttacaatg ttaataaagg aagcataaag ataggcggga tagcaataag
      181 tgaatattct gacgaagcct taattaaagc catttccttt gtttttcaag attcaaaatt
      241 attcaagaag agcatttatg ataatgtagc tttagctaat aaagatgcga cgaaagatga
      301 cgttatgaga gccttaaaat tagcaggatg cgatttaata ttagacaaat tcccagaaag
      361 agaaaataca atcataggct caaaaggtgt ttatttatcc ggtggagaaa aacaaagaat
      421 tgcaattgct agagcaattt taaaggattc caaaattatt attatggatg aagcatcagc
      481 atctattgac ccagataacg agtttgaatt gcaaaaagct tttaaaaatc ttatgaagga
      541 taaaacagtt atcatgattg cacacaggct atctacaatt aaagaccttg atgaaattat
      601 tgtcatggat agtggaaaaa ttatagaaag agggtctgac aaagaattaa tgtcaaaaga
      661 tacaaggtat aagagcctgc aagagatgtt taacagtgcg aatgaatgga gggtttcaaa
      721 tgaaagagtt ttataaaaaa agatttgctc ttacagatgg aggagcaaga aatttaagta
      781 aagcaacact ggcttcattt ttcgtttatt gtataaacat gcttcctgcc atattactta
      841 tgatttttgc tcaggaagtt ttggaaaata tgggcaaaag caatggcttt tatatagtat
      901 tctcagtttt gactttgata gcaatgtata ttttgctttc tatcgaatac gataaattat
      961 ataacacaac ctatcaagaa agtgcagatt taagaataag gacagcggag aatttatcaa
     1021 aattacctct atcttacttt tctaaacatg acatttccga catttcacaa acaatcatgg
     1081 ctgatattga aggcatagag catgcaatga gccactcaat accaaaggtg ggcggcatgg
     1141 tactgttttt cccattaata tctgtaatga tgctagcggg caatgtcaag atgggtttag
     1201 ctgtaattat tccatctatt ttaagcttta tatttatacc tttatctaaa aaatatcagg
     1261 ttaatggaca gaatagatat tatgatgtct taagaaaaaa ctcagaaagc tttcaagaaa
     1321 atatcgaaat gcaaatggag attaaagcat ataatttatc gaaggatatt aaagatgact
     1381 tatataaaaa aatggaagat agtgagagag tacacttaaa ggcagaagta actacaattt
     1441 taactttgtc tatatcttca atatttagct ttatatctct tgctgttgtg atatttgtcg
     1501 gcgtaaatct aattattaat aaagagataa attctctcta ccttatagga tatttactag
     1561 ctgctatgaa gataaaagac tctttagatg catctaaaga gggcttgatg gaaatatttt
     1621 atttatcgcc caaaatagaa agattaaaag aaattcaaaa tcaagattta caagaaggcg
     1681 atgactatag cttaaaaaaa tttgatattg atctaaaaga tgttgagttt gcctacaata
     1741 aagacgcaaa agttttaaat ggtgtaagtt ttaaagctaa gcagggagag gtcactgctt
     1801 tggtaggtgc aagtggctgc ggtaaaacaa ctatcttgaa acttatatca agactttatg
     1861 attatgacaa gggacaaatc ttaatcgatg gcaaagatat aaaagaaata tcaacagaat
     1921 ctctttttga taaggtctct atagttttcc aagatgtggt tctctttaat caaagcatta
     1981 tggaaaatat tagaatcgga aagcaagatg caagtgacga agaggttaaa agagcagcaa
     2041 aacttgcaaa ttgcacagat tttatagaaa aaatggataa aggtttcgat acagttattg
     2101 gtgagaacgg agctgagcta tcaggaggag aaagacaaag attatcaata gccagagcct
     2161 tcttaaaaga tgcgccgata ttgatcttag atgagataac agcaagcctt gatgttaaca
     2221 acgagaaaaa gattcaagag tctttaaata atttagttaa agataaaact gttgtaatca
     2281 tttcacatag aatgaaatcc atagaaaatg cagacaagat agtagttctt caaaacggaa
     2341 gagtagaaag cgaaggtaag catgaagagc ttttacaaaa atcaaaaatt tacaaaaatt
     2401 taatagaaaa gacaaaaatg gcagaagaat ttatttatta ggaggactac aatggataat
     2461 aaaaaattaa aagtaaaaga tttagtaagt atcggtgttt ttggcgtaat ttattttgcc
     2521 ttcatgtttg gagttggtat gatgggcttg attccaatat tgttcttaat atacccgaca
     2581 gtattagcca tagttgcagg aactgttgtt atgttattta tggctaaggt tcaaaagcca
     2641 tgggcactat ttatatttgg tatgatatca ccacttgtga tgtttgcagc tggtcatacc
     2701 tacgtagttg tggttttatc acttatagta atgataatag cagaattaat tagaaagatt
     2761 ggtaattata attcatttaa atacaatatg ctttcttatg caatcttcag cacatggata
     2821 tgtagctctt taatgcaaat gcttttagca aaagaaaaat atatggagtg gtctttgatg
     2881 acgatgggaa aagattatgt tgatgtatta gaaaagttaa taacttatcc tcacatggct
     2941 ttagtagcct taggtgcttt cttaggagga attcttggag catatatagg caaggctcta
     3001 ttgaaaaaac actttgaaaa agcaggcatt gtataatgtc tactttttct tcaaatgctc
     3061 cctttaatcc caatccgatc tctaagatat tagtcgtatt tatcacaggc ttaactgtta
     3121 tgcatagcat aaacatccgt tttgagctgg caattgtttg tcttattggt attttgcttt
     3181 atttgaatgg atacaaaaaa acacttttca aatggattat attgtgtggg atactttact
     3241 ccttgcctaa ttttatggtg ttatctgaat taaaccctat agttaagatg tttttgagta
     3301 tacctattgt tattagaatg tttattttac catttatggc agcaagcttt atgataaaga
     3361 cctcggatgt aggcgcaata atttcatcga tggataagct taagatttca aagaatgtat
     3421 ccatacctat tgcggttatg tttagattct tcccatcttt taaggaggag aagaaaaaca
     3481 tcaaaatggc tatgagagta agagggataa gttttaaaaa cccagtcaaa tatcttgaat
     3541 atgtttctat gccactactc attatatcat ctaatatatc agatgacatt gcaaaagcgg
     3601 cagaaacaaa ggcaatagaa aatccaattg ccaagaccag atacattcgc gtaaagatac
     3661 agctaattga ttttgtttat gttttagcgg ttgctggact tattgtggga ggcttaatat
     3721 ggttgaaata aaaaatttaa gtcttgatta tggtgaagag catatattag atgatatatc
     3781 actatccata gccgagggag agtgcgtgct atttacagga aaaagtggaa atggtaagtc
     3841 atctttaata aattcaatca atggactagc tgtaaggtat gataacgcaa agacaaaggg
     3901 cgaaataatt attgatggta agaatataaa aaatttggaa ctttatcaaa tctcaatgct
     3961 tgtttcaact gtttttcaaa atcctaagac atattttttt aatgtcaata cgacattaga
     4021 attattattt tatttggaaa atatcggtct tgcaagagaa gagatggaca ggcgtttgaa
     4081 ggatatgctt aagatattcc cgataaaaaa tcttttgaac agaaatatat ttaatctatc
     4141 cggcggtgaa aaacaaattc tttgcattgc agcttcttat atagcaggta caaagattat
     4201 agttatggat gagccttcat cgaatttaga tattaaaagc ataaatgttt tggcaaagat
     4261 gctaaagata ttaaaagaga aaggcataag cataattgtt gcagagcata gaatttatta
     4321 tttgatggac atagttgacc gtgtattttt aatagataaa ggaaagctta aaaaaactta
     4381 tactagaagt gaatttttaa agctagataa aaatgaatta aatgctttaa gtttaagaga
     4441 taaagaatta agtaaattaa aagttcctta tttaaaagaa ggtggagagt atcagataaa
     4501 aaatcttagc tacaaattta ctgatgatga gtgtttaagc ttaaaagata tttcattcaa
     4561 gcttgggaaa atttatggca taataggatc caacggacga ggaaaatcaa cgcttttaag
     4621 atgtttaata ggtcttgaga aaaaatcaaa agaagaaatt tattttaagg gagagaagct
     4681 atctaaaaaa gaaagactca aaaactcttc acttgttatg caagatgtaa atcatcaatt
     4741 attcacagat gaagtattca acgagcttag attaggagta aagaattttg atgaagaaaa
     4801 ggcgaaaatc attttaaaag atttaggcct ggacgaattt attgaaaggc atccgatgag
     4861 tttatcagga gggcaaaagc aaaggcttgc aatagcatct gttatgtgca agaattctcc
     4921 atttatcttt tttgacgaac cttcaagtgg tatggattat tccaatatga taaaaatatc
     4981 tgaactgatt aataagtata aaaccatgga taaaataatt tttattgttt cccatgatat
     5041 agaattttta aatgaagtgg cagatgaaat ttttgaattg taaaatagag tctgttaaac
     5101 atgtctatag aactagtaaa ttgt
//
LOCUS       DAVKBK010000086         4777 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVKBK010000086 DAVKBK010000000
VERSION     DAVKBK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.086"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            59..763
                     /locus_tag="VWX69_001894"
     CDS             59..763
                     /locus_tag="VWX69_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU9193180.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     misc_feature    822..909
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            945..1259
                     /gene="rplU"
                     /locus_tag="VWX69_001895"
     CDS             945..1259
                     /gene="rplU"
                     /locus_tag="VWX69_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU9193181.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            1275..1619
                     /locus_tag="VWX69_001896"
     CDS             1275..1619
                     /locus_tag="VWX69_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU9193182.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            1636..1929
                     /gene="rpmA"
                     /locus_tag="VWX69_001897"
     CDS             1636..1929
                     /gene="rpmA"
                     /locus_tag="VWX69_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU9193183.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(2240..2445)
                     /locus_tag="VWX69_001898"
                     /pseudo
     CDS             complement(2240..2445)
                     /locus_tag="VWX69_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            2882..3799
                     /locus_tag="VWX69_001899"
     CDS             2882..3799
                     /locus_tag="VWX69_001899"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU9193184.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            complement(3892..4740)
                     /locus_tag="VWX69_001900"
     CDS             complement(3892..4740)
                     /locus_tag="VWX69_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9193185.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
BASE COUNT         1515 a          819 c          974 g         1469 t
ORIGIN      
        1 atggtagcct acgatttttt agaaagaaaa tggtacaata tttctaagag aaaatacaat
       61 gggaggtaaa atgaggttat tacctataag aaaaatatca cgtcagtcta aaaggttagc
      121 actttttttg acgttttgtg ctggatatgt ggatgcttac acttttattg ttcgcgggaa
      181 tacccttgta gctggacaaa ctggaaatgt tgtctttctt tcagtagaat taattaaaaa
      241 taatgtttcg gatgttaggg acaaggttct caccttgcta gcgtttatga tgggagtctt
      301 tttattaacg atttataagg aaaaattgag aattgtgaaa aaacctattc tgtccttgat
      361 tcccttggca atcttatcaa tcattattgc ttttgtgccg caaactgtgg ataatatcta
      421 tctagtgccg cccttggcct tctgtatggg actggtgaca actgcttttg gagaagtgtc
      481 gggtattgcc tataataacg cttttatgac agggaatatc aaacggacca tgctggcttt
      541 tggagattat ttccgaacca agcacactcc ttttttgcgt gaaggattca tatttgttag
      601 cctgcttagt agttttgtcc ttggcgttgt cttttcagcc tatttgacga ttttctatca
      661 tgaaaagacc attcttggtg ttcctattat gatgagcgtt ttttacctca gcatgctttt
      721 tgcctcttgg cagaaaaaag taaaagaaaa agcttcattt taggtgttat tacttgtaag
      781 aaaataggag atatgctata cttgaagagt tgactatgca cgatcctgtg caaccgcacg
      841 aacatcgttg cttgattatt caagtttaag tggttcgtcc cacgatgcta ggcgagtctt
      901 cacaaaaaat cggggaaacc cataaaaatc ataggaggtg cataatgagc acatacgcaa
      961 ttatcaaaac tggcggaaaa caagttaaag ttgaagttgg tcaagcagtt tacgttgaaa
     1021 aattgaacgt tgaagctggt caagaagtta cttttaacga agttgttctt gttggtggtg
     1081 aaaacactgt tgtcggaact ccacttgttg ctggagctac tgtagttgga actgttgaaa
     1141 aacaaggaaa acaaaagaaa gtggttactt acaagtacaa acctaaaaaa ggtagccacc
     1201 gtaaacaagg tcaccgtcaa ccatatacaa aagttgtcat caacgcaatc aacgcttaat
     1261 tttaaggaga acacatgata caggcagtct ttgagagagc cgaagatggc gagctgagga
     1321 gtgcggaaat tactggacac gccgagagtg gcgaatacgg cttagatgtc gtgtgtgcat
     1381 cggtttctac gcttgccatt aactttatca attctattga gaaatttgca ggctatgaac
     1441 caatcctaga attaaacgaa gatgaaggtg gctatctgat ggttgaaata ccaaaagatc
     1501 ttccttcaca ccagagagaa atgacccagt tattctttga atcatttttc ttaggtatgg
     1561 caaacttatc ggagaactat tctgagttcg tccaaaccag agttatcaca gaaaactaac
     1621 acggaggaaa acattatgtt aaaaatgact cttaacaact tgcaactttt cgcccacaaa
     1681 aaaggtggag gttctacatc aaacggacgt gattcacaag caaaacgtct tggagctaaa
     1741 gcagctgacg gacaaactgt aacaggtgga tcaatccttt accgtcaacg tggtacacac
     1801 atctatccag gtgtaaacgt tggtcgtggt ggagacgata ctttgttcgc taaagttgaa
     1861 ggcgtagtac gctttgaacg taaaggacgc gataaaaaac aagtttctgt ttacccaatc
     1921 gcaaaataaa aaggttcatt gaacctttta tcccgaacct tgaaatgtaa aggtgaggaa
     1981 gctagaaaca gcttaaaata aggctttccg agttttcgga gagcctgttt ttttattttg
     2041 atacccatac tttttaatat gtatagtgga ttgatactct tcgaaaatca aattcaaacc
     2101 acgtcaattt caccttgccg tactcaagta cagcctgcgg ctaacttcct agtttgcact
     2161 ttaattttca ttgagtatga atctggaata gaacactgtt aaaaattgat atgagtttcc
     2221 tactcgattt cttcagattt tatttcaatt gactataaga actgctatct ggtttcaaat
     2281 attggcttgt cgtcccttca cttgtctgaa tggtttgagc cgttccttct gataagggaa
     2341 aagatattct ttagctgaaa cggtctgaga atccaagcta acagatggag agaaaaatag
     2401 cccagtctga agcacactag atgggagttg ttggaaagca gtcatctagt ttttctttgc
     2461 tgttttggct tttttctttg tcatcaggga aagtgacttg cttcaaatca gggagtttag
     2521 gaaattcttc aaacatcttg cccaagttgt ctcattttgt aaattttaca gccataggtg
     2581 tacctcgatt ctaaattcta cctttttggc accaattagt aatttaaagt tctcaggagt
     2641 tagttgcatt gctttttcat acataacata gtatgacact ttatggttac cgaacaagtc
     2701 taatcactcc ttgcaaaatt ttgaagatgt cctacaagtt tttgagaaga atattgcaaa
     2761 gttcatagtt aagcaacgat agaataaagt gctttttgaa aacaggtaca cttcatgtga
     2821 aaaaaacaac atttcagatt ttctgttcca gaaatagcta tcgctatgat ataattattt
     2881 tatgattatt actattccta taaaaaacca aaaagatatt ggcacaccat ctgattcagt
     2941 cgttgttctc ggctattttg atggcataca taaggggcat caagaattat ttcgtgttgc
     3001 caacaaggct gcgagaaagg atttattgcc tatcgtcgtt atgaccttta atgaatctcc
     3061 aaagatcgct ttagagcctt atcatccaga tttgtttttg catattttga accctgctga
     3121 acgtgaaaga aaattaaagc gcgaaggtgt agaagaatta tatctccttg attttagtag
     3181 tcaattcgct agtctcactg cacaagaatt ctttgcaact tatatcaagg ctatgaatgc
     3241 caaaattatt gttgcaggtt ttgattatac atttggttct gacaaaaaaa cagcagaaga
     3301 tttaaaggat tactttgatg gagaagttat cattgttcca cctgtagaag atgagaaagg
     3361 aaagattagt tcaactcgta tccgtcaagc tattttagat ggaaatgtga aagaagcagg
     3421 aaaacttttg ggggcaccgc ttccatcaag aggtatggtg gttcatggta atgctcgtgg
     3481 tcgtacaatt ggttatccga cagcgaattt agtgctttta gaccgtactt atatgccagc
     3541 agatggcgtt tatgtcgttg atgttgagat tcaaagacag aagtatcgtg ctatggctag
     3601 tgtcgggaaa aatgtgacct ttgatggaga agaagcacgt tttgaagtca atatttttga
     3661 ttttaatcaa gatatttatg gggaaaccgt catggtttat tggcttgatc gcattcgtga
     3721 tatgaccaaa tttgactcag ttgaccaatt agtggatcag ttaaaggctg atgaagaagt
     3781 aactcggaat tggtcttaag agcttgagta aataaaacaa aaaagaggtt gtctgtaacc
     3841 caaaagatag atgatttagt ctaacttttg aggtcacgac attacctctt tttattcttt
     3901 ttcaaaggtg aagccttctc ctaggatttc atgggcttct gtaatagtta taaaggcttg
     3961 aggatcgatt cgatgaatca tttccttcgt tttcacaatt tcatttcttc cgacaataca
     4021 gtagatgatt ttcaaatttt ctttactata gtagccttga ccagaaataa aagtaacacc
     4081 tcttccgagg tcatcattaa tcgccttagc aagttggtca ggacgttttg tgataatcat
     4141 aaagcctttg ccggcatatc ctccttcacc aatcaaatca ataacacgag aaacaataaa
     4201 atcaaacaaa agcgtgtagg aaaccaatct caaatccttg aagattagga gaatcaacat
     4261 gagaatacaa aaatctaaga taaagagcag ttttcctatg gatatatgag tgtatttgtt
     4321 gagaatacga gctagaatat cagttccgcc agttgtacct ccagcattaa aaataattcc
     4381 aaggccaatt cccaatagga ttcccgctat aagggctgtg attagtaaat caccttgaag
     4441 atcaatatga aggggaatat gctcaaaaaa agctaaccag gcggacaaag ctaaggttcc
     4501 tagtaaacta gaatagaggg atttggctcc aaagatcttc caagctagga tgaaaagggg
     4561 aatattaatc agcaggttca tgagggaaac agggatttta aaaagataaa aggtgatgag
     4621 ggtaatgcct gtcgcccctc cttcaaagag atgatgggga actacaaaat aagtcagtcc
     4681 aaaagcataa atagcagcac ctagtaaaat ggtaaaaatg gggtaaattt ttttaatcat
     4741 aggacacctc ttttcttata agttgattat atcaaat
//
LOCUS       DAVKBK010000087         4618 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVKBK010000087 DAVKBK010000000
VERSION     DAVKBK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4618
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.087"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            96..329
                     /locus_tag="VWX69_001901"
     CDS             96..329
                     /locus_tag="VWX69_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU9193186.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            329..1663
                     /locus_tag="VWX69_001902"
     CDS             329..1663
                     /locus_tag="VWX69_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU9193187.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            1673..1927
                     /locus_tag="VWX69_001903"
     CDS             1673..1927
                     /locus_tag="VWX69_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU9193188.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            2023..2418
                     /locus_tag="VWX69_001904"
     CDS             2023..2418
                     /locus_tag="VWX69_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9193189.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            2918..3280
                     /locus_tag="VWX69_001905"
     CDS             2918..3280
                     /locus_tag="VWX69_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193190.1"
                     /translation="MLAMEQAGFISHQEKLERLGVHYEISERTQTPILDACPLVLDCR
                     VDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKR
                     VDMKGSFIKKARKKDGKN"
     gene            3267..3824
                     /locus_tag="VWX69_001906"
     CDS             3267..3824
                     /locus_tag="VWX69_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9193191.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            3826..>4618
                     /locus_tag="VWX69_001907"
     CDS             3826..>4618
                     /locus_tag="VWX69_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEU9193192.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLES"
BASE COUNT         1428 a          824 c         1060 g         1306 t
ORIGIN      
        1 acaacctcaa agcactgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt attagaacat acaatggagg tcgtcatgga caatatcatc gatgtgtcaa
      121 ttcctgttgc agaagtggtg gacaagcatc cagaagtctt ggaaattcta gtggagttgg
      181 gttttaaacc ccttgccaat cccttaatgc gcaatacagt tggtcgtaaa gtatcactta
      241 aacaaggttc taagctagca ggaactccta tggacaagat tgtacgcaca ctggaagcga
      301 atggctacga agtgattgga ttagactaat ggcagatgaa cggattcatg tcctacggga
      361 tattttatta gaattgcata atggcgcctc tcctgagtcg gttcaggagc gttttgatgc
      421 gacctttgcg ggtgtctcag ccattgagat ttcccttatg gagcacgagc tgatgaactc
      481 agactcaggt gtcacctttg aagatgttat ggaactctgt gatgtccatg ccaatctttt
      541 taaaaatgct atcaaaggtg tcgaagtttc agatactgag catccaggtc acccagttcg
      601 tgtcttcaaa gaagaaaatc tggctctccg tgcggccttg attcgcattc gtagattgtt
      661 agatacctat gagtctatgg aagacgagga aatgctggcg gagatgcgta agggtttggt
      721 gcgtcagatg ggacttgtgg gtcaatttga catccattac caacgtaagg aagaactctt
      781 ctttcctatc atggagcgct atggacacga ttcacctccc aaagttatgt ggggagtgga
      841 tgatcagatt agggaactct ttcaaacagc tctaacgaca gccaagtcac taccagaagt
      901 gtcaattagc agtgtaaagg aagcttttga agcttttgcg acagagtttg aaagtatgat
      961 tttcaaggaa gagtccatcc tcctcatgat tctccttgag tcttttactc aggatgactg
     1021 gcttcagatt gcggaggaga gcgatgccta tggctatgcc atcatccgtc cgtcagagaa
     1081 atgggtgcca gaacgacaga gctttattga ggaaaagatt gcagaggagc ctgtacagct
     1141 agatacggca gaaggtcaag ttcaacaagt catagatacg ccagaaggcc attttaccat
     1201 tacctttacc cctaaggaaa aggaagctgt gctggaccgc catagtcaac aggcttttgg
     1261 taatggctat ctttcagtcg agcaggccaa tctcatcctc aatcatctcc ctatggagat
     1321 tacctttgtc aataaagaag atattttcca gtattacaat gacaatacgc cagctgatga
     1381 gatgattttc aaacggacgc cgtcccaagt cgggcgcaat gtcgaactct gtcatccgcc
     1441 taagtatttg gacaaggtca aggctatcat gaagggactt cgtgagggga ccaaggacaa
     1501 gtatgaaatg tggttcaagt ctgagtcgcg aggcaagttt gtccacatca cctatgctgc
     1561 agtacacgat gaaaacggag aattccaagg tgtactggaa tacgttcagg atatccagcc
     1621 ctaccgtgag attgatacgg actatttccg tggattagaa taaggagaaa aaatgagtta
     1681 cgaacaagaa tttatgaagg aatttgaagc ttgggtcaat acccaaatca tgattaacga
     1741 catggcgcac aaggaaagcc aaaaagttta cgaagaagac caggacgagc gtgccaaaga
     1801 tgccatgatt cgctacgaga gtcgcttgga tgcttatcag ttcttgcttg gtaagtttga
     1861 aaacttcaaa gtaggcaagg gattccatga tttgccagaa ggcttgtttg gtgagcgaaa
     1921 ttattaaacg agaaagattc ttgatttttc actaaaatct tgatagaatg tttatgttaa
     1981 atccttgtca gagcagggat tttttattga aaggatttta tcatgtcaaa gaaactcaat
     2041 cgtaaaaaac aattacgaaa tggcctccgt cgcgcaggtg ccttttcaag tactgtgact
     2101 aaggttgtag atgagacaaa aaaagtcgtg aagcgtgcag aacagtcagc aagcgcagct
     2161 ggtaaggctg tttctaaaaa agttgaacaa gcagtagaag ctaccaaaga gcaagctcaa
     2221 aaagtagcta attctgtaga agattttgca gcaaatttgg gtggacttcc acttgatcgt
     2281 gccaagactt tctatgatga aggaatcaag tctgcttcag atttcaaaaa ctggactgaa
     2341 aaagaactcc ttgacttgaa aggaatcggc ccagctacca tcaagaaatt gaaagaaaat
     2401 ggcatcaagt tcaagtaatt tttcttgagc cttgcatttc cgaaaaaatc ttgctacaat
     2461 agagccatta gaggtgtttt gaatcccaca ttttacagaa agtggcggcg ctgagaagtc
     2521 cacaaatgtg tcaaaactgg ttgctaatgg atgaaaaatt gaaataaaag tgtctttttg
     2581 ctttaaagac gagagttgcg ggcaactgcc cgaaattggg tggtaccgcg gataaacaca
     2641 ttcgtccctg tcatgtagat ggcagggctt ttcttttacg tcttagtcaa agggggttgt
     2701 tatgaagcaa tcttttaaca caagtaaact atattatggt tttcctgttt ttattttagg
     2761 atatcaagat tagaattttg gctataacat cacgacctgt agttcctctt atagtctagg
     2821 agattgggtt gtgattggag tcgttgcgag agagaatgcc gcagagtaga tcaaacagta
     2881 tcaaaaattt actgtgaata tttctgatga aacttctatg cttgcgatgg agcaggctgg
     2941 ttttatcagt catcaggaga aattggaacg tttgggagtg cattatgaaa tttctgaacg
     3001 aactcagact cctattttag acgcctgtcc acttgtttta gattgtcggg tagataggat
     3061 tgttgaggaa gacggtattt gccacatctt tgccaagatt cttgagcgac ttgttgcccc
     3121 agaactcctg gatgaaaagg gacattttaa aaatcaactg tttgccccaa cctatttcat
     3181 gggagatgga tatcagcgcg tttatcgcta tctggacaag cgtgtagata tgaagggcag
     3241 tttcatcaaa aaagcgagga agaaggatgg caagaactga gctgccagat aaaatcgaaa
     3301 cagaacgtct cgttttacga gtccgtactg tggcggatgc tgaggatatc tttgactatg
     3361 ctagtttgcc agaggtcgcc tatccagcag gttttcctcc agtcaagacc ttggaagatg
     3421 agatttatta tctggagcac attcttccgg agcgtaatca aaaggaaaat ctcccagcag
     3481 gctacgggat tgtcgtcaaa ggaacggata agatcgttgg ctctatctat ttcaaccatc
     3541 gccatgaaga tgatgtgatg gaaatcggct ataccttaca ctcagactat tgggggcgag
     3601 gttatgtgcc agaagctgcg cgtgccttga ttgacttagc ctttaaagat ttgggtcttc
     3661 acaagattga actaacttgc tttggatata accttcaaag tcaacgagtc gcggaaaagc
     3721 ttggctttac cctcgaagct cgcataagag accgaaagga tgttcaagga aaccgctgtg
     3781 acagtctgat atatggcttg ctgaagagcg agtgggagga ataagatgag cgatgtaaaa
     3841 gaggaagtaa gctctctatc tgagaagcag ttacgccaaa ttgatgttga gtatgctgaa
     3901 ttaaatgata gtgatattat cgagcgatta gcttatttag aaattaacaa caatgaaaaa
     3961 cgtattgtca tctctgatat tgaaccaacc aaggaaataa tgtcagtctc ggaccaaatt
     4021 tttgagattc aaaagaattt tcaaaaaatc aagaatatgt tcgaattgtt tatttcagat
     4081 gtctcggatt ttttaagtat taaaaataaa cttgagtcaa aggaattaga aattgaagag
     4141 gcagatgtaa atcgtttcat gattcattta ttatccagtg gaaaattgtt tgtcgatttt
     4201 aacgaaaacc aaattaaaca aaaatattcc aaagatagtg aggagtttga ttgtatacat
     4261 ggttttgcaa gctatcagta tgataccaat tttgcttatc gattttgcca ttctttgaga
     4321 aattattcgc aacatactga cttaccaata aatgaggtaa aagctgttag cccagatgat
     4381 gagactgtta taatagattt ctatattgat ttagattatc ttttaaattc caactttaaa
     4441 tggaaaaaat tgaaagggga gttgataaaa ctaaaccaag aaacatctaa gattgacgct
     4501 atagctctag tgaaagaata ctttaatgct cttacagagc tctatggtaa ttataataag
     4561 ttgtttttaa agttaaacca taatacatta gtagatatta aatcaaagtt ggaatcat
//
LOCUS       DAVKBK010000088         4481 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVKBK010000088 DAVKBK010000000
VERSION     DAVKBK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.088"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(130..1116)
                     /locus_tag="VWX69_001908"
     CDS             complement(130..1116)
                     /locus_tag="VWX69_001908"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU9193193.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            1310..3778
                     /gene="gyrA"
                     /locus_tag="VWX69_001909"
     CDS             1310..3778
                     /gene="gyrA"
                     /locus_tag="VWX69_001909"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU9193194.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINAESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            3778..>4481
                     /gene="srtA"
                     /locus_tag="VWX69_001910"
     CDS             3778..>4481
                     /gene="srtA"
                     /locus_tag="VWX69_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU9193195.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDE"
BASE COUNT         1366 a          792 c         1012 g         1311 t
ORIGIN      
        1 aatttaaagc attttataac aacgttttag agtaatgggg tgctatttca acttcaacct
       61 actataatac agaaaaaaat acagaaaaaa acaactccct gatgattcaa ggagttgtct
      121 atagttaaat tagtttttag aagcttcttg gaattctgga tttttccatg cttcgtcaat
      181 aatagcttgc aattctttag cagatgcttg cattttttga gtttctgcat cgttcaatgg
      241 aatgtttact ggacgaacga taccatgtgc accaacaaca gctggttgac cgataaagac
      301 attctcaact ccgtattgac cttcttggaa tactgaaagt ggaagtactg cgttttcatc
      361 gtcaaggatt gctttagtga tacgagcaag ggctactgcg ataccgtagt atgttgcacc
      421 ttttttgttg atgattgtgt aggctgcatc acgaacacct tcgaacaatt caatcaattc
      481 agcttcttga acattttgag tgtctttaag gaattcttca aggtttacac cagcgatgtt
      541 agcgtgtgac caaacagcga actcagagtc accgtgttca cccatgatgt aggcgtgcac
      601 tgaacgagca tccacatcca atttttcagc aagtgcttga cggaaacgag ctgagtcaag
      661 tgaagtacct gaaccgataa cgcgttcttt agggaaacca gagaatttcc aagttgagta
      721 agtcaaaacg tcaactgggt tagcagcaac aaggaagata cctttgaaac cagattcaac
      781 aacttgagtt acgattgatt tgttgatagc aaggttttta cctacaaggt caagacgagt
      841 ttcacctggt ttttgaggtg cacctgcagt gatcacaaca aggtcagcgt ctgcacagtc
      901 agagtattga gctgcataga tttttttagg tgaagtgaag gcaagggcgt gactaaggtc
      961 aagcgcatca ccaacagctt tttcatgcaa ttgtggaatt tcgataattc caagctcttg
     1021 tgcaattcct tggttaacaa gtgcaaaagc gtaagatgaa cctacagcac catcaccgac
     1081 aaggataact tttttgtgtt gtttagttga agtcattgtt ttaaacatct ccttaatttt
     1141 attaggggat tttccctaga caacttcatt ctatcacttt taaaaaactt tgtcacgaat
     1201 atgccttata gttctcgatg taaacgtttt agtggtttag aggctgaaat agatgggaat
     1261 ttatggtata atgttgttac ttactaattg tgaaatgagg catttattaa tgcaggataa
     1321 aaatttagtg aatgtcaatc tgacaaagga gatgaaggca agttttatcg actacgccat
     1381 gagtgttatc gtagcgcgag ctcttcctga tgttcgagat ggcttaaaac ctgttcaccg
     1441 tcgcattctc tacggaatga atgaattggg tgtgacccca gacaaacccc ataaaaaatc
     1501 tgctcgtatt acaggggatg tcatgggtaa atatcaccca cacggggatt cctctattta
     1561 tgaagccatg gtccgtatgg ctcaatggtg gagctaccgt tacatgcttg tagatggtca
     1621 tgggaatttt ggttccatgg atggagatag tgctgccgct caacgttata ccgaggcacg
     1681 tatgagcaag attgctctgg aaatgcttcg tgatatcaac aaaaatacag ttgatttcgt
     1741 tgataactat gatgccaatg aacgggaacc cttggtcttg ccagcgcgtt ttccaaacct
     1801 tttggttaat ggagcaactg gtatcgcggt tgggatggca accaatattc cacctcataa
     1861 tctgggtgaa accattgatg cagtgaagtt ggtcatggat aatcctgaag tgactaccaa
     1921 ggacttgatg gaagtcttgc ctggaccaga ttttccaact ggtgctcttg tcatggggaa
     1981 atcaggtatc cataaggctt atgaaacagg taaaggttcg attgtcctac gttctcgtac
     2041 agagattgaa acgactaaga ctggtcgtga gcgtatcgtt gtaacagaat ttccttacat
     2101 ggtcaataaa accaaggtgc atgagcatat tgttcgcttg gttcaggaaa aacgcattga
     2161 gggtatcaca gcagtacgtg atgagtcaaa ccgtgaaggt gttcgatttg ttattgaagt
     2221 caagcgcgac gcctcagcca atgttattct caataacctc ttcaaaatga cccaaatgca
     2281 aaccaatttt ggattcaata tgctcgctat ccaaaatggt ataccgaaaa ttttgtctct
     2341 tcgtcagatt ttggatgctt atattgagca ccaaaaagaa gtggttgttc gtcgtacacg
     2401 ttttgataag gaaaaagcgg aagcgcgcgc tcatatctta gaaggtctct tgattgcgct
     2461 agaccatatc gacgaagtga ttcgtatcat ccgtgctagt gaaacggatg cggaagctca
     2521 agctgagttg atgagcaagt ttaagctttc tgaacgtcaa agtcaagcta tccttgatat
     2581 gcgtcttcgt cgtttgacag gtttggaacg cgataagatt caatctgagt atgatgacct
     2641 cttggctctg attgcggatt tagcagatat tcttgctaag cctgaacgtg tttctcaaat
     2701 tatcaaagac gaattggatg aagttaaacg taaattttct gataaacgcc gtacagagtt
     2761 gatggttgga cagatcttga gtctcgagga tgaggacttg attgaagaat cggatgtctt
     2821 gattaccctt tctaacagag gctacattaa gcgtttggat caggacgagt tcactgctca
     2881 aaaacgtggg ggtcgtggtg tccaaggaac gggagtgaaa gatgatgact ttgttcgtga
     2941 gttagtgtca actagcaccc atgatcatct gctcttcttc acaaacaaag gacgtgtcta
     3001 tcgtctgaaa ggttatgaaa ttcctgagta tggtcggact gccaaagggc taccagtagt
     3061 caatctcttg aaattggatg aagatgaaag tattcagacg gttatcaatg ctgagtctga
     3121 tcgcagtgat gatgcttatc tcttctttac aacccgtcac ggtattgtga agagaactag
     3181 tgttaaggag tttgccaata ttcgtcaaaa tggtctcaaa gcgctgaatt taaaggatga
     3241 agatgagtta atcaatgtct tgttgacaga aggagatatg gatattatca ttggtaccaa
     3301 gtttggttat gcagttcgct ttaatcaatc agccgttcgt ggtatgagcc gtatcgccac
     3361 tggtgtgaaa ggtgttaacc ttcgtgaagg agacacagtt gttggtgcca gcttgattac
     3421 tgatcaagat gaggttctta ttatcacaga aaaaggatat ggtaagcgta cagtcgctac
     3481 tgaataccca acaaaaggtc gtggtggtaa gggaatgcag acagctaaaa ttaccgaaaa
     3541 aaatggcttg ctggccggtc ttatgactgt tcaaggggat gaggatttga tgattatcac
     3601 tgatacaggt gtcatgattc gaaccaatct tgccaatatt tcacaaacag gacgtgcaac
     3661 tatgggagtt aaagtaatgc gcctggatca agatgctcag atagtgactt tcacaacggt
     3721 tgcggtggca gaaaaagaag aagttgggac agaaaacgaa acagaaggtg aagcataatg
     3781 tctcaaaaaa ataataaaaa gaaaaacaag cgaaaaaatc tgctgacaaa tatcctagca
     3841 ggatttctga tattactgtc actggctttg atttttaata ctcaaattcg aaatattttc
     3901 atagtctgga ataccaataa gtatcaagtt agccaggtat caaaagaaaa attagaagaa
     3961 aatcaggata cagaaggcaa ttttgacttt gattctgtca aagctatctc ttcggaagct
     4021 gttctaactt ctcaatggga tgctcaaaaa ttaccagtta ttgggggaat tgcaattcct
     4081 gaattggaaa tgaatttgcc gatttttaaa ggacttgata atgttaatct cttctacgga
     4141 gctggtacaa tgaaacgcga gcaagtaatg ggagaaggaa attatagtct agctagtcac
     4201 catatctttg gtgttgataa tgctaataaa atgttatttt ctcctttaga taatgctaaa
     4261 aatggcatga agatttatct aaccgataaa aataaagttt atacttatga aatacgtgaa
     4321 gtcaaacgtg tgacaccgga tcgtgttgat gaagttgatg atagagatgg ggtcaatgaa
     4381 atcacattag taacctgtga agaccttgct gctacagaac gtattattgt caaaggtgat
     4441 ttgaaagaaa caaaagatta ttcacaaaca tctgatgaaa t
//
LOCUS       DAVKBK010000089         4439 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVKBK010000089 DAVKBK010000000
VERSION     DAVKBK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.089"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            144..1346
                     /locus_tag="VWX69_001911"
     CDS             144..1346
                     /locus_tag="VWX69_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU9193196.1"
                     /translation="MKILFVNMFYNEAGGAQKSTKFLAEQLVKEGHEVFAYSDDAIDS
                     DIDEVINRVKIFRRRTPLFSLHYIFSAKKNPAKHFFYKIFETYNVFAKRKFINIIEEV
                     QPDIVHFNTISGMSLSIVKEAKKRNIRTVWTLRDYWLEYPWGEKDISLIKLLNRIYRP
                     FVKKSLRHLDIVTAPSAFTLNNFINKGFINPSSQKCMVIENAVIFSKGKLENIIKQKQ
                     ETKRNPEKTNFLFVGSILEIKGVFNLVKAFKKLTSPEISLKIVGKGKDLEKLQKEIES
                     DPRIQYLGFQDTETLYKTYQNSDVLVVPSAWDEPFGRVVIEGNANGLPVITSDRGGLP
                     EIVQTVGGGEIFTDESGNTLYSLLKKFVEMENYNVYYQCILENIDIYSIEKQSEKFTN
                     LYLDKEIE"
     gene            1380..2612
                     /locus_tag="VWX69_001912"
     CDS             1380..2612
                     /locus_tag="VWX69_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU9193197.1"
                     /translation="MKIAVAGTGYVGLSIAVLLAQHHEIKAVDIVAEKVELINQKKSP
                     IQDDYIEKYLVEKDLNLEATMDAKYAYEDAEFVVVAAPTNYDSKKNFFDTSAVEAVIQ
                     QVKKINPKAVIIIKSTIPVGFTESVQKKYQYKNILFSPEFLRESKALYDNLYPSRIIV
                     GTDLEDTYLKDKANIFASLLKEGAIKEDIDTLFMGVTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEVKGLDAKAIIDGIGLDPRIGNHYNNPSFGYGGYCLPKDSKQLLANYFDVPQ
                     NMMTATVESNRTRKDFIAQRILEKAGVSETDSLDAFKNIQDIVIGIYRLTMKSNSDNF
                     RHSSIQGVMKRLKAKGVTVIIYEPTLKDGETFFGNKVVNNLDKFKEASNVIVANRFEP
                     SLEDVSNKVYSRDIFKRD"
     gene            2831..3585
                     /locus_tag="VWX69_001913"
                     /pseudo
     CDS             2831..3585
                     /locus_tag="VWX69_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            3980..4366
                     /locus_tag="VWX69_001914"
     CDS             3980..4366
                     /locus_tag="VWX69_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase"
                     /protein_id="HEU9193198.1"
                     /translation="MFAWFLFYEVGSKKDYVSYINPGLWGIAFIVCVLVAFAIFPKME
                     KNFPKTFLYFTKYGKDSLGIYILHAPICSMIRILMLKVGINSVFLHVVVGIVLGWYLS
                     ILATYILKKIPFLNIVLLPQKYIKLK"
BASE COUNT         1516 a          625 c          826 g         1472 t
ORIGIN      
        1 ttatctcgga ttttgtaaac gaccttattt tacatttatc agttcagttt gttattttat
       61 ttttaatatg gggaattggg atgtatatta gcggagagta tcgacgagtc ttcgcggtta
      121 taagaaaata aaggagcaat tttgtgaaaa ttttatttgt gaatatgttt tataatgaag
      181 caggaggtgc acaaaagagc accaaatttc tagctgaaca acttgtaaaa gaaggacatg
      241 aggtatttgc atactctgat gatgccattg attcagatat tgatgaagtt attaataggg
      301 ttaagatttt tagaagaaga accccgcttt ttagtcttca ctatattttc agtgctaaga
      361 agaatccagc taaacatttt ttctataaaa tatttgaaac ctataatgta tttgcgaaaa
      421 gaaaatttat caatatcatt gaggaagtac aaccagatat tgttcacttt aatacaattt
      481 caggaatgtc tttatcaata gttaaagaag ctaaaaagag aaatatcagg accgtttgga
      541 ccttgcgaga ctattggcta gaatatccat ggggtgagaa agatatttct cttatcaaac
      601 ttctaaatag aatatataga ccttttgtta agaaaagttt aagacactta gacatagtaa
      661 cagcaccatc agcatttact ttgaataatt ttatcaataa aggatttatt aacccatctt
      721 ctcaaaaatg tatggtcatt gaaaatgctg ttatattttc aaagggtaag ttggaaaata
      781 ttatcaaaca aaagcaagaa acaaaaagaa atccagaaaa aacgaatttt ctttttgtag
      841 gttctatact tgaaataaag ggcgttttta acttagtaaa ggcctttaaa aaactaacta
      901 gtccggaaat ttctttgaaa attgtaggaa aaggaaaaga tttagaaaaa cttcaaaaag
      961 aaattgagag tgatcctaga atacaatatt taggctttca agatacagaa accctctata
     1021 aaacttatca aaattcggat gtattggtcg tcccatctgc ttgggatgaa ccgtttggta
     1081 gagttgtaat tgaaggaaat gcaaatggcc ttcctgtcat cacttcagat agaggtggat
     1141 tacctgaaat tgtgcaaaca gtaggaggag gagaaatttt tacagatgaa tcgggaaata
     1201 cattatatag tcttttaaag aaatttgtag aaatggaaaa ctacaatgtc tattaccaat
     1261 gcattcttga gaatattgat atttattcta tcgaaaaaca aagtgaaaag ttcactaatc
     1321 tgtatttaga taaagaaatc gaataataag ttgtttttgt agcagtaacg gaggtaatta
     1381 tgaaaatagc ggtagcagga acaggttatg taggattatc aattgctgtg ttgttggcac
     1441 aacatcacga aataaaagca gttgatattg ttgctgaaaa agttgaatta atcaatcaaa
     1501 aaaagtctcc aattcaggat gattatattg aaaaatattt agtggaaaaa gatttaaatt
     1561 tggaagcaac tatggatgct aagtatgctt atgaagatgc agaatttgtt gttgttgcag
     1621 caccaacaaa ttatgattcg aaaaagaact tttttgatac atcagcagta gaggcggtca
     1681 ttcaacaagt aaaaaaaatt aatcccaaag cggtaataat tattaaatct acaatccctg
     1741 ttggattcac agagtccgtt caaaagaaat atcagtataa aaatatctta tttagtccag
     1801 aatttttacg cgaatctaaa gcattatacg ataacctgta tccaagtcgc atcattgttg
     1861 gaactgactt agaagatact tatttaaaag acaaagctaa tatatttgct tccctactaa
     1921 aagagggggc tattaaagaa gacatagata cacttttcat gggagtaacg gaagctgagg
     1981 cagttaaatt atttgccaat acctaccttg cgttgcgtgt ttcttacttt aatgaattgg
     2041 atacttatgc agaggtgaaa ggtttggatg caaaagccat tattgatggt attggcctag
     2101 atccacgtat aggaaatcat tataacaatc catcctttgg ctacggtggg tattgtttac
     2161 ctaaagatag taagcagtta ttagcaaatt actttgatgt accacaaaat atgatgacag
     2221 caactgttga aagcaatcga acgcgtaagg attttatcgc tcaacggatt ttagaaaaag
     2281 ctggagtatc tgagactgat agtttagatg cgtttaagaa catacaagat attgttatag
     2341 gtatttatcg tttaacaatg aaaagtaatt cggataactt ccgtcactcc tctattcaag
     2401 gcgttatgaa acgattgaaa gctaagggag ttacggttat catctatgag ccaactttga
     2461 aggacgggga aacattcttt ggtaataaag tggtaaataa tctagataaa tttaaagaag
     2521 ctagtaatgt tattgtagcc aatcgttttg aaccttcact agaggatgtg tctaataaag
     2581 tttatagtcg agatatattt aagcgtgact aataaatacg tccacgtgac gtaatatcta
     2641 ttaaatgaat aaaatattaa taaacatggc atcgatatct tttttggact tgaattgtca
     2701 aattaagtgc acattttttt catagaaaac ttcataaggt gttttccggt taagacattt
     2761 tcgtggtcta ttatctaagt tggtttatat aatagacttc ctgcgaaaca aaatatggta
     2821 taatagttct atgaattatg aagcaagtaa acaactaacc gatgtacgat ttaagcgtct
     2881 tgttggtgtt caacgcacga cttttgaaga gatgttagct gtattaaaaa cagcttatca
     2941 acttaaacac gcaaaaggtg gacgaaaacc taaattaagc ctagaagact ttcttatggc
     3001 gactcttcaa taagtgcgag aataccgcac ttatgaacaa attgcggctg attttggtat
     3061 tcacgaaagc aacttaatcc gtcggagcta atgggttgaa gtaactcttg ttcaaaggtg
     3121 gtgttacgat ttcaagaact cctctcagtt ctgaggacac ggtaatgatt gatgcgacgg
     3181 aagtaaaaat caatcgccct aaaaaaagaa ttagcgaatt attctggtaa aaagaaattt
     3241 cacgctatga agactcaagc gattgtcaca agtcaaggga gaattgtttc tttggatatc
     3301 actgtgaact attgtcatga tatgaagttg ttcaaaatga gtcgcagaaa tatcggacaa
     3361 gctggtaaaa tcttggctga cagtggttat caagggctca tgaagatata tcctcaagca
     3421 caaattccac gtaaatccag caaactcaag ccgctaatag ctgaagataa agcctataac
     3481 catgcactgt ctaaggatag aagcaaggtt gagaacatcc ttgccaaagt aaaaacgttt
     3541 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct tcggatattt taggcatact
     3601 atatattttt tattcaatta ttcacttttg tattcaaaag gttgcgggtg cctctgtccg
     3661 agtacccact atgatattta acctattgaa tatctataaa tttcctctgg gagtttcatg
     3721 gtatctatat acgttatggt cgatattgat agtttatggt ttactatctg ttgttttcaa
     3781 aaatcgtaag tcccttttgt tagttagtgt ttttgcctat attttcacac tatttattca
     3841 aactgatatt tttattgtgc aacggacgtt ggtttggggg atttgtttct ttcttggcag
     3901 tgtattgagt gaaattcact ttgataaaat taatttgaaa aaatttcttt ttttctttgt
     3961 gttatttgat tttatttata tgttcgcttg gttcttgttt tatgaagtag ggtctaagaa
     4021 ggattatgta agctatatta acccaggttt gtgggggatt gcttttattg tctgtgtatt
     4081 agttgctttt gcgatttttc ctaaaatgga gaaaaatttt cctaaaactt tcctatattt
     4141 cactaaatac gggaaagata gtttagggat ctatattctt catgcaccaa tttgtagcat
     4201 gattcggatt ctaatgttga aagtgggaat aaactcagtt tttcttcacg ttgttgttgg
     4261 gattgtgcta ggctggtatt tatccatact agcaacttat atattgaaaa aaattccatt
     4321 tttgaatatt gttttattac cacaaaagta tattaaatta aaataaatta ttttagattt
     4381 ataatgtggc tctttgtcaa ctaacatctg gagaggacaa tcactgtctt ctctttttt
//
LOCUS       DAVKBK010000090         4328 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVKBK010000090 DAVKBK010000000
VERSION     DAVKBK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.090"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(204..620)
                     /locus_tag="VWX69_001915"
     CDS             complement(204..620)
                     /locus_tag="VWX69_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9193199.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(632..1327)
                     /locus_tag="VWX69_001916"
     CDS             complement(632..1327)
                     /locus_tag="VWX69_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9193200.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            complement(1521..4022)
                     /locus_tag="VWX69_001917"
     CDS             complement(1521..4022)
                     /locus_tag="VWX69_001917"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU9193201.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
BASE COUNT         1204 a          998 c          827 g         1299 t
ORIGIN      
        1 ttttctaaaa ttttactatt ttgcaaaaaa tttctatcac cagcacctca ccacgcaaaa
       61 aagccacctg attgggtggc ttcattagga gattgtgatg aaaaaagttt aggattttat
      121 taaataaagt taggaggtct ttatttaatg actatataat actagaccat ccttaaattt
      181 tgcttaagaa aaaacaagtt ttgttatttt ttacgattca tccaagtcat ccctatacaa
      241 ttataggtgg ataagatttc aaagcccata gaacgataga agcccaaggt tctttctgtc
      301 tcttctgtca ccagctggac ttgataggca tctttgtaat cctctaaagc ctctttcatc
      361 aaggcactac caattccttg acgctgatag attggtaaaa cgattaaatc ctgaaccaat
      421 actgatgaga atccatctcc aaccaaacga atcaagccca ccacagcatc accatcaagt
      481 gccagataaa ttactaatga atgagataag gcctgctcca gcatctctgg ttgatgggta
      541 taatttgtcc aaccgacagc ctgatagaga tgtaaaacat cctctagctt gacaatttct
      601 tgctttttaa tagtaatcat ctcaacacct cttaaagttc tctcaagctc ttgtactgct
      661 gtccattttt atcaaaattt tcaggacgca accatgtttc caaacgatct ttgacttgag
      721 gccagtcctt atcaatcata gacaaccaat ccgtatctct cgtacgtccc ttataaacca
      781 ctgcctgacg gaaggttcct tcataaataa agctcaaacg ctccgcagct cgtctggatg
      841 gcagatttaa ggcatcgcat ttccactcgt agcgacgata gtttagctcc tcaaaaacat
      901 agcgagctag gagatactga gcttcagttc ctatccgtgt accccttagc tctggagaaa
      961 aagtgactgc tccgacttct attactcggt tattctggtc aatgcgcatg agagaaaaag
     1021 atcccaaagc cttaccagtc gccttgtcta tgattgcata gtaaaaacgg tccttacgag
     1081 ccaacatctg atgtaaaagg ctaaccagct cccccatatc tgctactggc tcctgaaaaa
     1141 ggtaggtcca catctcccga ggagtatccg ggccataaac agctagcaaa tcctccgcat
     1201 gcttttccac tgaaagagcc tctatcctag cataacgccc ttctaagaaa tcaatagaag
     1261 gcagttcacc tggtgtataa ccttccattg actccccaat catttgacca tattcattta
     1321 ctggcatagc tttctccttt tttcactttt caaactttat agttgcccat agtataccat
     1381 actttcataa gaagattcaa aaaatcctcc agattctact ctgaaggatt cctaccttat
     1441 ttcacaacga tattaacgag tttagttggc tcaaacagtt tgggaaactg tttgaggttg
     1501 gaaatcagca aataaattgg ttattttaca acaatattaa ccaatttatt tggtacacta
     1561 atcactttca cgatttcctt accgtcaatt tctgctttga ctttttcatc cgctagagca
     1621 atttcttgca attcttcacg tgataggtct ttagcgacca tgagtttggc acggacttta
     1681 cctttgattt ggacaacgat ttcgatttcg tcttcaacca gtttactttc gtcccaagtt
     1741 ggccaagcta cataagagat tgactcacct gtttctgcga ctgtttgcca gagttcttct
     1801 gccaagtgag gtgcaaatgg tgcaatcaat tgaataaagc ctttggcata gtcaacataa
     1861 agcttatctt ccttgttagc agcattgaca aagaccataa gttgggcaat agctgtgttg
     1921 aatttgagag actcaatttg ctcagtaaca gctttgactg tttcgttgta agccttgtca
     1981 agagcaccat tgttttccgc aaggatttct ttacttgtaa tcaaacggta aactcggtca
     2041 aggaacttac ggcttccttc caaaccttct tctgaccaag caatcgaagc atcgagtggt
     2101 cccataaaca tttcataaac acgaagggta tcggcaccgt attgttccac cacatcatct
     2161 gggttaacaa cgttcttgag cgatttagac atcttggctg gcgcttgctc caactcttcc
     2221 cctgtttcta tatgaaagaa ggaaccatca cgtttttcaa ccttgtcggt tgccacaaga
     2281 gcaccacggt ggtcacggta gcttgttccc aaaatcatcc cttggttaaa gagtttttgg
     2341 aatggttcct tagtcggaac aacaccgagg tcatagagga atttatgcca gaaacgagca
     2401 taaagcaagt gaagtacagc atgttccgca ccacccacgt agatatctac tggcaaccat
     2461 tgtttgagga ggtcctcatc agccaatttc tcagtattgt gcgggtcaat atagcggagg
     2521 tagtaccagc ttgaaccagc ccattgtggc atggtgttag tttcacgacg acctttgaca
     2581 ccatcttcac gagtcacttc aagccaatct gtcaagttag ctagtggact ttcaccagta
     2641 cctgaaggac ggatatcctt ggttacaggc aagacaagcg gcaattcagt ttcaggaaca
     2701 gctgttgaag ttccatcttc ccaatgaatg attggaattg gctcacccca gtaacgttga
     2761 cggctaaaga gccagtcgcg gaggcggtag gtaaccttct cctgaccaca gcctttttct
     2821 tccaagcaag ccacaatctt ggcaatagcg tcttctttgt tcaatccatc taggaagtct
     2881 gaattgacat gcaggccatc ctctgtgtag gcagcttctt cgacatttcc accttcaagt
     2941 acttcgacga ttggaaggtc aaattgtttg gcaaattccc agtcacgttg gtcgtgggca
     3001 ggcacagcca taaccgcacc tgttccataa ctagcaagaa catagtccgc aatccagatt
     3061 ggcatttcct taccattgac agggttgatg gcataggcac ctgtccaaac accagttttt
     3121 tccttagcaa ggtctgtacg aaccaagtca gacttaaggc tggcttggtg tttatagtct
     3181 gctacagctt ctgcttgctc tgaacttgtg atagcgtcta ctaattcatg ttcaggagcc
     3241 aagacagtga aagtcgcacc gaaaagtgtg tccggacgag tagtaaagac tgtaaattcc
     3301 ttgtctgttc cttttacttt gaaagttaca ttggcaccag ttgatttacc aatccagttg
     3361 cgttgcatat ccttgataga ctctgaccaa tctagttcat ctaagtcatt gagcaagcgc
     3421 tctgcgtaag ccgtgatttt gagcatccat tggcgcattg gtttgcggac aactggatag
     3481 cctccacgct cagaagttcc gtcaggaagc acttcttcat tggcaatggc agttcccaat
     3541 tcctcaaccc agtttactgg cacttcagct tcataggcca agcctttttc gtaaagcttg
     3601 gtgaaaatcc attgagtcca cttgtagtag tttggatctg ttgtattgac ttcacgatcc
     3661 cagtcataag aaaatccaag cgcattgatt tgacgtttga agttggcaat gttttccgct
     3721 gtaaattctg ctgggtcatt accagtatcc atagcgtatt gctctgcagg caaaccaaaa
     3781 gcatcccaac ccattgggtg aaggacattg tagccttgcg cacgtttgta acgactgagg
     3841 atatcggttg cagtataacc ttctgggtgt cctacgtgca gaccagctcc agacggataa
     3901 gggaacatat caagcgcata aaacttaggt tttgatgcat ctgttcctgt cttaaatgta
     3961 tgatgttctg cccagtagcc ctgccactta ggctcaattt ctttatgatt gtaaaaactc
     4021 atggtctctc tccaattttg tgatgttact attataccat ttttgaggga atttgaaatg
     4081 tgtttaaagg aaaaactgta tactgtatct cattaatttt gatgactatg aattgctcta
     4141 tctcccactt tttatcccat tgttatgcag taaatcaagg agtaagtcaa gacgcttatc
     4201 tcgtatagca caaaatactt attttagacc gaagataaaa ctggaatgct aattaatgta
     4261 ttcacaataa atagccgaca acctatgtcg ctttttgatt tatgaagaac gtatagtaga
     4321 ctgaatct
//
LOCUS       DAVKBK010000091         4269 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVKBK010000091 DAVKBK010000000
VERSION     DAVKBK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.091"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            96..862
                     /locus_tag="VWX69_001918"
                     /pseudo
     CDS             96..862
                     /locus_tag="VWX69_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850213.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1694..2053
                     /locus_tag="VWX69_001919"
     CDS             1694..2053
                     /locus_tag="VWX69_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193202.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            2063..2392
                     /locus_tag="VWX69_001920"
     CDS             2063..2392
                     /locus_tag="VWX69_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU9193203.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQV"
     gene            2415..4269
                     /locus_tag="VWX69_001921"
                     /pseudo
     CDS             2415..4269
                     /locus_tag="VWX69_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
BASE COUNT         1591 a          613 c          823 g         1242 t
ORIGIN      
        1 aggcaatcat aaaaaatgga atagaaatag ttgtagtaac tgatcataat actaccaaag
       61 gtattaaaaa gttacaaatg gcagtctcaa tcataatgaa aaattatccg atttatgata
      121 tacatcctca tattttacat ggagtagaaa ttagtgcagc agataaattg catattgtat
      181 gtatatatga ttatgaacaa gaatcatggg ttaatcaatg gttaagtgaa aatattataa
      241 gtgagaaaga tggaagttat caacattcac tgactataat gaaggatttc aataatcaaa
      301 aaatagttaa ctatattgct catttcaata gttatgacat tttgaaaaaa ggttctcact
      361 tatcaggtgc atataaacga aaaatttttt ctaaagaaaa tacacgattt tggagtttaa
      421 tattaactcg aaagaatttt cgcaacaact tgatattctc tataaagaag ttggtgtatt
      481 aagtttggga caaaaagttg tagccatgct tgatttttta ttagcatata gtgattattc
      541 taaagacttc agaccattga ttattgatca gcctgaagac aatctagaca atcgttatat
      601 ttacaggcat ttagttcagc agtttagaga tgtgaaagct caacgtcaaa ttattttagc
      661 aacacataat gctacaattg taacaaattc tatgacagat caagttgtta ttatggagtc
      721 agatggagtt aacggatgga ttgaatcaca gggatatgtt agtgaaaaat atataaaaaa
      781 tcatatcatc aatcaattag agggaggaaa agattccttc aagcataaaa tgtctatata
      841 tgagacggct ttatcagagt agagtcagaa aaagtaggtt agaaatttag cctacttttt
      901 tctttgtccg acaggcatag tgtacatctg aggtccaagt cctctgtgga tatttgctgc
      961 agatgaaacc aatagcgact cctaagcctg aatatcgtga ggtagggggg ataggaagga
     1021 attagcgaaa tcaaggttct acaaacagaa tcgtgacttg aagccatata tagcggatga
     1081 ggaactctaa aatccaaata ggtgtcgtaa cctatatacg taaattacga gagtaaacta
     1141 ggaaagatgt acggcttatt ccgtgagcgt ttaggacgta gtacaacgaa tcatgggagt
     1201 cagctgaaca catagtattg aagaaatttc tgtaatggaa atggagcgaa gaagtgaaca
     1261 attaaatgaa tacctctcta attaaatttg tcaattctaa ttcctggtat gaaaagacag
     1321 tgacctgaaa atgtaaacga tgggagctga tcataaatat aggacggtac atgcagtggt
     1381 gttagagatt agtccttact tgatttgtga taacttcccc aaatttcttc tgctatactt
     1441 ttctcaactt ttaaaaatcc aactaagaat tttacctggg ggtttggggg cggagccact
     1501 aagttatctt atcgttagct gtcaaaactg gtaggttttg ataggctggc gatatgattt
     1561 ttgggatatt gtggacacaa tatctgagct cgcaaagacc gaacaaggag agactgaggt
     1621 ctttaggaat cgtactgaca atgtgaggca gccttacatt gtcagacaag tataatgttg
     1681 aaagaatggt aagatgggac aagaaattaa gttaatccgt aagcaattta gaatcacgag
     1741 acaagaagaa aaacagataa aagaaatgat gagggaacaa aaagtggata gtttctcaga
     1801 atttcttcgt caaaatttat tgaaaaagaa ttatcaggat agaatttttg aaagttggtt
     1861 ctccctttgg cagtctcaaa agtttgaaca gattagtcga gatgtgtatg aagttctggt
     1921 tgtcgcaaga gaaaatcatc aagtgactca agagcacgtc tcaatcttat tgacttgcgt
     1981 tcaagaattg attgcagaag tgaatcaagt acagccactc agtcgtgagt ttcgtgaaaa
     2041 atatatgggt taggaggatg taatggttta tcgctatcgt accaatctca aaaaagtatt
     2101 tctaactgat ccagaattac accaattgaa tgaacggatt gctaagagca attgtcaaaa
     2161 tttttcagtc tatgccagaa aagttttgct taatcccaat atgtcatttg tcacgattaa
     2221 cactgatact tatgaccagt tagtttttga attgagacgt attggaaata acatcaatca
     2281 aattgcgcgt gcgattaatc aaagccatct gatttctcag gaccaattac aagaattgag
     2341 taaaggagtc ggagagttaa ttaaggaagt ggacaaagaa tttcaagtgt aggtgaaaag
     2401 actgaaggag tttcatggta gttactaaac actttgcgac gcacggaaaa aaatatcgta
     2461 ggcgtttgat taaatatatc ctcaatccag ataaaacaga taatctaaaa ttagtatctg
     2521 attttggcat gagtaattac ttagattttc ctagccatac agaaatggta gaaatgtaca
     2581 atgttaactt tactaataac gacaagttgt acgagtccag aaatgaccga caagaaaaac
     2641 accaacaaac tattcatgcc catcatctca tccaatcatt ttctcctgaa gataatctga
     2701 cacctgaaga aattaaccgc attggttatg agaccatgat ggaattgaca ggaggtcgtt
     2761 ttaagtttat cgtagcaact cacacagaca aagatcatgt tcataatcac atcctaatca
     2821 acgctattga ccgcaattca gataaaaagt tgatatggaa ctatgccttg gaacgaaacc
     2881 tccgtatgat ttcagaccgt atttctaaaa tggctggtgc aaaaattatt gagaaacgtt
     2941 attcttatcg aggttataaa aaatataggg aatctagtca taaatttgaa ttgaaacaac
     3001 gtctttattt tttgatgcag caatctaaat agtttgatga ttttttagag aaagcaaagc
     3061 agttgcatgt tcagattgat tttagtcaaa agcatagtcg attcatgatg acggatcgag
     3121 caatgacaaa acctattcga ggacgccaac tcagcaaacg agatctatat gatgaagaat
     3181 tttttagaac gcattttgct aagcaagaga ttgaaagtcg tttagaattt ttgttgaacc
     3241 gtgtcaattc tttagaagag ttaataacaa aagcaaaaga attgaatcta accattgact
     3301 taaaacaaaa aaatgtaact tttatcctga aagaaaataa tcaaaagata agtttgggtc
     3361 atcaaaaaat aagtgataag aaattatatg atgtcaaatt ttttcaagat tattttaaaa
     3421 ataaggaagt cattgcttca gaaggattag agaatttaca ggaacagtac catgctttcc
     3481 aagaagaacg agataaggat aaagtatcca ctgaagagat tgaggaagcc tttaagacat
     3541 ttaagaagcc tttaagacat ttaaggaaaa atgagatacc gttcgtgaat ttgaagtgga
     3601 acttgcagag aaccaaatag agaagctagt tgataagggc gtctatatca aggtgtcttt
     3661 cggtgtcaaa tagagcggtc ttattttcat tcccaactat caattggata ttatggaaga
     3721 agaaaatcat aaaaaatata aagtctacat tcgagaaacg tcttcttact ttgtctataa
     3781 taaagaaaac atggataata attgtttcat caagggtagg accttaatca gacaattgag
     3841 caacgatagc caaaaactcc cctatagacg accaacttta aaaagtcttc aagagaagat
     3901 ttctgaaatt aatcttatga ttgaactatc taacacgaac aaacaatacc aagaaatcaa
     3961 agatgagctt gtattagaaa ttgcagagat tgatatgaag ctagaagaaa cccaagaaaa
     4021 aatcgccacc ttaaacaaga tggcggaagt ccttatcaat ttgaagagtg aagatgagat
     4081 cggtagaaaa ttagctaagt atgattttga ccaaatgaac atgacggaat caataatgtt
     4141 agatcgactc aatacatata ttttaaaatt acaacaggaa cttagtaatg aaattaataa
     4201 atatgaggag atagctagaa gattggattt gtttgtgaaa attattaata ccaataaatt
     4261 tacagttct
//
LOCUS       DAVKBK010000092         4136 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVKBK010000092 DAVKBK010000000
VERSION     DAVKBK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.092"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            720..1712
                     /locus_tag="VWX69_001922"
     CDS             720..1712
                     /locus_tag="VWX69_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9193204.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VWX69_001923"
     CDS             1714..2532
                     /locus_tag="VWX69_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU9193205.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VWX69_001924"
     CDS             2534..3319
                     /locus_tag="VWX69_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9193206.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VWX69_001925"
     CDS             3417..3635
                     /locus_tag="VWX69_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU9193207.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3781
                     /locus_tag="VWX69_001926"
     CDS             3620..3781
                     /locus_tag="VWX69_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU9193208.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
BASE COUNT         1153 a          703 c          896 g         1384 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta caaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tatttcatga
      541 gagaaatcct aatttcacaa tctataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttctgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aacattttgt gaagattgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg agcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca aaagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttcg tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttaatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgtt gaggttttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca agcctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaaggttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagg ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt tctcagctat ggaatccgta
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctattctcag
     3841 agtgccatac tgtaagtgta atcgccgatt tagctcagtt ggtagagcaa ggcactcgta
     3901 aagcctaggt tataggtaga taaacgactg aggagttgaa aaaatagata ggtagaagat
     3961 aaccgttaag ccttattctt agcggttatt tatattgttt aatagcgctg atatttcatc
     4021 aattatgcct gttttcgtgt ttctggtagt tgttcaagtt tattgctact atttttgatg
     4081 gtatgaatgt gcttataatg tatcccggtt aacgaaagtt ttggacttat actcat
//
LOCUS       DAVKBK010000093         4095 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVKBK010000093 DAVKBK010000000
VERSION     DAVKBK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.093"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(160..1575)
                     /locus_tag="VWX69_001927"
     CDS             complement(160..1575)
                     /locus_tag="VWX69_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9193209.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1588..3426)
                     /locus_tag="VWX69_001928"
     CDS             complement(1588..3426)
                     /locus_tag="VWX69_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9193210.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3444..>4095)
                     /locus_tag="VWX69_001929"
     CDS             complement(3444..>4095)
                     /locus_tag="VWX69_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU9193211.1"
                     /translation="INVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHISSSIER
                     YKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHFVNANL
                     ENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVENTTYCD
                     DDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTKNLD"
BASE COUNT         1375 a          817 c          536 g         1367 t
ORIGIN      
        1 agttaactat ttataatcgg ctctctgtaa caaaattaaa ttaattaatc cccctataaa
       61 ataaagaggt ttagaatttg atgtcttcca aacctcttta tttcatattt aatgagatgc
      121 tgccttaacc gtgataatat ctaatcatca ataaacaaac tatttgaata aggattctcc
      181 atttgattca atcactcctt tataccaagt aaaggacatt ttcttatatc gattgaatgt
      241 gccatttcca tcatcatttc gatcaacata aatgagaccg tacctcttag aaagctgtgc
      301 agtggacata gaaacgcagt caatacatcc ccaagacgta tagcccataa tttccacacc
      361 atcttgtaga gcttcagcta cttgcaataa atgttctttc atatactgaa ttctataatc
      421 atcttggact gttaagttat taaattcatc ttttattagt tgatctttag cacctaatcc
      481 gttttccact ataaataatg gaatttgata acggtcataa tatctattta aaattatacg
      541 tagtccaatt ggatcaattt gccatcccca ctcagaagac tctaaataag gatttactaa
      601 accaccaata atattccctt ctcctgaatt atactgtgtt ggaagagcag attgagtcac
      661 actcatgtaa tagctaaagg ataaaaaatc tacagtataa ttttttaata actctgcatc
      721 ttcagctgca aactctatgt taatgtcatt ttccttaaaa tatctttttg cataattcgg
      781 ataataacct ctaacatgca catctgaaaa tagataattt agattctcat actcatgagt
      841 cgcccataca tcttttggat ttggagtcat tggataagct ggcatagcta ataccataca
      901 ccccacctta aactctgaat taatctcacg agcaattttt gtaaccaaac tcgaggcgac
      961 taattcatga tgtatagctt gatataattc ttgtttcgaa agattctcct taggtatatc
     1021 tattcctcca ctagtaaacg gtaattccaa aacagagttt acttcgttaa atgtaagcca
     1081 atatttaact ttatctttat acctttctaa aactgttcga gcaaattttt cataaaaatg
     1141 aatcattctc ctatcaatcc atccatgata ttttcttgct aaatataatg gagtctcata
     1201 gtgtgaaaga gttacaagtg gttctatccc gtgagcatgt agttcatcaa acaattcatc
     1261 ataatatttc aacccagctt cgttaggttc ttcctcatct ccttttggaa aaattctact
     1321 ccatgcaata gaagtacgaa aaacattaaa gcccatttca gaaaacaagg atatatcttc
     1381 cttatattta tgataaaaat caatacctat caattttaag ttatcttctg taggattttc
     1441 tgttgcttct cctaatccac ctttgggtaa cacatcctga actgataagc ccttaccatc
     1501 ttcattatat gctccctcta cttgattagc tgcaacagct ccaccccaaa gaaaatcatc
     1561 tggaaaaatg gtcataactt tcctccatta taatattacc agtaattcct tagaatgctc
     1621 gattgtctga ttattaggta atactaatac atctagaaaa tcattggtat tcgttacaat
     1681 tactggtgta actgtttcgt agcctttagt cttgattaaa ttcaagtcca tttcaaaaat
     1741 caactgattt ttgaaaactc tgtctccttc ttctacatga ctaataaaac cttgaccttt
     1801 tagctcaaca gtatctaatc caatatgaat tagtaactca acaccctcat cactcttcaa
     1861 tccaattgcg tgcttagtcg gaaaaatatt tgtaattttc ccatcaaatg gtgcataaac
     1921 cttaccttca cttggaataa tcgctactcc gtctccaatt agtttatctg aaaatgtttt
     1981 atcctggaca tcgcttaacg gaatgatttc tcctgatata ggagaaaata tcattttttt
     2041 atttgaaact ccagctttaa cttctaaatt gctagaactc tcttcttcat cgattccaaa
     2101 tatataagct aatacaaagg taataacaac cgaaataacc gccacaatta aagcatttac
     2161 aatatttgat ggcacatcag aataaataaa ttgaggcaac gctatcaaag atgggacagc
     2221 aaatagatac gctttaacac tagtaagacc tgcaaataat cccgctaatc caccaccaat
     2281 catagctgca taaagcggtt ttttatattt taaagtcaca ccatataatg caggttcggt
     2341 aatccctgca agtaaggctg agaaacctgc tgcaaaagca atttgttttg tattattatt
     2401 tttactcttt aatgcaacag ccatcgaagc agccccttga gctaagtttg accctaacat
     2461 tgctggaaga attaatacgt ctggagtagc aatagatgcc gccaaaaaaa taggtgcaaa
     2521 agcccaatgc attccagtca taacaataaa tggcataata gcaccaagaa tagctaatgt
     2581 aagccatcca gctacaccat acatttgccc aactagattt gataatcctt caccaacaat
     2641 tactccaata ggcccgacta caactaaggc aatacagctt gatactaata atactagcgt
     2701 aggttgcaaa aaactcttag taacagctgg tgttaattta gcaatcattt tttcaatata
     2761 tttcatcaac caaaccataa taagaattgg aacgactgac gaaccataac tagctggtgt
     2821 cacaggtaca ccaaataaac taagaggatt ccctgattgc accatttgaa caaaatttgg
     2881 atggagaagt acacctgcta cagacatagc taatgtagat gttactttta atttttgtga
     2941 tgcagaataa gctaataaca gcggtaagaa ataatatgga gcatccccaa aaaatgtcaa
     3001 aaaagcaata gtctgagaat ctgattgcaa tataccaagc attggtaaaa tgattaccaa
     3061 gactttcaac atacctcccc ctaacattgc tggaatgatt ggagtcatgg aaccagcgat
     3121 atactcaatg attctttcta aaatattccc tttgtgccct tgaacaactg aatcggattc
     3181 aaaattgcca agtttaacga attctttata ataattagct acatcattac caagtataat
     3241 ttgatattgt ccattctttt tcataatacc tattacacct ggtatcttct tcacatcatc
     3301 atcattgact aaattttcat cttttaattc taatcttaaa cgtgttacac aatgggtaac
     3361 tctattgaca tttttttcac ctccaattac atcgaggatt ttttgtacct tatctttata
     3421 actcatggta ttctcctatt ctattaatct aaattttttg ttaagcgacg aatatgagcc
     3481 atcaaataaa ctaattcact agaagtcagc aaataattgt actcagtttg tataaacatt
     3541 gccacctgtt caccacattc atattctcta ggatatttat ttttcattaa tgctaacaag
     3601 tcttcatcat catcgtcaca ataagttgta ttttcaacca agcgatgggc aaataatttt
     3661 atatgagtta tgaatctata ataatcaata gaatcttggt taaactcagt acaatagaaa
     3721 tcttgaatga ttttctcaat tcccataatt atttcagtga ttttatacga ctcttgaaaa
     3781 ttattttcta aattagcatt aacaaaatgt agcgctatga atgcagcttc gtcaattgga
     3841 agttcaatac ctaactcttt ttttattatt tgtaaagccc ttttcccaag ctcaaattct
     3901 tctttataat atttcgagat ttcccagcgt aggggattcg aaataataat cccttcttta
     3961 taacgttcta tgctcgaaga aatatgatcc gttaaattaa tatagataat ttcatcaaaa
     4021 ttattcccca atgttatttt acctagatta attatttttt cggtgatgta caccaactcc
     4081 aaaggaacgt taata
//
LOCUS       DAVKBK010000094         4004 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVKBK010000094 DAVKBK010000000
VERSION     DAVKBK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.094"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..109
                     /locus_tag="VWX69_001930"
     CDS             <1..109
                     /locus_tag="VWX69_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU9193212.1"
                     /translation="KDQISSTVLPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            75..389
                     /locus_tag="VWX69_001931"
     CDS             75..389
                     /locus_tag="VWX69_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193213.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1073..1234
                     /locus_tag="VWX69_001932"
     CDS             1073..1234
                     /locus_tag="VWX69_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193214.1"
                     /translation="MNNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1326..2174
                     /locus_tag="VWX69_001933"
     CDS             1326..2174
                     /locus_tag="VWX69_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9193215.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVW"
     gene            2220..3005
                     /locus_tag="VWX69_001934"
     CDS             2220..3005
                     /locus_tag="VWX69_001934"
                     /inference="COORDINATES: protein motif:HMM:NF024800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
                     /protein_id="HEU9193216.1"
                     /translation="MNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDGTKYKDFY
                     YYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTS
                     EIEREIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKLDEL
                     ESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISALISEIQVYE
                     EKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            3273..3839
                     /locus_tag="VWX69_001935"
     CDS             3273..3839
                     /locus_tag="VWX69_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193217.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
BASE COUNT         1556 a          502 c          836 g         1110 t
ORIGIN      
        1 taaagatcaa atatctagca cagtattgcc agatatcaaa attaaattac cgatagacag
       61 tagaggtact ccagattgga attacatgga aagatataga gatagataaa gagagagagg
      121 gagagataga taaaaagtcc acccccattt tttatggaga attcaaaaat gtaaggttaa
      181 gcaaagaaga atataaaaat ctaaaagaaa aattaaactc acacacagat ataatgataa
      241 ataaactatc cagatacatg gaaagcagtg gtaagaccta tcaaaaccac tatgtgacaa
      301 tcttaaaatg gtatgaagaa gataaagaca aactaagaca gaaaggttta aataaaaaaa
      361 tgaattatga tgtaggagaa tctttataga taaaaagagg tggaaaggca ctattaaaga
      421 ctttaagtct aaaaaggtat caaagtatgc cagagataaa aaaatataaa tatgacactt
      481 taaaggcgat tagaaaatta aagaaatgct agaagacttt tagatgacag ttaccaagag
      541 ggtctaattt tcactgctac ttatgcagtg ggaattggac ctttttatat aagcaaattc
      601 tatttcaaaa ttggttacca agaaagactt cttttcactg ttaagtataa gagggtaatt
      661 tatagaattt tgttacatca agataaatat tttctgatgg tcaaatttta aaaagattaa
      721 taactttcga taaattttga accttaacaa ttgaatagac caagacaaga cgttaattat
      781 ttttggagcg taataaccta tccgtcaaga tctttcggct gaataattcg gcaaaaaaag
      841 ttctgctaaa caaaaagaaa gtgagcgata agtaagagtt tgaatatagg gagggatacc
      901 ctatccgcta tgaagaaaat gaggataatg atacttctaa ggttgaagcc ggctcatccg
      961 gaatagaggc ggaggtgaga ttcctatgtt gctaatccaa agcacttgtc aatgtcaaaa
     1021 aacttaatta aacaaataat tattagatat aaaactttag aggaggtata tattgaacaa
     1081 tgactggaat ggattggctg atttaatagc aaatctgatt gcaaaatatg ctggtgcttt
     1141 agatttagat aatctacccg atccaacgcc agcaaaaaat caagagatga aaaatagttt
     1201 tgacatggca aaaacacaaa ttgagacgga ctaataaaag tgttataata tacttgaaat
     1261 gatagtccaa acttaaatta aaaaaattat atatgatata gaaaaattat attgaggtta
     1321 atactatgtc aaaagaaaaa ataaaagtat acctctatac acgagtatct acgtcaatac
     1381 agatagaggg gtattcgtta ggggcacaaa aatcacgaat gaaagctttt gctatttaca
     1441 acgattatga aattgttgga gagtatgaag atgccgggaa gtctggcaag tctattgaag
     1501 gtagaataca gttcaatcga atgatggaag atataaaatc tggaaaagat ggagtatctt
     1561 ttgttcttgt gtttaagtta tcaagatttg caagaaatgc cgctgatgtt ctttctacac
     1621 ttcagataat gcaggattat ggagttaatc ttatctgcgt tgaagatggc attgattcat
     1681 ctaaagatgc tgggaaacta atgatttctg ttttatcagc tgtggctgaa atagaaagag
     1741 aaaacatccg tattcaaaca atggaaggtt gcattcaaaa agcaagggaa ggaaaatgga
     1801 atggtggctt tgctccgtat ggatataaac ttgaagacgg caagctgttt ataaatgagg
     1861 aagaggcagt tgcaataaga acgattttcg accagtatgt aaatactacg ataggagcca
     1921 atgggatatc taaatactta gagaatcatg gaattagaaa aatcccaaga cagaatggta
     1981 agaatccttt gtttgatgca ggtcttataa gaaagatatt aaagaatcct gtatataatg
     2041 ggaaaatagc atttggaaga agaactttag aaaaagttca tggtacaaga aatgaatata
     2101 agcaggttga acaagatgaa tatctaatat ctgaagggat acatgaagct atagtttccg
     2161 atgaagtttg gtaagctgct caggttaagc taaaatctca agcaaagaaa tatgagcatg
     2221 tgaataaagg aaaagataca cgcacacact tgctttctgg aattgtaaaa tgcccgatat
     2281 gtggagtggg aatgtttggg aacaagtgta tcaagaaaaa gaaagatggc acaaagtata
     2341 aagattttta ttactatggt tgtaaacata ggcagatgat aagaggtcat aagtgtacat
     2401 tcagtaagca aattagagaa gaattgttag atgatgctgt tgcagaggtg attgtcaaga
     2461 tagtaagtaa tccgaaattt gcttctatga tgcaagaaaa aatcaacatg aaggtggata
     2521 cctctgaaat agaaagagaa atagataatt accaaaagga attgagaaag agtcattcta
     2581 caaagtttaa gctaattgag gaaatagata atttagatgt tgaagataag cattataaga
     2641 gaaggaaaca ggatttagat gatagactat atcgtatgta tgacaaacta gatgaattag
     2701 aatcatcact aattgatgcg aaagcaaaga aacagactat tgaagctgaa aagcttacag
     2761 gagataacat atataaggtt ctgatctatt ttgataagct ctataaagtc atgaatgatg
     2821 tagagcgtag gcagttaatt tcagctttga tttctgaaat tcaagtttat gaagaaaaac
     2881 aatctaacgg acaatggcta aaatccatta cttttaagct accaattata gaagaaaatc
     2941 tcaacatagg tttggacaat gatgaacaag ttgaatgtgt aagtttatta gagaaacgta
     3001 gttaatcctc aaaaggttcc ccgaaccttt tgagtcccac tgacgcatca cgctgaggcg
     3061 gtatcactgc ttgtacgagt tgaagcatca gcaaagtaaa agtagatgtt cagccaatgc
     3121 gacgaggtga gaccgaaggt cgataaggtg tgttctgggt ataagactcg taaagtaagt
     3181 aggaaatatg atgagatgat acagagagcc tgaattggtc aggtgacgtg cttatttaca
     3241 ttagcctgat aatgaaaatg gagagattat cgatggttat attggaattg taccaaaatg
     3301 attattctaa agatttagta gcatttgatt ccatagaaga tgggaaagcc tttgtagctc
     3361 aaatcccggg atacactctg gaaacagaag atggttttga agtggagtat tttaatccta
     3421 aaaacatacc ggattatatg gaaattattt ttaacggaaa tattgttcct ttatctaaat
     3481 ttatgttcga tcctgaggaa aatgtaaaca ttatttggaa agagatttca aatttatccc
     3541 tcaaaaatga tagagtgatc gaaggatatt caaaaattga tgcatatgtc gttaacaacc
     3601 atgaagttaa agcctatgtc gaaacaagag aaacgaacta tcgtaaagca aaagacttct
     3661 tagaaagccg cggatatgaa atcgacagaa gctttttcgg aagtgaagac ggtgaagcga
     3721 ttctttacag aaaaaaaggg atcgaagttt ggcatttctt gtgtcactta gacccaatgt
     3781 ttgtagagat tgaagatgta gaaggatatg ttaaagaaga agttggagag attcaatagt
     3841 caaccaaagt tccttgtgag tatatacctt tgctagtaaa agagtcaaaa cgttataacg
     3901 aaggggggga agaaaaccct tgagtgtaag tctttttctt gtttagaggg aaagtattag
     3961 agtagccgct cataatttat actagatttg ataactgatt tgag
//
LOCUS       DAVKBK010000095         3976 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVKBK010000095 DAVKBK010000000
VERSION     DAVKBK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3976
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.095"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            92..1483
                     /locus_tag="VWX69_001936"
     CDS             92..1483
                     /locus_tag="VWX69_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU9193218.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            1626..2543
                     /gene="adcAII"
                     /locus_tag="VWX69_001937"
     CDS             1626..2543
                     /gene="adcAII"
                     /locus_tag="VWX69_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU9193219.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            2551..>3976
                     /gene="phtD"
                     /locus_tag="VWX69_001938"
     CDS             2551..>3976
                     /gene="phtD"
                     /locus_tag="VWX69_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU9193220.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPVQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVRDSRPEQPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEKNGVSRYIPAKNLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         1202 a          743 c          836 g         1195 t
ORIGIN      
        1 tcagattttt ttagaaaaac attttataaa tattcacata tctcctatat ttatggtaaa
       61 atagaatcat cagtttattt tggagtcaaa gatgaatata tttagaacaa agaatgttag
      121 tttagataaa acagagatgc ataggcattt gaagttatgg gatttgattt tgctgggtat
      181 cggagccatg gtagggacag gcgtctttac aatcacaggt actgcagctg caacacttgc
      241 tggcccagcc ctagtgattt caatcgttat ttctgccttg tgtgtgggat tatcagccct
      301 cttttttgca gaatttgcct cgcgagtacc cgctacagga ggtgcctata gttacctcta
      361 tgctatctta ggagaattcc ctgcctggtt ggctggttgg ttaaccatga tggagttcat
      421 gacagccata tcaggcgtag cttcgggttg ggcagcttat tttaaaggct tgctctctca
      481 atacgggata gcctttcctc aggctttaaa tggtaccttt aatcctcaag cagggacatt
      541 tgttgattta ttgcctattc ttgtcttggt cttggtgact tcgcttgttt tactaaatgc
      601 caaggcagcc ttacgcttta attcgattct agttattttg aaattttccg ctttagctct
      661 ctttgtttta gtaggaattt ggaatattaa gtttgataat tggagcaatt ttgctcctta
      721 cggttttgga caaatctatg gagctagcac tggtattatg gctggtgcgt ccttgatgtt
      781 cttcggtttt ttgggatttg aatccatctc tatggctgta gatgaagtca agactcctca
      841 aaaaaatatt cctagaggga ttgtcttatc gctttctatc gtaaccattc tctatgcctt
      901 ggtgaccctt gttttgactg gtgtggttca ctatagtcat ttaaatgtcg atgatgccgt
      961 tgcctttgcc cttcgtagtg ttgggattag ttgggcagcc aactatgtgt cattagtggc
     1021 tatcttgacc ttgattacag tttgtatttc gatgacctat gccctatcgc gtatgattta
     1081 cagtttagca cgtgacggct tagtgcctgc tgcctttaag gaactgacga agactagcaa
     1141 gataccaaag aatgctacta tcttgacagg tctagcttca gcagtagcag caggaatgtt
     1201 cccactagcc agtattgcag cctttttaaa tatttgtacc ttagcctact tgatcatgtt
     1261 ggcttatggt ctgattcgct tacggaaaga aaaaggaatg cccaaagctg gggaatttaa
     1321 aacaccattg gtacctctgt taccaatttt atcgatcatc atttgtttat ccttcatgtt
     1381 acagtataat atgaatacct ggattgcttt cctagttgcg ttgttagtag gaagtattat
     1441 ttacttcact tatggctata agcattctac catagaagaa taaagtgaaa gtctattgag
     1501 ttgttgacac tcagcagatt tttatatgtg aaagaaattt caaatttttt ctaaaaatat
     1561 cttgacagat taaattttca ggagtagaat atttactagt taattaaatg gttaaggagt
     1621 tgttcatgaa gaaacaaaat ttatttttag tcctgttaag tgtctttctt ttgtgcttgg
     1681 gggcttgtgg tcaaaaggaa agtcagacag gaaaggggat gaaaattgtg accagttttt
     1741 atcctatcta cgctatggtt aaggaagtat ctggtgactt gaatgatgtt cggatgattc
     1801 agtcaagtag tggtattcac tcctttgaac cttcggcaaa tgatatcgca gccatctatg
     1861 atgcagatgt ctttgtttac cattctcata cactcgaatc ttgggcagga agtctggatc
     1921 caaatctaaa aaaatccaaa gtgaaggtct tagaggcttc tgagggaatg accttggaac
     1981 gtgtccctgg actagaggat gtggaagcag gggatggagt tgatgaaaaa acgctctatg
     2041 accctcacac atggctagat cctgaaaaag ctggagaaga agcccaaatt atcgctgata
     2101 aactttcaga ggtggatagt gagcataaag agacttatca aaaaaatgcg caagccttta
     2161 tcaaaaaagc tcaggaattg actaagaaat tccaaccaaa atttgaaaaa gcgactcaga
     2221 aaacatttgt aacacaacat acagcctttt cttatctagc gaagagattt gggcttaatc
     2281 aacttggtat tgcaggtatc tctcctgaac aagaaccaag tccacgacaa ctaacagaaa
     2341 ttcaggaatt tgttaagacc tataaggtta aaacgatttt tacagaaagt aacgcttctt
     2401 caaaagtagc tgaaactctt gtcaaatcaa caggtgtggg tcttaaaact ctgaatcctt
     2461 tagagtcaga cccacaaaat gacaagacct atttagaaaa tcttgaagaa aatatgagta
     2521 ttctagcaga agaattaaag tgaggaaaga atgaaaatca ataaaaaata tctagcaggt
     2581 tcagtggcag tccttgccct aagtgtttgt tcctatgaac ttggtcgtca ccaagctggt
     2641 caggttaaga aagagtctaa tcgagtttct tatatagatg gtgatcaggc tggtcaaaag
     2701 gcagaaaatt tgacaccaga tgaagtcagt aagagagagg ggatcaacgc cgaacaaatt
     2761 gttatcaaga ttacggatca aggttatgtg acctctcatg gagaccatta tcattactat
     2821 aatggcaagg ttccttatga tgccatcatc agtgaagaac ttctcatgaa agatccgaat
     2881 tatcagttga aggattcaga cattgtcaat gaaatcaagg gtggctatgt gattaaggta
     2941 gacggaaaat actatgttta ccttaaagat gcggcccatg cggacaatat tcggacaaaa
     3001 gaagagatta aacgtcagaa gcaggaacgc agtcataatc ataactcaag agcagataat
     3061 gctgttgctg cagccagagc ccagggacgc tacaccacag atgatggtta tatctttaat
     3121 gcttctgata tcattgagga cacgggtgat gcttatatcg ttcctcacgg cgaccattac
     3181 cattacattc ctaagaatga gttatcagct agcgagttag ctgctgcaga agcctattgg
     3241 aatgggaagc agggatctcg tccttcttca agttctagtt ataatgcaaa tccagttcaa
     3301 ccaagattgt cagagaacca caatctgact gtcactccaa cttatcatca aaatcaaggg
     3361 gaaaacattt caagcctttt acgtgaattg tatgctaaac ccttatcaga acgccatgtg
     3421 gaatctgatg gccttatttt cgacccagcg caaatcacaa gtcgaaccgc cagaggtgta
     3481 gctgtccctc atggtaacca ttaccacttt atcccttatg aacaaatgtc tgaattggaa
     3541 aaacgaattg ctcgtattat tccccttcgt tatcgttcaa accattgggt acgagattca
     3601 agaccagaac aaccaagtcc acaatcgact ccagaaccta gtccaagtcc gcaacctgca
     3661 ccaaatcctc aaccagctcc aagcaatcca attgatgaga aattggtcaa agaagctgtt
     3721 cgaaaagtag gcgatggtta tgtctttgag aagaatggag tttctcgtta tatcccagcc
     3781 aagaatcttt cagcagaaac agcagcaggc attgatagca aactggccaa gcaggaaagt
     3841 ttatctcata agctaggagc taagaaaact gacctcccat ctagtgatag agaattttac
     3901 aataaggctt atgacttact agcaagaatt caccaagatt tacttgataa taaaggtcga
     3961 caagttgatt ttgagg
//
LOCUS       DAVKBK010000096         3703 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVKBK010000096 DAVKBK010000000
VERSION     DAVKBK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3703
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.096"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            155..382
                     /locus_tag="VWX69_001939"
     CDS             155..382
                     /locus_tag="VWX69_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193221.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            670..3552
                     /gene="nanA"
                     /locus_tag="VWX69_001940"
     CDS             670..3552
                     /gene="nanA"
                     /locus_tag="VWX69_001940"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU9193222.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKISRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYGNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQKIIGIAKGSIESM
                     HNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTK
                     EDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1263 a          622 c          835 g          983 t
ORIGIN      
        1 ttaaaaatga ggtataataa atttactaac gcttataaaa agtgatagaa tctatcttta
       61 tgtatattta aagatagatt gctgtaaaaa tagtagtagc tatgcgaaat aacagataga
      121 gagaagggat tgaagcttag aaaaggggaa taatatgata tttaaggcat tcaagacaaa
      181 aaagcagaga aaaagacaag ttgaactact tttgacagtt tttttcgaca gttttctgat
      241 tgatttattt cttcacttat ttgggattgt cccctttaag ctggataaga ttctgattgt
      301 gagcttgatt atatttccca ttatttctac aagtatttat gcttatgaaa agctatttga
      361 aaaagtgttc gataaggatt gagcaggaag tatggtgtaa atagcatagg ctgatgtcca
      421 tcatttgctt ataaagagat attttagttt aattgcagcg gtgtcctggt agataaacta
      481 gattggcagg agtctgattg gagaaaggag aggggaaatt tggcaccaat ttgagatagt
      541 ttgtttagtt catttttgtc atttaaatga actgtagtaa aagaaagtta ataaaagaca
      601 aactaagtgc attttctgga gtaaatgtct tatttcagaa atcgggatat agatatagag
      661 aggatcagta tgaatcggag tgttcaagaa cgtaagtgtc gttatagcat taggaaacta
      721 tcggtaggag cggtttctat gattgtagga gcagtggtat ttggaacgtc tcctgtttta
      781 gctcaagaag gggcaagtga gcaacctctg gcaaatgaaa ctcaactttc gggggggagc
      841 tcaaccctaa ctgatacaga aaagagccag ccttcttcag agactgaact ttctggcaat
      901 aagcaagaac aagaaaggaa agataagcaa gaagaaaaaa tttcaagaga ttactatgca
      961 cgagatttgg aaaatgtcga aacagtgata gaaaaagaag atgttgaaac caatgcttca
     1021 aatggtcaga gagttgattt atcaagtgaa ctagataaac taaagaaact tgaaaacgca
     1081 acagttcaca tggagtttaa gccagatgcc aaggctccag cattctataa tctcttttct
     1141 gtgtcaagtg ctactaaaaa agatgagtac ttcactatgg cagtttacaa taatactgct
     1201 actctagagg ggcgtggttc ggatgggaaa cagttttacg gtaattacaa cgatgcaccc
     1261 ttaaaagtta aaccaggtca gtggaattct gtgactttca cagttgaaaa accgacacca
     1321 gaactaccta aaggccgagt gcgcctctac gtaaacgggg tattatctcg aacaagtctg
     1381 aaatctggca atttcattaa agatatgcca gatgtaacgc atgtacaaat cggagcaacc
     1441 aagcgtgcca acaatacggt ttgggggtca aatctacaga ttcggaatct cactgtgtat
     1501 aatcgtgctt taacaccaga agaggtacaa aaacgtagtc aactttttaa acgctcagat
     1561 ttagaaaaaa aactacctga aggagcggct ttaacagaga aaacggacat attcgaaagc
     1621 gggcgtaacg gtaaaccaaa taaagatgga atcaagagtt atcgtattcc agcacttctc
     1681 aagacagata aaggaacttt gatcgcaggt gcagatgaac gccgtctcca ttcgagtgac
     1741 tggggtgata tcggtatggt catcagacgt agtgaagata atggtaaaac ttggggtgac
     1801 cgagtaacca ttaccaactt acgtgacaat ccaaaagctt ctgacccatc gatcggttca
     1861 ccagtgaata tcgatatggt gttggttcaa gatcctgaaa ccaaacgaat cttttctatc
     1921 tatgacatgt tcccagaagg gaagggaatc tttggaatgt cttcacaaaa agaagaagcc
     1981 tacaaaaaaa tcgatggaaa aacctatcaa atcctctatc gtgaaggaga aaagggagct
     2041 tataccattc gagaaaatgg tactgtctat acaccagatg gtaaggcgac agactatcgc
     2101 gttgttgtag atcctgttaa accagcctat agcgacaagg gtgatctata caagggtaac
     2161 caattactag gcaatatcta cttcacaaca aacaaaactt ctccatttag aattgccaag
     2221 gatagctatc tatggatgtc ctacagtgat gacgacggga agacatggtc agcgcctcaa
     2281 gatattactc cgatggtcaa agccgattgg atgaaattct tgggtgtagg tcctggaaca
     2341 ggaattgtac ttcggaatgg gcctcacaag ggacggattt tgataccggt ttatacgact
     2401 aataatgtat ctcacttaaa tggctcgcaa tcttctcgtg tcatctattc agatgatcat
     2461 ggaaaaactt ggcatgctgg agaagcggtc aacgataacc gccaggtaga cggtcaaaag
     2521 atccactctt ctacgatgaa caatagacgt gcgcaaaata cagaatcaac ggtggtacaa
     2581 ctaaacaatg gagatgttaa actctttatg cgtggtttga ctggagatct tcaggttgct
     2641 acaagtaaag acggaggagt gacttgggag aaggatatca aacgttatcc acaggttaaa
     2701 gatgtctatg ttcaaatgtc tgctatccat acgatgcata atggaaaaga atacattatc
     2761 ctcagcaatg caggtggacc gaatcgtgaa aatgggatgg tccacttggc acgtgtcgaa
     2821 gaaaatggtg agttgacttg gctcaaacac aatccaattc aaaaaggaga gtttgcctat
     2881 aattcgctcc aagaattagg aaatggggag tatggcatct tgtatgaaca tactgaaaaa
     2941 ggacaaaatg cctataccct atcatttaga aaatttaatt gggaattttt gagcaaagat
     3001 ctgatttctc ctaccgaagc gaaagtgaag cgaactagag agatgggcaa aggagttatt
     3061 ggcttggagt ttgactcaga agtattggtc aacaaggctc caacccttca attggcaaat
     3121 ggtaaaacag cgactttcct aacccagtat gatagcaaga ccttgttgtt tgcagtagat
     3181 aaggaagata tcggacagaa aattattggt atagctaaag gaagcatcga aagtatgcat
     3241 aatcttcctg taaatctagc aggtgccaga gttcctggcg gagtaaatgg tagcaaagca
     3301 gcggtgcatg aagttccaga atttacaggg ggagttaatg gtacagagcc agctgttcat
     3361 gaaatcgcag agtataaggg atctgattcg cttgtaactc ttactacaaa agaagattat
     3421 acttacaaag ctcctcttgc tcagcaggca cttcctgaaa caggaaacaa ggagagtgac
     3481 ctcctagctt cactaggact aacagctttc ttccttggtc tgtttacgct agggaaaaag
     3541 agagaacaat aagagaagaa ttctaaacat ttgattttgt aaaaatagaa ggagatagca
     3601 ggttttcaag cctgctatct ttttttgatg acattcaggc tgatacgaaa tcataagagg
     3661 tctgaaacta ctttcagagt agtctgttct ataaaatata gta
//
LOCUS       DAVKBK010000097         3612 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVKBK010000097 DAVKBK010000000
VERSION     DAVKBK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.097"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(189..800)
                     /gene="rpsD"
                     /locus_tag="VWX69_001941"
     CDS             complement(189..800)
                     /gene="rpsD"
                     /locus_tag="VWX69_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU9193223.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(995..2047)
                     /locus_tag="VWX69_001942"
     CDS             complement(995..2047)
                     /locus_tag="VWX69_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9193224.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2044..2742)
                     /locus_tag="VWX69_001943"
     CDS             complement(2044..2742)
                     /locus_tag="VWX69_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9193225.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGCETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2909..>3612)
                     /locus_tag="VWX69_001944"
     CDS             complement(2909..>3612)
                     /locus_tag="VWX69_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEU9193226.1"
                     /translation="EKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDN
                     GEAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRANGTQTYSATVNVY
                     GNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDS
                     MPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALA
                     GLLGGLGLKNKKEEN"
BASE COUNT          988 a          810 c          704 g         1110 t
ORIGIN      
        1 cataaaaaga ttataccaca ttgtgtacta tttttggttc actttactat atcactttgg
       61 actatatcgg tctagttatg tctaaacgat tatagctgga tactaagaga aatcaaaaaa
      121 gcactaaggg agaacgtccc aaagtgctta atatcaaggc ctcaaagcct atcttattta
      181 ataaaatatt acaacatttt gttgtagaat tcaacgacaa gtgcttcgtt gatttctggg
      241 ttgatttcgt cgcgttctgg caagcgagtc aatgaacctt ccaacttttc agcgtcgaat
      301 gatacgaatg ctggacgtcc aagagtagct tctactgctt caaggattgc tggaactttc
      361 aatgattttt cacgaactga gatcacttga cctggagtta cgcggtatga tgggatatca
      421 acgcgtttcc cgtcaacaag gatgtgaccg tggtttacga attgacgagc ttgacgacga
      481 gtagtcgcga gaccaagacg gtaaacaaca ttatccaaac gacgttccaa aagaagcata
      541 aagttgaaac ctaggattcc acctttgatt tttgtagctt gtacgaacaa gttacggaat
      601 tgtttttcac ctacaccgta agtgaaacga agtttttgtt tttcagccaa ttgcaaacca
      661 tattctgaca atttagaacg gttgtttggt ccgtgttgtc ctggtacata gttacgacgt
      721 gccaattctt tacctgtacc tgtaagtgaa aggccaaggc gacgagcttg tttccaagat
      781 ggtcctgtat aacgtgacat atgaatgtcc tcctgatata aataatattt cggtggaaat
      841 agtcacttag aaagccctga ttcgtgcaga tgcccttcgc ctaaacagcc aaggttactt
      901 gtcataagac acctgttgac gagcttcatg ctttcctgct gatatttcac actaaattca
      961 ttttaccatg aatagctgga tttgtaaagg ggttttaggc tttattttca ctaccagaga
     1021 ggttgagaac gagggtaaag gtacttccta gaccgtactg gctgctgact gtgatttccc
     1081 cacccaattg atgggccaat tcacgcgcaa tcgcaagtcc taatccatga ccacctgtct
     1141 tcatgttacg cgaagtttcg acacgataaa ggcgtttgaa aatattttcc aaatcctctg
     1201 gggcaatacc ctgcccttca tcggtcacac tgattgaaag ctggtccttc tccagcttag
     1261 ccaccacttc cagcttggtt cctggagcag aatatttaaa agcgttatcg accagattca
     1321 ccaagatacg agaaagctta gcataatctc cctcaatccg ggcagactct gggattacct
     1381 gcaagtggac atctcttctc tcctgctcaa tcaaaaactg aaattcactc atgcactcaa
     1441 ttaagagctt gtccagaaaa atactgtctt tactggtagt ttccacctga tttctagctg
     1501 tgtttagggt caaaaaattc aactcctcaa ccagtttatt gagcctctcc gtctggcgtc
     1561 caatggttgc tagataatga gcttgctccg actccttgat aataccatcc aaaatccctt
     1621 ctaccgtcgc ttggatcgaa gtgataggag tcttaatatc atgcgacaac tgggcaatca
     1681 tcaagccctt ttctcgttcg ctttcttcca aggaatcaaa gcttacctgc aaatcatggg
     1741 acatctcatt aaaagtttgc cctaattgct gaaattctac aggaccttga acctccaaat
     1801 ttgaaggaaa atccttggcc gctacccgct tggcatgctc cttgagtttg cccaacgacg
     1861 taaagactgg caataggaga aagagactaa tcccagcacc gacaaggctg gcaacgatgg
     1921 tcatcccaag caaaaagtaa atctcgcctt tcgcaatcag cattttttga acagcccaaa
     1981 aaacaaccaa aatggttaag agggttgaaa taatatatcc aaccaaaata taacttttta
     2041 gtttcatgtt tgtcctctcg gtttctctat cttatatccc aacccccaaa ctgtcttaat
     2101 agtgggcgtt tggtcactac tatattttgc cagctcctgt cgaagagcat ggatatgcac
     2161 attcaaggta ttggtgtcat ccacgtagtc ttctttccag atcttttcat agaggtctgt
     2221 cttggagaaa actcgctctg gattgctagc taaaatccac agcaattcaa atgatttaac
     2281 agttaaatcc agcatttctt ctcctatttg aacttcatga ctactatgat tcatttttag
     2341 attgccaagg gaaatcagct ctgtttcgca cccacgatga aggcggcgca aaatattgtg
     2401 gacacgcaaa actagctcac gtgggctaaa aggcttagca ataaaatcat ctgctcccaa
     2461 gctcaggccg taaatcttgt cctgttcact ggtcttagca gtaataaata ggaaaggctg
     2521 ctctggtgat aagtattgaa cctcactgat taaatcataa ccatccatcc gaggcatcat
     2581 gacatctgtg ataatcaaat caatcggttt tttcttgaac agctctagcg cttccagtcc
     2641 atcatgggct accaagacct gataacctgc ctgaattaag tatctctgat gaatatctgt
     2701 gatttctacc tcgtcgtcaa cgagtaaaat tgtctttccc atctgtctct cctttgataa
     2761 aaacagtgct atactgcttt aagtataaca ctatttttat tgttttacga tgattttaat
     2821 ctgctattga aagaaagtcc tgattgctga ttgagttgtt aaactaatct tagtcagccc
     2881 actatccatc atttatttcc ttagctgatt agttttcttc ttttttgttt ttcaaaccta
     2941 gaccaccgag taaacctgca agcgcaagcc caaggaaacc aatacttgcc attgatgttt
     3001 gagtctcacc agtatttggt agcatagctt tatcctctga catcatcgta tcagacatct
     3061 tgttagcaga agcagccatg ttttcacctg ccatcgtgtt ggtagaactt gtcatggtgt
     3121 cagcaggcat gctatctgta gtacctgtag catgattgtg attcatcgga gtcacgccag
     3181 aaccagagtt agaaggtgat aatgaaccat ttgctgtgtc tgatgtttct ttaacattta
     3241 tcttaatagt gactttttta gttgctacga tgttgtccaa gtctggttta ccgtctttgt
     3301 taccatagac attgactgta gcgctgtaag tttgagtacc gtttgctcgg aactggtcaa
     3361 tgagcgcttg tttttctttg ccagctacat ttccgtccaa ggctacttga tagaagtatt
     3421 gacctttggt cttcacgttt tcgcctagtg gagatagggc tgggttttta gcctcaccgt
     3481 tatctgacca tggtgccttg tcagatgcct tgagcaagag acgagtcaac atgccatcac
     3541 ctgcgaagag ttcgtatgga atcacatggt tgacacctgc tgtgaatgga ccttcaccct
     3601 tggctttttc ta
//
LOCUS       DAVKBK010000098         3534 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVKBK010000098 DAVKBK010000000
VERSION     DAVKBK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3534
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.098"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            96..434
                     /locus_tag="VWX69_001945"
     CDS             96..434
                     /locus_tag="VWX69_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193227.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDVR
                     LNAYWDYYRF"
     gene            500..2482
                     /locus_tag="VWX69_001946"
     CDS             500..2482
                     /locus_tag="VWX69_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9193228.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFMMTITMVILFTFLMTGQIE
                     LLYIGAASLLVLMLSIIMSFRKLSESYTKILKGDES"
     gene            2479..3102
                     /locus_tag="VWX69_001947"
     CDS             2479..3102
                     /locus_tag="VWX69_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9193229.1"
                     /translation="MTIDLLNVSKSFGSKKIFTDLNLIFESGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGNVLVDKQDIWKIKERTFFKNTVGYVFQNYSLIDNKTVYDNLSLIT
                     KDKKTITDVLEKVGLSSDYLHQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIIRLLLNETAEDKYVIIATHDPAVYNEVDVIIDMKDIGYKV"
     gene            3099..>3534
                     /locus_tag="VWX69_001948"
     CDS             3099..>3534
                     /locus_tag="VWX69_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193230.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKEELNS"
BASE COUNT         1279 a          466 c          636 g         1153 t
ORIGIN      
        1 taaatataat caattcatat taaagtaata tggagggact aaaaagagac tattatttaa
       61 tcttcatcaa atatttaaat tcaaggagaa gtaaaatgaa aaaaagaatt aataagaaag
      121 catctgtttt tctagttgca agtgttttca gttttagctt tgctactaca gctagtgtcg
      181 ttaacgcagt aacggcacac cctgctccaa gtcccattat tgatgtatgg gaatatggtg
      241 taaatgataa ctatggttat tcgaattact ttgttagttc tccaagtaat attggatcaa
      301 aatcttcagt aacgaatttt tggggaacag ttaaagctca ggataaaaaa gattatggat
      361 gggcatattc aagtgcaaca aaatcttgga acgatgttcg cttaaatgca tattgggatt
      421 attatagatt ttaaaaataa tttatgaaaa caagagaccc aattataaga ttgggtctct
      481 tgtaatatgg taattgctta tgaaattaaa attatgtatc attggattct tcttttgttt
      541 gattgctaca attggtctgg tcactattag tgataccgaa atccccatac ctttaccaat
      601 tgatggagct ttttctatcc aaggaaaaag taatctttct aataacgaaa tatacgaaat
      661 ggttcgtgac ttatcaaaaa cggaaaaggt taccatttac aagccaatcg ttcagagttc
      721 gggtcagttg aagtatgtaa attttgatga tgtaaataat gaacaattaa agtcagcacc
      781 aatagtaggg atgtattaca cacttgggaa aatggatgta gacagtttga aaccacttac
      841 gatgacggga ctacaaacag tctatatggc ttatccttgg tatataggag gaatattaca
      901 attcactgga actttaagaa tactgttaat gggttcaatt tatttaactt tattagttgt
      961 tttatttgtt gttaggacga ggcagatcaa agaaggagtg atacgacgtt ctttgggctt
     1021 gcctatatac gacttaagaa gagagtatgg catttctctt atttttgaac tgattatgat
     1081 ggctttattg atgatttctt acagttcttt tttgggtaat ggtttcttca cctatagttc
     1141 taagttattt ttctctctgc ttttaacgaa ttttatacta tttcaaatca ttgatcttat
     1201 tacttttgtt ttattttggt tgacgattca gattgaaaag cctattgaaa ttattaaaaa
     1261 caaggcaaaa aacaagctta tttttgtcgt atggcttgct attatttcga ttatcatcct
     1321 tgtctcagga gtttttttac aagaaacaaa gagtagtcaa tctagtatta acatacagat
     1381 acagaattta gtaccatggg atacagtaaa agactggaga aggattgagt tccttggaat
     1441 tgaaagtaac tctactaaaa atagagaagt taatgattca gatggtcagt atctacagat
     1501 agttgctgcc ttaaaaaact tagatttctt atatatagaa cggtcttcag catatgttcc
     1561 agatttcatg aaaacttcac atgttataga aaatttttct aaacaattag aaaatgacgg
     1621 gataacgaat ccagaaataa ataaagagtt aatttatatc aaccaaacag gtgctaacct
     1681 acaaaataaa gtgaatggaa caaactatca tcttttagat aataagatag caaccatcta
     1741 tattcctgag aagtggaaag aaaaccagaa atctattgag aatacagttg tagcagaaca
     1801 atttattgga acaaactata caagagaaca gcttgcagtt caaataattc ctgatgggga
     1861 aaaaattttt tattttaatg aggatgctga taataatctt aaaatgaaag atattttacc
     1921 gctggcaaat gtagcagata gcaaagataa tatagttgtt gtgttagata cggacaaaat
     1981 gatggaaaat aataagtttt ctttggctag taacatacta tataaatctc tttttagtcc
     2041 tgaagcggta aaaaaaataa atgagatgac tgtcctgttg aatttctcaa tgaatccagt
     2101 agatgtttac caaattgtga aattaaagat tcaatcctta gagcaccaaa ttttactttc
     2161 acaaatcttg cagaagataa tttacagtat tgtctttata ctcatttatc aatatgtcca
     2221 actttttatt actctaaaac agaatgaata tgtgaaaaaa atcattttgg gtctgtcaaa
     2281 aacatatata gcaatttcaa gtctcaaata ttttatgatg actattacaa tggttattct
     2341 atttacattt cttatgacag ggcaaataga gttgctatat attggagcgg cttctctgct
     2401 agttttgatg ttgtcaatca taatgagttt tagaaaatta tctgaaagct acactaaaat
     2461 tttaaaagga gatgaatcat gacaattgac cttttgaacg tttcaaaaag tttcggctca
     2521 aagaagatct ttacagactt aaatttaata tttgaatctg gaaaaagcta tgcattgatt
     2581 ggaggttctg gctccggtaa aagtaccctt cttaatatta taggaagatt agaaaaaatt
     2641 gacagtggga atgttttagt tgataaacaa gatatttgga agataaaaga aagaactttt
     2701 tttaaaaata ctgttggata tgtatttcag aattattctt taatagataa caaaacagtg
     2761 tatgataatc tgagccttat cactaaagac aaaaaaacaa taactgacgt acttgaaaaa
     2821 gtaggactgt caagtgacta tttacaccaa aaaatatatg aattgtctgg agggcaggct
     2881 caacgtgtag ctattgccag aatgttaatg aaaccacgta aaattatctt agcagatgaa
     2941 cctacaggag ctttagatgg tgagattgga aaagaaatta ttcgtttact attgaatgaa
     3001 acagctgaag ataaatatgt cattatagcg acacatgatc cagctgtcta taacgaagtt
     3061 gatgtgataa ttgacatgaa agatataggg tataaggtat gaaaaagaaa atttatattg
     3121 ctttgatctt tgtaactggg gtactcgcca ttttcttttt tggaaaacaa atgattacaa
     3181 aagaaaatat caataagcca acggtagagt taacaatcta tacgctttct tctagtgata
     3241 cagaaaaatg gaataaagtg agacaagtag aaacggaaga agctatatac ttcataactg
     3301 tgaaagaagt atcatcttca gaagaagtat tttcaaacat cattgcaaat ggagctgcta
     3361 cggggttcgg agttcgtgaa gaagaagtga agaaattcaa taatggttta ggagacacca
     3421 tagaggactc taagcataat aaactaattg aaatagaatt ttttactttt tctgatgatg
     3481 gcgcgggatt tgtggtagca aactttgact acggtaaaga agagttgaat tctc
//
LOCUS       DAVKBK010000099         3433 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVKBK010000099 DAVKBK010000000
VERSION     DAVKBK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.099"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1262..1765
                     /locus_tag="VWX69_001949"
     CDS             1262..1765
                     /locus_tag="VWX69_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193231.1"
                     /translation="MKLLDCILDYQERFNRKACQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLYEFIGDIFYFKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            2051..>3433
                     /locus_tag="VWX69_001950"
     CDS             2051..>3433
                     /locus_tag="VWX69_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEU9193232.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPQVVEKSSLE
                     KKYEEAKAKADTAKKDYETAKKKAEDAQKKYDEDQKKTEEKAKKAEEAAKEVDDASLA
                     VQKAYVEQRKAQEEKNKHSGNPEYAKKLAEADKKITEETTKLTDAQTKFQSVQAMVVP
                     EPEQLAETKKKAEEAKAEEKVAKRKYDYATLKVVLAKKEVEAKELEIEKLQYEISTLE
                     QEVATAQHQVDNLKKLLAGADPDDGTEVIEAKLKKGEAELNAKQAELAKKQTELEKLL
                     DSLDPEGKTQDELDKEAEEAELDKKADELQNKVADLEKEISNLEILLGGADPEDDTAA
                     LQNKLATKKAELAKKQTELEKLLDSLDPEGKTQDELDKEAAEAELDKKVEALQNKVAD
                     LEKEISNLEILLGGADSEDDTAALQNKLATKKAELEKTQKELDAALNELGPDGDEEET
                     PAPAPQPEQPA"
BASE COUNT         1280 a          463 c          682 g         1008 t
ORIGIN      
        1 atttttagga tatcttttag tgattcaaaa agcaggctat ttgttttcgg ttttacttct
       61 tttttctaat ttttcagttc catttatcaa agaaaaggaa ttcgaattat ttaaaaatag
      121 caagtaatag aaacataggt taaatcttag aacggcttaa aatcagatat gataaaggga
      181 aatagtctta tctaggtaac taagtgctac aaacacagtc gaggatcact tgttaggatt
      241 acattttaat catgcttaat aagaatggag aattcctatg gggattgtat tactctgaag
      301 tttcgaatac cttagttctc gtgattttga gctgttctag ctttagaatc cttcagaacg
      361 taaaatttta agcagtcaaa gacttagaat agcctggaaa catttatttt atagcaattc
      421 taaacttaga attgctcata tatatgtatt tgagctgctc gatagttagg acagctctat
      481 tctgagaaat ctgagctatc aatgcttcag aatagtattt cgccaatggt ttttattgaa
      541 gaggtgattg tgttatgata gtctaaaata aaattgattt aatagagtaa atggagaatc
      601 gttacatgaa acattttttt gcaggaattg gtgagataaa acttgttggc tacttattgt
      661 atatatgtgt aggactagcc cctctttttc atatatatgt cataggttcg gaactgagtt
      721 ttgtgaaaat agtgttatct attttgggag ttatatttgt aagtatgtta actattgctc
      781 gaatttatcg gacttttcta taaagaatag tttggacttg aactgtatct aaaaacagag
      841 gttggtcgat tatcagcctc tttcttgtcg ttgaaaagag tgagatatat tgacttttga
      901 aaaaaagatg tcataattga gttgggataa acctaaaagt aatatagtag attgaatctg
      961 gaatagtccg ttatgactgt taaaatattt ctagaaatta atttgacttt cctaatcgat
     1021 ttgttcacat cttgtttcaa tctactatac tttctcgtta aaccgttcgg caattcatgg
     1081 tgacatggac acatagtagt aagcacacta tgtggcttgg cagagctaaa aactgttccc
     1141 ttgcgataag cctaataagc acaacatagg gagttagaga agccgactct aatcaaccac
     1201 tttgggcagt agtgagaact gccccgtgct tttttatttt gagaaaatat ggagtttgtc
     1261 gttgaaatta cttgattgta ttttggatta tcaagaaaga ttcaatagaa aagcatgtca
     1321 agtatcaacg aattataagt atttagagac tttcaaagtg aatttttgcc tgactgattt
     1381 acatcattta tttggcttac acaaaatcac acgagattat gctagtcaaa caaaacctgc
     1441 tattcaagct ggtgttttta ttttagaaga ttttagaaat atcctattgt acaatgatgt
     1501 aatcgaaagg atatctttat atgagtttat aggtgatatt ttctatttta aaataacaag
     1561 ttgttgcatc gtagctaagg atttatctaa aaatactatg aaattggacg tcatattttt
     1621 tgaggataaa aataaaagat ccgcagtttt aggtttacga agagacaaaa gcggagtatt
     1681 taaaccagtt actctacatt ttacaagcgc taagaaatat gctaaagttc gtaaaacaga
     1741 tgtgaaagaa atgaaatggc tataaagatt gtccgcaggc ttaagcttgc gttttttgtt
     1801 gtttaacgaa attaaaaaac aagctctctc atcggaaatg tttttatagg aatgaaggaa
     1861 gatgatgcta tgtttaaaaa gagaatcgaa aagggcaaaa gtagtgtctt tatctttttg
     1921 gagtagaagc ttatgatata gaaatttgta ataaaaatgt aatataaaac atttgacaaa
     1981 tatttacggg gggagtatac ttaatataag tatagtctaa aaatgactat cagaaaagag
     2041 gtaaatttag atgaataaga aaaaaatgat tttaacaagt ctagccagcg tcgctatctt
     2101 aggggctggt tttgttacgt ctcagcctac ttttgtaaga gcagaagaag ctccacaagt
     2161 tgtcgaaaaa tcttcattag agaagaaata tgaggaagca aaagcaaaag ctgatactgc
     2221 caagaaagat tacgaaacgg ctaaaaagaa agcagaagac gctcagaaga aatatgatga
     2281 ggatcagaag aaaactgaag agaaagcgaa aaaagcagaa gaagctgcta aggaagtaga
     2341 tgatgctagt ttagcggtgc aaaaagctta tgtggaacaa agaaaagcac aagaagaaaa
     2401 aaataaacat tcaggaaatc cagagtacgc taaaaaatta gcagaagcag ataaaaaaat
     2461 aactgaggag acgactaaac taaccgatgc tcagacaaaa tttcaatctg ttcaagcaat
     2521 ggtagttcct gagccagagc agttggctga gactaagaaa aaagcagaag aagctaaagc
     2581 agaagaaaaa gtagctaaga gaaaatatga ttatgcaact ctaaaggtag tactagcgaa
     2641 gaaagaagta gaggctaagg aacttgaaat tgaaaaactt caatatgaaa tttctacttt
     2701 ggaacaagaa gttgctactg ctcaacatca agtagataat ttgaaaaaac ttcttgctgg
     2761 tgcggatcct gatgatggca cagaagttat agaagctaaa ttaaaaaaag gagaagctga
     2821 gctaaacgct aaacaagctg agttagcaaa aaaacaaaca gaacttgaaa aacttcttga
     2881 cagccttgat cctgaaggta agactcagga tgaattagat aaagaagcag aagaagctga
     2941 gttggataaa aaagctgatg aacttcaaaa taaagttgct gatttagaaa aagaaattag
     3001 taaccttgaa atattacttg gaggggctga tcctgaagat gatactgctg ctcttcaaaa
     3061 taaattagct actaaaaaag ctgagttagc aaaaaaacaa acagaacttg aaaaacttct
     3121 tgacagcctt gatcctgaag gtaagactca ggatgaatta gataaagaag ctgctgaagc
     3181 tgagttggat aaaaaagttg aagctcttca aaacaaagtt gctgatttag aaaaagaaat
     3241 tagtaacctt gaaatattac ttggaggggc tgattctgaa gatgatactg ctgctcttca
     3301 aaataaatta gctactaaaa aagctgaatt ggaaaaaact caaaaagaat tagatgcagc
     3361 tcttaatgag ttaggccctg atggagatga agaagaaact ccagcgccgg ctcctcaacc
     3421 agagcaacca gct
//
LOCUS       DAVKBK010000100         3386 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVKBK010000100 DAVKBK010000000
VERSION     DAVKBK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.100"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            49..243
                     /locus_tag="VWX69_001951"
     CDS             49..243
                     /locus_tag="VWX69_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9193233.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(609..1919)
                     /locus_tag="VWX69_001952"
     CDS             complement(609..1919)
                     /locus_tag="VWX69_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU9193234.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2156..3028
                     /locus_tag="VWX69_001953"
     CDS             2156..3028
                     /locus_tag="VWX69_001953"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU9193235.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3159..>3386
                     /locus_tag="VWX69_001954"
     CDS             3159..>3386
                     /locus_tag="VWX69_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9193236.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPRKVDRDRLKNYLTDNPDAY"
BASE COUNT         1067 a          562 c          752 g         1005 t
ORIGIN      
        1 tcatttaaaa aaattttatt tttttatttt tcattacgaa taatatagat gaaggggaaa
       61 gagtatgaaa acagaactgt ttcttttgct attagttcaa aaggagaaaa aatgaaagta
      121 gaaaatattt cgtatagggt ggatcatcgt atattgtttg ataatatttc ttttgatact
      181 tcgagttcag gcgtgacatt aattactggt aaaaatggta caggaaagtc aactttacta
      241 tagtagattg aaactagaat agtacacatc tacttctaaa atattgttag aaatcgattt
      301 gactatcctg atctatttgt cctgttctta tttcatttca ctatatctca aattgagtat
      361 gacgaagtgc gctcccatgt cctgggaacg cactttcttc atatttttca tattcttgaa
      421 tccatcgata aagactattg ggatgaattt ttaaagttga actaatcatt tttacaggat
      481 gagatttaca gcagagagtt tgaaggcttt atcaaaggtt tttcttggca taatgacttt
      541 tcctcgtttc cacttaattt tgtgtctact ttattatacc aagtccaccc ttaagttaga
      601 taataaatct aacttaagga agctagaagg atgagaatcc aggtggtcaa gagtcccaaa
      661 cttaagctga tggggacacc cagaataatt tgctttttga aggcaaggcc acgttcctct
      721 atattgggaa gtgagagttg aatgagagaa ccagctgatg aaaagggtga gatattagta
      781 gatagagcgc caataacggt ggctgttgtg agtaagtgaa tatcaatctg aggattttga
      841 gcactgatga tagcaatgat gggaaagagg gctggagcta caacggatag ggtggaacta
      901 aagagtgaca tcactccggc tatcacacaa aagaacagag gtaaccagaa atgaggaatg
      961 gttgttgtca tgaggtgccc tatcagtgtg actaaacctg acttgaccgc tagagacatt
     1021 agtaagctca tgccgcagag catgataatt gtagcccagg gaaccttagc taaaatggct
     1081 tcttgcttcc ctaatttgag ccttaaggcg aggcagacca tgagtattga gacaaagcca
     1141 atatcaaatg ttttttgata agtagctatc caggcgatgt ttgggaaaat gagatgcaac
     1201 aagggaaaaa gccaaaccaa aaccatgctg ctgatcatga gcaaggtggt ttgtctttga
     1261 accttgctga ggagtggtgg ttggtcaata gtcaaggatg agtttgttct tcccttacta
     1321 tagtgactgt aacaggataa taaaagcaag acgatgagtg ggtagataat gctgacgata
     1381 aagatatgat tgccaagtga aaaagcttgc tcttcccatc ccatttgctt aaacaggcct
     1441 tgaaagacaa tgcctgagct actggttatc aaattagccc ctcctgaagc tccccaattg
     1501 acggcttgag ctccaatcaa agggtgtttg tccgcttttt gacagagggt aatcgctaga
     1561 ggacagcaaa cggccatagt agtgaaaaat ccagcaccta aagcagacaa aagggttgcc
     1621 atcaggtata aaatcatgta gagggcgtta gggtgggtgc gtgtgcggta gagaatgtgt
     1681 tgagccaaaa catcaagagt accgttagtt gttgcaacgt tataaaagag agagacgcta
     1741 aaaatggtaa aaaagagtga ggttggccaa aaatgaagaa gttctttggg gcttaatccc
     1801 atgagagtgg ttgcgatgag gtaagaaaaa gcaatagcca gcaggccaat attgattttg
     1861 gtgcggtaac caattccaat ggctagagca atggcgctaa tcattattaa atgaatcatt
     1921 gaattgtcct ttcagttaga atatggaaat aggttggcaa ttttggcgct caaaagacca
     1981 cctgtttcct attggtactt gactattata cacaaaaaaa atacaattgt cttgacaatt
     2041 gtattgacac ttgttagaat taaaaatgag gtattcaggc ttgtgatttc ctatggaagt
     2101 taatagtaat tgcctctagt gcttacaagt gatattaaaa atagaggact tagtgatgtc
     2161 aatcatttca actgatttaa ccccttttca aatagatgat acattgaaag cagccttgcg
     2221 agaagatgtt cattccgaag attacagtac caatgccatt tttgatcatc atggccaagc
     2281 caaggtgtcg ctttttgcca aggaagctgg tgttttagcg ggactaaccg tttttcaaag
     2341 ggtttttacc ctatttgatg ccgaggtgac cttccagaat cctcatcaat ttaaggatgg
     2401 ggatcgtttg actagtggcg atttggtttt agaaatcata ggctcggtga gaagtctctt
     2461 aacatgtgaa cgcgttgcct tgaatttttt acaacattta tcagggattg cttcgatgac
     2521 agctgcttat gtagaagcct taggcgatga ttgcattaag gtatttgata ctcgaaaaac
     2581 tactcctaat ttacgtcttt ttgagaaata tgccgtgaga gttggcggtg gctataatca
     2641 tcgctttaat ttatcagatg ctatcatgct aaaagacaat cacattgcgg cagtaggtag
     2701 tgttcagaag gcaattgctc aagcgcgtgc ctatgcccct tttgtgaaaa tggtcgaggt
     2761 ggaagtggaa agccttgctg ctgccgaaga agctgcggcg gcgggtgctg atattatcat
     2821 gttggataat atgtcattgg aacagattga acaggccatt accctaattg caggacgttc
     2881 tcggattgaa tgttctggaa atattgatat gaccactatt agccgttttc gtggtttagc
     2941 gattgattac gtctccagtg gtagtttaac ccatagtgct aagagtcttg atttttccat
     3001 gaagggttta acctaccttg atgtctaagt tgtaaaataa actaactttt taaaggatgt
     3061 ctttcctcta gaacgagttt tatgtcagat agtttaaacg cctcttcaaa tatagtaaaa
     3121 tgaaccaaaa atagtacaca atgtggtata atcttcttat ggcatattca atagattttc
     3181 gtaaaaaagt tctctcttat tgtgagcgaa caggtagtat aacagaagca tcacacgttt
     3241 tccaaatctc acgtaatacc atttatggct ggttaaagct aaaagagaaa acaggagagc
     3301 taaaccacca agtaaaagga acaaaaccaa gaaaggttga tagagataga cttaaaaact
     3361 atcttactga caatccagac gcttat
//
LOCUS       DAVKBK010000101         3271 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVKBK010000101 DAVKBK010000000
VERSION     DAVKBK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.101"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            29..3148
                     /gene="phtE"
                     /locus_tag="VWX69_001955"
     CDS             29..3148
                     /gene="phtE"
                     /locus_tag="VWX69_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU9193237.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1212 a          544 c          634 g          881 t
ORIGIN      
        1 cttcatcatt tattgaaatg agggatttat gaaatttagt aaaaaatata tagcagctgg
       61 atcagctgtt atcgtatcct tgagtctatg tgcctatgca ctaaaccagc atcgttcgca
      121 ggaaaataag gacaataatc gtgtctctta tgtggatggc agccagtcaa gtcagaaaag
      181 tgaaaacttg acaccagacc aggttagcca gaaagaagga attcaggctg agcaaattgt
      241 aatcaaaatt acagatcagg gctatgtaac gtcacacggt gaccactatc attactataa
      301 tgggaaagtt ccttatgatg ccctctttag tgaagaactc ttgatgaagg atccaaacta
      361 tcaacttaaa gacgctgata ttgtcaatga agtcaagggt ggttatatca tcaaggtcga
      421 tggaaaatat tatgtctacc tgaaagatgc agctcatgct gataatgttc gaactaaaga
      481 tgaaatcaat cgtcaaaaac aagaacatgt caaagataat gagaaggtta actctaatgt
      541 tgctgtagca aggtctcagg gacgatatac gacaaatgat ggttatgtct ttaatccagc
      601 tgatattatc gaagatacgg gtaatgctta tatcgttcct catggaggtc actatcacta
      661 cattcccaaa agcgatttat ctgctagtga attagcagca gctaaagcac atctggctgg
      721 aaaaaatatg caaccgagtc agttaagcta ttcttcaaca gctagtgaca ataacacgca
      781 atctgtagca aaaggatcaa ctagcaagcc agcaaataaa tctgaaaatc tccagagtct
      841 tttgaaggaa ctctatgatt cacctagcgc ccaacgttac agtgaatcag atggcctggt
      901 ctttgaccct gctaagatta tcagtcgtac accaaatgga gttgcgattc cgcatggcga
      961 ccattaccac tttattcctt acagcaagct ttctgcctta gaagaaaaga ttgccagaat
     1021 ggtgcctatc agtggaactg gttctacagt ttctacaaat gcaaaaccta atgaagtagt
     1081 gtctagtcta ggcagtcttt caagcaatcc ttcttcttta acgacaagta aggagctctc
     1141 ttcagcatct gatggttata tttttaatcc aaaagatatc gttgaagaaa cggctacagc
     1201 ttatattgta agacatggtg atcatttcca ttacattcca aaatcaaatc aaattgggca
     1261 accgactctt ccaaacaata gtctagcaac accttctcca tctcttccaa tcaatccagg
     1321 aacttcacat gagaaacatg aagaagatgg atacggattt gatgctaatc gtattatcgc
     1381 tgaagatgaa tcaggttttg tcatgagtca cggagaccac aatcattatt tcttcaagaa
     1441 ggacttgaca gaagagcaaa ttaaggctgc gcaaaaacat ttagaggaag ttaaaactag
     1501 tcataatgga ttagattctt tgtcatctca tgaacaggat tatccaagta atgccaaaga
     1561 aatgaaagat ttagataaaa aaatcgaaga aaaaattgct ggcattatga aacaatatgg
     1621 tgtcaaacgt gaaagtattg tcgtgaataa agaaaaaaat gcgattattt atccgcatgg
     1681 agatcaccat catgcagatc cgattgatga acataaaccg gttggaattg gtcattctca
     1741 cagtaactat gaactgttta aacccgaaga aggagttgct aaaaaagaag ggaataaagt
     1801 ttatactgga gaagaattaa cgaatgttgt taatttgtta aaaaatagta cgtttaataa
     1861 tcaaaacttt actctagcca atggtcaaaa acgcgtttct tttagttttc cgcctgaatt
     1921 ggagaaaaaa ttaggtatca atatgctagt aaaattaata acaccagatg gaaaagtatt
     1981 ggagaaagta tctggtaaag tatttggaga aggagtaggg aatattgcaa actttgaatt
     2041 agatcaacct tatttaccag gacaaacatt taagtatact atcgcttcaa aagattatcc
     2101 agaagtaagt tatgatggta catttacagt tccaacctct ttagcttaca aaatggccag
     2161 tcaaacgatt ttctatcctt tccatgcagg ggatacttat ttaagagtga accctcaatt
     2221 tgcagtgcct aaaggaactg atgctttagt cagagtgttt gatgaatttc atggaaatgc
     2281 ttatttagaa aataactata aagttggtga aatcaaatta ccgattccga aattaaacca
     2341 aggaacaacc agaacggccg gaaataaaat tcctgtaacc ttcatggcaa atgcttattt
     2401 ggacaatcaa tcgacttata ttgtggaagt acctatcttg gaaaaagaaa atcaaactga
     2461 taaaccaagt attctaccac aatttaaaag gaataaagca caagaaaact caaaacttga
     2521 tgaaaaggta gaagaaccaa agactagtga gaaggtagaa aaagaaaaac tttctgaaac
     2581 tgggaatagt actagtaatt caacgttaga agaagttcct acagtggatc ctgtacaaga
     2641 aaaagtagca aaatttgctg aaagttatgg gatgaagcta gaaaatgtct tgtttaatat
     2701 ggacggaaca attgaattat atttaccatc gggagaagtc attaaaaaga atatggcaga
     2761 ttttacagga gaagcacctc aaggaaatgg tgaaaataaa ccatctgaaa atggaaaagt
     2821 atctactgga acagttgaga accaaccaac agaaaataaa ccagcagatt ctttaccaga
     2881 ggcaccaaac gaaaaacctg taaaaccaga aaactcaacg gataatggaa tgttgaatcc
     2941 agaagggaat gtggggagtg accctatgtt agatccagca ttagaggaag ctccagcagt
     3001 agatcctgta caagaaaaat tagaaaaatt tacagctagt tacggattag gcttagatag
     3061 tgttatattc aatatggatg gaacgattga attaagattg ccaagtggag aagtgataaa
     3121 aaagaattta tctgatctca tagcgtaagg aatagcagta gaaaaagtct gaatcaaaaa
     3181 tgaagttctc tcaaaagtta gaaataaaac tctgactttg ggagaatttc attttattat
     3241 taatatataa aatttcttga catacaactt a
//
LOCUS       DAVKBK010000102         3242 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVKBK010000102 DAVKBK010000000
VERSION     DAVKBK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3242
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.102"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(159..413)
                     /locus_tag="VWX69_001956"
     CDS             complement(159..413)
                     /locus_tag="VWX69_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU9193238.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
     gene            complement(433..2274)
                     /gene="typA"
                     /locus_tag="VWX69_001957"
     CDS             complement(433..2274)
                     /gene="typA"
                     /locus_tag="VWX69_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU9193239.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            2436..3161
                     /locus_tag="VWX69_001958"
     CDS             2436..3161
                     /locus_tag="VWX69_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEU9193240.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGKILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
BASE COUNT          960 a          719 c          615 g          948 t
ORIGIN      
        1 gcaaccagta ctaaccaaat ataaaataga ttccattaac gaattttatt caagtttttc
       61 ccattcatat tatccaaaca aaagagatgg tgataactca aaaataaatt gcaatcttgt
      121 aaaattccta gcaaaaaaga gagccaaaac tctctttttt atcttctttt actttttttg
      181 actggcatga gtgtaatgtc tctaacacta aagtaagcta ggagcaacat ggctattgct
      241 aggaatattt ctgttggtaa ttgaaaaatt ttcagaaaag atagaaccaa taaaatcaag
      301 agtgccacta aaatacatac catagcgacg atattgactg tccctttaat gctttctggt
      361 gtcgcaaata catagagtag gagcagtaaa attcctagga ctaaatagac catctttctc
      421 tctttctagc tcttattcag ctgatttttt cttcttgtta gctttctcac gctctgcttt
      481 gttaaggatt tgtttacgca aacggataga ctcaggcgtt acttccatgt actcatcgtc
      541 gttcaagaac tcaagagact cttcaagtgt caagatacga ggcgtcttga taacagctgt
      601 ttggtcctta gtagctgaac gaacgttggt catttgtttt gccttcgtga tgttaactgt
      661 caagtcattt tcacgagagt tttcaccgat gatcattcct tcataaacct cagtacctgg
      721 gttgacaaag atcgtaccac gttcttcgat agacatgatt gagtaagttg tagccttacc
      781 agcatcgata gaaacaaggg caccacggtg acgtccacca atttcccctg gaatcaatgg
      841 caagtattgg tcgaaggtat ggttcatgat accgtaacca cgagtcattg acaagaactc
      901 agttgagtat ccaatcaaac cacgcgctgg aacaaggaag accaaacgag tttgaccatt
      961 accagttgaa atcatatcca acatttcacc tttacgttca gaaaggcttt ggataacaga
     1021 cccttggtat tcttctggag tgtcgatttg tacacgttca aatggttcac atttaacacc
     1081 gtcgatttct tttacgataa cttctggacg agatacttga agttcatagc cctcacgacg
     1141 cattgtttcg ataaggattg acaagtgcaa ttctccacgt cctgaaacag tccatttatc
     1201 tggtgaatca gttgggtcaa cacgaaggga aacgtctgtt tgcaattccg cctgcaagcg
     1261 ttcttccacc ttacgagaag ttacccattt accttcttta ccagcaaatg gtgagttgtt
     1321 gaccaagaaa gtcatttgaa gagttggctc atcgatgtgt aggattggaa gagcttctac
     1381 tgcatctgtc ggagtgatgg tttcaccgac aaagatgtct tccatacctg aaacggcaat
     1441 caagtcaccc gctttggctt cttggatttc acgacgttcc aaaccaaaga aaccgaagag
     1501 ttttgtaaca cggaagtttt tagttgtacc gtcaagttta gaaagggtaa cttggtcccc
     1561 aaccttaact gtaccacgga agacacgacc gataccgata cgtccaacga agtcattgta
     1621 gtccaaaagt gacacttgga actgcaaagg ctcatctgag ttatctactg gagctgggat
     1681 atggtcgata atcgtgtcaa agattggtgc catagtcgct tcttggtcag ctggatcatc
     1741 tgacaatgaa gaagttccgt tgatcgctga agcataaacc actgggaaat caagctggtc
     1801 gtcatctgca ccaagctcga tgaaaagttc caagacttca tccactactt ctgctggacg
     1861 agctgatggc ttatcgattt tgttaacaac cacgattggg acaaggtctt gttccaaggc
     1921 ttttttcaat acgaaacgag tttgtggcat ggttccttca taggcatcta cgaccaagac
     1981 aacaccgtca accattttca tgatacgctc aacttctcca ccgaagtccg cgtgtcctgg
     2041 tgtgtccata atgttgatac gagttccgtt gtaagcaacg gcagtatttt tagcaaggat
     2101 ggtgattcca cgctcttttt cgatatcgtt tgagtccata gcacgctctg ccaattcagt
     2161 acgtgcatca agcgtttctg attgtttcaa taattcgtca accagggttg ttttaccgtg
     2221 gtcaacgtgg gcgataatcg caatgttacg gatatcttct cttaattttg tcatgatttc
     2281 ctctataata ttcaaaattt attttctaac tgaacgatta taccataatt tcaaataaat
     2341 aacataactc aagcaagtgt aaatgttttc actccgcttt tcttttcacg tcaagccttt
     2401 tcaaagcaag cgacttatga taagataggc acagtatgcg tttagataat ttattagccc
     2461 aagaaaaaat cagccgaaag gccatgaagc aagcactcct cagagggaaa attctagtcg
     2521 atggttgccc agcccgctcc ctagctcaaa atatcgatac aggactacaa gaactccttt
     2581 ttcaggatcg aatcattcaa ggctatgaac acacctatct tatgcttcat aaacctgctg
     2641 gtgtcgttac agccaacaaa gacaaggaac ttccgaccgt catggacctg cttccatctg
     2701 acatccagtc tgacaagctc tatgccgttg gccgactgga ccgagataca acgggactcc
     2761 tcctcttgac cgataacggt cccttgggct tccaactcct ccatccccaa tatcatgtcg
     2821 ataagactta tcaagttgag gttaatggac ttctaacacc tgaccatatc caagcctttc
     2881 aaaagggaat tgtcttttta gatggtactg tctgtaaacc cgcaaaacta gagattctat
     2941 ctgcaagtcc ctccatcagt caagcctcta tcaccatttc agaaggaaaa tttcatcaaa
     3001 tcaagaaaat gttcctctcg gttggtgtta aggtgactat cctcaagaga atccaatttg
     3061 gggacttcac attgaaccca gatttagcag aaagtaacta ccgccctttg aaccaaaaag
     3121 agttacaaat cattaaaaac tatttagaga tgagtcgata aaacaaaaaa agctttaaaa
     3181 ctaaagcttt tttcttttat ttaccgaaaa attaaggcga ttgctacaat ccagttaact
     3241 ac
//
LOCUS       DAVKBK010000103         3041 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVKBK010000103 DAVKBK010000000
VERSION     DAVKBK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.103"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(99..632)
                     /locus_tag="VWX69_001959"
     CDS             complement(99..632)
                     /locus_tag="VWX69_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU9193241.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(721..1497)
                     /gene="recX"
                     /locus_tag="VWX69_001960"
     CDS             complement(721..1497)
                     /gene="recX"
                     /locus_tag="VWX69_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU9193242.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1535..2890
                     /gene="rlmD"
                     /locus_tag="VWX69_001961"
     CDS             1535..2890
                     /gene="rlmD"
                     /locus_tag="VWX69_001961"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9193243.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            2952..3023
                     /locus_tag="VWX69_001962"
     tRNA            2952..3023
                     /locus_tag="VWX69_001962"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2985..2987,aa:Glu,seq:ttc)
BASE COUNT          958 a          550 c          571 g          962 t
ORIGIN      
        1 ctctgctata atggatttat tcctttttgt atttacacaa tttattttat actaccaaaa
       61 aaacaaggtc aggattttgt tcctgacctt tgacaacttt accgattctt tagttctaca
      121 tagcgcttgt accaaatgtt tacataggct tctgagaaag gaccacgtcc attgttaatc
      181 caatcaacaa gaattttgac atgttctttt aaaatatagt ccaagtcatc agaataattc
      241 attttgcgtt tgtgacgctc gtattcttca acgtccaaga gacgtttttc cccatctgta
      301 aaaattttaa catccaaatc gtaatcaata tacttcagtg cttcttcatc cagatagtag
      361 gggctagcca tattgcaata gtaagaagtt ccattatcac gaatcatggc aatgatatta
      421 aaccaatatt tcttgtgaaa gtaaacaata gccggttctc gagtgaccca acgacgacca
      481 tcactttcgg taacaagtgt atgatcgttg acaccaataa tggcgttttc tgttgttttt
      541 agtaccatgg tgtcccgcca agttcggtgg agactcccat catgcttata actttgaatt
      601 gtaataaagt cgccttcttt tggaagcttc ataactaacc aactttctac aatttataag
      661 tttatcattt actattgtac cataaaatta cctaaaatct gtgaatttca cttggaaata
      721 ttaaagatat tctctaagag cgcttgctat atccgaaaaa tcgtagccct ttcgtgctaa
      781 aacttgagtt aaacgctgct tcagttcgta tccttcatac tttcgagcat acttagtata
      841 ttgcttatca agttccttga agatgagttc ttgagtcgtt tcttggtcaa cttggctatc
      901 taagtcgtca aaggcaattt tagcatcaga ataagagaag cccttgttag tcaagttctg
      961 gataatctta tcttgcaggg cacgagctgg aagttttccc tcatattttt tcaatagttt
     1021 attggctaca cgttgagcaa cttcagaaaa atcaaattct ttcaagttct cttctatagt
     1081 agattttgaa atcccttttt gagatagttt ctgagtcagc acataaggac ccttgtctcc
     1141 tgaaagttga ttggtattga tgatagcata agcgtactga ccatcattaa tccacttatc
     1201 ttctttaaga ttagcaataa cttgagaaac gatgttttta tcaatatcgt attttttcag
     1261 atattctctg acttcttttt cagtgcgtgc tttaaaggat aagtggtaga gagcgagatt
     1321 cttaccataa gaaaattgag caaagtcttg aatctctttc aattcctctt cgcttatcac
     1381 cttatctctc gataacataa aacgaacaat tgtatcttcg gtgatatagc atttgtcgcc
     1441 attatcaagc tccatcaggt agagtctttt tttcttttca agttttgtga ttttcatagc
     1501 tctattataa ctcaaaatgt gataagatag gggtatgaat ctgaaagtga aacaaaaaat
     1561 accattaaaa atcaagcgca tgggaattaa cggtgaggga atcggctttt accaaaaaac
     1621 attagtcttt gtaccaggag ctctcaaagg cgaagatatc tattgtcaga ttacttctat
     1681 tagacgcaac tttgttgaag caaaattact gaaggtcaac aagaagtcta aatttcgaat
     1741 tgtgccatct tgtactattt ataatgaatg cggaggctgc caaatcatgc acctgcatta
     1801 tgataagcag ctggagttca agacggactt acttcatcaa gcgctgaaaa aatttgctcc
     1861 tgcaggatat gaaaattatg aaattcgtcc aactattgga atgcaggaac caaaatatta
     1921 cagagctaag ttacaatttc agactcgaaa atttaaaaat caggtcaagg cgggcttata
     1981 tgcacaaaac tctcactatt tagtagagtt gaaagactgc ctggtacaag ataaggaaac
     2041 ccaagtgatt gctaatcgct tagcagaatt acttacttat caccagattc caatcacgga
     2101 tgagagaaaa gttctaggtg tccgtactat tatggtccga cgcgcgagaa agaccggaca
     2161 ggttcagatt attattgtta caaaccgcca gcttaattta actcaattgg taaaagagtt
     2221 ggttaaagat ttcccagaag ttgtgacagt agctgttaat acaaatacag ctaaaaccag
     2281 tgagatatat ggtgaaaaga cagagattat ctgggggcaa gagagtattc aagaaggtgt
     2341 actcaattat gaattttcac tatcccctcg agctttttat caactaaatc ctgagcaaac
     2401 agaagtcctc tatagcgaag cagtaaaagc gctggatgtt gataaagaag accatttgat
     2461 tgacgcttat tgtggagttg gaacgattgg atttgccttt gcaaagaaag ttaaaacact
     2521 cagaggtatg gatattattc cagaagctat tgaagatgcc aagcgaaatg ctaaaagaat
     2581 gggatttgac aatactcatt atgaagctgg aacggcagaa gagattattc ctcgttggta
     2641 caaggaaggc taccgagcag atgctttgat tgttgaccca ccacgtacag gtctggatga
     2701 taagttatta gatactattc ttacttatgt accagaaaaa atggtttata tttcttgtaa
     2761 tgtttcgacc ttggctcgtg atttggtacg cttagtagaa gtctatgatc ttcattatat
     2821 ccagtcggtc gatatgttcc cacatacagc tcgaactgaa gctgttgtaa aattaataaa
     2881 aaaagtttaa aaaagtagtt gacaaagttt gaaaaggctg tataatagta agagttgaaa
     2941 ataacaactc aggtccgttg gtcaaggggt taagacaccg ccttttcacg gcggtaacac
     3001 gggttcgaat cccgtacgga ctatggtatg ttgcgtcagg a
//
LOCUS       DAVKBK010000104         2946 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVKBK010000104 DAVKBK010000000
VERSION     DAVKBK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.104"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            1..355
                     /locus_tag="VWX69_001963"
                     /pseudo
     CDS             1..355
                     /locus_tag="VWX69_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            522..722
                     /locus_tag="VWX69_001964"
     CDS             522..722
                     /locus_tag="VWX69_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193244.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            764..1169
                     /locus_tag="VWX69_001965"
                     /pseudo
     CDS             764..1169
                     /locus_tag="VWX69_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1400..2107
                     /gene="ccdA2"
                     /locus_tag="VWX69_001966"
     CDS             1400..2107
                     /gene="ccdA2"
                     /locus_tag="VWX69_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9193245.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2118..2675
                     /gene="sdbB"
                     /locus_tag="VWX69_001967"
     CDS             2118..2675
                     /gene="sdbB"
                     /locus_tag="VWX69_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU9193246.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKIVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
BASE COUNT          943 a          532 c          614 g          857 t
ORIGIN      
        1 gctatgggtt acactcgaaa aaaagaacca cacctactat gaacaagacc cagaaaaagt
       61 agccttattt cttaagaatt ttaatagttt aaagcaccta gcacctgttt agattgacga
      121 aacaggattc gatacttatt tttatcgaga atatggtcgc tcattaaaag gtcagttaat
      181 aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
      241 tggtgaatta atcgctccaa tgacttacga agagatgatg acgagcgact tttttgaagt
      301 atggtttcag aagtttctct taccaacatt aaccacacca tcggttatta tagtaaaatg
      361 aaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      421 gtccatatgt actattctag tttcaatata ccataactgt tcctagtcaa cctgcaagcc
      481 ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca agcgcttcgg
      541 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      601 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatccg aaaatcgatg
      661 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      721 aaggtctgca tactgcagta gagtctgtga aggctgggct gccttggact ctctcaaaga
      781 tgtgaaagca aatgctagcg acagcaagcc tacacaggac aagaaggatg caaaacaagg
      841 aacggaagat agtaaggatt cagataagat gactgaaaca aactcagttc cagcaggagt
      901 gattgtggtc agtctacttg ccctcctagg cgtgattgcc ttctggctaa ttcgccgtaa
      961 gaaagagtca gaaatccagc aattaagcac ggaattgacc aaggttctag gacagctaga
     1021 tgcagaaaaa agcggataaa aaagtccttg ccaaagccca aaaccttctc caagaaaccc
     1081 ttgatttcgt gaaagaagaa aatggctcag cagagacaga aactaaacta gtagaggagc
     1141 ttaaagcaat ccttgacaaa ctcaagtaaa acatgattta tgaaatgtca gacctaaaag
     1201 acattttcgt tcacaaaagc agcgacgagt aatccttgtc gttgcttttt ggctattttg
     1261 ggggataaga tccgccttga ctagcaaaag aaaagattgg tccaatagtg cccgatacga
     1321 ttttgcgtag cagaaagctt acaaataaaa ttgaatatag taaaatagga ttagaattat
     1381 taagaaagtt ggttctttat tggaaacgat agtattttta atctctgttt ttctagcagg
     1441 tgttttatcc tttttttctc cttgtatttt tcctcttctg ccagtctatg ctgggatttt
     1501 attggatgat caagaaagtg caaaaagctt ttctttgttt gggagaaagg ttctctggtc
     1561 aggcttgatt cgaacacttt gctttatcgc tggtatctct ctcattttct ttattctagg
     1621 ctttggtgct ggttactttg gtcatattct ctatgcaaat tggtttcgat atggcatggg
     1681 agctattatt atcattttgg gtcttcacca gatggaaatt tttcatttga agaaattaga
     1741 agttcaaaaa agttttacct ttaaaaaatc agactctaat cgttattggt cagctttttt
     1801 acttggtatt acctttagct ttggttggac accttgtatt ggtccagttt taagttctgt
     1861 tttagcactt gcggcttctg gaggcaatgg cgcttggcaa ggagcgattt atactctcat
     1921 ttacactctg ggcatggccc ttcctttctt ggtattggca ctagcttcag gtctagtcat
     1981 gccatatttt agtaaaatca agcgtcatat gatgctacta aagaaaattg gtggtttcct
     2041 cattgtttta atgggaattt tgttactatt aggacaagta aatgttctag ctggaatttt
     2101 tgaataaagg aggacaaatg aaaaaagtaa tgtttgctgg cttaagtctc ttgtcattag
     2161 ttgtattgat ggcctgtggt gaggaagaaa ctaaaaagac tcaagcagca caacagccaa
     2221 aacaacaaac gactgtacaa caaattgctg ttggaaaaga tgctccaaac ttcacattgc
     2281 aatccatgga tggcaaagaa gttaagttat ctgattttaa gggtaaaaag gtttacttga
     2341 agttttgggc ttcatggtgt ggtccatgca agaaaagtat gccagagttg atggaactag
     2401 cggcgaaacc agatcgtgat ttcgaaattc ttactgtcat tgcaccagga attcaaggtg
     2461 aaaaaattgt tgagcaattc ccacaatggt tccaggaaca aggatataag gatatcccag
     2521 ttctttatga taccaaagca accaccttcc aagcttatca aattcgaagc attcctacag
     2581 aatatttaat tgatagccaa ggaaagattg gaaagattca atttggtgct atcagtaatg
     2641 cggatgcaga agcagcattt aaagaaatga actagaatcg ataaaatctg attacaagat
     2701 gtagtcagat tttggtaact tctaaaacta acttccagtt tcccacaacc tagcttttag
     2761 tatgagaaaa acgcgtgaca tcagtggaaa tccgtcttag actaacttcc actggttttc
     2821 tttttcttga tatataaggg ttcaaaagcg aaaagactca gaaaaagtgc acgacaaata
     2881 gccctaaaac agagtcgtct tagagtaact tccagttttg ggagagagat ggaagttact
     2941 ttgaga
//
LOCUS       DAVKBK010000105         2841 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVKBK010000105 DAVKBK010000000
VERSION     DAVKBK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2841
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.105"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..368)
                     /locus_tag="VWX69_001968"
     CDS             complement(<1..368)
                     /locus_tag="VWX69_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193247.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIK"
     gene            complement(426..1139)
                     /locus_tag="VWX69_001969"
     CDS             complement(426..1139)
                     /locus_tag="VWX69_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU9193248.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1597..1977)
                     /locus_tag="VWX69_001970"
                     /pseudo
     CDS             complement(1597..1977)
                     /locus_tag="VWX69_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(2394..>2841)
                     /locus_tag="VWX69_001971"
     CDS             complement(2394..>2841)
                     /locus_tag="VWX69_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU9193249.1"
                     /translation="RNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDE
                     KENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEK
                     VTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESK"
BASE COUNT          881 a          559 c          439 g          962 t
ORIGIN      
        1 tctttaatat tattaacttt ttgttcgtag gcatattttg ctacatgatc taggtatata
       61 tcaaaaaagt catgaggaaa atctcccata cagccattac gattcatatt gaggctatat
      121 tttcgattag taagataatt cggaaatata tttcctatta ctctaagatt atctacttgt
      181 gaatcccttc tcccaatata atccccttct ttgactaatg atggagattt ccaagtaaaa
      241 attaaatcgc cagagaaatt tttcttatca aaaaacttaa aaagagattg ataaatacta
      301 tttgctaatt gacaagtgtc agatgtaaat tcataattaa cagcttcatt aaaatcaact
      361 tcagacattt caatgtactc ttcaatagta atattagctt ttttgtagtc attagctcgt
      421 ctcctttaaa atgtgatctt ttcaagaata tttttatcta aacaatccag caagtcttgg
      481 taagaataga cttcgtaagt cggctgggct tgtgtgtgat tttcgaggtg atgaggatta
      541 taccagatag tgtcaatccc cgcattattg ccaccttgaa tgtcggcggt tagagaatct
      601 ccaatcatca gcgtcttttc tttactaaat ccagcaattt gctggccaat cttttcataa
      661 aaaagagcat ccggcttttg agtttgcaac tgttctgaga taaagacttg attgaaataa
      721 ggtgctagac cagattgagc caaacgtcct gtctgaatgg cagtaatgcc atttgtcgca
      781 gcatacaagt cataatcacg ctcaatgagg ctgtccaaga gatcatgagc gcccgatagt
      841 gtttgtccct gctgagcgag ataaaattgg taacgctggg caagaaaact accgtctttt
      901 tcctgtccaa aatgagaaaa taaacgagaa aagcgcgtgt taaccagctc ttgtttactg
      961 attttcttca gctccaagtc tttccagaga gccttgttca taggaacgta ataatcttta
     1021 taagcctgaa tatccgcaac tccttcttct tttagaagtt gggtcaaagc cacatcctca
     1081 gcagcatcaa aatcaagaag agtgtggtcg aggtcgaaga gtagaaattt gtagaacaat
     1141 ttgaggtttt cctttctgaa aattcattaa gaacattata tcataaagca cctcatacaa
     1201 ttaactaatt taatcactta aaaaaattcg aacactttct atacaactga cagctcaaat
     1261 ctttcagaat agaacaatac taactatcga gcaccccgta ttcataaata tatgtgtaat
     1321 tctagaccta gaattcctat aaactaaatg ctttcatact cttccaagta attgattgcc
     1381 ttaaatttta atttttgaag gtttctaaag ctagaatagc cccatcacaa tcagttttga
     1441 ttgattcaca atttagaaac actatagttt cactcctgtt aaaataaaaa ggaactgcat
     1501 aaagcaatcc ctttctgatt ttgaaatcat ttacttaaca ttttatagtt gagataatca
     1561 atagcttacc tataaaaaga gttatagtaa aattccttat ttattgattt caagctccgc
     1621 taactgtgtt tgaataactg acagttctgc accagcctga agaagagcag ctgcattata
     1681 ggcaccttct acaattggaa ccctgttgat gatgatactt ttatcactga aatcagtcac
     1741 catttttaag ttcattttag cagaacctag gtcaaaaaag gcaagtaaag tatctgctgt
     1801 attttcggaa acaaccctat ctacttaatc aaaactcgtt ccaattcctc cgccctcggt
     1861 tcctcctaca taagtaatcg gaacatcttt agctacttta ctaatcagtt caacaacacc
     1921 ttctgcaatg tgtttggaat gtgaaacgat aacaagacca ataccaatac tttccatcaa
     1981 accaccccag tttctaaaat agcagtaaag agtaatcctg atgagaatga tccaggatca
     2041 atatgtccaa gaaaccatat gctcctaaga caagagccaa cagactggtc atcaataata
     2101 gtattgttct ttttttcatc attactcctt aactagtgtt taactgatta attagccagt
     2161 aaatagttta tctttattta cactatctgt taagatatag taaaataaga acaggacagt
     2221 caaatcgatt tctaacaatg ttttagaagt agaggtatac tattctagtt tcaatctact
     2281 atattttgca cattttcatg aaaaaaatga gaactagaac tcacattctg ctctcatttt
     2341 tcgttttccc gttctcctat cctgttttta ggagttagaa aatgctgcta cctttactta
     2401 ctctccttta ataaagccaa gagactatct acttctgctg aaatagtgtt attatctttc
     2461 gttccgagaa gaagactact ttttagacca gtcaatgtct ccacagcatt ttgtctaata
     2521 ctagaatctg ttactttttc tagcaaggcc tccgcatctg ctatcttagc gttaataaca
     2581 gaatgctcta cttgaggaat ttcagcctca tctgtagtat cttcagcttc ttcctctgtc
     2641 tcttccgtat cagtgcttgg tttataaaga ttatctgctg aaggatttaa accagcgtga
     2701 ttctcttttt catcagattc agggtgagtt ggctcactta cttcatcatg ttccttatct
     2761 tcctcaggtt tttctgtctg aggtttctcc tcgtttggtt tttccgtttg attggtatca
     2821 gcttgaccat ttttgtttct t
//
LOCUS       DAVKBK010000106         2745 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVKBK010000106 DAVKBK010000000
VERSION     DAVKBK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.106"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..773)
                     /locus_tag="VWX69_001972"
     CDS             complement(<1..773)
                     /locus_tag="VWX69_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9193250.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAYG
                     GNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWI"
     gene            complement(807..1772)
                     /locus_tag="VWX69_001973"
     CDS             complement(807..1772)
                     /locus_tag="VWX69_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9193251.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1890..2303)
                     /locus_tag="VWX69_001974"
     CDS             complement(1890..2303)
                     /locus_tag="VWX69_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU9193252.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(2300..2536)
                     /locus_tag="VWX69_001975"
     CDS             complement(2300..2536)
                     /locus_tag="VWX69_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU9193253.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            complement(2596..>2745)
                     /locus_tag="VWX69_001976"
     CDS             complement(2596..>2745)
                     /locus_tag="VWX69_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HEU9193254.1"
                     /translation="KILLPLPPLALQNEFADFVVQVDKSQLAIQKSLEELETLKKSLM
                     QEYFG"
BASE COUNT          812 a          546 c          402 g          985 t
ORIGIN      
        1 cttatccata ccttaccgtg ggtagttctt acattaccac aatatgcacc tacacgacca
       61 atgatgatag taggattatc aattaaatat tttcgacttt tccaagcaat gccatttcca
      121 ccataggcag gataaccttc aaaaactcta tcatgtttat caagaaattt tccacttgaa
      181 aatttaaaac actgttgtcc cgtttttact gcaaatttct tgttattatt taaaggatcc
      241 ccaaacatct cgttaaatcg ggattttaca agtagattaa gctcttcaag ttgttcttgt
      301 ctccttaaaa tcagcttgct taacaaatcc agctcacttg caattctttg ttgctctccc
      361 aaatttgtat atggaactat aatattatca aaatattttt tagttaaatg tttcattgtg
      421 gaaccatgag tatgttttac agcatcttgt aaaccttttt caacaacata tttaaaatac
      481 gatttatcta tatctatctt atcaaaaacc actttaaaaa tgtgctgatt taatactgcg
      541 gatcttccac accactgaaa aacccctaat gtacccgacc acgaaataag aatatcacca
      601 gcttcaacaa tgtatttttt atcaatcgta cccgaataat aatttatccc ttttgaagtt
      661 ttagtcagat tctgtattct gataatctct ttcccttcag atgaccaatc ttgaggttta
      721 aaagcatagc cattgataaa agtagccact tgccctaatt tcactttctt catgcaacca
      781 cctcctcgga atatcgggat ttgcttttaa gagatgaatt tttggtgtga atgcttgaca
      841 ttattttgat tgaccatggc ataggccagg gttgtgtcaa tcttgctatg acctagcagt
      901 ttttggactt gttcgatagg cataccttta tcaattgcct tagtcgctaa agttcttctg
      961 aacttatgtg ggtgaacctt ttgtatgccg agtttgtctc ctaactttct taagcgaatc
     1021 tctacaccag caattccaag tctctgggct tttccaacta gcgttacaaa aagagcaggg
     1081 tgactatctt ttctgtcgtt aagataattt cttaaatgaa ttttcgtccg agcgtcaaaa
     1141 tatactggtc tctccttctt tcctttacca aagacaacac actctctgtt ttcaaaatca
     1201 atatctgaac gattcaactg tacaagctcc cctacacgca tacctgtcga tgctagtagg
     1261 tctattattg ccaaatctct caaattttca cagttatcac gcataatttc caaatgttca
     1321 tcagtataag tttccttcac attttgctca gtcttaattt tctttatccg tcgaatggga
     1381 tttttaatga tatattcctc ttgctcaagc caagcaaaaa aagaagacaa tatacgccta
     1441 atattgtcta aatttgcctt actacaatcc ttttcagact ggtaatttgc taaataactc
     1501 cttaaatcat ctgttgtgag ttgtgtcaca gactctttaa tagcattaaa caagttttca
     1561 atcgtcctct ggtaataacg aattgttttt gagctacagc cctctacctg cttggcggta
     1621 ataaatagtt gcaacaggtt attattcgaa tacttctgct gcttttttcc gtctactaga
     1681 tgatgttcta aactctctct caacgctagt aattgttcat tatttaaaag aggtaacatt
     1741 tcttgcatga taattgtaac ttttgattcc ataatttctc actttcttat tcatcaataa
     1801 aaagagacaa tatcagtttc tgcattacag aattctaata ttgtctgttc atttattttc
     1861 ttgtgctcat tcaaatccag catactaggt tactttttga ccttttctct aacagaatgt
     1921 tcagaaaccc atttggagta gcttgtcatt ttttcatcag ttaaagcttc tactgcgatg
     1981 gttacacaca tttttactgc ttcttctacc gttacagaaa aacgatagcc gtttaattgt
     2041 aaaaatttga ccaaaacgaa gaaagcagtt cttttattag cattagcaaa aacatgcttc
     2101 tttatcaatt ggacaaatag tatcgttgct ttatcaaaaa ttgttggata aagagacttc
     2161 ccaaagacaa attgttctgg taagttcaca atcatattta aggcagaaga actaactgtt
     2221 tgaattttct catttggaga ataccgttga attgctaaag catttatttt ttcaatttgc
     2281 ttttctgtca gatagattgt catttttcca ccaaagcttt gaaaacatcg tcgtattcgt
     2341 caaatatttt atctaaattt aagtcaaagg catcatcaga tacataagaa acctgctgcc
     2401 ccaattcttc aggagtaaag ataatctcac cacttggtaa caatttcgct tcgtatttaa
     2461 caccacttgg aatattaaat tcacttggaa tcgtaatggt gattgaattt ccttgttttc
     2521 ttgtttttac taccatctga tttcctcctt tgaagtatta taacaaatca ttaccgtaat
     2581 tacaatggca gaatatcagc caaaatactc ctgcatcaga gatttcttca aagtttcaag
     2641 ttcttccaga gatttttgga ttgccaattg tgatttgtcg acctggacta caaagtctgc
     2701 gaactcattt tggagggcta gtggggggag ggggagaagt atttt
//
LOCUS       DAVKBK010000107         2512 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVKBK010000107 DAVKBK010000000
VERSION     DAVKBK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.107"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..1088
                     /locus_tag="VWX69_001977"
     CDS             <1..1088
                     /locus_tag="VWX69_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU9193255.1"
                     /translation="SFFTVGSMATLFALLSTLVKLFVTFDYIPKVLLQHKVTLIDILV
                     VLFLFFQAFAAFQSQTLYLNYVGGQFFLLGLYSFLKHFLLLDCKTTIKSLFLTFILFL
                     CVQVITQLLFPVGFDSLHPTGDNRLYFLGRKNIATPYIIVGLGGFYLLNKKMNEFISL
                     KEIIFLGLFGILSFLTQSSTAIICYGLFIFIRLLGLKENIGKLYSLVSMAVYVCFSLS
                     IIFSQSTILSTFTAIFSKNATFSGRINIWQLAIRIFEENFWFGRGLNVNFNAWTNGII
                     VNSAHNTLLDILARTGIFPGVLFIVLLMNLFLGKYRIESKTLLAMLASFMIYITMETS
                     SMSILLLIIVLCVYWPRGEEKLHEQVT"
     gene            1072..1941
                     /locus_tag="VWX69_001978"
     CDS             1072..1941
                     /locus_tag="VWX69_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEU9193256.1"
                     /translation="MSKLLNTIYYRLFRLYKKIYLQVFSKKTVDILGEKANLENELIV
                     SFTTIPSRLNYLPSMIKSIFNQTIIPNRFIMYVYKDEFEGINLESILELEIKNGLEIV
                     YVDENLRSHKKYFYAMKDNPNSIVVLVDDDIIYPRNTIKKLIASYRIYPQCVSAMRCH
                     RIKLFSDGSLYPYNQWEYEISGATIPSYFNFFTSGGGTLFPPCTRNEDLFNKKNIREL
                     SFLADDVWLNFLVVKNGIKTVKATRYKGTPLTIDDNPEESLVYLNTVYDNNNDKCIRN
                     MVEYYQINFTEDK"
     gene            1941..>2512
                     /locus_tag="VWX69_001979"
     CDS             1941..>2512
                     /locus_tag="VWX69_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEU9193257.1"
                     /translation="MNVEKNLKRGIFYTAIGKYSNVVIQLLVTAILSRILSPVEYGIV
                     AVVNVFLLFFQMLADSGIGPAIVQNKELNKSDLISIFSLTIYSGIVLSCIFALLGYPM
                     GVLYGETIYVSLFPLLGLCVLFYTITIVPQAILMKTMNFKIVNFLTIFSNIASGLVGV
                     ILAVSHFGVYSLIFSNIVKAMVLFIALYSKA"
BASE COUNT          784 a          339 c          419 g          970 t
ORIGIN      
        1 ctagtttttt tacagttgga tcaatggcga ctttatttgc tttgctttct actttagtta
       61 agctatttgt aacttttgat tatattccca aagttctttt acagcataaa gtaacactga
      121 ttgatattct agttgttcta tttttatttt ttcaagcatt tgcagctttt caaagccaaa
      181 cgttgtacct taactatgtt ggaggtcagt ttttcctttt aggactatat tcatttttga
      241 aacacttttt attgttggat tgtaaaacaa caataaaaag cctcttttta acctttatct
      301 tgtttttgtg tgttcaagta ataactcaat tgctttttcc ggtcggtttc gattctttgc
      361 accctacagg agataataga ctttactttt taggaagaaa gaacatagct accccgtata
      421 tcattgttgg attaggtggt ttttacttat taaataaaaa aatgaatgag tttatatcac
      481 taaaggagat tattttttta ggattgttcg gaattttatc atttttaaca caatccagta
      541 cagcgattat atgttatggg ctttttattt tcatacgtct attgggatta aaggaaaata
      601 taggaaaact atattcttta gtcagtatgg ctgtatatgt ttgtttttct ctttctataa
      661 tcttttcaca aagtacaatt ttatcaactt ttacagcgat tttttccaaa aatgcaactt
      721 tttcaggacg tatcaatatt tggcaattag cgattcgtat ttttgaagag aatttttggt
      781 ttggacgagg cctcaacgtt aattttaatg cttggacaaa tgggattatc gttaattcag
      841 cacacaatac cttattagat atacttgctc gaactggtat atttccaggt gttttattta
      901 tagtgcttct tatgaatctg tttcttggaa aatatagaat agaatcaaaa acactgttgg
      961 ctatgttagc ctcatttatg atttatatta caatggagac ttcatctatg agcatattgc
     1021 tgctaattat tgttctttgt gtatattggc cacgtggaga ggagaagttg catgagcaag
     1081 ttacttaata ccatctatta tcgactattt agattatata aaaaaattta tctacaagtt
     1141 tttagtaaaa aaacggttga catcttgggt gaaaaggcta atttagaaaa tgaactaatt
     1201 gtttcgttta caacaattcc aagtcgtctt aattatttac caagtatgat taaaagtatt
     1261 ttcaatcaga caattatccc taaccgtttt attatgtatg tttataaaga tgaatttgaa
     1321 ggcattaatt tggagagtat tctagaactt gaaatcaaaa atggtttgga aattgtctat
     1381 gtggatgaga atcttcgttc acacaaaaaa tatttttatg ctatgaagga taatccgaac
     1441 agtatagttg ttctagttga tgacgatatc atttatcctc gaaatactat aaagaaactg
     1501 attgcatcct atagaattta tccacagtgt gtttcagcaa tgcgatgtca tcgaattaag
     1561 ttgttttctg atggaagttt atatccatat aatcaatggg aatatgaaat atcaggagct
     1621 actataccat cgtattttaa tttttttact agcggaggtg ggacattatt tcctccatgt
     1681 actcgcaatg aggatctttt taataaaaaa aatatcaggg aactcagttt tctagctgat
     1741 gatgtatggt tgaatttttt ggtagtcaaa aatggaatta aaacagtaaa agcaacacga
     1801 tataaaggga caccattaac tatagatgac aatcctgagg agagtttggt atatttgaat
     1861 accgtatatg ataacaacaa tgataaatgt attagaaata tggttgaata ttatcaaatt
     1921 aattttacag aggataaata atgaatgttg aaaaaaattt gaaacgtgga attttctata
     1981 ctgcaatagg gaagtattcg aatgtagtta ttcaattact tgtaacagca attcttagcc
     2041 ggattctctc acctgtagaa tatggtatcg tagcagtagt aaatgtattt cttttatttt
     2101 ttcaaatgtt agcagattca ggaataggac ctgctattgt tcaaaataaa gaactgaata
     2161 agtcagattt aatcagcatt ttctcattaa cgatttatag tggaatcgta ctttcttgta
     2221 tttttgcttt actaggatat cctatggggg tgttatacgg cgaaactatt tatgttagtt
     2281 tatttccgct tttaggtctt tgtgttttat tttataccat tacaattgta ccgcaagcta
     2341 ttctaatgaa aacgatgaac tttaaaatag ttaattttct aactattttt tctaacattg
     2401 ctagtggctt ggtgggcgtt attctagcgg tatcacattt tggtgtctat tctctaattt
     2461 tttctaatat tgtaaaagca atggttttat ttatcgcttt atattctaaa gc
//
LOCUS       DAVKBK010000108         2297 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVKBK010000108 DAVKBK010000000
VERSION     DAVKBK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.108"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            129..1622
                     /locus_tag="VWX69_001980"
     CDS             129..1622
                     /locus_tag="VWX69_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9193258.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..>2297
                     /locus_tag="VWX69_001981"
     CDS             1635..>2297
                     /locus_tag="VWX69_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9193259.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKN"
BASE COUNT          813 a          335 c          457 g          692 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaggtcatc ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attagaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta aaaaaaggca
     1681 agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt caaatagatg
     1741 atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact gaagcactcc
     1801 cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt tatggattat
     1861 cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac aaagaaaaaa
     1921 ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta cgagaacatt
     1981 caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta caattagaat
     2041 tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt aaagggctta
     2101 ttactaaaag aaaattgcag ttagatgaac taaacttgct cgtcaaatcc cgatttaacg
     2161 agatgtttgg ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg
     2221 gtgatagggg caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat
     2281 ttttaaatac aaagaat
//
LOCUS       DAVKBK010000109         2208 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVKBK010000109 DAVKBK010000000
VERSION     DAVKBK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.109"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            144..1340
                     /gene="tuf"
                     /locus_tag="VWX69_001982"
     CDS             144..1340
                     /gene="tuf"
                     /locus_tag="VWX69_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9193260.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(1449..2208)
                     /locus_tag="VWX69_001983"
                     /pseudo
     CDS             complement(1449..2208)
                     /locus_tag="VWX69_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          677 a          437 c          464 g          630 t
ORIGIN      
        1 ttaaattttt accaagaata attcacaaaa acgttgtaaa acacttgcaa tttagctgaa
       61 atttgataaa atagtaagga aagttagact gtattgccta ctgtctatct ataaaatata
      121 ttttattgga ggcttttact caaatggcaa aagaaaaata cgatcgtagt aaaccacatg
      181 ttaacattgg tactatcgga cacgttgacc acggtaaaac taccctaact gcagctatca
      241 caactgtttt ggcacgtcgc ttgccttcat cagttaacca acctaaagac tatgcgtcta
      301 tcgatgctgc tccagaagaa cgcgaacgcg gtatcactat caacactgcg cacgttgagt
      361 acgaaactga aaaacgtcac tacgctcaca tcgacgctcc aggacacgcg gactacgtta
      421 aaaacatgat cactggtgct gctcaaatgg acggagctat ccttgtagta gcttcaactg
      481 acggaccaat gccacaaact cgtgagcaca tccttctttc acgtcaggtt ggtgttaaac
      541 accttatcgt cttcatgaac aaagttgact tggttgacga cgaagaattg cttgaattgg
      601 ttgaaatgga aatccgtgac ctattgtcag aatacgactt cccaggtgac gatcttccag
      661 ttatccaagg ttcagcactt aaagctcttg aaggtgactc taaatacgaa gacatcgtta
      721 tggaattgat gaacacagtt gatgagtata tcccagaacc agaacgtgac actgacaaac
      781 cattgcttct tccagtcgag gacgtattct caatcactgg acgtggtaca gttgcttcag
      841 gacgtatcga ccgtggtatc gttaaagtca acgacgaaat cgaaatcgtt ggtatcaaag
      901 aagaaactca aaaagcagtt gttactggtg ttgaaatgtt ccgtaaacaa cttgacgaag
      961 gtcttgctgg agataacgta ggtgtccttc ttcgtggtgt tcaacgtgat gaaatcgaac
     1021 gtggacaagt tatcgctaaa ccaggttcaa tcaacccaca cactaaattc aaaggtgaag
     1081 tctacatcct tactaaagaa gaaggtggac gtcacactcc attcttcaac aactaccgtc
     1141 cacaattcta cttccgtact actgacgtta caggttcaat cgaacttcca gcaggtactg
     1201 aaatggtaat gcctggtgat aacgtgacaa tcgacgttga gttgattcat ccaatcgccg
     1261 tagaacaagg tactacattc tctatccgtg agggtggacg tactgttggt tcaggtatgg
     1321 ttacagaaat cgaagcttaa ttcgatttag ttcccagaag aacaattatt taagtcagac
     1381 actaaaagaa tcttgcttgg caaggttctt ttttggttct ttgtcaactg tagtgggttg
     1441 aaaaaaaact aagctcgaga aaggacaaat ttcgtccttt ctttttgatg ttcagggcga
     1501 tgaaaatccg ttttttgaag ttttcaaagt tccgaaaacc aaaggcattg cgcttgataa
     1561 gtttgatgag attattggtc gcttccaatt tggcgtttga atagggtagt tgaagggcgt
     1621 tgacgatttt ctctttgtcc tttagaaagg ttttaaagac agtctgaaaa agaggatgaa
     1681 cctgcttaag attgtcctca atgagtccga aaaatttctc cggttcctta ttctgaaagt
     1741 gaaacagcaa gagttgatag agctgatagt ggtgtttcaa gtcttccgaa taactcaaaa
     1801 gcttgtttaa aatctcttta ttggttaagt gcatacgaaa agtaggacga taaaatcgct
     1861 tatcactcag tttacgacta tcctgttgta tgagcttcca gtagcgcttg atagccttgt
     1921 attcatgaga ctttcgatga aactgattca tgatttggac acgcacacga ctcatagtac
     1981 ggctaagatg ttgtacaatg tgaaagcgat caagaacgat tttagcattc gggagtgaaa
     2041 cagtctggga gactgtttca gcctgagcct agaaatttga aagcgaagct gtttagctaa
     2101 gtcatagtaa ggactaaaca tatccatagt aataattttg acgcgacatc ggacggctct
     2161 atcatattta agaaagtgat ctcggatgac agcttgtgtt ctaccctc
//
LOCUS       DAVKBK010000110         2200 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVKBK010000110 DAVKBK010000000
VERSION     DAVKBK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2200
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.110"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>2200
                     /locus_tag="VWX69_001984"
     CDS             <1..>2200
                     /locus_tag="VWX69_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU9193261.1"
                     /translation="KVEAPKEYTGVQAGAIVEPEKVEPSKEYTGVQAGAIVEPEQIAP
                     LPEYTGVQAGAIVEPEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKSSAL
                     INMNFITDSSKVTGVGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYEWVT
                     PDGQKGTFTANNIHFYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLNDKL
                     NVHGYPARKYTHLKDATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGVHQN
                     GAQNRSGGLILSPTQLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKKLEL
                     RNISSVELYSKDGNKYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTSITNDTKDN
                     RDVYKIVASANSLIQHENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAMNSNPNGTF
                     RLGATMDAREVELPDGQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGELNGATVEK
                     LSLKDVNISAKDDTATLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVNNSTISNSS
                     YTGRITNTYKTVASYQIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQSIGGIVGAV
                     ENSALISNSYAEGNLNNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSDVNVTNGNA
                     IAGYNFNSIKANGTYSNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQI"
BASE COUNT          857 a          303 c          442 g          598 t
ORIGIN      
        1 agaaggtaga agcaccgaag gaatacacag gagtgcaagc cggagcaata gtagaaccag
       61 aaaaagtaga accatcaaaa gaatacacag gggtgcaggc tggcgctatt gttgaaccag
      121 agcagatagc accactacca gaatacacag gggtgcaagc cggagcgata gtcgagccag
      181 agaaagtaga agcactgaaa gaatatactg gtaaaatcga acaacctagt gcagaagata
      241 ctaaaccaaa taatgaaaat actaatacac cagaagaaat gagtattcag aaaaaatcta
      301 gtgcattaat taatatgaac tttattacag attcgtcgaa ggttactgga gtaggatcag
      361 ctacttttat tgcaccaaat gtacttttaa cagtagcaca taatttcatt aataattcta
      421 ctgataatac tactggcgaa tttagaggtg ataaatctaa aaacgtatat gagtgggtga
      481 ctcctgatgg acaaaaagga acatttactg ctaacaatat tcatttttat aataaaaaag
      541 attatccaaa aggatttatc tatgatttag cagtgattaa gctacctgaa acaactggca
      601 gagaacatgt agaattagtt aaaaattatt cgaaagtaaa tcttaatgac aaactaaatg
      661 ttcatggata tccagctagg aaatatacgc acttaaaaga tgctacggta gaaatggaac
      721 aagaatatgc gaataacacc tacggtgttc aatatcaagg tggaaatcct ggtatgagtg
      781 gtggaggaat atttaatgct aatggtgaag ttattggtgt gcatcaaaat ggagcacaaa
      841 atcgctcagg cggattgatt ttatctccta cacaattagc ttggattaag agtattatag
      901 caggtaatga aattccacca gtatacgatg aactttatcg tcataaagat gagaaaaaag
      961 atgacgctaa agatgaaaaa gaagttatta agaaattaga acttagaaat atatcttctg
     1021 tagaactata ttcaaaagat ggtaataagt atcgacatgt aacttcactt gcttctttac
     1081 caagtaatgc agaaaattac tttatgaaag ttaaatcaga gaactttaaa gatgtgatgc
     1141 taccagttac aagcattact aatgatacta aagataatag agatgtttat aagatagtag
     1201 caagtgcaaa tagtctgata caacatgaaa ataataatgt actagaaaat tatacatact
     1261 atttaccaaa aactcagcaa agtgaaactg gggtatatac atcatttaaa aatttagtag
     1321 atgcaatgaa tagcaatcct aatggcacat tccgtttagg agcaactatg gatgctcgtg
     1381 aagttgaact tccagatggt caagaaagtt atgtgaataa tgtattccat ggaatattag
     1441 taggaacaaa taatgagaaa tattatgcta tttataattt gaaaaaacca ttatttgggg
     1501 aattaaatgg tgctacagta gaaaaacttt cactaaaaga tgttaatatt tccgcaaagg
     1561 acgatactgc aacacttgcg aaagaagcaa ataacaatac tcatattgat aacgttcatg
     1621 ctgatggagc gatagctggg gaacgtagca taggaggatt agtatcacaa gttaataatt
     1681 ctactatttc taacagtagc tatacaggta gaataactaa tacatataaa acagttgcta
     1741 gttatcaaat cggaggttta gtaggcaaac tttctggtcc gaggggatta atagataagt
     1801 cgttcgcatc aatcgattta tcttcaaatg caacacaagg agaccagtct attggtggaa
     1861 tagttggtgc agtagaaaat agtgcgctta ttagtaatag ttatgctgaa ggaaatctaa
     1921 ataatgttca acgttttgca aacgttggtg gagtagttgg taatctttgg gatccggttg
     1981 gaggattaga aaaatccggt cgactttcta atgtactaag cgatgttaat gtaacgaatg
     2041 gtaatgctat tgcaggttat aattttaata gtataaaagc aaatggcaca tacagtaata
     2101 aaaataataa ggttgtgaac gtagtacaag aagatgatga aatcttaact aaggattcta
     2161 ctgttcaaag aggagaagta ttagaagatg cacaaataaa
//
LOCUS       DAVKBK010000111         2144 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVKBK010000111 DAVKBK010000000
VERSION     DAVKBK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2144
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.111"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            54..1079
                     /locus_tag="VWX69_001985"
     CDS             54..1079
                     /locus_tag="VWX69_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9193262.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1069..2076
                     /locus_tag="VWX69_001986"
     CDS             1069..2076
                     /locus_tag="VWX69_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9193263.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
BASE COUNT          762 a          302 c          375 g          705 t
ORIGIN      
        1 caatgataat tattatcgat acaatagact tgaaatatgt ttaaggagtt tttatgaaaa
       61 acaaattttt tctaatagct attttagcta tgtgtatagt ttttagcgct tgttcttcta
      121 attctgttaa aaatgaagaa aatacttcta aagagcatgc gcctgataaa atagttttag
      181 atcatgcttt cggtcaaact atattagata aaaaacctga aagagttgca actattgctt
      241 ggggaaatca tgatgtagca ttagctttag gaatagttcc tgttggattt tcaaaagcaa
      301 attacggtgt aagtgctgat aaaggagttt taccatggac agaagaaaaa atcaaagaac
      361 taaatggtaa agctaaccta tttgacgatt tggatggact taactttgaa gcaatatcaa
      421 attctaaacc agatgttatc ttagcaggtt attctggtat aactaaagaa gattatgaca
      481 ctctatcaaa aattgctcct gtagcagcat acaaatctaa accttggcaa actttatgga
      541 gagatatgat taaaattgat tcaaaagcct taggtatgga aaaagaaggt gatgagttaa
      601 tcaaaaatac tgaagctcgt atatccaaag aattagaaaa acatccagaa atcaaaggaa
      661 aaatcaaagg aaaaaaagta ttatttacta tgattaatgc tgcagataca tcaaaattct
      721 ggatttatac tagcaaagat ccaagagcaa attatttaac agatttaggt ctagttttcc
      781 ctgaatcatt aaaagaattt gagagtgaag atagttttgc aaaggaaatt tctgcagaag
      841 aagcaaataa gataaatgat gctgatgtaa tcataactta tggtgatgat aaaactcttg
      901 aagctttaca aaaagatcct cttttaggta aaataaatgc aattaaaaat ggtgccgttg
      961 ctgtaattcc agataataca ccgttagcag cctcatgcac tccaacacca ctttcaataa
     1021 actatactat tgaagaatac ctaaatcttt taggaaatgc atgcaaaaat gcgaaataaa
     1081 aaacaaataa acctaggcat aatttttgta atctgcctag gtcttcttat tacaatattt
     1141 ttgtcattaa agcttggaac aaaagaaatt aatatcagag attttttagc agcttttgga
     1201 atgggcaata caaatgatga ttttattaaa tcaattatat ataaaagaat acctagaact
     1261 atttttgcaa ttttagcagg ttctagtctt gccataagcg gtgtattgat gcaatcagtt
     1321 actagaaacc caatagctga tccaggtata ctcggtataa acacaggagc aagtcttagt
     1381 gtagtaattg gtctttcttt tttaggaatt tcatcaagca taagccatat aagttttgca
     1441 atcattggtg gcttagtaag tgcaattttt gtatacgcga ttgctgtaag cggaaaagca
     1501 ggccttaccc ctataaaact tgccttatca ggaacttgtg ttagtatggc tttaagcagt
     1561 tttgtaagtt ttttaatttt accgaataat aacgtcttag acaaatttag attttggcaa
     1621 ataggtagcc ttggagcagc tacattatct tctatatcta cactactacc ttttataatt
     1681 ttaggtcact tgatagctat atttatttca tcagatttaa acgctttagc tatgggtgat
     1741 gaaatggctg ttggtcttgg agttaatgtt aataggataa gatcacttgc aataattgca
     1801 agtgtgcttt tatgttcaag tattactgca attggtggac ctattggctt cgtaggtctt
     1861 atagttcctc acttttgtgg cttatttata agcaaagata tacgcacaat gaccatttct
     1921 tcatctttta taggtgcaga gctcttgctt atatgtgata taatcggccg tatgttaggt
     1981 aaaccaggtg aaattgaagt agggataatt actgcaataa tcgggggtcc agtacttatt
     2041 tatgtaacta tgaaaaatag aggggttaat aactaatgca aaatttaatt ataggtattc
     2101 aaaaaagaaa aaatagaata acactatttt cctcactatt ttta
//
LOCUS       DAVKBK010000112         2126 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVKBK010000112 DAVKBK010000000
VERSION     DAVKBK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.112"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..772
                     /locus_tag="VWX69_001987"
     CDS             <1..772
                     /locus_tag="VWX69_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9193264.1"
                     /translation="VFNTKSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGIN
                     VTIKKGETVAIVGESGSGKSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGA
                     VLQNSTLSYGTLRENLTFGHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNF
                     SGGQQQMILLARCLLSKPSVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDT
                     IKSADKILVMHNGEIVEIGTHRELLELGGIYKQLYSNN"
     gene            796..>2126
                     /locus_tag="VWX69_001988"
     CDS             796..>2126
                     /locus_tag="VWX69_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU9193265.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIA"
BASE COUNT          799 a          255 c          399 g          673 t
ORIGIN      
        1 tgtgtttaat actaaatccg aattaattcc agaaagagtc agtcaagata taaaatttga
       61 taaaaaaata gaattaaaag atatttggta taaatatgga ttatttgatg attatgtttt
      121 gaaaggaata aatgttacta ttaaaaaagg agaaactgtt gctattgttg gagaatcagg
      181 ttcaggtaag agtacattag ctaaaatttt attaggttta ttagaaccta atattggttc
      241 aatagaagtt gatggagtag aaaaagaaga aattggtcaa acattgtata gaaagatttt
      301 tggagcagtg ttacaaaatt caaccctaag ttatggtacc ttaagagaga atttgacatt
      361 tggacacttt gtttcagatg aagaattaat gacaaatcta aattcaattg gtcttagcaa
      421 tgtagttaaa tctttacctc ttggattaga gacaatcatc gctgaagaag gtaataactt
      481 ttctggaggg cagcagcaaa tgatactttt agctcgttgt cttttgtcga aaccttcggt
      541 agttgttttg gacgaagcaa caagtagttt agataattta tctcaacaaa ttacaacttc
      601 ttacttaagt gaaatcggta ccactaagat tttaattgcc catcgactag atactatcaa
      661 gtctgcagat aagatcttag taatgcataa tggtgaaatt gtagagattg ggacccatag
      721 agaacttctt gaactaggag gcatttataa gcaattgtat tcaaataatt agtttttgat
      781 taaaagggta aatttatgaa gattatgaaa aaaaaatatt ggactttagc gatattattc
      841 ttttgtttgt tcaataattc tgttactgct caagaaatac ctaaaaatct tgatggcaat
      901 ataactcaca ctcagactag cgaaagtttt tctgaatctg atgaaaaaca ggttgactat
      961 tctaataaaa atcaagaaga agtagaccaa aataaatttc gtattcaaat cgataagaca
     1021 gaattatttg taacaacaga taaacattta gaaaaaaact gttgtaaatt ggaacttgaa
     1081 ccacaaataa ataacgatat tgttaactct gaaagtaata atttactagg cgaagataat
     1141 ttagataata aaattaagga aaatgtttct catctagata atagaggagg aaatatagag
     1201 catgacaaag ataacttaga atcgtcgatt gtaagaaaat atgaatggga tatagataaa
     1261 gttactggtg gaggcgaaag ttataaatta tattctaaaa gtaattctaa agtttcaatt
     1321 gctattttag attcaggagt cgatttacaa aatactggat tactgaaaaa tctttcaaat
     1381 cactcaaaaa actatgtccc caataaagga tatttaggaa aagaggaggg agaggaagga
     1441 ataatatcag atattcaaga tagattaggt catggtacgg ctgttgtagc tcaaattgta
     1501 ggggatgaca atattaatgg agtaaatcct cacgttaata ttaacgtcta tagaatattt
     1561 ggtaagtcgt cagctagtcc agattggatt gtaaaagcaa tttttgatgc tgtagatgat
     1621 ggcaatgata ttatcaatct tagtactgga caatatttaa tgattgatgg agaatatgag
     1681 gacggaacaa atgattttga aacatttttg aagtataaaa aggctattga ttacgcgaat
     1741 caaaaaggag taattatagt agctgcatta gggaatgact ccctaaatgt atcaaatcag
     1801 tcagatttat tgaaacttat tagttcacgc aaaaaagtaa gaaaaccagg attagtagtt
     1861 gatgttccaa gttatttctc atctacaatt tcggtcggag gcatagatcg cttaggtaat
     1921 ttatcagatt ttagcaataa aggggattct gatgcaatat atgcgcctgc aggctcaaca
     1981 ttatctcttt cagaattagg acttaataac tttattaatg cagaaaaata taaagaagat
     2041 tggatttttt cggcaacact aggaggatat acgtatcttt atggaaactc atttgctgct
     2101 cctaaagttt ctggtgcgat tgcaat
//
LOCUS       DAVKBK010000113         2096 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVKBK010000113 DAVKBK010000000
VERSION     DAVKBK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.113"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            50..1060
                     /locus_tag="VWX69_001989"
     CDS             50..1060
                     /locus_tag="VWX69_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin formation protein"
                     /protein_id="HEU9193266.1"
                     /translation="MVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLFM
                     YYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTLA
                     CLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSLG
                     DTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPREKIKIH
                     SLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTSMELES
                     LLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLL
                     EI"
     gene            1410..>2096
                     /locus_tag="VWX69_001990"
     CDS             1410..>2096
                     /locus_tag="VWX69_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEU9193267.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYY"
BASE COUNT          759 a          246 c          382 g          709 t
ORIGIN      
        1 aagtttagtt actattctgc ataatgaagt agaaaatatt gcagactctt tggttattaa
       61 taatatttat gacgaatatc caatttggag tatacctgtt aattttaaag gttctaaatg
      121 gtgtcttgaa caaacgggta atgatatgta taggggtaga gctggaatat tactgtttat
      181 gtactatgta aaattattga aagataaatc atcatatact caactgtaca ataaaatgtt
      241 atctgcaatt ccgccatctg tttctttatc taagaccaca tttggtttaa ctggggatat
      301 aggatatttc attgttctat ccattataga ggattacgat acaaatactc tcgcatgctt
      361 aaattatata aagagtgttt taactgagct tgaaaagact gattttgcaa gtgtttcaaa
      421 caagtctgac tatattaatg gtcttctacc tttaattaat acactggtaa gatattatag
      481 gagaggaata gagaaggaac gtgttctaag gctagtatta agtttaggtg atacgctata
      541 taatgatgta agcgagagag ataatagtaa ttttggatat agttttggcc atggactatc
      601 aggtgtaatt tttacattaa aaaatattta taaagtgaca agacttaaaa aatataaaga
      661 attaatttta caactagttc ctagggagaa aatcaaaatt cattctttga agtggtgtag
      721 tggagaattt gggacattag ttaatcatcc ccaaagtgtt ccagagggaa ttgtagctag
      781 tttagataat gatacatttt gccatggaag tatggccata ataaattttt acatcgacta
      841 catgaaagaa atggatacta gtatggaatt ggagtcttta ttgtgtagtg ttgtaatgaa
      901 taaatcaaaa gaaggagagt atcgtatcgt ccaaacaagc aatttcccag atttttcttt
      961 gtatacaggt gtgactggta ttgcttatac ttttttaagg tatatcgcac tgaatcagaa
     1021 tgacaaaaag atagttatcc cctcattact tgaaatctag cttaatttat agttttgttt
     1081 ctaaaataga ggtgtccact cattaagcaa tataaaaata ccaagattga ctagtttaat
     1141 atgtaattct ataaaatatt tttaatagtg tagcttttcg ttgagataat aatataataa
     1201 agaaaagttc tattctaatt gctaaacggc ttgaggtata tgctactgtt atagaaatga
     1261 ttttaaacta aaatcaaaat tactccaaaa atagtattga ttttggttta atacaaaaca
     1321 tatgtaataa tgtgagtcaa caaaagtctg tttttgtacc atactatctt gaaaaatcta
     1381 ctaaattcaa attgagagga tgaattaaaa tgaataaaat atttatatat gcaggagtgc
     1441 gaaatcataa ctctaagact ttagagtata ctaagagact ttcaagtatc atttctagta
     1501 gaaataatgt tgatatatct ttcaggacac ctttcaattc agagctagaa atatctaatt
     1561 ctgattcaga agagttgttt aagaaaggaa ttgataggca aagtaatgct gatgatggag
     1621 gtgttataaa aaaagagtta ttagagtctg atattataat tatctcttct cctgtatatt
     1681 tacaaaacgt atctgtggac acaaaaaact ttattgaaag gattgggggg tggagccatc
     1741 tttttcgatt agctggaaag tttgttgtaa cattagatgt tgctgagagt aacggctctg
     1801 ataatgtgtc agaatatctt agagatatat tttcatatat gggaggacag atattacacc
     1861 aagtttcaat taccaattca ctcaaagata ttgcagaggc tcagttgatg gaggcaactt
     1921 ataaaattga agatgtactt gaagggaaaa ttaagtacaa aacaacggat tatcaagaaa
     1981 gagcttacca gacattaaaa ttaattttag aaaattatga ttccgaacat tttgagaaga
     2041 tgtattggga gaaaaaacgc ctttttgaag ctaatagttt agaggaatgg tattat
//
LOCUS       DAVKBK010000114         1983 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVKBK010000114 DAVKBK010000000
VERSION     DAVKBK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1983
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.114"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            39..779
                     /locus_tag="VWX69_001991"
     CDS             39..779
                     /locus_tag="VWX69_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9193268.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            782..>1983
                     /locus_tag="VWX69_001992"
     CDS             782..>1983
                     /locus_tag="VWX69_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193269.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIN"
BASE COUNT          646 a          256 c          363 g          718 t
ORIGIN      
        1 ggaacacttt tcaaaattaa gtgattggag gcaagaatat ggataaagat tatatattaa
       61 aagtgaaagg gctgtatcat caatttttac taggaaataa taaaacgttg caagtgctga
      121 aaaatgtttc tctttctgct tcgagaggag aatttataag tattctagga attagtggtt
      181 ctggaaagtc aactttatta aaatgtattt ctagtttgct tgaaccaaca agtggggaag
      241 taattttaaa tggaatcaac ccctataaaa tcagaaatgc aaaattgtca agtataagac
      301 gtaacgaagt atcttttata tttcaagcat acaatttaat accttccctg ccggtaatag
      361 aaaatatagc acttcctttg cgattatcac aaaaaaaatt aactattaaa aatgtagaaa
      421 acttactcaa aagaatgaag tttaatgctg gcttaaacga ttttgttgga actctgtctg
      481 gtggagaaca acagaaggtt gctatagcta gagcggttat tgctgatagt gatataatat
      541 ttgctgatga gccaactggg gctttagaca gcgtttctcg tgaagtaatt tttgaattat
      601 tgagagagtt agtaggggcg ggtaagtgtg taattatggt aacgcacgat atagaattgg
      661 cctcgaaaac tgatcgtgca ttaatattga aagatggaaa aattttcaaa gaacttcata
      721 gacctagcgg ggaagagttg tataaaatct tagaggtaca atcaactacg gaggaataga
      781 gatgctcaga ttagtttact atcaattttt acataataag aaacaatggt taggcgtttc
      841 accagtaatt tttgtttcga gtttagttat gggattggct gttaatgggg taattaatgt
      901 tgagaataat tcgcaagtat ttgtcggact tccagatcct aaaccaattt ttatgtttcc
      961 gatagtattc ggaggagtaa cattattctt tgtgctctct aacataataa atatgttggt
     1021 tgaaattttt agagatgatt acgaacttct ggaggtgttg ggagcaagtc tccttcaact
     1081 atcatttctt gtggggggac agatttttat catttcctcg attattagtt ttattgcata
     1141 tctatgctct atatttgtta cgtcaaatta ttattatttt ttacaatact ttttcgggga
     1201 aaatatatta cctgatatcc aatttcaaac gagtgctgtt ggatgtatca ttacagtagt
     1261 gttgatttca tttttagcct ttctaagtgg ttgcttttat acgttcaaga agattagaaa
     1321 taggaagagt tctaaaataa ggcatgttct ttcaatagta aaaagaatac tgctattggc
     1381 tggttttagt gttatctggt tgctttcttt gcaacaaatt ttccaagata gcacaatttt
     1441 agcgaaggcc cagataatat tcaatattgt aatcttagat attgtgatta tttatcaatt
     1501 atctcctttt atacagtcat gttttatcaa actactttct ataattatat ttagaaataa
     1561 ttttatgttc attgtttcga agtggaattt actatatcgt aagccttata taaaatctat
     1621 cagtgctgca attacaggag ctatattact aatttctagt tttcaaatga tttctcagaa
     1681 tatactatct caatttcaag atgacagtga tttagagcta aaagtggcat ttattgtcta
     1741 tgtaggagca ccaattttga tagtacttgc aaatattatt tcaattgcat ttttgtcatc
     1801 gcatcaagaa aggattgaga ttcagcaatt tgaaatttta ggaacttcta attaccagat
     1861 ggttaagatt aaagttggtg aggctatatt tttgacattt gttacttcat taattgcatt
     1921 tttacttaac attaaaatta tggctttaat atactactct ttagaggata ttttaataaa
     1981 tga
//
LOCUS       DAVKBK010000115         1888 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVKBK010000115 DAVKBK010000000
VERSION     DAVKBK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1888
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.115"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..244)
                     /locus_tag="VWX69_001993"
     CDS             complement(<1..244)
                     /locus_tag="VWX69_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193270.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFD"
     gene            complement(272..1033)
                     /locus_tag="VWX69_001994"
     CDS             complement(272..1033)
                     /locus_tag="VWX69_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU9193271.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELFFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(1033..1509)
                     /locus_tag="VWX69_001995"
     CDS             complement(1033..1509)
                     /locus_tag="VWX69_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9193272.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT          583 a          358 c          244 g          703 t
ORIGIN      
        1 tatcaaaatt actaaaaaaa attgtcttat caacttttat tttcttattt tcaaaaaata
       61 tatcatatag ttcatcttca gtaatttttc tatatttcgt tgcagtccaa ttagaaaata
      121 gcttgtaatc ataagaaaca ggtgtatgca aatgaattaa agtcttgtga aagctaccga
      181 atttctcttt ggaatttgtt agttcttgat aaacagactt tatcttgtta ttaaaccctc
      241 tcatttctat tctcctaaaa atatcaattg tttatttttc aagtaattca ttaagtctct
      301 tttcccccac ctgcaacatc tccttctcta cctgactcca ctccccaaag aataactctt
      361 gaagaacatc tgctgctgaa gttgtatttt cttttgaatc atatacacaa cttctatctc
      421 gttggtaaat ttgaattctt tcaaagatag ctagttcttc caattttcgt gtgttatcaa
      481 ctagatgatt tacaatgaaa tcatgatgtt cttttggagt tgcgcgtgct tgatttggat
      541 tgataatgta cagttcttca taacggataa gagtacttag atacgacaat tcaggctttg
      601 tcgcaattaa ggccaattgt acttcatatc ccttattttt caagagttgt gccgttttct
      661 ttggaacatc aattgttcgt aaagttccct cgatcaaaag attgtatccc aaactactca
      721 attttgttac taaagactct accatttttc ctgcaaaatc tttggtatat tctacactgt
      781 ctttgccata ttcttgctgc agttctaaat agtgtggatg ctgagaacga aaactatcac
      841 catctatgat aacaatattt ccttgaaatt ctttctgttt aatacgatga attgtagtct
      901 taccggcacc actttgacct ccaagcaaaa tcgctatagg ttgcttactg gacttttttc
      961 ctcttgtcag tgaacgaaga ttccttgcta aagcatgttt gaattcacta tcagtataat
     1021 cttggatttc cattaagcta ccatccgctt ttcagatatc tctaacatac gttcaattcc
     1081 atccaaatag ccactatatc tctctatttc atcaaaagtt tctactaaat agatattcgt
     1141 atgaatcaaa tcagaaagat catcactcat taaaatccaa ggattagatt catcatcaat
     1201 gctaattccc tgactatctt gatagcgata gagtcgagat aatagattag cacctctttc
     1261 tttcacaatt tcaattttta aagtcaattc ataatcttca acaggattga gcattttatc
     1321 ttctcctacg atatcgacat aagatacatt aaacttctga caaatgatgt ctattaattc
     1381 ggtagagact gaactcgttc cattttcata acgactcaga ctatttcgtg aaatacctac
     1441 aatccgtgca aattcgtgtt gtgttaagtc atgtgtttta cgtaaggatt ttatgttctt
     1501 tccaatcatg gcaaactcct ttatttttat aattcaatta tagcataaaa aagcataatg
     1561 caccaaaaat ggtgcattat ttcttgtttt tctatcctaa actttacttc tataaaagtc
     1621 acctaaagag ccataaatat ttattcttgt attaattttt tcgatgcgca aacgatatct
     1681 acaaatacat ctataacgat tcacctttta ggatttttat tgtcaaaatt gcctttatct
     1741 acaaagacaa aatgcttata aaatagtttg aaatcaagga ttatcgcctt tttcgttgta
     1801 gcaacactcc acatgtgatt attaggctat tagcaaagcg tatccaatac ctcaataaag
     1861 tgttgttttt actgatattt taactata
//
LOCUS       DAVKBK010000116         1863 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVKBK010000116 DAVKBK010000000
VERSION     DAVKBK010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.116"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..948)
                     /locus_tag="VWX69_001996"
     CDS             complement(<1..948)
                     /locus_tag="VWX69_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU9193273.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPFGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNLSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNY"
     gene            complement(961..1710)
                     /locus_tag="VWX69_001997"
     CDS             complement(961..1710)
                     /locus_tag="VWX69_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU9193274.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          647 a          343 c          208 g          665 t
ORIGIN      
        1 gtaattatct gaattatatt tcatccccaa tttatatatt cctactatct ttggctttcg
       61 ttccaatatt tgtttaacta tgaactgttt tctatttgtg tttgaaatat caatcgcttc
      121 tatcactggg gcatttattt ctataaattc tttttttaat tgtttagtat ctttgggaag
      181 acaatatcct ccaaatccaa aagaaagatt attataaaaa tttccaattc ttggatctaa
      241 acaaacacct tttattacaa cttcagcatt taaacttctc ctctcagcaa aagaatctag
      301 ttcattaaaa aaagcaacac ggagagctaa gaatgtgtta gaaaaaagct taattgcttc
      361 tgcttcagta ggagaaacta acataacatt tttaatattg gcagtactat gagtactaat
      421 cgaaaggaac aactctgcaa tttttcttcc ttcaactgtc tcatctccaa caactatgcg
      481 acttggatat aaattatcat atatagaaca accttctctc aaaaattcag ggacaaaaat
      541 gatatttttt gtatcaaaca gcctttttaa tttgtttgaa aagccgaacg gaactgttga
      601 ctttaaaata atctttccat taggttttac cctcagaatc ttcgataccg tttgttcgat
      661 ttcatatgta ttaaaactac caattttctc atcataatct gtcggaagcg caataatata
      721 ataatcaata ttatttttaa tttcagaaaa tgtatcaaaa aaagtaatat ttaagttatt
      781 ctcgcaaaaa aacttcataa gctcttcatt tttagatgga agaatgccct tttttaaatt
      841 atttattttt acagaatcta tatcatatgc aacaacttta tatttagatg caaatagtaa
      901 cgcgtaggcc agcccaacat gccccaaacc aattactgct atattcataa aactacttcc
      961 ttatttctta atccaaaatc taatagaata agctgcccca ttccttaaat acaactcttt
     1021 aatattgttt aaaagttttt caactgattt ccagattatc aaaatctgag atttatagca
     1081 caatattgat gatattctat caatataatg tttttcatca agttcctctt gatacatttt
     1141 taattcttta gtttttccca tataactaac catactacta tcacttacat atgggaagtc
     1201 ctcataatat attactttat aacgcataaa ttcaagcgcc cttccaatac tattcacaaa
     1261 aacatgatca acatggtcac caagtgaaag cggacaatat acgacacatt tgtcgtctaa
     1321 atgcattaac agctctttta tgatatcatt ctttaatgtg tcctcatttt ttaattcact
     1381 atagatatga cggtatagaa aattgccatt tctatctttc ctatagagac attcatagta
     1441 cgataagtgt ctaaaatcac actgtagacg ttcacaagct aacctgtctt ctttcttcct
     1501 ttcttcaatc ggatatttcc caaggttaca caacttatga aattgcttag cagagggctg
     1561 tagctgttgg ctcaaagggt aaccagaaaa tatagtaata acaagtacaa tttctccttc
     1621 tgaagttaat tttgaaatat aatcaccaca ggaaaaaatt gcgtcatcta aatgtggaga
     1681 taaaaagata tacttagtat tgttactcat aaccattccc tctacaattt atctaaaaac
     1741 tcactaagtg tctgattaaa ttccacatca tcaaaaaaat tcaccttatt cttaataatg
     1801 aatatttcgt taaataaaca tatatataaa tatttcaata tcctttcaat atcatcctct
     1861 aaa
//
LOCUS       DAVKBK010000117         1784 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVKBK010000117 DAVKBK010000000
VERSION     DAVKBK010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1784
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.117"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            302..1648
                     /gene="gdhA"
                     /locus_tag="VWX69_001998"
     CDS             302..1648
                     /gene="gdhA"
                     /locus_tag="VWX69_001998"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU9193275.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          565 a          330 c          353 g          536 t
ORIGIN      
        1 gtataaatat tgctttcctc caaaatggtc atagttttac tggcaaatct aacatatcac
       61 ggataaatta acaagtgatt tctgaattgc taaacatttt cttttcttat agcatacttt
      121 aagattttgt ctttgagaaa gatatttcca agaaaaacgt tcgttttttt atctattttc
      181 aaaaaaacca aaaaactgaa ttgaaagaat ttttagaaaa tttctgtttt ttctttacag
      241 tgaaaaaaaa ttctgctata atgtcttatg taataaaata tgacaataaa aggagaacga
      301 tatgacatct gctaaagaat atatccaaag cgtgtttgaa actgtgaaag ctcgtaacgg
      361 gcacgaggct gaattcctcc aagctgttga agaatttttc aacactttag aacctgtatt
      421 tgaaaaacac cctgagtata tcgaagaaaa tatcttggca cgtattactg agcctgagcg
      481 cgtggtttct ttccgtgttc cttgggttga ccgtgatgga aaaattcaag taaaccgtgg
      541 ttaccgtgtt caattcaact cagctgttgg accatacaaa ggtggacttc gtttccaccc
      601 aactgtaaac caagggatct tgaaattcct cggatttgaa caaatcttta aaaatgtctt
      661 gactggactt cctatcggtg gaggtaaagg tggatcagac ttcgatccta aaggtaaaac
      721 agatgctgaa gtgatgcgct tctgccaaag cttcatgact gaattgcaaa aacacatcgg
      781 accatcactt gacgtacctg ctggtgatat cggtgttggt ggacgtgaaa ttggttacct
      841 ttacggtcaa tacaaacgtc ttaaccaatt tgatgctggt gtcttgactg gtaaacctct
      901 tggatttggt ggtagcttga ttcgtccaga agcaactggt tacggtttgg tttactatac
      961 tgaagaaatg ctcaaagcta acggtaacag ctttgctggt aagaaagtcg ttatttcagg
     1021 ttctggtaac gttgctcaat atgctcttca aaaagcaact gaactcggtg caactgttat
     1081 ttctgtttct gactcaaatg gttatgtcat cgatgaaaat ggtatcgact tcgatctttt
     1141 ggttgatgtt aaagaaaaac gtcgtgctcg tttgactgag tatgcagctg aaaaagcaac
     1201 tgcaacctac cacgaaggta ctgtatggac ttacgctgga aactatgaca ttgctcttcc
     1261 atgtgccact caaaacgaaa tcaacggtga agcagctaaa cgtttggttg ctcaaggcgt
     1321 tatctgtgta tctgaaggtg ccaacatgcc gagcgacctt gatgccatca aagtttacaa
     1381 agaaaatggt atcttctacg gacctgcaaa agctgccaac gctggtggtg tagccgtttc
     1441 agctcttgaa atgagccaaa acagtcttcg cctctcatgg actcgtgaag aagttgatgg
     1501 ccgtctcaaa gacatcatga caaacatctt caacacagct aaaacgactt cagaaacata
     1561 cggtcttgat aaagactacc ttgcaggagc taacattgct gcctttgaaa atgtagcaaa
     1621 tgccatgatt gcacaaggta ttgtttaaga tttatttact caatcctcaa tcactacgat
     1681 tggggatttt tagcttgaat taaaaaattg gaaaatctaa ttaaataaaa tgaaatgaaa
     1741 taaaaactga acaaattgat tgcggaattc aaaccaattt ctaa
//
LOCUS       DAVKBK010000118         1747 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVKBK010000118 DAVKBK010000000
VERSION     DAVKBK010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.118"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            338..1689
                     /locus_tag="VWX69_001999"
     CDS             join(338..779,779..1689)
                     /locus_tag="VWX69_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU9193276.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
BASE COUNT          593 a          272 c          389 g          493 t
ORIGIN      
        1 cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta aattgtaaac
       61 tttagggatt ctctgaagtt atggatgtcg ttccaatatg tgtacgttgg aatgttagtg
      121 cttatatggg gggaacagaa tcctctcttg attgaagaca agttagccat taggctggtt
      181 tgtctctttg tcaactgtag tgggttgata taatagtatt agtgagtggg ataaaagttt
      241 catttagttt attcagtaca aatttaacgg gtcaagattt attgaactgc accccaatag
      301 ttagacagaa aaaatctaac ttttggggtg ttttattatg aaattgagtt atgaagataa
      361 agttcagatc tatgaactaa gaaagcaagg acaaagcttc aaacagcttt caaaaagatt
      421 tggtgtggat gtttctggtc taaagtacat ggtgaaatta attgaccgtt atggcataga
      481 aatcgttaaa aaagggaaga atcgtcacta ttcttctaaa ttgaaacaag aaatgatgga
      541 taaagcctta ctggaaggtt gttcacaaag aagtattagt cttgattatg ccctcccaaa
      601 ccaaggaatg ctttcatttt ggccggcaca atacaagaaa aacgggtata ctattgttga
      661 gaaaacaaga gggagaccag ctaaaatggg acgtaaacgg aagaagactt gggaagaaat
      721 gacagaacta gaacgactcc aggaggagaa tgaacgctta cggactgagg tggcctacct
      781 aaaaaagtta aaagagttag aggaaaggga cgaagcccta gagcgagaaa ggcagagaca
      841 gttagagaaa tggtttcagg aggatttcga ctagattttc ttcttgaaac agcacgttta
      901 gctcgctcga cttactatta tcagttgaaa caactggatg gggttgataa agataaagag
      961 attaaaaccg aaattcaggg cattgataat gaacataaag gcaactatgg ctatcgtcga
     1021 atccatttag aactaaggaa tcgtggtttt gtggtcaatc ataagaaagt tcaacggttg
     1081 atgagaattc ttggtttaac ggctcgaatt cgccgtaaac ggaagtattc ttcctaccaa
     1141 ggagagattg gcaagaaagc agagaatctc attcaacgcc agttcgaagc atcgaggcca
     1201 atggaaaagt gctatacaga tgtgacagag tttgccattc caaatagcac acagaaactc
     1261 tatttatcac cagttttaga tggttttaac agtgaaatca ttgcttatca tctttctact
     1321 tcgcccaact tagaacaagt gaagagtatg ttagaacaag cctttacaga gaaatactat
     1381 gagaatacga ttctccatag tgaccaaggc tggcaatacc aacacgattc ttatcatcgg
     1441 ttcctagaga gtaagggaat tcaagcatcc atgtcacgca agggcaacag cccagacaac
     1501 ggcatgatgg aatctttctt tggcattttg aaatcggaga tgttttatgg ttatgagaag
     1561 aactttagat ctttagaaaa ccttgaacaa gctattgtgg actacattga ttactacaac
     1621 aacaaacgaa ttaaggtaaa actaaaagga cttagttctg tgcagtacag aactaaatcc
     1681 tttggataaa ttatttgtct aattttttgg ggtcagtaca gtattaaata ccatgatctt
     1741 atgcgtt
//
LOCUS       DAVKBK010000119         1726 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVKBK010000119 DAVKBK010000000
VERSION     DAVKBK010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.119"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            34..105
                     /locus_tag="VWX69_002000"
     tRNA            34..105
                     /locus_tag="VWX69_002000"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:66..68,aa:Gln,seq:ttg)
     gene            267..1469
                     /gene="rpsA"
                     /locus_tag="VWX69_002001"
     CDS             267..1469
                     /gene="rpsA"
                     /locus_tag="VWX69_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU9193277.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1554..>1726)
                     /locus_tag="VWX69_002002"
     CDS             complement(1554..>1726)
                     /locus_tag="VWX69_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9193278.1"
                     /translation="ALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNI
                     KKERTKFVLSQP"
BASE COUNT          523 a          280 c          404 g          519 t
ORIGIN      
        1 ggggttcgaa tccctctctc tccatttcat taatggggta tagccaagcg gtaaggcaag
       61 ggactttgac tccctcatgc gttggttcga atccagctac cccagttctt aggtaataat
      121 caagataaaa agcaaaatat cttagggtat tttattttta taattgaaag acgtgaatga
      181 tatgaacatg tccttgcggg tgcttaggaa aaaaattata agtatgtcaa gtttaagaaa
      241 aacttgattg ttggaggatt ttttagatga acgaatttga agatttgcta aatagcgtta
      301 gtcaagttga gactggtgat gttgttagtg ctgaagtatt gacagttgat gcgactcaag
      361 ctaacgttgc aatctctgga actggtgttg aaggtgtctt gactcttcgc gaattgacaa
      421 acgatcgtga tgcagatatc aatgactttg ttaaagtagg agaagtattg gatgttcttg
      481 tacttcgtca agtagttggt aaagatactg atacagttac ataccttgta tctaaaaaac
      541 gccttgaagc tcgcaaagca tgggacaaac ttgttggtcg cgaagaagaa gttgttactg
      601 ttaaaggaac gcgtgccgtt aaaggtggac tttcagtaga atttgaaggt gttcgtggat
      661 ttatcccagc ttcaatgttg gatactcgtt tcgtacgtaa cgctgagcgt tttgtaggtc
      721 aagaatttga tactaaaatc aaagaagtta acgctaaaga aaaccgcttc atcctttcac
      781 gtcgtgaagt tgttgaagca gctactgcag cagctcgcgc tgaagtattc ggtaaattgg
      841 ctgttggtga tgttgtaact ggtaaagttg ctcgtatcac aagcttcggc gctttcatcg
      901 accttggtgg tgttgacgga ttggttcact tgactgaatt gtcacatgaa cgtaacgtat
      961 caccaaaatc agttgtaact gttggtgaag aaattgaagt gaaaatcctt gatcttaacg
     1021 aagaagaagg acgtgtatca ctttcactta aagcaacagt accaggacca tgggatggcg
     1081 ttgagcaaaa attggctaaa ggtgatgtag tagaaggaac agttaaacgt ttgactgact
     1141 tcggtgcatt tgttgaagta ttgccaggta tcgatggact tgttcacgta tcacaaattt
     1201 cacacaaacg gattgaaaat ccaaaagaag ctcttaaagt tggtcaagaa gttcaagtta
     1261 aagttcttga agttaacgca gatgcagaac gcgtatcact ttctattaaa gctcttgaag
     1321 aacgtccagc ccaagaagaa ggacaaaaag aagaaaaacg tgctgctcgt ccacgtcgtc
     1381 caagacgtca agaaaagcgt gatttcgaac ttccagaaac acaaacagga ttttcaatgg
     1441 ctgatttgtt tggtgatatc gaactttaat caaattgaaa attcacaaaa tcctttgttt
     1501 actaaacaag ggatttttct ggctctttgt caactgtagt gggttgaagt cagctaaggt
     1561 tgagaaagga caaatttcgt cctttctttt ttgatgttca gagcgataaa aatccgtttt
     1621 ttgaagtttt caaagttccg aaaaccaaag gcattgcgtt tgataagttt gatgagatta
     1681 ttggtcgctt ccaatttggc gtttgaatag ggtagttgaa gggcgt
//
LOCUS       DAVKBK010000120         1711 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVKBK010000120 DAVKBK010000000
VERSION     DAVKBK010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1711
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.120"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(655..1647)
                     /locus_tag="VWX69_002003"
     CDS             complement(655..1647)
                     /locus_tag="VWX69_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9193279.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT          592 a          276 c          216 g          627 t
ORIGIN      
        1 ttgattttgg agtagttata aaaactcatt cagataattt attatttgat tttgatacga
       61 ttcctgaaaa tataatagta gttgaccatt ttgaacttac aatcgaaaaa tggttaagta
      121 aaagtcaaca gttactatag tttgcaaatt atttacagaa agaacaaaaa atgctctgaa
      181 acactgattt caaggcattt tttgttagtt taaaattact cccattcttc ttttccaaac
      241 gtacaatata tccaaaacca ttcaaaatac tagattctat tttttataat atcactaaat
      301 ccacctaatt ataggacgtt ttcagatttt tagtcccgtc ccagtcccag taccggagaa
      361 atattgtttt aatataatat ctctttttgt cttctaagct cttaaaagca aaagaacaag
      421 taaagagtca agacaaggat aaaaagtcca tattagggca aataaaaagc tttaagacag
      481 atgacaaatc taagtcaaat aagaaagacc atagcaaagg tgcagagaga taaatattgg
      541 cggtcttcgg actgccttta tttttttatc catttttcaa atcaaattta ttcagactat
      601 atatgcacat atacacttaa attcatataa aaacatggct tgtaaaaaat tactttaatc
      661 acaataatcg catttaaaat tgtgatgttt gcaagctaaa ttacggactt cacttggaag
      721 ttttcccttg tatcttttat aatagataga aaatttgctg gcagatgaat atccaacaga
      781 ttctgctatc tcttttatag gtagttcagt gtttaaaaga agagtttcag ctacattcat
      841 tctttttctt tgagtgtact ctgtaatgct ttgacaatat ttttccttaa ataaattttt
      901 taatttagta ccactcattt tagatatttt ttcaagcgtg ccttgattta cattcgttgc
      961 aaaatgatca tctaagaatc ttgctacatc ttcaagtgct ttatcatcat caatttcaat
     1021 tttatatttt tttctattta agtatgtgtc aattactata cttatccatt catttgcctt
     1081 tgctttaaag aaaaaatcag cggcaggagc gtccatctta caatttaata tttccattgc
     1141 cactctttct aaggcctttg taagtattat ttgattcggt tgaagcaagg ttgaataaaa
     1201 agattctgga ttaatgttaa tagatgctaa atgtttttct attagctctt ttttaaaacc
     1261 aatggaaaca gcaagataac aacaattctc gtgtaataaa aaaacaaaat catcttttat
     1321 attatcaaaa tcaaaagtac ataaagagtt tgcggtaata gtttgatacg gattaaactt
     1381 ttctccgttt gcactgacaa tgtaacttga ataaattgaa acatagtctg acatactata
     1441 agtgctattt tgaactactt cctctttgat ataaaaatca tgtatatcga taatgaagct
     1501 gcctccttca taaaaccaat ataggccttc tgcataagtt gaattctctt ttttccaaca
     1561 aaatgtatga cctgcacttg aatacttctc attgttttta cattcatcta ctttcatata
     1621 atcttttaca aaatcataat atgacataac acactatccc ttttagacaa tattccaatt
     1681 agccttatta attcaaaact attgtattag t
//
LOCUS       DAVKBK010000121         1624 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVKBK010000121 DAVKBK010000000
VERSION     DAVKBK010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.121"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            84..491
                     /locus_tag="VWX69_002004"
     CDS             84..491
                     /locus_tag="VWX69_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9193280.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATPFKEVQKPLENFN
                     HIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            656..955
                     /locus_tag="VWX69_002005"
     CDS             656..955
                     /locus_tag="VWX69_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU9193281.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VWX69_002006"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VWX69_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9193282.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          554 a          324 c          284 g          462 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat tcaaaccaca tcagcgtcgc cttaccatac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttt attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag gcctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcggag
     1201 gaaaagtatt gtactatgat gattcaacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgataca aggaatcgat tcactggctt atctcgttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggatactat ataaacgctt tgagaacgga
     1441 aaactgactt ggcccagtac agaaaaggat gtcaaagctc tcgcacctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacccctact tctaaaacat tgttagaaat cgatttgact gtcctgatca atttgtcctg
     1621 ttct
//
LOCUS       DAVKBK010000122         1596 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVKBK010000122 DAVKBK010000000
VERSION     DAVKBK010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1596
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.122"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(123..1562)
                     /locus_tag="VWX69_002007"
                     /pseudo
     CDS             complement(123..1562)
                     /locus_tag="VWX69_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
BASE COUNT          409 a          333 c          265 g          589 t
ORIGIN      
        1 gcttgcaccc ctgtgtattc tggtagtggt gctacctgct ctggttcaac aatagcgcca
       61 gcttgtactc cagcatattc cggttcaact ttttcaggtt caacaatagc tccagcttgt
      121 actcctgtat attctggtag cggttctacc tgctctggat cacccttgtc agtcatgact
      181 gcctctggta acgctggttg aacttctggt acgcctttat cacttactac agcttctggc
      241 aactctggtt ggactgctga ctcacctttg tcggttaata cagctgctgg tagttcaggc
      301 tgaattgcgg gttcaacaat agctccagac tgtacttcct tatgttctgc accagtctca
      361 gcttgttcct ttataacttg agctttttta gtaccttttt cgactattct tgaaacaggc
      421 gcagtcgttg aagttgaaat aatttctcgt gaaacttctt cattgtttac agaaaatatt
      481 ctgacgattt caactttctt acctaatgca ccttcttgtt ttactcttac agttccttct
      541 gctaaatcag gattttcttg aatttcttct tgaaaatcta tttttgtttc tatagtttcg
      601 tcacgatata agagttccgg tttgttcaac tgacctgata gcacttcatc ctgtggattt
      661 aatgtattta ccccagtctt ttcctttgga gaaatcttct cctctttctt cgtttctaga
      721 ttcttatgtt cggctaattg ttcttgagaa tctgaagatt gtttctcttc ttttcttgga
      781 ttgattaatt cagtagagaa aggtttttca actacttgaa cttctgtcgg cttagttgaa
      841 gaaacaggtg tttgttcctg aatagcttgt actgttgatg gatggtctac aaaatttggt
      901 gtaacattat aatccacctt ttgttgtttt gtaggagtgg ctgctgattt ttcttgatta
      961 cttacttcaa aatcagaagt cgtttttccc tctttgatat atccaatata agtgtaacct
     1021 gaaatctctt taggaagagg taatttttct ccagaggtca attcatagtc cgtattgtaa
     1081 tttagcaaaa gatgattttc taaagcatgg actgaaacta agacaccatt tcccattccc
     1141 gcaaccaata ctaaatgtaa taccgtttta ttcttaacct ttttcttgga aacagcaaaa
     1201 attaaaattc ccagagcagc taagctagca ccagcaacta gggcttgcct ctcattcttg
     1261 cttccagtat ttggtaattc cgccagttga ttttgagaat ttaacttata aacaagataa
     1321 taagtttcat catcattctc cacgtatgtc ggaatatcat agacaagctg cttcttttct
     1381 tctgatgata gctctgaatc tgccacatat ttatagtgaa ctcccgcagt ttcttgagca
     1441 tccacagatg aactagctaa tacagacata aaaaataaac ttgaaatcgt tgcagataca
     1501 agtcctactg ataattttct aaatgaaaaa cgctcttgtt tttcaccaaa atacttttcc
     1561 attattcctc cttgaaataa aatttatata tgttac
//
LOCUS       DAVKBK010000123         1564 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVKBK010000123 DAVKBK010000000
VERSION     DAVKBK010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1564
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.123"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(105..1529)
                     /locus_tag="VWX69_002008"
     CDS             complement(105..1529)
                     /locus_tag="VWX69_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9193283.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
BASE COUNT          453 a          349 c          278 g          484 t
ORIGIN      
        1 gtttcaatct attataatac caaaaagttc gtattttttc tataattatt attattttat
       61 agcaaaaaaa taaaaccagg aaaacaattt cctggtttta cacgttattt cacatcaaaa
      121 acaatggatt tgacatttgt catcgcttca atgctatatt taattccttg cactccagct
      181 ccagaacctt tgacaccaag gaatgggaaa ttatctggac cacgctgggt tttattatta
      241 atgtggactg tacctacttc aagtttttca gcaatttcaa aggctttttt gaaatcattt
      301 gtaaagactg atgattgaag gccgaattca gattcgttgg caaaggcaat agcttcctct
      361 acactagcca cacgaatgat tggtaaaaca ggaccaaatg gctcttccca tgccactttc
      421 atatcttttg taacttggtc aaaaagcact ggccagagaa gattgccctc acgtttgatt
      481 ggtgtaagag cctgagcttc tttttcttgt gcatcctcaa tcaagcccca aatgaagtcg
      541 gctgaagcat tgtcaataac aggtgtaata tcagcattgt caaatggatc accaactgtt
      601 aatttagaaa cttcttcctg aagcaaagta gctaatttat ctgctacact ttcgagaaca
      661 atgacacgtt taatggccgt gcaacgttgt cctgagtagc taaaggctcc cgcaacaatt
      721 tgcttggcag catgttccaa atctgcatct tctagtacaa gagctgcatc tttcccacca
      781 agttccaaca tgataggacg cataccagct aaacgaccaa tacgttctcc aataggagtt
      841 gaacctgtaa agttgatgaa gttgacttct ttgtgctcaa tgatataatc cccaatttct
      901 gaaccacgac ctgtaatggt gttgaaaaca cctgccggaa tccctgcttc ttcaaatgct
      961 ttagccaaca agagtccaga aatggaacct tgtgttggtg gcttaaacat gaccacattc
     1021 cctgcaatca aggcaggtgc aattttagaa gcagataaat taactggata attaaaggga
     1081 gcaatcgcta gcacgatacc aactggttca cgacggacaa cagccagttt gtttttactt
     1141 gctgcctcaa aaccaccacc ttccattgct tgtccagtga tacggagacc ttcctcagca
     1201 gcataacgaa tcaagtctgc tgtacgcact acttctccaa ttgctgcttt aatccctttt
     1261 gctacttctt tggcaaggat agtaccaatt tcttccttat cgcgttctaa aatagctgct
     1321 gttttatgta aataagccgc acgttcaact gctgataaag ctcgccatgc tggcagggct
     1381 gcacgcgcag cttgcatagc ctcatcagct tcagtctgag tcatggctgg aactgtaccc
     1441 aattcttctt gattgattgg tgaataaatc gtaatttctt gttcagatga tttccatttt
     1501 ccatttacta aattctgata tcttgtcaaa ttcttgtcct cctgaaaatg attaagatat
     1561 attt
//
LOCUS       DAVKBK010000124         1555 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVKBK010000124 DAVKBK010000000
VERSION     DAVKBK010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1555
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.124"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(129..216)
                     /locus_tag="VWX69_002009"
     tRNA            complement(129..216)
                     /locus_tag="VWX69_002009"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Ser,seq:gct)
     gene            complement(223..296)
                     /locus_tag="VWX69_002010"
     tRNA            complement(223..296)
                     /locus_tag="VWX69_002010"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(260..262),aa:Ile,seq:gat)
     gene            complement(332..402)
                     /locus_tag="VWX69_002011"
     tRNA            complement(332..402)
                     /locus_tag="VWX69_002011"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(368..370),aa:Gly,seq:tcc)
     gene            complement(422..494)
                     /locus_tag="VWX69_002012"
     tRNA            complement(422..494)
                     /locus_tag="VWX69_002012"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(459..461),aa:Phe,seq:gaa)
     gene            complement(498..571)
                     /locus_tag="VWX69_002013"
     tRNA            complement(498..571)
                     /locus_tag="VWX69_002013"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(535..537),aa:Met,seq:cat)
     gene            complement(582..671)
                     /locus_tag="VWX69_002014"
     tRNA            complement(582..671)
                     /locus_tag="VWX69_002014"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(633..635),aa:Ser,seq:tga)
     gene            complement(682..755)
                     /locus_tag="VWX69_002015"
     tRNA            complement(682..755)
                     /locus_tag="VWX69_002015"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(719..721),aa:Ile,seq:cat)
     gene            complement(769..842)
                     /locus_tag="VWX69_002016"
     tRNA            complement(769..842)
                     /locus_tag="VWX69_002016"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Met,seq:cat)
     gene            complement(848..921)
                     /locus_tag="VWX69_002017"
     tRNA            complement(848..921)
                     /locus_tag="VWX69_002017"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(885..887),aa:Pro,seq:tgg)
     gene            complement(937..1010)
                     /locus_tag="VWX69_002018"
     tRNA            complement(937..1010)
                     /locus_tag="VWX69_002018"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(974..976),aa:Arg,seq:acg)
     gene            complement(1020..1105)
                     /locus_tag="VWX69_002019"
     tRNA            complement(1020..1105)
                     /locus_tag="VWX69_002019"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1069..1071),aa:Leu,seq:taa)
     gene            complement(1113..1184)
                     /locus_tag="VWX69_002020"
     tRNA            complement(1113..1184)
                     /locus_tag="VWX69_002020"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1150..1152),aa:Gly,seq:gcc)
     gene            complement(1207..1279)
                     /locus_tag="VWX69_002021"
     tRNA            complement(1207..1279)
                     /locus_tag="VWX69_002021"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1244..1246),aa:Thr,seq:tgt)
     gene            complement(1298..1379)
                     /locus_tag="VWX69_002022"
     tRNA            complement(1298..1379)
                     /locus_tag="VWX69_002022"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1343..1345),aa:Leu,seq:tag)
     gene            complement(1385..1457)
                     /locus_tag="VWX69_002023"
     tRNA            complement(1385..1457)
                     /locus_tag="VWX69_002023"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1422..1424),aa:Lys,seq:ttt)
     gene            complement(1482..1554)
                     /locus_tag="VWX69_002024"
     tRNA            complement(1482..1554)
                     /locus_tag="VWX69_002024"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1519..1521),aa:Asp,seq:gtc)
BASE COUNT          427 a          434 c          339 g          355 t
ORIGIN      
        1 gaaatttgtc ctttctcgag cttagctttt cttcaaccca ctacagttga caaagagcct
       61 taagtttacg gatctgaagt tttattgtct ctaaaaacaa aaaagagagt tacaaactct
      121 cattaaaacg gagaataagg gattcgaacc cttgcgccag ttacccgacc taacgattta
      181 gcaaaccgtc ctcttcagcc tcttgagtaa ttctccaatt aatgggcacg agtggactcg
      241 aaccaccgac ctcacgctta tcaggcgtgc gctctaacca cctgagctac gcgcccaagt
      301 taaaaaactt ggtaatttga acaaagttca aagcgggtga cgagaatcga actcgcgaca
      361 acagcttgga aggctgtagt tttaccacta aactacaccc gcataaatac tatcaataaa
      421 atggcgcgag acggaatcga accgccgaca catggagctt caatccattg ctctaccaac
      481 tgagctaccg agccttattg cgggagcagg atttgaacct acgaccttcg ggttatgagc
      541 ccgacgagct accgagctgc tccatcccgc gttaatataa aaggaggatg tgggattcga
      601 acccacgcac gcttttacac gcctgacggt tttcaagacc gttcccttca gccggacttg
      661 ggtaatcctc caatattcaa atggaccttg taggacttga acctacgacc actcggttat
      721 gagccgagag ctctaaccag ctgagctaaa ggtccgacaa gatcattata gcggcgaagg
      781 ggatcgaacc cccgacctcc cgggtatgaa ccggacgctc tagccagctg agctacaccg
      841 ccatgaatcg ggaagacagg attcgaacct gcgacacctt ggtcccaaac caagtactct
      901 accaagctga gctacttccc gagttaaata gaaaaatgca ccctagagga gtcgaacctc
      961 taaccgcctg attcgtagtc aggtactcta tccagttgag ctaagggtgc tccatattat
     1021 gccgaggacc ggaatcgaac cggtacgatc gttaccaatc gcaggatttt aagtcctgtg
     1081 cgtctgccag ttccgccacc ccggcctctc taagcgaacg acgggattcg aacccgcgac
     1141 ccccaccttg gcaaggtggt gttctaccac tgaactacgt tcgcactgtt ttcttctatc
     1201 taaaaatgcc ggctacatga cttgaacacg cgaccctctg attacaaatc agatgctcta
     1261 ccaactgagc taagccggct catttgttat atcttaatgc gggttaaggg acttgaaccc
     1321 ccacgccgtt aagcgccaga tcctaaatct ggtgcgtctg ccaattccgc caaacccgca
     1381 tatatgaccc gtactgggct cgaaccagtg acccattgat taaaagtcaa ttgctctacc
     1441 aactgagcta acgagtctaa aataacttgc gttatcttaa acggtcccga cgggaatcga
     1501 acccgcgatc ttcgccgtga cagggcgacg tgataaccgc tacactacgg gacct
//
LOCUS       DAVKBK010000125         1464 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVKBK010000125 DAVKBK010000000
VERSION     DAVKBK010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.125"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(29..625)
                     /locus_tag="VWX69_002025"
     CDS             complement(29..625)
                     /locus_tag="VWX69_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9193284.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(622..1104)
                     /locus_tag="VWX69_002026"
     CDS             complement(622..1104)
                     /locus_tag="VWX69_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEU9193285.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
BASE COUNT          565 a          241 c          168 g          490 t
ORIGIN      
        1 aatcagattc attaatttgt ataaactatt atttgtttga aatttcataa acccgtcctt
       61 cctctattaa aatcctttga gatttgctaa tcaattcttg attcaataaa ttatgagata
      121 catatataat agtagagctt tctttcatgg aaattaagcg tttagcaatc atatcaatac
      181 ttcttgcatc cactgttgat aaagtctcat caataaaaat ataatcccaa tttttagcaa
      241 aaattaagga taagcctaat ttgaattttg ttccagtaga tgctgtcata tagttatctc
      301 cgattttatt atcaaaaaaa gtattaattt gttctttatc ctcaaatgat agatggattt
      361 gaaaagaatc acacaacaac tgcaaatttt cttctatagt aaatggaaca accccaagct
      421 gattggtatc aaggtatagt acatctttgg agacacaatt ctttaaacca ctatcaaaag
      481 tctctagccc agctaaaagt tgtagaaggg tgctctttcc tgaaccattc tctccttcaa
      541 ctctgtaaat tcccttatca atctctagtg atatattttt caatatacat ttatcataac
      601 ttttagattc attttcaatt ttcataattt aattccctct atcaacgctg ctaaaattaa
      661 taaaagataa gaaatgatat accattttaa attacttttt atataaataa gtatattttt
      721 aattccccta tccttcaata atcggtataa aagatactga ctcatacctt gataccaaat
      781 aaaattcggt atttcaataa gagcatgagg taatattcct tttattgtag ctactattcc
      841 aatcatctga ccagatatac ccaattgtat tcctaaagat agcaaatcaa aaagttgcaa
      901 taagggcgaa atcggaaaac agaatagata tagcaaaaaa tttgtagaat ttgcctgtaa
      961 aactgtcaat gtaaattgta attccagttt cggaggtata gtagcaaaag tctcattttt
     1021 taatataaag cttaaaagta aacctagtaa aaaacagact atacaaaata acacatagta
     1081 aatcagaaaa ccactttttc tcatctaatg ccccctacta aaattacaaa tattatcaga
     1141 aaacaatata aaaccagaaa actccatctc aataaactaa ctgtaccttt aattaaaaat
     1201 agagctttct tataatagac ataggctata aaataattga atggaatcaa taacaaattc
     1261 aacaaaatac tttttatatc attactataa cttgtcaccg gaatcaaaca taacaacaat
     1321 gaaaattgta agaaagagat taaatgcgtc aacatcatta gttgtgcatt cttaaaaaag
     1381 aaattcattt tagaatgatt aagagcagat aattgaagta aagctagatc taccccaatt
     1441 gaggatttat gattccctat tatt
//
LOCUS       DAVKBK010000126         1375 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVKBK010000126 DAVKBK010000000
VERSION     DAVKBK010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1375
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.126"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(151..339)
                     /locus_tag="VWX69_002027"
     CDS             complement(151..339)
                     /locus_tag="VWX69_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193286.1"
                     /translation="MRLGGSLGQRRENEIFFGLLAILFIKPIIGIVKFFWMIISFAVQ
                     LLFYKILFKILDWLFKLI"
     gene            complement(299..481)
                     /locus_tag="VWX69_002028"
     CDS             complement(299..481)
                     /locus_tag="VWX69_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193287.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            complement(483..1262)
                     /locus_tag="VWX69_002029"
     CDS             complement(483..1262)
                     /locus_tag="VWX69_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193288.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLCAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT          455 a          295 c          200 g          425 t
ORIGIN      
        1 aacatatata ctgcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaaa
       61 tgattttact gcttatatta taccatatgg agagagatta aaaaactagc agtggagttc
      121 ctgctagctc tctgcgactt ggattaccat ctagataagt ttaaagagcc aatccaatat
      181 cttaaacaat atcttgtaaa acagcaattg aactgcaaag gaaatgatca tccaaaagaa
      241 tttcacaatc ccaataatcg gtttgataaa aagaatagca agaagaccaa aaaaaatttc
      301 attctctctc ctctggccta atgagccacc gagccgtatc cattagctta tctgcaataa
      361 aaagttttcc cagaccaaca acgacatggt cagctttctt tatcgttttc atcactttta
      421 caccttgcac ggtcaaaaag taattaccat aaattttatc aaaagctttg ataggattca
      481 tattactctc ctttaatgat ttcagcctct tttcggattg tttcaacatc ttcttgatat
      541 tgaacttcac tatagttgac tagcttggat aattctttct gcaagctttc ccccattggt
      601 ttcatagttg caaaggttaa accacctgca atgataccac ccaagatagg aataaatttc
      661 cctattcctt tggccagccc tcccttggta agattcacac caaatatttt taagactttt
      721 ttcaaaatag ggtaccaaag cgtctttgtt aaagctttat taggcactgt tttcattacc
      781 tgtttggcaa ttgttatacc accagcacat agcaaagcag cggttccatt cacccctaac
      841 attacgccta gataaagcaa gagggtattt tgagcatctt cactcaactc ctcgcgtgaa
      901 gcccaaagat cctcataacc ataaatataa cctaattctt gagccaattt cagagagaaa
      961 gcataaaatt gagccacatc agctggaatg gtaattgcca tagcaagccc tccagctaat
     1021 cctgccaaaa cagaagtccc actcgctaat aatacattgt cccgaataca agcattagct
     1081 acacgatcta atatttcttg agatagaaga gtcgttgtac cttgttccaa taaggtagga
     1141 atatcttttg gatccaattc tttggaaaac ttatccacta aaaatttcga acgatcaacc
     1201 ttaacaacag gtagtttcac cacttgttgc aatacttgca tagctaagtc ttgttcagcc
     1261 atatacaaac tccttatttc ttttttacac cttatcatat tatatttcct acaaaaaaag
     1321 cattttctaa ttagataaca ttaaaaaata cagaacccct tttttatagt aaaat
//
LOCUS       DAVKBK010000127         1341 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVKBK010000127 DAVKBK010000000
VERSION     DAVKBK010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.127"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            52..891
                     /locus_tag="VWX69_002030"
     CDS             52..891
                     /locus_tag="VWX69_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9193289.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            998..1273
                     /locus_tag="VWX69_002031"
     CDS             998..1273
                     /locus_tag="VWX69_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU9193290.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
BASE COUNT          444 a          211 c          288 g          398 t
ORIGIN      
        1 aattagaagt aaggaaacca atctgaatcc taaaatagaa agattgatac tatgacaaaa
       61 attaagattg taaccgattc atctgttact attgaacctg aactagtaaa gcaattagat
      121 attacaattg ttccattatc tgtaatgatt gataatgttg tttattctga tgcggatttg
      181 aaagaagaag gtaaatttct tcagttgatg caagaaagta agaatcttcc gaaaacaagt
      241 cagccacctg taggtgtctt tgctgagatt tttgaagacc tatgcaaaga tggtggccag
      301 attcttgcta ttcatatgtc ccatgctctt tcgggtacgg tagaagcagc acgccaaggt
      361 gctagcctat ctactgcaga tgtgactgtt gttgatagtt ccttcactga ccaagccctg
      421 aaattccaag ttgttgaggc tgcgaagtta gctcaagaag gtaaagatat ggaggcaatt
      481 ttatctcatg tagaagaggt taaaaaccat acagagcttt atattggtgt ttcaactttg
      541 gaaaatcttg tcaaaggtgg acgaattagc cgtgtaactg gcttgttgag ctctcttctc
      601 aatatccgtg ttgtcatgca aatgaaagac catgaattgc agccaatggt taaaggtcgt
      661 ggaactaaaa catttaaaaa atggttagat gagttgataa catcgctttc tgaacgtgct
      721 gtagcagaga ttggaatttc atattctggt agtgatgatt gggcaaaaga gatgaaagaa
      781 agcttacaag cttatgttga aaagccaatt tctgttttgg aaacgggttc cattattcaa
      841 actcacacgg gtgagaacgc ttgggctatt ttgatacgtt accactccta aaaaaataaa
      901 taaaatggga agaaatagcg tttttaactt gacctaaaag ggattttagg atatgattat
      961 atttgttaat tagaaattat ttggaggaat cattaacatg gcaaacaaac aagatttgat
     1021 cgctaaagta gcagaagcta cagaattgac taagaaagac tcagcagcag cagttgaagc
     1081 tgtatttgca gcagtagctg actatcttgc agctggtgaa aaagttcagt tgatcggttt
     1141 tggtaacttt gaagttcgtg agcgcgcaga acgtaaaggt cgcaacccac aaactggtaa
     1201 agaaatgaca attgcagctt ctaaagtacc agcattcaaa gctggtaaag ctcttaaaga
     1261 cgctgttaaa taatcagtct ttaaaaagcc tattgtatca agctttctag cttggtcagt
     1321 aggcttttta attatgaaat c
//
LOCUS       DAVKBK010000128         1335 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVKBK010000128 DAVKBK010000000
VERSION     DAVKBK010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1335
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.128"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(86..511)
                     /locus_tag="VWX69_002032"
                     /pseudo
     CDS             complement(86..511)
                     /locus_tag="VWX69_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(587..799)
                     /locus_tag="VWX69_002033"
     CDS             complement(587..799)
                     /locus_tag="VWX69_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9193291.1"
                     /translation="MIQPLLHADETSYRVLENDSHLTYYWTFLSGKAENQAITLYHHD
                     QRRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(808..1113)
                     /locus_tag="VWX69_002034"
     CDS             complement(808..1113)
                     /locus_tag="VWX69_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEU9193292.1"
                     /translation="MFPVETEEITYKRKKSKGKRQAILAQFDSEEVHHQVEESICPDC
                     QDDLKEIGASLQRQELVFIPAQLKRVDHIQHAYKCQTCSKNNPSDKIVKAPIPKAPL"
     gene            complement(1100..1294)
                     /locus_tag="VWX69_002035"
     CDS             complement(1100..1294)
                     /locus_tag="VWX69_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9193293.1"
                     /translation="MKIIQQQSAIIDSLTNELSLLCEQVAYLTQKLSGKSSEKSVCPF
                     GQLNLFEEESPSEKDGDVPS"
BASE COUNT          364 a          298 c          251 g          422 t
ORIGIN      
        1 agctccttca aaactttgag aaaataacca ccctcgcttt tttaaactga gcttaggcta
       61 aaagagtcca ctggactctt ttactccgtc ccataaccaa tgatttaatg gcgcattcag
      121 ctagattatt ggaaaggacc agatgtccgt ctttcaaaat agtcttaaag gtttctttat
      181 acttgaggct atacttgagg ctgtattcaa ttgcccttcc tagttttgaa cccgataaaa
      241 ctgactgacg ccggcaccaa gcaaagaaat cttccattag gggttggaga tgttcttgac
      301 gtttctgtag tcgttcatca gctggcaaag cctcccagtt tctttccaag gaaaataact
      361 gattacaata agctaaacct ttagctccta aggatgattt attcgcttgc ttgggggtcg
      421 cttcaaaaaa cttccttctc acatgtaccc aacatccaac aagttcagct tcttccagtt
      481 gacaataagc ttctagcggt tcgcagttta ccaagcttag cgtcgccttg ctcctaaacc
      541 ttggactgct atcgcatagg cagaactaga ggactaaagt cctaagttac tgccgcaaca
      601 tatcacaatg cacatagcca gaataatctc ctaggaattc ttgcactacc gaaccactcc
      661 gacgctgatc atggtggtac agcgtgattg cttgattctc agctttccca gacaaaaagg
      721 tccaatagta ggtcagatgg ctatcattct ctagaacccg ataggaggtt tcatctgcat
      781 gaagtaaggg ctgaatcaat agtctcgtta taaaggggct ttaggaatag gagcttttac
      841 aattttatca cttggattat tcttactgca tgtttggcat ttgtaagcgt gttggatatg
      901 atccactctt tttaattgcg caggaataaa gaccaattct tgtcgttgaa ggctcgctcc
      961 aatctctttt aaatcgtcct gacaatcagg gcaaatgctc tcttctactt gatgatgaac
     1021 ttcttctgaa tcaaattggg caagaatagc ttgacgtttc cctttagatt tcttacgttt
     1081 gtaggtaatt tcctctgttt caactgggaa catctccatc tttctcagat ggagactctt
     1141 cctcaaaaag gttgagttgt ccaaaagggc aaacactttt ctcagaggat tttccagaga
     1201 gcttttgcgt tagataagcc acttgttcac acagaaggga aagttcatta gtgagactat
     1261 caattatagc actctgttgt tgaatgattt tcaatcttct cccatagact ttcctcctta
     1321 tttcctaact ttatt
//
LOCUS       DAVKBK010000129         1255 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVKBK010000129 DAVKBK010000000
VERSION     DAVKBK010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.129"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            31..>1255
                     /gene="pcpA"
                     /locus_tag="VWX69_002036"
     CDS             31..>1255
                     /gene="pcpA"
                     /locus_tag="VWX69_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU9193294.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTF"
BASE COUNT          489 a          175 c          202 g          389 t
ORIGIN      
        1 attagaaaat aaatatgtaa ggaaatttaa atgaaaaaaa ctacaatatt atcattaact
       61 acagctgcag ttattttagc agcatatgtc cctaatgaac caatcctagc agatactcct
      121 agttcggaag taatcaaaga gactaaagtt ggaagtatta ttcaacaaaa taatatcaaa
      181 tataaggttc taactgtaga aggtaacata ggcactgttc aagtgggtaa tggagttact
      241 cctgtagagt ttgaagctgg tcaagatgga aaaccattca cgattcctac aaaaatcaca
      301 gtaggtgata aagtatttac cgttactgaa gtagctagtc aagcttttag ttattatcca
      361 gatgaaacag gtagaattgt ctactatcct agctctatta ctatcccatc aagcataaaa
      421 aaaatacaaa aaaaaggctt ccatggaagt aaagctaaaa ctattatttt tgacaaaggt
      481 agtcagctgg agaaaattga agatagagct tttgattttt ctgaattaga agagattgaa
      541 ttgcctgcat ctctagaata tattggaaca agtgcatttt cttttagtca aaaattgaaa
      601 aagctaacct tttcctcaag ttcaaaatta gaattaatat cacatgaggc ttttgctaat
      661 ttatcaaatt tagagaaact aacattacca aaatcggtta aaacattagg aagtaatcta
      721 tttagactca ctactagctt aaaacatgtt gatgttgaag aaggaaatga atcgtttgcc
      781 tcagttgatg gtgttttgtt ttcaaaagat aaaacccaat taatttatta tccaagtcaa
      841 aaaaatgacg aaagttataa aacgcctaag gagacaaaag aacttgcatc atattcgttt
      901 aataaaaatt cttacttgaa aaaactcgaa ttgaatgaag gtttagaaaa aattggtact
      961 tttgcatttg cagatgcgat taaacttgaa gaaattagct taccaaatag tttagaaact
     1021 attgaacgtt tagcctttta cggtaattta gaattaaaag aacttatatt accagataat
     1081 gttaaaaatt ttggtaaaca cgttatgaac ggtttaccaa aattaaaaag tttaacaatt
     1141 ggtaataata tcaactcatt gccgtccttc ttcctaagtg gcgtcttaga ttcattaaag
     1201 gaaattcata ttaagaataa aagtacagag ttttctgtga aaaaagatac atttg
//
LOCUS       DAVKBK010000130         1250 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVKBK010000130 DAVKBK010000000
VERSION     DAVKBK010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1250
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.130"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            40..837
                     /locus_tag="VWX69_002037"
                     /pseudo
     CDS             40..837
                     /locus_tag="VWX69_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(872..>1250)
                     /locus_tag="VWX69_002038"
     CDS             complement(872..>1250)
                     /locus_tag="VWX69_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9193295.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEEMVTSDFFEAWFQK
                     FLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAYIKK
                     NLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT          406 a          259 c          206 g          379 t
ORIGIN      
        1 ggtattatgg ttctgatttt ctagtataaa aaaattcaaa ctagaattct tcttagaaaa
       61 ggccgtttta agtgctatca ttgctcaaaa atggagctcg ctgagacttc tatcgtcaag
      121 aagaatcatc aaattccttg tatcatcaac caaaagattg ctcaaaagtt aattgaaaag
      181 atttctatga ccgacattga tcatcagttg tctatttcaa cttcaactgt cattcgcaag
      241 atcaataatt ttcactttga gcatgatttt tcgcgtcttc ctgagattat gtcctaggac
      301 gttgaaacag tccggggagt gactgtttca atcgggagat ggagatgagc tttattgctc
      361 aggactttga taaactcaat atcataactg ttcttgagag cagaacacaa gccatcatcc
      421 gaaatcccat gaatacaagg ctatcaagcg ctactggaag ctcattcaac aagatagtca
      481 gaaactgagt gataaacgat tttatcgccc tacttttcgt atgcacttga ctaataaaga
      541 aattctagat aaacttttga gctattccga agacttgaaa caccactata atctctatca
      601 gctcttgctt ttccacctct gtttcagact ttgtttaaaa ccttcctcaa agataaagag
      661 aaaatcgtca acgcccttca attaccttat tccaacgcca aactggaagc caccaataat
      721 ctcatcaaac ttatcaagca caatgccttt ggttttagga actttgaaaa cttcaaaaaa
      781 gaaaggacga aatttgtcct ttctagatct tcgctttctt caacccacta cagttgacaa
      841 agaaccgaaa aatgtctcgc ctctaatata gtcaattgaa acaagaacaa gagaaaagag
      901 cctcgtaaaa ggtattgcaa cttggtaata cctttttgag gttctttttg atataagccc
      961 atgttttctc aataggattg tactcaggtg agtagggagg aagaggtaaa agtttatgcc
     1021 caaactcctc gcataaaagt tctaacttac ccattctatg gaatcttgca ttatccataa
     1081 taataaccga tggtgtggtt aatgttggta agagaaactt ctgaaaccaa gcttcaaaaa
     1141 agtcgctcgt caccatctct tcgtaagtca ttggagcgat taactcacca tttgttagac
     1201 ctgcaaccaa agaaatcctc tgatatcttc ttccagatac tttacctctt
//
LOCUS       DAVKBK010000131         1191 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVKBK010000131 DAVKBK010000000
VERSION     DAVKBK010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1191
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.131"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..851)
                     /locus_tag="VWX69_002039"
     CDS             complement(<1..851)
                     /locus_tag="VWX69_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9193296.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
BASE COUNT          402 a          153 c          206 g          430 t
ORIGIN      
        1 tataggtttg aaaaatcatt aatttctttt tcgagtattt taactaatgc ctcttctttg
       61 gttagtcgta ataaagttat tcctttatca atcaaatcgg agttatgttg tagtattccc
      121 aagcgtactt gagagaatcc aagaatatcg tatattttta attcttctgc taataccaaa
      181 agttgtaggg tgattgtttc acattctttg aataaatgat gttgaaaata tacagtggag
      241 agattggcta aaaaagatga taaaaatgct tttgtttctc ggaagtattt atatttctcg
      301 atggttttca taattctatc aataagaagg ggaagatttt cagaaggaaa gaaaaagaga
      361 atggttccaa gcaatttcaa atcactaatg taccatgtat ccataggttc aagatagtcc
      421 caaatttctt catacaaatc tttcaagacg tggttgtttt tgaatccttt agttcgtaac
      481 tctgtgacaa tttttgtatg acgatagata ttttgaatag gaacatcgtg atgtgtctta
      541 agatattttt gacatttctc agtgagttca accatttttc tagtatcttg aaaagtagac
      601 ggattttggc tctctacaat aatatctcgc cttttactag gatggtattc gttgcatata
      661 tacttgaatt ctgccaagct catatcaatt tgttcaagaa gaaataccat gttttcaaaa
      721 ctgggaataa ctttaccgtg ttcaatattt gttagagttg ttcgatgtat gacttgtcca
      781 catacatctt gttgggtcaa tccttttgac tttcgaattt ctttaaaaat ttgtccataa
      841 tcccatctca tattgttcct cctaggtaaa tgtgaatatt ttctacattt ataaaaaacg
      901 tagaaaaagg tggtattatt atatcaaaaa ggagggaaaa agtcatgggc tttaaaaaat
      961 atttgaagaa tttaccgaaa aactctggat ttttgatttg gagttggatt caacttatct
     1021 ggtttgaaac atggttttgg ggataaagaa attagagtct atatataata agtaaaggag
     1081 gaatttgtat gatataccat cgtttagaat aagtctatat ttaaaataga agttataagg
     1141 aatcttcttg aataaaaaat gaaaggaaac agaaaaaatg aaaattaaga a
//
LOCUS       DAVKBK010000132         1175 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVKBK010000132 DAVKBK010000000
VERSION     DAVKBK010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1175
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.132"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..>1175)
                     /locus_tag="VWX69_002040"
     CDS             complement(<1..>1175)
                     /locus_tag="VWX69_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9193297.1"
                     /translation="MTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARSMGILFS
                     NIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVGGVVDIG
                     TILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLIYSVETE
                     ALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLFAPIIIL
                     IFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYLNRVNDIWLEN
                     EENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPGQRIALVGQSGSGKS
                     TLSKILSGLYKIDTGKILFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLK"
BASE COUNT          437 a          194 c          132 g          412 t
ORIGIN      
        1 ctttaaagtt atattatcaa gaatacttcg gttcaataaa aatgaatcct gtggaactac
       61 tcctaaattt tgacttaata tttttttatc tatttgatta atatttacac catcaaataa
      121 aatttttcct gtatcaatct tatataatcc tgatagtatt tttgataacg tactttttcc
      181 tgaccccgat tgaccgacta gtgcaattct ctgtcctggc tcaatagtca aatttaaatt
      241 ttctattaca ggagctgagt ctttggaata agagaaagat aggtccttaa tatctattct
      301 accttctaaa gaacactttt taagaccatt ttcaacattc tcttcatttt caagccagat
      361 atcatttact ctatttaagt atcctgctgc caaaatatac tgcgtataag cattaaatat
      421 tgagatttct gaactaaata aaattgatgc catggtttga aatgcgacaa cctcacccaa
      481 taaaattttt ccatttaaaa cattatcaag tccaaaaatc aatataatta taggagcgaa
      541 caattgaaat acattagtag ctgaattgta taaaatatgc acaatacttc gttttttata
      601 ctttgtcaat acgtttttta aatacttaga ccagttttca tatatttcat cttctaatcc
      661 cgatattttt attgaagaaa tagtatttaa tgcttctgtt tctactgagt aaatcaatga
      721 ttgttcttgt aattctctat taaccgtatc atacattatt tttctagtac taaacagaaa
      781 caaaaaattg attaaactca atataagagc tataattgat aatgtttttg aactaagaaa
      841 catatatatt acaacactta gaatagtccc gatatctact actcccccaa caacttggtt
      901 agtaaatagc tccctaaaac cactaagact agaaattctg tataaaatat ctccttttgc
      961 cctgagttca aaaaaactat atggtagttt aagcaaatgc ttaaatgtaa aactttcaat
     1021 atctctacta aaaaatatat tagaaaatag aattcccata ctcctagcca agatagaaat
     1081 aagatacaaa caaagtagag aaaataaaat taaaaacgag gtttgaaaag aaaatgtatt
     1141 ccctaatgca gaattaataa actttgaagt catta
//
LOCUS       DAVKBK010000133         1123 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVKBK010000133 DAVKBK010000000
VERSION     DAVKBK010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.133"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..664
                     /locus_tag="VWX69_002041"
     CDS             <1..664
                     /locus_tag="VWX69_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9193298.1"
                     /translation="LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPII
                     PESITVADLVSRGRFPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQ
                     RVWIALALAQDTSILLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTA
                     RYADYLFAIKEGKLVAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHV
                     NS"
BASE COUNT          463 a          184 c          176 g          300 t
ORIGIN      
        1 actcattaaa accttgtctc gacttataaa gccattagag ggagaagtat tgcttgataa
       61 taaatcaatt aattcttata aagaaaaaga tttagcaaaa cacatagcta tattacctca
      121 atctccaata atccctgaat caataacagt agctgatctt gtaagccgtg gtcgtttccc
      181 ctacagaaag ccttttaaga gtcttggaaa agatgacctt gaaataataa acagatcaat
      241 ggttaaggcc aatgttgaag atctagcaaa taacctagtt gaagaacttt ctgggggtca
      301 aaggcaaaga gtatggatag ctctagccct agcccaagat acaagtatcc tacttttaga
      361 tgagccaact acttacttgg atatctcata tcaaatagaa ctattagacc tcttgactga
      421 tctaaaccaa aaatataaga caaccatttg catgattttg cacgatataa atctaacagc
      481 aagatacgct gattacctat ttgcaattaa agaaggtaaa cttgttgcag agggaaagcc
      541 tgaagatata ctaaatgata aactagttaa agatatcttt aatcttgaag caaaaattat
      601 acgtgaccct atttccaatt cgcctctaat gattcctatt ggcaagcacc atgttaactc
      661 ttaataattg aatattggaa ttcatttaaa agtcgcaaat tttgaactga ccctcaaaag
      721 ttaggccaaa aaactaacta aaggaggtca gttttttaat ggcaaataca gcacagaatt
      781 taagataaaa ttagtaaaag aatatcatga atgaaaaata ggatatagag aataacagca
      841 atattaaaaa gatcaggact gataataaac aaaaagaaag tacaacgact agttcaaaag
      901 ctaaaacttc aagtaaaaag ttattcaaga aaatctagaa aatactcatc ctacaaagga
      961 caggtaggaa aaatatcaga caacaaaata aaaagaaata tttattaccg aaaaaaaggg
     1021 gaaatcgagt taagtaccaa caggctcatc tattccaaaa agatatttac tcgatggaaa
     1081 aactcctaga attagtgcta caaatattga caatggtatc tta
//
LOCUS       DAVKBK010000134         1083 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVKBK010000134 DAVKBK010000000
VERSION     DAVKBK010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.134"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            119..>1083
                     /gene="pavB"
                     /locus_tag="VWX69_002042"
     CDS             119..>1083
                     /gene="pavB"
                     /locus_tag="VWX69_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU9193299.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLE"
BASE COUNT          370 a          198 c          224 g          291 t
ORIGIN      
        1 taatataagt gttttataag agggatttaa gaaaaatttt aactttttct tagtcctttt
       61 taatttcagg agattatact agagtcatca aataaagaaa gactctaagg agaatcctat
      121 gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca gtgtcggtgt
      181 tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa gttctgtacg
      241 tgccgatgtg gtcaatccga ccccaggtca agtcttacct gaagagacat cgggaacgaa
      301 agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga aacctgaggg
      361 cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag tgagcgagga
      421 aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc aagaaaatcc
      481 agagctaaca gatgccttaa aagaaactgt agatacagct gatgtggatg ggacacaagc
      541 aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa atacaaaaga
      601 cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc ctttcactgc
      661 tggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt taactcgtct
      721 attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta aaaatcctgc
      781 tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag acttaaatgg
      841 caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta atggtactca
      901 aacttataaa gctactgtta aagtttacgg aaataaagac ggtaaagctg acttgactaa
      961 tctagttgct actaaaaatg tagacatcaa catcaatgga ttagttgcta aagaaactgt
     1021 cgaaaaagct gttaaagata acgttaaaga cagtatcgat gttccagcag cctacctaga
     1081 aaa
//
LOCUS       DAVKBK010000135         1038 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVKBK010000135 DAVKBK010000000
VERSION     DAVKBK010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.135"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..>1038)
                     /gene="lanM"
                     /locus_tag="VWX69_002043"
     CDS             complement(<1..>1038)
                     /gene="lanM"
                     /locus_tag="VWX69_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEU9193300.1"
                     /translation="RGKLNDIKFGKGDTHSQGKTVLILFFDDAKIVYKPKNLIINNSL
                     NTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLPEYYYNFGVLLAFI
                     YLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDTLFHRVTRTLLLPT
                     EGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNLPVRDG
                     DIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSYASVL
                     SFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTNINEIY
                     DDFGNHFISLH"
BASE COUNT          347 a          195 c          120 g          376 t
ORIGIN      
        1 tgatgtaggg aaataaaatg atttccaaaa tcatcgtaga tttcattgat atttgtatct
       61 gtataaaaaa tcggaatatc taataacctc atttgttcac attcgcttgc tacaatacct
      121 tgattagaaa acttattgct ccagagattt tccaatgctt tttctctatc taacatttct
      181 tcataaaaat caggatgata taaaaaagat agtactgaag catagctatt tgtgtctcta
      241 aaaagtaccc ttgtctttaa accatacaag tttgctttta atagcatttt aaattcttct
      301 gttttattta actcttcaaa tatcagataa aaatccctaa aacctttttt gaaatctttt
      361 atatacttat caaattctat atcaccatcc cgaacaggca ggtttttccc accttcaaaa
      421 tcaattttcc caatatcaaa ctttacctta tcagtattta aattaattaa aacttgacca
      481 ttaaaagcat ccttcttaaa atttcctgta agagcactca tctcaacatc aagaccatcc
      541 tcccttttta ctccctctgt tggaagaagc aaagttcgag tcaccctgtg aaacagggta
      601 tccagcaaac tctgaccagt tttatcatca aatagaggtt gctgtaacat tgtttcaaag
      661 tctattatta caggcatatc tccataggaa attaaatttt caaaatgtat atcactccca
      721 ttaaataaat atataaatgc taaaagcaca ccaaaattat aataatattc aggtaatttt
      781 ttcttttgct ctagaggtag ataatcaata aattcttcat agctgtgatc cgaataagca
      841 atagttcgag gtattcttat cctaattttt tcatcaacct ttcggatata ctcagcaata
      901 gtatttagtg agttattgat tattaaattt ttaggcttgt aaacaatttt cgcgtcatca
      961 aagaagagta tcaaaacagt ttttccttgg ctgtgtgtat caccctttcc aaattttata
     1021 tcatttaatt tccccctt
//
LOCUS       DAVKBK010000136         1028 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVKBK010000136 DAVKBK010000000
VERSION     DAVKBK010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1028
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.136"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            56..967
                     /locus_tag="VWX69_002044"
                     /pseudo
     CDS             56..967
                     /locus_tag="VWX69_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          332 a          180 c          216 g          300 t
ORIGIN      
        1 taatttatag aaatatttta gcagctaagg tgtactgtta tagattcaat acactataga
       61 ctgtaatcaa acaacgattt ggcgaaatgt aaaaaaatat gaggagttcg aactcgactc
      121 tctccttcaa gaaacacgtg gtggccgtaa ccatgcatat atgacgattg aggaaaagaa
      181 agtctttctt gcccgccatt tgaaggctac agaggcagga gaatttgtta caattgatgc
      241 cttatttcag gcttataaaa aggagttagg tcgttcctac acacgtgatg ccttctatca
      301 actgttgaag caccatggtt ggcgaaatat tatgccacgt ccagaacatc ctaggaaagc
      361 agacgctcaa accattgtcg cgtctaaaaa taaaatctca attcaagaag aaaagaaagc
      421 gctttaaaag cagtagacgt tttcgtaagg ttcgcttgat gtaccaagat gaggctggtt
      481 tcggtagaat cagtaaactg ggatcttgtt gggctccaat aggagtaggt ccacatgtcc
      541 atagtcacta tatacgagaa tttcactatt gttatggagc tgttgatgcc catacaggcg
      601 aatcattttt cttaatagct ggtggatgta atactgagtg gatgaacgcc tttttagaag
      661 agctttcaca agcttatcca gatgattatc ttttactcgt tatggacaat gctatatggc
      721 ataaatcaag taccttaaag attccgacta atattggttt tacctttatt cctccataca
      781 caccagagat gaacccattg aacaagtgtg gaaagagatt cgtaaacgtg gatttaagaa
      841 taaggccttt cgaactttgg aagatgtcat gaatcaactt caagatgtca tacaaggact
      901 ggagaaggag gtgataaagt ccatcgttaa tcggagatgg actagaatgc tttttgaaag
      961 cagatgagta ttatatgcaa tttctttata taaaaagacc ggattgctcc gatctttcaa
     1021 tagttcat
//
LOCUS       DAVKBK010000137          999 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVKBK010000137 DAVKBK010000000
VERSION     DAVKBK010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.137"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            238..837
                     /locus_tag="VWX69_002045"
     CDS             238..837
                     /locus_tag="VWX69_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193301.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYTTIDKTSDATALLKLKLNNVDNQPATEVLSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     VGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
BASE COUNT          364 a          144 c          190 g          301 t
ORIGIN      
        1 ttaatatttg gagaagagga tggccatctt ctccattttt atgtgcagag ttatagtgac
       61 ttgatgctgg gaaagtacac tgtgactgct aatactcaat gaaaatcaaa gtgcaaacta
      121 ggaagctagc cgcaggctgt acttgagtac gtcaaggtga agctgacgtg gtttgaattt
      181 gattttcgaa gagtataaaa cattcctaga agttgctttg atttccctaa tctatttatg
      241 caaattttat gttattttac tataacagtt gttgctaagc caaataatag tggggaagtt
      301 catttagacg taagcattga agataatcag ggaggtagtg ggcataattt cagttctgtt
      361 tcaagtagct cacaaacagc taaatatgaa gaaactggtt ataataacaa tttatcatta
      421 tatacaacga ttgataaaac gtctgatgca acagctcttt tgaaattaaa gttgaataat
      481 gttgataatc aacctgctac tgaagttctt agttcaggaa ttactgtaaa attaaatgct
      541 aaagataatg ctggaaactg gacaagtgct tcgaataaaa aagaaataac agtaaaaatt
      601 gtttctgcta aaccgacata tccagacaaa atcttagtga aaaatcctga taatataaaa
      661 gatacagaaa aaaatgccat tattgaaaaa ttgaaagagg caaataaaaa ttatccagta
      721 ggagctccaa cctttgctaa aggtgaagga gagcatgcaa atgatattgt agcaacttat
      781 tcagatggta caacttatta tgtaccgtta aatgatgtga caaaatatgc gaggtagtgg
      841 ctgtaccact cacttattca cctccccgtg atttgtagta gtgataggct ttctaactat
      901 tattataaaa caaaataaag agcacaacac tttttcattc tgtgttgtgc cttgagtgaa
      961 acgaaaggaa tgaattataa atatgaaaag tatagtcac
//
LOCUS       DAVKBK010000138          972 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVKBK010000138 DAVKBK010000000
VERSION     DAVKBK010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.138"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(78..950)
                     /locus_tag="VWX69_002046"
     CDS             complement(78..950)
                     /locus_tag="VWX69_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9193302.1"
                     /translation="MIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQT
                     MLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKD
                     GFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLI
                     VSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPI
                     ACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSP
                     YLIYLLIKMNRRNI"
BASE COUNT          354 a          167 c          137 g          314 t
ORIGIN      
        1 tatttttata tttatatttt ccaagattat tttttcatca taaccgcagg taagattatt
       61 tgaccacaga cctttcatta tatattcctc ctgttcattt ttattagtaa gtatattaag
      121 tatggtgaac ctaacaagcc agttacaaca cctactggat atctagctgg taaaatattt
      181 tgagagaata tgtctgataa caaaactagt aaaattccaa ccaatccagc taatattggg
      241 cttcttttct tgccaatatt taaggctatg ggaccagcta aaaaagatat acaagctatt
      301 ggtcctgtaa ttgaagtaga aaaagcagtt aaagatacag cgcaaaaaat taaaacaagc
      361 cttgaaagct cgggatttgc tccaagtccg attgctattt cttcaccaag ttcaataatt
      421 tctagtcttt tattaaaaaa taaaactaat atagtagcaa taatacttac tattagaaca
      481 agaggtatgt catctaactt tgtaaaagat aaagagccac tgagccatct cataacttct
      541 tgtaattcat atcttgctac tttcaacaat aaaaatgagg tgcctgctct tgtgacagct
      601 tgaaaaccaa tacctaatat tatcagtctt gctgctgaaa aaccatcttt tttagctagt
      661 aaaaataata ttaaagatga tgttagtcca caagttattg aaataattcc agtagttaaa
      721 ctatttgttt ttaataccaa tatgcaaaag accgctgcaa tagatgaaga acttgtgaca
      781 ccgattatat caggacttgc aagaggattt cttaacatag tttgaaagat aaatcctgcc
      841 aatccaaaag accagccagc tataattcct gctaataatt ttggtaatct aatttccata
      901 atcgaaaaac tagctccagg aacagtttca ctatttaaga ctttaatcaa agttgaaaaa
      961 gaataacttt ca
//
LOCUS       DAVKBK010000139          869 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVKBK010000139 DAVKBK010000000
VERSION     DAVKBK010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.139"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..815)
                     /locus_tag="VWX69_002047"
     CDS             complement(<1..815)
                     /locus_tag="VWX69_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016648332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9193303.1"
                     /translation="MALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEK
                     ASFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVG
                     IILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESF
                     KSFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILL
                     ELIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNV"
BASE COUNT          299 a          168 c          120 g          282 t
ORIGIN      
        1 ttgacattac catgcactaa tttgtctttt tgcatatctt cgtaaagcgc ctctaaagta
       61 tctactgcat aatttccttg agaaatatac atggagtacc acatcattct catgaatgaa
      121 acaaagagaa ctcctgataa aaataaaatc atgataagct caagtaaaat cacctttgcg
      181 ctagctaagc tagtcataaa ataaactata ggaataatta aaattgcaat cagtccaaaa
      241 aataaccatt gatacaaaac ataaggcctt ttacaagata gggaataatc ataagcatac
      301 tttgagtaat cttttatcgc cttataaaag cttttaaaag actctacatt tgctttaaat
      361 atttttacaa cttgcattcc tctcacgtac tcaacagttt cagcacttag tttagatagg
      421 gattcttggt atatcttcat aaattcttgc tcgcccatca ttgcccctaa aattaagcca
      481 ccaattatag taagagcaag caaaattatg ccaaccctta tacttactat aaagccaagt
      541 gcaagtacaa gtacgggtgt gattattgcc tgagaactat cgggaatcat gtgtgctacc
      601 acctgatgag tttgtgctgc attatcatct atgatctttc ttatttgacc agatggattt
      661 aagtcaaaga acctaaaact tgctttttcc agaccatcga ttcccctttt tcttaaattt
      721 gtttcaagcc taaatcccaa gatatgtgaa aacattcctg agacaaaata aaatatcgct
      781 ccacttgtta gtgtaataac agattttaat gctatactct ctgcaccgga taagtttgaa
      841 ttaattatta acttatctag aaatttgta
//
LOCUS       DAVKBK010000140          843 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVKBK010000140 DAVKBK010000000
VERSION     DAVKBK010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..843
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.140"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(1..843)
                     /locus_tag="VWX69_002048"
                     /pseudo
     CDS             complement(1..843)
                     /locus_tag="VWX69_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          259 a          152 c          171 g          261 t
ORIGIN      
        1 aggatgaacc tgcttaagat tgtcctcaat aagtccgaaa aatttctctg gttccttatt
       61 atagagctga tagtggtgtt tcaagtcttc tgaatagctc aaaagcttgt ttaaaatctc
      121 tttattggtt aagtacatac gaaaagtaga acgataaaat cgcttatcac tcagtttacg
      181 gctatcctgt tgaatgagtt tccagtagcg cttgatagcc ttgtattcat gagactttcg
      241 atgaaactga ttcatgattt ggacatgcac acgactcata gcacggctaa gatgttgtac
      301 aatatgaaag cgatcaagaa cgattttagc attcgggagt gaaacagtct gagagactgt
      361 ttcagcctga gcctagaaat ttgaaagcga agttgtctag ctaagtcata gtaaggacta
      421 aacatatcca tagtaatgat tttcacttga caacgaacgg ctctatcata tttaagaaag
      481 tgatctcgga tgatagcttg tgttctacct tcaagaacag tgatgatatt gagcttttca
      541 aaatcttgcg caataaagct catctccatc tcccgattga aacagtcact ccccggactg
      601 tttcaacgtc ccaagacata atctcaggca gatttctaaa attacactca aagtggaagt
      661 cattgagctt tcgaatgaca gttgaagttg agatggaaag ctgatgggca atatcggtca
      721 tagaaatctt ttcaattaac ttttgagcaa tcttttggtt gatgatacga gggatttggt
      781 gattcttctt gacgatagaa gtttcagcga ccatcatttt tgaacagtga tagcacttga
      841 atc
//
LOCUS       DAVKBK010000141          811 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVKBK010000141 DAVKBK010000000
VERSION     DAVKBK010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.141"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            231..>811
                     /locus_tag="VWX69_002049"
     CDS             231..>811
                     /locus_tag="VWX69_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU9193304.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCL"
BASE COUNT          289 a          136 c          170 g          216 t
ORIGIN      
        1 taccttagtc aagaattaga tgtttcacta tgtttgagta agttgatgat ttcatttgat
       61 aacaggtttg aaactgttag gctaggtggc caaggctaat catagccttg gtttagctga
      121 aaaaacaggt tcaagggttc ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca
      181 cctctgtgct atacttgttg ttcaccacaa acacaaggaa aggcacagag atgcaagaac
      241 attatacccc aaaagggaaa catttgacaa tagataaccg tcgcttgatt gagcggtgga
      301 agaatgaaaa taagtccaat cgtgaaattg caggcttgtt aggaaaggcg cctcaaacga
      361 ttcatactga agtcaaaaga ggtacaactt tacaacaagt gagaaaaggg ctatacaaaa
      421 aggtctattc tgccgattac gcacaaactg tttaccaatt caatcgaaaa cggtcggtga
      481 aaaagttaat tttaacaaag gaaatcagag agaagatctt acactatcat aagcaaaaat
      541 tttcgcctga aatgatggtt aacaagaagc aagtgaaagt tggtatttca accatctact
      601 actggtttca taatggtcat ttaggattga cgaaggccga catgctttat cccagaaaaa
      661 ggaaaggtgt caagaagcaa gctagtccga actttaagcc ggcaggtaaa tctatcgaag
      721 aacgtcctga cgttattaat cttcgcttgg aaaatggtca ttatgaaatt gataccgtcc
      781 tactgactaa gataaaaaat tattgcctgt t
//
LOCUS       DAVKBK010000142          790 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVKBK010000142 DAVKBK010000000
VERSION     DAVKBK010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.142"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            24..>790
                     /locus_tag="VWX69_002050"
     CDS             24..>790
                     /locus_tag="VWX69_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEU9193305.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQF"
BASE COUNT          250 a          166 c          130 g          244 t
ORIGIN      
        1 aacaactcat tagaaagaat catatggaac aattacattt tatcacaaaa ctgctcgata
       61 ttaaagaccc aaacatcaag attctagata tcatcaatat ggatacccac aaagaaatta
      121 tcgctaagct ggattatgag gctccatctt gccctgattg tggaagtcta atgaagaaat
      181 atgactttca aaaaccgtct aagatccctt acctcgaaac aactggtatg ccttctagaa
      241 ttctccttag aaaacgccgt ttcaagtgct atcactgttc aaaaatgatg gttgctgaga
      301 ctcccctggt aaagaaaaat caccaaatcc ctcgtatcat caaccaaaaa attgctcaaa
      361 agttaattga aaaaatttct atgactgata ttgcccatca gctggccatt tcaacttcaa
      421 ctgtcattcg caagctcaat gactttcact ttgagcatga tttttctcgg cttccaaaga
      481 ttatgtcttg ggatgagtat gccttcacta agggaaagat gagtttcatt gcgcaagatt
      541 ttgataatct taatattatc actgttcttg aaggcagaac acaagctgtc atccgaaatc
      601 actttcttcg ctacgataga gccgttcgtt gtcaagtgaa aatcattacg atggatatgt
      661 ttagtcctta ctatgacttg gctaaacagc tttttccgtg tgctaaaatc gttctagatc
      721 gtttccatat tatccaacat ctcagccgtg ccatgagtcg ttttcgtgtt caaattatga
      781 atcagtttga
//
LOCUS       DAVKBK010000143          786 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVKBK010000143 DAVKBK010000000
VERSION     DAVKBK010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.143"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            205..>786
                     /locus_tag="VWX69_002051"
     CDS             205..>786
                     /locus_tag="VWX69_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193306.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTEL"
BASE COUNT          293 a          138 c          104 g          251 t
ORIGIN      
        1 cctattcaat tactagaact atcacatact caaggtcagc tcacagatga gcaactattt
       61 tggttacaat gtctactaaa tttaagtcaa acaaataatt tagtcaaaat taaaaaaata
      121 gaggaacata aatatgatta caaaacagaa tgtaatagtg ttctacaatt tttactagat
      181 aaaactgtaa attctgaagg aaggatcact tcttcaacag aatttggaaa tttcgtaagt
      241 aatttatcat tccaacacgg aatagctgga ctactgtttc ctctaaataa attgtacccc
      301 ccagaactgg attctaaaat actctctatc atcaagaagg cagtgacaat tagaacgaca
      361 cacacatatg aatatcaata ctcactgcta tttggtgatg caggctatct atggttactc
      421 ctacatttat tttctatcag taaaaatcaa tactatctac aattagcaaa cgtcaccgct
      481 aaaaaattaa tagagaatta tgatactcta gaggaaatag actttgcatt gggaaaatct
      541 ggtgtcctat tatcattaat aaaatactat caatttacca atgacaatac tcttaaaatt
      601 ttcatccaca atagtatagg ggaaatttat cattatttcc tacaaagaga tacagccaaa
      661 gaaagcattt tagactatag ctttgctcat ggatattgtg gaattgcata tgctttattt
      721 gcctattcta aagtcttaga accttctatg ttctataatg atctccatac attccatact
      781 gaatta
//
LOCUS       DAVKBK010000144          743 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVKBK010000144 DAVKBK010000000
VERSION     DAVKBK010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..743
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.144"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            280..498
                     /locus_tag="VWX69_002052"
     CDS             280..498
                     /locus_tag="VWX69_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9193307.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
BASE COUNT          320 a           83 c          128 g          212 t
ORIGIN      
        1 atttaaagat tctttaaaga gtcttatttt gtgatgaaaa tttaatatgt aaatctcaga
       61 cgatagaaat taaaaactct atcgtctttt ttatactcaa aattaggagg taaaaatggt
      121 aaggataaga ggtcccactt aaaacaattt atggcaaaat aaggacggaa taacacaaca
      181 aattctctaa aacaaatcac taaatcaatg taagattgaa tgaaatcaat atttatgcta
      241 taattaaata aatctaatga agaaaaaaag agggatatta tggcacttaa ctataaacca
      301 ttatggatac agttagcaaa aaaaggacta aagaaaacag atgtaatagc tatggcagga
      361 cttacaacaa atgttatggc acaaatggga aaggataaac caattacatt taagaattta
      421 gaaagaatat gtaaggcttt atcttgcact cctaatgata ttattagttt tgaagataat
      481 tttagtgacg aggaatagaa aatgacttta aggacagaag atcaagttag ggattatgca
      541 agagaagtat aggctttaat gaagttgaag aaaacatcaa tcaaggtact ggtcaaataa
      601 ctacttttaa tcaattaggc ttcaagggat attcagataa gccagatggt tggtatttac
      661 ctaaaaatat gaatgatgta gcaataatcc ttgaaacaaa atcagaagaa agagatatta
      721 gcaaacaaat ttttattgat gag
//
LOCUS       DAVKBK010000145          724 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVKBK010000145 DAVKBK010000000
VERSION     DAVKBK010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.145"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..616
                     /locus_tag="VWX69_002053"
     CDS             <1..616
                     /locus_tag="VWX69_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9193308.1"
                     /translation="YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLR
                     DYSGELRFCGDDIKKTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSL
                     EQVGLSVKDFPNNILDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDR
                     RTSLAIERKILDREDLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          267 a           69 c          149 g          239 t
ORIGIN      
        1 ctataagtat ggagataaag aaatattaaa aaacttaaat ttttgttttc aacgtaatga
       61 aaagtattta attttaggtg aaagtggaag cgggaaatct acattattaa aattattgaa
      121 tggctttttg agagattata gtggagaatt gcgattctgc ggggatgata taaaaaaaac
      181 ctcctattta aatatggttt cgaatgttct atatgtagat caaaaagctt atttgtttga
      241 aggtacgatt agagataata ttttattgga agaaaattat actgatgaag aaatactaca
      301 gtctttagag caagttggtt tgagtgtaaa agattttcct aataacattt tagattatta
      361 tgttggtgat gatgggagat tactgtcagg agggcagaaa caaaaaatta ctttagctag
      421 agggctaatt agaaataaga aaatagtatt aattgacgag ggaacttctg ctatcgatag
      481 gagaacttcg ttagcgattg aacgtaagat attagataga gaggatttga ctgtcattat
      541 tgttacccat gctccgcatc cggaacttaa acaatatttt actaagatat atcaatttcc
      601 aaaggatttt atttaagaat ataggggagg gaaacatgag attctattgt gaagcttatg
      661 aggtaattac tgaagagaaa aaagtatact ttaatgatat tgagttagaa gttaagtatt
      721 cctc
//
LOCUS       DAVKBK010000146          694 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVKBK010000146 DAVKBK010000000
VERSION     DAVKBK010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.146"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            286..585
                     /locus_tag="VWX69_002054"
     CDS             286..585
                     /locus_tag="VWX69_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU9193309.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT          257 a          131 c          119 g          187 t
ORIGIN      
        1 agatgtaaca tgtttgcaaa caaagcatac gaacctttag taaaatcatt tccatgaaac
       61 tagaatagag ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
      121 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
      181 cttgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
      241 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
      301 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
      361 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
      421 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
      481 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
      541 accaagaaaa aactgggtgc tttcgctggg aaattacctt tctaaaaaca aggagctaga
      601 acaatgcttg tcgataacaa aggctaagaa aggtgcaaaa atgactctat aatatttgta
      661 gtgggtaaat cccctataga tattatggag ccta
//
LOCUS       DAVKBK010000147          665 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVKBK010000147 DAVKBK010000000
VERSION     DAVKBK010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..665
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.147"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(327..497)
                     /locus_tag="VWX69_002055"
     CDS             complement(327..497)
                     /locus_tag="VWX69_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9193310.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(510..>665)
                     /locus_tag="VWX69_002056"
     CDS             complement(510..>665)
                     /locus_tag="VWX69_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEU9193311.1"
                     /translation="CTQIIVAHRLSTIKDADVIFVMKGGKIVESGNHKYLMDLGGEYY
                     SLYTKRK"
BASE COUNT          226 a          130 c           78 g          231 t
ORIGIN      
        1 atatcttatt tcaatttact atacttactt gacccttttt atactcaatg aaaatcaaag
       61 agcaaactag gaagcgagcc gcaggctgta cttgagtacg gtaaagcaaa gctgacgtgg
      121 tttgaagaga ttttcaaaga gtattaaaca aaaagaaaaa ccgctactcc taagaatagc
      181 gatttaatca tgtttttaag ctactactgt agttgctcta ttatttaagt gttatgaata
      241 acttcaatat ctttaaagct ttttgttaga tttataattt caactatagc catctctact
      301 ccttagttta cagcaaaaaa ttatgcttaa ttcttattgt ttttgtaaac aatcagcgaa
      361 cccaatacta ttccattcaa caagcctaaa gaaataccat attcaactgg aaaatctaaa
      421 aaaattgcaa acactattcc aatcatcact cctagtgagg ctgttgttaa aattacatat
      481 tcattttctt tcttcatttt ctttacacct catttccttt ttgtatataa gctgtagtac
      541 tctccaccaa gatccattaa gtacttatga tttcctgact caacaatctt accacctttc
      601 attacaaaaa taacatccgc atccttaatc gttgacaatc tatgagctac aattatttga
      661 gtaca
//
LOCUS       DAVKBK010000148          633 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.148, whole genome shotgun sequence.
ACCESSION   DAVKBK010000148 DAVKBK010000000
VERSION     DAVKBK010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.148"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            192..410
                     /locus_tag="VWX69_002057"
     CDS             192..410
                     /locus_tag="VWX69_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU9193312.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
BASE COUNT          209 a           77 c          118 g          229 t
ORIGIN      
        1 cggctagttt cctagtttgc tctttggttt tcattgagta taacacattg ttagaagttg
       61 gtttaaattt cctaatcagt ttgttcacat ttaccttcga tatattatat cccatagtta
      121 aggttggtca tacagatgat tatagccatg gagccgtaaa acttagtgtt tctttagttg
      181 acaaagatgc catgaaaaaa atatctgtaa ctgtaatagg atattttgaa ataaatatag
      241 atgaaaatat caccgatatt ctatacgtaa atggtactgc tattctttat ccttatttac
      301 gttctattgt ttcaatagtt tcggcaattg atagcagtga agcaatgttg ctacctacca
      361 ttaatgtttt agagttacta gataaatctc aaccttttga agaagaataa tttattagct
      421 cactaaattg agggtaagga aaagtaaaag cagtaagaaa aatgtcttgc attatacagc
      481 aactttttgg gaatgagtag atggattgaa taaaatttga ttaagagtgg atgatttatc
      541 tgtagattat tattggacag ttagtcttga agtagtctaa gaattaggtt ataatcagta
      601 gaagccttgc taataatgag gaggttagtt tat
//
LOCUS       DAVKBK010000149          629 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.149, whole genome shotgun sequence.
ACCESSION   DAVKBK010000149 DAVKBK010000000
VERSION     DAVKBK010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..629
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.149"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..>629
                     /gene="phtB"
                     /locus_tag="VWX69_002058"
     CDS             <1..>629
                     /gene="phtB"
                     /locus_tag="VWX69_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU9193313.1"
                     /translation="LKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQV
                     AKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKE
                     KGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPH
                     YDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGF"
BASE COUNT          200 a          129 c          139 g          161 t
ORIGIN      
        1 actcaaggat gtctcaagtg ataaagtcaa gttagtggat gatattcttg ccttcttagc
       61 tccgattcgt catccagaac gtttaggaaa accaaatgcg caaattacct acactgatga
      121 tgagattcaa gtagccaagt tggcaggcaa gtacacaaca gaagacggtt atatctttga
      181 tcctcgtgat ataaccagtg atgaggggga tgcctatgta actccacata tgacccatag
      241 ccactggatt aaaaaagata gtttgtctga agctgagaga gcggcagccc aggcttatgc
      301 taaagagaaa ggtttgaccc ctccttcgac agaccatcag gattcaggaa atactgaggc
      361 aaaaggagca gaagctatct acaaccgcgt gaaagcagct aagaaggtgc cacttgatcg
      421 tatgccttac aatcttcaat atactgtaga agtcaaaaac ggtagtttaa tcatacctca
      481 ttatgaccat taccataaca tcaaatttga gtggtttgac gaaggccttt atgaggcacc
      541 taaggggtat actcttgagg atcttttggc gactgtcaag tactatgtcg aacatccaaa
      601 cgaacgtccg cattcagata atggttttg
//
LOCUS       DAVKBK010000150          587 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.150, whole genome shotgun sequence.
ACCESSION   DAVKBK010000150 DAVKBK010000000
VERSION     DAVKBK010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.150"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(207..503)
                     /locus_tag="VWX69_002059"
     CDS             complement(207..503)
                     /locus_tag="VWX69_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEU9193314.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
BASE COUNT          213 a          106 c           76 g          192 t
ORIGIN      
        1 tggataggca gtttcatatt ataacgattc aaagtagcgt aatctactac caaaaaaagt
       61 aaaaataatt tcccttgaaa aggaagatag cttttaaaat agattgacaa acttatgata
      121 acaaaaaaca aaagggttat cccaataaaa ttaagataac ctaaaatact ttcacattct
      181 tttttagaaa gtattttcat ctagttctac catagagctg ctttagcagc acctttcttt
      241 ttcaatatat aaagaactgt tgctgcaata cccgaaccaa tagaacctac tcctgtgatt
      301 gcacctacaa ttgaaattac tgctgtaact gtactataag cactaatcaa attgactaca
      361 gtagcagcag cttttgtcga aattcctaat gtcccagcca acataggaaa agaaacaaca
      421 cctaagctta accaactaat gactgctaac attgctgaaa caataagaaa tttattatga
      481 aattccattc ttttagattt cattttagtg tactcctttt gtatattatg tatgttttat
      541 tgagagttaa ttcgcacatg ttgtattcct aactctcttc aaatgtt
//
LOCUS       DAVKBK010000151          580 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.151, whole genome shotgun sequence.
ACCESSION   DAVKBK010000151 DAVKBK010000000
VERSION     DAVKBK010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..580
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.151"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..>580)
                     /locus_tag="VWX69_002060"
     CDS             complement(<1..>580)
                     /locus_tag="VWX69_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEU9193315.1"
                     /translation="QFLFNFWNYFARNLDNLLIGRLISPSDLGYYDKAYQLSLYPNQI
                     LSQVVTPALHPIMSNFQDNISKIGEVYLQISRIFVIVGIPISAYLYFNAQYVVTFMFG
                     DNWSQSVPVFQILAATIWLQMANSPTGAFYQATNQTKLLFRIGLLTSFINILAIVIGV
                     MLQSIQCVAYMLLISFSLSLVINTLYLTKKVL"
BASE COUNT          231 a           91 c           85 g          173 t
ORIGIN      
        1 tttaatactt tttttgttaa gtaaagagta ttgattacta aactaagact gaaagaaatc
       61 aaaagcatgt acgcaacaca ttggatgctt tgcaacatta caccaataac aatagctaaa
      121 atattaataa aagatgtcaa taagccaatt ctaaacaata actttgtctg attagttgct
      181 tggtaaaatg caccagtagg gctattagcc atttgtaacc aaattgttgc tgctaatatt
      241 tgaaacaccg gaacgctttg ggaccaatta tctccaaaca taaatgtaac aacatattga
      301 gcattaaagt ataaataagc cgaaataggt atgccaacta ttacgaatat tctagaaatc
      361 tgaagataaa cttcgcctat cttactgata ttatcttgaa aattggacat aataggatgc
      421 aatgctggtg tcacaacctg tgataaaatt tgattagggt acaaagataa ttgataagcc
      481 ttatcataat aaccaagatc tgacgggcta atcaatcgtc caattaataa attatctaaa
      541 tttctagcaa aataattcca aaaattaaac aaaaattgga
//
LOCUS       DAVKBK010000152          571 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.152, whole genome shotgun sequence.
ACCESSION   DAVKBK010000152 DAVKBK010000000
VERSION     DAVKBK010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.152"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            <1..504
                     /locus_tag="VWX69_002061"
     CDS             <1..504
                     /locus_tag="VWX69_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HEU9193316.1"
                     /translation="ENALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKI
                     PFIANGDIRTVQEAKQRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFE
                     DKMKIAYEHLKRLINLKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEA
                     LLQLEKA"
BASE COUNT          159 a          156 c          122 g          134 t
ORIGIN      
        1 gaaaatgccc tcgctgctga ggctgcaggt gtttctgccc tcgccatgca tggccgtacc
       61 cgtgaacaaa tgtatactgg ccacgcagac cttgagaccc tgtacaaggt tgcccaagct
      121 ctaaccaaga ttccattcat cgccaacggt gatatccgta ctgtccaaga agccaagcaa
      181 cgcatcgaag aagttggtgc tgacgcagtc atgattggcc gagctgccat gggaaatcct
      241 tacctcttca accaaatcaa ccattacttt gaaacaggag aaatcctacc tgatttgacc
      301 tttgaagaca agatgaagat cgcctacgaa cacttgaaac gattgattaa cctcaaagga
      361 gaaaacgtcg cagttcgtga attccgtggc ctcgctcctc actacctccg tggaacatct
      421 ggcgctgcca aactccgtgg agccatttcg caagctagca ccctggcaga gattgaagct
      481 ctcttgcaat tggagaaggc ttaatagttt aaaacccgta actctcttaa agagtctctt
      541 gagtgccgcc attctttcct catcaaaaaa a
//
LOCUS       DAVKBK010000153          495 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.153, whole genome shotgun sequence.
ACCESSION   DAVKBK010000153 DAVKBK010000000
VERSION     DAVKBK010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.153"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..>495)
                     /locus_tag="VWX69_002062"
     CDS             complement(<1..>495)
                     /locus_tag="VWX69_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9193317.1"
                     /translation="IRKLNDFHFKHDFSRLPEIMSWDEYAFTKGKMSFIAQDFEKLDI
                     ITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYDLARQLFPCAKIVLDRFHI
                     VQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDSRKLSDKHFYRPTFRMHLT
                     NKEIF"
BASE COUNT          164 a           94 c           95 g          142 t
ORIGIN      
        1 aaaaatctct ttattggtta aatgcatacg aaaagtaggg cgataaaaat gtttatcgct
       61 gagtttacga ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct tgtattcatg
      121 agactttcga tccaattgat tcatgatttg aacacgcaca cgactcatag cacggctaag
      181 atgttgtaca atgtgaaagc gatccaacac gattttagca cacgggaaaa gttgtctagc
      241 taagtcatag taaggactaa acatatccat agtaataatt ttgacgcgac atcggacaac
      301 tctatcgtag cgaagaaagt gatttcgaat gatagcttgt gttctaccct caagaacagt
      361 gatgatatcg agcttttcaa aatcttgcgc aatgaagctc atctttccct ttgtaaaagc
      421 atactcatcc caagacataa tctcaggaag acgcgaaaaa tcatgtttaa agtgaaaatc
      481 attgagctta cgaat
//
LOCUS       DAVKBK010000154          411 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.154, whole genome shotgun sequence.
ACCESSION   DAVKBK010000154 DAVKBK010000000
VERSION     DAVKBK010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.154"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
BASE COUNT          166 a           39 c           82 g          124 t
ORIGIN      
        1 tacaatatct tatatataac taatttaaaa attgtctaaa tataatagca aatagagaaa
       61 ataatcagta tttatgaggc agatttggag acttaattga taaaatcaat ttgatacttg
      121 taaaatgaga gtagtagaaa agtttgtgac attaggaagt catattctat atgctggcta
      181 tgaagttggt gtttgaaaag aatatgtaaa agctgatgag acaagtccat tgtaccagtt
      241 gaaaaagaaa ataagcttta aagcatgaca ggaaggaatc tcggataagg agaaaggaaa
      301 gagatagtta agaggtaatc agaggagaat attatctttg gtagctttaa ccattttaaa
      361 ggaatgtata gaattactta aataagactc ctgtctatcc tattgagtag c
//
LOCUS       DAVKBK010000155          336 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00067247
            SAMN33606273-rid17941453.denovo.155, whole genome shotgun sequence.
ACCESSION   DAVKBK010000155 DAVKBK010000000
VERSION     DAVKBK010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606273
            Sequence Read Archive: SRR23727633
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722675.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722675.1
            Genome Coverage       :: 155x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:15:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,063
            CDSs (total)                      :: 2,016
            Genes (coding)                    :: 1,900
            CDSs (with protein)               :: 1,900
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 58 of 116
            Pseudo Genes (incomplete)         :: 53 of 116
            Pseudo Genes (internal stop)      :: 42 of 116
            Pseudo Genes (multiple problems)  :: 29 of 116
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606273-rid17941453.denovo.155"
                     /strain="AUSMDU00067247"
                     /serotype="09N"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST66"
     gene            complement(<1..190)
                     /locus_tag="VWX69_002063"
     CDS             complement(<1..190)
                     /locus_tag="VWX69_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAT RNA binding domain-containing protein"
                     /protein_id="HEU9193318.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMF"
BASE COUNT          110 a           57 c           39 g          130 t
ORIGIN      
        1 taaacatctc tgtaaaacgg gtcatattat ctctattttt gagaaaaaaa cttttctcaa
       61 tatcaattgg atttacttta tctccaattt ttcttccaaa agctattccc cttccaaaaa
      121 gaagaatatc gatatctttt ttactttgcg caattacggc attgtggttt agtattcgtt
      181 ttatgatcat aaaatttccc ttttaaaata aaaggaacct acttaaaaac atcaagaaac
      241 ttcttccgat gtgattaaat aggttcctgc tcacttgtat tagtgataac atccttttat
      301 ttcaattttt aatggtgaca tgaagcttaa ataatt
//
